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Computational discovery of precision therapeutics for hidradenitis suppurativa. bioRxiv. 2026 Feb 24. Lee EY, Leboit P, Naik HB, Tang AS, Vallania F, Yates AE, Klufas DM, Hansen SL, Rosenblum MD, Lowe MM, Sirota M. PMID: 41799800; PMCID: PMC12964703.
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Artificial intelligence-enabled precision medicine for inflammatory skin diseases. J Invest Dermatol. 2026 Feb 14. Tang AS, Wei ML, Haemel A, La C, Sirota M, Lee EY. PMID: 41689579; PMCID: PMC13005173.
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First, do NOHARM: towards clinically safe large language models. ArXiv. 2025 Dec 17. Wu D, Haredasht FN, Maharaj SK, Jain P, Tran J, Gwiazdon M, Rustagi A, Jindal J, Koshy JM, Kadiyala V, Agarwal A, Tappuni B, French B, Jesudasen S, Cosgriff CV, Chakraborty R, Caldwell J, Ziolkowski S, Iberri DJ, Diep R, Dalal RS, Newman KL, Galetta K, Pallais JC, Wei N, Buchheit KM, Hong DI, Lee EY, Shih A, Pahalyants V, Kaplan TB, Ravi V, Khemani S, Liang AS, Shirvani D, Patil A, Marshall N, Chopra K, Koh J, Badhwar A, McCoy LG, Wu DJH, Weng Y, Ranji S, Schulman K, Shah NH, Hom J, Milstein A, Rodman A, Chen JH, Goh E. PMID: 41532042; PMCID: PMC12794822.
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Dynamics of Th1/Th17 responses and antimicrobial pathways in leprosy skin lesions. J Clin Invest. 2025 Sep 02; 135(17). Andrade PR, Ma F, Lu J, de Anda J, Lee EY, Agak GW, Dobry CJ, de Andrade Silva BJ, Teles RM, Mansky LA, Perrie J, Montoya DJ, Bryson BD, Gudjonsson JE, Wong GC, Sarno EN, Pellegrini M, Modlin RL. PMID: 40569678; PMCID: PMC12404764.
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Chemokines kill bacteria without triggering antimicrobial resistance by binding anionic phospholipids. Sci Adv. 2025 Jun 06; 11(23):eads2675. Pontejo SM, Martinez S, Zhao A, Barnes K, de Anda J, Alimohamadi H, Lee EY, Dishman AF, Volkman BF, Wong GCL, Garboczi DN, Ballesteros A, Murphy PM. PMID: 40479071; PMCID: PMC12143392.
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Artificial intelligence-enabled precision medicine for inflammatory skin diseases. ArXiv. 2025 May 14. Tang A, Wei ML, Haemel A, La C, Sirota M, Lee EY. PMID: 40463698; PMCID: PMC12133082.
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Transcriptomic analysis reveals immune signatures associated with specific cutaneous manifestations of lupus in systemic lupus erythematosus. bioRxiv. 2025 Apr 29. Lee EY, Patterson S, Cutts Z, Lanata CM, Dall'Era M, Yazdany J, Criswell LA, Haemel A, Katz P, Jimmie Ye C, Langelier C, Sirota M. PMID: 40488128; PMCID: PMC12143873.
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The p12 Subunit Choreographs the Regulation and Functions of Two Forms of DNA Polymerase δ in Mammalian Cells. Genes (Basel). 2025 Feb 03; 16(2). Xu D, Ayyamperumal S, Zhang S, Chen J, Lee EYC, Lee MYWT. PMID: 40004517; PMCID: PMC11855201.
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Emerging Techniques in Spatial Multiomics: Fundamental Principles and Applications to Dermatology. J Invest Dermatol. 2025 May; 145(5):1017-1032. Jia BB, Sun BK, Lee EY, Ren B. PMID: 39503694; PMCID: PMC13003203.
