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Agonistic GITR treatment enhances antitumor immune responses and suppresses tumor progression in pancreatic ductal adenocarcinoma. J Gastroenterol. 2026 Feb 01. Robatel S, Hillen H, Mutisheva I, Müller JC, Wartenberg M, Ma F, Bäriswyl L, Evenepoel J, Scheele CLGJ, Lee DJ, Modlin RL, Kessler U, Nobis M, Z'graggen K, Schenk M. PMID: 41620983.
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Elevated co-expression of TIMM17A and NMT1 is associated with poor survival in non-small cell lung cancer. Sci Rep. 2025 Oct 13; 15(1):35597. Chan AA, Sankar K, Reckamp KL, Díaz B, Lee DJ. PMID: 41083501; PMCID: PMC12518850.
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Primary Cutaneous Melanoma Microbiome Is Associated with Overall Survival and Recurrence. J Invest Dermatol. 2026 Mar; 146(3):771-781.e4. Chan AA, Noguti J, Maverakis Ramirez N, Navarrete M, Lee DJ. PMID: 40835086.
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TREM-1 as a novel immunotherapeutic target to treat pancreatic ductal adenocarcinoma. Mol Ther Oncol. 2025 Sep 18; 33(3):201034. Gross L, Mutisheva I, Hillen H, Robatel S, Wartenberg M, Ma F, Bäriswyl L, Lee DJ, Modlin RL, Z'graggen K, Schenk M. PMID: 40917508; PMCID: PMC12410479.
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Mammary tissue microbiome analysis in PyMT mice reveals Methylobacteria as a commensal organism with potential therapeutic applications. Transl Oncol. 2025 Sep; 59:102451. Chan AA, Caron C, Navarrete M, Lee CK, Noguti J, Bui JD, Lee DJ. PMID: 40570700; PMCID: PMC12302725.
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N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma. Cancer Res Commun. 2024 07 01; 4(7):1815-1833. Geroyska S, Mejia I, Chan AA, Navarrete M, Pandey V, Kharpatin S, Noguti J, Wang F, Srole D, Chou TF, Wohlschlegel J, Nemeth E, Damoiseaux R, Shackelford DB, Lee DJ, Díaz B. PMID: 38949950; PMCID: PMC11270646.
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Quantitative Aggregation of Microbiome Sequencing Data Provides Insights into the Associations between the Skin Microbiome and Psoriasis. JID Innov. 2024 Jan; 4(1):100249. Chan AA, Tran PT, Lee DJ. PMID: 38282647; PMCID: PMC10810833.
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Alcohol and Smoking Cessation as Potential Modulators for Smoking-Associated Psoriasis Risk in Postmenopausal Women: The Women's Health Initiative. Am J Clin Dermatol. 2023 Mar; 24(2):325-332. Li W, Chan AA, Han J, Chlebowski RT, Lee DJ. PMID: 36662365; PMCID: PMC9968247.
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Acne Keloidalis Nuchae is Associated with Cutis Verticis Gyrata. Clin Cosmet Investig Dermatol. 2022; 15:1421-1427. Umar S, Lullo JJ, Carter MJ, Shitabata PK, Lee DJ. PMID: 35924256; PMCID: PMC9342927.
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BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma. J Immunother Cancer. 2022 06; 10(6). Kremenovic M, Chan AA, Feng B, Bäriswyl L, Robatel S, Gruber T, Tang L, Lee DJ, Schenk M. PMID: 35732347; PMCID: PMC9226922.
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The Effect of Systemic Antibiotics for Suppurative Skin and Soft Tissue Infections on the Skin Microbiome. Open Forum Infect Dis. 2022 May; 9(5):ofac141. Chan AA, Flores EA, Navarrete M, Phan Tran D, Lee DJ, Miller LG. PMID: 35450081; PMCID: PMC9017368.
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Tocilizumab overcomes chemotherapy resistance in mesenchymal stem-like breast cancer by negating autocrine IL-1A induction of IL-6. NPJ Breast Cancer. 2022 Mar 08; 8(1):30. Chung AW, Kozielski AJ, Qian W, Zhou J, Anselme AC, Chan AA, Pan PY, Lee DJ, Chang JC. PMID: 35260569; PMCID: PMC8904846.
