Selected Publications | National Institute of Environmental Health Sciences
Source: https://www.niehs.nih.gov/research/atniehs/labs/mcbl/molecular/publications
Archived: 2026-04-23 17:11
Selected Publications | National Institute of Environmental Health Sciences
Skip Navigation
Selected Publications
Close the left navigation
Add
Molecular Endocrinology Group
Bortner CD, Cidlowski JA. 2020. Ions, the Movement of Water and the Apoptotic Volume Decrease.
Front Cell Dev Biol
; doi: 10.3389/fcell.2020.611211 [Online 25 November 2020]. [
Abstract
Bortner CD, Cidlowski JA. 2020. Ions, the Movement of Water and the Apoptotic Volume Decrease. Front Cell Dev Biol; doi: 10.3389/fcell.2020.611211 [Online 25 November 2020].
]
Perez Kerkvliet C, Dwyer AR, Diep CH, Oakley RH, Liddle C, Cidlowski JA, Lange CA. 2020. Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer.
Breast Cancer Res
; doi: 10.1186/s13058-020-01277-8 [Online 1 May 2020]. [
Abstract
Perez Kerkvliet C, Dwyer AR, Diep CH, Oakley RH, Liddle C, Cidlowski JA, Lange CA. 2020. Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer. Breast Cancer Res; doi: 10.1186/s13058-020-01277-8 [Online 1 May 2020].
]
Cain DW, Cidlowski JA. 2020. After 62 years of regulating immunity, dexamethasone meets COVID-19.
Nat Rev Immunol
20(10):587-588. [
Abstract
Cain DW, Cidlowski JA. 2020. After 62 years of regulating immunity, dexamethasone meets COVID-19. Nat Rev Immunol 20(10):587-588.
]
Patt M, Gysi J, Faresse N, Cidlowski JA, Odermatt A. 2020. Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211.
Mol Cell Endocrinol
; doi: 10.1016/j.mce.2020.110873 [Online 22 June 2020]. [
Abstract
Patt M, Gysi J, Faresse N, Cidlowski JA, Odermatt A. 2020. Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211. Mol Cell Endocrinol; doi: 10.1016/j.mce.2020.110873 [Online 22 June 2020].
]
Cruz-Topete D, Oakley RH, Cidlowski JA. 2020. Glucocorticoid Signaling and the Aging Heart. Front Endocrinol (Lausanne); doi: 10.3389/fendo.2020.00347 [Online 27 May 2020]. [
Abstract
Cruz-Topete D, Oakley RH, Cidlowski JA. 2020. Glucocorticoid Signaling and the Aging Heart. Front Endocrinol (Lausanne); doi: 10.3389/fendo.2020.00347 [Online 27 May 2020].
]
Diaz-Jimenez David, Petrillo Maria Grazia, Busada Jonathan, Hermoso Marcela A., Cidlowski John A. 2020. Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4.
J Biol Chem
; doi: 10.1074/jbc.RA119.010894 [Online 27 January 2020]. [
Abstract
Diaz-Jimenez David, Petrillo Maria Grazia, Busada Jonathan, Hermoso Marcela A., Cidlowski John A. 2020. Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4. J Biol Chem; doi: 10.1074/jbc.RA119.010894 [Online 27 January 2020].
]
Quinn MA, McCalla A, He B, Xu X, Cidlowski JA. Silencing of Maternal Hepatic Glucocorticoid Receptor Is Essential for Normal Fetal Development in Mice.
Communications Biology
2019 2:104. [
Abstract
Quinn MA, McCalla A, He B, Xu X, Cidlowski JA. Silencing of Maternal Hepatic Glucocorticoid Receptor Is Essential for Normal Fetal Development in Mice. Communications Biology 2019 2:104.
]
Cruz-Topete D, Oakley RH, Burford NG, Myers PH, Xu X, Cidlowski JA. Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure.
Journal of the American Heart Association
2019 8(15):e011012-. [
Abstract
Cruz-Topete D, Oakley RH, Burford NG, Myers PH, Xu X, Cidlowski JA. Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure. Journal of the American Heart Association 2019 8(15):e011012-.
]
Petrillo MG, Oakley RH, Cidlowski JA. Beta-Arrestin-1 inhibits glucocorticoid receptor turnover and alters glucocorticoid signaling.
The Journal of Biological Chemistry
2019 294(29):11225-11239. [
Abstract
Petrillo MG, Oakley RH, Cidlowski JA. Beta-Arrestin-1 inhibits glucocorticoid receptor turnover and alters glucocorticoid signaling. The Journal of Biological Chemistry 2019 294(29):11225-11239.
]
Busada JT, Ramamoorthy S, Cain DW, Xu X, Cook DN, Cidlowski JA. Endogenous Glucocorticoids Prevent Gastric Metaplasia by Suppressing Spontaneous Inflammation.
The Journal of Clinical Investigation
2019 129(3):1345-1358. [
Abstract
Busada JT, Ramamoorthy S, Cain DW, Xu X, Cook DN, Cidlowski JA. Endogenous Glucocorticoids Prevent Gastric Metaplasia by Suppressing Spontaneous Inflammation. The Journal of Clinical Investigation 2019 129(3):1345-1358.
]
Oakley RH, Busillo JM, Cidlowski JA. Cross-talk between the Glucocorticoid Receptor and MyoD Family Inhibitor Domain Containing Protein Provides a New Mechanism for Generating Tissue-Specific Responses to Glucocorticoids.
The Journal of biological chemistry
2017 292(14):5825-5844. [
Abstract
Oakley RH, Busillo JM, Cidlowski JA. Cross-talk between the Glucocorticoid Receptor and MyoD Family Inhibitor Domain Containing Protein Provides a New Mechanism for Generating Tissue-Specific Responses to Glucocorticoids. The Journal of biological chemistry 2017 292(14):5825-5844.
]
Whirledge S, Cidlowski JA. Glucocorticoids and Reproduction: Traffic Control on the Road to Reproduction.
Trends in Endocrinology and Metabolism
2017 28(6):399-415. [
Abstract
Whirledge S, Cidlowski JA. Glucocorticoids and Reproduction: Traffic Control on the Road to Reproduction. Trends in Endocrinology and Metabolism 2017 28(6):399-415.