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Chemokines Kill Bacteria by Binding Anionic Phospholipids without Triggering Antimicrobial Resistance. bioRxiv. 2024 Jul 25. Pontejo SM, Martinez S, Zhao A, Barnes K, de Anda J, Alimohamadi H, Lee EY, Dishman AF, Volkman BF, Wong GCL, Garboczi DN, Ballesteros A, Murphy PM. PMID: 39091850; PMCID: PMC11291121.
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Age and urban-rural disparities in cutaneous melanoma mortality rates in the United States during the COVID-19 pandemic. Pigment Cell Melanoma Res. 2024 11; 37(6):783-792. Hu T, Ma Z, Guo Y, Qiu S, Lv F, Liu Y, Ng WH, Zu J, Yeo YH, Ji F, Lee EY, Li Z. PMID: 38868930.
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Sweet syndrome in a patient with rectal adenocarcinoma and HIV following neoadjuvant chemoradiation. JAAD Case Rep. 2024 Jan; 43:72-75. Wilkerson K, Bradley FE, Lee EY, Cohen JN, Chang AY. PMID: 38234372; PMCID: PMC10793161.
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The DHX9 helicase interacts with human DNA polymerase δ4 and stimulates its activity in D-loop extension synthesis. DNA Repair (Amst). 2023 08; 128:103513. Wang X, Zhang S, Zhang Z, Mazloum NA, Lee EYC, Lee MYW. PMID: 37285751; PMCID: PMC10330758.
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Excess psoriasis and psoriatic arthritis mortality during the COVID-19 pandemic in the United States: A nationwide population-based study from 2010 to 2021. J Eur Acad Dermatol Venereol. 2023 Jun; 37(6):1221-1227. Liu Y, He X, Lee EY, Lv F, Yao L, Meng Q, Zhang L, Ng WH, Zhang Y, Elias PM, Man M, Yeo YH, Li Z. PMID: 36808772.
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Severe recurrence of reactive infectious mucocutaneous eruption with extensive ocular involvement in an adult due to SARS-CoV-2. JAAD Case Rep. 2023 Jun; 36:1-3. Wu D, Lee EY, Lifton J, Zullo SW, Seiger K, Nadadur R, Fox LP, Escobar DJ, Dobry AS, Yung M, Kangelaris KN, Arakaki RY. PMID: 36819988; PMCID: PMC9931421.
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POLDIP3: At the Crossroad of RNA and DNA Metabolism. Genes (Basel). 2022 10 22; 13(11). Singh M, Zhang S, Perez AM, Lee EYC, Lee MYWT, Zhang D. PMID: 36360158; PMCID: PMC9690394.
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DNA polymerase delta interacting protein 3 facilitates the activation and maintenance of DNA damage checkpoint in response to replication stress. Animal Model Exp Med. 2022 10; 5(5):461-469. Zhang S, Lee EYC, Lee MYWT, Zhang D. PMID: 36168146; PMCID: PMC9610138.
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Phenol-Soluble Modulins From Staphylococcus aureus Biofilms Form Complexes With DNA to Drive Autoimmunity. Front Cell Infect Microbiol. 2022; 12:884065. Grando K, Nicastro LK, Tursi SA, De Anda J, Lee EY, Wong GCL, Tükel Ç. PMID: 35646719; PMCID: PMC9131096.
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Histidine-Mediated Ion Specific Effects Enable Salt Tolerance of a Pore-Forming Marine Antimicrobial Peptide. Angew Chem Int Ed Engl. 2022 06 20; 61(25):e202108501. Xian W, Hennefarth MR, Lee MW, Do T, Lee EY, Alexandrova AN, Wong GCL. PMID: 35352449; PMCID: PMC9189074.
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Quantitative readability analysis of online patient educational materials for dermatofibrosarcoma protuberans. Int J Dermatol. 2022 05; 61(5):e196-e197. Kirchner A, Patel M, Kulkarni V, Usman A, Lee EY. PMID: 34165781; PMCID: PMC12993426.
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Readability assessment of patient-facing online educational content for pyoderma gangrenosum. J Am Acad Dermatol. 2022 05; 86(5):1127-1128. Kirchner A, Kulkarni V, Rajkumar J, Usman A, Hassan S, Lee EY. PMID: 33882279; PMCID: PMC13008337.
