Jui-Hua Hsieh, Ph.D. | National Institute of Environmental Health Sciences Skip Navigation Jui-Hua Hsieh, Ph.D. Close the left navigation Add Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS. Visit the NTP Website Toxicoinformatics Group Jui-Hua Hsieh, Ph.D. Staff Scientist Tel 984-287-3142 [email protected] Jui-Hua Hsieh, Ph.D., is a Staff Scientist in the Predictive Toxicology Branch of the Division of Translational Toxicology (DTT). Her primary roles involve method development and applications on concentration-response data, web application development for data visualization, and model development for prioritizing and predicting potential human toxicants. Prior to joining the DTT in 2011, she received her B.S. degree in Pharmacy from National Taiwan University and her Ph.D. degree in Pharmaceutical Sciences from University of North Carolina at Chapel Hill. Her Ph.D. work involves the development and application of cheminformatics tools for drug discovery projects, particularly hit identification in virtual screening. Recent Publications Tseng H, Wu Y, Chen Y, Lin T, Fang-Chin Y, Wu Y, Sung T, Yen S, Hsieh J, Hsu K, Pan S. Identification and biological evaluation of benzimidazole-based compounds as novel TGFβR1 inhibitors. Journal of enzyme inhibition and medicinal chemistry 2026 Dec;41(1):2600746. Abstract Tseng H, Wu Y, Chen Y, Lin T, Fang-Chin Y, Wu Y, Sung T, Yen S, Hsieh J, Hsu K, Pan S. Identification and biological evaluation of benzimidazole-based compounds as novel TGFβR1 inhibitors. Journal of enzyme inhibition and medicinal chemistry. 2026 Dec Ngan D, Ye L, Hsieh J, Xu T, Zhao J, Sakamuru S, Tao D, LeClair C, Zhao T, Rossoshek A, Reif D, Simeonov A, Xia M, Huang R. Impact of Chemical Quality on High-Throughput in Vitro Assays: A Tox21 Study. Chemical research in toxicology 2026 Apr 20;39(4):624-635. Abstract Ngan D, Ye L, Hsieh J, Xu T, Zhao J, Sakamuru S, Tao D, LeClair C, Zhao T, Rossoshek A, Reif D, Simeonov A, Xia M, Huang R. Impact of Chemical Quality on High-Throughput in Vitro Assays: A Tox21 Study. Chemical research in toxicology. 2026 Apr 20 Wu Y, Yang C, Lin T, Yeh Y, Fang-Chin Y, Sung T, Yen S, Hsieh J, Chung C, Pan S, Hsu K. Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment. Journal of chemical information and modeling 2026 Jan 12;66(1):577-590. Abstract Wu Y, Yang C, Lin T, Yeh Y, Fang-Chin Y, Sung T, Yen S, Hsieh J, Chung C, Pan S, Hsu K. Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment. Journal of chemical information and modeling. 2026 Jan 12 Konrad K, Allen-Moyer K, Ellis L, Hessel E, Jaka O, Muriana A, Martínez B, Del Pozo A, Schiavone V, Di Donato V, Sanz C, Truong L, Tanguay R, Shockley K, Ryan K, Hsieh J. Power calculations for larval zebrafish in light-dark transition test for developmental neurotoxicity. Neurotoxicology 2026 Jan;112:103371. Abstract Konrad K, Allen-Moyer K, Ellis L, Hessel E, Jaka O, Muriana A, Martínez B, Del Pozo A, Schiavone V, Di Donato V, Sanz C, Truong L, Tanguay R, Shockley K, Ryan K, Hsieh J. Power calculations for larval zebrafish in light-dark transition test for developmental neurotoxicity. Neurotoxicology. 2026 Jan Yang C, Lin T, Hsieh J, Hsu K, Chiueh P. Establishment of an Integrated Model for Predicting Compound Mutagenicity with a Feature Importance Analysis. Journal of chemical information and modeling 2025 Nov 10;65(21):11558-11571. Abstract Yang C, Lin T, Hsieh J, Hsu K, Chiueh P. Establishment of an Integrated Model for Predicting Compound Mutagenicity with a Feature Importance Analysis. Journal of chemical information and modeling. 2025 Nov 10 NTP Reports National Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series 2023 Jun [Epub ahead of print]. Abstract National Toxicology Program. Toxicology and carcinogenesis studies of an isomeric mixture of tris(chloropropyl) phosphate administered in feed to Sprague Dawley (Hsd:Sprague Dawley SD) rats and B6C3F1/N mice. National Toxicology Program technical report series. 2023 Jun More Recent Publications from PubMed Related Links Computational toxicology featured in special journal issue - Environmental Factor, March 2021 Back to Top Last Reviewed: December 19, 2025