]
Kadmiel M, Janoshazi A, Cidlowski JA. Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye.
Experimental Eye Research
2016
152()
:10-33. [
Abstract
Kadmiel M, Janoshazi A, Cidlowski JA. Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye. Experimental Eye Research 2016 152():10-33.
]
Cruz-Topete D, He B, Chang J, Xu X, Cidlowski JA. Krüppel-like Factor 13 Is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death.
The Journal of biological chemistry
2016 291(37):19374-19386. [
Abstract
Cruz-Topete D, He B, Chang J, Xu X, Cidlowski JA. Krüppel-like Factor 13 Is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death. The Journal of biological chemistry 2016 291(37):19374-19386.
]
Cruz-Topete, D, Myers, P, Foley, J , Willis, M, Cidlowski, J. Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice.
Endocrinology
2016 157(7):2759-2771. [
Abstract
Cruz-Topete, D, Myers, P, Foley, J , Willis, M, Cidlowski, J. Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice. Endocrinology 2016 157(7):2759-2771.
]
Quinn MA, Cidlowski JA. Endogenous hepatic glucocorticoid receptor signaling coordinates sex-biased inflammatory gene expression.
FASEB journal: official publication of the Federation of American Societies for Experimental Biology
2016 30(2):971-982. [
Abstract
Quinn MA, Cidlowski JA. Endogenous hepatic glucocorticoid receptor signaling coordinates sex-biased inflammatory gene expression. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 2016 30(2):971-982.
]
Bortner CD, Scoltock AB, Cain DW, Cidlowski JA. T-cell development of resistance to apoptosis is driven by a metabolic shift in carbon source and altered activation of death pathways.
Cell death and differentiation
2016
23(5)
:889-902. [
Abstract
Bortner CD, Scoltock AB, Cain DW, Cidlowski JA. T-cell development of resistance to apoptosis is driven by a metabolic shift in carbon source and altered activation of death pathways. Cell death and differentiation 2016 23(5):889-902.
]
He B, Cruz-Topete D, Oakley RH, Xiao X, Cidlowski JA. Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver.
Molecular and cellular biology
2015
36(5)
:714-730. [
Abstract
He B, Cruz-Topete D, Oakley RH, Xiao X, Cidlowski JA. Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver. Molecular and cellular biology 2015 36(5):714-730.
]
Whirledge SD, Oakley RH, Myers PH, Lydon JP, DeMayo F, Cidlowski JA. Uterine glucocorticoid receptors are critical for fertility in mice through control of embryo implantation and decidualization.
Proceedings of the National Academy of Sciences of the United States of America
2015 112(49):15166-15171. [
Abstract
Whirledge SD, Oakley RH, Myers PH, Lydon JP, DeMayo F, Cidlowski JA. Uterine glucocorticoid receptors are critical for fertility in mice through control of embryo implantation and decidualization. Proceedings of the National Academy of Sciences of the United States of America 2015 112(49):15166-15171.
]
Cruz-Topete D, Cidlowski JA. One hormone, two actions: anti- and pro-inflammatory effects of glucocorticoids.
Neuroimmunomodulation
2015
22(1-2)
:20-32. [
Abstract
Cruz-Topete D, Cidlowski JA. One hormone, two actions: anti- and pro-inflammatory effects of glucocorticoids. Neuroimmunomodulation 2015 22(1-2):20-32.
]
Bortner CD, Cidlowski JA. Ion channels and apoptosis in cancer.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
2014
369(1638)
:20130104-. [
Abstract
Bortner CD, Cidlowski JA. Ion channels and apoptosis in cancer. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2014 369(1638):20130104-.
]
Gruver-Yates AL, Quinn MA, Cidlowski JA. Analysis of glucocorticoid receptors and their apoptotic response to dexamethasone in male murine B cells during development.
Endocrinology
155(2)
:463-474, 2014. [
Abstract
Gruver-Yates AL, Quinn MA, Cidlowski JA. Analysis of glucocorticoid receptors and their apoptotic response to dexamethasone in male murine B cells during development. Endocrinology 155(2):463-474, 2014.
]
Franco R, Bortner CD, Schmitz I, Cidlowski JA. Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.
Apoptosis: an international journal on programmed cell death
19(1)
:117-134, 2014. [
Abstract
Franco R, Bortner CD, Schmitz I, Cidlowski JA. Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1. Apoptosis: an international journal on programmed cell death 19(1):117-134, 2014.
]
Kadmiel M, Cidlowski JA. Glucocorticoid Receptor Signaling in Health and Disease.
Trends in Pharmacological Sciences
2013 34(9):518-530. [
Abstract
Kadmiel M, Cidlowski JA. Glucocorticoid Receptor Signaling in Health and Disease. Trends in Pharmacological Sciences 2013 34(9):518-530.
]
Gruver-Yates AL, Cidlowski JA. Tissue-specific actions of glucocorticoids on apoptosis: a double-edged sword. Cells 2013 2(2):202-223. [
Abstract
Gruver-Yates AL, Cidlowski JA. Tissue-specific actions of glucocorticoids on apoptosis: a double-edged sword. Cells 2013 2(2):202-223.
]
Oakley RH, Cidlowski JA. The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease.
Journal of Allergy and Clinical Immunology
2013
132(5)
:1033-1044. [
Abstract
Oakley RH, Cidlowski JA. The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease. Journal of Allergy and Clinical Immunology 2013 132(5):1033-1044.
]
Whirledge S, Cidlowski JA. A role for glucocorticoids in stress-impaired reproduction: beyond the hypothalamus and pituitary.
Endocrinology
154(12)
:4450-4468, 2013. [
Abstract
Whirledge S, Cidlowski JA. A role for glucocorticoids in stress-impaired reproduction: beyond the hypothalamus and pituitary. Endocrinology 154(12):4450-4468, 2013.
]
Revollo JR, Oakley RH, Lu NZ, Kadmiel M, Gandhavadi M, Cidlowski JA. HES1 Is a Master Regulator of Glucocorticoid Receptor–Dependent Gene Expression.