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PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain. Proc Natl Acad Sci U S A. 2021 01 05; 118(1). Lee EY, Chan LC, Wang H, Lieng J, Hung M, Srinivasan Y, Wang J, Waschek JA, Ferguson AL, Lee KF, Yount NY, Yeaman MR, Wong GCL. PMID: 33372152; PMCID: PMC7817161.
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Ocular lichen planus treated with lifitegrast. Int J Dermatol. 2021 Jun; 60(6):e231-e233. Lee EY, Arzeno J, Ni C, Holland V. PMID: 32989726; PMCID: PMC12959925.
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Discovery of Novel Type II Bacteriocins Using a New High-Dimensional Bioinformatic Algorithm. Front Immunol. 2020; 11:1873. Yount NY, Weaver DC, de Anda J, Lee EY, Lee MW, Wong GCL, Yeaman MR. PMID: 33013838; PMCID: PMC7494827.
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Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation. Front Immunol. 2020; 11:1629. Lee EY, Srinivasan Y, de Anda J, Nicastro LK, Tükel Ç, Wong GCL. PMID: 32849553; PMCID: PMC7412598.
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Standing electric scooter injuries: Impact on a community. Am J Surg. 2021 01; 221(1):227-232. Bloom MB, Noorzad A, Lin C, Little M, Lee EY, Margulies DR, Torbati SS. PMID: 32778397; PMCID: PMC7933485.
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Machine learning for precision dermatology: Advances, opportunities, and outlook. J Am Acad Dermatol. 2021 May; 84(5):1458-1459. Lee EY, Maloney NJ, Cheng K, Bach DQ. PMID: 32645400; PMCID: PMC8023050.
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Telehealth Solutions for In-hospital Communication with Patients Under Isolation During COVID-19. West J Emerg Med. 2020 Jun 23; 21(4):801-806. Fang J, Liu YT, Lee EY, Yadav K. PMID: 32726245; PMCID: PMC7390554.
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Switchable Membrane Remodeling and Antifungal Defense by Metamorphic Chemokine XCL1. ACS Infect Dis. 2020 05 08; 6(5):1204-1213. Dishman AF, Lee MW, de Anda J, Lee EY, He J, Huppler AR, Wong GCL, Volkman BF. PMID: 32243126; PMCID: PMC7258946.
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Circulating biomarkers predictive of tumor response to cancer immunotherapy. Expert Rev Mol Diagn. 2019 10; 19(10):895-904. Lee EY, Kulkarni RP. PMID: 31469965; PMCID: PMC6773262.
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Improved prediction of HIT in the SICU using an improved model of the Warkentin 4-T system: 3-T. Am J Surg. 2020 01; 219(1):54-57. Bloom MB, Johnson J, Volod O, Lee EY, White T, Margulies DR. PMID: 31400811; PMCID: PMC6917902.
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Two forms of human DNA polymerase δ: Who does what and why? DNA Repair (Amst). 2019 09; 81:102656. Lee MYWT, Zhang S, Wang X, Chao HH, Zhao H, Darzynkiewicz Z, Zhang Z, Lee EYC. PMID: 31326365.
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Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature. 2019 05; 569(7755):236-240. Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. PMID: 31043745; PMCID: PMC6716525.
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CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis. Nat Commun. 2019 05 01; 10(1):1731. Lande R, Lee EY, Palazzo R, Marinari B, Pietraforte I, Santos GS, Mattenberger Y, Spadaro F, Stefanantoni K, Iannace N, Dufour AM, Falchi M, Bianco M, Botti E, Bianchi L, Alvarez M, Riccieri V, Truchetet ME, C L Wong G, Chizzolini C, Frasca L. PMID: 31043596; PMCID: PMC6494823.
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Off-label studies on apremilast in dermatology: a review. J Dermatolog Treat. 2020 Mar; 31(2):131-140. Maloney NJ, Zhao J, Tegtmeyer K, Lee EY, Cheng K. PMID: 30935262; PMCID: PMC6774908.
