Scott S. Auerbach, Ph.D. | National Institute of Environmental Health Sciences
Source: https://www.niehs.nih.gov/research/atniehs/labs/ptb/staff/auerbach
Archived: 2026-04-23 17:19
Scott S. Auerbach, Ph.D. | National Institute of Environmental Health Sciences
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Scott S. Auerbach, Ph.D.
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Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Visit the NTP Website
Toxicoinformatics Group
Scott S. Auerbach, Ph.D.
Leader, Toxicoinformatics
Tel 984-287-3108
Fax 919-541-3647
[email protected]
Scott S. Auerbach, Ph.D., DABT is a Molecular Toxicologist that leads the Toxicoinformatics Group within the Predictive Toxicology Branch of the Division of Translational Toxicology at NIEHS. In additional to his role as Toxicoinformatics Group Leader, he leads efforts related to the analysis and interpretation of multivariate data sets (i.e., microarray, RNA-seq, High-throughput screening) for purposes of informing toxicological assessment.
His specific responsibilities include:
Oversight of the NTP
DrugMatrix
resource and genomic dose-response analysis tools,
BMDExpress 2
and
BMDExpress 3
Multivariate data analysis and modeling with the purpose of prioritizing chemicals for targeted toxicological assessment
Use of machine learning approaches to develop multivariate data models that diagnosis and predict toxicological pathology and disease
Application of short-term in vivo transcriptomic studies to allow for the identification of genomic benchmark dose values and mechanistic characterization
Pathway and network level characterization of toxicity related omics results with the goal of understanding mechanisms of target organ toxicity
Use of literature mining and data driven bioinformatics approaches to understand the relationship between chemogenomic perturbations and disease
High dimensional data analysis and visualization via network topology
Auerbach also helped lead the NTP team's toxicology efforts related to the
West Virginia chemical spill
that occurred in 2014
Leadership of a research group that has developed numerous tools and resources for analyzing and accessing predictive toxicology data
Auerbach received a B.S. in biochemistry and molecular biology from the Pennsylvania State University, State College, Pennsylvania and a Ph.D. in pharmacology from the University of Washington, Seattle, Washington.
Complete list of publications
Recent Publications
Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13
NIEHS Report Series
.
2026 Apr [Epub ahead of print].
[
Abstract
Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13 NIEHS Report Series. 2026 Apr
]
Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12
NIEHS Report Series
.
2026 Apr [Epub ahead of print].
[
Abstract
Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12 NIEHS Report Series. 2026 Apr
]
Bommarito P, Taylor K, Rooney A, Addo K, Auerbach S, Blain R, Ferguson K, Gaston S, Hall S, Jackson C, Lemeris C, Silva R, Tracy W, Walker V, Howdeshell K. Systematic evidence map on the association between exposure to personal care products and fetal growth.
Environment international
.
2026 Mar;209:110147.
[
Abstract
Bommarito P, Taylor K, Rooney A, Addo K, Auerbach S, Blain R, Ferguson K, Gaston S, Hall S, Jackson C, Lemeris C, Silva R, Tracy W, Walker V, Howdeshell K. Systematic evidence map on the association between exposure to personal care products and fetal growth. Environment international. 2026 Mar
]
Cong G, Patton R, Chao F, Svoboda D, Erickson J, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Auerbach S. Transplatformer: translating toxicogenomic profiles between generations of platforms.
BMC bioinformatics
.
2026 Jan 30;27(1):.
[
Abstract
Cong G, Patton R, Chao F, Svoboda D, Erickson J, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Auerbach S. Transplatformer: translating toxicogenomic profiles between generations of platforms. BMC bioinformatics. 2026 Jan 30
]
Pannala V, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Casey W, Auerbach S, Wallqvist A. Fenofibrate differentially activates PPARα-mediated lipid metabolism in rat kidney and liver.
Scientific reports
.
2025 Oct 22;15(1):36842.
[
Abstract
Pannala V, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Casey W, Auerbach S, Wallqvist A. Fenofibrate differentially activates PPARα-mediated lipid metabolism in rat kidney and liver. Scientific reports. 2025 Oct 22
]
NTP Reports
National Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice.
National Toxicology Program technical report series
.