Science Signaling
6(304)
:ra103-, 2013. [
Abstract
Revollo JR, Oakley RH, Lu NZ, Kadmiel M, Gandhavadi M, Cidlowski JA. HES1 Is a Master Regulator of Glucocorticoid Receptor–Dependent Gene Expression. Science Signaling 6(304):ra103-, 2013.
]
Whirledge S, Xu X, Cidlowski JA. Global gene expression analysis in human uterine epithelial cells defines new targets of glucocorticoid and estradiol antagonism.
Biology of Reproduction
89(3)
:66, 2013. [
Abstract
Whirledge S, Xu X, Cidlowski JA. Global gene expression analysis in human uterine epithelial cells defines new targets of glucocorticoid and estradiol antagonism. Biology of Reproduction 89(3):66, 2013.
]
Oakley RH, Ren R, Cruz-Topete D, Bird GS, Myers PH, Boyle MC, Schneider MD, Willis MS, Cidlowski JA. Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease.
Proceedings of the National Academy of Sciences of the United States of America
110(42)
:17035-40, 2013. [
Abstract
Oakley RH, Ren R, Cruz-Topete D, Bird GS, Myers PH, Boyle MC, Schneider MD, Willis MS, Cidlowski JA. Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease. Proceedings of the National Academy of Sciences of the United States of America 110(42):17035-40, 2013.
]
Oakley RH, Revollo J, Cidlowski JA. Glucocorticoids regulate arrestin gene expression and redirect the signaling profile of G protein-coupled receptors.
Proceedings of the National Academy of Sciences of the United States of America
109(43)
:17591-6, 2012. [
Abstract
Oakley RH, Revollo J, Cidlowski JA. Glucocorticoids regulate arrestin gene expression and redirect the signaling profile of G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America 109(43):17591-6, 2012.
]
Ren R, Oakley RH, Cruz-Topete D, Cidlowski JA. Dual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosis.
Endocrinology
153(11)
:5346-60, 2012. [
Abstract
Ren R, Oakley RH, Cruz-Topete D, Cidlowski JA. Dual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosis. Endocrinology 153(11):5346-60, 2012.
]
Jewell CM, Scoltock AB, Hamel BL, Yudt MR, Cidlowski JA. Complex human glucocorticoid receptor dim mutations define glucocorticoid induced apoptotic resistance in bone cells.
Endocrinology
26(2)
:244-56, 2012. [
Abstract
Jewell CM, Scoltock AB, Hamel BL, Yudt MR, Cidlowski JA. Complex human glucocorticoid receptor dim mutations define glucocorticoid induced apoptotic resistance in bone cells. Endocrinology 26(2):244-56, 2012.
]
Bortner CD, Scoltock AB, Sifre MI, Cidlowski JA. Osmotic stress resistance imparts acquired anti-apoptotic mechanisms in lymphocytes..
The Journal of biological chemistry
287(9)
:6284-95, 2012. [
Abstract
Bortner CD, Scoltock AB, Sifre MI, Cidlowski JA. Osmotic stress resistance imparts acquired anti-apoptotic mechanisms in lymphocytes.. The Journal of biological chemistry 287(9):6284-95, 2012.
]
Gross KL, Oakley RH, Scoltock AB, Jewel CM, Cidlowski JA. Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance.
Molecular Endocrinology
25(7)
:1087-1099, 2011. [
Abstract
Gross KL, Oakley RH, Scoltock AB, Jewel CM, Cidlowski JA. Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance. Molecular Endocrinology 25(7):1087-1099, 2011.
]
Busillo JM, Azzam KM, Cidlowski JA. Glucocorticoids sensitize the innate immune system through regulation of the NLRP3 inflammasome.
The Journal of biological chemistry
286(44)
:38703-13, 2011. [
Abstract
Busillo JM, Azzam KM, Cidlowski JA. Glucocorticoids sensitize the innate immune system through regulation of the NLRP3 inflammasome. The Journal of biological chemistry 286(44):38703-13, 2011.
]
Smith LK, Shah RR, Cidlowski JA. Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis.
The Journal of biological chemistry
285(47)
:36698-36708, 2010. [
Abstract
Smith LK, Shah RR, Cidlowski JA. Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis. The Journal of biological chemistry 285(47):36698-36708, 2010.
]
Ajiro K, Scoltock A , Smith LK, Ashasima M, Cidlowski JA. Reciprocal Epigenetic Modification of Histone H2B occurs in Chromatin during Apoptosis in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America
17(6)
:984-993, 2010. [
Abstract
Ajiro K, Scoltock A , Smith LK, Ashasima M, Cidlowski JA. Reciprocal Epigenetic Modification of Histone H2B occurs in Chromatin during Apoptosis in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America 17(6):984-993, 2010.
]
Gross KL, Lu NZ, Cidlowski JA. Molecular mechanisms regulating glucocorticoid sensitivity and resistance. Molecular and cellular endocrinology 2009 300(1-2):7-16. [
Abstract
Gross KL, Lu NZ, Cidlowski JA. Molecular mechanisms regulating glucocorticoid sensitivity and resistance. Molecular and cellular endocrinology 2009 300(1-2):7-16.
]
Ajiro K, Bortner CD, Westmoreland J, Cidlowski JA. 2008. An endogenous calcium-dependent, caspase-independent intranuclear degradation pathway in thymocyte nuclei: antagonism by physiological concentrations of K(+) ions.
Exp Cell Res
314(6)
:1237-1249. [
Abstract
Ajiro K, Bortner CD, Westmoreland J, Cidlowski JA. 2008. An endogenous calcium-dependent, caspase-independent intranuclear degradation pathway in thymocyte nuclei: antagonism by physiological concentrations of K(+) ions. Exp Cell Res 314(6):1237-1249.
]
Franco R, Dehaven WI, Sifre MI, Bortner CD, Cidlowski JA. Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis.
J Biol Chem
283(52)
:36071-36087, 2008. [
Abstract
Franco R, Dehaven WI, Sifre MI, Bortner CD, Cidlowski JA. Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis. J Biol Chem 283(52):36071-36087, 2008.