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Prognostic biomarkers of cutaneous melanoma. Photodermatol Photoimmunol Photomed. 2022 Sep; 38(5):418-434. Ding L, Gosh A, Lee DJ, Emri G, Huss WJ, Bogner PN, Paragh G. PMID: 34981569.
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A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer. Sci Transl Med. 2021 12 15; 13(624):eabj5070. Chung AW, Anand K, Anselme AC, Chan AA, Gupta N, Venta LA, Schwartz MR, Qian W, Xu Y, Zhang L, Kuhn J, Patel T, Rodriguez AA, Belcheva A, Darcourt J, Ensor J, Bernicker E, Pan PY, Chen SH, Lee DJ, Niravath PA, Chang JC. PMID: 34910551.
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Association between baseline insulin resistance and psoriasis incidence: the Women's Health Initiative. Arch Dermatol Res. 2022 Nov; 314(9):869-880. Chan AA, Li H, Li W, Pan K, Yee JK, Chlebowski RT, Lee DJ. PMID: 34816303; PMCID: PMC9512862.
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A Retrospective Cohort Study and Clinical Classification System of Acne Keloidalis Nuchae. J Clin Aesthet Dermatol. 2021 Apr; 14(4):E61-E67. Umar S, Lee DJ, Lullo JJ. PMID: 34055191; PMCID: PMC8142833.
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Analysis of psoriasis-related posts on Twitter: An abundance of patient-driven advocacy versus a scarcity of dermatologists. J Am Acad Dermatol. 2021 12; 85(6):1579-1581. Li W, Le N, Lee DJ, Reuter K. PMID: 33171165.
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N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells. Sci Rep. 2020 07 20; 10(1):11952. Chen YC, Navarrete MS, Wang Y, McClintock NC, Sakurai R, Wang F, Chen KT, Chou TF, Rehan VK, Lee DJ, Diaz B. PMID: 32686708; PMCID: PMC7371688.
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Hidradenitis suppurativa through the lens of YouTube: A cross-sectional analysis. J Am Acad Dermatol. 2021 05; 84(5):1398-1399. Li W, Ma JE, Chan AA, Lee DJ, Smogorzewski J. PMID: 32522514.
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Characterization of a Myeloid Activation Signature that Correlates with Survival in Melanoma Patients. Cancers (Basel). 2020 May 31; 12(6). Kremenovic M, Rombini N, Chan AA, Gruber T, Bäriswyl L, Lee DJ, Schenk M. PMID: 32486450; PMCID: PMC7352688.
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Treatment of transient acantholytic dermatosis with liquid nitrogen. JAAD Case Rep. 2020 Apr; 6(4):341-343. Galamgam J, Lee DJ. PMID: 32258316; PMCID: PMC7103660.
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Insulin Resistance and Cancer-Specific and All-Cause Mortality in Postmenopausal Women: The Women's Health Initiative. J Natl Cancer Inst. 2020 02 01; 112(2):170-178. Pan K, Nelson RA, Wactawski-Wende J, Lee DJ, Manson JE, Aragaki AK, Mortimer JE, Phillips LS, Rohan T, Ho GYF, Saquib N, Shadyab AH, Nassir R, Rhee JJ, Hurria A, Chlebowski RT. PMID: 31184362; PMCID: PMC7019097.
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Cytotoxic T cell depletion with increasing epithelial abnormality in women with benign breast disease. Breast Cancer Res Treat. 2020 Feb; 180(1):55-61. Adhikary S, Hoskin TL, Stallings-Mann ML, Arshad M, Frost MH, Winham SJ, Peña A, Lee DJ, Murphy LM, Rakoff M, Denison LA, Knutson KL, Radisky DC, Visscher DW, Degnim AC. PMID: 31933142; PMCID: PMC7031204.
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Practical methods for effective vancomycin-resistant enterococci (VRE) surveillance: experience in a liver transplant surgical intensive care unit. Infect Control Hosp Epidemiol. 2018 10; 39(10):1178-1182. Linfield RY, Campeau S, Injean P, Gregson A, Kaldas F, Rubin Z, Kim T, Kunz D, Chan A, Lee DJ, Humphries RM, McKinnell JA. PMID: 30178725.
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Nivolumab-induced systemic vasculitis. JAAD Case Rep. 2018 Jul; 4(6):606-608. Kang A, Yuen M, Lee DJ. PMID: 30003129; PMCID: PMC6039753.
