R code for fitting Random Periods Model | National Institute of Environmental Health Sciences

R code for fitting Random Periods Model | National Institute of Environmental Health Sciences
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R code for fitting Random Periods Model
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R code for fitting Random Periods Model - Software Usage Agreement and Download
Developed by:
Shyamal D. Peddada
National Institute of Environmental Health Sciences
Biostatistics & Computational Biology Branch
Programmed by Mr. Sai Cheemalapati, Summer Intern 2011, Panther Creek High School
Purpose
You may use this R code for fitting the Random Periods Model (RPM) for cell cycle genes. Since outliers and influential observations are not uncommon, the parameters of RPM are estimated using the L_1 norm. The RPM is a nonlinear model that can be used to model the expression of a cell-cycle gene over time. For details regarding the model one may refer to Liu et al. (2004).
Software info
Details on how to use is provided in the
How to Use R code for Fitting Random Periods Model
webpage.
References
Liu D, Umbach D, Peddada SD, Li L, Crockett P and Weinberg C (2004). A Random-Periods Model for Expression of Cell-Cycle Genes. Proceedings of National Academy of Sciences, 101, No. 19, 7240-7245.
Download
CCOptimF.R
(2KB)
Contact
Clarice R. Weinberg, Ph.D.
Principal Investigator
Tel 984-287-3697
[email protected]
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Last Reviewed: March 30, 2026