]
Galliher-Beckley AJ, Williams JG, Collins JB, Cidlowski JA. Glycogen synthase kinase 3beta-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles.
Molecular and cellular biology
28(24)
:7309-7322, 2008. [
Abstract
Galliher-Beckley AJ, Williams JG, Collins JB, Cidlowski JA. Glycogen synthase kinase 3beta-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles. Molecular and cellular biology 28(24):7309-7322, 2008.
]
Gross KL, Cidlowski JA. Tissue-specific glucocorticoid action: A family affair.
Trends in endocrinology and metabolism: TEM
19(9)
:331-339, 2008. [
Abstract
Gross KL, Cidlowski JA. Tissue-specific glucocorticoid action: A family affair. Trends in endocrinology and metabolism: TEM 19(9):331-339, 2008.
]
Bortner CD, Sifre MI, Cidlowski JA. Cationic gradient reversal and cytoskeleton-independent volume fegulatory pathways define an early stage of apoptosis.
The Journal of Biological Chemistry
283(11)
:7219-7229, 2008. [
Abstract
Bortner CD, Sifre MI, Cidlowski JA. Cationic gradient reversal and cytoskeleton-independent volume fegulatory pathways define an early stage of apoptosis. The Journal of Biological Chemistry 283(11):7219-7229, 2008.
]
Lu NZ, Collins JB, Grissom SF, Cidlowski JA. Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor.
Molecular and Cellular Biology
27(20)
:7143-7160, 2007. [
Abstract
Lu NZ, Collins JB, Grissom SF, Cidlowski JA. Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor. Molecular and Cellular Biology 27(20):7143-7160, 2007.
]
Franco R, Panayiotidis MI, Cidlowski JA. Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation.
Journal of Biological Chemistry
282(42)
:30452-30465, 2007. [
Abstract
Franco R, Panayiotidis MI, Cidlowski JA. Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation. Journal of Biological Chemistry 282(42):30452-30465, 2007.
]
Lewis-Tuffin LJ, Jewell CM, Bienstock RJ, Collins JB and Cidlowski JA. Human glucocorticoid receptor ? binds RU-486 and is transcriptionally active.
Molecular and Cellular Biology
p. 2266-2282
, Mar 2007. [
Abstract
Lewis-Tuffin LJ, Jewell CM, Bienstock RJ, Collins JB and Cidlowski JA. Human glucocorticoid receptor ? binds RU-486 and is transcriptionally active. Molecular and Cellular Biology p. 2266-2282, Mar 2007.
]
Lu NZ and Cidlowski JA. Glucocorticoid receptor isoforms generate transcription specificity.
Trends in Cell Biology
16(6):
301-307, 2006. [
Abstract
Lu NZ and Cidlowski JA. Glucocorticoid receptor isoforms generate transcription specificity. Trends in Cell Biology 16(6):301-307, 2006.
]
Franco R, Bortner CD and Cidlowski JA. Potential roles of electrogenic ion transport and plasma membrane depolarization in apoptosis.
J. of Membrane Biology
209
: 43-58, 2006. [
Abstract
Franco R, Bortner CD and Cidlowski JA. Potential roles of electrogenic ion transport and plasma membrane depolarization in apoptosis. J. of Membrane Biology 209: 43-58, 2006.
]
Franco R and Cidlowski JA. SLCO/OATP-like transport of glutathione in FasL-induced apoptosis.
Journal of Biological Chemistry
281
(40):29542-29557, 2006. [
Abstract
Franco R and Cidlowski JA. SLCO/OATP-like transport of glutathione in FasL-induced apoptosis. Journal of Biological Chemistry 281 (40):29542-29557, 2006.
]
Smoak K and Cidlowski JA. Glucocorticoids regulate tristetetraprolin synthesis and posttrancriptionally regulate tumor necrosis factor alpha inflammatory signaling.
Molecular and Celullar Biology
26(23):
9126-9135, 2006. [
Abstract
Smoak K and Cidlowski JA. Glucocorticoids regulate tristetetraprolin synthesis and posttrancriptionally regulate tumor necrosis factor alpha inflammatory signaling. Molecular and Celullar Biology 26(23):9126-9135, 2006.
]
G. Heimlich and Cidlowski JA. Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells.
J. Biol. Chem.
281:
2232-2241, 2006. [
Abstract
G. Heimlich and Cidlowski JA. Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells. J. Biol. Chem. 281: 2232-2241, 2006.
]
Schaaf MJM, Lewis-Tuffin LJ and Cidlowski JA. Ligand-Selective Targeting of the Glucocorticoid Receptor to Nuclear Subdomains is associated with Decreased Receptor Mobility.
Molecular Endocrinology
19(6)
: 1501-1515, 2005. [
Abstract
Schaaf MJM, Lewis-Tuffin LJ and Cidlowski JA. Ligand-Selective Targeting of the Glucocorticoid Receptor to Nuclear Subdomains is associated with Decreased Receptor Mobility. Molecular Endocrinology 19(6): 1501-1515, 2005.
]
Lu NZ and Cidlowski JA. Translational Regulatory Mechanisms Generate N-terminal Glucocorticoid Receptor Isoforms with Unique Transcriptional Target Genes.
Molecular Cell.
Vol.18,
331-342 April 29, 2005. [
Abstract
Lu NZ and Cidlowski JA. Translational Regulatory Mechanisms Generate N-terminal Glucocorticoid Receptor Isoforms with Unique Transcriptional Target Genes. Molecular Cell. Vol.18, 331-342 April 29, 2005.
]
Hermoso MA, Matsuguchi T, Smoak K and Cidlowski JA. Glucocorticoids and Tumor Necrosis Factor Alpha Cooperatively Regulate Toll-Like Receptor 2 Gene Expression.
Molecular and Cellular Biology,
p.
4743-4756
,
June 2004.
[
Abstract
Hermoso MA, Matsuguchi T, Smoak K and Cidlowski JA. Glucocorticoids and Tumor Necrosis Factor Alpha Cooperatively Regulate Toll-Like Receptor 2 Gene Expression. Molecular and Cellular Biology, p.4743-4756, June 2004.
