Mayo Clinic in Rochester, Minnesota - Mayo Clinic Patient & Visitor Guide Mayo Clinic in Minnesota Mayo Clinic in Rochester, Minnesota World-class care, focused on you Request an appointment Welcome to Mayo Clinic in Rochester, Minnesota, the original and largest Mayo Clinic campus. Located in the heart of Rochester, Minnesota — a dynamic city just 90 minutes south of the Twin Cities of Minneapolis and St. Paul — Mayo Clinic has been safely caring for patients from around the world for more than 100 years. Mayo Clinic will always be your safe care destination. Planning your trip here Rochester construction updates Getting here Travel help & guidance Concierge services Your packing list Campus maps & help getting around Accessibility (mobility, visual and hearing help) Parking Hotels & lodging Places to eat International services Visiting Mayo Clinic discussion board Support groups Social work Spiritual and religious services Clinical Ethics Consultation Service Interpreter services Patient education Humanities in Medicine Additional help to make the most of your visit Billing & Insurance Cost Estimator Charitable Care & Financial Assistance Medical images & records request Pharmacy Medical supplies & equipment Gift shops & online bookstore Optical store Patient appointment and visitor updates Learn about Rochester, Minnesota Discover more about this Midwest destination. Experience Rochester MN Wellness services to enhance your onsite experience We offer a variety of wellness services including spa services, healthy living classes, and more to help make your stay both comfortable and enjoyable. Rejuvenate spa services All wellness services Be a blood donor Each whole blood donation can help save lives. Learn more about the Blood Donor Program There’s still time! Triple My Impact Hurry to 3X your gift’s impact on cancer research and care! Triple My Impact