…cle cells belonging to the zinc transporter ZIP9 subfamily (SLC39A9) encoding a protein with characteristics of a membrane androgen receptor (mAR). Here, we demonstrate that human ZIP9 expressed in MDA-MB-468 breast cancer cells and stably overexpressed in human prostate cancer P…
Structural basis for L-isoaspartyl-containing protein recognition by the human PCMTD1 cullin-RING E3 ubiquitin ligase. J Biol Chem. 2025 11; 301(11):110735. Pang EZ, Zhao B, Flowers C, Oroudjeva E, Winter JB, Pandey V, Sawaya MR, Wohlschlegel J , Loo JA , Rodriguez JA , Clarke SG…
…by others The importance of being the HGNC Article Open access 15 November 2022 Protein-Coding and Noncoding RNA Genes Chapter The Emerging Role of Long Noncoding RNAs in Human Disease Chapter Explore related subjects Discover the latest articles, books and news in related subjec…
…lities through experiments on sequences (text), images (pathology), and graphs (protein structures), outperforming baseline attribution methods by up to 26.3 points in mean localization AUPRC. We also demonstrate how prospector heads enable improved interpretation and discovery o…
…to the central nervous system (CNS), allowing stable expression of an exogenous protein, short hairpin RNA, or other genomic material. The benefits of viral vectors include site-specific expression, delivery of transgenes to dividing and nondividing cells, stable transgene expres…
…dult ES proteome and a profile of H. polygyrus egg-released material. While 135 proteins are shared between L4 and adult ES, 72 are L4 ES-specific; L4-specific proteins correspond to those whose transcription is restricted to larval stages, while shared proteins are generally tra…
…gi apparatus is to ceptor and are localized between the ER and Golgi ap- modify proteins and lipids synthesized in the ER and paratus. An association of Xklp3 with the recycling sort them to their final destination. The steady-state compartment is further supported by a biochemic…
…d Receptor-Derived Peptide Mimics Neuronal Anti-Apoptotic Activity of Activated Protein C. Bioengineering (Basel). 2025 Aug 22; 12(9). Sagare A , Kim Y, Kisler K, Rust R , Mack WJ , Fernández JA, Zlokovic BV , Griffin JH. PMID: 41007144; PMCID: PMC12467444 . View in: PubMed Menti…
…V., Morelli, X., and Roche, P. 2P2Idb - database dedicated to the modulation of protein-protein interactions database summary 3D rRNA modification maps Locations of modified rRNA nucleotides within the 3D structure of the ribosome database summary 3D-Footprint Bruno Contreras-Mor…
…ly-distinct enzymes, i.e., a kinase, a guanosine triphosphatase and a ubiquitin protein hydrolase, which function in disparate biochemical pathways, that can also act in concert to mediate a series of redox reactions. Each enzyme manifests a second, noncanonical function—transnit…
…able to other biological tissues and taxa. 1 Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark. 2 Globe institute, University of Copenhagen, Copenhagen, Denmark. 3 Institute of Conservation, Royal Danish Academy, Copenhagen, Denmar…
… methylate 4 bp sequences containing a CpG dinucleotide, to a three zinc finger protein recognising a 9 bp DNA sequence. DNA methylation analyses demonstrate specific DNA methylation by both enzymes at target sites comprising adjacent methyltransf erase and zinc finger subsites, …
…ano Jr. and Rena Santizo Proximate composition of both the raw dried powder and protein concentrate of Ulva lactuca in in ... more Proximate composition of both the raw dried powder and protein concentrate of Ulva lactuca in in vivo assays of apparent digestibility of dry matter …
…athogen, zot, SPI, T6SS, Phylogenetic, Enterobacteriaceae, Sequence, Evolution, Protein, Strain, Variation, Virulence, Infection, Protein modelling * Correspondence: [email protected] 1 Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur…
…sign, Directed Evolution and Computational Study of Heme-Binding Helical Bundle Protein Catalysts for Biocatalytic Enantioselective Ge-H Insertion. J Am Chem Soc. 2025 Nov 05; 147(44):40869-40878. Huang W, Adornato GM, Horst M, Alturaifi TM, Hou K, Liu P, DeGrado WF , Yang Y. PMI…