This is the released version of rqt; for the devel version, see rqt.

rqt: utilities for gene-level meta-analysis


Bioconductor version: Release (3.22)

Despite the recent advances of modern GWAS methods, it still remains an important problem of addressing calculation an effect size and corresponding p-value for the whole gene rather than for single variant. The R- package rqt offers gene-level GWAS meta-analysis. For more information, see: "Gene-set association tests for next-generation sequencing data" by Lee et al (2016), Bioinformatics, 32(17), i611-i619, .

Author: Ilya Zhbannikov [aut, cre], Konstantin Arbeev [aut], Anatoliy Yashin [aut]

Maintainer: Ilya Zhbannikov <ilya.zhbannikov at duke.edu>

Citation (from within R, enter citation("rqt")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("rqt")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("rqt")

Details

biocViews GenomeWideAssociation, PrincipalComponent, Regression, Sequencing, Software, StatisticalMethod, Survival
Version 1.36.0
In Bioconductor since BioC 3.5 (R-3.4) (9 years)
License GPL
Depends R (>= 3.4), SummarizedExperiment
Imports stats, Matrix, ropls, methods, car, RUnit, metap, CompQuadForm, glmnet, utils, pls
System Requirements
URL https://github.com/izhbannikov/rqt
Bug Reports https://github.com/izhbannikov/rqt/issues
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Package Archives

Follow Installation instructions to use this package in your R session.