Mouse Embryo Phenotyping & Special Techniques Group | National Institute of Environmental Health Sciences Skip Navigation Mouse Embryo Phenotyping & Special Techniques Group Close the left navigation Add Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS. Visit the NTP Website Robert C. Sills, D.V.M., Ph.D. Chief, Comparative and Molecular Pathogenesis Branch Tel 984-287-3839 [email protected] The primary focus of the NIEHS Mouse Embryo Phenotyping Core is to provide expertise and support for the evaluation of pathology phenotypes of genetically altered mice. Efforts include evaluation of the causes of embryonic lethal phenotypes. Assistance is provided with the collection, histologic processing and pathological assessment of embryos. Recent Publications Xu M, Li J, Hsiao Y, Kovi R, Li J, Klimczak L, Riva L, Adams D, Bushel P, Merrick B, Gordenin D, Bucher J, Sills R, Pandiri A. Environmental carcinogens often exacerbate endogenous mutagenic processes to enhance tumor promotion. Cell reports 2025 Jul 22;44(7):115978. Abstract Xu M, Li J, Hsiao Y, Kovi R, Li J, Klimczak L, Riva L, Adams D, Bushel P, Merrick B, Gordenin D, Bucher J, Sills R, Pandiri A. Environmental carcinogens often exacerbate endogenous mutagenic processes to enhance tumor promotion. Cell reports. 2025 Jul 22 Brooks A, Vornoli A, Kovi R, Ton T, Xu M, Mashal A, Tibaldi E, Gnudi F, Li J, Sills R, Bucher J, Mandrioli D, Belpoggi F, Pandiri A. Genetic profiling of rat gliomas and cardiac schwannomas from life-time radiofrequency radiation exposure study using a targeted next-generation sequencing gene panel. PloS one 2024;19(1):e0296699. Abstract Brooks A, Vornoli A, Kovi R, Ton T, Xu M, Mashal A, Tibaldi E, Gnudi F, Li J, Sills R, Bucher J, Mandrioli D, Belpoggi F, Pandiri A. Genetic profiling of rat gliomas and cardiac schwannomas from life-time radiofrequency radiation exposure study using a targeted next-generation sequencing gene panel. PloS one. 2024 Panzacchi S, Belpoggi F, Bua L, Bucher J, Cora M, De Angelis L, Falcioni L, Gnudi F, Mandrioli D, Manservigi M, Manzoli I, Masten S, Menghetti I, Mutlu E, Roberts G, Shipkowski K, Sills R, Stout M, Strollo V, Tibaldi E, Tracy J, Vornoli A, Waidyanatha S. NIEHS Report on the Toxicity Studies of Nicotine Bitartrate Dihydrate (CASRN 6019-06-3) Administered in Drinking Water to Sprague Dawley Rats and Swiss Mice: NIEHS Report 11 NIEHS Report Series 2024 Oct [Epub ahead of print]. Abstract Panzacchi S, Belpoggi F, Bua L, Bucher J, Cora M, De Angelis L, Falcioni L, Gnudi F, Mandrioli D, Manservigi M, Manzoli I, Masten S, Menghetti I, Mutlu E, Roberts G, Shipkowski K, Sills R, Stout M, Strollo V, Tibaldi E, Tracy J, Vornoli A, Waidyanatha S. NIEHS Report on the Toxicity Studies of Nicotine Bitartrate Dihydrate (CASRN 6019-06-3) Administered in Drinking Water to Sprague Dawley Rats and Swiss Mice: NIEHS Report 11 NIEHS Report Series. 2024 Oct Izawa T, Travlos G, Cortes R, Clayton N, Sills R, Pandiri A. Absence of Increased Susceptibility to Acetaminophen-Induced Liver Injury in a Diet-Induced NAFLD Mouse Model. Toxicologic pathology 2023 Apr;51(3):112-125. Abstract Izawa T, Travlos G, Cortes R, Clayton N, Sills R, Pandiri A. Absence of Increased Susceptibility to Acetaminophen-Induced Liver Injury in a Diet-Induced NAFLD Mouse Model. Toxicologic pathology. 2023 Apr Ton T, Hong H, Kovi R, Shockley K, Peddada S, Gerrish K, Janardhan K, Flake G, Stout M, Sills R, Pandiri A. Chronic Inhalation Exposure to Antimony Trioxide Exacerbates the MAPK Signaling in Alveolar Bronchiolar Carcinomas in B6C3F1/N Mice. Toxicologic pathology 2023 Jan;51(1-2):39-55. Abstract Ton T, Hong H, Kovi R, Shockley K, Peddada S, Gerrish K, Janardhan K, Flake G, Stout M, Sills R, Pandiri A. Chronic Inhalation Exposure to Antimony Trioxide Exacerbates the MAPK Signaling in Alveolar Bronchiolar Carcinomas in B6C3F1/N Mice. Toxicologic pathology. 2023 Jan NTP Reports National Toxicology Program. Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones. National Toxicology Program technical report series 2018 Nov [Epub ahead of print]. Abstract National Toxicology Program. Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones. National Toxicology Program technical report series. 2018 Nov National Toxicology Program. Toxicology and carcinogenesis studies in B6C3F1/N mice exposed to whole-body radio frequency radiation at a frequency (1,900 MHz) and modulations (GSM and CDMA) used by cell phones. National Toxicology Program technical report series 2018 Nov [Epub ahead of print]. Abstract National Toxicology Program. Toxicology and carcinogenesis studies in B6C3F1/N mice exposed to whole-body radio frequency radiation at a frequency (1,900 MHz) and modulations (GSM and CDMA) used by cell phones. National Toxicology Program technical report series. 2018 Nov More Recent Publications from PubMed Back to Top Last Reviewed: December 29, 2025