PFAS Exposure Linked to Reduced Fertility in Women | National Institute of Environmental Health Sciences

PFAS Exposure Linked to Reduced Fertility in Women | National Institute of Environmental Health Sciences
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PFAS Exposure Linked to Reduced Fertility in Women
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June 29, 2023
Exposure to per- and polyfluoroalkyl substances (PFAS) may reduce fertility in women by as much as 40%, researchers from the
NIEHS-funded Environmental Health Sciences Core Center at Mount Sinai
found. The team
reported
that higher levels of PFAS in blood were associated with a significant reduction in the likelihood of pregnancy and live birth among a group of reproductive-age women in Singapore who were trying to conceive.
“PFAS can disrupt our reproductive hormones and have been linked with delayed puberty onset and increased risks for endometriosis and polycystic ovary syndrome in previous studies. What our study adds is that PFAS may also decrease fertility in women who are generally healthy and are naturally trying to conceive,”
said senior author
and Mount Sinani Core Center member Damaskini Valvi, M.D., Ph.D.
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Last Reviewed: January 05, 2026