6 results found
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117434

…own that PTPN11 pathogenic variants cause diverse human disorders and can drive events that lead to pediatric malignancies. Furthermore, pathogenic variants can variably perturb intracellular signaling, both qualitatively and quantitatively. Importantly, the discovery of PTPN11 i…