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Both the intratumoral immune and microbial microenvironment are linked to recurrence in human colon cancer: results from a prospective, multicenter nodal ultrastaging trial. Oncotarget. 2018 May 04; 9(34):23564-23576. Noguti J, Chan AA, Bandera B, Brislawn CJ, Protic M, Sim MS, Jansson JK, Bilchik AJ, Lee DJ. PMID: 29805756; PMCID: PMC5955112.
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The Negative Impact of Body Mass Index on the Tumor Microenvironment in Colon Cancer: Results of a Prospective Trial. Ann Surg Oncol. 2018 May; 25(5):1374-1380. Flaherty DC, Jalas JR, Sim MS, Stojadinovic A, Protic M, Lee DJ, Bilchik AJ. PMID: 29532344.
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Mycobacterium bovis Bacillus Calmette-Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function. Front Immunol. 2017; 8:965. Lardone RD, Chan AA, Lee AF, Foshag LJ, Faries MB, Sieling PA, Lee DJ. PMID: 28848560; PMCID: PMC5554507.
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Insights into Local Tumor Microenvironment Immune Factors Associated with Regression of Cutaneous Melanoma Metastases by Mycobacterium bovis Bacille Calmette-Guérin. Front Oncol. 2017; 7:61. Yang J, Jones MS, Ramos RI, Chan AA, Lee AF, Foshag LJ, Sieling PA, Faries MB, Lee DJ. PMID: 28424760; PMCID: PMC5380679.
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Characterization of the microbiome of nipple aspirate fluid of breast cancer survivors. Sci Rep. 2016 06 21; 6:28061. Chan AA, Bashir M, Rivas MN, Duvall K, Sieling PA, Pieber TR, Vaishampayan PA, Love SM, Lee DJ. PMID: 27324944; PMCID: PMC4914981.
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Cross-platform comparison of independent datasets identifies an immune signature associated with improved survival in metastatic melanoma. Oncotarget. 2016 Mar 22; 7(12):14415-28. Lardone RD, Plaisier SB, Navarrete MS, Shamonki JM, Jalas JR, Sieling PA, Lee DJ. PMID: 26883106; PMCID: PMC4924725.
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Prognostic Utility of Immunoprofiling in Colon Cancer: Results from a Prospective, Multicenter Nodal Ultrastaging Trial. J Am Coll Surg. 2016 07; 223(1):134-40. Flaherty DC, Lavotshkin S, Jalas JR, Torisu-Itakura H, Kirchoff DD, Sim MS, Lee DJ, Bilchik AJ. PMID: 27282965.
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Langerhans Cells Maintain Local Tissue Tolerance in a Model of Systemic Autoimmune Disease. J Immunol. 2015 Jul 15; 195(2):464-76. King JK, Philips RL, Eriksson AU, Kim PJ, Halder RC, Lee DJ, Singh RR. PMID: 26071559; PMCID: PMC4562401.
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Melanoma vaccines: mixed past, promising future. Surg Clin North Am. 2014 Oct; 94(5):1017-30, viii. Ozao-Choy J, Lee DJ, Faries MB. PMID: 25245965; PMCID: PMC4173123.
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Clinical Benefit from Ipilimumab Therapy in Melanoma Patients may be Associated with Serum CTLA4 Levels. Front Oncol. 2014; 4:110. Leung AM, Lee AF, Ozao-Choy J, Ramos RI, Hamid O, O'Day SJ, Shin-Sim M, Morton DL, Faries MB, Sieling PA, Lee DJ. PMID: 24904825; PMCID: PMC4032905.
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Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells. Immunology. 2014 Feb; 141(2):174-80. Schenk M, Fabri M, Krutzik SR, Lee DJ, Vu DM, Sieling PA, Montoya D, Liu PT, Modlin RL. PMID: 24032597; PMCID: PMC3904238.
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Microbial dysbiosis is associated with human breast cancer. PLoS One. 2014; 9(1):e83744. Xuan C, Shamonki JM, Chung A, Dinome ML, Chung M, Sieling PA, Lee DJ. PMID: 24421902; PMCID: PMC3885448.
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Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science. 2013 Mar 22; 339(6126):1448-53. Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. PMID: 23449998; PMCID: PMC3653587.
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Immune correlates of melanoma survival in adoptive cell therapy. Oncoimmunology. 2013 Feb 01; 2(2):e22889. Lee AF, Sieling PA, Lee DJ. PMID: 23525606; PMCID: PMC3601160.
