Techniques in Toxicologic Pathology | National Institute of Environmental Health Sciences

Techniques in Toxicologic Pathology | National Institute of Environmental Health Sciences
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Techniques in Toxicologic Pathology
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Global Toxicologic Pathology Training Program
Immunohistochemistry
Immunohistochemistry in Investigative and Toxicologic Pathology
: This article provides an overview of technical aspects of immunohistochemistry. It offers guidance on antibody selection and method optimization and discusses variables that can affect results, interpretation, and reproducibility. (Last reviewed January 2022)
NIEHS Immunohistochemistry protocols
features protocols for numerous markers.
Laser Capture Microdissection
This NIEHS website offers
guidance on tissue preparation, microdissection, and staining
.
RNA Extraction
This NIEHS website offers
guidance on high quality RNA extraction
for use in gene expression and microarray analysis.
Vaginal Cytology
Vaginal Cytology of the Laboratory Rat and Mouse
: This review offers detailed descriptions and illustrations of vaginal cytology of the rat and mouse estrous cycle. (Last reviewed January 2022)
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Last Reviewed: January 06, 2026