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Unifying structural signature of eukaryotic α-helical host defense peptides. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):6944-6953. Yount NY, Weaver DC, Lee EY, Lee MW, Wang H, Chan LC, Wong GCL, Yeaman MR. PMID: 30877253; PMCID: PMC6452647.
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Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9. Nat Commun. 2019 03 04; 10(1):1012. Lee EY, Zhang C, Di Domizio J, Jin F, Connell W, Hung M, Malkoff N, Veksler V, Gilliet M, Ren P, Wong GCL. PMID: 30833557; PMCID: PMC6399285.
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Machine learning antimicrobial peptide sequences: Some surprising variations on the theme of amphiphilic assembly. Curr Opin Colloid Interface Sci. 2018 Nov; 38:204-213. Lee MW, Lee EY, Ferguson AL, Wong GCL. PMID: 31093008; PMCID: PMC6513345.
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Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties. Cancer Biol Ther. 2019; 20(4):474-486. Mishra B, Zhang S, Zhao H, Darzynkiewicz Z, Lee EYC, Lee MYWT, Zhang Z. PMID: 30427259; PMCID: PMC6422523.
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Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis. iScience. 2018 Aug 31; 6:52-67. Peddu C, Zhang S, Zhao H, Wong A, Lee EYC, Lee MYWT, Zhang Z. PMID: 30240625; PMCID: PMC6137289.
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What Can Pleiotropic Proteins in Innate Immunity Teach Us about Bioconjugation and Molecular Design? Bioconjug Chem. 2018 07 18; 29(7):2127-2139. Lee MW, Lee EY, Wong GCL. PMID: 29771496; PMCID: PMC6540093.
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Multigenerational memory and adaptive adhesion in early bacterial biofilm communities. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):4471-4476. Lee CK, de Anda J, Baker AE, Bennett RR, Luo Y, Lee EY, Keefe JA, Helali JS, Ma J, Zhao K, Golestanian R, O'Toole GA, Wong GCL. PMID: 29559526; PMCID: PMC5924909.
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Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors. Sci Rep. 2018 03 05; 8(1):4032. Takahashi T, Kulkarni NN, Lee EY, Zhang LJ, Wong GCL, Gallo RL. PMID: 29507358; PMCID: PMC5838106.
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Modulation of toll-like receptor signaling by antimicrobial peptides. Semin Cell Dev Biol. 2019 04; 88:173-184. Lee EY, Lee MW, Wong GCL. PMID: 29432957; PMCID: PMC6087683.
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Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission. ACS Cent Sci. 2017 Nov 22; 3(11):1156-1167. Lee MW, Lee EY, Lai GH, Kennedy NW, Posey AE, Xian W, Ferguson AL, Hill RB, Wong GCL. PMID: 29202017; PMCID: PMC5704292.
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What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning? Interface Focus. 2017 Dec 06; 7(6):20160153. Lee EY, Lee MW, Fulan BM, Ferguson AL, Wong GCL. PMID: 29147555; PMCID: PMC5665795.
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Crystallinity of Double-Stranded RNA-Antimicrobial Peptide Complexes Modulates Toll-Like Receptor 3-Mediated Inflammation. ACS Nano. 2017 12 26; 11(12):12145-12155. Lee EY, Takahashi T, Curk T, Dobnikar J, Gallo RL, Wong GCL. PMID: 29016111; PMCID: PMC5936640.
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High-Speed "4D" Computational Microscopy of Bacterial Surface Motility. ACS Nano. 2017 09 26; 11(9):9340-9351. de Anda J, Lee EY, Lee CK, Bennett RR, Ji X, Soltani S, Harrison MC, Baker AE, Luo Y, Chou T, O'Toole GA, Armani AM, Golestanian R, Wong GCL. PMID: 28836761; PMCID: PMC5978429.
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Regulation and Modulation of Human DNA Polymerase δ Activity and Function. Genes (Basel). 2017 Jul 24; 8(7). Lee MYWT, Wang X, Zhang S, Zhang Z, Lee EYC. PMID: 28737709; PMCID: PMC5541323.