]
Back
to Top
Last Reviewed: April 14, 2026
Skip Navigation
Selected Publications
Close the left navigation
Add
Molecular Endocrinology Group
Bortner CD, Cidlowski JA. 2020. Ions, the Movement of Water and the Apoptotic Volume Decrease.
Front Cell Dev Biol
; doi: 10.3389/fcell.2020.611211 [Online 25 November 2020]. [
Abstract
Bortner CD, Cidlowski JA. 2020. Ions, the Movement of Water and the Apoptotic Volume Decrease. Front Cell Dev Biol; doi: 10.3389/fcell.2020.611211 [Online 25 November 2020].
]
Perez Kerkvliet C, Dwyer AR, Diep CH, Oakley RH, Liddle C, Cidlowski JA, Lange CA. 2020. Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer.
Breast Cancer Res
; doi: 10.1186/s13058-020-01277-8 [Online 1 May 2020]. [
Abstract
Perez Kerkvliet C, Dwyer AR, Diep CH, Oakley RH, Liddle C, Cidlowski JA, Lange CA. 2020. Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer. Breast Cancer Res; doi: 10.1186/s13058-020-01277-8 [Online 1 May 2020].
]
Cain DW, Cidlowski JA. 2020. After 62 years of regulating immunity, dexamethasone meets COVID-19.
Nat Rev Immunol
20(10):587-588. [
Abstract
Cain DW, Cidlowski JA. 2020. After 62 years of regulating immunity, dexamethasone meets COVID-19. Nat Rev Immunol 20(10):587-588.
]
Patt M, Gysi J, Faresse N, Cidlowski JA, Odermatt A. 2020. Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211.
Mol Cell Endocrinol
; doi: 10.1016/j.mce.2020.110873 [Online 22 June 2020]. [
Abstract
Patt M, Gysi J, Faresse N, Cidlowski JA, Odermatt A. 2020. Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211. Mol Cell Endocrinol; doi: 10.1016/j.mce.2020.110873 [Online 22 June 2020].
]
Cruz-Topete D, Oakley RH, Cidlowski JA. 2020. Glucocorticoid Signaling and the Aging Heart. Front Endocrinol (Lausanne); doi: 10.3389/fendo.2020.00347 [Online 27 May 2020]. [
Abstract
Cruz-Topete D, Oakley RH, Cidlowski JA. 2020. Glucocorticoid Signaling and the Aging Heart. Front Endocrinol (Lausanne); doi: 10.3389/fendo.2020.00347 [Online 27 May 2020].
]
Diaz-Jimenez David, Petrillo Maria Grazia, Busada Jonathan, Hermoso Marcela A., Cidlowski John A. 2020. Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4.
J Biol Chem
; doi: 10.1074/jbc.RA119.010894 [Online 27 January 2020]. [
Abstract
Diaz-Jimenez David, Petrillo Maria Grazia, Busada Jonathan, Hermoso Marcela A., Cidlowski John A. 2020. Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4. J Biol Chem; doi: 10.1074/jbc.RA119.010894 [Online 27 January 2020].
]
Quinn MA, McCalla A, He B, Xu X, Cidlowski JA. Silencing of Maternal Hepatic Glucocorticoid Receptor Is Essential for Normal Fetal Development in Mice.
Communications Biology
2019 2:104. [
Abstract
Quinn MA, McCalla A, He B, Xu X, Cidlowski JA. Silencing of Maternal Hepatic Glucocorticoid Receptor Is Essential for Normal Fetal Development in Mice. Communications Biology 2019 2:104.
]
Cruz-Topete D, Oakley RH, Burford NG, Myers PH, Xu X, Cidlowski JA. Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure.
Journal of the American Heart Association
2019 8(15):e011012-. [
Abstract
Cruz-Topete D, Oakley RH, Burford NG, Myers PH, Xu X, Cidlowski JA. Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure. Journal of the American Heart Association 2019 8(15):e011012-.
]
Petrillo MG, Oakley RH, Cidlowski JA. Beta-Arrestin-1 inhibits glucocorticoid receptor turnover and alters glucocorticoid signaling.
The Journal of Biological Chemistry
2019 294(29):11225-11239. [
Abstract
Petrillo MG, Oakley RH, Cidlowski JA. Beta-Arrestin-1 inhibits glucocorticoid receptor turnover and alters glucocorticoid signaling. The Journal of Biological Chemistry 2019 294(29):11225-11239.
]
Busada JT, Ramamoorthy S, Cain DW, Xu X, Cook DN, Cidlowski JA. Endogenous Glucocorticoids Prevent Gastric Metaplasia by Suppressing Spontaneous Inflammation.
The Journal of Clinical Investigation
2019 129(3):1345-1358. [
Abstract
Busada JT, Ramamoorthy S, Cain DW, Xu X, Cook DN, Cidlowski JA. Endogenous Glucocorticoids Prevent Gastric Metaplasia by Suppressing Spontaneous Inflammation. The Journal of Clinical Investigation 2019 129(3):1345-1358.
]
Oakley RH, Busillo JM, Cidlowski JA. Cross-talk between the Glucocorticoid Receptor and MyoD Family Inhibitor Domain Containing Protein Provides a New Mechanism for Generating Tissue-Specific Responses to Glucocorticoids.
The Journal of biological chemistry
2017 292(14):5825-5844. [
Abstract
Oakley RH, Busillo JM, Cidlowski JA. Cross-talk between the Glucocorticoid Receptor and MyoD Family Inhibitor Domain Containing Protein Provides a New Mechanism for Generating Tissue-Specific Responses to Glucocorticoids. The Journal of biological chemistry 2017 292(14):5825-5844.
]
Whirledge S, Cidlowski JA. Glucocorticoids and Reproduction: Traffic Control on the Road to Reproduction.
Trends in Endocrinology and Metabolism
2017 28(6):399-415. [
Abstract
Whirledge S, Cidlowski JA. Glucocorticoids and Reproduction: Traffic Control on the Road to Reproduction. Trends in Endocrinology and Metabolism 2017 28(6):399-415.
