Frederick Parham, Ph.D. | National Institute of Environmental Health Sciences
Source: https://www.niehs.nih.gov/research/atniehs/labs/ptb/staff/parham
Archived: 2026-04-23 17:20
Frederick Parham, Ph.D. | National Institute of Environmental Health Sciences
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Frederick Parham, Ph.D.
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Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Visit the NTP Website
Toxicoinformatics Group
Frederick M. Parham, Ph.D.
Mathematical Statistician
Tel 984-287-3169
[email protected]
Fred Parham, Ph.D., is a mathematical statistician in the Toxicoinformatics Group within the Predictive Toxicology Branch of the Division of Translational Toxicology. He came to the Branch in the summer of 2010 after spending several years working in the Environmental Systems Biology group of the NIEHS Division of Intramural Research. He is currently working on various projects involving the analysis and interpretation of high throughput screening data. He received his B. S. in mathematics from Duke University in 1984 and his Ph. D. from Princeton University in 1989.
ER AR1 18-M167, Mixture of AR- and ER-active chemicals
Recent Publications
Pelch K, Wignall J, Goldstone A, Ross P, Blain R, Shapiro A, Holmgren S, Hsieh J, Svoboda D, Auerbach S, Parham F, Masten S, Walker V, Rooney A, Thayer K. A scoping review of the health and toxicological activity of bisphenol A (BPA) structural analogues and functional alternatives.
Toxicology
.
2019 Aug 01;424:152235.
[
Abstract
Pelch K, Wignall J, Goldstone A, Ross P, Blain R, Shapiro A, Holmgren S, Hsieh J, Svoboda D, Auerbach S, Parham F, Masten S, Walker V, Rooney A, Thayer K. A scoping review of the health and toxicological activity of bisphenol A (BPA) structural analogues and functional alternatives. Toxicology. 2019 Aug 01
]
Pelch K, Wignall J, Goldstone A, Ross P, Blain R, Shapiro A, Holmgren S, Hsieh J, Svoboda D, Auerbach S, Parham F, Masten S, Thayer K. NTP Research Report on Biological Activity of Bisphenol A (BPA) Structural Analogues and Functional Alternatives: Research Report 4
NTP Research Reports
.
2017 Oct [Epub ahead of print].
[
Abstract
Pelch K, Wignall J, Goldstone A, Ross P, Blain R, Shapiro A, Holmgren S, Hsieh J, Svoboda D, Auerbach S, Parham F, Masten S, Thayer K. NTP Research Report on Biological Activity of Bisphenol A (BPA) Structural Analogues and Functional Alternatives: Research Report 4 NTP Research Reports. 2017 Oct
]
Thomas R, Gohlke J, Stopper G, Parham F, Portier C. Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure.
Genome biology
.
2009;10(4):R44.
[
Abstract
Thomas R, Gohlke J, Stopper G, Parham F, Portier C. Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure. Genome biology. 2009
]
Gohlke J, Armant O, Parham F, Smith M, Zimmer C, Castro D, Nguyen L, Parker J, Gradwohl G, Portier C, Guillemot F. Characterization of the proneural gene regulatory network during mouse telencephalon development.
BMC biology
.
2008 Mar 31;6:15.
[
Abstract
Gohlke J, Armant O, Parham F, Smith M, Zimmer C, Castro D, Nguyen L, Parker J, Gradwohl G, Portier C, Guillemot F. Characterization of the proneural gene regulatory network during mouse telencephalon development. BMC biology. 2008 Mar 31
]
Toyoshiba H, Sone H, Yamanaka T, Parham F, Irwin R, Boorman G, Portier C. Gene interaction network analysis suggests differences between high and low doses of acetaminophen.
Toxicology and applied pharmacology
.
2006 Sep 15;215(3):306-16.
[
Abstract
Toyoshiba H, Sone H, Yamanaka T, Parham F, Irwin R, Boorman G, Portier C. Gene interaction network analysis suggests differences between high and low doses of acetaminophen. Toxicology and applied pharmacology. 2006 Sep 15
]
NTP Reports
National Toxicology Program. Toxicology and carcinogenesis studies of di(2-ethylhexyl) phthalate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats.
National Toxicology Program technical report series
.
2021 Dec [Epub ahead of print].
[
Abstract
National Toxicology Program. Toxicology and carcinogenesis studies of di(2-ethylhexyl) phthalate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats. National Toxicology Program technical report series. 2021 Dec
]
More Recent Publications from PubMed
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to Top
Last Reviewed: December 19, 2025
Skip Navigation
Frederick Parham, Ph.D.