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Machine learning-enabled discovery and design of membrane-active peptides. Bioorg Med Chem. 2018 06 01; 26(10):2708-2718. Lee EY, Wong GCL, Ferguson AL. PMID: 28728899; PMCID: PMC5758442.
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A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity. J Innate Immun. 2017; 9(5):456-463. Stolzenberg E, Berry D, Lee EY, Kroemer A, Kaufman S, Wong GCL, Oppenheim JJ, Sen S, Fishbein T, Bax A, Harris B, Barbut D, Zasloff MA. PMID: 28651250; PMCID: PMC5865636.
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Direct Antimicrobial Activity of IFN-β. J Immunol. 2017 05 15; 198(10):4036-4045. Kaplan A, Lee MW, Wolf AJ, Limon JJ, Becker CA, Ding M, Murali R, Lee EY, Liu GY, Wong GCL, Underhill DM. PMID: 28411186; PMCID: PMC5469413.
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Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9. PLoS Pathog. 2017 Apr; 13(4):e1006315. Tursi SA, Lee EY, Medeiros NJ, Lee MH, Nicastro LK, Buttaro B, Gallucci S, Wilson RP, Wong GCL, Tükel Ç. PMID: 28410407; PMCID: PMC5406031.
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Mapping membrane activity in undiscovered peptide sequence space using machine learning. Proc Natl Acad Sci U S A. 2016 11 29; 113(48):13588-13593. Lee EY, Fulan BM, Wong GC, Ferguson AL. PMID: 27849600; PMCID: PMC5137689.
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S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. PLoS Pathog. 2016 06; 12(6):e1005705. Realegeno S, Kelly-Scumpia KM, Dang AT, Lu J, Teles R, Liu PT, Schenk M, Lee EY, Schmidt NW, Wong GC, Sarno EN, Rea TH, Ochoa MT, Pellegrini M, Modlin RL. PMID: 27355424; PMCID: PMC4927120.
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Oxidation of Membrane Curvature-Regulating Phosphatidylethanolamine Lipid Results in Formation of Bilayer and Cubic Structures. Langmuir. 2016 Mar 15; 32(10):2450-7. Sankhagowit S, Lee EY, Wong GC, Malmstadt N. PMID: 26866900; PMCID: PMC6559366.
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A review of immune amplification via ligand clustering by self-assembled liquid-crystalline DNA complexes. Adv Colloid Interface Sci. 2016 06; 232:17-24. Lee EY, Lee CK, Schmidt NW, Jin F, Lande R, Curk T, Frenkel D, Dobnikar J, Gilliet M, Wong GCL. PMID: 26956527; PMCID: PMC6519935.
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PDIP46 (DNA polymerase δ interacting protein 46) is an activating factor for human DNA polymerase δ. Oncotarget. 2016 Feb 02; 7(5):6294-313. Wang X, Zhang S, Zheng R, Yue F, Lin SH, Rahmeh AA, Lee EY, Zhang Z, Lee MY. PMID: 26819372; PMCID: PMC4868757.
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Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase δ revealed in individual cells by cytometry. Oncotarget. 2015 May 20; 6(14):11735-50. Darzynkiewicz Z, Zhao H, Zhang S, Lee MY, Lee EY, Zhang Z. PMID: 26059433; PMCID: PMC4494901.
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The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression. Cell Cycle. 2014; 13(1):23-31. Lee MY, Zhang S, Lin SH, Wang X, Darzynkiewicz Z, Zhang Z, Lee EY. PMID: 24300032; PMCID: PMC3925730.
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PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2. Cell Cycle. 2013 Oct 01; 12(19):3184-93. Wong A, Zhang S, Mordue D, Wu JM, Zhang Z, Darzynkiewicz Z, Lee EY, Lee MY. PMID: 23989611; PMCID: PMC3865014.
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A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. J Biol Chem. 2013 Oct 11; 288(41):29550-61. Zhang S, Zhao H, Darzynkiewicz Z, Zhou P, Zhang Z, Lee EY, Lee MY. PMID: 23913683; PMCID: PMC3795253.
