Kyle P. Messier, Ph.D. | National Institute of Environmental Health Sciences Skip Navigation Kyle P. Messier, Ph.D. Close the left navigation Add Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS. Visit the NTP Website Spatiotemporal Exposures and Toxicology Group Kyle P. Messier, Ph.D. Stadtman Investigator; Leader, Spatiotemporal Exposures and Toxicology Tel 984-287-3215 [email protected] Kyle Messier is a Stadtman Tenure-Track Investigator at the National Institute of Environmental Health Sciences (NIEHS) in the Division of Translational Toxicology (DTT). He leads the Spatiotemporal Exposures and Toxicology group, within the Predictive Toxicology Branch. The group, has a broad interest in geospatial exposomics and risk mapping. Key areas of research include (1) Spatiotemporal exposure mapping of environmental and climate variables (e.g. chemical mixtures, social, behavioral, environmental, and climate factors); (2) Source-to-outcome modeling, or GeoTox, which is the integration of geospatial exposures, toxicokinetic modeling, and non-animal toxicological data such as high-through in vitro screen assays to develop mechanistically-informed risk maps; and (3) Developing and promoting software and computational best-practices such as open-source code for the environmental health sciences.” Recent Publications Marquès E, Messier K. Improved High Resolution Heat Exposure Assessment With Personal Weather Stations and Spatiotemporal Bayesian Models. GeoHealth 2025 Sep;9(9):e2025GH001451. Abstract Marquès E, Messier K. Improved High Resolution Heat Exposure Assessment With Personal Weather Stations and Spatiotemporal Bayesian Models. GeoHealth. 2025 Sep Clark L, Zilber D, Schmitt C, Fargo D, Reif D, Motsinger-Reif A, Messier K. A review of geospatial exposure models and approaches for health data integration. Journal of exposure science & environmental epidemiology 2025 Apr;35(2):131-148. Abstract Clark L, Zilber D, Schmitt C, Fargo D, Reif D, Motsinger-Reif A, Messier K. A review of geospatial exposure models and approaches for health data integration. Journal of exposure science & environmental epidemiology. 2025 Apr Messier K, Reif D, Marvel S. The GeoTox Package: open-source software for connecting spatiotemporal exposure to individual and population-level risk. Human genomics 2025 Jan 18;19(1):5. Abstract Messier K, Reif D, Marvel S. The GeoTox Package: open-source software for connecting spatiotemporal exposure to individual and population-level risk. Human genomics. 2025 Jan 18 Zilber D, Messier K, House J, Parham F, Auerbach S, Wheeler M. Bayesian gene set benchmark dose estimation for "omic" responses. Bioinformatics (Oxford, England) 2024 Dec 26;41(1):. Abstract Zilber D, Messier K, House J, Parham F, Auerbach S, Wheeler M. Bayesian gene set benchmark dose estimation for "omic" responses. Bioinformatics (Oxford, England). 2024 Dec 26 Messier K, Reif D, Marvel S. The GeoTox Package: Open-source software for connecting spatiotemporal exposure to individual and population-level risk. medRxiv : the preprint server for health sciences 2024 Nov 20 [Epub ahead of print]. Abstract Messier K, Reif D, Marvel S. The GeoTox Package: Open-source software for connecting spatiotemporal exposure to individual and population-level risk. medRxiv : the preprint server for health sciences. 2024 Nov 20 More Recent Publications from PubMed Back to Top Last Reviewed: December 19, 2025