Alec C. Kimmelman
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Alec C. Kimmelman,
MD, PhD
Dean and Chief Executive Officer
Laura and Isaac Perlmutter Professor of Radiation Oncology, Department of Radiation Oncology
Positions & Education
Positions
Laura and Isaac Perlmutter Professor of Radiation Oncology,
Department of Radiation Oncology at NYU Grossman School of Medicine
Dean and Chief Executive Officer
Graduate Education
MD from Mount Sinai School of Medicine
PhD from Mount Sinai School of Medicine
Residency And Fellowship Training
Residency, Brigham and Women's Hospital (Harvard Medical School) NIH, Radiation Oncology
Contact
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Selected Publications
Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux
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Assi, Mohamad; Wang, Ruohong; Kawaler, Emily A; Sohn, Albert S W; Zahidunnabi Dewan, M; Kalfakakou, Despoina; Encarnacion-Rosado, Joel; Kapner, Kevin S; Ganguly, Koelina; Paulo, Joao A; Simeone, Diane M; Aguirre, Andrew J; Banh, Robert S; Kimmelman, Alec C
Cell.
2026 Feb 16;
Clinical and translational results from a phase 1 trial of gemcitabine/nab-paclitaxel with nivolumab/ipilimumab or hydroxychloroquine/ipilimumab in untreated metastatic pancreatic adenocarcinoma
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O'Reilly, Eileen M; Cabanski, Christopher R; Lyman, Jaclyn P; Wainberg, Zev A; Fisher, George A; Wolff, Robert A; Ko, Andrew H; O'Hara, Mark H; Spencer, Christine N; Yu, Jia Xin; Da Silva, Diane M; Padrón, Lacey J; Arnott, Jamie; Fairchild, Justin; Moore, Jonni S; Peng, Brandon; Hoos, William A; O'Donnell-Tormey, Jill; Boffo, Silvia; Dugan, Ute; Kimmelman, Alec C; Amaravadi, Ravi K; Vonderheide, Robert H
Journal for immunotherapy of cancer.
2026 Jan 30;
14(1):
IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma
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Karakousi, Triantafyllia; Cristaldi, Vanessa; Lopes de Oliveira, Maria Luiza; Delclaux, Ines; Besson, Naomi R; Geraldo, Luiz Henrique; González-Robles, Tania J; McDonnough, Devyon R; Martinez-Krams, Daniel; da Silva, Gabrielle; Breazeale, Alec P; Encarnacion-Rosado, Joel; Pozniak, Joanna; Qiu, Shi; Illa Bochaca, Irineu; Kaiza, Medard E; Kim, Hye Mi; Bruno, Tullia C; Reizis, Boris; Moshiri, Ata S; Kimmelman, Alec C; Ruggles, Kelly V; Osman, Iman; Marine, Jean-Christophe; Chandel, Navdeep S; Lund, Amanda W
Cancer cell.
2026 Jan 22;
Serine tRNAs compete to regulate the mRNA translation of serine-sensitive codons
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Costiniti, Veronica; Tran, Wyatt C; Babu, Nandhini Rajesh; Kanshin, Evgeny; Ueberheide, Beatrix; Kimmelman, Alec C; Banh, Robert S
Science advances.
2025 Nov 14;
11(46):eady4521
Author Correction: Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
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Tintelnot, Joseph; Xu, Yang; Lesker, Till R; Schönlein, Martin; Konczalla, Leonie; Giannou, Anastasios D; Pelczar, Penelope; Kylies, Dominik; Puelles, Victor G; Bielecka, Agata A; Peschka, Manuela; Cortesi, Filippo; Riecken, Kristoffer; Jung, Maximilian; Amend, Lena; Bröring, Tobias S; Trajkovic-Arsic, Marija; Siveke, Jens T; Renné, Thomas; Zhang, Danmei; Boeck, Stefan; Strowig, Till; Uzunoglu, Faik G; Güngör, Cenap; Stein, Alexander; Izbicki, Jakob R; Bokemeyer, Carsten; Sinn, Marianne; Kimmelman, Alec C; Huber, Samuel; Gagliani, Nicola
Nature.
2025 May;
641(8065):E12-E13
Genetics and biology of pancreatic ductal adenocarcinoma
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Ying, Haoqiang; Kimmelman, Alec C; Bardeesy, Nabeel; Kalluri, Raghu; Maitra, Anirban; DePinho, Ronald A
Genes & development.
2025 Jan 07;
39(1-2):36-63
Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial-Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma
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Guinn, Samantha; Kinny-Köster, Benedict; Tandurella, Joseph A; Mitchell, Jacob T; Sidiropoulos, Dimitrios N; Loth, Melanie; Lyman, Melissa R; Pucsek, Alexandra B; Zabransky, Daniel J; Lee, Jae W; Kartalia, Emma; Ramani, Mili; Seppälä, Toni T; Cherry, Christopher; Suri, Reecha; Zlomke, Haley; Patel, Jignasha; He, Jin; Wolfgang, Christopher L; Yu, Jun; Zheng, Lei; Ryan, David P; Ting, David T; Kimmelman, Alec; Gupta, Anuj; Danilova, Ludmila; Elisseeff, Jennifer H; Wood, Laura D; Stein-O'Brien, Genevieve; Kagohara, Luciane T; Jaffee, Elizabeth M; Burkhart, Richard A; Fertig, Elana J; Zimmerman, Jacquelyn W
Cancer research.
2024 May 02;
84(9):1517-1533
The Role of Stroma in Cancer Metabolism
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Kimmelman, Alec C; Sherman, Mara H
Cold Spring Harbor perspectives in medicine.
2024 May 02;
14(5):
See All Publications
(130)
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Read Story
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Read Story
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Perlmutter Cancer Center Once Again Earns Top Award from NCI
Read Story
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