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Timeliness of Care for Transferred and Directly Admitted Patients With Anticoagulation-Associated Intracerebral Hemorrhage. J Am Heart Assoc. 2026 Feb 17; 15(4):e043223. Royan R, Saver JL, Solomon N, Alhanti B, Stamm B, Messe SR, Xian Y, Bhatt DL, Chang RC, Danelich I, Huang J, Schwamm LH, Smith EE, Goldstein JN, Grory BM, de Havenon AH, Fonarow GC, Sheth KN. PMID: 41703701.
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Tenecteplase for Acute Non-Large Vessel Occlusion 4.5 to 24 Hours After Ischemic Stroke: The OPTION Randomized Clinical Trial. JAMA. 2026 Feb 05. Ma G, Mo R, Zuo Y, Ma Q, Zhao G, Yao X, Liang J, Zhou L, He Y, Long F, Yuan Z, Liu L, Han G, Tan Y, Ai Z, Cai C, Liu J, Zhang L, Yang H, Yi T, Li L, Fu Y, Zhang Y, Shao X, Yu Z, Wu S, Du Y, Mao L, Guo H, Chen X, Chen Y, Zhao Q, Chi L, Liu Y, Zhang H, Li G, Meng S, Wu Y, Wu J, Jiang Z, Lei S, Gao D, Zhong L, Fiehler J, Wang D, Nguyen TN, Saver JL, Hao J, OPTION Investigators. PMID: 41642827; PMCID: PMC12878635.
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Endovascular vs Medical Treatment of Basilar Artery Occlusion: 3-Year Outcomes of the ATTENTION Randomized Clinical Trial. JAMA Neurol. 2026 Feb 01; 83(2):107-114. Hu W, Tao C, Li R, Chen Z, Chen W, Yi T, Wang H, Zhou P, Cao Z, Zeng G, Cui T, Su J, Chen L, Wang G, Sun J, Zhu Y, Wang L, Zhang C, Liu T, Song J, Jing X, Wang A, Wang J, Xu P, Luo C, Qureshi AI, AbdalKader M, Nguyen TN, Saver JL, Nogueira RG, Liu X. PMID: 41460644; PMCID: PMC12750332.
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Door-in-door-out times and outcomes in patients with acute ischaemic stroke transferred for endovascular therapy in the USA: a retrospective cohort study. Lancet Neurol. 2026 Feb; 25(2):160-169. Royan R, Stamm B, Giurcanu M, Messe SR, Jauch EC, Saver JL, Prabhakaran S. PMID: 41579902.
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Framework for developing intracerebral haemorrhage recognition scales and technologies for hyperacute prehospital blood pressure lowering. Stroke Vasc Neurol. 2026 Jan 29. Taleb S, Hsu J, Saver JL. PMID: 41611345.
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A CT imaging-based prediction model of functional outcome and benefit of endovascular thrombectomy for ischemic stroke. Eur Radiol. 2026 Jan 14. Luijten SP, Ganesh A, Marcus AP, Bentley P, Rueckert D, Brown S, Benali F, Fladt J, Bala F, Alhabli I, Muir KW, Saver J, Demchuk AM, Jovin TG, Bracard S, Campbell BC, Guillemin F, White P, Hill MD, Mitchell PJ, Majoie CB, Goyal M, Dippel DW, van der Lugt A, van Walsum T, Lingsma HF, Bos D. PMID: 41533062.
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Endovascular Therapy versus Medical Management for Basilar Artery Occlusion Presenting beyond 24 Hours. Radiology. 2026 Jan; 318(1):e250734. Tao C, Hu T, Chen Z, Wang H, Cui T, Chen W, Yi T, Mei B, Wang E, Zhu Y, Li R, Sun J, Hu H, Wang L, Zhang C, Liu T, Song J, Jing X, Qureshi AI, Abdalkader M, Nguyen TN, Nogueira RG, Saver JL, Hu W. PMID: 41528228.
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Rationale, design and baseline characteristics of participants in the OCEANIC-STROKE trial of FXIa inhibition for secondary stroke prevention. Eur Stroke J. 2026 Jan 01; 11(1). Sharma M, Dong Q, Hirano T, Kasner SE, Saver J, Masjuan J, Demchuk AM, Cordonnier C, Bereczki D, Tsivgoulis G, Veltkamp R, Staikov I, Bae HJ, Campbell BCV, Zini A, Lee IH, Ameriso S, Kovar M, Mikulik R, Lemmens R, Ferro JM, Robinson T, Christensen H, Ozturk S, Leker RR, Turcani P, Slowik A, Amaya P, Hoo FK, De Marchis GM, Knoflach M, Sylaja PN, Putaala J, Coutinho JM, Worp HBV, Miglane E, Matijosaitis V, Lindgren AG, Silva GS, Sandset EC, Turuspekova ST, Joundi RA, Schulze K, Shestakovska O, Gilbride J, Bangdiwala SI, Xu L, Muehlhofer E, Colorado P, Mundl H, Keller L, Shoamanesh A. PMID: 41614533; PMCID: PMC12866625.
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Race- and Ethnicity-Specific Hospital Arrival and Emergency Medicine Service Activation Times by US State for Ischemic Stroke. J Am Heart Assoc. 2026 Jan 06; 15(1):e041674. Man S, Sun JL, Alhanti B, Mac Grory B, Smith EE, Schwamm LH, Bhatt DL, Saver JL, Xian Y, Uchino K, Fonarow GC. PMID: 41467391; PMCID: PMC12908999.
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Intravenous Thrombolysis in Patients on Direct Oral Anticoagulants: Analysis of the Get With The Guidelines Stroke Registry. J Am Heart Assoc. 2026 Jan 06; 15(1):e044321. Yaghi S, Shu L, Mistry EA, Adeoye O, Schwamm L, Messe S, Elkind MSV, Ghannam M, de Havenon A, Furie K, Xian Y, Streib C, Wangqin R, Henninger N, Saver JL, Smith EE. PMID: 41467386; PMCID: PMC12909014.
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Effect of Rurality on Global Access to Mechanical Thrombectomy: A Subanalysis of the MT-GLASS Study. Stroke. 2026 Mar; 57(3):770-778. Asif KS, Aroor SR, Otite FO, Desai SM, Singh N, Patel S, Dmytriw AA, Budohoski K, Crowe JR, Krothapalli N, Dawod G, Jagolino-Cole AL, Jadhav AP, Zachrison KS, Ortega-Gutierrez S, Saver JL, Yavagal DR, Al-Mufti F, Society of Vascular and Interventional Neurology Mission Thrombectomy Global Executive Committee. PMID: 41410045.
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Changes in Oxygen Metabolism Biomarkers of Ischemic Tissue Treated With Electrical Stimulation. Stroke Vasc Interv Neurol. 2026 Jan; 6(1):e002094. Bahr-Hosseini M, Asghariahmadabad M, Bikson M, Saver JL, Liebeskind DS, Nael K. PMID: 41503089; PMCID: PMC12772432.
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Differential Effects of Admission Hemoglobin A1c by Estimated Glomerular Filtration Rate Stages on Mortality in Acute Ischemic Stroke and Diabetes. J Am Heart Assoc. 2025 Dec 16; 14(24):e044112. Kim JT, Lee JS, Kim H, Kim BJ, Kang J, Lee KJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Park TH, Lee K, Lee JY, Lee J, Kwon DH, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Lee M, Kim DE, Gwak DS, Choi JC, Kwon JH, Kim WJ, Shin DI, Yum KS, Sohn SI, Hong JH, Park H, Lee SH, Kim C, Park MS, Ryu WS, Park KY, Heo SH, Lee J, Saver JL, Bae HJ. PMID: 41378485; PMCID: PMC12826925.
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Impact of thrombectomy techniques on outcome in medium or distal vessel occlusion: subanalysis of the DISTAL Trial. J Neurointerv Surg. 2025 Dec 03. Schulze-Zachau V, Rommers N, Dobrocky T, Hajdu SD, Fiehler J, Fragata I, Gralla J, Machi P, Kirschke JS, van Es ACGM, Kaesmacher J, Buhk JH, Saver JL, Martínez-Galdámez M, Piechowiak EII, Kaiser DPO, Tancredi I, Van Den Bergh F, Hellstern V, Khanafer A, Volders D, Strbian D, Ribo M, Karwacki GM, Aebischer V, Brehm A, Fischer U, Psychogios MN, Collaborators D. PMID: 41339078.
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Is the modified Rankin Scale still the right endpoint for neurointerventional trials? J Neurointerv Surg. 2025 Nov 18; 17(12):1267-1269. Inoa V, Goyal N, Saver JL, Goyal M. PMID: 41253446.
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Efficacy and Safety of Very Low Achieved LDL Cholesterol in Patients With Previous Ischemic Stroke. Circulation. 2026 Jan 13; 153(2):86-93. Monguillon V, Kelly PJ, O'Donoghue ML, Park JG, Bohula EA, Saver JL, Atar D, Keech AC, Sever PS, Wang H, Paiva da Silva Lima G, Sabatine MS, Giugliano RP. PMID: 41178569.
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Endovascular Thrombectomy versus Standard Medical Management in Treatment of Acute Medium Vessel Occlusion Strokes: A Multicenter Registry. Radiology. 2025 Nov; 317(2):e251040. Jing X, Chen Z, Zhao Y, Yi T, Wang H, Nguyen TN, Abdalkader M, Tao C, Yang H, Li R, Zhu Y, Wang L, Zhang C, Liu T, Song J, Li D, Qureshi AI, Saver JL, Nogueira RG, Hu W. PMID: 41288486.
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Association of Component Strategies of the Target Stroke Phase 3 Nationwide Quality Improvement Program With Accelerated Door-to-Puncture and Door-In-Door-Out Times for Ischemic Stroke Endovascular Thrombectomy in the United States. Circ Cardiovasc Qual Outcomes. 2025 Nov; 18(11):e012456. Mac Grory B, Asif KS, Xu H, Alhanti B, B Lusk J, Hasan D, Park S, Boehme AK, Zachrison KS, Goyal M, Southerland AM, Jadhav A, Ortega Gutierrez S, Hassan A, Fargen K, Sheth KN, Jauch EC, Xian Y, Peterson ED, Smith EE, Messe SR, Schwamm LH, Panagos P, Wira C, Saver JL, Fonarow GC. PMID: 41111412; PMCID: PMC12616356.
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Electromagnetic Stimulation to Reduce Disability After Ischemic Stroke: The EMAGINE Randomized Clinical Trial. JAMA Netw Open. 2025 Oct 01; 8(10):e2537880. Saver JL, Duncan PW, Stein J, Cramer SC, Fox EJ, Zorowitz RD, Billinger SA, Eickmeyer SM, Kirshblum SC, Androwis GJ, Edwards J, Savitz SI, Koch S, Shall MB, Black-Schaffer RM, Bonato P, Cuccurullo SJ, Barcikowski J, Cao N, Bornstein NM, EMAGINE 1 Trial Investigators. PMID: 41105410; PMCID: PMC12534854.
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Endovascular thrombectomy versus medical management for basilar artery occlusion stroke with mild neurological deficit - results from the BASILAR registry. Neurol Res. 2025 Sep 13; 1-11. Kong Z, Ye L, Wang H, Yang B, Xu J, Qiao K, Fan T, Ding G, Qiu Z, Zhao Z, Xie X, Jiang S, Xu H, Saver JL, Thomalla G, Yang Q, Sang H, Nguyen TN, Qiu Z, Luo J, Li M, Liang Y. PMID: 40946161.
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Pharyngeal electrical stimulation to treat dysphagia in acute stroke: learnings from cases in the PhEED clinical trial. J Rehabil Med. 2025 Sep 05; 57:jrm43538. Harvey RL, Smith R, Bathula R, Everton L, Rup N, Saver J, Martin-Harris B, Dziewas R, Mistry S, Hamdy S, Bath P. PMID: 40908833; PMCID: PMC12427991.
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Hospital Implementation of Endovascular Thrombectomy and Health Equity in Acute Stroke Outcomes. Stroke. 2025 Nov; 56(11):3257-3267. Lusk JB, Liu B, O'Brien EC, Hasan D, Fonarow GC, Sheth KN, Schwamm LH, Xian Y, Albers GW, Saver JL, Li F, Mac Grory B. PMID: 40891327; PMCID: PMC12433677.
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Intra-Arterial Tenecteplase After Successful Reperfusion in Large Vessel Occlusion Stroke: A Randomized Clinical Trial. JAMA Neurol. 2025 Sep 01; 82(9):895-904. Hou X, Huang J, Wang L, He Y, Song J, Guo C, Yang S, Shi X, Chen L, Liu Q, Su J, Zeng L, Jiang M, Chen B, Cheng X, Chen S, Pan H, Shen X, Wu Y, Tang X, Wang J, Han S, Pu T, Wu C, Li F, Qu L, Fu Z, Liu H, Li Y, Mei B, Cheng Y, Hu Z, Zhang H, Lv T, Wu M, Xu R, Ye Q, Kong L, Mi S, Wu J, Wang Y, Tian Z, Sun W, Ma J, Xu X, Wu Y, Wang D, Nogueira RG, Nguyen TN, Saver JL, Zi W, Zhou Z. PMID: 40616333; PMCID: PMC12228979.
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Transcranial ultrasonic stimulation of cerebellar fastigial nucleus: First-in-Human feasibility study. Brain Stimul. 2025 Sep-Oct; 18(5):1663-1666. Bahr-Hosseini M, Spivak NM, Hopkins AR, Cisneros S, Hanuscin C, Saha A, Gilbert J, Schafer S, Schafer ME, Liebeskind DS, Monti MM, Saver JL. PMID: 40886912.
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Should We Stop Endovascular Treatment of M2 Occlusions?: A Critical Look at Recent Evidence. Stroke. 2025 Sep; 56(9):2819-2829. Mehta A, Goldman D, Raz E, Desai S, Mistry E, Nguyen T, Sheth S, Jadhav A, Broderick J, Khatri P, Fifi J, Saver JL, Mocco J. PMID: 40854043.
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Device-Detected Atrial Fibrillation in Patients With and Without Cryptogenic Ischemia: The ANTARCTICA Pooled Analysis. Stroke. 2025 Oct; 56(10):2895-2903. Yaghi S, Sposato LA, Shu L, García-Rodríguez D, Castro Urda V, Kreimer F, Gotzmann M, Greisenegger S, Nahab F, Alshaer QN, Koge J, Ikenouchi H, Kitsiou A, Tsivgoulis G, Triantafyllou S, Skrebelyte-Strøm L, Rønning OM, Tancin Lambert A, Aamodt AH, Bufano G, Renda G, Cuadrado Godia E, Pikija S, Buck BH, Ondraskova E, Healey JS, McIntyre WF, Hill MD, Saver JL, Kasner SE, Kamel H, Elkind MSV, Schwamm LH, Kent DM, Katsanos AH, Fridman S, ANTARTICA Investigators. PMID: 40765508.
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Oxygen Extraction Fraction on Baseline MRI Predicts Infarction Growth in Successfully Reperfused Patients. Stroke. 2025 Oct; 56(10):3024-3033. Asghariahmadabad M, Ismail A, Metanat P, Tavakkol E, Bahr-Hosseini M, Szeder V, Colby GP, Saver JL, Yedavalli VS, Smith WS, Ko N, Kim AS, Halabi C, Savastano LE, Saloner D, Cooke DL, Hetts SW, Amans MR, Narsinh KH, Josephson SA, Hess CP, Liebeskind DS, Nael K. PMID: 40755297.
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A pilot comparison of the retention rates of FAST and BEFAST stroke warning-sign mnemonics. Front Neurol. 2025; 16:1624800. Guo S, Saver JL. PMID: 40740849; PMCID: PMC12307487.
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Collaterals at angiography guide clinical outcomes after endovascular stroke therapy in HERMES. J Neurointerv Surg. 2025 Jul 14; 17(8):811-816. Liebeskind DS, Luff MK, Bracard S, Guillemin F, Jahan R, Jovin TG, Majoie CBLM, Mitchell PJ, van der Lugt A, Menon BK, San Roman L, Campbell B, Muir KW, Hill MD, Dippel DWJ, Saver JL, Demchuk AM, Davalos A, White P, Brown SB, Goyal M, HERMES Collaborators. PMID: 38991735.
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Early Tirofiban Infusion after Intravenous Thrombolysis for Stroke. N Engl J Med. 2025 Sep 25; 393(12):1191-1201. Tao C, Liu T, Cui T, Liu J, Li Z, Ren Y, Zhao X, Xie F, Li J, Wang H, Huang L, Li J, Wen J, Zeng J, Zhu J, Li Z, Li D, Hu X, Huang B, Wang J, Zhang C, Ye B, Hou Y, Gan Y, Sun H, Guan F, Shao Y, Liu Z, Ou Z, Fan S, Wang Y, Zhai H, Ni C, Wang H, Zhang C, Zhao Y, Wang G, Zhu Y, Li R, Sun J, Hu H, Cui J, Wang L, Zhang C, Song J, Jing X, Wang A, Wang J, Xu P, Qureshi AI, Nguyen TN, Nogueira RG, Saver JL, Hu W, ASSET-IT Investigators. PMID: 40616232.
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More than half of patients with wake-up stroke have slept through their stroke onset. J Stroke Cerebrovasc Dis. 2025 Aug; 34(8):108388. Andreasyan L, Saver JL. PMID: 40609843.
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The Large Core Paradox. Stroke. 2025 Sep; 56(9):2786-2797. Ter Schiphorst A, Seners P, Arquizan C, Yedavalli V, Olivot JM, Lansberg MG, Muir KW, Parsons MW, Saver JL, Fisher M, Albers GW, Costalat V, Baron JC. PMID: 40567239.
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Intravenous Glyburide in Medical and Endovascular-Treated Large-Core Stroke: A Subgroup Analysis of the CHARM Randomized Clinical Trial. Ann Neurol. 2025 Sep; 98(3):616-624. Kimberly WT, Saver JL, Campbell BCV, Albers GW, Molyneaux BJ, Hinson HE, Rocha M, Mittal S, Bacchi S, Sharma G, Cordonnier C, Steiner T, Toyoda K, Wintermark M, Nogueira RG, Jacobson S, Simard JM, Sheth KN. PMID: 40476628; PMCID: PMC12814300.
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PFO Device Closure in Patients >60 Years of Age With Ischemic Stroke: Results From U.S. Medicare Beneficiaries. JACC Cardiovasc Interv. 2025 May 26; 18(10):1303-1314. Satpathy R, Rodés-Cabau J, Thaler DE, Kent DM, Turner S, Potluri S, Kolli KK, Borgstrom NP, Prillinger JB, Saver JL. PMID: 40436496.
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Intravenous Tenecteplase before Thrombectomy in Stroke. N Engl J Med. 2025 Jul 10; 393(2):139-150. Qiu Z, Li F, Sang H, Yuan G, Xie D, Zhou K, Li M, Meng Z, Kong Z, Ruan Z, Li C, Yang G, Wu J, Long C, Yang B, Hu H, Li Y, Luo J, Shi Z, Huang X, Jiang S, Yi T, Zeng G, Liu J, Luo X, Liu S, Chang M, Wu Y, Tang Y, Tian Z, Yan Z, Zhao H, Peng Y, Dai H, Zhou P, Li H, Liu W, Song D, Lei B, Xia Z, Tan X, Zhao M, Feng X, Cai L, Li Q, Wu Y, Jiang B, Tian Y, Li L, Jiang L, Long X, You F, Tao J, Zhou J, Wu D, Zheng C, Yin C, Wang D, Lu M, Albers GW, Nogueira RG, Campbell BCV, Nguyen TN, Saver JL, Zi W, Yang Q, BRIDGE-TNK Trial Investigators. PMID: 40396577.
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Endovascular thrombectomy in acute stroke with a large ischemic core: A systematic review and meta-analysis of randomized controlled trials. PLoS Med. 2025 Apr; 22(4):e1004484. Lin CH, Lee M, Ovbiagele B, Liebeskind DS, Sanz-Cuesta B, Saver JL. PMID: 40245084; PMCID: PMC12037071.
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Effectiveness of intravenous thrombolysis in patients with large-vessel occlusion receiving endovascular treatment in Korea. Acute Crit Care. 2025 Apr 11. Kim M, Lee JS, Lee SJ, Park SY, Seo J, Hong JM, Park HK, Cha JK, Saver JL, Lee JS. PMID: 40302566; PMCID: PMC12151730.
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Association Between Collateral Status, Blood Pressure During Thrombectomy, and Clinical Outcomes in Patients With Basilar Artery Occlusion. Neurology. 2025 05 13; 104(9):e213504. Luo C, Nguyen TN, Li R, Tao C, Jing X, Xu P, Wang L, Wang A, Gao F, Cai M, Zhang K, Chen M, Jiang X, Shen N, Abdalkader M, Michel P, Saver JL, Nogueira RG, Liu X, Hu W, ATTENTION Investigators. PMID: 40184589.
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Quantification of patent foramen ovale shunt severity by transesophageal echocardiogram and transcranial doppler in routine clinical practice. J Stroke Cerebrovasc Dis. 2025 Jun; 34(6):108306. Sun PY, Tobis JM, Daneshvar SA, Alfonso RC, Liebeskind DS, Saver JL. PMID: 40187543.
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Endovascular treatment in acute intracranial distal medium vessel occlusion stroke: Study protocol and rationale. Int J Stroke. 2025 Jul; 20(6):763-768. Jing X, Nogueira RG, Nguyen TN, Tao C, Zhu Y, Li R, Sun J, Wang L, Zhang C, Liu T, Song J, Saver JL, Hu W. PMID: 40134089.
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Is there diurnal variation in neuroprotective and thrombolytic therapy effect upon acute cerebral ischemia outcome? J Stroke Cerebrovasc Dis. 2025 May; 34(5):108278. Pariona-Vargas F, Mun KT, Lo EH, Starkman S, Sanossian N, Hosseini MB, Stratton S, Eckstein M, Conwit RA, Liebeskind DS, Sharma LK, Rao NM, Shkirkova K, Avila G, Kim-Tenser MA, Saver JL, FAST-MAG Investigators. PMID: 40054793.
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Short-Term Safety and Effectiveness for Tenecteplase and Alteplase in Acute Ischemic Stroke. JAMA Netw Open. 2025 03 03; 8(3):e250548. Rousseau JF, Weber JM, Alhanti B, Saver JL, Messé SR, Schwamm LH, Fonarow GC, Sheth KN, Smith EE, Mullen MT, Silva GS, Mac Grory B, Xian Y, Warach SJ. PMID: 40072434; PMCID: PMC11904722.
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A Nationwide Prospective Registry of Endovascular Thrombectomy for Extra-Large Ischemic Stroke with Large Vessel Occlusion (XL STROKE): Rationale and Design. Cerebrovasc Dis. 2025; 54(6):894-900. Yuan G, Liu L, Liang Y, Wu J, Nguyen TN, Wei S, Cui T, Li X, Yuan Z, Liu S, Zeng G, Ruan Z, Zheng C, Tan X, Tang S, Hao H, Xia H, Nogueira RG, Thomalla G, Campbell B, Saver JL, Yang Q, Long C, Qiu Z, Sang H. PMID: 39999799.
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Modified Rankin Scale at 90 Days Versus National Institutes of Health Stroke Scale at 24 Hours as Primary Outcome in Acute Stroke Trials. J Am Heart Assoc. 2025 Mar 04; 14(5):e037752. Ospel JM, Brown S, Bosshart S, Stebner A, Uchida K, Demchuk A, Saver JL, White P, Muir KW, Dippel DWJ, Majoie CBLM, Jovin TG, Campbell BCV, Mitchell PJ, Bracard S, Guillemin F, Hill M, Goyal M, HERMES Investigators. PMID: 39968801; PMCID: PMC12132765.
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Trends in Ischemic Stroke Hospitalization and Outcomes in the United States Pre- and Peri-COVID-19 Pandemic: A National Inpatient Sample Study. J Clin Med. 2025 Feb 18; 14(4). Jafarli A, Di Napoli M, Kasper RS, Saver JL, McCullough LD, Salehi-Omran S, Mansouri B, Lioutas VA, Ismail M, Divani AA. PMID: 40004882; PMCID: PMC11856848.
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Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke: The POST-UK Randomized Clinical Trial. JAMA. 2025 02 18; 333(7):589-598. Liu C, Guo C, Li F, Yu N, Huang J, Peng Z, Kong W, Song J, Liu X, Fan S, Yue C, Chen B, Zheng C, Yuan X, Sheng J, Wu Y, Sun B, Zhao Z, Zhu M, Han L, Shi Q, Xia Z, Shang X, Li F, Li R, Yue F, Jiang S, Song D, Song M, Shan Y, Ding C, Yao L, Yang Y, Chen J, He W, Pan F, Zhang W, Cai T, Han S, Li W, Li G, Gong C, Huang L, Huang C, Wang D, Kaesmacher J, Nguyen TN, Nogueira RG, Saver JL, Zi W, Chen Y, Yang Q, POST-UK investigators. PMID: 39804674; PMCID: PMC11836763.
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Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke: The POST-TNK Randomized Clinical Trial. JAMA. 2025 02 18; 333(7):579-588. Huang J, Yang J, Liu C, Li L, Yang D, Guo C, Zeng G, Song J, Ma J, Xu X, Shi X, Yang S, Sun W, Wang Z, Tang Y, Jiang M, Wang L, Cheng X, Luo J, Zhou P, Fang X, Cheng G, Ruan Z, Li J, Liu J, Lei B, Tian Y, Tan X, Yuan G, Wang J, Huang X, Deng S, Jin Z, Zou X, Zhang J, Cheng D, Luo X, Liao J, Miao J, Li Z, Sun Y, Jiang G, Kong D, Jiang S, Wang Z, Wang D, Kaesmacher J, Nguyen TN, Nogueira RG, Saver JL, Chen Y, Zi W, POST-TNK Investigators. PMID: 39804681; PMCID: PMC11836761.
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Endovascular Treatment for Stroke Due to Occlusion of Medium or Distal Vessels. N Engl J Med. 2025 Apr 10; 392(14):1374-1384. Psychogios M, Brehm A, Ribo M, Rizzo F, Strbian D, Räty S, Arenillas JF, Martínez-Galdámez M, Hajdu SD, Michel P, Gralla J, Piechowiak EI, Kaiser DPO, Puetz V, Van den Bergh F, De Raedt S, Bellante F, Dusart A, Hellstern V, Khanafer A, Parrilla G, Morales A, Kirschke JS, Wunderlich S, Fiehler J, Thomalla G, Lemmens R, Peluso JP, Bolognese M, von Hessling A, van Es A, Kruyt ND, Coutinho JM, Castaño C, Minnerup J, van Zwam W, Dhondt E, Nolte CH, Machi P, Loehr C, Mattle HP, Buhk JH, Kaesmacher J, Dobrocky T, Papanagiotou P, Alonso A, Holtmannspoetter M, Zini A, Renieri L, Keil F, van den Wijngaard I, Kägi G, Terceño M, Wiesmann M, Amaro S, Rommers N, Balmer L, Fragata I, Katan M, Leker RR, Saver JL, Staals J, Fischer U, DISTAL Investigators. PMID: 39908430.
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A new taxonomy of neuroprotective agents for stroke appropriate for the reperfusion era. Front Neurol. 2024; 15:1514924. Bahr-Hosseini M, Saver JL. PMID: 40040642; PMCID: PMC11878098.
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Comparative Effectiveness of Rosuvastatin Versus Atorvastatin in Acute Ischemic Stroke Treatment. J Am Heart Assoc. 2025 Feb 04; 14(3):e038080. Kim JT, Lee JS, Kim H, Kim BJ, Kang J, Lee KJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Park TH, Lee K, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Choi JC, Kwon JH, Kim WJ, Shin DI, Yum KS, Sohn SI, Hong JH, Lee SH, Park MS, Ryu WS, Park KY, Lee J, Saver JL, Bae HJ. PMID: 39895542; PMCID: PMC12074770.
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Impact of Onset-to-Door Time on Endovascular Therapy for Basilar Artery Occlusion. J Stroke. 2025 Jan; 27(1):140-143. Liu T, Tao C, Chen Z, Xu L, Zhu Y, Li R, Sun J, Wang L, Zhang C, Song J, Jing X, Qureshi AI, Abdalkader M, Nguyen TN, Nogueira RG, Saver JL, Hu W. PMID: 39916466; PMCID: PMC11834346.
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A Systematic Literature Review on the Burden of Disease for Patients With Moderate to Severe Acute Ischemic Stroke. Medicine (Baltimore). 2025 Jan 17; 104(3):e41249. Quinn T, Kitagawa K, Leung T, Molina C, Rabinstein A, Bentley R, Henry O, Heuser M, Nair V, Saver J. PMID: 39836564; PMCID: PMC11749521.
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DWI Positivity in Mild, Nondisabling Acute Cerebral Ischemia: Data From the PRISMS Trial. Stroke Vasc Interv Neurol. 2025 Mar; 5(2):e001613. Wang LL, Khatri P, Prabhakaran S, Sucharew H, Tomsick TA, Carrozzella JA, Stanton RJ, Broderick J, Kleindorfer D, Levine SR, Romano JG, Saver JL, Yeatts SD, Vagal A. PMID: 41573186; PMCID: PMC12671632.
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Intra-arterial tenecteplase after successful endovascular recanalisation in patients with acute posterior circulation arterial occlusion (ATTENTION-IA): multicentre randomised controlled trial. BMJ. 2025 Jan 14; 388:e080489. Hu W, Tao C, Wang L, Chen Z, Li D, Chen W, Yi T, Xu L, Yu C, Wang T, Yao X, Cui T, Yuan G, Su J, Chen L, Zhou Z, Ma Z, Wang J, Wang B, Han H, Wang H, Chen J, Zhou P, Cao Z, Ren Y, Cai X, Shi H, Zhang G, Yu L, Yuan X, Li J, Zeng G, Ni C, Li T, Wu Y, Li Y, Li K, Liu Y, Wang Y, Jin Y, Liu H, Wen J, Sun J, Zhu Y, Li R, Zhang C, Liu T, Song J, Wang L, Cheng J, Qureshi AI, Nguyen TN, Saver JL, Nogueira RG, Liu X. PMID: 39809509; PMCID: PMC11729139.
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Understanding Noninferiority Trials: What Stroke Specialists Should Know. Stroke. 2025 Feb; 56(2):543-552. Cavalcante F, Treurniet KM, Kappelhof M, Kaesmacher J, Lingsma HF, Saver JL, Gralla J, Fischer U, Majoie CB, Roos YBWEM. PMID: 39744847.