]
Kadmiel M, Janoshazi A, Cidlowski JA. Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye.
Experimental Eye Research
2016
152()
:10-33. [
Abstract
Kadmiel M, Janoshazi A, Cidlowski JA. Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye. Experimental Eye Research 2016 152():10-33.
]
Cruz-Topete D, He B, Chang J, Xu X, Cidlowski JA. Krüppel-like Factor 13 Is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death.
The Journal of biological chemistry
2016 291(37):19374-19386. [
Abstract
Cruz-Topete D, He B, Chang J, Xu X, Cidlowski JA. Krüppel-like Factor 13 Is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death. The Journal of biological chemistry 2016 291(37):19374-19386.
]
Cruz-Topete, D, Myers, P, Foley, J , Willis, M, Cidlowski, J. Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice.
Endocrinology
2016 157(7):2759-2771. [
Abstract
Cruz-Topete, D, Myers, P, Foley, J , Willis, M, Cidlowski, J. Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice. Endocrinology 2016 157(7):2759-2771.
]
Quinn MA, Cidlowski JA. Endogenous hepatic glucocorticoid receptor signaling coordinates sex-biased inflammatory gene expression.
FASEB journal: official publication of the Federation of American Societies for Experimental Biology
2016 30(2):971-982. [
Abstract
Quinn MA, Cidlowski JA. Endogenous hepatic glucocorticoid receptor signaling coordinates sex-biased inflammatory gene expression. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 2016 30(2):971-982.
]
Bortner CD, Scoltock AB, Cain DW, Cidlowski JA. T-cell development of resistance to apoptosis is driven by a metabolic shift in carbon source and altered activation of death pathways.
Cell death and differentiation
2016
23(5)
:889-902. [
Abstract
Bortner CD, Scoltock AB, Cain DW, Cidlowski JA. T-cell development of resistance to apoptosis is driven by a metabolic shift in carbon source and altered activation of death pathways. Cell death and differentiation 2016 23(5):889-902.
]
He B, Cruz-Topete D, Oakley RH, Xiao X, Cidlowski JA. Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver.
Molecular and cellular biology
2015
36(5)
:714-730. [
Abstract
He B, Cruz-Topete D, Oakley RH, Xiao X, Cidlowski JA. Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver. Molecular and cellular biology 2015 36(5):714-730.
]
Whirledge SD, Oakley RH, Myers PH, Lydon JP, DeMayo F, Cidlowski JA. Uterine glucocorticoid receptors are critical for fertility in mice through control of embryo implantation and decidualization.
Proceedings of the National Academy of Sciences of the United States of America
2015 112(49):15166-15171. [
Abstract
Whirledge SD, Oakley RH, Myers PH, Lydon JP, DeMayo F, Cidlowski JA. Uterine glucocorticoid receptors are critical for fertility in mice through control of embryo implantation and decidualization. Proceedings of the National Academy of Sciences of the United States of America 2015 112(49):15166-15171.
]
Cruz-Topete D, Cidlowski JA. One hormone, two actions: anti- and pro-inflammatory effects of glucocorticoids.
Neuroimmunomodulation
2015
22(1-2)
:20-32. [
Abstract
Cruz-Topete D, Cidlowski JA. One hormone, two actions: anti- and pro-inflammatory effects of glucocorticoids. Neuroimmunomodulation 2015 22(1-2):20-32.
]
Bortner CD, Cidlowski JA. Ion channels and apoptosis in cancer.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
2014
369(1638)
:20130104-. [
Abstract
Bortner CD, Cidlowski JA. Ion channels and apoptosis in cancer. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2014 369(1638):20130104-.
]
Gruver-Yates AL, Quinn MA, Cidlowski JA. Analysis of glucocorticoid receptors and their apoptotic response to dexamethasone in male murine B cells during development.
Endocrinology
155(2)
:463-474, 2014. [
Abstract
Gruver-Yates AL, Quinn MA, Cidlowski JA. Analysis of glucocorticoid receptors and their apoptotic response to dexamethasone in male murine B cells during development. Endocrinology 155(2):463-474, 2014.
]
Franco R, Bortner CD, Schmitz I, Cidlowski JA. Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.
Apoptosis: an international journal on programmed cell death
19(1)
:117-134, 2014. [
Abstract
Franco R, Bortner CD, Schmitz I, Cidlowski JA. Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1. Apoptosis: an international journal on programmed cell death 19(1):117-134, 2014.
]
Kadmiel M, Cidlowski JA. Glucocorticoid Receptor Signaling in Health and Disease.
Trends in Pharmacological Sciences
2013 34(9):518-530. [
Abstract
Kadmiel M, Cidlowski JA. Glucocorticoid Receptor Signaling in Health and Disease. Trends in Pharmacological Sciences 2013 34(9):518-530.
]
Gruver-Yates AL, Cidlowski JA. Tissue-specific actions of glucocorticoids on apoptosis: a double-edged sword. Cells 2013 2(2):202-223. [
Abstract
Gruver-Yates AL, Cidlowski JA. Tissue-specific actions of glucocorticoids on apoptosis: a double-edged sword. Cells 2013 2(2):202-223.
]
Oakley RH, Cidlowski JA. The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease.
Journal of Allergy and Clinical Immunology
2013
132(5)
:1033-1044. [
Abstract
Oakley RH, Cidlowski JA. The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease. Journal of Allergy and Clinical Immunology 2013 132(5):1033-1044.
]
Whirledge S, Cidlowski JA. A role for glucocorticoids in stress-impaired reproduction: beyond the hypothalamus and pituitary.
Endocrinology
154(12)
:4450-4468, 2013. [
Abstract
Whirledge S, Cidlowski JA. A role for glucocorticoids in stress-impaired reproduction: beyond the hypothalamus and pituitary. Endocrinology 154(12):4450-4468, 2013.
]
Revollo JR, Oakley RH, Lu NZ, Kadmiel M, Gandhavadi M, Cidlowski JA. HES1 Is a Master Regulator of Glucocorticoid Receptor–Dependent Gene Expression.