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Galectin-3 regulates the innate immune response of human monocytes. J Infect Dis. 2013 Mar 15; 207(6):947-56. Chung AW, Sieling PA, Schenk M, Teles RM, Krutzik SR, Hsu DK, Liu FT, Sarno EN, Rea TH, Stenger S, Modlin RL, Lee DJ. PMID: 23255567; PMCID: PMC3571442.
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Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice. PLoS Pathog. 2012; 8(11):e1003047. Cho JS, Guo Y, Ramos RI, Hebroni F, Plaisier SB, Xuan C, Granick JL, Matsushima H, Takashima A, Iwakura Y, Cheung AL, Cheng G, Lee DJ, Simon SI, Miller LS. PMID: 23209417; PMCID: PMC3510260.
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Combined intralesional Bacille Calmette-Guérin (BCG) and topical imiquimod for in-transit melanoma. J Immunother. 2012 Nov-Dec; 35(9):716-20. Kidner TB, Morton DL, Lee DJ, Hoban M, Foshag LJ, Turner RR, Faries MB. PMID: 23090081; PMCID: PMC3674843.
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Genetic profiling of BRAF inhibitor-induced keratoacanthomas reveals no induction of MAP kinase pathway expression. J Invest Dermatol. 2013 Mar; 133(3):830-833. Kulkarni RP, Plaisier S, Ra SH, Li X, Lee DJ, Hillman JD, Binder SW. PMID: 23014342.
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NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med. 2012 Mar 25; 18(4):555-63. Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. PMID: 22447076; PMCID: PMC3348859.
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A role for interleukin-5 in promoting increased immunoglobulin M at the site of disease in leprosy. Immunology. 2010 Nov; 131(3):405-14. Ochoa MT, Teles R, Haas BE, Zaghi D, Li H, Sarno EN, Rea TH, Modlin RL, Lee DJ. PMID: 20561085; PMCID: PMC2996561.
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Integrated pathways for neutrophil recruitment and inflammation in leprosy. J Infect Dis. 2010 Feb 15; 201(4):558-69. Lee DJ, Li H, Ochoa MT, Tanaka M, Carbone RJ, Damoiseaux R, Burdick A, Sarno EN, Rea TH, Modlin RL. PMID: 20070238; PMCID: PMC2811231.
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Vitiligo in an urban academic setting. Int J Dermatol. 2010 Jan; 49(1):39-43. Paravar T, Lee DJ. PMID: 20465609.
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Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe. 2009 Oct 22; 6(4):343-53. Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, Cheng G, Modlin RL. PMID: 19837374; PMCID: PMC2764558.
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Activation of Fc gamma RI on monocytes triggers differentiation into immature dendritic cells that induce autoreactive T cell responses. J Immunol. 2009 Aug 15; 183(4):2349-55. Tanaka M, Krutzik SR, Sieling PA, Lee DJ, Rea TH, Modlin RL. PMID: 19635920; PMCID: PMC2790276.
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DNA transportation authority. Nat Med. 2008 Dec; 14(12):1319-20. Lee DJ, Modlin RL. PMID: 19057557; PMCID: PMC2772991.
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Thalidomide: mechanisms of action. Int Rev Immunol. 2008; 27(3):111-35. Paravar T, Lee DJ. PMID: 18437602.
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LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. J Immunol. 2007 Dec 15; 179(12):8128-36. Lee DJ, Sieling PA, Ochoa MT, Krutzik SR, Guo B, Hernandez M, Rea TH, Cheng G, Colonna M, Modlin RL. PMID: 18056355; PMCID: PMC2650749.
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Angiogenesis in cutaneous lesions of leprosy: implications for treatment. Arch Dermatol. 2007 Dec; 143(12):1527-9. Bhandarkar SS, Cohen C, Kuruvila M, Rea TH, Mackelfresh JB, Lee DJ, Modlin RL, Arbiser JL. PMID: 18087002.
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Breaking tolerance--another piece added to the vitiligo puzzle. J Invest Dermatol. 2005 Jan; 124(1):xiii-xv. Lee DJ, Modlin RL. PMID: 15654945.
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Update on pathogenesis and treatment of acne. Curr Opin Pediatr. 2003 Aug; 15(4):405-10. Lee DJ, Van Dyke GS, Kim J. PMID: 12891054.
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