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Influence of prestroke glycemic status on outcomes by age in patients with acute ischemic stroke and diabetes mellitus. Eur J Neurol. 2025 Jan; 32(1):e70004. Kim JT, Lee JS, Kim H, Kim BJ, Kang J, Lee KJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Park TH, Lee K, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Choi JC, Kwon JH, Kim WJ, Shin DI, Yum KS, Sohn SI, Hong JH, Lee SH, Kim C, Park MS, Ryu WS, Park KY, Lee J, Saver JL, Bae HJ. PMID: 39714194; PMCID: PMC11664728.
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Intra-arterial tenecteplase following endovascular therapy in patients with acute posterior circulation arterial occlusion: study protocol and rationale. J Neurointerv Surg. 2024 Dec 26; 17(e1):e68-e73. Tao C, Li R, Sun J, Zhu Y, Wang L, Zhang C, Liu T, Song J, Qureshi AI, Abdalkader M, Nguyen TN, Saver JL, Nogueira RG, Hu W. PMID: 38124230.
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Magnitude of effect of low dose colchicine, a newly food and drug administration approved treatment for stroke prevention. J Stroke Cerebrovasc Dis. 2025 Feb; 34(2):108186. Escalera E, Saver JL. PMID: 39667442.
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Association Between Time to Treatment and Outcomes of Endovascular Therapy vs Medical Management in Patients With Large Ischemic Stroke. Neurology. 2025 Jan 14; 104(1):e210133. Yuan G, Sang H, Nguyen TN, Huo X, Pan Y, Wang M, Qiu Z, Liu L, Xia H, Wu J, Long C, Xu J, Huang F, He B, Wu D, Wang H, Feng C, Liang Y, Zhou X, Yang W, Huang Z, Xiang Y, Lei L, Saver JL, Miao Z, Cai X. PMID: 39652807.
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A Prospective Multicenter Analysis of Mobile Stroke Unit Cost-Effectiveness. Ann Neurol. 2025 Feb; 97(2):209-221. Rajan SS, Yamal JM, Wang M, Saver JL, Jacob AP, Gonzales NR, Ifejika N, Parker SA, Ganey C, Gonzalez MO, Lairson DR, Bratina PL, Jones WJ, Mackey JS, Lerario MP, Navi BB, Alexandrov AW, Alexandrov A, Nour M, Spokoyny I, Bowry R, Czap AL, Grotta JC. PMID: 39625067.
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Intravenous glibenclamide for cerebral oedema after large hemispheric stroke (CHARM): a phase 3, double-blind, placebo-controlled, randomised trial. Lancet Neurol. 2024 12; 23(12):1205-1213. Sheth KN, Albers GW, Saver JL, Campbell BCV, Molyneaux BJ, Hinson HE, Cordonnier C, Steiner T, Toyoda K, Wintermark M, Littauer R, Collins J, Lucas N, Nogueira RG, Simard JM, Wald M, Dawson K, Kimberly WT, CHARM Trial investigators. PMID: 39577921.
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Mobile Stroke Unit Management in Patients With Acute Ischemic Stroke Eligible for Intravenous Thrombolysis. JAMA Neurol. 2024 12 01; 81(12):1250-1262. Mac Grory B, Sun JL, Alhanti B, Lusk J, Li F, Adeoye O, Furie K, Hasan D, Messe S, Sheth KN, Schwamm LH, Smith EE, Bhatt DL, Fonarow GC, Saver JL, Xian Y, Grotta J. PMID: 39466286; PMCID: PMC11581552.
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Automated assessment of ischemic core on non-contrast computed tomography: a multicenter comparative analysis with CT perfusion. J Neurointerv Surg. 2024 Nov 22; 16(12):1288-1293. Shahrouki P, Kihira S, Tavakkol E, Qiao JX, Vagal A, Khatri P, Bahr-Hosseini M, Colby GP, Jahan R, Duckwiler G, Szeder V, Ledbetter L, Cai S, Salehi B, Doshi AH, Belani P, Fifi JT, De Leacy R, Mocco J, Saver JL, Liebeskind DS, Nael K. PMID: 37918907.
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Advancing stroke safety and efficacy through early tirofiban administration after intravenous thrombolysis: The multicenter, randomized, placebo-controlled, double-blind ASSET IT trial protocol. Int J Stroke. 2025 Mar; 20(3):373-377. Tao C, Liu T, Sun J, Zhu Y, Li R, Wang L, Zhang C, Song J, Jing X, Nguyen TN, Nogueira RG, Saver JL, Hu W. PMID: 39501470.
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Care Quality and Outcomes of Ischemic Stroke in Patients With Premorbid Dementia: Get With The Guidelines-Stroke Registry. Stroke. 2024 12; 55(12):2901-2905. Ganesh A, Wang M, Schwamm LH, Fonarow GC, Messé SR, Xian Y, Saver JL, Smith EE. PMID: 39503052.
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Mobile stroke units services in Germany: A cost-effectiveness modeling perspective on catchment zones, operating modes, and staffing. Eur J Neurol. 2025 Jan; 32(1):e16514. Rink JS, Szabo K, Hoyer C, Saver JL, Nour M, Audebert HJ, Kunz WG, Froelich MF, Heinzl A, Tschalzev A, Hoffmann J, Schoenberg SO, Tollens F. PMID: 39506352; PMCID: PMC11622509.
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Effect of Intravenous Tirofiban Versus Placebo on First-Pass Successful Reperfusion in Endovascular Stroke Thrombectomy: Insights From the RESCUE BT Randomized Clinical Trial. J Am Heart Assoc. 2024 Nov 05; 13(21):e036350. Yuan J, Ge H, Tao Z, An H, Han Q, Saver JL, Nguyen TN, Zhou S, Mao A, Wu Y, Nogueira RG, Sun Y, Jiang S, Wei L, Fu X, Bai Y, Yang S, Hu W, Zhang G, Pan C, Zhang S, Qiao L, Chen Q, Sang H, Qiu Z, Wu F, Chang M, Ruan Z. PMID: 39494598; PMCID: PMC11935663.
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POST-UK (Adjunctive Intra-Arterial Urokinase After Successful Endovascular Thrombectomy in Patients With Large-Vessel Occlusion Stroke): Study Protocol of a Multicenter, Prospective, Randomized, Open-Label, Blinded-End Point Trial. Stroke Vasc Interv Neurol. 2025 Mar; 5(2):e001563. Liu C, Li F, Song J, Xu X, Huang J, Guo C, Kong W, Yang J, Shi X, Ma J, Yang S, Wang Z, Fan S, Xiang L, Wenzhe S, Yu N, Yue C, Peng Z, Li L, Huang C, Yang D, Wang D, Saver J, Nguyen TN, Nogueira RG, Chen Y, Zi W. PMID: 41573192; PMCID: PMC12671629.
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Mechanical Thrombectomy Access Score: A Systematic Review and Modified Delphi of Global Barriers to Endovascular Therapy. Stroke. 2025 01; 56(1):158-167. Aroor SR, Zevallos CB, Asif KS, Singh N, Potter-Vig J, Rodriguez-Calienes A, Menon BK, Ganesh A, Saver JL, Kamel H, Alexandrov AW, Jauch EC, Miao Z, Huo X, Ramakrishnan P, Desai SM, Limaye K, El-Ghanem M, Toth G, Rao CV, Masoud HE, Wang QT, Herial NA, Atchaneeyasakul K, Szeder V, Amuluru K, Urrutia VC, Al-Mufti F, Yavagal DR, Ortega-Gutierrez S. PMID: 39450508.
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Efficacy and Safety of Intravenous Tenecteplase Before Endovascular Thrombectomy for Acute Ischemic Stroke: The Multicenter, Randomized, BRIDGE-TNK Trial Protocol. J Am Heart Assoc. 2024 Nov 05; 13(21):e036765. Qiu Z, Li F, Xie D, Yuan G, Nguyen TN, Zhou K, Nogueira RG, Saver JL, Campbell BCV, Albers GW, Sang H, Li L, Tian Y, Meng Z, Wang D, Zi W, Yang Q, BRIDGE-TNK investigators. PMID: 39435713; PMCID: PMC11935713.
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Twenty Years of Sustained Improvement in Quality of Care and Outcomes for Patients Hospitalized With Stroke or Transient Ischemic Attack: Data From The Get With The Guidelines-Stroke Program. Stroke. 2024 11; 55(11):2599-2610. Xian Y, Li S, Jiang T, Beon CD, Poudel R, Thomas K, Reeves MJ, Smith EE, Saver JL, Sheth KN, Messé SR, Schwamm LH, Fonarow GC. PMID: 39429153; PMCID: PMC11518659.
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Tigertriever in the treatment of acute ischemic stroke with underlying intracranial atherosclerotic disease. J Neurointerv Surg. 2024 Oct 14; 16(11):1083-1087. Ojeda DJ, Ghannam M, Sanchez S, Almajali M, Koul P, Saver JL, Gupta R, Ortega-Gutierrez S, Liebeskind DS, Samaniego EA. PMID: 37777257; PMCID: PMC11503153.
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Pre-hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT-2 trial. Eur J Neurol. 2024 Dec; 31(12):e16502. Appleton JP, Dixon M, Woodhouse LJ, Anderson CS, Ankolekar S, Cala L, England TJ, Godolphin PJ, Krishnan K, Mair G, Muir KW, Potter J, Price CI, Randall M, Robinson TG, Roffe C, Rothwell PM, Sandset EC, Saver JL, Siriwardena AN, Wardlaw JM, Sprigg N, Bath PM, RIGHT-2 Investigators. PMID: 39392040; PMCID: PMC11554870.
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Anticoagulation vs Antiplatelets Across Subgroups of Embolic Stroke of Undetermined Source: A Meta-Analysis of Randomized Controlled Trials. Neurology. 2024 Nov 12; 103(9):e209949. Ghannam M, Al-Qudah AM, Alshaer QN, Kronmal R, Ntaios G, Childs CA, Longstreth WT, Alsawareah A, Keller T, Serna-Higuita LM, Geisler T, Furie K, Saver JL, Kasner SE, Elkind MSV, Tirschwell D, Poli S, Kamel H, Yaghi S. PMID: 39365971; PMCID: PMC12747887.
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Impact of non-traditional lipid profiles on 1-year vascular outcomes in ischemic stroke patients with prior statin therapy and LDL-C < 100 mg/dL. Sci Rep. 2024 10 01; 14(1):22794. Kim H, Kim JT, Lee JS, Kim BJ, Kang J, Lee KJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Park TH, Lee K, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Choi JC, Kwon JH, Kim WJ, Shin DI, Yum KS, Sohn SI, Hong JH, Lee SH, Park MS, Ryu WS, Park KY, Lee J, Saver JL, Bae HJ. PMID: 39354143; PMCID: PMC11448496.
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Endovascular vs Medical Management of Acute Basilar Artery Occlusion: A Secondary Analysis of a Randomized Clinical Trial. JAMA Neurol. 2024 Oct 01; 81(10):1043-1050. Li R, Tao C, Sun J, Zhang C, Xu P, Yin Y, Han H, Yuan G, Cui T, Zhou P, Chen W, Zeng G, Li Y, Ma Z, Yu C, Su J, Zhou Z, Chen Z, Wang L, Luo C, Jing X, Wang A, Shen N, Abdalkader M, Nguyen TN, Qureshi AI, Saver JL, Nogueira RG, Hu W, ATTENTION Investigators. PMID: 39186280; PMCID: PMC11348088.
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Adjunctive intra-arterial tenecteplase after successful endovascular thrombectomy in patients with large vessel occlusion stroke (POST-TNK): Study rationale and design. Eur Stroke J. 2025 Jun; 10(2):618-623. Huang J, Guo C, Yang J, Shi X, Liu C, Song J, Li F, Kong W, Fan S, Peng Z, Yang S, Ma J, Xu X, Li L, Wang Z, Yu N, Sun W, Yue C, Liu X, Yang D, Huang C, Wang D, Nogueira RG, Nguyen TN, Saver JL, Chen Y, Zi W. PMID: 39345180; PMCID: PMC11556599.
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Adaptive Trials in Stroke: Current Use and Future Directions. Neurology. 2024 Oct 22; 103(8):e209876. Hayward KS, Dalton EJ, Campbell BCV, Khatri P, Dukelow SP, Johns H, Walter S, Yogendrakumar V, Pandian JD, Sacco S, Bernhardt J, Parsons MW, Saver JL, Churilov L. PMID: 39325999; PMCID: PMC11436319.
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Guideline Updates Needed: Closure Devices to Prevent Recurrent Stroke in Patients With Patent Foramen Ovale. J Am Heart Assoc. 2024 Sep 03; 13(17):e035937. Saver JL. PMID: 39190590; PMCID: PMC11646535.
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Endovascular therapy in acute ischemic stroke with poor reperfusion is associated with worse outcomes compared with best medical management: a HERMES substudy. J Neurointerv Surg. 2024 Aug 14; 16(9):878-883. Rex N, Ospel JM, Brown SB, McDonough RV, Kashani N, Hill MD, Dippel DWJ, Campbell B, Muir KW, Demchuk AM, Bracard S, Guillemin F, Jovin TG, Mitchell PJ, White P, Majoie CBLM, Saver JL, Goyal M. PMID: 37532454.
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Heed the Warning Signs to Avoid Serious ARIA. Neurology. 2024 Sep 10; 103(5):e209674. Salloway SP, Schrag M, Saver JL. PMID: 39121446.
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Intracranial artery calcification: Frequency, determinants, and modification of outcomes from endovascular thrombectomy. J Stroke Cerebrovasc Dis. 2024 Nov; 33(11):107898. Phan AQ, Yoo B, Liebeskind DS, Sharma LK, Bahr-Hosseini M, Alfonso R, Jahan R, Duckwiler GR, Tateshima S, Nour M, Szeder V, Colby GP, Gornbein J, Saver JL, for UCLA Endovascular Thrombectomy Investigators. PMID: 39106922.
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Modified Rankin Scale disability status at day 4 poststroke is an informative predictor of long-term day 90 outcome. J Stroke Cerebrovasc Dis. 2024 Nov; 33(11):107902. Taleb S, Ji-Hyun Lee J, Asanad S, Starkman S, Hamilton S, Gornbein J, Conwit RA, Sanossian N, Saver JL. PMID: 39084338.
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HERMES-24 Score Derivation and Validation for Simple and Robust Outcome Prediction After Large Vessel Occlusion Treatment. Stroke. 2024 08; 55(8):1982-1990. Tanaka K, Brown S, Goyal M, Menon BK, Campbell BCV, Mitchell PJ, Jovin TG, Saver JL, Muir KW, White PM, Bracard S, Guillemin F, Roos YBWEM, van Zwam WH, Najm M, Dowlatshahi D, Hill MD, Demchuk AM, HERMES Collaborators. PMID: 39038101.
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Prevalence and Angiographic Outcomes of Rescue Intracranial Stenting in Large Vessel Occlusion Following Stroke Thrombectomy - STRATIS. Stroke Vasc Interv Neurol. 2025 Mar; 5(2):e001378. Saber H, Froehler MT, Zaidat OO, Aziz-Sultan A, Klucznik RP, Saver JL, Sanossian N, Hellinger FR, Yavagal DR, Yao TL, Jahan R, Haussen DC, Nogueira RG, Mueller-Kronast NH, Liebeskind DS, STRATIS Investigators. PMID: 41573184; PMCID: PMC12671625.
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AC-ASPECTS, ACh-ASPECTS, and H-ASPECTS: new imaging scales to assess territorial and total cerebral hemispheric ischemic injury. Front Neurol. 2024; 15:1397120. Rodriguez MP, Taleb S, Lee JJ, Liebeskind DS, Saver JL. PMID: 39022729; PMCID: PMC11252022.
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The National Institutes of Health Stroke Scale is comparable to the ICH score in predicting outcomes in spontaneous acute intracerebral hemorrhage. Front Neurol. 2024; 15:1401793. Kazaryan SA, Shkirkova K, Saver JL, Liebeskind DS, Starkman S, Bulic S, Poblete R, Kim-Tenser M, Guo S, Conwit R, Villablanca P, Hamilton S, Sanossian N. PMID: 39011360; PMCID: PMC11246900.
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Golden Hour Intravenous Thrombolysis for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. Ann Neurol. 2024 Sep; 96(3):582-590. Al-Ajlan FS, Alkhiri A, Alamri AF, Alghamdi BA, Almaghrabi AA, Alharbi AR, Alansari N, Almilibari AZ, Hussain MS, Audebert HJ, Grotta JC, Shuaib A, Saver JL, Alhazzani A. PMID: 38922985.
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Mode of Onset Modifies the Effect of Time to Endovascular Reperfusion on Clinical Outcomes after Acute Ischemic Stroke: An Analysis of the DAWN Trial. Ann Neurol. 2024 Aug; 96(2):356-364. Nogueira RG, Doheim MF, Jadhav AP, Aghaebrahim A, Frankel MR, Jankowitz BT, Budzik RF, Bonafe A, Bhuva P, Yavagal DR, Hanel RA, Hassan AE, Ribo M, Cognard C, Sila CA, Jenkins P, Smith WS, Saver JL, Liebeskind DS, Jovin TG, Haussen DC. PMID: 38877793.
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Statin Overuse in Cerebral Ischemia Without Indications: Systematic Review and Annual US Burden of Adverse Events. Stroke. 2024 08; 55(8):2022-2033. Sung EM, Saver JL. PMID: 38873773.
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Intravenous tenecteplase for acute ischemic stroke between 4.5 and 6 h of onset (EXIT-BT2): Rationale and Design. Eur Stroke J. 2025 Jun; 10(2):624-630. Wang YH, Guo ZN, Chen MR, Yao ZG, Nguyen TN, Saver JL, Yang Y, Chen HS. PMID: 38859581; PMCID: PMC11569533.
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Exploring the Limits of Endovascular Therapy for Large Core Patients: Where Do We Need More Data? Stroke. 2024 07; 55(7):1956-1960. Albers GW, Heit JJ, Lansberg MG, Inoue M, Huo X, Yedavalli VS, Seners P, McCullough-Hicks M, Cereda CW, Tsai JP, Mistry EA, Chatterjee AR, Derdeyn CP, Khatri P, Olivot JM, Hill MD, Saver JL, Fisher M. PMID: 38836345; PMCID: PMC11551168.
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Statistical Analysis Plan for the INTEnsive Ambulance-Delivered Blood Pressure Reduction in Hyper-ACute Stroke Trial. Cerebrovasc Dis. 2025; 54(2):278-281. Billot L, Chen C, Song L, Lin Y, Liu F, Chen X, Arima H, Bath PM, Ford GA, Robinson TG, Sandset EC, Saver JL, Sprigg N, van der Worp HB, Yang J, Li G, Anderson CS, INTERACT4 Investigators. PMID: 38815572.
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Mapping the Ecological Terrain of Stroke Prehospital Delay: A Nationwide Registry Study. Stroke. 2024 06; 55(6):1507-1516. Dhand A, Reeves MJ, Mu Y, Rosner BA, Rothfeld-Wehrwein ZR, Nieves A, Dhongade VA, Jarman M, Bergmark RW, Semco RS, Ader J, Marshall BDL, Goedel WC, Fonarow GC, Smith EE, Saver JL, Schwamm LH, Sheth KN. PMID: 38787926; PMCID: PMC11299104.
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Trends in Dual Antiplatelet Therapy of Aspirin and Clopidogrel and Outcomes in Ischemic Stroke Patients Noneligible for POINT/CHANCE Trial Treatment. J Am Heart Assoc. 2024 May 21; 13(10):e033611. Kim JT, Lee JS, Kim H, Kim BJ, Lee KJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Park TH, Lee K, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Choi JC, Kwon JH, Kim WJ, Shin DI, Yum KS, Sohn SI, Hong JH, Lee SH, Park MS, Ryu WS, Park KY, Lee J, Saver JL, Bae HJ. PMID: 38761083; PMCID: PMC11179811.
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Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke. N Engl J Med. 2024 05 30; 390(20):1862-1872. Li G, Lin Y, Yang J, Anderson CS, Chen C, Liu F, Billot L, Li Q, Chen X, Liu X, Ren X, Zhang C, Xu P, Wu L, Wang F, Qiu D, Jiang M, Peng Y, Li C, Huang Y, Zhao X, Liang J, Wang Y, Wu X, Xu X, Chen G, Huang D, Zhang Y, Zuo L, Ma G, Yang Y, Hao J, Xu X, Xiong X, Tang Y, Guo Y, Yu J, Li S, He S, Mao F, Tan Q, Tan S, Yu N, Xu R, Sun M, Li B, Guo J, Liu L, Liu H, Ouyang M, Si L, Arima H, Bath PM, Ford GA, Robinson T, Sandset EC, Saver JL, Sprigg N, van der Worp HB, Song L, INTERACT4 investigators, INTERACT4 Investigators. PMID: 38752650.
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Automated Assessment of the DWI-FLAIR Mismatch in Patients with Acute Ischemic Stroke: Added Value to Routine Clinical Practice. AJNR Am J Neuroradiol. 2024 05 09; 45(5):562-567. Tavakkol E, Kihira S, McArthur M, Polson J, Zhang H, Arnold CW, Yoo B, Linetsky M, Salehi B, Ledbetter L, Kim C, Jahan R, Duckwiler G, Saver JL, Liebeskind DS, Nael K. PMID: 38290738; PMCID: PMC11288547.
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Patent Foramen Ovale Closure in Older Patients With Stroke: Patient Selection for Trial Feasibility. Neurology. 2024 May 28; 102(10):e209388. Wang AY, Rothwell PM, Nelson J, Saver JL, Kasner SE, Carroll J, Mas JL, Derumeaux G, Chatellier G, Furlan AJ, Herrmann HC, Jüni P, Kim JS, Koethe B, Lee PH, Lefebvre B, Mattle HP, Meier B, Reisman M, Smalling RW, Sondergaard L, Song JK, Di Angelantonio E, DiTullio M, Elkind MSV, Homma S, Jaigobin C, Michel P, Mono ML, Nedeltchev K, Papetti F, Serena J, Weimar C, Li L, Mazzucco S, Silver LE, van Klaveren D, Thaler DE, Kent DM. PMID: 38701403.
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Cross-Sectional Imaging Modalities in Correlation to the Thrombolysis in Cerebral Infarction Score: The Next Frontier in Adjunctive Endovascular Stroke Therapy. Stroke Vasc Interv Neurol. 2025 Jan; 5(1):e001063. Kaesmacher J, Treurniet KM, Kappelhof M, Dobrocky T, Ospel J, Mujanovic A, Fiehler J, Yan B, Goyal M, Yoo AJ, Campbell B, Zaidat OO, Saver JL, Sanossian N, Raychev R, Roos YBWEM, Fischer U, Majoie CBLM, Gralla J, Liebeskind DS. PMID: 41608398; PMCID: PMC11864582.
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MRI in the Evaluation of Cryptogenic Stroke and Embolic Stroke of Undetermined Source. Radiology. 2024 04; 311(1):e231934. Xiao J, Poblete RA, Lerner A, Nguyen PL, Song JW, Sanossian N, Wilcox AG, Song SS, Lyden PD, Saver JL, Wasserman BA, Fan Z. PMID: 38652031; PMCID: PMC11070612.
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TOAST stroke subtype classification in clinical practice: implications for the Get With The Guidelines-Stroke nationwide registry. Front Neurol. 2024; 15:1375547. Rathburn CM, Mun KT, Sharma LK, Saver JL. PMID: 38585349; PMCID: PMC10995393.
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Edoxaban for the treatment of hypercoagulability and cerebral thromboembolism associated with cancer: A randomized clinical trial of biomarker targets. Int J Stroke. 2024 Jul; 19(6):645-653. Chung JW, Hwang J, Kim HJ, Seo WK, Ahn MJ, Saver JL, Bang OY. PMID: 38429253.
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Arterial Tortuosity Is a Potent Determinant of Safety in Endovascular Therapy for Acute Ischemic Stroke. Stroke Vasc Interv Neurol. 2024 May; 4(3):e001178. Saber H, Colby GP, Mueller-Kronast N, Aziz-Sultan MA, Klucznik R, Saver JL, Sanossian N, Hellinger FR, Yavagal DR, Yao TL, Jahan R, Haussen DC, Nogueira RG, Froehler MT, Zaidat OO, Liebeskind DS, STRATIS Investigators. PMID: 41584471; PMCID: PMC12778508.
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Patent Foramen Ovale-Associated Stroke: A Neurologist's Perspective. Cardiol Clin. 2024 Nov; 42(4):487-495. Saver JL. PMID: 39322339.
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Stroke in the Time of Circadian Medicine. Circ Res. 2024 03 15; 134(6):770-790. Mergenthaler P, Balami JS, Neuhaus AA, Mottahedin A, Albers GW, Rothwell PM, Saver JL, Young ME, Buchan AM. PMID: 38484031.
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Methylprednisolone as Adjunct to Endovascular Thrombectomy for Large-Vessel Occlusion Stroke: The MARVEL Randomized Clinical Trial. JAMA. 2024 03 12; 331(10):840-849. MARVEL Trial Authors for the MARVEL Investigators, Yang Q, Guo C, Yue C, Song J, Yang J, Peng Z, Yu N, Huang J, Li L, Huang J, Chen Y, Zheng C, Jiang S, Ruan Z, Zhang M, Song D, Luo X, Tian Y, Yang M, Deng S, Wei S, Wu Y, Tang Y, Tan X, Zeng G, Cheng D, Liu W, He W, Cai T, Pan C, Liao J, Lei B, Pu S, Jin Z, Li J, Xia Z, Zhang G, Luo J, Sun Y, Xiong X, Wang J, Li B, Peng Y, Chen K, Shan Y, Zhou P, Huang X, Luo S, Zhang J, Liu C, Jiang L, Yang D, Tian Y, Hu J, Qiu Z, Ma J, Xu X, Fan S, Liu X, Xie D, Niu J, Zheng H, Ouyang Q, Wang D, Nguyen TN, Saver JL, Nogueira RG, Li F, Zi W. PMID: 38329440; PMCID: PMC10853866.
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Remote Ischemic Conditioning With Medical Management or Reperfusion Therapy for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. Neurology. 2024 Apr 09; 102(7):e207983. Li Q, Guo J, Chen HS, Blauenfeldt RA, Hess DC, Pico F, Khatri P, Campbell BCV, Feng X, Abdalkader M, Saver JL, Nogueira RG, Jiang B, Li B, Yang M, Sang H, Yang Q, Qiu Z, Dai Y, Nguyen TN. PMID: 38457772; PMCID: PMC11033986.
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What Is a Meaningful Difference When Using Infarct Volume as the Primary Outcome?: Results From the HERMES Database. Stroke. 2024 04; 55(4):866-873. Rinkel LA, Ospel JM, Brown SB, Campbell BCV, Dippel DWJ, Demchuk AM, Majoie CBLM, Mitchell PJ, Bracard S, Guillemin F, Jovin TG, Muir KW, White P, Saver JL, Hill MD, Goyal M, HERMES Collaborators. PMID: 38440891.
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Brain imaging prior to thrombectomy in the late window of large vessel occlusion ischemic stroke: a systematic review and meta-analysis. Neuroradiology. 2024 May; 66(5):809-816. Lin CH, Ovbiagele B, Liebeskind DS, Saver JL, Lee M. PMID: 38427071.
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Influence of Time to Achieve Target Systolic Blood Pressure on Outcome After Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration. Stroke. 2024 04; 55(4):849-855. Wang X, Yang J, Moullaali TJ, Sandset EC, Woodhouse LJ, Law ZK, Arima H, Butcher KS, Delcourt C, Edwards L, Gupta S, Jiang W, Koch S, Potter J, Qureshi AI, Robinson TG, Al-Shahi Salman R, Saver JL, Sprigg N, Wardlaw J, Anderson CS, Sakamoto Y, Bath PM, Chalmers J, Blood Pressure in Acute Stroke (BASC) Investigators. PMID: 38410986.
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Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial. Stroke Vasc Neurol. 2024 02 27; 9(1):38-49. Appleton JP, Woodhouse LJ, Anderson CS, Ankolekar S, Cala L, Dixon M, England TJ, Krishnan K, Mair G, Muir KW, Potter J, Price CI, Randall M, Robinson TG, Roffe C, Sandset EC, Saver JL, Shone A, Siriwardena AN, Wardlaw JM, Sprigg N, Bath PM, RIGHT-2 Investigators. PMID: 37290930; PMCID: PMC10956104.
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Adjunct Intraarterial or Intravenous Tirofiban Versus No Tirofiban After Successful Recanalization of Basilar Artery Occlusion Stroke: The BASILAR Registry. J Am Heart Assoc. 2024 Mar 05; 13(5):e032326. Li H, Ju D, Tao Z, Wang J, Nguyen TN, Saver JL, Nogueira RG, Liu C, Yang Q, Qiu Z, Yin C, Sun D, Liu S. PMID: 38390817; PMCID: PMC10944024.
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Intravenous Tirofiban Versus Alteplase Before Endovascular Treatment in Acute Ischemic Stroke: A Pooled Analysis of the DEVT and RESCUE BT Trials. Stroke. 2024 04; 55(4):856-865. Sang H, Cao Z, Du J, Nguyen TN, Saver JL, Mao A, Nogueira RG, Tao Z, Zhou S, Han Q, Sun D, Lei B, Liu S, Zeng G, Yin C, Xie D, Luo W, Jin Z, Qiu Z, DEVT and RESCUE BT Trial Investigators. PMID: 38362756.
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Time to Anticoagulation Reversal and Outcomes After Intracerebral Hemorrhage. JAMA Neurol. 2024 Feb 09. Sheth KN, Solomon N, Alhanti B, Messe SR, Xian Y, Bhatt DL, Hemphill JC, Frontera JA, Chang RC, Danelich IM, Huang J, Schwamm L, Smith EE, Goldstein JN, Mac Grory B, Fonarow GC, Saver JL. PMID: 38335064; PMCID: PMC11002694.
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Variation in Vessel Size and Angiographic Outcomes Following Stent-Retriever Thrombectomy in Acute Ischemic Stroke: STRATIS Registry. Stroke Vasc Interv Neurol. 2024 May; 4(3):e000978. Saber H, Froehler MT, Zaidat OO, Sultan AA, Klucznik RP, Saver JL, Sanossian N, Hellinger FR, Yavagal DR, Yao TL, Jahan R, Haussen DC, Nogueira RG, Hall AM, Kronast NHM, Liebeskind DS, STRATIS Investigators. PMID: 41584475; PMCID: PMC12778501.
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Trends in Stroke Thrombolysis Care Metrics and Outcomes by Race and Ethnicity, 2003-2021. JAMA Netw Open. 2024 02 05; 7(2):e2352927. Man S, Solomon N, Mac Grory B, Alhanti B, Saver JL, Smith EE, Xian Y, Bhatt DL, Schwamm LH, Uchino K, Fonarow GC. PMID: 38324315; PMCID: PMC10851100.