Science Signaling
6(304)
:ra103-, 2013. [
Abstract
Revollo JR, Oakley RH, Lu NZ, Kadmiel M, Gandhavadi M, Cidlowski JA. HES1 Is a Master Regulator of Glucocorticoid Receptor–Dependent Gene Expression. Science Signaling 6(304):ra103-, 2013.
]
Whirledge S, Xu X, Cidlowski JA. Global gene expression analysis in human uterine epithelial cells defines new targets of glucocorticoid and estradiol antagonism.
Biology of Reproduction
89(3)
:66, 2013. [
Abstract
Whirledge S, Xu X, Cidlowski JA. Global gene expression analysis in human uterine epithelial cells defines new targets of glucocorticoid and estradiol antagonism. Biology of Reproduction 89(3):66, 2013.
]
Oakley RH, Ren R, Cruz-Topete D, Bird GS, Myers PH, Boyle MC, Schneider MD, Willis MS, Cidlowski JA. Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease.
Proceedings of the National Academy of Sciences of the United States of America
110(42)
:17035-40, 2013. [
Abstract
Oakley RH, Ren R, Cruz-Topete D, Bird GS, Myers PH, Boyle MC, Schneider MD, Willis MS, Cidlowski JA. Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease. Proceedings of the National Academy of Sciences of the United States of America 110(42):17035-40, 2013.
]
Oakley RH, Revollo J, Cidlowski JA. Glucocorticoids regulate arrestin gene expression and redirect the signaling profile of G protein-coupled receptors.
Proceedings of the National Academy of Sciences of the United States of America
109(43)
:17591-6, 2012. [
Abstract
Oakley RH, Revollo J, Cidlowski JA. Glucocorticoids regulate arrestin gene expression and redirect the signaling profile of G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America 109(43):17591-6, 2012.
]
Ren R, Oakley RH, Cruz-Topete D, Cidlowski JA. Dual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosis.
Endocrinology
153(11)
:5346-60, 2012. [
Abstract
Ren R, Oakley RH, Cruz-Topete D, Cidlowski JA. Dual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosis. Endocrinology 153(11):5346-60, 2012.
]
Jewell CM, Scoltock AB, Hamel BL, Yudt MR, Cidlowski JA. Complex human glucocorticoid receptor dim mutations define glucocorticoid induced apoptotic resistance in bone cells.
Endocrinology
26(2)
:244-56, 2012. [
Abstract
Jewell CM, Scoltock AB, Hamel BL, Yudt MR, Cidlowski JA. Complex human glucocorticoid receptor dim mutations define glucocorticoid induced apoptotic resistance in bone cells. Endocrinology 26(2):244-56, 2012.
]
Bortner CD, Scoltock AB, Sifre MI, Cidlowski JA. Osmotic stress resistance imparts acquired anti-apoptotic mechanisms in lymphocytes..
The Journal of biological chemistry
287(9)
:6284-95, 2012. [
Abstract
Bortner CD, Scoltock AB, Sifre MI, Cidlowski JA. Osmotic stress resistance imparts acquired anti-apoptotic mechanisms in lymphocytes.. The Journal of biological chemistry 287(9):6284-95, 2012.
]
Gross KL, Oakley RH, Scoltock AB, Jewel CM, Cidlowski JA. Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance.
Molecular Endocrinology
25(7)
:1087-1099, 2011. [
Abstract
Gross KL, Oakley RH, Scoltock AB, Jewel CM, Cidlowski JA. Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance. Molecular Endocrinology 25(7):1087-1099, 2011.
]
Busillo JM, Azzam KM, Cidlowski JA. Glucocorticoids sensitize the innate immune system through regulation of the NLRP3 inflammasome.
The Journal of biological chemistry
286(44)
:38703-13, 2011. [
Abstract
Busillo JM, Azzam KM, Cidlowski JA. Glucocorticoids sensitize the innate immune system through regulation of the NLRP3 inflammasome. The Journal of biological chemistry 286(44):38703-13, 2011.
]
Smith LK, Shah RR, Cidlowski JA. Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis.
The Journal of biological chemistry
285(47)
:36698-36708, 2010. [
Abstract
Smith LK, Shah RR, Cidlowski JA. Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis. The Journal of biological chemistry 285(47):36698-36708, 2010.
]
Ajiro K, Scoltock A , Smith LK, Ashasima M, Cidlowski JA. Reciprocal Epigenetic Modification of Histone H2B occurs in Chromatin during Apoptosis in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America
17(6)
:984-993, 2010. [
Abstract
Ajiro K, Scoltock A , Smith LK, Ashasima M, Cidlowski JA. Reciprocal Epigenetic Modification of Histone H2B occurs in Chromatin during Apoptosis in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America 17(6):984-993, 2010.
]
Gross KL, Lu NZ, Cidlowski JA. Molecular mechanisms regulating glucocorticoid sensitivity and resistance. Molecular and cellular endocrinology 2009 300(1-2):7-16. [
Abstract
Gross KL, Lu NZ, Cidlowski JA. Molecular mechanisms regulating glucocorticoid sensitivity and resistance. Molecular and cellular endocrinology 2009 300(1-2):7-16.
]
Ajiro K, Bortner CD, Westmoreland J, Cidlowski JA. 2008. An endogenous calcium-dependent, caspase-independent intranuclear degradation pathway in thymocyte nuclei: antagonism by physiological concentrations of K(+) ions.
Exp Cell Res
314(6)
:1237-1249. [
Abstract
Ajiro K, Bortner CD, Westmoreland J, Cidlowski JA. 2008. An endogenous calcium-dependent, caspase-independent intranuclear degradation pathway in thymocyte nuclei: antagonism by physiological concentrations of K(+) ions. Exp Cell Res 314(6):1237-1249.
]
Franco R, Dehaven WI, Sifre MI, Bortner CD, Cidlowski JA. Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis.
J Biol Chem
283(52)
:36071-36087, 2008. [
Abstract
Franco R, Dehaven WI, Sifre MI, Bortner CD, Cidlowski JA. Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis. J Biol Chem 283(52):36071-36087, 2008.
]
Galliher-Beckley AJ, Williams JG, Collins JB, Cidlowski JA. Glycogen synthase kinase 3beta-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles.