Close the left navigation
Add
Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.
Visit the NTP Website
Toxicoinformatics Group
Frederick M. Parham, Ph.D.
Mathematical Statistician
Tel 984-287-3169
[email protected]
Fred Parham, Ph.D., is a mathematical statistician in the Toxicoinformatics Group within the Predictive Toxicology Branch of the Division of Translational Toxicology. He came to the Branch in the summer of 2010 after spending several years working in the Environmental Systems Biology group of the NIEHS Division of Intramural Research. He is currently working on various projects involving the analysis and interpretation of high throughput screening data. He received his B. S. in mathematics from Duke University in 1984 and his Ph. D. from Princeton University in 1989.
ER AR1 18-M167, Mixture of AR- and ER-active chemicals
Recent Publications
Pelch K, Wignall J, Goldstone A, Ross P, Blain R, Shapiro A, Holmgren S, Hsieh J, Svoboda D, Auerbach S, Parham F, Masten S, Walker V, Rooney A, Thayer K. A scoping review of the health and toxicological activity of bisphenol A (BPA) structural analogues and functional alternatives.
Toxicology
.
2019 Aug 01;424:152235.
[
Abstract
Pelch K, Wignall J, Goldstone A, Ross P, Blain R, Shapiro A, Holmgren S, Hsieh J, Svoboda D, Auerbach S, Parham F, Masten S, Walker V, Rooney A, Thayer K. A scoping review of the health and toxicological activity of bisphenol A (BPA) structural analogues and functional alternatives. Toxicology. 2019 Aug 01
]
Pelch K, Wignall J, Goldstone A, Ross P, Blain R, Shapiro A, Holmgren S, Hsieh J, Svoboda D, Auerbach S, Parham F, Masten S, Thayer K. NTP Research Report on Biological Activity of Bisphenol A (BPA) Structural Analogues and Functional Alternatives: Research Report 4
NTP Research Reports
.
2017 Oct [Epub ahead of print].
[
Abstract
Pelch K, Wignall J, Goldstone A, Ross P, Blain R, Shapiro A, Holmgren S, Hsieh J, Svoboda D, Auerbach S, Parham F, Masten S, Thayer K. NTP Research Report on Biological Activity of Bisphenol A (BPA) Structural Analogues and Functional Alternatives: Research Report 4 NTP Research Reports. 2017 Oct
]
Thomas R, Gohlke J, Stopper G, Parham F, Portier C. Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure.
Genome biology
.
2009;10(4):R44.
[
Abstract
Thomas R, Gohlke J, Stopper G, Parham F, Portier C. Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure. Genome biology. 2009
]
Gohlke J, Armant O, Parham F, Smith M, Zimmer C, Castro D, Nguyen L, Parker J, Gradwohl G, Portier C, Guillemot F. Characterization of the proneural gene regulatory network during mouse telencephalon development.
BMC biology
.
2008 Mar 31;6:15.
[
Abstract
Gohlke J, Armant O, Parham F, Smith M, Zimmer C, Castro D, Nguyen L, Parker J, Gradwohl G, Portier C, Guillemot F. Characterization of the proneural gene regulatory network during mouse telencephalon development. BMC biology. 2008 Mar 31
]
Toyoshiba H, Sone H, Yamanaka T, Parham F, Irwin R, Boorman G, Portier C. Gene interaction network analysis suggests differences between high and low doses of acetaminophen.
Toxicology and applied pharmacology
.
2006 Sep 15;215(3):306-16.
[
Abstract
Toyoshiba H, Sone H, Yamanaka T, Parham F, Irwin R, Boorman G, Portier C. Gene interaction network analysis suggests differences between high and low doses of acetaminophen. Toxicology and applied pharmacology. 2006 Sep 15
]
NTP Reports
National Toxicology Program. Toxicology and carcinogenesis studies of di(2-ethylhexyl) phthalate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats.
National Toxicology Program technical report series
.
2021 Dec [Epub ahead of print].
[
Abstract
National Toxicology Program. Toxicology and carcinogenesis studies of di(2-ethylhexyl) phthalate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats. National Toxicology Program technical report series. 2021 Dec
]
More Recent Publications from PubMed
Back
to Top
Last Reviewed: December 19, 2025