Adult and Juvenile Myositis (Studies in the Natural History & Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflamm
Source: https://www.niehs.nih.gov/research/atniehs/labs/crb/studies/myopathies
Archived: 2026-04-23 17:15
Adult and Juvenile Myositis (Studies in the Natural History & Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies) | National Institute of Environmental Health Sciences
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Adult and Juvenile Myositis (Studies in the Natural History & Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies)
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Study Background
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This study will evaluate subjects with adult- and childhood-onset myositis to learn more about their causes and the immune system changes and medical problems associated with them. Myositis is an inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability.
This study also intends to investigate the genetic and environmental risk factors involved in the development of myositis, an autoimmune muscle disease that causes chronic muscle weakness. Adults and children diagnosed with myositis may enroll by completing questionnaires and donating blood and urine samples.
Eligibility Criteria
Individuals meeting probable or definite criteria for Idiopathic Inflammatory Myopathies (IIM).
Patient or parent/guardian must give informed consent to all or part of the study.
Selected patients with undefined illnesses who may have weakness, myalgias, or an elevated CK may be evaluated to establish a diagnosis and, if they are found to have IIM, would be offered the opportunity to enter the study.
For patients with at least one first-degree relative affected with IIIM, we will enroll all available first degree relatives (affected and unaffected) to participate in the genetics portion of the protocol.
Severe medical disease requiring intensive care or any other conditions in which the drawing of blood or undergoing procedures needed for the study is not deemed medically appropriate will be excluded from the study.
Principal Investigator
Lisa G. Rider, M.D.
Head and Senior Clinician
Tel 301-451-6272
[email protected]
Lead Associate Investigator
Adam I. Schiffenbauer, M.D.
Deputy Head and Associate Research Physician
Tel 301-451-6270
[email protected]
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Last Reviewed: December 30, 2025
Skip Navigation
Adult and Juvenile Myositis (Studies in the Natural History & Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies)
Close the left navigation
Add
Study Background
Looking to join this study?
Visit the
Join an
NIEHS Study
Website
For More Information
ClinicalTrials.gov
NIH Clinical Studies
This study will evaluate subjects with adult- and childhood-onset myositis to learn more about their causes and the immune system changes and medical problems associated with them. Myositis is an inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability.
This study also intends to investigate the genetic and environmental risk factors involved in the development of myositis, an autoimmune muscle disease that causes chronic muscle weakness. Adults and children diagnosed with myositis may enroll by completing questionnaires and donating blood and urine samples.
Eligibility Criteria
Individuals meeting probable or definite criteria for Idiopathic Inflammatory Myopathies (IIM).
Patient or parent/guardian must give informed consent to all or part of the study.
Selected patients with undefined illnesses who may have weakness, myalgias, or an elevated CK may be evaluated to establish a diagnosis and, if they are found to have IIM, would be offered the opportunity to enter the study.
For patients with at least one first-degree relative affected with IIIM, we will enroll all available first degree relatives (affected and unaffected) to participate in the genetics portion of the protocol.
Severe medical disease requiring intensive care or any other conditions in which the drawing of blood or undergoing procedures needed for the study is not deemed medically appropriate will be excluded from the study.
Principal Investigator
Lisa G. Rider, M.D.
Head and Senior Clinician
Tel 301-451-6272
[email protected]
Lead Associate Investigator
Adam I. Schiffenbauer, M.D.
Deputy Head and Associate Research Physician
Tel 301-451-6270
[email protected]
Back
to Top
Last Reviewed: December 30, 2025