2023 Jun [Epub ahead of print].
[
Abstract
National Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2023 Jun
]
National Toxicology Program. NTP Immunotoxicity Technical Report on the Dermal Hypersensitivity and Irritancy Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) and Crude 4-Methylcyclohexanemethanol Administered Topically to Female BALB/c Mice: Immunotoxicity Report 01
NTP Immunotoxicity Reports
.
2020 Jul [Epub ahead of print].
[
Abstract
National Toxicology Program. NTP Immunotoxicity Technical Report on the Dermal Hypersensitivity and Irritancy Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) and Crude 4-Methylcyclohexanemethanol Administered Topically to Female BALB/c Mice: Immunotoxicity Report 01 NTP Immunotoxicity Reports. 2020 Jul
]
National Toxicology Program. NTP Developmental and Reproductive Toxicity Technical Report on the Prenatal Development Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats (Gavage Studies): DART Report 02
NTP Developmental and Reproductive Toxicity Reports
.
2020 Jun [Epub ahead of print].
[
Abstract
National Toxicology Program. NTP Developmental and Reproductive Toxicity Technical Report on the Prenatal Development Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats (Gavage Studies): DART Report 02 NTP Developmental and Reproductive Toxicity Reports. 2020 Jun
]
National Toxicology Program. Toxicology and carcinogenesis studies of 2-hydroxy-4-methoxybenzophenone administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice.
National Toxicology Program technical report series
.
2020 May [Epub ahead of print].
[
Abstract
National Toxicology Program. Toxicology and carcinogenesis studies of 2-hydroxy-4-methoxybenzophenone administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2020 May
]
National Toxicology Program. NTP Research Report on In Vivo Repeat Dose Biological Potency Study of Triphenyl Phosphate (CAS No. 115-86-6) in Male Sprague Dawley Rats (Hsd: Sprague Dawley SD) (Gavage Studies): Research Report 8
NTP Research Reports
.
2018 Dec [Epub ahead of print].
[
Abstract
National Toxicology Program. NTP Research Report on In Vivo Repeat Dose Biological Potency Study of Triphenyl Phosphate (CAS No. 115-86-6) in Male Sprague Dawley Rats (Hsd: Sprague Dawley SD) (Gavage Studies): Research Report 8 NTP Research Reports. 2018 Dec
]
More Recent Publications from PubMed
Related Links
Computational toxicology featured in special journal issue
- Environmental Factor, March 2021
Back
to Top
Last Reviewed: December 19, 2025
Skip Navigation
Scott S. Auerbach, Ph.D.
Close the left navigation
Add
Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Visit the NTP Website
Toxicoinformatics Group
Scott S. Auerbach, Ph.D.
Leader, Toxicoinformatics
Tel 984-287-3108
Fax 919-541-3647
[email protected]
Scott S. Auerbach, Ph.D., DABT is a Molecular Toxicologist that leads the Toxicoinformatics Group within the Predictive Toxicology Branch of the Division of Translational Toxicology at NIEHS. In additional to his role as Toxicoinformatics Group Leader, he leads efforts related to the analysis and interpretation of multivariate data sets (i.e., microarray, RNA-seq, High-throughput screening) for purposes of informing toxicological assessment.
His specific responsibilities include:
Oversight of the NTP
DrugMatrix
resource and genomic dose-response analysis tools,
BMDExpress 2
and
BMDExpress 3
Multivariate data analysis and modeling with the purpose of prioritizing chemicals for targeted toxicological assessment
Use of machine learning approaches to develop multivariate data models that diagnosis and predict toxicological pathology and disease
Application of short-term in vivo transcriptomic studies to allow for the identification of genomic benchmark dose values and mechanistic characterization
Pathway and network level characterization of toxicity related omics results with the goal of understanding mechanisms of target organ toxicity
Use of literature mining and data driven bioinformatics approaches to understand the relationship between chemogenomic perturbations and disease
High dimensional data analysis and visualization via network topology
Auerbach also helped lead the NTP team's toxicology efforts related to the
West Virginia chemical spill
that occurred in 2014
Leadership of a research group that has developed numerous tools and resources for analyzing and accessing predictive toxicology data
Auerbach received a B.S. in biochemistry and molecular biology from the Pennsylvania State University, State College, Pennsylvania and a Ph.D. in pharmacology from the University of Washington, Seattle, Washington.
Complete list of publications
Recent Publications
Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13
NIEHS Report Series
.
2026 Apr [Epub ahead of print].
[
Abstract
Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13 NIEHS Report Series. 2026 Apr
]
Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12
NIEHS Report Series
.