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Subarachnoid Hemorrhage Trials: Cutting, Sliding, or Keeping mRS Scores and WFNS Grades. Stroke. 2024 03; 55(3):779-784. Mistry AM, Saver J, Mack W, Kamel H, Elm J, Beall J. PMID: 38235584; PMCID: PMC11186115.
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Effects of tirofiban on large vessel occlusion stroke are modified by etiology and renal function. Ann Clin Transl Neurol. 2024 Mar; 11(3):618-628. Liu C, Li F, Chen L, Huang J, Sang H, Nguyen TN, Saver JL, Abdalkader M, Kong W, Yang J, Guo C, Gong C, Huang L, Pan Y, Wang X, Chen Y, Qiu Z, Zi W. PMID: 38156359; PMCID: PMC10963294.
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Magnesium and Hematoma Expansion in Intracerebral Hemorrhage: A FAST-MAG Randomized Trial Analysis. Stroke. 2024 02; 55(2):463-466. Liotta EM, Maas MB, Prabhakaran S, Shkirkova K, Sanossian N, Liebeskind DS, Sharma L, Stratton S, Conwit R, Saver JL, FAST-MAG Investigators and Coordinators. PMID: 38126183; PMCID: PMC10872280.
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Update on the INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): progress and baseline features in 2053 participants. Trials. 2023 Dec 20; 24(1):817. Chen C, Lin Y, Liu F, Chen X, Billot L, Li Q, Guo Y, Liu H, Si L, Ouyang M, Zhang C, Arima H, Bath PM, Ford GA, Robinson T, Sandset EC, Saver JL, Sprigg N, van der Worp HB, Liu G, Song L, Yang J, Li G, Anderson CS, INTERACT4 Investigators. PMID: 38124205; PMCID: PMC10731692.
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The role of intravenous thrombolysis before mechanical Thrombectomy: A subgroup analysis of the RESILIENT trial. J Neurol Sci. 2024 02 15; 457:122853. Silva GS, Alves MM, Barros FCD, Frudit ME, Pontes-Neto OM, Mont'Alverne FJ, Rebello LC, Carbonera LA, Abud DG, Lima F, de Souza AC, Liebeskind D, Mosmann G, Bezerra D, Saver J, Cardoso F, Nogueira RG, Martins SO. PMID: 38182456.
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Corrigendum: Staged use of ordinal and linear disability scales: a practical approach to granular assessment of acute stroke outcome. Front Neurol. 2023; 14:1331276. Chaisinanunkul N, Starkman S, Gornbein J, Hamilton S, Chatfield F, Conwit R, Saver JL. PMID: 38152646; PMCID: PMC10751782.
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Patent Foramen Ovale Management for Secondary Stroke Prevention: State-of-the-Art Appraisal of Current Evidence. Stroke. 2024 01; 55(1):236-247. Sposato LA, Albin CSW, Elkind MSV, Kamel H, Saver JL. PMID: 38134261.
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Large vessel occlusion prediction scale thresholds that are sensitive for DAWN Trial patients. Interv Neuroradiol. 2025 Dec; 31(6):795-803. Keenan KJ, Smith WS, Jadhav AP, Haussen DC, Budzik RF, Bonafé A, Bhuva P, Yavagal DR, Ribò M, Cognard C, Hanel RA, Hassan AE, Sila CA, Saver JL, Liebeskind DS, Jovin TG, Nogueira RG. PMID: 37915142; PMCID: PMC12602885.
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Clinically important effect sizes for clinical trials using infarct growth reduction as the primary outcome: a systematic review. J Neurointerv Surg. 2023 Oct 31. Liao NC, Bahr Hosseini M, Saver JL. PMID: 37907282.
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Strokes Averted by Intravenous Thrombolysis: A Secondary Analysis of a Prospective, Multicenter, Controlled Trial of Mobile Stroke Units. Ann Neurol. 2024 Feb; 95(2):347-361. Navi BB, Bach I, Czap AL, Wang M, Yamal JM, Jacob AP, Parker SA, Rajan SS, Mir S, Sherman C, Willey JZ, Saver JL, Gonzalez MO, Singh N, Jones WJ, Ornelas D, Gonzales NR, Alexandrov AW, Alexandrov AV, Nour M, Spokoyny I, Mackey J, Collins SQ, Silnes K, Fink ME, English J, Barazangi N, Bratina PL, Volpi J, Rao CPV, Griffin L, Persse D, Grotta JC. PMID: 37801480.
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Performance of Thrombectomy-Capable, Comprehensive, and Primary Stroke Centers in Reperfusion Therapies for Acute Ischemic Stroke: Report From the Get With The Guidelines-Stroke Registry. Circulation. 2023 12 19; 148(25):2019-2028. Raychev R, Sun JL, Schwamm L, Smith EE, Fonarow GC, Messé SR, Xian Y, Chiswell K, Blanco R, Mac Grory B, Saver JL. PMID: 37855118.
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Perfusion Collateral Index versus Hypoperfusion Intensity Ratio in Assessment of Collaterals in Patients with Acute Ischemic Stroke. AJNR Am J Neuroradiol. 2023 11; 44(11):1249-1255. Tsui B, Chen IE, Nour M, Kihira S, Tavakkol E, Polson J, Zhang H, Qiao J, Bahr-Hosseini M, Arnold C, Tateshima S, Salamon N, Villablanca JP, Colby GP, Jahan R, Duckwiler G, Saver JL, Liebeskind DS, Nael K. PMID: 37827719; PMCID: PMC10631520.
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Subarachnoid Hemorrhage Trials: Cutting, Sliding, or Keeping mRS Scores and WFNS Grades. medRxiv. 2023 Oct 02. Mistry AM, Saver J, Mack W, Kamel H, Elm J, Beall J. PMID: 37873354; PMCID: PMC10593043.
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Effect of Endovascular Treatment in HERMES Patients With Isolated Occlusion of the Intracranial Internal Carotid Artery. Stroke Vasc Interv Neurol. 2023 Nov; 3(6):e001025. Kaiser DPO, Nguyen TN, Campbell BCV, Saver JL, Dippel DWJ, Demchuk AM, Majoie CBLM, Brown SB, Mitchell PJ, Gerber JC, Bracard S, Guillemin F, Jovin TG, Muir KW, White P, Schoene D, Hill MD, Goyal M, Puetz V, HERMES Collaborators. PMID: 41585058; PMCID: PMC12778729.
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Intravenous tirofiban following successful reperfusion in intracranial large artery atherosclerotic stroke: A secondary analysis of a randomized clinical trial. Ann Clin Transl Neurol. 2023 11; 10(11):2043-2052. Huang J, Kong W, Liu C, Song J, Yang J, Yue C, Li L, Hu J, Tian Y, Peng Z, Guo C, Yang D, Liu X, Miao J, Zhang X, Li F, Saver JL, Zi W. PMID: 37649303; PMCID: PMC10646994.
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Association of the time of day of EVT with clinical outcomes and benefit from successful recanalization after stroke. Ann Clin Transl Neurol. 2023 10; 10(10):1917-1923. Burbano VG, Wölfer TA, Vlegels N, Quandt F, Zimmermann H, Wischmann J, Kellert L, Liebig T, Dimitriadis K, Saver JL, Tiedt S, GSR investigators. PMID: 37607113; PMCID: PMC10578882.
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Optimizing Patient-Centered Stroke Care and Research in the Prehospital Setting. Stroke. 2023 09; 54(9):2453-2460. Fladt J, Ospel JM, Singh N, Saver JL, Fisher M, Goyal M. PMID: 37548010.
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Development and Validation of a Postprocedural Model to Predict Outcome After Endovascular Treatment for Ischemic Stroke. JAMA Neurol. 2023 Jul 31. Chalos V, Venema E, Mulder MJHL, Roozenbeek B, Steyerberg EW, Wermer MJH, Lycklama À Nijeholt GJ, van der Worp HB, Goyal M, Campbell BCV, Muir KW, Guillemin F, Bracard S, White P, Dávalos A, Jovin TG, Hill MD, Mitchell PJ, Demchuk AM, Saver JL, van der Lugt A, Brown S, Dippel DWJ, Lingsma HF, HERMES CollaboratorsMR CLEAN Registry Investigators. PMID: 37523199; PMCID: PMC10391355.
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Performance of Thrombectomy-Capable, Comprehensive, and Primary Stroke Centers in Reperfusion Therapies for Acute Ischemic Stroke: Report from the Get With The Guidelines Stroke Registry: Stroke Outcomes Per Hospital Certification Status. medRxiv. 2023 Jul 06. Raychev R, Sun JL, Schwamm L, Smith EE, Fonarow GC, Messé SR, Xian Y, Chiswell K, Blanco R, Mac Grory B, Saver JL. PMID: 37461517; PMCID: PMC10350146.
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Outcomes of patients with pre-existing disability managed by mobile stroke units: A sub-analysis of the BEST-MSU study. Int J Stroke. 2023 12; 18(10):1209-1218. Pirlog BO, Jacob AP, Rajan SS, Yamal JM, Parker SA, Wang M, Bowry R, Czap A, Bratina PL, Gonzalez MO, Singh N, Zou J, Gonzales NR, Jones WJ, Alexandrov AW, Alexandrov AV, Navi BB, Nour M, Spokoyny I, Mackey J, Silnes K, Fink ME, Pisarro Sherman C, Willey J, Saver JL, English J, Barazangi N, Ornelas D, Volpi J, Pv Rao C, Griffin L, Persse D, Grotta JC. PMID: 37337357.
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Modified Rankin Scale Disability Status at Day 4 Poststroke is an Informative Predictor of Long-Term Day 90 Outcome. medRxiv. 2023 Jul 01. Taleb S, Lee JJ, Asanad S, Starkman S, Hamilton S, Conwit RA, Sanossian N, Saver JL. PMID: 37425918; PMCID: PMC10327286.
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Staged use of ordinal and linear disability scales: a practical approach to granular assessment of acute stroke outcome. Front Neurol. 2023; 14:1174686. Chaisinanunkul N, Starkman S, Gornbein J, Hamilton S, Chatfield F, Conwit R, Saver JL. PMID: 37456628; PMCID: PMC10344771.
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Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): effects on outcomes at day 365 in a randomised, sham-controlled, blinded, phase III, superiority ambulance-based trial. BMJ Neurol Open. 2023; 5(1):e000424. Woodhouse LJ, Appleton JP, Ankolekar S, England TJ, Mair G, Muir K, Price CI, Pocock S, Randall M, Robinson TG, Roffe C, Sandset EC, Saver JL, Siriwardena AN, Sprigg N, Wardlaw JM, Bath PM, RIGHT-2 Investigators. PMID: 37564156; PMCID: PMC10410995.
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Recent Vitamin K Antagonist Use and Intracranial Hemorrhage After Endovascular Thrombectomy for Acute Ischemic Stroke. JAMA. 2023 06 20; 329(23):2038-2049. Mac Grory B, Holmes DN, Matsouaka RA, Shah S, Chang CWJ, Rison R, Jindal J, Holmstedt C, Logan WR, Corral C, Mackey JS, Gee JR, Bonovich D, Walker J, Gropen T, Benesch C, Dissin J, Pandey H, Wang D, Unverdorben M, Hernandez AF, Reeves M, Smith EE, Schwamm LH, Bhatt DL, Saver JL, Fonarow GC, Peterson ED, Xian Y. PMID: 37338878; PMCID: PMC10282891.
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Essential information for neurorecovery clinical trial design: trajectory of global disability in first 90 days post-stroke in patients discharged to acute rehabilitation facilities. BMC Neurol. 2023 Jun 20; 23(1):239. Taleb S, Lee JJ, Duncan P, Cramer SC, Bahr-Hosseini M, Su M, Starkman S, Avila G, Hochberg A, Hamilton S, Conwit RA, Saver JL. PMID: 37340330; PMCID: PMC10280859.
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Consensus Recommendations for Standardized Data Elements, Scales, and Time Segmentations in Studies of Human Circadian/Diurnal Biology and Stroke. Stroke. 2023 07; 54(7):1943-1949. Saver JL, Klerman EB, Buchan AM, Calleja P, Lizasoain I, Bahr-Hosseini M, Lee S, Liebeskind DS, Mergenthaler P, Mun KT, Ning M, Pelz D, Ray D, Rothwell PM, Seners P, Sreekrishnan A, Sung EM, Tiedt S, Webb AJS, Wölfer TA, Albers GW, Leducq Consortium International pour la Recherche Circadienne sur l’AVC Effects in Stroke (CIRCA). PMID: 37272394.
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Mechanical Thrombectomy for Large Ischemic Stroke: A Systematic Review and Meta-analysis. Neurology. 2023 08 29; 101(9):e922-e932. Li Q, Abdalkader M, Siegler JE, Yaghi S, Sarraj A, Campbell BCV, Yoo AJ, Zaidat OO, Kaesmacher J, Pujara D, Nogueira RG, Saver JL, Li L, Han Q, Dai Y, Sang H, Yang Q, Nguyen TN, Qiu Z. PMID: 37277200; PMCID: PMC10501098.
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Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion. N Engl J Med. 2023 06 01; 388(22):2025-2036. Zi W, Song J, Kong W, Huang J, Guo C, He W, Yu Y, Zhang B, Geng W, Tan X, Tian Y, Liu Z, Cao M, Cheng D, Li B, Huang W, Liu J, Wang P, Yu Z, Liang H, Yang S, Tang M, Liu W, Huang X, Liu S, Tang Y, Wu Y, Yao L, Shi Z, He P, Zhao H, Chen Z, Luo J, Wan Y, Shi Q, Wang M, Chen X, Huang F, Mu J, Li H, Li Z, Zheng J, Xie S, Cai T, Peng Y, Xie W, Qiu Z, Liu C, Yue C, Li L, Tian Y, Yang D, Miao J, Yang J, Hu J, Nogueira RG, Wang D, Saver JL, Li F, Yang Q, RESCUE BT2 Investigators. PMID: 37256974.
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High-definition Cathodal Direct Current Stimulation for Treatment of Acute Ischemic Stroke: A Randomized Clinical Trial. JAMA Netw Open. 2023 06 01; 6(6):e2319231. Bahr-Hosseini M, Nael K, Unal G, Iacoboni M, Liebeskind DS, Bikson M, Saver JL, TESSERACT Trial Group. PMID: 37342040; PMCID: PMC10285579.
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Shorter Door-to-Needle Times Are Associated With Better Outcomes After Intravenous Thrombolytic Therapy and Endovascular Thrombectomy for Acute Ischemic Stroke. Circulation. 2023 07 04; 148(1):20-34. Man S, Solomon N, Mac Grory B, Alhanti B, Uchino K, Saver JL, Smith EE, Xian Y, Bhatt DL, Schwamm LH, Hussain MS, Fonarow GC. PMID: 37199147; PMCID: PMC10356148.
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Effect of Imaging Selection Paradigms on Endovascular Thrombectomy Outcomes in Patients With Acute Ischemic Stroke. Stroke. 2023 06; 54(6):1569-1577. Miao J, Sang H, Li F, Saver JL, Lei B, Li J, Nogueira RG, Song B, Liu S, Nguyen TN, Jin Z, Zeng H, Wen C, Yuan G, Kong W, Luo W, Liu S, Xie D, Huang J, Liu C, Yang J, Hu J, Song J, Yue C, Li L, Tian Y, Zhang X, Feng D, Gao Y, Fu H, Zi W, Yang Q, Qiu Z, Wang S. PMID: 37165864.
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Corrigendum: How often is occult atrial fibrillation in cryptogenic stroke causal vs. incidental? A meta-analysis. Front Neurol. 2023; 14:1206563. Chaisinanunkul N, Khurshid S, Buck BH, Rabinstein AA, Anderson CD, Hill MD, Fugate JE, Saver JL. PMID: 37234786; PMCID: PMC10206386.
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EMAGINE-Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke. Front Neurol. 2023; 14:1148074. Saver JL, Duncan PW, Stein J, Cramer SC, Eng JJ, Lifshitz A, Hochberg A, Bornstein NM. PMID: 37213907; PMCID: PMC10196621.
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Association Between Magnitude of Differential Blood Pressure Reduction and Secondary Stroke Prevention: A Meta-analysis and Meta-Regression. JAMA Neurol. 2023 05 01; 80(5):506-515. Hsu CY, Saver JL, Ovbiagele B, Wu YL, Cheng CY, Lee M. PMID: 36939729; PMCID: PMC10028545.
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Circadian variation in stroke onset: Differences between ischemic and hemorrhagic stroke and weekdays versus weekends. J Stroke Cerebrovasc Dis. 2023 Jul; 32(7):107106. Pariona-Vargas F, Mun KT, Lo EH, Starkman S, Sanossian N, Hosseini MB, Stratton S, Eckstein M, Conwit RA, Liebeskind DS, Sharma LK, Rao NM, Shkirkova K, Avila G, Kim-Tenser MA, Saver JL, FAST-MAG Investigators. PMID: 37116446.
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Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines. Curr Neurol Neurosci Rep. 2023 05; 23(5):235-262. Bhatia K, Ladd LM, Carr KH, Di Napoli M, Saver JL, McCullough LD, Hosseini Farahabadi M, Alsbrook DL, Hinduja A, Ortiz Garcia JG, Sabbagh SY, Jafarli A, Divani AA. PMID: 37037980.
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Association of inferior division MCA stroke location with populations with atrial fibrillation incidence. Heliyon. 2023 Apr; 9(4):e15287. Kim G, Vitti E, Stockbridge MD, Saver JL, Hillis AE, Faria AV. PMID: 37089357; PMCID: PMC10113841.
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Plasma CGRP Levels Are Not Associated With Collateral Flow and Outcome After Stroke. Stroke. 2023 05; 54(5):e203-e204. Bahr-Hosseini M, Meißner N, Reidler P, Saver JL, Tiedt S. PMID: 37013820.
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Association of Tirofiban With Functional Outcomes After Thrombectomy in Acute Ischemic Stroke Due to Intracranial Atherosclerotic Disease. Neurology. 2023 05 09; 100(19):e1996-e2006. Sang H, Xie D, Tian Y, Nguyen TN, Saver JL, Nogueira RG, Wu J, Long C, Tian Z, Hu Z, Wang T, Li R, Ke Y, Zhu X, Peng D, Chang M, Li L, Ruan J, Wu D, Zi W, Yang Q, Li F, Qiu Z. PMID: 36941074; PMCID: PMC10186214.
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How often is occult atrial fibrillation in cryptogenic stroke causal vs. incidental? A meta-analysis. Front Neurol. 2023; 14:1103664. Chaisinanunkul N, Khurshid S, Buck BH, Rabinstein AA, Anderson CD, Hill MD, Fugate JE, Saver JL. PMID: 36998779; PMCID: PMC10043201.
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Mechanical Thrombectomy Global Access For Stroke (MT-GLASS): A Mission Thrombectomy (MT-2020 Plus) Study. Circulation. 2023 04 18; 147(16):1208-1220. Asif KS, Otite FO, Desai SM, Herial N, Inoa V, Al-Mufti F, Jadhav AP, Dmytriw AA, Castonguay A, Khandelwal P, Potter-Vig J, Szeder V, Kulman T, Urrutia V, Masoud H, Toth G, Limaye K, Aroor S, Brinjikji W, Rai A, Pandian J, Gebreyohanns M, Leung T, Mansour O, Demchuk AM, Huded V, Martins S, Zaidat O, Huo X, Campbell B, Sylaja PN, Miao Z, Saver J, Ortega-Gutierrez S, Yavagal DR, Global Executive Committee of the MT-GLASS Study. PMID: 36883458.
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Using Epidemiological Data to Inform Clinical Trial Feasibility Assessments: A Case Study. Stroke. 2023 04; 54(4):1009-1014. Stanton RJ, Robinson DJ, Aziz YN, Sucharew H, Khatri P, Broderick JP, Janis LS, Kemp S, Mlynash M, Lansberg MG, Albers GW, Saver JL, Flaherty ML, Adeoye O, Woo D, Ferioli S, Kissela BM, Kleindorfer DO. PMID: 36852687; PMCID: PMC10050115.
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Golden Hour Treatment With tPA (Tissue-Type Plasminogen Activator) in the BEST-MSU Study. Stroke. 2023 02; 54(2):415-425. Mackey J, Yamal JM, Parker SA, Silnes K, Rajan SS, Jacob AP, Wang M, Singh N, Jones WJ, Spokoyny I, Navi BB, Saver JL, Grotta JC, BEST-MSU Study Group. PMID: 36689579.
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Admission hyperglycemia, stroke subtypes, outcomes in acute ischemic stroke. Diabetes Res Clin Pract. 2023 Feb; 196:110257. Kim JT, Lee JS, Kim BJ, Kang J, Lee KJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Park TH, Lee KB, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Choi JC, Kwon JH, Kim WJ, Shin DI, Yum KS, Sohn SI, Hong JH, Lee SH, Park MS, Choi KH, Ryu WS, Lee J, Saver JL, Bae HJ. PMID: 36642337.
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Frequency of Thrombectomy in Early and Late Postonset Time Windows Among Emergency Medical Services Patients With Acute Ischemic Stroke. Stroke Vasc Interv Neurol. 2023 Mar; 3(2):e000519. Bosson N, Saver JL, Lyden PD, Gausche-Hill M. PMID: 41585918; PMCID: PMC12778611.
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Effect of Magnesium on Deterioration and Symptomatic Hemorrhagic Transformation in Cerebral Ischemia: An Ancillary Analysis of the FAST-MAG Trial. Cerebrovasc Dis. 2023; 52(5):539-542. Fan S, Jang M, Kim-Tenser M, Shkirkova K, Liebeskind DS, Starkman S, Villablanca JP, Hamilton S, Naidech A, Saver JL, Sanossian N, FAST-MAG Investigators and Coordinators. PMID: 36599321; PMCID: PMC10627486.
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Automated estimation of ischemic core volume on noncontrast-enhanced CT via machine learning. Interv Neuroradiol. 2025 Feb; 31(1):32-41. Chen IE, Tsui B, Zhang H, Qiao JX, Hsu W, Nour M, Salamon N, Ledbetter L, Polson J, Arnold C, BahrHossieni M, Jahan R, Duckwiler G, Saver J, Liebeskind D, Nael K. PMID: 36572984; PMCID: PMC11833852.
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Efficacy of endovascular therapy for basilar and vertebral artery occlusion: A systematic review and meta-analysis of randomized controlled trials. Eur J Intern Med. 2023 04; 110:22-28. Lin CH, Liebeskind DS, Ovbiagele B, Lee M, Saver JL. PMID: 36572580.
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Frequency, management, and outcomes of early neurologic deterioration due to stroke progression or recurrence. J Stroke Cerebrovasc Dis. 2023 Feb; 32(2):106940. Kim JT, Lee JS, Kim BJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Park TH, Lee KB, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Ryu WS, Choi JC, Kwon JH, Kim WJ, Shin DI, Yum KS, Sohn SI, Hong JH, Lee SH, Park MS, Choi KH, Lee J, Saver JL, Bae HJ. PMID: 36529099.
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RCT versus real-world cohorts: Differences in patient characteristics drive associations with outcome after EVT. Eur Stroke J. 2023 03; 8(1):231-240. Quandt F, Meißner N, Wölfer TA, Flottmann F, Deb-Chatterji M, Kellert L, Fiehler J, Goyal M, Saver JL, Gerloff C, Thomalla G, Tiedt S. PMID: 37021166; PMCID: PMC10069173.
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Lifetime economic potential of mobile stroke units in acute stroke care: A model-based analysis of the drivers of cost-effectiveness. J Telemed Telecare. 2024 Sep; 30(8):1335-1344. Rink JS, Froelich MF, Nour M, Saver JL, Szabo K, Hoyer C, Fassbender KC, Schoenberg SO, Tollens F. PMID: 36484406.
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Neurologic Improvement in Acute Cerebral Ischemia: Frequency, Magnitude, Predictors, and Clinical Outcomes. Neurology. 2023 03 07; 100(10):e1038-e1047. Balucani C, Levine SR, Sanossian N, Starkman S, Liebeskind D, Gornbein JA, Shkirkova K, Stratton S, Eckstein M, Hamilton S, Conwit R, Sharma LK, Saver JL. PMID: 36878722; PMCID: PMC9990857.
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Cost-Effectiveness of Endovascular Treatment in Large Vessel Occlusion Stroke With Mild Prestroke Disability: Results From the HERMES Collaboration. Stroke. 2023 01; 54(1):226-233. Ospel JM, Kunz WG, McDonough RV, van Zwam W, Pinckaers F, Saver JL, Hill MD, Demchuk AM, Jovin TG, Mitchell P, Campbell BCV, White P, Muir K, Achit H, Bracard S, Brown S, Goyal M, HERMES Investigators. PMID: 36472199.
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Association Between Hyperacute Blood Pressure Variability and Hematoma Expansion After Intracerebral Hemorrhage: Secondary Analysis of the FAST-MAG Database. Neurocrit Care. 2023 04; 38(2):356-364. Oh DM, Shkirkova K, Poblete RA, Chung PW, Saver JL, Starkman S, Liebeskind DS, Hamilton S, Wilson M, Sanossian N. PMID: 36471183.
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Modeling optimal patient transport in a stroke network capable of remote telerobotic endovascular therapy. Interv Neuroradiol. 2024 Aug; 30(4):506-516. Beaman C, Holodinsky JK, Goyal M, Tateshima S, Hill MD, Saver JL, Kamal N. PMID: 36398447; PMCID: PMC11475389.
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Frequency-tuned electromagnetic field therapy improves post-stroke motor function: A pilot randomized controlled trial. Front Neurol. 2022; 13:1004677. Weisinger B, Pandey DP, Saver JL, Hochberg A, Bitton A, Doniger GM, Lifshitz A, Vardi O, Shohami E, Segal Y, Reznik Balter S, Djemal Kay Y, Alter A, Prasad A, Bornstein NM. PMID: 36452175; PMCID: PMC9702345.
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Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure. JAMA Neurol. 2022 11 01; 79(11):1175-1179. Mas JL, Saver JL, Kasner SE, Nelson J, Carroll JD, Chatellier G, Derumeaux G, Furlan AJ, Herrmann HC, Jüni P, Kim JS, Koethe B, Lee PH, Lefebvre B, Mattle HP, Meier B, Reisman M, Smalling RW, Sondergaard L, Song JK, Thaler DE, Kent DM. PMID: 36215079; PMCID: PMC9552048.
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Impact of ARUBA trial on trends and outcomes in symptomatic non-ruptured brain AVMs: A national sample analysis. J Stroke Cerebrovasc Dis. 2022 Dec; 31(12):106807. Patel SD, Saber H, Desai N, Otite FO, Kaneko N, Mehta TV, Hinman J, Hassan AE, Jadhav A, Liebeskind DS, Saver JL. PMID: 36272182.
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Comparison of Three Scores of Collateral Status for Their Association With Clinical Outcome: The HERMES Collaboration. Stroke. 2022 12; 53(12):3548-3556. Gensicke H, Al-Ajlan F, Fladt J, Campbell BCV, Majoie CBLM, Bracard S, Hill MD, Muir KW, Demchuk A, San Román L, van der Lugt A, Liebeskind DS, Brown S, White PM, Guillemin F, Dávalos A, Jovin TG, Saver JL, Dippel DWJ, Goyal M, Mitchell PJ, Menon BK, HERMES Collaborators. PMID: 36252099.
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Endovascular Therapy vs Medical Management for Patients With Acute Stroke With Medium Vessel Occlusion in the Anterior Circulation. JAMA Netw Open. 2022 10 03; 5(10):e2238154. Saber H, Desai SM, Haussen D, Al-Bayati A, Majidi S, Mocco J, Hassan AE, Rajah G, Waqas M, Davies JM, Dornbos D, Nickele C, Arthur AS, Mowla A, Tenser MS, Mokin M, Pressman E, Aghaebrahim A, Hanel RA, Ortega-Gutierrez S, Jovin T, Duckwiler GR, Liebeskind DS, Nogueira RG, Gornbein J, Saver JL, Jadhav AP. PMID: 36279137; PMCID: PMC9593229.
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Outcomes among patients with primary angiitis of the CNS: A Nationwide United States analysis. J Stroke Cerebrovasc Dis. 2022 Nov; 31(11):106747. Patel SD, Oliver FO, Elmashad A, Patel N, Mehta T, Hinman J, Liebeskind DS, Singhal AB, Ducros A, Saver JL. PMID: 36162376.
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Monitoring for atrial fibrillation prior to patent foramen ovale closure after cryptogenic stroke. Int J Stroke. 2023 04; 18(4):400-407. Diener HC, Wachter R, Wong A, Thijs V, Schnabel RB, Ntaios G, Kasner S, Rothwell PM, Passman R, Saver JL, Albers BA, Bernstein RA. PMID: 36050817; PMCID: PMC10037544.
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Does Capturing Debris during TAVR Prevent Strokes? N Engl J Med. 2022 10 06; 387(14):1318-1319. Carroll JD, Saver JL. PMID: 36121036.
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Quantifying the amount of greater brain ischemia protection time with pre-hospital vs. in-hospital neuroprotective agent start. Front Neurol. 2022; 13:990339. Matossian V, Starkman S, Sanossian N, Stratton S, Eckstein M, Conwit R, Liebeskind DS, Sharma L, Tenser MK, Saver JL. PMID: 36176566; PMCID: PMC9514007.
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Dual vs. mono antiplatelet therapy for acute ischemic stroke or transient ischemic attack with evidence of large artery atherosclerosis. Front Neurol. 2022; 13:923142. Lin CJ, Tseng TY, Saver JL. PMID: 36172029; PMCID: PMC9510375.
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RESCUE BT 2, a multicenter, randomized, double-blind, double-dummy trial of intravenous tirofiban in acute ischemic stroke: Study rationale and design. Int J Stroke. 2023 06; 18(5):620-625. Zi W, Song J, Qiu Z, Kong W, Huang J, Luo W, Liu S, Sang H, Yang J, Li L, Tian Y, Hu J, Saver JL, Nogueira RG, Li F, Yang Q. PMID: 35993176.
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Optimizing a Bayesian hierarchical adaptive platform trial design for stroke patients. Trials. 2022 Sep 06; 23(1):754. Gao G, Gajewski BJ, Wick J, Beall J, Saver JL, Meinzer C, STEP-STONE Executive Committee. PMID: 36068547; PMCID: PMC9446515.
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MR Angiography in Assessment of Collaterals in Patients with Acute Ischemic Stroke: A Comparative Analysis with Digital Subtraction Angiography. Brain Sci. 2022 Sep 02; 12(9). Tsui B, Nour M, Chen I, Qiao JX, Salehi B, Yoo B, Colby GP, Salamon N, Villablanca P, Jahan R, Duckwiler G, Saver JL, Liebeskind DS, Nael K. PMID: 36138917; PMCID: PMC9497115.