Molecular and cellular biology
28(24)
:7309-7322, 2008. [
Abstract
Galliher-Beckley AJ, Williams JG, Collins JB, Cidlowski JA. Glycogen synthase kinase 3beta-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles. Molecular and cellular biology 28(24):7309-7322, 2008.
]
Gross KL, Cidlowski JA. Tissue-specific glucocorticoid action: A family affair.
Trends in endocrinology and metabolism: TEM
19(9)
:331-339, 2008. [
Abstract
Gross KL, Cidlowski JA. Tissue-specific glucocorticoid action: A family affair. Trends in endocrinology and metabolism: TEM 19(9):331-339, 2008.
]
Bortner CD, Sifre MI, Cidlowski JA. Cationic gradient reversal and cytoskeleton-independent volume fegulatory pathways define an early stage of apoptosis.
The Journal of Biological Chemistry
283(11)
:7219-7229, 2008. [
Abstract
Bortner CD, Sifre MI, Cidlowski JA. Cationic gradient reversal and cytoskeleton-independent volume fegulatory pathways define an early stage of apoptosis. The Journal of Biological Chemistry 283(11):7219-7229, 2008.
]
Lu NZ, Collins JB, Grissom SF, Cidlowski JA. Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor.
Molecular and Cellular Biology
27(20)
:7143-7160, 2007. [
Abstract
Lu NZ, Collins JB, Grissom SF, Cidlowski JA. Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor. Molecular and Cellular Biology 27(20):7143-7160, 2007.
]
Franco R, Panayiotidis MI, Cidlowski JA. Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation.
Journal of Biological Chemistry
282(42)
:30452-30465, 2007. [
Abstract
Franco R, Panayiotidis MI, Cidlowski JA. Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation. Journal of Biological Chemistry 282(42):30452-30465, 2007.
]
Lewis-Tuffin LJ, Jewell CM, Bienstock RJ, Collins JB and Cidlowski JA. Human glucocorticoid receptor ? binds RU-486 and is transcriptionally active.
Molecular and Cellular Biology
p. 2266-2282
, Mar 2007. [
Abstract
Lewis-Tuffin LJ, Jewell CM, Bienstock RJ, Collins JB and Cidlowski JA. Human glucocorticoid receptor ? binds RU-486 and is transcriptionally active. Molecular and Cellular Biology p. 2266-2282, Mar 2007.
]
Lu NZ and Cidlowski JA. Glucocorticoid receptor isoforms generate transcription specificity.
Trends in Cell Biology
16(6):
301-307, 2006. [
Abstract
Lu NZ and Cidlowski JA. Glucocorticoid receptor isoforms generate transcription specificity. Trends in Cell Biology 16(6):301-307, 2006.
]
Franco R, Bortner CD and Cidlowski JA. Potential roles of electrogenic ion transport and plasma membrane depolarization in apoptosis.
J. of Membrane Biology
209
: 43-58, 2006. [
Abstract
Franco R, Bortner CD and Cidlowski JA. Potential roles of electrogenic ion transport and plasma membrane depolarization in apoptosis. J. of Membrane Biology 209: 43-58, 2006.
]
Franco R and Cidlowski JA. SLCO/OATP-like transport of glutathione in FasL-induced apoptosis.
Journal of Biological Chemistry
281
(40):29542-29557, 2006. [
Abstract
Franco R and Cidlowski JA. SLCO/OATP-like transport of glutathione in FasL-induced apoptosis. Journal of Biological Chemistry 281 (40):29542-29557, 2006.
]
Smoak K and Cidlowski JA. Glucocorticoids regulate tristetetraprolin synthesis and posttrancriptionally regulate tumor necrosis factor alpha inflammatory signaling.
Molecular and Celullar Biology
26(23):
9126-9135, 2006. [
Abstract
Smoak K and Cidlowski JA. Glucocorticoids regulate tristetetraprolin synthesis and posttrancriptionally regulate tumor necrosis factor alpha inflammatory signaling. Molecular and Celullar Biology 26(23):9126-9135, 2006.
]
G. Heimlich and Cidlowski JA. Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells.
J. Biol. Chem.
281:
2232-2241, 2006. [
Abstract
G. Heimlich and Cidlowski JA. Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells. J. Biol. Chem. 281: 2232-2241, 2006.
]
Schaaf MJM, Lewis-Tuffin LJ and Cidlowski JA. Ligand-Selective Targeting of the Glucocorticoid Receptor to Nuclear Subdomains is associated with Decreased Receptor Mobility.
Molecular Endocrinology
19(6)
: 1501-1515, 2005. [
Abstract
Schaaf MJM, Lewis-Tuffin LJ and Cidlowski JA. Ligand-Selective Targeting of the Glucocorticoid Receptor to Nuclear Subdomains is associated with Decreased Receptor Mobility. Molecular Endocrinology 19(6): 1501-1515, 2005.
]
Lu NZ and Cidlowski JA. Translational Regulatory Mechanisms Generate N-terminal Glucocorticoid Receptor Isoforms with Unique Transcriptional Target Genes.
Molecular Cell.
Vol.18,
331-342 April 29, 2005. [
Abstract
Lu NZ and Cidlowski JA. Translational Regulatory Mechanisms Generate N-terminal Glucocorticoid Receptor Isoforms with Unique Transcriptional Target Genes. Molecular Cell. Vol.18, 331-342 April 29, 2005.
]
Hermoso MA, Matsuguchi T, Smoak K and Cidlowski JA. Glucocorticoids and Tumor Necrosis Factor Alpha Cooperatively Regulate Toll-Like Receptor 2 Gene Expression.
Molecular and Cellular Biology,
p.
4743-4756
,
June 2004.
[
Abstract
Hermoso MA, Matsuguchi T, Smoak K and Cidlowski JA. Glucocorticoids and Tumor Necrosis Factor Alpha Cooperatively Regulate Toll-Like Receptor 2 Gene Expression. Molecular and Cellular Biology, p.4743-4756, June 2004.
]
Back
to Top
Last Reviewed: April 14, 2026