A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway - PMC

Christian Praetorius

¹Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland

Christine Grill

¹Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland

Simon N Stacey

²Decode Genetics, Sturlugata 8, 101 Reykjavik, Iceland

Alexander M Metcalf

³Institute for Molecular Bioscience, University of Queensland, Brisbane, Qld 4072, Australia

David U Gorkin

⁴McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N. Broadway, Baltimore, MD 21205, USA

⁵Predoctoral Training Program in Human Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA

Kathleen C Robinson

⁶Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA

Eric Van Otterloo

⁷Anatomy and Cell Biology, University of Iowa, 357 Medical Research Center, Iowa City, IA 52242-1101, USA

Reuben SQ Kim

³Institute for Molecular Bioscience, University of Queensland, Brisbane, Qld 4072, Australia

⁸The School of Biomedical Sciences, University of Queensland, Brisbane, Qld 4072, Australia

Kristin Bergsteinsdottir

¹Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland

Margret H Ogmundsdottir

¹Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland

Erna Magnusdottir

¹Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland

Pravin J Mishra

⁹Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bldg 37, Room 5002, 37 Convent Drive, Bethesda, MD 20892, USA

Sean R Davis

¹⁰Genetics Branch, National Cancer Institute, Bldg 37, Room 6138, 37 Convent Drive, Bethesda, MD 20892, USA

Theresa Guo

⁹Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bldg 37, Room 5002, 37 Convent Drive, Bethesda, MD 20892, USA

M Raza Zaidi

⁹Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bldg 37, Room 5002, 37 Convent Drive, Bethesda, MD 20892, USA

Agnar S Helgason

²Decode Genetics, Sturlugata 8, 101 Reykjavik, Iceland

Martin I Sigurdsson

¹Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland

Paul S Melzer

¹⁰Genetics Branch, National Cancer Institute, Bldg 37, Room 6138, 37 Convent Drive, Bethesda, MD 20892, USA

Glenn Merlino

⁹Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bldg 37, Room 5002, 37 Convent Drive, Bethesda, MD 20892, USA

Valerie Petit

¹¹Institut Curie, Centre de Recherche, Developmental Genetics of Melanocytes, Orsay, 91405, France

Lionel Larue

¹¹Institut Curie, Centre de Recherche, Developmental Genetics of Melanocytes, Orsay, 91405, France

Stacie K Loftus

¹²Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

David R Adams

¹³Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

Ulduz Sobhiafshar

¹⁴Laboratory of Genome Regulation, Department of Molecular Biology and Genetics, BoğaziçI University, Bebek 34342, Istanbul, Turkey

N C Tolga Emre

¹⁴Laboratory of Genome Regulation, Department of Molecular Biology and Genetics, BoğaziçI University, Bebek 34342, Istanbul, Turkey

William J Pavan

¹²Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

Robert Cornell

⁷Anatomy and Cell Biology, University of Iowa, 357 Medical Research Center, Iowa City, IA 52242-1101, USA

Aaron G Smith

³Institute for Molecular Bioscience, University of Queensland, Brisbane, Qld 4072, Australia

⁸The School of Biomedical Sciences, University of Queensland, Brisbane, Qld 4072, Australia

Andrew S McCallion

⁴McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N. Broadway, Baltimore, MD 21205, USA

David E Fisher

⁶Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA

Kari Stefansson

²Decode Genetics, Sturlugata 8, 101 Reykjavik, Iceland

Richard A Sturm

³Institute for Molecular Bioscience, University of Queensland, Brisbane, Qld 4072, Australia

Eiríkur Steingrímsson

¹Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland

¹Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland

²Decode Genetics, Sturlugata 8, 101 Reykjavik, Iceland

³Institute for Molecular Bioscience, University of Queensland, Brisbane, Qld 4072, Australia

⁴McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N. Broadway, Baltimore, MD 21205, USA

⁵Predoctoral Training Program in Human Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA

⁶Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA

⁷Anatomy and Cell Biology, University of Iowa, 357 Medical Research Center, Iowa City, IA 52242-1101, USA

⁸The School of Biomedical Sciences, University of Queensland, Brisbane, Qld 4072, Australia

⁹Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bldg 37, Room 5002, 37 Convent Drive, Bethesda, MD 20892, USA

¹⁰Genetics Branch, National Cancer Institute, Bldg 37, Room 6138, 37 Convent Drive, Bethesda, MD 20892, USA

¹¹Institut Curie, Centre de Recherche, Developmental Genetics of Melanocytes, Orsay, 91405, France

¹²Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

¹³Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

¹⁴Laboratory of Genome Regulation, Department of Molecular Biology and Genetics, BoğaziçI University, Bebek 34342, Istanbul, Turkey