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The Correlation between COVID-19 Hospitalizations and Emergency Medical Services Responses for Time-Sensitive Emergencies during the COVID-19 Pandemic. Prehosp Emerg Care. 2023; 27(3):321-327. Bosson N, Rollman JE, Kloner RA, Shavelle DM, Saver JL, Niemann JT, Rafique AM, Wang X, Clare C, Gausche-Hill M. PMID: 35969017.
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Mechanical Thrombectomy for Acute Ischemic Stroke in Patients With Dementia. Stroke Vasc Interv Neurol. 2022 Sep; 2(5):e000164. Saber H, Hinman J, Mun K, Kaneko N, Szeder V, Tateshima S, Nour M, Raychev R, Ooi YC, Jahan R, Duckwiler GP, Saver JL, Liebeskind DS. PMID: 41584004; PMCID: PMC12778819.
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Interventional compared with medical management of symptomatic carotid web: A systematic review. J Stroke Cerebrovasc Dis. 2022 Oct; 31(10):106682. Patel SD, Otite FO, Topiwala K, Saber H, Kaneko N, Sussman E, Mehta TV, Tummala R, Hinman J, Nogueira R, Haussen DC, Liebeskind DS, Saver JL. PMID: 35998383.
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Effect of Intravenous Tirofiban vs Placebo Before Endovascular Thrombectomy on Functional Outcomes in Large Vessel Occlusion Stroke: The RESCUE BT Randomized Clinical Trial. JAMA. 2022 08 09; 328(6):543-553. RESCUE BT Trial Investigators, Qiu Z, Li F, Sang H, Luo W, Liu S, Liu W, Guo Z, Li H, Sun D, Huang W, Zhang M, Zhang M, Dai W, Zhou P, Deng W, Zhou Z, Huang X, Lei B, Li J, Yuan Z, Song B, Miao J, Liu S, Jin Z, Zeng G, Zeng H, Yuan J, Wen C, Yu Y, Yuan G, Wu J, Long C, Luo J, Tian Z, Zheng C, Hu Z, Wang S, Wang T, Qi L, Li R, Wan Y, Ke Y, Wu Y, Zhu X, Kong W, Huang J, Peng D, Chang M, Ge H, Shi Z, Yan Z, Du J, Jin Y, Ju D, Huang C, Hong Y, Liu T, Zhao W, Wang J, Zheng B, Wang L, Liu S, Luo X, Luo S, Xu X, Hu J, Pu J, Chen S, Sun Y, Jiang S, Wei L, Fu X, Bai Y, Yang S, Hu W, Zhang G, Pan C, Zhang S, Wang Y, Cao W, Yang S, Zhang J, Guo F, Wen H, Zhang J, Song J, Yue C, Li L, Wu D, Tian Y, Yang J, Lu M, Saver JL, Nogueira RG, Zi W, Yang Q. PMID: 35943471; PMCID: PMC9364124.
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Outcomes After Endovascular Thrombectomy With or Without Alteplase in Routine Clinical Practice. JAMA Neurol. 2022 08 01; 79(8):768-776. Smith EE, Zerna C, Solomon N, Matsouaka R, Mac Grory B, Saver JL, Hill MD, Fonarow GC, Schwamm LH, Messé SR, Xian Y. PMID: 35696198; PMCID: PMC9194745.
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Time to treatment with bridging intravenous alteplase before endovascular treatment:subanalysis of the randomized controlled SWIFT-DIRECT trial. J Neurointerv Surg. 2023 Sep; 15(e1):e102-e110. Meinel TR, Kaesmacher J, Buetikofer L, Strbian D, Eker OF, Cognard C, Mordasini P, Deppeler S, Mendes Pereira V, Albucher JF, Darcourt J, Bourcier R, Guillon B, Papagiannaki C, Costentin G, Sibolt G, Räty S, Gory B, Richard S, Liman J, Ernst M, Boulanger M, Barbier C, Mechtouff L, Zhang L, Marnat G, Sibon I, Nikoubashman O, Reich A, Consoli A, Weisenburger D, Requena M, Garcia-Tornel A, Saleme S, Moulin S, Pagano P, Saliou G, Carrera E, Janot K, Boix M, Pop R, Della Schiava L, Luft A, Piotin M, Gentric JC, Pikula A, Pfeilschifter W, Arnold M, Siddiqui A, Froehler MT, Furlan AJ, Chapot R, Wiesmann M, Machi P, Diener HC, Kulcsar Z, Bonati L, Bassetti C, Escalard S, Liebeskind D, Saver JL, Fischer U, Gralla J, SWIFT-DIRECT investigators. PMID: 35902234; PMCID: PMC10715486.
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Sex Differences in Endovascular Therapy for Ischemic Stroke: Results From the Get With The Guidelines-Stroke Registry. Stroke. 2022 10; 53(10):3099-3106. Demel SL, Reeves M, Xu H, Xian Y, Mac Grory B, Fonarow GC, Matsouaka R, Smith EE, Saver J, Schwamm L. PMID: 35880521.
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Outcome Prediction Based on Automatically Extracted Infarct Core Image Features in Patients with Acute Ischemic Stroke. Diagnostics (Basel). 2022 Jul 23; 12(8). Tolhuisen ML, Hoving JW, Koopman MS, Kappelhof M, van Voorst H, Bruggeman AE, Demchuck AM, Dippel DWJ, Emmer BJ, Bracard S, Guillemin F, van Oostenbrugge RJ, Mitchell PJ, van Zwam WH, Hill MD, Roos YBWEM, Jovin TG, Berkhemer OA, Campbell BCV, Saver J, White P, Muir KW, Goyal M, Marquering HA, Majoie CB, Caan MWA, MR CLEAN-NO IV and HERMES investigators. PMID: 35892499; PMCID: PMC9331690.
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How can imaging in acute ischemic stroke help us to understand tissue fate in the era of endovascular treatment and cerebroprotection? Neuroradiology. 2022 09; 64(9):1697-1707. Goyal M, McTaggart R, Ospel JM, van der Lugt A, Tymianski M, Wiest R, Lundberg J, von Kummer R, Hill MD, Luijten S, Roozenbeek B, Saver JL, McDonough RV. PMID: 35854136.
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Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet. 2022 07 09; 400(10346):104-115. Fischer U, Kaesmacher J, Strbian D, Eker O, Cognard C, Plattner PS, Bütikofer L, Mordasini P, Deppeler S, Pereira VM, Albucher JF, Darcourt J, Bourcier R, Benoit G, Papagiannaki C, Ozkul-Wermester O, Sibolt G, Tiainen M, Gory B, Richard S, Liman J, Ernst MS, Boulanger M, Barbier C, Mechtouff L, Zhang L, Marnat G, Sibon I, Nikoubashman O, Reich A, Consoli A, Lapergue B, Ribo M, Tomasello A, Saleme S, Macian F, Moulin S, Pagano P, Saliou G, Carrera E, Janot K, Hernández-Pérez M, Pop R, Schiava LD, Luft AR, Piotin M, Gentric JC, Pikula A, Pfeilschifter W, Arnold M, Siddiqui AH, Froehler MT, Furlan AJ, Chapot R, Wiesmann M, Machi P, Diener HC, Kulcsar Z, Bonati LH, Bassetti CL, Mazighi M, Liebeskind DS, Saver JL, Gralla J, SWIFT DIRECT Collaborators. PMID: 35810756.
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Functional Outcomes of Patients ≥85 Years With Acute Ischemic Stroke Following EVT: A HERMES Substudy. Stroke. 2022 07; 53(7):2220-2226. McDonough RV, Ospel JM, Campbell BCV, Hill MD, Saver JL, Dippel DWJ, Demchuk AM, Majoie CBLM, Brown SB, Mitchell PJ, Bracard S, Guillemin F, Jovin TG, Muir KW, White P, Goyal M, HERMES Collaborators. PMID: 35703094.
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Machine Learning-Based Identification of Target Groups for Thrombectomy in Acute Stroke. Transl Stroke Res. 2023 06; 14(3):311-321. Quandt F, Flottmann F, Madai VI, Alegiani A, Küpper C, Kellert L, Hilbert A, Frey D, Liebig T, Fiehler J, Goyal M, Saver JL, Gerloff C, Thomalla G, Tiedt S, GSR investigators and the VISTA-Endovascular Collaborators. PMID: 35670996; PMCID: PMC10159968.
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Trends in Use, Outcomes, and Disparities in Endovascular Thrombectomy in US Patients With Stroke Aged 80 Years and Older Compared With Younger Patients. JAMA Netw Open. 2022 06 01; 5(6):e2215869. Adcock AK, Schwamm LH, Smith EE, Fonarow GC, Reeves MJ, Xu H, Matsouaka RA, Xian Y, Saver JL. PMID: 35671055; PMCID: PMC9175073.
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A Deep Learning-Based Automatic Collateral Assessment in Patients with Acute Ischemic Stroke. Transl Stroke Res. 2023 02; 14(1):66-72. Kim YC, Chung JW, Bang OY, Hong M, Seo WK, Kim GM, Yeop Kim E, Lee JS, Hong JM, Liebeskind DS, Saver JL. PMID: 35596910.
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Endovascular therapy might be a treatment option for mild stroke due to proximal occlusions but not M2 occlusions. J Neurointerv Surg. 2023 04; 15(4):409. Lin CH, Saver JL, Lee M. PMID: 35580982.
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Improving Visualization Methods of Utility-Weighted Disability Outcomes for Stroke Trials. Front Neurol. 2022; 13:875350. Tokunboh I, Sung EM, Chatfield F, Gaines N, Nour M, Starkman S, Saver JL. PMID: 35645952; PMCID: PMC9136165.
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Beyond the Golden Hour: Treating Acute Stroke in the Platinum 30 Minutes. Stroke. 2022 08; 53(8):2426-2434. Randhawa AS, Pariona-Vargas F, Starkman S, Sanossian N, Liebeskind DS, Avila G, Stratton S, Gornbein J, Sharma L, Restrepo-Jimenez L, Valdes-Sueiras M, Kim-Tenser M, Villablanca P, Conwit R, Hamilton S, Saver JL. PMID: 35545939; PMCID: PMC9329219.
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Fragility Index Meta-Analysis of Randomized Controlled Trials Shows Highly Robust Evidential Strength for Benefit of <3 Hour Intravenous Alteplase. Stroke. 2022 06; 53(6):2069-2074. Mun KT, Bonomo JB, Liebeskind DS, Saver JL. PMID: 35543129.
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Outcome prediction in large vessel occlusion ischemic stroke with or without endovascular stroke treatment: THRIVE-EVT. Int J Stroke. 2023 03; 18(3):331-337. Flint AC, Chan SL, Edwards NJ, Rao VA, Klingman JG, Nguyen-Huynh MN, Yan B, Mitchell PJ, Davis SM, Campbell BC, Dippel DW, Roos YB, van Zwam WH, Saver JL, Kidwell CS, Hill MD, Goyal M, Demchuk AM, Bracard S, Bendszus M, Donnan GA. PMID: 35319310.
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Correlation Between Computed Tomography-Based Tissue Net Water Uptake and Volumetric Measures of Cerebral Edema After Reperfusion Therapy. Stroke. 2022 08; 53(8):2628-2636. Ng FC, Yassi N, Sharma G, Brown SB, Goyal M, Majoie CBLM, Jovin TG, Hill MD, Muir KW, Saver JL, Guillemin F, Demchuk AM, Menon BK, San Roman L, White P, van der Lugt A, Ribo M, Bracard S, Mitchell PJ, Davis SM, Sheth KN, Kimberly WT, Campbell BCV, HERMES Collaborators. PMID: 35450438.
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Time to recognize three classes of non-inferiority trial margins. J Neurointerv Surg. 2023 01; 15(1):2-4. Saver JL, Mistry E. PMID: 35459714.
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Treatment Effects in Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale-Reply. JAMA. 2022 04 12; 327(14):1403. Kent DM, Saver JL, Thaler DE. PMID: 35412566.
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Magnesium Sulfate and Hematoma Expansion: An Ancillary Analysis of the FAST-MAG Randomized Trial. Stroke. 2022 05; 53(5):1516-1519. Naidech AM, Shkirkova K, Villablanca JP, Sanossian N, Liebeskind DS, Sharma L, Eckstein M, Stratton S, Conwit R, Hamilton S, Saver JL, FAST-MAG Investigators and Coordinators. PMID: 35380053; PMCID: PMC9038696.
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Cost-Effectiveness Analysis of Encephaloduroarteriosynangiosis Surgery for Symptomatic Intracranial Atherosclerotic Disease. Neurosurgery. 2022 04 01; 90(4):495-500. Gonzalez NR, Quintero-Consuegra MD, Chan JL, Chang D, Tseng CH, Saver JL. PMID: 35289774; PMCID: PMC9514743.
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Effects of endovascular therapy for mild stroke due to proximal or M2 occlusions: meta-analysis. J Neurointerv Surg. 2023 Apr; 15(4):350-354. Lin CH, Saver JL, Ovbiagele B, Tang SC, Lee M, Liebeskind DS. PMID: 35292565; PMCID: PMC10086511.
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Lessons Learned From the Historical Trends on Thrombolysis Use for Acute Ischemic Stroke Among Medicare Beneficiaries in the United States. Front Neurol. 2022; 13:827965. Meng T, Trickey AW, Harris AHS, Matheson L, Rosenthal S, Traboulsi AA, Saver JL, Wagner T, Govindarajan P. PMID: 35309566; PMCID: PMC8931506.
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Challenges and opportunities in research funding for neurovascular diseases from a clinical researcher's perspective. Interv Neuroradiol. 2023 Aug; 29(4):343-350. Ospel JM, McDonough R, Ganesh A, Sehgal A, Kappelhof M, Kashani N, Klijn CJ, Hill M, Saver J, Goyal M. PMID: 35238671; PMCID: PMC10399510.
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Perceived acceptable uncertainty regarding comparability of endovascular treatment alone versus intravenous thrombolysis plus endovascular treatment. J Neurointerv Surg. 2023 Mar; 15(3):227-232. Kaesmacher J, Mujanovic A, Treurniet K, Kappelhof M, Meinel TR, Yang P, Liu J, Zhang Y, Zi W, Yang Q, Nogueira RG, Kimura K, Matsumaru Y, Suzuki K, Yan B, Mitchell PJ, Miao Z, Roos YBWEM, Majoie CBLM, Gralla J, Saver JL, Fischer U. PMID: 35232755; PMCID: PMC9985721.
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Temporal Trends in Racial and Ethnic Disparities in Endovascular Therapy in Acute Ischemic Stroke. J Am Heart Assoc. 2022 03 15; 11(6):e023212. Sheriff F, Xu H, Maud A, Gupta V, Vellipuram A, Fonarow GC, Matsouaka RA, Xian Y, Reeves M, Smith EE, Saver J, Rodriguez G, Cruz-Flores S, Schwamm LH. PMID: 35229659; PMCID: PMC9075329.
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Race-Ethnic Disparities in Rates of Declination of Thrombolysis for Stroke. Neurology. 2022 04 19; 98(16):e1596-e1604. Mendelson SJ, Zhang S, Matsouaka R, Xian Y, Shah S, Lytle BL, Solomon N, Schwamm LH, Smith EE, Saver JL, Fonarow G, Holl J, Prabhakaran S. PMID: 35228335; PMCID: PMC9052571.
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Clinical outcome of patients with mild pre-stroke morbidity following endovascular treatment: a HERMES substudy. J Neurointerv Surg. 2023 Mar; 15(3):214-220. McDonough RV, Ospel JM, Majoie CBLM, Saver JL, White P, Dippel DWJ, Brown SB, Demchuk AM, Jovin TG, Mitchell PJ, Bracard S, Campbell BCV, Muir KW, Hill MD, Guillemin F, Goyal M, HERMES collaborators. PMID: 35210331.
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Association of Recent Use of Non-Vitamin K Antagonist Oral Anticoagulants With Intracranial Hemorrhage Among Patients With Acute Ischemic Stroke Treated With Alteplase. JAMA. 2022 02 22; 327(8):760-771. Kam W, Holmes DN, Hernandez AF, Saver JL, Fonarow GC, Smith EE, Bhatt DL, Schwamm LH, Reeves MJ, Matsouaka RA, Khan YM, Unverdorben M, Birmingham MC, Lyden PD, Asimos AW, Altschul D, Schoonover TL, Jumaa MA, Nomura JT, Suri MFK, Moore SA, Lafranchise EF, Olson D, Peterson ED, Xian Y. PMID: 35143601; PMCID: PMC8832308.
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Risk factors of unexplained early neurological deterioration after treatment for ischemic stroke due to large vessel occlusion: a post hoc analysis of the HERMES study. J Neurointerv Surg. 2023 Mar; 15(3):221-226. Bourcier R, Goyal M, Muir KW, Desal H, Dippel DWJ, Majoie CBLM, van Zwam WH, Jovin TG, Mitchell PJ, Demchuk AM, van Oostenbrugge RJ, Brown SB, Campbell B, White P, Hill MD, Saver JL, Weimar C, Jahan R, Guillemin F, Bracard S, Naggara O, HERMES Trialists Collaboration. PMID: 35169030.
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National Institutes of Health Stroke Scale Correlates Well with Initial Intracerebral Hemorrhage Volume. J Stroke Cerebrovasc Dis. 2022 Apr; 31(4):106348. Farooq S, Shkirkova K, Villablanca P, Sanossian N, Liebeskind DS, Starkman S, Avila G, Sharma L, Kim-Tenser M, Gasparian S, Eckstein M, Conwit R, Hamilton S, Saver JL. PMID: 35152129.
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Association of ischemic stroke onset time with presenting severity, acute progression, and long-term outcome: A cohort study. PLoS Med. 2022 02; 19(2):e1003910. Ryu WS, Hong KS, Jeong SW, Park JE, Kim BJ, Kim JT, Lee KB, Park TH, Park SS, Park JM, Kang K, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Lee SJ, Kim JG, Cha JK, Kim DH, Lee J, Han MK, Park MS, Choi KH, Lee J, Saver JL, Lo EH, Bae HJ, Kim DE. PMID: 35120123; PMCID: PMC8815976.
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Diffusion-Weighted Imaging-Alone Endovascular Thrombectomy Triage in Acute Stroke: Simulating Diffusion-Perfusion Mismatch Using Machine Learning. J Stroke. 2022 Jan; 24(1):148-151. Kim YC, Seo WK, Baek IY, Lee JE, Song HN, Chung JW, Kim CK, Oh K, Suh SI, Bang OY, Kim GM, Saver JL, Liebeskind DS. PMID: 35135068; PMCID: PMC8829488.
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Endovascular treatment with versus without tirofiban for stroke patients with large vessel occlusion: The multicenter, randomized, placebo-controlled, double-blind RESCUE BT study protocol. Int J Stroke. 2022 12; 17(10):1151-1155. Qiu Z, Li F, Sang H, Liu W, Huang W, Li H, Zhang M, Zhou P, Lei B, Zhou Z, Saver JL, Nogueira RG, Zi W, Yang Q. PMID: 35083951.
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Prolonged migraine aura resembling ischemic stroke following CoronaVac vaccination: an extended case series. J Headache Pain. 2022 Jan 21; 23(1):13. Suwanwela NC, Kijpaisalratana N, Tepmongkol S, Rattanawong W, Vorasayan P, Charnnarong C, Tantivattana J, Roongruang S, Ongphichetmetha T, Panjasriprakarn P, Chutinet A, Akarathanawat W, Saver JL. PMID: 35062869; PMCID: PMC8777408.
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Association Between Endovascular Therapy Time to Treatment and Outcomes in Patients With Basilar Artery Occlusion. Circulation. 2022 03 22; 145(12):896-905. Joundi RA, Sun JL, Xian Y, Alhanti B, Nogueira RG, Bhatt DL, Fonarow GC, Saver J, Schwamm LH, Smith EE. PMID: 35050693.
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Effect of evolocumab on acute arterial events across all vascular territories : results from the FOURIER trial. Eur Heart J. 2021 12 14; 42(47):4821-4829. Oyama K, Giugliano RP, Tang M, Bonaca MP, Saver JL, Murphy SA, Ruzza A, Keech AC, Sever PS, Sabatine MS, Bergmark BA. PMID: 34537830.
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Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke. JAMA. 2021 12 14; 326(22):2277-2286. Kent DM, Saver JL, Kasner SE, Nelson J, Carroll JD, Chatellier G, Derumeaux G, Furlan AJ, Herrmann HC, Jüni P, Kim JS, Koethe B, Lee PH, Lefebvre B, Mattle HP, Meier B, Reisman M, Smalling RW, Soendergaard L, Song JK, Mas JL, Thaler DE. PMID: 34905030; PMCID: PMC8672231.
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Trial of Mobile Stroke Units. Reply. N Engl J Med. 2021 12 09; 385(24):2302-2303. Yamal JM, Saver JL, Grotta JC. PMID: 34879459.
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Ischemic Stroke and Pulmonary Arteriovenous Malformations: A Review. Neurology. 2022 02 01; 98(5):188-198. Topiwala KK, Patel SD, Saver JL, Streib CD, Shovlin CL. PMID: 34880092; PMCID: PMC8826462.
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INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): study protocol for a randomized controlled trial. Trials. 2021 Dec 06; 22(1):885. Song L, Chen C, Chen X, Guo Y, Liu F, Lin Y, Billot L, Li Q, Liu H, Si L, Ouyang M, Arima H, Bath PM, Ford GA, Robinson T, Sandset EC, Saver JL, Sprigg N, van der Worp HB, Zhang C, Yang J, Li G, Anderson CS, INTERACT4 investigators. PMID: 34872617; PMCID: PMC8646007.
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Machine Learning Automated Detection of Large Vessel Occlusion From Mobile Stroke Unit Computed Tomography Angiography. Stroke. 2022 05; 53(5):1651-1656. Czap AL, Bahr-Hosseini M, Singh N, Yamal JM, Nour M, Parker S, Kim Y, Restrepo L, Abdelkhaleq R, Salazar-Marioni S, Phan K, Bowry R, Rajan SS, Grotta JC, Saver JL, Giancardo L, Sheth SA. PMID: 34865511; PMCID: PMC9038611.
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Thrombectomy With and Without Computed Tomography Perfusion Imaging in the Early Time Window: A Pooled Analysis of Patient-Level Data. Stroke. 2022 Apr; 53(4):1348-1353. Jadhav AP, Goyal M, Ospel J, Campbell BC, Majoie CBLM, Dippel DW, White P, Bracard S, Guillemin F, Davalos A, Hill MD, Demchuk AM, Brown S, Saver JL, Muir KW, Mitchell P, Desai SM, Jovin TG. PMID: 34844423.
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Achieving More Rapid Door-to-Needle Times and Improved Outcomes in Acute Ischemic Stroke in a Nationwide Quality Improvement Intervention. Stroke. 2022 04; 53(4):1328-1338. Xian Y, Xu H, Smith EE, Saver JL, Reeves MJ, Bhatt DL, Hernandez AF, Peterson ED, Schwamm LH, Fonarow GC. PMID: 34802250.
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Standardized Reporting of Workflow Metrics in Acute Ischemic Stroke Treatment: Why and How? Stroke Vasc Interv Neurol. 2021 Nov; 1(1):e000177. Goyal M, Saver JL, Ganesh A, McDonough RV, Roos YBWEM, Boulouis G, Kurz M, Psychogios MN, Holmin S, Majoie CBLM, Bourcier R, Chandra R, Yoshimura S, Yavagal D, Gory B, Taschner C, Buck B, Jadhav A, Hill MD, Ospel JM. PMID: 41584468; PMCID: PMC12512355.
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Collateral Circulation in Thrombectomy for Stroke After 6 to 24 Hours in the DAWN Trial. Stroke. 2022 03; 53(3):742-748. Liebeskind DS, Saber H, Xiang B, Jadhav AP, Jovin TG, Haussen DC, Budzik RF, Bonafe A, Bhuva P, Yavagal DR, Hanel RA, Ribo M, Cognard C, Sila C, Hassan AE, Smith WS, Saver JL, Nogueira RG, DAWN Investigators. PMID: 34727737.
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Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data. J Neurol Neurosurg Psychiatry. 2022 01; 93(1):6-13. Moullaali TJ, Wang X, Sandset EC, Woodhouse LJ, Law ZK, Arima H, Butcher KS, Chalmers J, Delcourt C, Edwards L, Gupta S, Jiang W, Koch S, Potter J, Qureshi AI, Robinson TG, Al-Shahi Salman R, Saver JL, Sprigg N, Wardlaw JM, Anderson CS, Bath PM, Blood Pressure in Acute Stroke (BASC) Investigators. PMID: 34732465; PMCID: PMC8685661.
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Predictors of unfavorable outcomes despite substantial reperfusion: Insights from Analysis of Revascularization in Ischemic Stroke With EmboTrap II Study. Interv Neuroradiol. 2022 Oct; 28(5):556-561. Siddiqui AH, Waqas M, Andersson T, Saver JL, Mattle HP, Bozorgchami H, Ribó M, Zaidat OO. PMID: 34719305; PMCID: PMC9511624.
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SWIFT DIRECT: Solitaire™ With the Intention For Thrombectomy Plus Intravenous t-PA Versus DIRECT Solitaire™ Stent-retriever Thrombectomy in Acute Anterior Circulation Stroke: Methodology of a randomized, controlled, multicentre study. Int J Stroke. 2022 07; 17(6):698-705. Fischer U, Kaesmacher J, S Plattner P, Bütikofer L, Mordasini P, Deppeler S, Cognard C, Pereira VM, Siddiqui AH, Froehler MT, Furlan AJ, Chapot R, Strbian D, Wiesmann M, Bressan J, Lerch S, Liebeskind DS, Saver JL, Gralla J, SWIFT DIRECT study investigators. PMID: 34569878.
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Heterogeneity between proximal and distal aspects of occlusive thrombi on pretreatment imaging in acute ischemic stroke. Neuroradiol J. 2022 Jun; 35(3):378-387. Hashimoto T, Kunieda T, Honda T, Scalzo F, Sharma LK, Hinman JD, Rao NM, Nour M, Bahr-Hosseini M, Saver JL, Raychev R, Liebeskind DS. PMID: 34609921; PMCID: PMC9244745.
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Endovascular Treatment for Acute Stroke Patients With a Pre-stroke Disability: An International Survey. Front Neurol. 2021; 12:714594. Salwi S, Niec JA, Hassan AE, Lindsell CJ, Khatri P, Mocco J, Saver JL, Mistry EA. PMID: 34671306; PMCID: PMC8520928.
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Prestroke Disability and Outcome After Thrombectomy for Emergent Anterior Circulation Large Vessel Occlusion Stroke. Neurology. 2021 11 09; 97(19):e1914-e1919. de Havenon A, Castonguay A, Nogueira R, Nguyen TN, English J, Satti SR, Veznedaroglu E, Saver JL, Mocco J, Khatri P, Mistry E, Zaidat OO. PMID: 34544817; PMCID: PMC8601211.
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Prospective, Multicenter, Controlled Trial of Mobile Stroke Units. N Engl J Med. 2021 09 09; 385(11):971-981. Grotta JC, Yamal JM, Parker SA, Rajan SS, Gonzales NR, Jones WJ, Alexandrov AW, Navi BB, Nour M, Spokoyny I, Mackey J, Persse D, Jacob AP, Wang M, Singh N, Alexandrov AV, Fink ME, Saver JL, English J, Barazangi N, Bratina PL, Gonzalez M, Schimpf BD, Ackerson K, Sherman C, Lerario M, Mir S, Im J, Willey JZ, Chiu D, Eisshofer M, Miller J, Ornelas D, Rhudy JP, Brown KM, Villareal BM, Gausche-Hill M, Bosson N, Gilbert G, Collins SQ, Silnes K, Volpi J, Misra V, McCarthy J, Flanagan T, Rao CPV, Kass JS, Griffin L, Rangel-Gutierrez N, Lechuga E, Stephenson J, Phan K, Sanders Y, Noser EA, Bowry R. PMID: 34496173.
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Thrombolysis in Mild Stroke: A Comparative Analysis of the PRISMS and MaRISS Studies. Stroke. 2021 10; 52(10):e586-e589. Asdaghi N, Romano JG, Gardener H, Campo-Bustillo I, Purdon B, Khan YM, Gulati D, Broderick JP, Schwamm LH, Smith EE, Saver JL, Sacco R, Khatri P. PMID: 34496619.
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Automated Final Lesion Segmentation in Posterior Circulation Acute Ischemic Stroke Using Deep Learning. Diagnostics (Basel). 2021 Sep 04; 11(9). Zoetmulder R, Konduri PR, Obdeijn IV, Gavves E, Išgum I, Majoie CBLM, Dippel DWJ, Roos YBWEM, Goyal M, Mitchell PJ, Campbell BCV, Lopes DK, Reimann G, Jovin TG, Saver JL, Muir KW, White P, Bracard S, Chen B, Brown S, Schonewille WJ, van der Hoeven E, Puetz V, Marquering HA. PMID: 34573963; PMCID: PMC8466415.
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Value of infarct location in the prediction of functional outcome in patients with an anterior large vessel occlusion: results from the HERMES study. Neuroradiology. 2022 Mar; 64(3):521-530. Tolhuisen ML, Ernst M, Boers AMM, Brown S, Beenen LFM, Guillemin F, Roos YBWEM, Saver JL, van Oostenbrugge R, Demchuck AM, van Zwam W, Jovin TG, Berkhemer OA, Muir KW, Bracard S, Campbell BCV, van der Lugt A, White P, Hill MD, Dippel DWJ, Mitchell PJ, Goyal M, Caan MWA, Marquering HA, Majoie CBLM, HERMES collaborators. PMID: 34476512; PMCID: PMC8850210.
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Frequency, Characteristics, and Outcomes of Endovascular Thrombectomy in Patients With Stroke Beyond 6 Hours of Onset in US Clinical Practice. Stroke. 2021 12; 52(12):3805-3814. Zachrison KS, Schwamm LH, Xu H, Matsouaka R, Shah S, Smith EE, Xian Y, Fonarow GC, Saver J. PMID: 34470490.
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Outcomes Among Patients With Reversible Cerebral Vasoconstriction Syndrome: A Nationwide United States Analysis. Stroke. 2021 12; 52(12):3970-3977. Patel SD, Topiwala K, Otite Oliver F, Saber H, Panza G, Mui G, Liebeskind DS, Saver JL, Alberts M, Ducros A. PMID: 34470494.
