Small Business Innovation Research & Small Business Technology Transfer Grants (SBIR/STTR, R41, R42, R43, R44) | National Institute of Environmental Health Sciences
Skip Navigation
Small Business Innovation Research & Small Business Technology Transfer Grants (SBIR/STTR, R41, R42, R43, R44)
Close the left navigation
Program Lead
Lingamanaidu V. Ravichandran, Ph.D.
Health Scientist Administrator
Tel 984-287-3309
[email protected]
General Information on SBIR/STTR Grants
SBIR/STTR Funding Opportunities for Water Nanotechnologies Webinar
Thursday, August 25, 2022 • 1:00 – 2:30 p.m.
Webinar Archive
The webinar was co-hosted by the U.S. Environmental Protection Agency (EPA) and the
National Nanotechnology Initiative (NNI)
. Representatives from the EPA,
NIEHS
, the National Oceanic and Atmospheric Administration (NOAA), and the National Science Foundation (NSF) provided an overview of their current and upcoming SBIR/STTR funding opportunities for water nanotechnologies. The agencies' presentations were followed by a Q&A session.
Town Hall Recording
NIEHS hosted a SBIR/STTR Town Hall meeting on “Development of New Approach Methodologies to Reduce Animal Use in Toxicity Testing” on April 17, 2020 with presentations from NICEATM, EPA, FDA, DoD, 3M Corporation, Syngenta and Novartis.
The slides and presentations are available at
SBIR/STTR Town Hall Meeting on NAMs
Connect With Us
Register for the
SBIR-NIEHS LISTSERV
to receive program updates and announcements.
Follow us on X:
@NIEHS
Can't find what you are looking for?
email us
NIEHS Top 10 Resources for SBIR/STTR Applicants
Program Description
NIEHS SBIR/STTR grants help small businesses develop innovative and commercially viable products or technologies to translate and communicate environmental health research to improve public health. The SBIR/STTR program uses a combination of research, technology transfer, and communication strategies to aid the mission of NIEHS. Research and training areas include:
Exposure assessment tools such as sensors and computational tools and methods
Tools for evaluating environmental health and safety of engineered nanomaterials
Bio-monitoring technologies and biological response markers of exposure and response
Assays and model systems for screening compounds for toxicity
Intervention technologies to prevent or reduce exposures to environmental stressors
Educational materials to support understanding of environmental health science
To support understanding of environmental science
Superfund Research Program
- Detection and remediation technologies for contaminated sites
NIEHS Worker Training Program
- Advanced Training Technology (ATT) products for the health and safety training of hazardous materials (HAZMAT) workers, emergency responders, and skilled support personnel
For NIEHS budget guidelines and contacts see pages 30-31 of the
SBIR/STTR NIH, CDC, and FDA Program Descriptions and Research Topics
document.
Grant applications are accepted in response to the NIH Omnibus solicitation using the
Annotated SF424 (R&R) SBIR/STTR Form Set
(FORMS-I) and use the
SF424 (R&R) SBIR/STTR application guide
(Version I) for step-by-step instruction on how to complete the application. Be mindful that the
electronic submission process
for HHS SBIR and STTR grants is multi-step, and can take six to eight weeks to complete the five registrations required prior to submission.
NIEHS Participating HHS SBIR and STTR Omnibus Solicitations
PA-24-245
- PHS 2024-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
PA-24-246
- PHS 2024-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
PA-24-247
- PHS 2024-2 Omnibus Solicitation of the NIH for Small Business 3Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
PA-24-248
- PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
SBIR/STTR Application Types Accepted by NIEHS
For
PA-24-245
- Parent SBIR [R43/R44] Clinical Trial Not Allowed and
PA-24-246
- Parent SBIR [R43/R44] Clinical Trial Required – Phase I, Phase II, Fast-Track, and Direct to Phase II.
For
PA-24-247
- Parent STTR [R41/R42] Clinical Trial Not Allowed and
PA-24-248
- Parent STTR [R41/R42] Clinical Trial Required - Phase I, Phase II, and Fast-Track. Direct Phase II NOT Allowed.
Annual SBIR/STTR Application Receipt Dates
January 5, 2025
April 5, 2025
September 5, 2025
Other NIEHS Specific/Participating Request for Applications and Program Announcements
SBIR/STTR Commercialization Readiness Program (
SB1
PAR-23-219
- SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)
Standard receipt dates until September 5, 2025
General SBIR/STTR Information
NIH SBIR/STTR FAQs
Frequently asked questions applicable to all NIH SBIR/STTR applications and grants
SBIR/STTR Application Process Infographic
Step-by-step application process visual
NIH SBIR/STTR Programs
Description, eligibility, and associated NIH institutes
NIH SBIR/STTR Omnibus Funding
Description, and links to omnibus related topics
NIEHS Small Business Programs
General overview of NIEHS areas of interest
Small Business Grants Homepage
General information about SBIR and STTR grants
Hazardous Substances Remediation and Site Characterization SBIR Program
The NIEHS Superfund Research Program (SRP) "Hazardous Substances Remediation and Detection Program" supports Small Business Innovation Research Grants (SBIR R43, R44) to foster the commercialization of novel, cost-competitive technologies, products, and devices for remediation and detection of hazardous substances in the environment
Grant Tools and Strategies
Resources from NIAID including sample applications and summary statements
Additional Contacts
The contact for the
Superfund SBIR program
is:
Heather F. Henry, Ph.D.
Health Scientist Administrator, Superfund Research Program
Tel 984-287-3268
[email protected]
The contact for the
Worker Training SBIR program
is:
Eric Persaud, Dr. P.H.
Health Specialist
Tel 202-993-6256
[email protected]
Related Links
Air quality monitoring innovations merit small business recognition
- Environmental Factor, February 2021 - Environmental Factor, February 2021
Multiple NIEHS-supported SBIR/STTR success stories highlighted on the NIH SBIR website
NIH Grants Policy Statement
Back
to Top
Last Reviewed: March 19, 2026