Selected Publications | National Institute of Environmental Health Sciences

Selected Publications | National Institute of Environmental Health Sciences
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Calcium Signaling in Health & Disease Group
Kar P, Barak P, Zerio A, Lin YP, Parekh AJ, Watts VJ, Cooper DMF, Zaccolo M, Kramer H, Parekh AB. 2021. AKAP79 orchestrates a cyclic amp signalosome adjacent to orai1 Ca2+ channels.
Function
2(5):zqab036. [
Abstract
Kar P, Barak P, Zerio A, Lin YP, Parekh AJ, Watts VJ, Cooper DMF, Zaccolo M, Kramer H, Parekh AB. 2021. AKAP79 orchestrates a cyclic amp signalosome adjacent to orai1 Ca2+ channels. Function 2(5):zqab036.
] [
Full Text
Kar P, Barak P, Zerio A, Lin YP, Parekh AJ, Watts VJ, Cooper DMF, Zaccolo M, Kramer H, Parekh AB. 2021. AKAP79 orchestrates a cyclic amp signalosome adjacent to orai1 Ca2+ channels. Function 2(5):zqab036.
]
Kar P, Lin YP, Bhardwaj R, Tucker CJ, Bird GS, Hediger MA, Monico C, Amin N, Parekh AB. 2021. The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca 2+ entry.
Proc Natl Acad Sci USA.
118(19):e2012908118. [
Abstract
Kar P, Lin YP, Bhardwaj R, Tucker CJ, Bird GS, Hediger MA, Monico C, Amin N, Parekh AB. 2021. The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca 2+ entry. Proc Natl Acad Sci USA. 118(19):e2012908118.
]
Lin YP, Bakowski D, Mirams GR, Parekh AB. 2019. Selective recruitment of different Ca
2+
-dependent transcription factors by STIM1-Orai1 channel clusters.
Nature Communications.
10(1):2516. [
Abstract
Lin YP, Bakowski D, Mirams GR, Parekh AB. 2019. Selective recruitment of different Ca
2+
-dependent transcription factors by STIM1-Orai1 channel clusters. Nature Communications. 10(1):2516.
]
Lin YP, Nelson C, Kramer H, Parekh AB. 2018. The allergen Der p3 from house dust mite stimulates store-operated Ca
2+
channels and mast cell migration through PAR4 receptors.
Molecular Cell.
70(2):228-241.e5. [
Abstract
Lin YP, Nelson C, Kramer H, Parekh AB. 2018. The allergen Der p3 from house dust mite stimulates store-operated Ca
2+
channels and mast cell migration through PAR4 receptors. Molecular Cell. 70(2):228-241.e5.
]
Samanta K, Mirams GR, Parekh AB. 2018. Sequential forward and reverse transport of the Na
+
Ca
2+
exchanger generates Ca2+ oscillations within mitochondria.
Nature Communications
. 9(1):156. [
Abstract
Samanta K, Mirams GR, Parekh AB. 2018. Sequential forward and reverse transport of the Na
+
Ca
2+
exchanger generates Ca2+ oscillations within mitochondria. Nature Communications. 9(1):156.
]
.
Kar P, Mirams GR, Christian HC, Parekh AB. 2016. Control of NFAT isoform activation and NFAT-dependent gene expression through two coincident and spatially segregated intracellular Ca
2+
signals.
Molecular Cell.
64(4):746-759. [
Abstract
Kar P, Mirams GR, Christian HC, Parekh AB. 2016. Control of NFAT isoform activation and NFAT-dependent gene expression through two coincident and spatially segregated intracellular Ca
2+
signals. Molecular Cell. 64(4):746-759.
]
Kar P, Parekh AB. 2015. Distinct spatial Ca
2+
signatures selectively activate different NFAT transcription factor isoforms.
Molecular Cell
. 58(2):232-243. [
Abstract
Kar P, Parekh AB. 2015. Distinct spatial Ca
2+
signatures selectively activate different NFAT transcription factor isoforms. Molecular Cell. 58(2):232-243.
]
Ng SW, Bakowski D, Nelson C, Mehta R, Almeyda R, Bates G, Parekh AB. 2012. Cysteinyl leukotriene type I receptor desensitization sustains Ca
2+
-dependent gene expression.
Nature.
482(7383):111-115. [
Abstract
Ng SW, Bakowski D, Nelson C, Mehta R, Almeyda R, Bates G, Parekh AB. 2012. Cysteinyl leukotriene type I receptor desensitization sustains Ca
2+
-dependent gene expression. Nature. 482(7383):111-115.
]
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Last Reviewed: April 14, 2026