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Stent Retriever Thrombectomy for Anterior vs. Posterior Circulation Ischemic Stroke: Analysis of the STRATIS Registry. Front Neurol. 2021; 12:706130. Jahan R, Liebeskind DS, Zaidat OO, Mueller-Kronast NH, Froehler MT, Saver JL. PMID: 34504469; PMCID: PMC8421856.
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Cerebral Edema in Patients With Large Hemispheric Infarct Undergoing Reperfusion Treatment: A HERMES Meta-Analysis. Stroke. 2021 11; 52(11):3450-3458. Ng FC, Yassi N, Sharma G, Brown SB, Goyal M, Majoie CBLM, Jovin TG, Hill MD, Muir KW, Saver JL, Guillemin F, Demchuk AM, Menon BK, San Roman L, Liebeskind DS, White P, Dippel DWJ, Davalos A, Bracard S, Mitchell PJ, Wald MJ, Davis SM, Sheth KN, Kimberly WT, Campbell BCV, HERMES Collaborators. PMID: 34384229; PMCID: PMC8545835.
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Standardized Nomenclature for Modified Rankin Scale Global Disability Outcomes: Consensus Recommendations From Stroke Therapy Academic Industry Roundtable XI. Stroke. 2021 08; 52(9):3054-3062. Saver JL, Chaisinanunkul N, Campbell BCV, Grotta JC, Hill MD, Khatri P, Landen J, Lansberg MG, Venkatasubramanian C, Albers GW, XIth Stroke Treatment Academic Industry Roundtable. PMID: 34320814.
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Should Tenecteplase be Given in Clinical Practice for Acute Ischemic Stroke Thrombolysis? Stroke. 2021 08; 52(9):3075-3080. Putaala J, Saver JL, Nour M, Kleindorfer D, McDermott M, Kaste M. PMID: 34315253.
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Author Correction: Differential expression of circulating exosomal microRNAs in refractory intracranial atherosclerosis associated with antiangiogenesis. Sci Rep. 2021 Jul 21; 11(1):15266. Jiang H, Toscano JF, Song SS, Schlick KH, Dumitrascu OM, Pan J, Lyden PD, Saver JL, Gonzalez NR. PMID: 34290283; PMCID: PMC8295272.
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Endovascular Treatment Effect Diminishes With Increasing Thrombus Perviousness: Pooled Data From 7 Trials on Acute Ischemic Stroke. Stroke. 2021 11; 52(11):3633-3641. Kappelhof M, Tolhuisen ML, Treurniet KM, Dutra BG, Alves H, Zhang G, Brown S, Muir KW, Dávalos A, Roos YBWEM, Saver JL, Demchuk AM, Jovin TG, Bracard S, Campbell BCV, van der Lugt A, Guillemin F, White P, Hill MD, Dippel DWJ, Mitchell PJ, Goyal M, Marquering HA, Majoie CBLM, HERMES Collaborators. PMID: 34281377; PMCID: PMC8547583.
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Serial ASPECTS in the DAWN Trial: Infarct Evolution and Clinical Impact. Stroke. 2021 10; 52(10):3318-3324. Liebeskind DS, Saber H, Bhuva P, Xiang B, Yoo AJ, Jadhav AP, Haussen DC, Budzik RF, Bonafe A, Yavagal DR, Hanel RA, Ribo M, Cognard C, Sila C, Hassan AE, Smith WS, Saver JL, Nogueira RG, Jovin TG. PMID: 34281376.
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Intensive Medical Management to Prevent Large and Small Artery Atherothrombotic Stroke: Time to Expand the Horizon. JAMA. 2021 Jul 20; 326(3):217-218. Lee M, Ovbiagele B, Saver JL. PMID: 34196657.
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Prediction of Outcome and Endovascular Treatment Benefit: Validation and Update of the MR PREDICTS Decision Tool. Stroke. 2021 08; 52(9):2764-2772. Venema E, Roozenbeek B, Mulder MJHL, Brown S, Majoie CBLM, Steyerberg EW, Demchuk AM, Muir KW, Dávalos A, Mitchell PJ, Bracard S, Berkhemer OA, Lycklama À Nijeholt GJ, van Oostenbrugge RJ, Roos YBWEM, van Zwam WH, van der Lugt A, Hill MD, White P, Campbell BCV, Guillemin F, Saver JL, Jovin TG, Goyal M, Dippel DWJ, Lingsma HF, HERMES collaborators and MR CLEAN Registry Investigators*. PMID: 34266308; PMCID: PMC8378416.
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Endovascular thrombectomy without versus with intravenous thrombolysis in acute ischemic stroke: a non-inferiority meta-analysis of randomized clinical trials. J Neurointerv Surg. 2022 Mar; 14(3):227-232. Lin CH, Saver JL, Ovbiagele B, Huang WY, Lee M. PMID: 34266909; PMCID: PMC8862103.
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Acute Stroke Imaging Research Roadmap IV: Imaging Selection and Outcomes in Acute Stroke Clinical Trials and Practice. Stroke. 2021 08; 52(8):2723-2733. Campbell BCV, Lansberg MG, Broderick JP, Derdeyn CP, Khatri P, Sarraj A, Saver JL, Vagal A, Albers GW, STAIR XI Consortium. PMID: 34233464; PMCID: PMC8316368.
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PRIMED2 Preclinical Evidence Scoring Tool to Assess Readiness for Translation of Neuroprotection Therapies. Transl Stroke Res. 2022 04; 13(2):222-227. Bahr-Hosseini M, Bikson M, Iacoboni M, Liebeskind DS, Hinman JD, Carmichael ST, Saver JL. PMID: 34196953; PMCID: PMC8918446.
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Perspective on New Class of Radially Adjustable Stentrievers for Acute Ischemic Stroke: Insights from the Multicenter Tiger Trial. World Neurosurg. 2021 07; 151:291-292. Gupta R, Saver JL. PMID: 34243636.
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Lipid-Lowering Therapy and Hemorrhagic Stroke Risk: Comparative Meta-Analysis of Statins and PCSK9 Inhibitors. Stroke. 2021 10; 52(10):3142-3150. Sanz-Cuesta BE, Saver JL. PMID: 34154390.
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Hematoma Expansion Shift Analysis to Assess Acute Intracerebral Hemorrhage Treatments. Neurology. 2021 08 24; 97(8):e755-e764. Yogendrakumar V, Ramsay T, Menon BK, Qureshi AI, Saver JL, Dowlatshahi D. PMID: 34144995.
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Healthy Life-Year Costs of Treatment Speed From Arrival to Endovascular Thrombectomy in Patients With Ischemic Stroke: A Meta-analysis of Individual Patient Data From 7 Randomized Clinical Trials. JAMA Neurol. 2021 06 01; 78(6):709-717. Almekhlafi MA, Goyal M, Dippel DWJ, Majoie CBLM, Campbell BCV, Muir KW, Demchuk AM, Bracard S, Guillemin F, Jovin TG, Mitchell P, White P, Hill MD, Brown S, Saver JL, HERMES Trialists Collaboration. PMID: 33938914; PMCID: PMC8094030.
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Frequency, Determinants, and Outcomes of Emboli to Distal and New Territories Related to Mechanical Thrombectomy for Acute Ischemic Stroke. Stroke. 2021 07; 52(7):2241-2249. Wong GJ, Yoo B, Liebeskind D, Baharvahdat H, Gornbein J, Jahan R, Szeder V, Duckwiler G, Tateshima S, Colby G, Nour M, Sharma L, Rao N, Hinman J, Starkman S, Saver JL, UCLA Thrombectomy Investigators*. PMID: 34011171.
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Access to Mechanical Thrombectomy for Ischemic Stroke in the United States. Stroke. 2021 08; 52(8):2554-2561. Kamel H, Parikh NS, Chatterjee A, Kim LK, Saver JL, Schwamm LH, Zachrison KS, Nogueira RG, Adeoye O, Díaz I, Ryan AM, Pandya A, Navi BB. PMID: 33980045; PMCID: PMC8316281.
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Benchmarking the Extent and Speed of Reperfusion: First Pass TICI 2c-3 Is a Preferred Endovascular Reperfusion Endpoint. Front Neurol. 2021; 12:669934. Yoo AJ, Soomro J, Andersson T, Saver JL, Ribo M, Bozorgchami H, Dabus G, Liebeskind DS, Jadhav A, Mattle H, Zaidat OO. PMID: 34046008; PMCID: PMC8144635.
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Circadian Biology and Stroke. Stroke. 2021 06; 52(6):2180-2190. Lo EH, Albers GW, Dichgans M, Donnan G, Esposito E, Foster R, Howells DW, Huang YG, Ji X, Klerman EB, Lee S, Li W, Liebeskind DS, Lizasoain I, Mandeville ET, Moro MA, Ning M, Ray D, Sakadžic S, Saver JL, Scheer FAJL, Selim M, Tiedt S, Zhang F, Buchan AM. PMID: 33940951.
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Automatic Acute Stroke Symptom Detection and Emergency Medical Systems Alerting by Mobile Health Technologies: A Review. J Stroke Cerebrovasc Dis. 2021 Jul; 30(7):105826. Bat-Erdene BO, Saver JL. PMID: 33932749.
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Clinical effectiveness of endovascular stroke treatment in the early and extended time windows. Int J Stroke. 2022 04; 17(4):389-399. Nogueira RG, Haussen DC, Liebeskind DS, Jovin TG, Gupta R, Saver JL, Jadhav AP, Budzik RF, Baxter B, Krajina A, Bonafe A, Malek A, Narata AP, Mohammaden MH, Zhang Y, Morgan P, Ji M, Bartolini B, English J, Albers GW, Mlynash M, Lansberg MG, Frankel MR, Pereira VM, Veznedaroglu E, Trevo Registry, SWIFT Prime, DEFUSE 3 and DAWN Trial Investigators. PMID: 33705210.
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Intravenous tPA Delays Door-To-Puncture Time in Acute Ischemic Stroke with Large Vessel Occlusion. J Stroke Cerebrovasc Dis. 2021 Jun; 30(6):105732. Atchaneeyasakul K, Desai S, Malhotra K, Dolia J, Shah K, Saver JL, Jovin T, Jadhav AP. PMID: 33865227.
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New Class of Radially Adjustable Stentrievers for Acute Ischemic Stroke: Primary Results of the Multicenter TIGER Trial. Stroke. 2021 05; 52(5):1534-1544. Gupta R, Saver JL, Levy E, Zaidat OO, Yavagal D, Liebeskind DS, Khaldi A, Gross B, Lang M, Narayanan S, Jankowitz B, Snyder K, Siddiqui A, Davies J, Lin E, Hassan A, Hanel R, Aghaebrahim A, Kaushal R, Malek A, Mueller-Kronast N, Starke R, Bozorgchami H, Nesbit G, Horikawa M, Priest R, Liu J, Budzik RF, Pema P, Vora N, Taqi MA, Samaniego E, Wang QT, Nossek E, Dabus G, Linfante I, Puri A, Abergel E, Starkman S, Tateshima S, Jadhav AP, TIGER Trial Investigators. PMID: 33739136; PMCID: PMC8078128.
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Encephaloduroarteriosynangiosis Averts Stroke in Atherosclerotic Patients With Border-Zone Infarct: Post Hoc Analysis From a Performance Criterion Phase II Trial. Neurosurgery. 2021 03 15; 88(4):E312-E318. Quintero-Consuegra MD, Toscano JF, Babadjouni R, Nisson P, Kayyali MN, Chang D, Almallouhi E, Saver JL, Gonzalez NR. PMID: 33469657; PMCID: PMC7956046.
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Long-term cognitive and multimodal imaging outcomes after carotid artery stenting vs intensive medication alone for severe asymptomatic carotid stenosis. J Formos Med Assoc. 2022 Jan; 121(1 Pt 1):134-143. Lin CJ, Chang FC, Lin CJ, Liaw YC, Tu PC, Wang PN, Saver JL, Lee IH. PMID: 33674231.
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Association of Antiplatelet Therapy, Including Cilostazol, With Improved Survival in Patients With Moyamoya Disease in a Nationwide Study. J Am Heart Assoc. 2021 02; 10(5):e017701. Seo WK, Kim JY, Choi EH, Kim YS, Chung JW, Saver JL, Bang OY, Kim GM. PMID: 33615836; PMCID: PMC8174237.
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Intense Arm Rehabilitation Therapy Improves the Modified Rankin Scale Score: Association Between Gains in Impairment and Function. Neurology. 2021 04 06; 96(14):e1812-e1822. Cramer SC, Le V, Saver JL, Dodakian L, See J, Augsburger R, McKenzie A, Zhou RJ, Chiu NL, Heckhausen J, Cassidy JM, Scacchi W, Smith MT, Barrett AM, Knutson J, Edwards D, Putrino D, Agrawal K, Ngo K, Roth EJ, Tirschwell DL, Woodbury ML, Zafonte R, Zhao W, Spilker J, Wolf SL, Broderick JP, Janis S. PMID: 33589538; PMCID: PMC8105969.
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The Utility of Domain-Specific End Points in Acute Stroke Trials. Stroke. 2021 03; 52(3):1154-1161. Cramer SC, Wolf SL, Saver JL, Johnston KC, Mocco J, Lansberg MG, Savitz SI, Liebeskind DS, Smith W, Wintermark M, Elm JJ, Khatri P, Broderick JP, Janis S, NIH StrokeNet Recovery and Rehabilitation Group and the Acute Stroke Group*. PMID: 33563009; PMCID: PMC7902441.
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Health Economic Impact of First Pass Success: An Asia-Pacific Cost Analysis of the ARISE II Study. J Stroke. 2021 Jan; 23(1):139-143. Yeo L, Zaidat OO, Saver JL, Mattle HP, Lee SHY, Kottenmeier E, Cameron HL, Qadeer RA, Andersson T. PMID: 33600713; PMCID: PMC7900400.
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Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke. JAMA. 2021 01 19; 325(3):229-231. Saver JL, Adeoye O. PMID: 33464293.
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Role of Intravenous Tissue Plasminogen Activator in Acute Ischemic Stroke with Large Vessel Occlusion. World Neurosurg. 2021 04; 148:e321-e325. Ooi YC, Miremadi BB, Mukarram F, Kaneko N, Nour M, Colby G, Jahan R, Tateshima S, Duckwiler G, Saver J, Szeder V. PMID: 33444835.
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Platelet-Derived Growth Factor Is Associated with Progression of Symptomatic Intracranial Atherosclerotic Stenosis. J Clin Neurol. 2021 Jan; 17(1):70-76. Kim KJ, Jeong SW, Ryu WS, Kim DE, Saver JL, Kim JS, Kwon SU, TOSS-2 Study Group. PMID: 33480201; PMCID: PMC7840326.
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Health economic impact of first-pass success among patients with acute ischemic stroke treated with mechanical thrombectomy: a United States and European perspective. J Neurointerv Surg. 2021 Dec; 13(12):1117-1123. Zaidat OO, Ribo M, Mattle HP, Saver JL, Bozorgchami H, Yoo AJ, Ehm A, Kottenmeier E, Cameron HL, Qadeer RA, Andersson T. PMID: 33443119; PMCID: PMC8606461.
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Impact of eloquent motor cortex-tissue reperfusion beyond the traditional thrombolysis in cerebral infarction (TICI) scoring after thrombectomy. J Neurointerv Surg. 2021 Nov; 13(11):990-994. Raychev R, Saber H, Saver JL, Hinman JD, Brown S, Vinuela F, Duckwiler G, Jahan R, Tateshima S, Szeder V, Nour M, Colby GP, Restrepo L, Kim D, Bahr-Hosseini M, Ali L, Starkman S, Rao N, Nogueira RG, Liebeskind D. PMID: 33443113; PMCID: PMC8526878.
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Target: Stroke Was Associated With Faster Intravenous Thrombolysis and Improved One-Year Outcomes for Acute Ischemic Stroke in Medicare Beneficiaries. Circ Cardiovasc Qual Outcomes. 2020 12; 13(12):e007150. Man S, Xian Y, Holmes DN, Matsouaka RA, Saver JL, Smith EE, Bhatt DL, Schwamm LH, Fonarow GC. PMID: 33302714.
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Computed Tomography Perfusion-Based Machine Learning Model Better Predicts Follow-Up Infarction in Patients With Acute Ischemic Stroke. Stroke. 2021 01; 52(1):223-231. Kuang H, Qiu W, Boers AM, Brown S, Muir K, Majoie CBLM, Dippel DWJ, White P, Epstein J, Mitchell PJ, Dávalos A, Bracard S, Campbell B, Saver JL, Jovin TG, Rubiera M, Khaw AV, Shankar JJ, Fainardi E, Hill MD, Demchuk AM, Goyal M, Menon BK. PMID: 33280549.
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Adiposity and Outcome After Ischemic Stroke: Obesity Paradox for Mortality and Obesity Parabola for Favorable Functional Outcomes. Stroke. 2021 01; 52(1):144-151. Liu Z, Sanossian N, Starkman S, Avila-Rinek G, Eckstein M, Sharma LK, Liebeskind D, Conwit R, Hamilton S, Saver JL, FAST-MAG Investigators and Coordinators. PMID: 33272129.
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Benefit of endovascular thrombectomy for M2 middle cerebral artery occlusion in the ARISE II study. J Neurointerv Surg. 2021 Sep; 13(9):779-783. de Havenon A, Narata AP, Amelot A, Saver JL, Bozorgchami H, Mattle HP, Ribo M, Andersson T, Zaidat OO, ARISE II investigators. PMID: 33219148; PMCID: PMC8134506.
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Selective Brain Hypothermia in Acute Ischemic Stroke: Reperfusion Without Reperfusion Injury. Front Neurol. 2020; 11:594289. Choi JH, Poli S, Chen M, Nguyen TN, Saver JL, Matouk C, Pile-Spellman J. PMID: 33281733; PMCID: PMC7691595.
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Encephaloduroarteriosynangiosis (EDAS) revascularization for symptomatic intracranial atherosclerotic steno-occlusive (ERSIAS) Phase-II objective performance criterion trial. Int J Stroke. 2021 08; 16(6):701-709. Gonzalez NR, Jiang H, Lyden P, Song S, Schlick K, Dumitrascu O, Quintero-Consuegra MD, Toscano JF, Liebeskind DS, Restrepo L, Rao N, Hinman J, Alexander MJ, Schievink W, Piantadosi S, Saver JL. PMID: 33115382.
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The Minimal Clinically Important Difference for Achievement of Substantial Reperfusion With Endovascular Thrombectomy Devices in Acute Ischemic Stroke Treatment. Front Neurol. 2020; 11:524220. Lin CJ, Saver JL. PMID: 33123069; PMCID: PMC7569750.
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Stroke Thrombolysis With Tenecteplase to Reduce Emergency Department Spread of Coronavirus Disease 2019 and Shortages of Alteplase. JAMA Neurol. 2020 10 01; 77(10):1203-1204. Warach SJ, Saver JL. PMID: 32687579.
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Decision-Making Visual Aids for Late, Imaging-Guided Endovascular Thrombectomy for Acute Ischemic Stroke. J Stroke. 2020 Sep; 22(3):377-386. Moshayedi P, Liebeskind DS, Jadhav A, Jahan R, Lansberg M, Sharma L, Nogueira RG, Saver JL. PMID: 33053953; PMCID: PMC7568977.
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Efficient Multimodal MRI Evaluation for Endovascular Thrombectomy of Anterior Circulation Large Vessel Occlusion. J Stroke Cerebrovasc Dis. 2020 Dec; 29(12):105271. Atchaneeyasakul K, Liebeskind DS, Jahan R, Starkman S, Sharma L, Yoo B, Avelar J, Rao N, Hinman J, Duckwiler G, Nour M, Szeder V, Tateshima S, Colby G, Hosseini MB, Raychev R, Kim D, Saver JL, UCLA Reperfusion Therapy Investigators. PMID: 32992192.
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The Effect of Early Treatment with Intravenous Magnesium Sulfate on the Incidence of Cardiac Comorbidities in Hospitalized Stroke Patients. Cardiovasc Ther. 2020; 2020:1494506. Bechler K, Shkirkova K, Saver JL, Starkman S, Hamilton S, Liebeskind DS, Eckstein M, Stratton S, Pratt F, Conwit R, Sanossian N. PMID: 33072188; PMCID: PMC7533752.
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Public health and cost consequences of time delays to thrombectomy for acute ischemic stroke. Neurology. 2020 11 03; 95(18):e2465-e2475. Kunz WG, Hunink MG, Almekhlafi MA, Menon BK, Saver JL, Dippel DWJ, Majoie CBLM, Jovin TG, Davalos A, Bracard S, Guillemin F, Campbell BCV, Mitchell PJ, White P, Muir KW, Brown S, Demchuk AM, Hill MD, Goyal M, HERMES Collaborators. PMID: 32943483.
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Challenging the Ischemic Core Concept in Acute Ischemic Stroke Imaging. Stroke. 2020 10; 51(10):3147-3155. Goyal M, Ospel JM, Menon B, Almekhlafi M, Jayaraman M, Fiehler J, Psychogios M, Chapot R, van der Lugt A, Liu J, Yang P, Agid R, Hacke W, Walker M, Fischer U, Asdaghi N, McTaggart R, Srivastava P, Nogueira RG, Moret J, Saver JL, Hill MD, Dippel D, Fisher M. PMID: 32933417.
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Patterns of Mechanical Thrombectomy for Stroke Before and After the 2015 Pivotal Trials and US National Guideline Update. J Stroke Cerebrovasc Dis. 2020 Dec; 29(12):105292. Atchaneeyasakul K, Liaw N, Lee RH, Liebeskind DS, Saver JL. PMID: 32992172.
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Effect of age and baseline ASPECTS on outcomes in large-vessel occlusion stroke: results from the HERMES collaboration. J Neurointerv Surg. 2021 Sep; 13(9):790-793. Ospel JM, Kappelhof M, Kashani N, Menon BK, Campbell BCV, San Roman L, Demchuk AM, Dippel DWJ, Saver JL, Jovin TG, Mitchell P, Bracard S, Muir K, White P, Guillemin F, Majoie CBLM, Hill MD, Brown S, Goyal M, HERMES collaborators. PMID: 32929047.
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Risk of Paradoxical Embolism (RoPE)-Estimated Attributable Fraction Correlates With the Benefit of Patent Foramen Ovale Closure: An Analysis of 3 Trials. Stroke. 2020 10; 51(10):3119-3123. Kent DM, Saver JL, Ruthazer R, Furlan AJ, Reisman M, Carroll JD, Smalling RW, Jüni P, Mattle HP, Meier B, Thaler DE. PMID: 32921262; PMCID: PMC7831886.
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Major bleeding risk with non-vitamin K antagonist oral anticoagulant vs. aspirin in heart failure: network meta-analysis. ESC Heart Fail. 2020 Dec; 7(6):3962-3970. Huang WY, Saver JL, Wu YL, Lin CJ, Lee M, Ovbiagele B. PMID: 32924283; PMCID: PMC7754774.
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A Prehospital Acute Stroke Trial has Only Modest Impact on Enrollment in Concurrent, Post-arrival-Recruiting Stroke Trials. J Stroke Cerebrovasc Dis. 2020 Nov; 29(11):105200. Johnson-Black P, Wong G, Starkman S, Sanossian N, Sharma L, Kim-Tenser M, Liebeskind D, Restrepo-Jimenez L, Valdes-Sueiras M, Stratton S, Eckstein M, Pratt F, Conwit R, Hamilton S, Guzy J, Grunberg I, Shkirkova K, Hemphill C, Saver J, FAST-MAG Investigators and Coordinators. PMID: 33066919; PMCID: PMC7573197.
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Thrombectomy for Distal, Medium Vessel Occlusions: A Consensus Statement on Present Knowledge and Promising Directions. Stroke. 2020 09; 51(9):2872-2884. Saver JL, Chapot R, Agid R, Hassan A, Jadhav AP, Liebeskind DS, Lobotesis K, Meila D, Meyer L, Raphaeli G, Gupta R, Distal Thrombectomy Summit Group*†. PMID: 32757757.
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Predictors and Functional Outcomes of Fast, Intermediate, and Slow Progression Among Patients With Acute Ischemic Stroke. Stroke. 2020 08; 51(8):2553-2557. Seo WK, Liebeskind DS, Yoo B, Sharma L, Jahan R, Duckwiler G, Tateshima S, Nour M, Szeder V, Colby G, Starkman S, Rao N, Bahr Hosseini M, Saver JL, UCLA Penumbra Imaging Investigators. PMID: 32611286.
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Proposal for Updated Nomenclature and Classification of Potential Causative Mechanism in Patent Foramen Ovale-Associated Stroke. JAMA Neurol. 2020 07 01; 77(7):878-886. Elgendy AY, Saver JL, Amin Z, Boudoulas KD, Carroll JD, Elgendy IY, Grunwald IQ, Gertz ZM, Hijazi ZM, Horlick EM, Kasner SE, Kent DM, Kumar P, Kavinsky CJ, Liebeskind DS, Lutsep H, Mojadidi MK, Messé SR, Mas JL, Mattle HP, Meier B, Mahmoud A, Mahmoud AN, Nietlispach F, Patel NK, Rhodes JF, Reisman M, Sommer RJ, Sievert H, Søndergaard L, Zaman MO, Thaler D, Tobis JM. PMID: 32282016.
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Reperfusion Into Severely Damaged Brain Tissue Is Associated With Occurrence of Parenchymal Hemorrhage for Acute Ischemic Stroke. Front Neurol. 2020; 11:586. Yu S, Ma SJ, Liebeskind DS, Qiao XJ, Yan L, Saver JL, Salamon N, Wang DJJ. PMID: 32670187; PMCID: PMC7332705.
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National Institutes of Health StrokeNet During the Time of COVID-19 and Beyond. Stroke. 2020 08; 51(8):2580-2586. Broderick JP, Elm JJ, Janis LS, Zhao W, Moy CS, Dillon CR, Chimowitz MI, Sacco RL, Cramer SC, Wolf SL, Johnston KC, Saver JL, Marshall RS, Brown D, Wintermark M, Elkind MSV, Kamel H, Tirschwell DL, Longstreth WT, Chervin RD, Adeoye OM, Barreto AD, Grotta JC, Ramey SL, Lo WD, Feng W, Schlaug G, Sheth KN, Selim M, Naidech AM, Lansberg MG, Lazar RM, Albers GW, Griffin JS, Sirline LP, Frasure J, Wright CB, Khatri P, NIH StrokeNet Investigators. PMID: 32716819; PMCID: PMC7326322.
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Thrombectomy for Stroke in the Public Health Care System of Brazil. N Engl J Med. 2020 06 11; 382(24):2316-2326. Martins SO, Mont'Alverne F, Rebello LC, Abud DG, Silva GS, Lima FO, Parente BSM, Nakiri GS, Faria MB, Frudit ME, de Carvalho JJF, Waihrich E, Fiorot JA, Cardoso FB, Hidalgo RCT, Zétola VF, Carvalho FM, de Souza AC, Dias FA, Bandeira D, Miranda Alves M, Wagner MB, Carbonera LA, Oliveira-Filho J, Bezerra DC, Liebeskind DS, Broderick J, Molina CA, Fogolin Passos JE, Saver JL, Pontes-Neto OM, Nogueira RG, RESILIENT Investigators. PMID: 32521133.
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Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients With Acute Ischemic Stroke. JAMA. 2020 06 02; 323(21):2170-2184. Man S, Xian Y, Holmes DN, Matsouaka RA, Saver JL, Smith EE, Bhatt DL, Schwamm LH, Fonarow GC. PMID: 32484532; PMCID: PMC7267850.
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Impact of EMS bypass to endovascular capable hospitals: geospatial modeling analysis of the US STRATIS registry. J Neurointerv Surg. 2020 Nov; 12(11):1058-1063. Mueller-Kronast N, Froehler MT, Jahan R, Zaidat O, Liebeskind D, Saver JL, STRATIS Investigators. PMID: 32385089; PMCID: PMC7569363.
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Call to Action: SARS-CoV-2 and CerebrovAscular DisordErs (CASCADE). J Stroke Cerebrovasc Dis. 2020 09; 29(9):104938. Abootalebi S, Aertker BM, Andalibi MS, Asdaghi N, Aykac O, Azarpazhooh MR, Bahit MC, Barlinn K, Basri H, Shahripour RB, Bersano A, Biller J, Borhani-Haghighi A, Brown RD, Campbell BC, Cruz-Flores S, De Silva DA, Di Napoli M, Divani AA, Edgell RC, Fifi JT, Ghoreishi A, Hirano T, Hong KS, Hsu CY, Huang JF, Inoue M, Jagolino AL, Kapral M, Kee HF, Keser Z, Khatri R, Koga M, Krupinski J, Liebeskind DS, Liu L, Ma H, Maud A, McCullough LD, Meyer DM, Mifsud V, Morovatdar N, Nilanont Y, Oxley TJ, Özdemir AÖ, Pandian J, Pantoni L, Papamitsakis NIH, Parry-Jones A, Phan T, Rodriguez G, Romano JG, Sabaa-Ayoun Z, Saber H, Sasannezhad P, Saver JL, Scharf E, Shuaib A, Silver B, Singhal S, Smith CJ, Stranges S, Sylaja PN, Torbey M, Toyoda K, Tsivgoulis G, Wasay M, Yassi N, Yoshimoto T, Zamani B, Zand R. PMID: 32807412; PMCID: PMC7205703.
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Distributional Validity and Prognostic Power of the National Institutes of Health Stroke Scale in US Administrative Claims Data. JAMA Neurol. 2020 05 01; 77(5):606-612. Saber H, Saver JL. PMID: 32065612; PMCID: PMC7042858.
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Mechanisms of action of acute and subacute sphenopalatine ganglion stimulation for ischemic stroke. Int J Stroke. 2020 10; 15(8):839-848. Bahr-Hosseini M, Saver JL. PMID: 32326842.
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Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis. Stroke. 2020 05; 51(5):1546-1554. Giugliano RP, Pedersen TR, Saver JL, Sever PS, Keech AC, Bohula EA, Murphy SA, Wasserman SM, Honarpour N, Wang H, Lira Pineda A, Sabatine MS, FOURIER Investigators. PMID: 32312223.
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Acute insular infarction: Early outcomes of minor stroke with proximal artery occlusion. PLoS One. 2020; 15(3):e0229836. Min SH, Kim JT, Kang KW, Choi MJ, Yoon H, Shinohara Y, Lev MH, Saver JL, Cho KH. PMID: 32160209; PMCID: PMC7065779.
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Redefined Measure of Early Neurological Improvement Shows Treatment Benefit of Alteplase Over Placebo. Stroke. 2020 04; 51(4):1226-1230. Agarwal S, Scher E, Lord A, Frontera J, Ishida K, Torres J, Rostanski S, Mistry E, Mac Grory B, Cutting S, Burton T, Silver B, Liberman AL, Lerario MP, Furie K, Grotta J, Khatri P, Saver J, Yaghi S. PMID: 32102629; PMCID: PMC7101071.