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Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage. J Biol Chem. 2013 Feb 01; 288(5):2941-50. Zhang S, Zhou Y, Sarkeshik A, Yates JR, Thomson TM, Zhang Z, Lee EY, Lee MY. PMID: 23233665; PMCID: PMC3561517.
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Regulation of human DNA polymerase delta in the cellular responses to DNA damage. Environ Mol Mutagen. 2012 Dec; 53(9):683-98. Lee MY, Zhang S, Lin SH, Chea J, Wang X, LeRoy C, Wong A, Zhang Z, Lee EY. PMID: 23047826.
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Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage. Cell Cycle. 2012 Aug 01; 11(15):2885-95. Chea J, Zhang S, Zhao H, Zhang Z, Lee EY, Darzynkiewicz Z, Lee MY. PMID: 22801543; PMCID: PMC3419061.
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Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in the MultiBac system. PLoS One. 2012; 7(6):e39156. Zhou Y, Meng X, Zhang S, Lee EY, Lee MY. PMID: 22723953; PMCID: PMC3377666.
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Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation. Cell Cycle. 2012 Jun 01; 11(11):2128-36. Zhang Z, Zhang S, Lin SH, Wang X, Wu L, Lee EY, Lee MY. PMID: 22592530; PMCID: PMC3368864.
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P50, the small subunit of DNA polymerase delta, is required for mediation of the interaction of polymerase delta subassemblies with PCNA. PLoS One. 2011; 6(11):e27092. Wang Y, Zhang Q, Chen H, Li X, Mai W, Chen K, Zhang S, Lee EY, Lee MY, Zhou Y. PMID: 22073260; PMCID: PMC3206906.
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Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. PLoS One. 2011; 6(7):e22224. Zhou Y, Chen H, Li X, Wang Y, Chen K, Zhang S, Meng X, Lee EY, Lee MY. PMID: 21789240; PMCID: PMC3137619.
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The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis. Biochemistry. 2010 May 04; 49(17):3545-54. Meng X, Zhou Y, Lee EY, Lee MY, Frick DN. PMID: 20334433; PMCID: PMC2860660.
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DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers. Nucleic Acids Res. 2009 Feb; 37(2):647-57. Meng X, Zhou Y, Zhang S, Lee EY, Frick DN, Lee MY. PMID: 19074196; PMCID: PMC2632934.
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PCNA is ubiquitinated by RNF8. Cell Cycle. 2008 Nov 01; 7(21):3399-404. Zhang S, Chea J, Meng X, Zhou Y, Lee EY, Lee MY. PMID: 18948756.
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Identification of the interaction sites of Inhibitor-3 for protein phosphatase-1. Biochem Biophys Res Commun. 2008 Dec 12; 377(2):710-713. Zhang L, Qi Z, Gao Y, Lee EYC. PMID: 18951879; PMCID: PMC2613339.
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Protein phosphatase-1 is targeted to DNA polymerase delta via an interaction with the p68 subunit. Biochemistry. 2008 Oct 28; 47(43):11367-76. Gao Y, Zhou Y, Xie B, Zhang S, Rahmeh A, Huang HS, Lee MY, Lee EY. PMID: 18826257.
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Protein phosphatase-1 inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response. J Biol Chem. 2008 Jun 27; 283(26):18135-46. Huang HS, Lee EY. PMID: 18450750; PMCID: PMC2440612.
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A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta. J Biol Chem. 2007 May 25; 282(21):15330-40. Zhang S, Zhou Y, Trusa S, Meng X, Lee EY, Lee MY. PMID: 17317665.
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Functional roles of p12, the fourth subunit of human DNA polymerase delta. J Biol Chem. 2006 May 26; 281(21):14748-55. Li H, Xie B, Zhou Y, Rahmeh A, Trusa S, Zhang S, Gao Y, Lee EY, Lee MY. PMID: 16510448.
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Protein phosphatase-1 inhibitor-3 is co-localized to the nucleoli and centrosomes with PP1gamma1 and PP1alpha, respectively. Arch Biochem Biophys. 2005 Nov 15; 443(1-2):33-44. Huang HS, Pozarowski P, Gao Y, Darzynkiewicz Z, Lee EY. PMID: 16256067.
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