AI Artificial Intelligence for S... | U.S. DOE Office of Science(SC)
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Artificial Intelligence for Science
Of Note
The White House Office of Technology Policy, National Science Foundation and Department of Energy announce over $1 billion in awards for Artificial Intelligence Institutes and Quantum Information Science Research Centers.
DOE Press Release
National Quantum Initiative Website
From internet search engines to autonomous vehicles, artificial intelligence (AI)—once mostly the stuff of science fiction—is becoming an increasingly familiar and practical feature of everyday life.
Two factors are driving interest in AI across the globe: the vast accumulation of data in our increasingly digitized society, and the growing capability and speed of today’s fastest computers for processing that data.
AI, including machine learning (ML), is an ideal tool for deriving new insights from analysis of very large data sets. AI becomes more useful as the speed and computational power of today’s supercomputers grows.
DOE stewards some of the fastest computers in the country. These high-performance computers along with the Exascale Computing Program will help build the hardware and software needed to develop and power the future generations of AI. In addition, vast data sets are generated at SC experimental user facilities – including data for high energy, nuclear and plasma physics, characterization of matter with x-rays and neutrons, and the genomic analysis for bioenergy.
To maximize the impact of data, DOE supports development of new methods and algorithms that increase the reliability (for what type and quantity of data do we expect results), robustness (how might slightly different data change the results), and rigor (have the assumptions and underlying theories been defined and validated) of machine learning algorithm and methods to support their use in scientific research. Individual research programs focus on enhancing the analysis of the data for their disciplines to maximize the scientific impact of data.
The Office of Science has a unique combination of capabilities to lead the nation in AI and ML research and development (R&D) for science:
A broad mission that presents new and unique research problems on a national and global scale that can use data science for innovations in fundamental science and energy research
Sources of massive and/or complex science and engineering data from sensors, instruments, SC’s national user facilities, and large-scale simulations
World-class high-performance computing (HPC) infrastructure, capable of world-leading AI research
World-class high-performance network infrastructure capable of integrating computing resources and data assets
An exceptional workforce with large numbers of domain scientists, computer scientists, and mathematicians currently engaged in AI and related fields.
Latest Topical Funding Opportunity Awards
Department of Energy Announces $78.8 Million for Scientific Discovery through Advanced Computing (SciDAC) Institutes
Award Selection:
December 2025
Announcement Number:
LAB 25-3510
Department of Energy Announces $16.6 Million for Research on Artificial Intelligence and Machine Learning Applied to Nuclear Science and Technology
Award Selection:
December 2025
Announcement Number:
DE-FOA-0003458
Department of Energy Announces $87 Million for AI investments
Award Selection:
December 2025
Announcement Number:
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