Molecular Microscopy Consortium | National Institute of Environmental Health Sciences Skip Navigation Molecular Microscopy Consortium Close the left navigation Add Services The Molecular Microscopy Consortium allows scientists from NIEHS, the University of North Carolina at Chapel Hill, and Duke University to use single particle cryo-electron microscopy and other tools in molecular microscopy to solve macromolecular structures at the atomic level. Cryo-EM requires smaller quantities of material than other structural methods and is especially suitable for the study of hard to crystallize large macromolecular complexes and membrane proteins. Available Training Local scientists interested in receiving training from the NIEHS Cryo-Electron Microscopy Core Facility must contact Mario Borgnia This video shows how the NIEHS Cryo-EM Facility generates 3D images of large proteins. (3:53) Background Types of projects we do: Data collection Specimen preparation Experimental design advice and training Image processing and interpretation Scientific Staff Mario J. Borgnia, Ph.D. Director, Molecular Microscopy Consortium Tel 984-287-3447 [email protected] Mary E. Offner Fellow - IRTA Postbaccalaureate Tel 984-287-4737 [email protected] Back to Top Last Reviewed: March 19, 2026