Toxicoinformatics Group | National Institute of Environmental Health Sciences Skip Navigation Toxicoinformatics Group Close the left navigation Add Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS. Visit the NTP Website Predictive Toxicology Branch Scott S. Auerbach, Ph.D. Leader, Toxicoinformatics Tel 984-287-3108 [email protected] Research Summary The Toxicoinformatics Group leads the development of data analytic approaches related to Tox21 data and provides informatics support for a variety of projects within the Biomolecular Screening Branch  and across the National Toxicology Program. Specific projects include: Development of toxicogenomic models that predict apical toxicological outcomes Evaluation of methods for scaling toxicogenomic technologies In vitro / In vivo extrapolation Analytics pipeline development for Tox21 high throughput screening data Development of network-based inference  approaches for biological read-across using Tox21 data Development of software for genomic benchmark dose analysis Scientists & Staff Scott S. Auerbach, Ph.D. Leader, Toxicoinformatics Tel 984-287-3108 [email protected] Frank G. Chao, Ph.D. Computational Biologist Tel 984-287-4066 [email protected] Jui-Hua Hsieh, Ph.D. Staff Scientist Tel 984-287-3142 [email protected] Frederick M. Parham, Ph.D. Mathematical Statistician Tel 984-287-3169 [email protected] Zicong Wang Contractor - Software Developer Tel 984-287-4494 [email protected] Recent Publications Ngan D, Ye L, Hsieh J, Xu T, Zhao J, Sakamuru S, Tao D, LeClair C, Zhao T, Rossoshek A, Reif D, Simeonov A, Xia M, Huang R. Impact of Chemical Quality on High-Throughput in Vitro Assays: A Tox21 Study. Chemical research in toxicology 2026 Apr 20;39(4):624-635. Abstract Ngan D, Ye L, Hsieh J, Xu T, Zhao J, Sakamuru S, Tao D, LeClair C, Zhao T, Rossoshek A, Reif D, Simeonov A, Xia M, Huang R. Impact of Chemical Quality on High-Throughput in Vitro Assays: A Tox21 Study. Chemical research in toxicology. 2026 Apr 20 Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13 NIEHS Report Series 2026 Apr [Epub ahead of print]. Abstract Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,4-Dichlorobenzene (CASRN 106-46-7) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 13 NIEHS Report Series. 2026 Apr Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12 NIEHS Report Series 2026 Apr [Epub ahead of print]. Abstract Auerbach S, Cora M, Liu Y, Luh J, Prince L, Roberts G, Shipkowski K, Waidyanatha S. NIEHS Report on the In Vivo Repeat Dose Biological Potency Studies of 1,2-Dichlorobenzene (CASRN 95-50-1) in Female Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6D2F1/Crl Mice (Whole-body Inhalation Studies): NIEHS Report 12 NIEHS Report Series. 2026 Apr Bommarito P, Taylor K, Rooney A, Addo K, Auerbach S, Blain R, Ferguson K, Gaston S, Hall S, Jackson C, Lemeris C, Silva R, Tracy W, Walker V, Howdeshell K. Systematic evidence map on the association between exposure to personal care products and fetal growth. Environment international 2026 Mar;209:110147. Abstract Bommarito P, Taylor K, Rooney A, Addo K, Auerbach S, Blain R, Ferguson K, Gaston S, Hall S, Jackson C, Lemeris C, Silva R, Tracy W, Walker V, Howdeshell K. Systematic evidence map on the association between exposure to personal care products and fetal growth. Environment international. 2026 Mar Cong G, Patton R, Chao F, Svoboda D, Erickson J, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Auerbach S. Transplatformer: translating toxicogenomic profiles between generations of platforms. BMC bioinformatics 2026 Jan 30;27(1):. Abstract Cong G, Patton R, Chao F, Svoboda D, Erickson J, Balik-Meisner M, Mav D, Phadke D, Scholl E, Shah R, Auerbach S. Transplatformer: translating toxicogenomic profiles between generations of platforms. BMC bioinformatics. 2026 Jan 30 More Recent Publications from PubMed Software Tox21 Toolbox The Tox21 toolbox contains useful tools for accessing and visualizing the Tox21 quantitative high throughput screening (qHTS) 10K library data, as well as integrating with other publicly available data. Related Links Toxicology Back to Top Last Reviewed: January 02, 2026