7 results found
https://www.frontiersin.org/articles/10.3389/fnins.2023.1257056/full

…mined whether embryonic expression of 4E-BP1 CA in cortical pyramidal neurons prevents mTORC1-induced seizures using the Rheb CA mouse model. We co-expressed Rheb CA with 4E-BP1 CA , which was previously shown to reduce cap-dependent translation ( Lin et al., 2016 ; Nguyen et al.…