2026 Apr [Epub ahead of print].
[
Abstract
Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12 NIEHS Report Series. 2026 Apr
]
Bommarito P, Taylor K, Rooney A, Addo K, Auerbach S, Blain R, Ferguson K, Gaston S, Hall S, Jackson C, Lemeris C, Silva R, Tracy W, Walker V, Howdeshell K. Systematic evidence map on the association between exposure to personal care products and fetal growth.
Environment international
.
2026 Mar;209:110147.
[
Abstract
Bommarito P, Taylor K, Rooney A, Addo K, Auerbach S, Blain R, Ferguson K, Gaston S, Hall S, Jackson C, Lemeris C, Silva R, Tracy W, Walker V, Howdeshell K. Systematic evidence map on the association between exposure to personal care products and fetal growth. Environment international. 2026 Mar
]
Cong G, Patton R, Chao F, Svoboda D, Erickson J, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Auerbach S. Transplatformer: translating toxicogenomic profiles between generations of platforms.
BMC bioinformatics
.
2026 Jan 30;27(1):.
[
Abstract
Cong G, Patton R, Chao F, Svoboda D, Erickson J, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Auerbach S. Transplatformer: translating toxicogenomic profiles between generations of platforms. BMC bioinformatics. 2026 Jan 30
]
Pannala V, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Casey W, Auerbach S, Wallqvist A. Fenofibrate differentially activates PPARα-mediated lipid metabolism in rat kidney and liver.
Scientific reports
.
2025 Oct 22;15(1):36842.
[
Abstract
Pannala V, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Casey W, Auerbach S, Wallqvist A. Fenofibrate differentially activates PPARα-mediated lipid metabolism in rat kidney and liver. Scientific reports. 2025 Oct 22
]
NTP Reports
National Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice.
National Toxicology Program technical report series
.
2023 Jun [Epub ahead of print].
[
Abstract
National Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2023 Jun
]
National Toxicology Program. NTP Immunotoxicity Technical Report on the Dermal Hypersensitivity and Irritancy Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) and Crude 4-Methylcyclohexanemethanol Administered Topically to Female BALB/c Mice: Immunotoxicity Report 01
NTP Immunotoxicity Reports
.
2020 Jul [Epub ahead of print].
[
Abstract
National Toxicology Program. NTP Immunotoxicity Technical Report on the Dermal Hypersensitivity and Irritancy Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) and Crude 4-Methylcyclohexanemethanol Administered Topically to Female BALB/c Mice: Immunotoxicity Report 01 NTP Immunotoxicity Reports. 2020 Jul
]
National Toxicology Program. NTP Developmental and Reproductive Toxicity Technical Report on the Prenatal Development Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats (Gavage Studies): DART Report 02
NTP Developmental and Reproductive Toxicity Reports
.
2020 Jun [Epub ahead of print].
[
Abstract
National Toxicology Program. NTP Developmental and Reproductive Toxicity Technical Report on the Prenatal Development Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) in Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats (Gavage Studies): DART Report 02 NTP Developmental and Reproductive Toxicity Reports. 2020 Jun
]
National Toxicology Program. Toxicology and carcinogenesis studies of 2-hydroxy-4-methoxybenzophenone administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice.
National Toxicology Program technical report series
.
2020 May [Epub ahead of print].
[
Abstract
National Toxicology Program. Toxicology and carcinogenesis studies of 2-hydroxy-4-methoxybenzophenone administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2020 May
]
National Toxicology Program. NTP Research Report on In Vivo Repeat Dose Biological Potency Study of Triphenyl Phosphate (CAS No. 115-86-6) in Male Sprague Dawley Rats (Hsd: Sprague Dawley SD) (Gavage Studies): Research Report 8
NTP Research Reports
.
2018 Dec [Epub ahead of print].
[
Abstract
National Toxicology Program. NTP Research Report on In Vivo Repeat Dose Biological Potency Study of Triphenyl Phosphate (CAS No. 115-86-6) in Male Sprague Dawley Rats (Hsd: Sprague Dawley SD) (Gavage Studies): Research Report 8 NTP Research Reports. 2018 Dec
]
More Recent Publications from PubMed
Related Links
Computational toxicology featured in special journal issue
- Environmental Factor, March 2021
Back
to Top
Last Reviewed: December 19, 2025