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Increased Access to and Use of Endovascular Therapy Following Implementation of a 2-Tiered Regional Stroke System. Stroke. 2020 03; 51(3):908-913. Bosson N, Gausche-Hill M, Saver JL, Sanossian N, Tadeo R, Clare C, Perez L, Williams M, Rasnake S, Nguyen PL, Los Angeles County Stroke Data Collaborative. PMID: 31987015.
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Improving economic evaluations in stroke: A report from the ESO Health Economics Working Group. Eur Stroke J. 2020 Jun; 5(2):184-192. Cadilhac DA, Kim J, Wilson A, Berge E, Patel A, Ali M, Saver J, Christensen H, Cuche M, Crews S, Wu O, Provoyeur M, McMeekin P, Durand-Zaleski I, Ford GA, Muhlemann N, Bath PM, Abdul-Rahim AH, Sunnerhagen K, Meretoja A, Thijs V, Weimar C, Massaro A, Ranta A, Lees KR, ESO Health Economics Working group. PMID: 32637652; PMCID: PMC7313366.
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Quality of Acute Stroke Care at Primary Stroke Centers Before and After Certification in Comparison to Never-Certified Hospitals. Front Neurol. 2019; 10:1396. Shkirkova K, Wang TT, Vartanyan L, Liebeskind DS, Eckstein M, Starkman S, Stratton S, Pratt FD, Hamilton S, Kim-Tenser M, Conwit R, Saver JL, Sanossian N. PMID: 32038463; PMCID: PMC6987385.
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Public Health and Cost Benefits of Successful Reperfusion After Thrombectomy for Stroke. Stroke. 2020 03; 51(3):899-907. Kunz WG, Almekhlafi MA, Menon BK, Saver JL, Hunink MG, Dippel DWJ, Majoie CBLM, Liebeskind DS, Jovin TG, Davalos A, Bracard S, Guillemin F, Campbell BCV, Mitchell PJ, White P, Muir KW, Brown S, Demchuk AM, Hill MD, Goyal M, HERMES Collaborators. PMID: 31964289.
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Paramedic Global Impression of Change During Prehospital Evaluation and Transport for Acute Stroke. Stroke. 2020 03; 51(3):784-791. Shkirkova K, Schuberg S, Balouzian E, Starkman S, Eckstein M, Stratton S, Pratt FD, Hamilton S, Sharma L, Liebeskind DS, Conwit R, Saver JL, Sanossian N, FAST-MAG Investigators and Coordinators. PMID: 31955642; PMCID: PMC7091257.
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Best Practices in Assessing Aging Physicians for Professional Competency. JAMA. 2020 01 14; 323(2):127-129. Saver JL. PMID: 31935011.
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Deep Learning Detection of Penumbral Tissue on Arterial Spin Labeling in Stroke. Stroke. 2020 02; 51(2):489-497. Wang K, Shou Q, Ma SJ, Liebeskind D, Qiao XJ, Saver J, Salamon N, Kim H, Yu Y, Xie Y, Zaharchuk G, Scalzo F, Wang DJJ. PMID: 31884904; PMCID: PMC7224203.
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Automatic segmentation of cerebral infarcts in follow-up computed tomography images with convolutional neural networks. J Neurointerv Surg. 2020 Sep; 12(9):848-852. Sales Barros R, Tolhuisen ML, Boers AM, Jansen I, Ponomareva E, Dippel DWJ, van der Lugt A, van Oostenbrugge RJ, van Zwam WH, Berkhemer OA, Goyal M, Demchuk AM, Menon BK, Mitchell P, Hill MD, Jovin TG, Davalos A, Campbell BCV, Saver JL, Roos YBWEM, Muir KW, White P, Bracard S, Guillemin F, Olabarriaga SD, Majoie CBLM, Marquering HA. PMID: 31871069; PMCID: PMC7476369.
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Differential expression of circulating exosomal microRNAs in refractory intracranial atherosclerosis associated with antiangiogenesis. Sci Rep. 2019 12 19; 9(1):19429. Jiang H, Toscano JF, Song SS, Schlick KH, Dumitrascu OM, Pan J, Lyden PD, Saver JL, Gonzalez NR. PMID: 31857618; PMCID: PMC6923371.
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Randomization of endovascular treatment with stent-retriever and/or thromboaspiration versus best medical therapy in acute ischemic stroke due to large vessel occlusion trial: Rationale and design. Int J Stroke. 2021 01; 16(1):100-109. Nogueira RG, Lima FO, Pontes-Neto OM, S Silva G, José Mont'Alverne F, Abud DG, Frudit M, Passos P, Haussen DC, Dabus G, de Freitas GR, Oliveira-Filho J, Bezerra DC, Liebeskind DS, Wagner MB, Passos JE, Molina CA, Broderick J, Saver JL, Martins SO. PMID: 31793395.
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Impact of Periprocedural and Technical Factors and Patient Characteristics on Revascularization and Outcome in the DAWN Trial. Stroke. 2020 01; 51(1):247-253. Tekle WG, Hassan AE, Jadhav AP, Haussen DC, Budzik RF, Bonafe A, Bhuva P, Yavagal DR, Hanel RA, Ribo M, Cognard C, Sila CA, Smith WS, Saver JL, Liebeskind DS, Shields R, Nogueira RG, Jovin TG, DAWN Trial Investigators. PMID: 31744425.
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Refined Sphenopalatine Ganglion Stimulator Placement and Intensity Setting to Augment Blood Flow and Neurologic Function. Stroke. 2019 12; 50(12):3512-3518. Saver JL, Kharaishvili N, Janelidze T, Beridze M, Zarqua N, Solberg Y, Bornstein NM, IMPACT-24M Trial Investigators. PMID: 31739771; PMCID: PMC7597988.
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Is Door-to-Needle Time Reduced for Emergency Medical Services Transported Stroke Patients Routed Directly to the Computed Tomography Scanner on Emergency Department Arrival? J Stroke Cerebrovasc Dis. 2020 Jan; 29(1):104477. Sloane B, Bosson N, Sanossian N, Saver JL, Perez L, Gausche-Hill M. PMID: 31699573.
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Noninferiority Margins in Trials of Thrombectomy Devices for Acute Ischemic Stroke: Is the Bar Being Set Too Low? Stroke. 2019 12; 50(12):3519-3526. Lin CJ, Saver JL. PMID: 31619155.
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Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage: Data From the RIGHT-2 Trial. Stroke. 2019 11; 50(11):3064-3071. Bath PM, Woodhouse LJ, Krishnan K, Appleton JP, Anderson CS, Berge E, Cala L, Dixon M, England TJ, Godolphin PJ, Hepburn T, Mair G, Montgomery AA, Phillips SJ, Potter J, Price CI, Randall M, Robinson TG, Roffe C, Rothwell PM, Sandset EC, Sanossian N, Saver JL, Siriwardena AN, Venables G, Wardlaw JM, Sprigg N. PMID: 31587658; PMCID: PMC6824503.
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Benefit of Endovascular Thrombectomy by Mode of Onset: Secondary Analysis of the DAWN Trial. Stroke. 2019 11; 50(11):3141-3146. Jadhav AP, Aghaebrahim A, Jankowitz BT, Haussen DC, Budzik RF, Bonafe A, Bhuva P, Yavagal DR, Hanel RA, Hassan AE, Ribo M, Cognard C, Sila CA, Zhang Y, Smith WS, Saver JL, Liebeskind DS, Nogueira RG, Jovin TG. PMID: 31570085.
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Central Nervous System Electrical Stimulation for Neuroprotection in Acute Cerebral Ischemia: Meta-Analysis of Preclinical Studies. Stroke. 2019 10; 50(10):2892-2901. Bahr Hosseini M, Hou J, Bikson M, Iacoboni M, Gornbein J, Saver JL. PMID: 31480966; PMCID: PMC6756951.
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Confirmatory Study of Time-Dependent Computed Tomographic Perfusion Thresholds for Use in Acute Ischemic Stroke. Stroke. 2019 11; 50(11):3269-3273. Qiu W, Kuang H, Lee TY, Boers AM, Brown S, Muir K, Majoie CBLM, Dippel DWJ, White P, Guillemin F, Mitchell PJ, Dávalos A, Bracard S, Campbell B, Saver JL, Jovin TG, Hill MD, Demchuk AM, Goyal M, Menon BK. PMID: 31480968.
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Does Sex Modify the Effect of Endovascular Treatment for Ischemic Stroke? Stroke. 2019 09; 50(9):2413-2419. Chalos V, de Ridder IR, Lingsma HF, Brown S, van Oostenbrugge RJ, Goyal M, Campbell BCV, Muir KW, Guillemin F, Bracard S, White P, Dávalos A, Jovin TG, Hill MD, Mitchell PJ, Demchuk AM, Saver JL, van Zwam WH, Dippel DWJ, HERMES Collaborators. PMID: 31412753; PMCID: PMC6727933.
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Sex Differences in Outcome After Endovascular Stroke Therapy for Acute Ischemic Stroke. Stroke. 2019 09; 50(9):2420-2427. Sheth SA, Lee S, Warach SJ, Gralla J, Jahan R, Goyal M, Nogueira RG, Zaidat OO, Pereira VM, Siddiqui A, Lutsep H, Liebeskind DS, McCullough LD, Saver JL. PMID: 31412752; PMCID: PMC6710145.
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Physiologic predictors of collateral circulation and infarct growth during anesthesia - Detailed analyses of the GOLIATH trial. J Cereb Blood Flow Metab. 2020 06; 40(6):1203-1212. Raychev R, Liebeskind DS, Yoo AJ, Rasmussen M, Arnaudov D, Brown S, Saver J, Simonsen CZ. PMID: 31366300; PMCID: PMC7238375.
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Frequency of Intracranial Hemorrhage With Low-Dose Aspirin in Individuals Without Symptomatic Cardiovascular Disease: A Systematic Review and Meta-analysis. JAMA Neurol. 2019 Aug 01; 76(8):906-914. Huang WY, Saver JL, Wu YL, Lin CJ, Lee M, Ovbiagele B. PMID: 31081871; PMCID: PMC6515567.
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Noncontrast Computed Tomography Alberta Stroke Program Early CT Score May Modify Intra-Arterial Treatment Effect in DAWN. Stroke. 2019 09; 50(9):2404-2412. Bhuva P, Yoo AJ, Jadhav AP, Jovin TG, Haussen DC, Bonafe A, Budzik RJ, Yavagal DR, Hanel RA, Hassan AE, Ribo M, Cognard C, Sila CA, Morgan PM, Zhang Y, Shields R, Smith W, Saver JL, Liebeskind DS, Nogueira RG, DAWN Trial Investigators. PMID: 31345135.
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Subject Retention in Prehospital Stroke Research Using a Telephone-Based Physician-Investigator Driven Enrollment Method. Cerebrovasc Dis Extra. 2019; 9(2):72-76. Rosell BJ, Shkirkova K, Saver JL, Liebeskind DS, Starkman S, Kim-Tenser M, Eckstein M, Sharma L, Conwit R, Hamilton S, Sanossian N. PMID: 31344699; PMCID: PMC6738216.
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Evidence that Tenecteplase Is Noninferior to Alteplase for Acute Ischemic Stroke: Meta-Analysis of 5 Randomized Trials. Stroke. 2019 08; 50(8):2156-2162. Burgos AM, Saver JL. PMID: 31318627.
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Magnitude of Benefit of Combined Endovascular Thrombectomy and Intravenous Fibrinolysis in Large Vessel Occlusion Ischemic Stroke. Stroke. 2019 09; 50(9):2433-2440. Young-Saver DF, Gornbein J, Starkman S, Saver JL. PMID: 31311465.
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Association Between Time to Treatment With Endovascular Reperfusion Therapy and Outcomes in Patients With Acute Ischemic Stroke Treated in Clinical Practice. JAMA. 2019 07 16; 322(3):252-263. Jahan R, Saver JL, Schwamm LH, Fonarow GC, Liang L, Matsouaka RA, Xian Y, Holmes DN, Peterson ED, Yavagal D, Smith EE. PMID: 31310296; PMCID: PMC6635908.
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Outcome in Direct Versus Transfer Patients in the DAWN Controlled Trial. Stroke. 2019 08; 50(8):2163-2167. Aghaebrahim A, Jadhav AP, Hanel R, Sauvageau E, Granja MF, Zhang Y, Haussen DC, Budzik RF, Bonafe A, Bhuva P, Ribo M, Cognard C, Sila C, Yavagal D, Hassan AE, Smith WS, Saver J, Liebeskind DS, Nogueira RG, Jovin TG, DAWN Investigators. PMID: 31303153.
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Oral short-acting antihypertensive medications and the occurrence of stroke: a nationwide case-crossover study. Hypertens Res. 2019 11; 42(11):1794-1800. Hsu CY, Huang LY, Saver JL, Wu YL, Lee JD, Chen PC, Lee M, Ovbiagele B. PMID: 31300722.
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Use of Wearable Technology in Remote Evaluation of Acute Stroke Patients: Feasibility and Reliability of a Google Glass-Based Device. J Stroke Cerebrovasc Dis. 2019 Oct; 28(10):104258. Noorian AR, Bahr Hosseini M, Avila G, Gerardi R, Andrle AF, Su M, Starkman S, Saver JL, Sharma LK. PMID: 31296476.
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Stroke Laterality Did Not Modify Outcomes in the HERMES Meta-Analysis of Individual Patient Data of 7 Trials. Stroke. 2019 08; 50(8):2118-2124. Almekhlafi MA, Hill MD, Roos YM, Campbell BCV, Muir KW, Demchuk AM, Bracard S, Gomis M, Guillemin F, Jovin TG, Menon BK, Mitchell P, White P, van der Lugt A, Saver J, Brown S, Goyal M. PMID: 31272328.
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Onset to reperfusion time as a determinant of outcomes across a wide range of ASPECTS in endovascular thrombectomy: pooled analysis of the SWIFT, SWIFT PRIME, and STAR studies. J Neurointerv Surg. 2020 Mar; 12(3):240-245. Kim JT, Goyal M, Levy EI, Liebeskind D, Jahan R, Pereira VM, Gralla J, Bonafe A, Saver JL. PMID: 31266857.
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Low fasting glucose and future risks of major adverse outcomes in people without baseline diabetes or cardiovascular disease: a systematic review and meta-analysis. BMJ Open. 2019 07 01; 9(7):e026010. Liao HW, Saver J, Yeh HC, Chen CS, Wu YL, Lee M, Ovbiagele B. PMID: 31266835; PMCID: PMC6609056.
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The impact of general anesthesia, baseline ASPECTS, time to treatment, and IV tPA on intracranial hemorrhage after neurothrombectomy: pooled analysis of the SWIFT PRIME, SWIFT, and STAR trials. J Neurointerv Surg. 2020 Jan; 12(1):2-6. Raychev R, Saver JL, Jahan R, Nogueira RG, Goyal M, Pereira VM, Gralla J, Levy EI, Yavagal DR, Cognard C, Liebeskind DS. PMID: 31239326.
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Blood Pressure Variability Predicts Poor In-Hospital Outcome in Spontaneous Intracerebral Hemorrhage. Stroke. 2019 08; 50(8):2023-2029. Divani AA, Liu X, Di Napoli M, Lattanzi S, Ziai W, James ML, Jafarli A, Jafari M, Saver JL, Hemphill JC, Vespa PM, Mayer SA, Petersen A. PMID: 31216966.
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An injectable implant to stimulate the sphenopalatine ganglion for treatment of acute ischaemic stroke up to 24 h from onset (ImpACT-24B): an international, randomised, double-blind, sham-controlled, pivotal trial. Lancet. 2019 07 20; 394(10194):219-229. Bornstein NM, Saver JL, Diener HC, Gorelick PB, Shuaib A, Solberg Y, Thackeray L, Savic M, Janelidze T, Zarqua N, Yarnitsky D, Molina CA, ImpACT-24B investigators. PMID: 31133406.
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Sphenopalatine Ganglion Stimulation to Augment Cerebral Blood Flow: A Randomized, Sham-Controlled Trial. Stroke. 2019 Aug; 50(8):2108-2117. Bornstein NM, Saver JL, Diener HC, Gorelick PB, Shuaib A, Solberg Y, Devlin T, Leung T, Molina CA, ImpACT-24A Investigators. PMID: 31117920.
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A national economic and clinical model for ischemic stroke care development in Saudi Arabia: A call for change. Int J Stroke. 2019 10; 14(8):835-842. Al-Senani F, Al-Johani M, Salawati M, ElSheikh S, AlQahtani M, Muthana J, AlZahrani S, Shore J, Taylor M, Ravest VS, Eggington S, Cuche M, Davies H, Lobotesis K, Saver JL. PMID: 31122171; PMCID: PMC6823921.
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Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. N Engl J Med. 2019 05 16; 380(20):1906-1917. Diener HC, Sacco RL, Easton JD, Granger CB, Bernstein RA, Uchiyama S, Kreuzer J, Cronin L, Cotton D, Grauer C, Brueckmann M, Chernyatina M, Donnan G, Ferro JM, Grond M, Kallmünzer B, Krupinski J, Lee BC, Lemmens R, Masjuan J, Odinak M, Saver JL, Schellinger PD, Toni D, Toyoda K, RE-SPECT ESUS Steering Committee and Investigators. PMID: 31091372.
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Efficacy of endovascular thrombectomy in patients with M2 segment middle cerebral artery occlusions: meta-analysis of data from the HERMES Collaboration. J Neurointerv Surg. 2019 Nov; 11(11):1065-1069. Menon BK, Hill MD, Davalos A, Roos YBWEM, Campbell BCV, Dippel DWJ, Guillemin F, Saver JL, van der Lugt A, Demchuk AM, Muir K, Brown S, Jovin T, Mitchell P, White P, Bracard S, Goyal M. PMID: 30975736.
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Comparison of Clinical Care and In-Hospital Outcomes of Asian American and White Patients With Acute Ischemic Stroke. JAMA Neurol. 2019 04 01; 76(4):430-439. Song S, Liang L, Fonarow GC, Smith EE, Bhatt DL, Matsouaka RA, Xian Y, Schwamm LH, Saver JL. PMID: 30667466; PMCID: PMC6459126.
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Use, Temporal Trends, and Outcomes of Endovascular Therapy After Interhospital Transfer in the United States. Circulation. 2019 03 26; 139(13):1568-1577. Shah S, Xian Y, Sheng S, Zachrison KS, Saver JL, Sheth KN, Fonarow GC, Schwamm LH, Smith EE. PMID: 30700144; PMCID: PMC6816244.
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The Addition of Atrial Fibrillation to the Los Angeles Motor Scale May Improve Prediction of Large Vessel Occlusion. J Neuroimaging. 2019 07; 29(4):463-466. Narwal P, Chang AD, Mac Grory B, Jayaraman M, Madsen T, Paolucci G, Cutting S, Burton T, Dakay K, Schomer A, Rostanski S, Noorian AR, Nour M, Liebeskind DS, Saver J, Furie K, Yaghi S. PMID: 30900276.
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Impact of procedural time on clinical and angiographic outcomes in patients with acute ischemic stroke receiving endovascular treatment. J Neurointerv Surg. 2019 Oct; 11(10):984-988. Hassan AE, Shariff U, Saver JL, Goyal M, Liebeskind D, Jahan R, Qureshi AI. PMID: 30842302.
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Impact of Balloon Guide Catheter Use on Clinical and Angiographic Outcomes in the STRATIS Stroke Thrombectomy Registry. Stroke. 2019 03; 50(3):697-704. Zaidat OO, Mueller-Kronast NH, Hassan AE, Haussen DC, Jadhav AP, Froehler MT, Jahan R, Ali Aziz-Sultan M, Klucznik RP, Saver JL, Hellinger FR, Yavagal DR, Yao TL, Gupta R, Martin CO, Bozorgchami H, Kaushal R, Nogueira RG, Gandhi RH, Peterson EC, Dashti S, Given CA, Mehta BP, Deshmukh V, Starkman S, Linfante I, McPherson SH, Kvamme P, Grobelny TJ, Hussain MS, Thacker I, Vora N, Chen PR, Monteith SJ, Ecker RD, Schirmer CM, Sauvageau E, Chebl AB, Derdeyn CP, Maidan L, Badruddin A, Siddiqui AH, Dumont TM, Alhajeri A, Taqi MA, Asi K, Carpenter J, Boulos A, Jindal G, Puri AS, Chitale R, Deshaies EM, Robinson D, Kallmes DF, Baxter BW, Jumaa M, Sunenshine P, Majjhoo A, English JD, Suzuki S, Fessler RD, Delgado-Almandoz J, Martin JC, Liebeskind DS, STRATIS Investigators. PMID: 30776994.
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Rapid Alteplase Administration Improves Functional Outcomes in Patients With Stroke due to Large Vessel Occlusions. Stroke. 2019 03; 50(3):645-651. Goyal M, Almekhlafi M, Dippel DW, Campbell BCV, Muir K, Demchuk AM, Bracard S, Davalos A, Guillemin F, Jovin TG, Menon BK, Mitchell PJ, Brown S, White P, Majoie CBLM, Saver JL, Hill MD, HERMES Collaborators. PMID: 30760169.
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Number Needed to Treat: Conveying the Likelihood of a Therapeutic Effect. JAMA. 2019 02 26; 321(8):798-799. Saver JL, Lewis RJ. PMID: 30730545.
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Relation of Admission Blood Pressure to In-hospital and 90-Day Outcomes in Patients Presenting With Transient Ischemic Attack. Am J Cardiol. 2019 04 01; 123(7):1083-1095. Bangalore S, Schwamm LH, Smith EE, Hellkamp AS, Xian Y, Schulte PJ, Saver JL, Fonarow GC, Bhatt DL, Get With The Guidelines-Stroke Steering Committee and Investigators. PMID: 30685057.
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Components and Trends in Door to Treatment Times for Endovascular Therapy in Get With The Guidelines-Stroke Hospitals. Circulation. 2019 01 08; 139(2):169-179. Menon BK, Xu H, Cox M, Saver JL, Goyal M, Peterson E, Xian Y, Matsuoka R, Jehan R, Yavagal D, Gupta R, Mehta B, Bhatt DL, Fonarow GC, Schwamm LH, Smith EE. PMID: 30586703.
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Comparative Effectiveness of Aspirin and Clopidogrel Versus Aspirin in Acute Minor Stroke or Transient Ischemic Attack. Stroke. 2019 Jan; 50(1):101-109. Kim JT, Park MS, Choi KH, Cho KH, Kim BJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Nah HW, Park TH, Park SS, Lee KB, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Ryu WS, Choi JC, Kwon JH, Kim WJ, Shin DI, Yeo MJ, Sohn SI, Hong JH, Lee JS, Lee J, Saver JL, Johnston SC, Bae HJ. PMID: 30580722.
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Response by Saver et al to Letter Regarding Article, "Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Ischemic Stroke: A Topical Review". Stroke. 2018 12; 49(12):e336. Saver JL, Mattle HP, Thaler D. PMID: 30571441.
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Letter by Berry et al Regarding Article, "Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials: A Simulation Study". Stroke. 2018 12; 49(12):e337. Berry S, Nogueira R, Saver JL. PMID: 30571446.
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Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data. Lancet Neurol. 2019 01; 18(1):46-55. Campbell BCV, Majoie CBLM, Albers GW, Menon BK, Yassi N, Sharma G, van Zwam WH, van Oostenbrugge RJ, Demchuk AM, Guillemin F, White P, Dávalos A, van der Lugt A, Butcher KS, Cherifi A, Marquering HA, Cloud G, Macho Fernández JM, Madigan J, Oppenheim C, Donnan GA, Roos YBWEM, Shankar J, Lingsma H, Bonafé A, Raoult H, Hernández-Pérez M, Bharatha A, Jahan R, Jansen O, Richard S, Levy EI, Berkhemer OA, Soudant M, Aja L, Davis SM, Krings T, Tisserand M, San Román L, Tomasello A, Beumer D, Brown S, Liebeskind DS, Bracard S, Muir KW, Dippel DWJ, Goyal M, Saver JL, Jovin TG, Hill MD, Mitchell PJ, HERMES collaborators. PMID: 30413385.
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Quality of Care and Outcomes for Patients With Stroke in the United States Admitted During the International Stroke Conference. J Am Heart Assoc. 2018 11 06; 7(21):e009842. Messé SR, Mullen MT, Cox M, Fonarow GC, Smith EE, Saver JL, Reeves MJ, Bhatt DL, Matsouaka R, Schwamm LH. PMID: 30376750; PMCID: PMC6404171.
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Differential Expression of Vascular Endothelial Growth Factor-A165 Isoforms Between Intracranial Atherosclerosis and Moyamoya Disease. J Stroke Cerebrovasc Dis. 2019 Feb; 28(2):360-368. Jiang H, Toscano JF, Schiraldi M, Song SS, Schlick KH, Dumitrascu OM, Liou R, Lyden PD, Pan J, Zhan R, Saver JL, Gonzalez NR. PMID: 30392834; PMCID: PMC6786492.
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Frequency, Predictors, and Outcomes of Prehospital and Early Postarrival Neurological Deterioration in Acute Stroke: Exploratory Analysis of the FAST-MAG Randomized Clinical Trial. JAMA Neurol. 2018 11 01; 75(11):1364-1374. Shkirkova K, Saver JL, Starkman S, Wong G, Weng J, Hamilton S, Liebeskind DS, Eckstein M, Stratton S, Pratt F, Conwit R, Sanossian N, FAST-MAG Trial Coordinators and Investigators. PMID: 30039165; PMCID: PMC6248118.
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Impact of Hyperglycemia According to the Collateral Status on Outcomes in Mechanical Thrombectomy. Stroke. 2018 11; 49(11):2706-2714. Kim JT, Liebeskind DS, Jahan R, Menon BK, Goyal M, Nogueira RG, Pereira VM, Gralla J, Saver JL. PMID: 30355207.
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Intraosseous Administration of Tissue Plasminogen Activator on a Mobile Stroke Unit. Prehosp Emerg Care. 2019 Jul-Aug; 23(4):447-452. Bowry R, Nour M, Kus T, Parker S, Stephenson J, Saver J, Grotta JC, Ostermayer D. PMID: 30235055.
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International Comparison of Patient Characteristics and Quality of Care for Ischemic Stroke: Analysis of the China National Stroke Registry and the American Heart Association Get With The Guidelines--Stroke Program. J Am Heart Assoc. 2018 10 16; 7(20):e010623. Wangqin R, Laskowitz DT, Wang Y, Li Z, Wang Y, Liu L, Liang L, Matsouaka RA, Saver JL, Fonarow GC, Bhatt DL, Smith EE, Schwamm LH, Prvu Bettger J, Hernandez AF, Peterson ED, Xian Y. PMID: 30371291; PMCID: PMC6474951.
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Handling of Missing Outcome Data in Acute Stroke Trials: Advantages of Multiple Imputation Using Baseline and Postbaseline Variables. J Stroke Cerebrovasc Dis. 2018 Dec; 27(12):3662-3669. Young-Saver DF, Gornbein J, Starkman S, Saver JL. PMID: 30297167.
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Volumetric and Spatial Accuracy of Computed Tomography Perfusion Estimated Ischemic Core Volume in Patients With Acute Ischemic Stroke. Stroke. 2018 10; 49(10):2368-2375. Hoving JW, Marquering HA, Majoie CBLM, Yassi N, Sharma G, Liebeskind DS, van der Lugt A, Roos YB, van Zwam W, van Oostenbrugge RJ, Goyal M, Saver JL, Jovin TG, Albers GW, Davalos A, Hill MD, Demchuk AM, Bracard S, Guillemin F, Muir KW, White P, Mitchell PJ, Donnan GA, Davis SM, Campbell BCV. PMID: 30355095.
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Patent foramen ovale increases stroke risk in older people. Nat Rev Neurol. 2018 Oct; 14(10):573-574. Mattle HP, Saver JL. PMID: 30054555.
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Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data. Lancet Neurol. 2018 10; 17(10):895-904. Román LS, Menon BK, Blasco J, Hernández-Pérez M, Dávalos A, Majoie CBLM, Campbell BCV, Guillemin F, Lingsma H, Anxionnat R, Epstein J, Saver JL, Marquering H, Wong JH, Lopes D, Reimann G, Desal H, Dippel DWJ, Coutts S, du Mesnil de Rochemont R, Yavagal D, Ferre JC, Roos YBWEM, Liebeskind DS, Lenthall R, Molina C, Al Ajlan FS, Reddy V, Dowlatshahi D, Sourour NA, Oppenheim C, Mitha AP, Davis SM, Weimar C, van Oostenbrugge RJ, Cobo E, Kleinig TJ, Donnan GA, van der Lugt A, Demchuk AM, Berkhemer OA, Boers AMM, Ford GA, Muir KW, Brown BS, Jovin T, van Zwam WH, Mitchell PJ, Hill MD, White P, Bracard S, Goyal M, HERMES collaborators. PMID: 30264728.
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Shock Index Predicts Patient-Related Clinical Outcomes in Stroke. J Am Heart Assoc. 2018 09 18; 7(18):e007581. Myint PK, Sheng S, Xian Y, Matsouaka RA, Reeves MJ, Saver JL, Bhatt DL, Fonarow GC, Schwamm LH, Smith EE. PMID: 30371191; PMCID: PMC6222962.
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eTICI reperfusion: defining success in endovascular stroke therapy. J Neurointerv Surg. 2019 May; 11(5):433-438. Liebeskind DS, Bracard S, Guillemin F, Jahan R, Jovin TG, Majoie CB, Mitchell PJ, van der Lugt A, Menon BK, San Román L, Campbell BC, Muir KW, Hill MD, Dippel DW, Saver JL, Demchuk AM, Dávalos A, White P, Brown S, Goyal M, HERMES Collaborators. PMID: 30194109.
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Regional Contributions to Poststroke Disability in Endovascular Therapy. Interv Neurol. 2018 Oct; 7(6):533-543. Sheth SA, Malhotra K, Liebeskind DS, Liang CW, Yoo AJ, Jahan R, Nogueira RG, Pereira V, Gralla J, Albers G, Goyal M, Saver JL. PMID: 30410533; PMCID: PMC6216699.
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Impact of Anesthetic Management on Safety and Outcomes Following Mechanical Thrombectomy for Ischemic Stroke in SWIFT PRIME Cohort. Front Neurol. 2018; 9:702. Eker OF, Saver JL, Goyal M, Jahan R, Levy EI, Nogueira RG, Yavagal DR, Bonafé A, SWIFT PRIME investigators. PMID: 30210431; PMCID: PMC6123376.
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Striving for Ideal Cardiovascular and Brain Health: It Is Never Too Early or Too Late. JAMA. 2018 08 21; 320(7):645-647. Saver JL, Cushman M. PMID: 30140858.
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The Frequency of Substantial Salvageable Penumbra in Thrombectomy-ineligible Patients with Acute Stroke. J Neuroimaging. 2018 11; 28(6):676-682. Bahr Hosseini M, Woolf G, Sharma LK, Hinman JD, Rao NM, Yoo B, Jahan R, Starkman S, Nour M, Raychev R, Liebeskind DS, Saver JL. PMID: 30010229.
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Effect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits: The PRISMS Randomized Clinical Trial. JAMA. 2018 07 10; 320(2):156-166. Khatri P, Kleindorfer DO, Devlin T, Sawyer RN, Starr M, Mejilla J, Broderick J, Chatterjee A, Jauch EC, Levine SR, Romano JG, Saver JL, Vagal A, Purdon B, Devenport J, Pavlov A, Yeatts SD, PRISMS Investigators. PMID: 29998337; PMCID: PMC6583516.
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Cost-effectiveness analysis of mechanical thrombectomy with stent retriever in the treatment of acute ischemic stroke in Italy. J Med Econ. 2018 Sep; 21(9):902-911. Ruggeri M, Basile M, Zini A, Mangiafico S, Agostoni EC, Lobotesis K, Saver J, Coretti S, Drago C, Cicchetti A. PMID: 29882711.
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Clinical Significance of Acute and Serial Platelet Function Testing in Acute Ischemic Stroke. J Am Heart Assoc. 2018 06 01; 7(11). Kim JT, Choi KH, Park MS, Lee JS, Saver JL, Cho KH. PMID: 29858358; PMCID: PMC6015392.
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A review of the diagnosis and management of vertebral basilar (posterior) circulation disease. Surg Neurol Int. 2018; 9:106. Ausman JI, Liebeskind DS, Gonzalez N, Saver J, Martin N, Villablanca JP, Vespa P, Duckwiler G, Jahan R, Niu T, Salamon N, Yoo B, Tateshima S, Buitrago Blanco MM, Starkman S. PMID: 29930872; PMCID: PMC5991286.
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Clinical Performance Measures for Adults Hospitalized With Intracerebral Hemorrhage: Performance Measures for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2018 07; 49(7):e243-e261. Hemphill JC, Adeoye OM, Alexander DN, Alexandrov AW, Amin-Hanjani S, Cushman M, George MG, LeRoux PD, Mayer SA, Qureshi AI, Saver JL, Schwamm LH, Sheth KN, Tirschwell D, AHA/ASA Stroke Performance Oversight Committee. PMID: 29786566.
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Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Ischemic Stroke: A Topical Review. Stroke. 2018 06; 49(6):1541-1548. Saver JL, Mattle HP, Thaler D. PMID: 29760277.
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Direct mechanical thrombectomy in tPA-ineligible and -eligible patients versus the bridging approach: a meta-analysis. J Neurointerv Surg. 2019 Jan; 11(1):20-27. Kaesmacher J, Mordasini P, Arnold M, López-Cancio E, Cerdá N, Boeckh-Behrens T, Kleine JF, Goyal M, Hill MD, Pereira VM, Saver JL, Gralla J, Fischer U. PMID: 29705773; PMCID: PMC6327861.
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Cost-effectiveness of percutaneous patent foramen ovale closure as secondary stroke prevention. J Med Econ. 2018 Jul; 21(7):656-665. Tirschwell DL, Turner M, Thaler D, Choulerton J, Marks D, Carroll J, MacDonald L, Smalling RW, Koullick M, Gu NY, Saver JL. PMID: 29564942.
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Primary Results of the Multicenter ARISE II Study (Analysis of Revascularization in Ischemic Stroke With EmboTrap). Stroke. 2018 05; 49(5):1107-1115. Zaidat OO, Bozorgchami H, Ribó M, Saver JL, Mattle HP, Chapot R, Narata AP, Francois O, Jadhav AP, Grossberg JA, Riedel CH, Tomasello A, Clark WM, Nordmeyer H, Lin E, Nogueira RG, Yoo AJ, Jovin TG, Siddiqui AH, Bernard T, Claffey M, Andersson T. PMID: 29643261.
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Frequency of Patent Foramen Ovale and Migraine in Patients With Cryptogenic Stroke. Stroke. 2018 05; 49(5):1123-1128. West BH, Noureddin N, Mamzhi Y, Low CG, Coluzzi AC, Shih EJ, Gevorgyan Fleming R, Saver JL, Liebeskind DS, Charles A, Tobis JM. PMID: 29636424; PMCID: PMC5915909.
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Alteplase for the treatment of acute ischemic stroke in patients with low National Institutes of Health Stroke Scale and not clearly disabling deficits (Potential of rtPA for Ischemic Strokes with Mild Symptoms PRISMS): Rationale and design. Int J Stroke. 2018 08; 13(6):654-661. Yeatts SD, Broderick JP, Chatterjee A, Jauch EC, Levine SR, Romano JG, Saver JL, Vagal A, Purdon B, Devenport J, Khatri P. PMID: 29570044.
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Apparent Diffusion Coefficient Signal Intensity Ratio Predicts the Effect of Revascularization on Ischemic Cerebral Edema. Cerebrovasc Dis. 2018; 45(3-4):93-100. Bevers MB, Battey TWK, Ostwaldt AC, Jahan R, Saver JL, Kimberly WT, Kidwell CS. PMID: 29533946; PMCID: PMC5951748.
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Early Blood-Brain Barrier Disruption after Mechanical Thrombectomy in Acute Ischemic Stroke. J Neuroimaging. 2018 05; 28(3):283-288. Shi ZS, Duckwiler GR, Jahan R, Tateshima S, Szeder V, Saver JL, Kim D, Sharma LK, Vespa PM, Salamon N, Villablanca JP, Viñuela F, Feng L, Loh Y, Liebeskind DS. PMID: 29484769.
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Los Angeles Motor Scale to Identify Large Vessel Occlusion: Prehospital Validation and Comparison With Other Screens. Stroke. 2018 03; 49(3):565-572. Noorian AR, Sanossian N, Shkirkova K, Liebeskind DS, Eckstein M, Stratton SJ, Pratt FD, Conwit R, Chatfield F, Sharma LK, Restrepo L, Valdes-Sueiras M, Kim-Tenser M, Starkman S, Saver JL, FAST-MAG Trial Investigators and Coordinators. PMID: 29459391; PMCID: PMC5829024.
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Association of Intracerebral Hemorrhage Among Patients Taking Non-Vitamin K Antagonist vs Vitamin K Antagonist Oral Anticoagulants With In-Hospital Mortality. JAMA. 2018 02 06; 319(5):463-473. Inohara T, Xian Y, Liang L, Matsouaka RA, Saver JL, Smith EE, Schwamm LH, Reeves MJ, Hernandez AF, Bhatt DL, Peterson ED, Fonarow GC. PMID: 29372247; PMCID: PMC5839299.
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Folic Acid in Stroke Prevention in Countries without Mandatory Folic Acid Food Fortification: A Meta-Analysis of Randomized Controlled Trials. J Stroke. 2018 Jan; 20(1):99-109. Hsu CY, Chiu SW, Hong KS, Saver JL, Wu YL, Lee JD, Lee M, Ovbiagele B. PMID: 29402063; PMCID: PMC5836580.
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Association Between Hyperacute Stage Blood Pressure Variability and Outcome in Patients With Spontaneous Intracerebral Hemorrhage. Stroke. 2018 02; 49(2):348-354. Chung PW, Kim JT, Sanossian N, Starkmann S, Hamilton S, Gornbein J, Conwit R, Eckstein M, Pratt F, Stratton S, Liebeskind DS, Saver JL, FAST-MAG Investigators and Coordinators. PMID: 29301973.
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Trials of Patent Foramen Ovale Closure. N Engl J Med. 2017 12 28; 377(26):2600. Saver JL, RESPECT Trial Steering Committee. PMID: 29300445.
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Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data. Lancet Neurol. 2018 01; 17(1):47-53. Campbell BCV, van Zwam WH, Goyal M, Menon BK, Dippel DWJ, Demchuk AM, Bracard S, White P, Dávalos A, Majoie CBLM, van der Lugt A, Ford GA, de la Ossa NP, Kelly M, Bourcier R, Donnan GA, Roos YBWEM, Bang OY, Nogueira RG, Devlin TG, van den Berg LA, Clarençon F, Burns P, Carpenter J, Berkhemer OA, Yavagal DR, Pereira VM, Ducrocq X, Dixit A, Quesada H, Epstein J, Davis SM, Jansen O, Rubiera M, Urra X, Micard E, Lingsma HF, Naggara O, Brown S, Guillemin F, Muir KW, van Oostenbrugge RJ, Saver JL, Jovin TG, Hill MD, Mitchell PJ, HERMES collaborators. PMID: 29263006.
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Visual Aids for Patient, Family, and Physician Decision Making About Endovascular Thrombectomy for Acute Ischemic Stroke. Stroke. 2018 01; 49(1):90-97. Tokunboh I, Vales Montero M, Zopelaro Almeida MF, Sharma L, Starkman S, Szeder V, Jahan R, Liebeskind D, Gonzalez N, Demchuk A, Froehler MT, Goyal M, Lansberg MG, Lutsep H, Schwamm L, Saver JL. PMID: 29222229.
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Ischemic Strokes Due to Large-Vessel Occlusions Contribute Disproportionately to Stroke-Related Dependence and Death: A Review. Front Neurol. 2017; 8:651. Malhotra K, Gornbein J, Saver JL. PMID: 29250029; PMCID: PMC5715197.
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Relative cerebral blood volume is associated with collateral status and infarct growth in stroke patients in SWIFT PRIME. J Cereb Blood Flow Metab. 2018 10; 38(10):1839-1847. Arenillas JF, Cortijo E, García-Bermejo P, Levy EI, Jahan R, Liebeskind D, Goyal M, Saver JL, Albers GW. PMID: 29135347; PMCID: PMC6168913.
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Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. N Engl J Med. 2018 01 04; 378(1):11-21. Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA, Hassan AE, Millan M, Levy EI, Mitchell P, Chen M, English JD, Shah QA, Silver FL, Pereira VM, Mehta BP, Baxter BW, Abraham MG, Cardona P, Veznedaroglu E, Hellinger FR, Feng L, Kirmani JF, Lopes DK, Jankowitz BT, Frankel MR, Costalat V, Vora NA, Yoo AJ, Malik AM, Furlan AJ, Rubiera M, Aghaebrahim A, Olivot JM, Tekle WG, Shields R, Graves T, Lewis RJ, Smith WS, Liebeskind DS, Saver JL, Jovin TG, DAWN Trial Investigators. PMID: 29129157.
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Mechanical thrombectomy for acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery: a meta-analysis. J Neurointerv Surg. 2018 Jul; 10(7):620-624. Saber H, Narayanan S, Palla M, Saver JL, Nogueira RG, Yoo AJ, Sheth SA. PMID: 29127196.
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Microcatheter contrast injection in stent retriever neurothrombectomy is safe and useful: insights from SWIFT PRIME. J Neurointerv Surg. 2018 Jul; 10(7):615-619. Raychev R, Jahan R, Saver JL, Nogueira RG, Goyal M, Pereira VM, Levy E, Yavagal DR, Cognard C, Liebeskind D. PMID: 29127195.
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Antiangiogenesis and medical therapy failure in intracranial atherosclerosis. Angiogenesis. 2018 02; 21(1):23-35. Gonzalez NR, Liou R, Kurth F, Jiang H, Saver J. PMID: 28993906; PMCID: PMC5831393.
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Increase in Endovascular Therapy in Get With The Guidelines-Stroke After the Publication of Pivotal Trials. Circulation. 2017 Dec 12; 136(24):2303-2310. Smith EE, Saver JL, Cox M, Liang L, Matsouaka R, Xian Y, Bhatt DL, Fonarow GC, Schwamm LH. PMID: 28982689.
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Is Risk-Standardized In-Hospital Stroke Mortality an Adequate Proxy for Risk-Standardized 30-Day Stroke Mortality Data? Findings From Get With The Guidelines-Stroke. Circ Cardiovasc Qual Outcomes. 2017 Oct; 10(10). Reeves MJ, Fonarow GC, Xu H, Matsouaka RA, Xian Y, Saver J, Schwamm L, Smith EE. PMID: 29021333.
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Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke). Circulation. 2017 Dec 12; 136(24):2311-2321. Froehler MT, Saver JL, Zaidat OO, Jahan R, Aziz-Sultan MA, Klucznik RP, Haussen DC, Hellinger FR, Yavagal DR, Yao TL, Liebeskind DS, Jadhav AP, Gupta R, Hassan AE, Martin CO, Bozorgchami H, Kaushal R, Nogueira RG, Gandhi RH, Peterson EC, Dashti SR, Given CA, Mehta BP, Deshmukh V, Starkman S, Linfante I, McPherson SH, Kvamme P, Grobelny TJ, Hussain MS, Thacker I, Vora N, Chen PR, Monteith SJ, Ecker RD, Schirmer CM, Sauvageau E, Abou-Chebl A, Derdeyn CP, Maidan L, Badruddin A, Siddiqui AH, Dumont TM, Alhajeri A, Taqi MA, Asi K, Carpenter J, Boulos A, Jindal G, Puri AS, Chitale R, Deshaies EM, Robinson DH, Kallmes DF, Baxter BW, Jumaa MA, Sunenshine P, Majjhoo A, English JD, Suzuki S, Fessler RD, Delgado Almandoz JE, Martin JC, Mueller-Kronast NH, STRATIS Investigators. PMID: 28943516; PMCID: PMC5732640.
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Minimal Clinically Important Difference for Safe and Simple Novel Acute Ischemic Stroke Therapies. Stroke. 2017 11; 48(11):2946-2951. Cranston JS, Kaplan BD, Saver JL. PMID: 28931621.
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Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke. N Engl J Med. 2017 09 14; 377(11):1022-1032. Saver JL, Carroll JD, Thaler DE, Smalling RW, MacDonald LA, Marks DS, Tirschwell DL, RESPECT Investigators. PMID: 28902590.
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Direct Mechanical Thrombectomy Versus Combined Intravenous and Mechanical Thrombectomy in Large-Artery Anterior Circulation Stroke: A Topical Review. Stroke. 2017 10; 48(10):2912-2918. Fischer U, Kaesmacher J, Mendes Pereira V, Chapot R, Siddiqui AH, Froehler MT, Cognard C, Furlan AJ, Saver JL, Gralla J. PMID: 28887391.
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A randomized controlled study of intravenous fluid in acute ischemic stroke. Clin Neurol Neurosurg. 2017 Oct; 161:98-103. Suwanwela NC, Chutinet A, Mayotarn S, Thanapiyachaikul R, Chaisinanunkul N, Asawavichienjinda T, Muengtaweepongsa S, Nilanont Y, Samajarn J, Watcharasaksilp K, Tiamkao S, Vongvasinkul P, Charnwut S, Saver JL, IVIS Study Group. PMID: 28866264.
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Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry. Stroke. 2017 10; 48(10):2760-2768. Mueller-Kronast NH, Zaidat OO, Froehler MT, Jahan R, Aziz-Sultan MA, Klucznik RP, Saver JL, Hellinger FR, Yavagal DR, Yao TL, Liebeskind DS, Jadhav AP, Gupta R, Hassan AE, Martin CO, Bozorgchami H, Kaushal R, Nogueira RG, Gandhi RH, Peterson EC, Dashti SR, Given CA, Mehta BP, Deshmukh V, Starkman S, Linfante I, McPherson SH, Kvamme P, Grobelny TJ, Hussain MS, Thacker I, Vora N, Chen PR, Monteith SJ, Ecker RD, Schirmer CM, Sauvageau E, Abou-Chebl A, Derdeyn CP, Maidan L, Badruddin A, Siddiqui AH, Dumont TM, Alhajeri A, Taqi MA, Asi K, Carpenter J, Boulos A, Jindal G, Puri AS, Chitale R, Deshaies EM, Robinson DH, Kallmes DF, Baxter BW, Jumaa MA, Sunenshine P, Majjhoo A, English JD, Suzuki S, Fessler RD, Delgado Almandoz JE, Martin JC, Haussen DC, STRATIS Investigators. PMID: 28830971.
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Utilization of Statins Beyond the Initial Period After Stroke and 1-Year Risk of Recurrent Stroke. J Am Heart Assoc. 2017 Aug 02; 6(8). Lee M, Saver JL, Wu YL, Tang SC, Lee JD, Rao NM, Wang HH, Jeng JS, Lee TH, Chen PC, Ovbiagele B. PMID: 28768645; PMCID: PMC5586426.
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Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis. Stroke. 2017 08; 48(8):2084-2090. Charidimou A, Turc G, Oppenheim C, Yan S, Scheitz JF, Erdur H, Klinger-Gratz PP, El-Koussy M, Takahashi W, Moriya Y, Wilson D, Kidwell CS, Saver JL, Sallem A, Moulin S, Edjlali-Goujon M, Thijs V, Fox Z, Shoamanesh A, Albers GW, Mattle HP, Benavente OR, Jäger HR, Ambler G, Aoki J, Baron JC, Kimura K, Kakuda W, Takizawa S, Jung S, Nolte CH, Lou M, Cordonnier C, Werring DJ. PMID: 28720659.
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Reperfusion after ischemic stroke is associated with reduced brain edema. J Cereb Blood Flow Metab. 2018 10; 38(10):1807-1817. Irvine HJ, Ostwaldt AC, Bevers MB, Dixon S, Battey TW, Campbell BC, Davis SM, Donnan GA, Sheth KN, Jahan R, Saver JL, Kidwell CS, Kimberly WT. PMID: 28731381; PMCID: PMC6168909.
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Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis. Stroke. 2017 09; 48(9):2610-2613. Lee M, Saver JL, Hong KS, Rao NM, Wu YL, Ovbiagele B. PMID: 28701574.
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Response by Lee et al to Letter Regarding Article, "Pioglitazone for Secondary Stroke Prevention: A Systematic Review and Meta-Analysis". Stroke. 2017 07; 48(7):e172. Lee M, Saver JL, Ovbiagele B. PMID: 28619990.
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Paramedic Initiation of Neuroprotective Agent Infusions: Successful Achievement of Target Blood Levels and Attained Level Effect on Clinical Outcomes in the FAST-MAG Pivotal Trial (Field Administration of Stroke Therapy - Magnesium). Stroke. 2017 07; 48(7):1901-1907. Shkirkova K, Starkman S, Sanossian N, Eckstein M, Stratton S, Pratt F, Conwit R, Hamilton S, Sharma L, Liebeskind D, Restrepo L, Valdes-Sueiras M, Saver JL, FAST-MAG Investigators and Coordinators. PMID: 28583999.
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Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods. Int J Stroke. 2017 08; 12(6):641-652. Jovin TG, Saver JL, Ribo M, Pereira V, Furlan A, Bonafe A, Baxter B, Gupta R, Lopes D, Jansen O, Smith W, Gress D, Hetts S, Lewis RJ, Shields R, Berry SM, Graves TL, Malisch T, Rai A, Sheth KN, Liebeskind DS, Nogueira RG. PMID: 28569123.
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The American Heart Association's Get With the Guidelines (GWTG)-Stroke development and impact on stroke care. Stroke Vasc Neurol. 2017 Jun; 2(2):94-105. Ormseth CH, Sheth KN, Saver JL, Fonarow GC, Schwamm LH. PMID: 28959497; PMCID: PMC5600018.
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Cost of Alteplase Has More Than Doubled Over the Past Decade. Stroke. 2017 07; 48(7):2000-2002. Kleindorfer D, Broderick J, Demaerschalk B, Saver J. PMID: 28536176.
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Efficacy of Stent-Retriever Thrombectomy in Magnetic Resonance Imaging Versus Computed Tomographic Perfusion-Selected Patients in SWIFT PRIME Trial (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke). Stroke. 2017 06; 48(6):1560-1566. Menjot de Champfleur N, Saver JL, Goyal M, Jahan R, Diener HC, Bonafe A, Levy EI, Pereira VM, Cognard C, Yavagal DR, Albers GW. PMID: 28465460.
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A Dedicated Spanish Language Line Increases Enrollment of Hispanics Into Prehospital Clinical Research. Stroke. 2017 05; 48(5):1389-1391. Sanossian N, Rosenberg L, Liebeskind DS, Starkman S, Eckstein M, Stratton S, Pratt FD, Hamilton S, Kim-Tenser M, Sharma LK, Restrepo L, Valdes-Suieras M, Conwit R, Saver JL, FAST-MAG Investigators and Coordinators. PMID: 28389617.
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Feasibility and utility of an integrated medical imaging and informatics smartphone system for management of acute stroke. Int J Stroke. 2017 12; 12(9):953-960. Shkirkova K, Akam EY, Huang J, Sheth SA, Nour M, Liang CW, McManus M, Trinh V, Duckwiler G, Tarpley J, Vinuela F, Saver JL, UCLA Stroke Systems of Care Study Group. PMID: 28358291.
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Time to Endovascular Thrombectomy for Acute Stroke-Reply. JAMA. 2017 03 21; 317(11):1175-1176. Saver JL, Goyal M, Hill MD, HERMES Collaborators. PMID: 28324086.
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Predictive Value of RAPID Assessed Perfusion Thresholds on Final Infarct Volume in SWIFT PRIME (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment). Stroke. 2017 04; 48(4):932-938. Mokin M, Levy EI, Saver JL, Siddiqui AH, Goyal M, Bonafé A, Cognard C, Jahan R, Albers GW, SWIFT PRIME Investigators. PMID: 28283606.
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ASPECTS-based reperfusion status on arterial spin labeling is associated with clinical outcome in acute ischemic stroke patients. J Cereb Blood Flow Metab. 2018 03; 38(3):382-392. Yu S, Ma SJ, Liebeskind DS, Yu D, Li N, Qiao XJ, Shao X, Yan L, Yoo B, Scalzo F, Hinman JD, Sharma LK, Rao N, Jahan R, Tateshima S, Duckwiler GR, Saver JL, Salamon N, Wang DJ. PMID: 28266894; PMCID: PMC5851135.
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Combined Intravenous Thrombolysis and Thrombectomy vs Thrombectomy Alone for Acute Ischemic Stroke: A Pooled Analysis of the SWIFT and STAR Studies. JAMA Neurol. 2017 Mar 01; 74(3):268-274. Coutinho JM, Liebeskind DS, Slater LA, Nogueira RG, Clark W, Dávalos A, Bonafé A, Jahan R, Fischer U, Gralla J, Saver JL, Pereira VM. PMID: 28097310.
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Penumbral salvage and thrombolysis outcome: a drop of brain, a week of life. Brain. 2017 03 01; 140(3):519-522. Saver JL. PMID: 28364555.
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Delays in Door-to-Needle Times and Their Impact on Treatment Time and Outcomes in Get With The Guidelines-Stroke. Stroke. 2017 04; 48(4):946-954. Kamal N, Sheng S, Xian Y, Matsouaka R, Hill MD, Bhatt DL, Saver JL, Reeves MJ, Fonarow GC, Schwamm LH, Smith EE. PMID: 28228574.
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Mobile stroke units for prehospital thrombolysis, triage, and beyond: benefits and challenges. Lancet Neurol. 2017 03; 16(3):227-237. Fassbender K, Grotta JC, Walter S, Grunwald IQ, Ragoschke-Schumm A, Saver JL. PMID: 28229894.
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Effect of statin use on clinical outcomes in ischemic stroke patients with atrial fibrillation. Medicine (Baltimore). 2017 Feb; 96(5):e5918. Wu YL, Saver JL, Chen PC, Lee JD, Wang HH, Rao NM, Lee M, Ovbiagele B. PMID: 28151869; PMCID: PMC5293432.
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Multiparametric Magnetic Resonance Imaging for Prediction of Parenchymal Hemorrhage in Acute Ischemic Stroke After Reperfusion Therapy. Stroke. 2017 03; 48(3):664-670. Nael K, Knitter JR, Jahan R, Gornbein J, Ajani Z, Feng L, Meyer BC, Schwamm LH, Yoo AJ, Marshall RS, Meyers PM, Yavagal DR, Wintermark M, Liebeskind DS, Guzy J, Starkman S, Saver JL, Kidwell CS. PMID: 28138001; PMCID: PMC5325250.
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Field Validation of the Los Angeles Motor Scale as a Tool for Paramedic Assessment of Stroke Severity. Stroke. 2017 02; 48(2):298-306. Kim JT, Chung PW, Starkman S, Sanossian N, Stratton SJ, Eckstein M, Pratt FD, Conwit R, Liebeskind DS, Sharma L, Restrepo L, Tenser MK, Valdes-Sueiras M, Gornbein J, Hamilton S, Saver JL, FAST-MAG Trial (Field Administration of Stroke Therapy–Magnesium) Nurse-Coordinators and Investigato. PMID: 28087807.
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Multi-delay ASL can identify leptomeningeal collateral perfusion in endovascular therapy of ischemic stroke. Oncotarget. 2017 Jan 10; 8(2):2437-2443. Lou X, Yu S, Scalzo F, Starkman S, Ali LK, Kim D, Rao NM, Hinman JD, Vespa PM, Jahan R, Tateshima S, Gonzalez NR, Duckwiler GR, Saver JL, Yoo B, Salamon N, Lyu J, Ma L, Wang DJ, Liebeskind DS. PMID: 27974692; PMCID: PMC5356813.
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Pioglitazone and cardiovascular outcomes in patients with insulin resistance, pre-diabetes and type 2 diabetes: a systematic review and meta-analysis. BMJ Open. 2017 01 05; 7(1):e013927. Liao HW, Saver JL, Wu YL, Chen TH, Lee M, Ovbiagele B. PMID: 28057658; PMCID: PMC5223642.
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Hospital Variation in Functional Recovery After Stroke. Circ Cardiovasc Qual Outcomes. 2017 01; 10(1). Bettger JP, Thomas L, Liang L, Xian Y, Bushnell CD, Saver JL, Fonarow GC, Peterson ED. PMID: 28096203.
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Use of Strategies to Improve Door-to-Needle Times With Tissue-Type Plasminogen Activator in Acute Ischemic Stroke in Clinical Practice: Findings from Target: Stroke. Circ Cardiovasc Qual Outcomes. 2017 01; 10(1). Xian Y, Xu H, Lytle B, Blevins J, Peterson ED, Hernandez AF, Smith EE, Saver JL, Messé SR, Paulsen M, Suter RE, Reeves MJ, Jauch EC, Schwamm LH, Fonarow GC. PMID: 28096207.
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Cost-Effectiveness of Solitaire Stent Retriever Thrombectomy for Acute Ischemic Stroke: Results From the SWIFT-PRIME Trial (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke). Stroke. 2017 02; 48(2):379-387. Shireman TI, Wang K, Saver JL, Goyal M, Bonafé A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Devlin TG, Lopes DK, Reddy VK, du Mesnil de Rochemont R, Jahan R, Vilain KA, House J, Lee JM, Cohen DJ, SWIFT-PRIME Investigators. PMID: 28028150; PMCID: PMC5461963.
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Differences in Acute Ischemic Stroke Quality of Care and Outcomes by Primary Stroke Center Certification Organization. Stroke. 2017 02; 48(2):412-419. Man S, Cox M, Patel P, Smith EE, Reeves MJ, Saver JL, Bhatt DL, Xian Y, Schwamm LH, Fonarow GC. PMID: 28008094.
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Pioglitazone for Secondary Stroke Prevention: A Systematic Review and Meta-Analysis. Stroke. 2017 02; 48(2):388-393. Lee M, Saver JL, Liao HW, Lin CH, Ovbiagele B. PMID: 27999139.
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Clinical Outcomes of Posterior Versus Anterior Circulation Infarction With Low National Institutes of Health Stroke Scale Scores. Stroke. 2017 01; 48(1):55-62. Kim JT, Park MS, Choi KH, Kim BJ, Han MK, Park TH, Park SS, Lee KB, Lee BC, Yu KH, Oh MS, Cha JK, Kim DH, Nah HW, Lee J, Lee SJ, Ko Y, Kim JG, Park JM, Kang K, Cho YJ, Hong KS, Choi JC, Kim DE, Ryu WS, Shin DI, Yeo MJ, Kim WJ, Lee J, Lee JS, Bae HJ, Saver JL, Cho KH. PMID: 27856952.
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Treatment With Tissue Plasminogen Activator in the Golden Hour and the Shape of the 4.5-Hour Time-Benefit Curve in the National United States Get With The Guidelines-Stroke Population. Circulation. 2017 Jan 10; 135(2):128-139. Kim JT, Fonarow GC, Smith EE, Reeves MJ, Navalkele DD, Grotta JC, Grau-Sepulveda MV, Hernandez AF, Peterson ED, Schwamm LH, Saver JL. PMID: 27815374.
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Selecting Patients for Intra-Arterial Therapy in the Context of a Clinical Trial for Neuroprotection. Stroke. 2016 12; 47(12):2979-2985. Lyden P, Weymer S, Coffey C, Cudkowicz M, Berg S, O'Brien S, Fisher M, Haley EC, Khatri P, Saver J, Levine S, Levy H, Rymer M, Wechsler L, Jadhav A, McNeil E, Waddy S, Pryor K. PMID: 27803392; PMCID: PMC5134840.
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Plasmin (Human) Administration in Acute Middle Cerebral Artery Ischemic Stroke: Phase 1/2a, Open-Label, Dose-Escalation, Safety Study. J Stroke Cerebrovasc Dis. 2017 Feb; 26(2):308-320. Mitchell PJ, Yan B, Brozman M, Ribo M, Marder V, Courtney KL, Saver JL, Plasmin Trial Investigators. PMID: 27793534.
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Heads Up! A Novel Provocative Maneuver to Guide Acute Ischemic Stroke Management. Interv Neurol. 2017 Mar; 6(1-2):8-15. Ali LK, Weng JK, Starkman S, Saver JL, Kim D, Ovbiagele B, Buck BH, Sanossian N, Vespa P, Bang OY, Jahan R, Duckwiler GR, Viñuela F, Liebeskind DS. PMID: 28611828; PMCID: PMC5465685.
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Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis. JAMA. 2016 Sep 27; 316(12):1279-88. Saver JL, Goyal M, van der Lugt A, Menon BK, Majoie CB, Dippel DW, Campbell BC, Nogueira RG, Demchuk AM, Tomasello A, Cardona P, Devlin TG, Frei DF, du Mesnil de Rochemont R, Berkhemer OA, Jovin TG, Siddiqui AH, van Zwam WH, Davis SM, Castaño C, Sapkota BL, Fransen PS, Molina C, van Oostenbrugge RJ, Chamorro Á, Lingsma H, Silver FL, Donnan GA, Shuaib A, Brown S, Stouch B, Mitchell PJ, Davalos A, Roos YB, Hill MD, HERMES Collaborators. PMID: 27673305.
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Characteristics and Outcomes of Very Elderly Enrolled in a Prehospital Stroke Research Study. Stroke. 2016 11; 47(11):2737-2741. Sanossian N, Apibunyopas KC, Liebeskind DS, Starkman S, Burgos AM, Conwit R, Eckstein M, Pratt F, Stratton S, Hamilton S, Saver JL, FAST-MAG (Field Administration of Stroke Therapy-Magnesium) Investigators and Coordinators. PMID: 27679533.
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Fluid-Attenuated Inversion Recovery Vascular Hyperintensity Topography, Novel Imaging Marker for Revascularization in Middle Cerebral Artery Occlusion. Stroke. 2016 11; 47(11):2763-2769. Liu D, Scalzo F, Rao NM, Hinman JD, Kim D, Ali LK, Saver JL, Sun W, Dai Q, Liu X, Liebeskind DS. PMID: 27659851; PMCID: PMC5079823.
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Cryptogenic Stroke. N Engl J Med. 2016 09 15; 375(11):e26. Saver JL. PMID: 27626542.
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Association of clot burden score with radiographic and clinical outcomes following Solitaire stent retriever thrombectomy: analysis of the SWIFT PRIME trial. J Neurointerv Surg. 2017 Oct; 9(10):929-932. Mokin M, Levy EI, Siddiqui AH, Goyal M, Nogueira RG, Yavagal DR, M Pereira V, Saver JL. PMID: 27634952.
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Why are acute ischemic stroke patients not receiving IV tPA? Results from a national registry. Neurology. 2016 Oct 11; 87(15):1565-1574. Messé SR, Khatri P, Reeves MJ, Smith EE, Saver JL, Bhatt DL, Grau-Sepulveda MV, Cox M, Peterson ED, Fonarow GC, Schwamm LH. PMID: 27629092; PMCID: PMC5067546.
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Hospital Variation in Home-Time After Acute Ischemic Stroke: Insights From the PROSPER Study (Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research). Stroke. 2016 10; 47(10):2627-33. O'Brien EC, Xian Y, Xu H, Wu J, Saver JL, Smith EE, Schwamm LH, Peterson ED, Reeves MJ, Bhatt DL, Maisch L, Hannah D, Lindholm B, Olson D, Prvu Bettger J, Pencina M, Hernandez AF, Fonarow GC. PMID: 27625383.
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Percutaneous left atrial appendage occlusion: the Munich consensus document on definitions, endpoints, and data collection requirements for clinical studies. Europace. 2017 Jan; 19(1):4-15. Tzikas A, Holmes DR, Gafoor S, Ruiz CE, Blomström-Lundqvist C, Diener HC, Cappato R, Kar S, Lee RJ, Byrne RA, Ibrahim R, Lakkireddy D, Soliman OI, Nabauer M, Schneider S, Brachmann J, Saver JL, Tiemann K, Sievert H, Camm AJ, Lewalter T. PMID: 27540038; PMCID: PMC5841559.
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Use and Outcomes of Intravenous Thrombolysis for Acute Ischemic Stroke in Patients ≥90 Years of Age. Stroke. 2016 09; 47(9):2347-54. Arora R, Salamon E, Katz JM, Cox M, Saver JL, Bhatt DL, Fonarow GC, Peterson ED, Smith EE, Schwamm LH, Xian Y, Libman RB. PMID: 27491734.
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The Rankin Focused Assessment-Ambulation: A Method to Score the Modified Rankin Scale with Emphasis on Walking Ability. J Stroke Cerebrovasc Dis. 2016 Sep; 25(9):2172-6. Patel RD, Starkman S, Hamilton S, Craig S, Grace A, Conwit R, Saver JL. PMID: 27450385.
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Prior Antithrombotic Use Is Associated With Favorable Mortality and Functional Outcomes in Acute Ischemic Stroke. Stroke. 2016 08; 47(8):2066-74. Myint PK, Hellkamp AS, Fonarow GC, Reeves MJ, Schwamm LH, Schulte PJ, Xian Y, Suter RE, Bhatt DL, Saver JL, Peterson ED, Smith EE. PMID: 27435402.
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Utilization of Emergent Neuroimaging for Thrombolysis-Eligible Stroke Patients. J Neuroimaging. 2017 01; 27(1):59-64. Sanossian N, Fu KA, Liebeskind DS, Starkman S, Hamilton S, Villablanca JP, Burgos AM, Conwit R, Saver JL. PMID: 27300498; PMCID: PMC5156583.
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CLINICAL PRACTICE. Cryptogenic Stroke. N Engl J Med. 2016 May 26; 374(21):2065-74. Saver JL. PMID: 27223148.
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Percutaneous left atrial appendage occlusion: the Munich consensus document on definitions, endpoints and data collection requirements for clinical studies. EuroIntervention. 2016 May 17; 12(1):103-11. Tzikas A, Holmes DR, Gafoor S, Ruiz CE, Blomström-Lundqvist C, Diener HC, Cappato R, Kar S, Lee RJ, Byrne RA, Ibrahim R, Lakkireddy D, Soliman OI, Näbauer M, Schneider S, Brachman J, Saver JL, Tiemann K, Sievert H, Camm AJ, Lewalter T. PMID: 27173870.
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Cost-effectiveness of stent-retriever thrombectomy in combination with IV t-PA compared with IV t-PA alone for acute ischemic stroke in the UK. J Med Econ. 2016 Aug; 19(8):785-94. Lobotesis K, Veltkamp R, Carpenter IH, Claxton LM, Saver JL, Hodgson R. PMID: 27046347.
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Analysis of Workflow and Time to Treatment and the Effects on Outcome in Endovascular Treatment of Acute Ischemic Stroke: Results from the SWIFT PRIME Randomized Controlled Trial. Radiology. 2016 Jun; 279(3):888-97. Goyal M, Jadhav AP, Bonafe A, Diener H, Mendes Pereira V, Levy E, Baxter B, Jovin T, Jahan R, Menon BK, Saver JL, SWIFT PRIME investigators. PMID: 27092472.
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Effect of Treatment Delay, Stroke Type, and Thrombolysis on the Effect of Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome after Acute Stroke: A Systematic Review and Meta-Analysis of Individual Patient from Randomised Trials. Stroke Res Treat. 2016; 2016:9706720. Bath PM, Woodhouse L, Krishnan K, Anderson C, Berge E, Ford GA, Robinson TG, Saver JL, Sprigg N, Wardlaw JM, In Acute Stroke Collaboration Basc BP. PMID: 27190674; PMCID: PMC4852111.
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Association of Get With The Guidelines-Stroke Program Participation and Clinical Outcomes for Medicare Beneficiaries With Ischemic Stroke. Stroke. 2016 05; 47(5):1294-302. Song S, Fonarow GC, Olson DM, Liang L, Schulte PJ, Hernandez AF, Peterson ED, Reeves MJ, Smith EE, Schwamm LH, Saver JL. PMID: 27079809; PMCID: PMC4975426.
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Device Closure of Patent Foramen Ovale After Stroke: Pooled Analysis of Completed Randomized Trials. J Am Coll Cardiol. 2016 Mar 01; 67(8):907-917. Kent DM, Dahabreh IJ, Ruthazer R, Furlan AJ, Reisman M, Carroll JD, Saver JL, Smalling RW, Jüni P, Mattle HP, Meier B, Thaler DE. PMID: 26916479; PMCID: PMC4769377.
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Assessment of Home-Time After Acute Ischemic Stroke in Medicare Beneficiaries. Stroke. 2016 Mar; 47(3):836-42. Fonarow GC, Liang L, Thomas L, Xian Y, Saver JL, Smith EE, Schwamm LH, Peterson ED, Hernandez AF, Duncan PW, O'Brien EC, Bushnell C, Prvu Bettger J. PMID: 26892279.
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Safety and Efficacy of Solitaire Stent Thrombectomy: Individual Patient Data Meta-Analysis of Randomized Trials. Stroke. 2016 Mar; 47(3):798-806. Campbell BC, Hill MD, Rubiera M, Menon BK, Demchuk A, Donnan GA, Roy D, Thornton J, Dorado L, Bonafe A, Levy EI, Diener HC, Hernández-Pérez M, Pereira VM, Blasco J, Quesada H, Rempel J, Jahan R, Davis SM, Stouch BC, Mitchell PJ, Jovin TG, Saver JL, Goyal M. PMID: 26888532; PMCID: PMC4760381.
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Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016 Apr 23; 387(10029):1723-31. Goyal M, Menon BK, van Zwam WH, Dippel DW, Mitchell PJ, Demchuk AM, Dávalos A, Majoie CB, van der Lugt A, de Miquel MA, Donnan GA, Roos YB, Bonafe A, Jahan R, Diener HC, van den Berg LA, Levy EI, Berkhemer OA, Pereira VM, Rempel J, Millán M, Davis SM, Roy D, Thornton J, Román LS, Ribó M, Beumer D, Stouch B, Brown S, Campbell BC, van Oostenbrugge RJ, Saver JL, Hill MD, Jovin TG, HERMES collaborators. PMID: 26898852.
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Warfarin Use and Risk of Stroke in Patients With Atrial Fibrillation Undergoing Hemodialysis: A Meta-Analysis. Medicine (Baltimore). 2016 Feb; 95(6):e2741. Lee M, Saver JL, Hong KS, Wu YL, Huang WH, Rao NM, Ovbiagele B. PMID: 26871818; PMCID: PMC4753914.
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Acute Ischemic Stroke with Very Early Clinical Improvement: A National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trials Exploratory Analysis. J Stroke Cerebrovasc Dis. 2016 Apr; 25(4):894-901. Balucani C, Levine SR, Khoury JC, Khatri P, Saver JL, Broderick JP. PMID: 26825352.
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Effect of endovascular reperfusion in relation to site of arterial occlusion. Neurology. 2016 Feb 23; 86(8):762-70. Lemmens R, Hamilton SA, Liebeskind DS, Tomsick TA, Demchuk AM, Nogueira RG, Marks MP, Jahan R, Gralla J, Yoo AJ, Yeatts SD, Palesch YY, Saver JL, Pereira VM, Broderick JP, Albers GW, Lansberg MG, DEFUSE 2, IMS III, STAR, and SWIFT trialists, DEFUSE 2 IMS III STAR and SWIFT trialists. PMID: 26802090; PMCID: PMC4763803.
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Rigorous anaesthesia management protocol for patients with intracranial arterial stenosis: a prospective controlled-cohort study. BMJ Open. 2016 Jan 19; 6(1):e009727. Laiwalla AN, Ooi YC, Van De Wiele B, Ziv K, Brown A, Liou R, Saver JL, Gonzalez NR. PMID: 26787251; PMCID: PMC4735305.
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What constitutes the M1 segment of the middle cerebral artery? J Neurointerv Surg. 2016 Dec; 8(12):1273-1277. Goyal M, Menon BK, Krings T, Patil S, Qazi E, McTaggart RA, Almekhlafi MA, Jehan R, Saver J, Jayaraman MV. PMID: 26863104.
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Endovascular Therapy in Acute Ischemic Stroke: Challenges and Transition From Trials to Bedside. Stroke. 2016 Feb; 47(2):548-53. Goyal M, Yu AY, Menon BK, Dippel DW, Hacke W, Davis SM, Fisher M, Yavagal DR, Turjman F, Ross J, Yoshimura S, Miao Z, Bhatia R, Almekhlafi M, Murayama Y, Sohn SI, Saver JL, Demchuk AM, Hill MD. PMID: 26742796.
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Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2016 Feb; 47(2):581-641. Demaerschalk BM, Kleindorfer DO, Adeoye OM, Demchuk AM, Fugate JE, Grotta JC, Khalessi AA, Levy EI, Palesch YY, Prabhakaran S, Saposnik G, Saver JL, Smith EE, American Heart Association Stroke Council and Council on Epidemiology and Prevention. PMID: 26696642.
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Challenges and Opportunities of Endovascular Stroke Therapy. Ann Neurol. 2016 Jan; 79(1):11-7. Goyal M, Hill MD, Saver JL, Fisher M. PMID: 26395431.
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Ischemic core and hypoperfusion volumes predict infarct size in SWIFT PRIME. Ann Neurol. 2016 Jan; 79(1):76-89. Albers GW, Goyal M, Jahan R, Bonafe A, Diener HC, Levy EI, Pereira VM, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, de Rochemont Rdu M, Singer OC, Bammer R, Saver JL. PMID: 26476022.
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Impact of Glucose on Outcomes in Patients Treated With Mechanical Thrombectomy: A Post Hoc Analysis of the Solitaire Flow Restoration With the Intention for Thrombectomy Study. Stroke. 2016 Jan; 47(1):120-7. Kim JT, Jahan R, Saver JL, SWIFT Investigators. PMID: 26658447.
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Enrollment Yield and Reasons for Screen Failure in a Large Prehospital Stroke Trial. Stroke. 2016 Jan; 47(1):232-5. Kim DH, Saver JL, Starkman S, Liebeskind DS, Ali LK, Restrepo L, Kim-Tenser M, Valdes-Sueiras M, Eckstein M, Pratt F, Stratton S, Hamilton S, Conwit R, Sanossian N, Field Administration of Stroke Therapy–Magnesium (FAST-MAG) Trial Nurse-Coordinators and Investigato. PMID: 26658446; PMCID: PMC4909489.
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Different Antiplatelet Strategies in Patients With New Ischemic Stroke While Taking Aspirin. Stroke. 2016 Jan; 47(1):128-34. Kim JT, Park MS, Choi KH, Cho KH, Kim BJ, Han MK, Park TH, Park SS, Lee KB, Lee BC, Yu KH, Oh MS, Cha JK, Kim DH, Nah HW, Lee J, Lee SJ, Ko YC, Kim JG, Park JM, Kang K, Cho YJ, Hong KS, Choi JC, Kim DE, Ryu WS, Shin DI, Yeo MJ, Kim WJ, Lee J, Lee JS, Saver JL, Bae HJ. PMID: 26604247.
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New Cerebral Microbleeds After Mechanical Thrombectomy for Large-Vessel Occlusion Strokes. Medicine (Baltimore). 2015 Nov; 94(47):e2180. Shi ZS, Duckwiler GR, Jahan R, Tateshima S, Gonzalez NR, Szeder V, Saver JL, Kim D, Ali LK, Starkman S, Vespa PM, Salamon N, Villablanca JP, Viñuela F, Feng L, Loh Y, Liebeskind DS. PMID: 26632753; PMCID: PMC5059022.
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DWI Lesion Patterns Predict Outcome in Stroke Patients with Thrombolysis. Cerebrovasc Dis. 2015; 40(5-6):279-285. Liu D, Scalzo F, Starkman S, Rao NM, Hinman JD, Kim D, Ali LK, Saver JL, Noorian AR, Ng K, Liang C, Sheth SA, Yoo B, Liu X, Liebeskind DS, UCLA-Jinling Neurovascular Imaging Research Collaborators. PMID: 26513397; PMCID: PMC4955553.
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Variability in Criteria for Emergency Medical Services Routing of Acute Stroke Patients to Designated Stroke Center Hospitals. West J Emerg Med. 2015 Sep; 16(5):743-6. Dimitrov N, Koenig W, Bosson N, Song S, Saver JL, Mack WJ, Sanossian N. PMID: 26587100; PMCID: PMC4644044.
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Early Magnesium Treatment After Aneurysmal Subarachnoid Hemorrhage: Individual Patient Data Meta-Analysis. Stroke. 2015 Nov; 46(11):3190-3. Dorhout Mees SM, Algra A, Wong GK, Poon WS, Bradford CM, Saver JL, Starkman S, Rinkel GJ, van den Bergh WM, writing groups of MASH-I, IMASH, MASH-II, MASH and FAST-MAG, van Kooten F, Dirven CM, van Gijn J, Vermeulen M, Rinkel GJ, Boet R, Chan MT, Gin T, Ng SC, Zee BC, Al-Shahi Salman R, Boiten J, Kuijsten H, Lavados PM, van Oostenbrugge RJ, Vandertop WP, Finfer S, O'Connor A, Yarad E, Firth R, McCallister R, Harrington T, Steinfort B, Faulder K, Assaad N, Morgan M, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N. PMID: 26463689.
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Early Loss of Immediate Reperfusion While Stent Retriever in Place Predicts Successful Final Reperfusion in Acute Ischemic Stroke Patients. Stroke. 2015 Nov; 46(11):3266-9. Okawa M, Tateshima S, Liebeskind D, Rao N, Jahan R, Gonzalez N, Szeder V, Ali L, Kim D, Saver J, Duckwiler G. PMID: 26451013; PMCID: PMC4734750.
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Patient-Centered Decision Support in Acute Ischemic Stroke: Qualitative Study of Patients' and Providers' Perspectives. Circ Cardiovasc Qual Outcomes. 2015 Oct; 8(6 Suppl 3):S109-16. Decker C, Chhatriwalla E, Gialde E, Garavalia B, Summers D, Quinlan ME, Cheng E, Rymer M, Saver JL, Chen E, Kent DM, Spertus JA. PMID: 26515198.
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Quality of Care and Ischemic Stroke Risk After Hospitalization for Transient Ischemic Attack: Findings From Get With The Guidelines-Stroke. Circ Cardiovasc Qual Outcomes. 2015 Oct; 8(6 Suppl 3):S117-24. O'Brien EC, Zhao X, Fonarow GC, Schulte PJ, Dai D, Smith EE, Schwamm LH, Bhatt DL, Xian Y, Saver JL, Reeves MJ, Peterson ED, Hernandez AF. PMID: 26515199.
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Stent-Retriever Thrombectomy for Stroke. N Engl J Med. 2015 09 10; 373(11):1077. Saver JL, Goyal M, Diener HC, SWIFT PRIME Investigators. PMID: 26352820.
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A collaborative sequential meta-analysis of individual patient data from randomized trials of endovascular therapy and tPA vs. tPA alone for acute ischemic stroke: ThRombEctomy And tPA (TREAT) analysis: statistical analysis plan for a sequential meta-analysis performed within the VISTA-Endovascular collaboration. Int J Stroke. 2015 Oct; 10 Suppl A100:136-44. MacIsaac RL, Khatri P, Bendszus M, Bracard S, Broderick J, Campbell B, Ciccone A, Dávalos A, Davis SM, Demchuk A, Diener HC, Dippel D, Donnan GA, Fiehler J, Fiorella D, Goyal M, Hacke W, Hill MD, Jahan R, Jauch E, Jovin T, Kidwell CS, Liebeskind D, Majoie CB, Martins SC, Mitchell P, Mocco J, Muir KW, Nogueira R, Saver JL, Schonewille WJ, Siddiqui AH, Thomalla G, Tomsick TA, Turk AS, White P, Zaidat O, Lees KR, VISTA Endovascular collaboration. PMID: 26352438.
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The Heidelberg Bleeding Classification: Classification of Bleeding Events After Ischemic Stroke and Reperfusion Therapy. Stroke. 2015 Oct; 46(10):2981-6. von Kummer R, Broderick JP, Campbell BC, Demchuk A, Goyal M, Hill MD, Treurniet KM, Majoie CB, Marquering HA, Mazya MV, San Román L, Saver JL, Strbian D, Whiteley W, Hacke W. PMID: 26330447.
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Relationships Between Imaging Assessments and Outcomes in Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke. Stroke. 2015 Oct; 46(10):2786-94. Albers GW, Goyal M, Jahan R, Bonafe A, Diener HC, Levy EI, Pereira VM, Cognard C, Yavagal DR, Saver JL. PMID: 26316344.
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Development and validation of a simplified Stroke-Thrombolytic Predictive Instrument. Neurology. 2015 Sep 15; 85(11):942-9. Kent DM, Ruthazer R, Decker C, Jones PG, Saver JL, Bluhmki E, Spertus JA. PMID: 26291280; PMCID: PMC4567461.
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Time to endovascular reperfusion and degree of disability in acute stroke. Ann Neurol. 2015 Oct; 78(4):584-93. Sheth SA, Jahan R, Gralla J, Pereira VM, Nogueira RG, Levy EI, Zaidat OO, Saver JL, SWIFT-STAR Trialists. PMID: 26153450; PMCID: PMC4955570.
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Racial/Ethnic and Sex Differences in Emergency Medical Services Transport Among Hospitalized US Stroke Patients: Analysis of the National Get With The Guidelines-Stroke Registry. J Am Heart Assoc. 2015 Aug 12; 4(8):e002099. Mochari-Greenberger H, Xian Y, Hellkamp AS, Schulte PJ, Bhatt DL, Fonarow GC, Saver JL, Reeves MJ, Schwamm LH, Smith EE. PMID: 26268882; PMCID: PMC4599467.
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Routing Ambulances to Designated Centers Increases Access to Stroke Center Care and Enrollment in Prehospital Research. Stroke. 2015 Oct; 46(10):2886-90. Sanossian N, Liebeskind DS, Eckstein M, Starkman S, Stratton S, Pratt FD, Koenig W, Hamilton S, Kim-Tenser M, Conwit R, Saver JL, FAST-MAG Investigators and Coordinators. PMID: 26265130; PMCID: PMC4920547.
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Clinical Implications of Changes in Individual Platelet Reactivity to Aspirin Over Time in Acute Ischemic Stroke. Stroke. 2015 Sep; 46(9):2534-40. Kim JT, Heo SH, Choi KH, Nam TS, Choi SM, Lee SH, Park MS, Kim BC, Kim MK, Saver JL, Cho KH. PMID: 26219647.
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Adopting a Patient-Centered Approach to Primary Outcome Analysis of Acute Stroke Trials Using a Utility-Weighted Modified Rankin Scale. Stroke. 2015 Aug; 46(8):2238-43. Chaisinanunkul N, Adeoye O, Lewis RJ, Grotta JC, Broderick J, Jovin TG, Nogueira RG, Elm JJ, Graves T, Berry S, Lees KR, Barreto AD, Saver JL, DAWN Trial and MOST Trial Steering Committees, Additional contributors from DAWN Trial Steering Committee. PMID: 26138130; PMCID: PMC4519373.
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Future directions of acute ischaemic stroke therapy. Lancet Neurol. 2015 Jul; 14(7):758-67. Fisher M, Saver JL. PMID: 26067128.
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Endovascular stent thrombectomy: the new standard of care for large vessel ischaemic stroke. Lancet Neurol. 2015 Aug; 14(8):846-854. Campbell BCV, Donnan GA, Lees KR, Hacke W, Khatri P, Hill MD, Goyal M, Mitchell PJ, Saver JL, Diener HC, Davis SM. PMID: 26119323.
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Proposed methodology and classification of Infarct in New Territory (INT) after endovascular stroke treatment. J Neurointerv Surg. 2017 May; 9(5):449-450. Goyal M, Menon BK, Demchuk A, Saver JL, Eesa M, Majoie C, Jayaraman M, Hill MD. PMID: 26080828.
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Encephaloduroarteriosynangiosis for adult intracranial arterial steno-occlusive disease: long-term single-center experience with 107 operations. J Neurosurg. 2015 Sep; 123(3):654-61. Gonzalez NR, Dusick JR, Connolly M, Bounni F, Martin NA, Van de Wiele B, Liebeskind DS, Saver JL. PMID: 26067617.
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Imaging in StrokeNet: Realizing the Potential of Big Data. Stroke. 2015 Jul; 46(7):2000-6. Liebeskind DS, Albers GW, Crawford K, Derdeyn CP, George MS, Palesch YY, Toga AW, Warach S, Zhao W, Brott TG, Sacco RL, Khatri P, Saver JL, Cramer SC, Wolf SL, Broderick JP, Wintermark M. PMID: 26045600; PMCID: PMC4557967.
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Effect of Blood Pressure Lowering in Early Ischemic Stroke: Meta-Analysis. Stroke. 2015 Jul; 46(7):1883-9. Lee M, Ovbiagele B, Hong KS, Wu YL, Lee JE, Rao NM, Feng W, Saver JL. PMID: 26022636.
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Mechanical thrombectomy for acute ischemic stroke with cerebral microbleeds. J Neurointerv Surg. 2016 Jun; 8(6):563-7. Shi ZS, Duckwiler GR, Jahan R, Tateshima S, Gonzalez NR, Szeder V, Saver JL, Kim D, Ali LK, Starkman S, Vespa PM, Salamon N, Villablanca JP, Viñuela F, Feng L, Loh Y, Liebeskind DS. PMID: 25994939.
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Evaluation of the JRecan device for thrombus retrieval: efficacy and safety in a swine model of acute arterial occlusion. J Neurointerv Surg. 2016 May; 8(5):526-30. Zhu L, Shao Q, Li T, Saver JL, Li L, Li D, Zhao W, Jiang W. PMID: 25994941.
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Early arrival at the emergency department is associated with better collaterals, smaller established infarcts and better clinical outcomes with endovascular stroke therapy: SWIFT study. J Neurointerv Surg. 2016 Jun; 8(6):553-8. Liebeskind DS, Jahan R, Nogueira RG, Jovin TG, Lutsep HL, Saver JL, SWIFT Investigators. PMID: 25964375.
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State of acute endovascular therapy: report from the 12th thrombolysis, thrombectomy, and acute stroke therapy conference. Stroke. 2015 Jun; 46(6):1727-34. Khatri P, Hacke W, Fiehler J, Saver JL, Diener HC, Bendszus M, Bracard S, Broderick J, Campbell B, Ciccone A, Dávalos A, Davis S, Demchuk AM, Dippel D, Donnan G, Fiorella D, Goyal M, Hill MD, Jauch EC, Jovin TG, Kidwell CS, Majoie C, Martins SC, Mitchell P, Mocco J, Muir K, Nogueira RG, Schonewille WJ, Siddiqui AH, Thomalla G, Tomsick TA, Turk AS, White PM, Zaidat OO, Liebeskind DS, Fulton R, Lees KR, VISTA-Endovascular Collaboration. PMID: 25944325.
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Clinical outcomes of patients with acute minor stroke receiving rescue IA therapy following early neurological deterioration. J Neurointerv Surg. 2016 May; 8(5):461-5. Kim JT, Heo SH, Yoon W, Choi KH, Park MS, Saver JL, Cho KH. PMID: 25910943.
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Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015 Jun 11; 372(24):2285-95. Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, du Mesnil de Rochemont R, Singer OC, Jahan R, SWIFT PRIME Investigators. PMID: 25882376.
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Solitaire™ with the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) trial: protocol for a randomized, controlled, multicenter study comparing the Solitaire revascularization device with IV tPA with IV tPA alone in acute ischemic stroke. Int J Stroke. 2015 Apr; 10(3):439-48. Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Devlin TG, Lopes DK, Reddy V, du Mesnil de Rochemont R, Jahan R, SWIFT PRIME Investigators. PMID: 25777831; PMCID: PMC4405096.
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Postischemic hyperperfusion on arterial spin labeled perfusion MRI is linked to hemorrhagic transformation in stroke. J Cereb Blood Flow Metab. 2015 Mar 31; 35(4):630-7. Yu S, Liebeskind DS, Dua S, Wilhalme H, Elashoff D, Qiao XJ, Alger JR, Sanossian N, Starkman S, Ali LK, Scalzo F, Lou X, Yoo B, Saver JL, Salamon N, Wang DJ, UCLA Stroke Investigators. PMID: 25564233; PMCID: PMC4420881.
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Intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015 03 19; 372(12):1177. Sheth SA, Saver JL, Starkman S. PMID: 25785981.
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Letter by Saver et al regarding article, "Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association". Stroke. 2015 Apr; 46(4):e85-6. Saver JL, Carroll JD, Smalling R, Thaler D. PMID: 25744518.
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Enrollment bias: frequency and impact on patient selection in endovascular stroke trials. J Neurointerv Surg. 2016 Apr; 8(4):353-9. Sheth SA, Saver JL, Starkman S, Grunberg ID, Guzy J, Ali LK, Kim D, Gonzalez NR, Jahan R, Tateshima S, Duckwiler G, Liebeskind DS. PMID: 25700030; PMCID: PMC4544665.
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Trends in endovascular therapy and clinical outcomes within the nationwide Get With The Guidelines-Stroke registry. Stroke. 2015 Apr; 46(4):989-95. Menon BK, Saver JL, Goyal M, Nogueira R, Prabhakaran S, Liang L, Xian Y, Hernandez AF, Fonarow GC, Schwamm L, Smith EE. PMID: 25681065.
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Rapid learning curve for Solitaire FR stent retriever therapy: evidence from roll-in and randomised patients in the SWIFT trial. J Neurointerv Surg. 2016 Apr; 8(4):347-52. Sheth SA, Jahan R, Levy EI, Jovin TG, Baxter B, Nogueira RG, Clark W, Budzik R, Zaidat OO, Saver JL, SWIFT Trialists. PMID: 25676147; PMCID: PMC4955564.
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Noninvasive Qureshi Grading Scheme Predicts 90-Day mRS in Patients with Acute Ischemic Stroke. J Neuroimaging. 2015 Sep-Oct; 25(5):761-5. Shin DI, Lee HS, Baek SH, Lee SS, Lee SH, Saver JL, Liebeskind DS. PMID: 25684593.
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Prehospital use of magnesium sulfate as neuroprotection in acute stroke. N Engl J Med. 2015 Feb 05; 372(6):528-36. Saver JL, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N, FAST-MAG Investigators and Coordinators. PMID: 25651247; PMCID: PMC4920545.
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Response to letter regarding article, "defining clinically relevant cerebral hemorrhage after thrombolytic therapy for stroke: analysis of the national institute of neurological disorders and stroke tissue-type plasminogen activator trials". Stroke. 2015 Feb; 46(2):e45. Rao NM, Levine SR, Saver JL. PMID: 25572410.
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Discharge destination after acute hospitalization strongly predicts three month disability outcome in ischemic stroke. Restor Neurol Neurosci. 2015; 33(5):771-5. Zhang Q, Yang Y, Saver JL. PMID: 26410209.
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Successful recanalization for acute ischemic stroke via the transbrachial approach. J Neurointerv Surg. 2016 Feb; 8(2):122-5. Okawa M, Tateshima S, Liebeskind D, Ali LK, Thompson ML, Saver J, Duckwiler GR. PMID: 25471073.
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Is clopidogrel better than aspirin following breakthrough strokes while on aspirin? A retrospective cohort study. BMJ Open. 2014 Dec 02; 4(12):e006672. Lee M, Wu YL, Saver JL, Lee HC, Lee JD, Chang KC, Wu CY, Lee TH, Wang HH, Rao NM, Ovbiagele B. PMID: 25468508; PMCID: PMC4256539.
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Initial body temperature in ischemic stroke: nonpotentiation of tissue-type plasminogen activator benefit and inverse association with severity. Stroke. 2015 Jan; 46(1):132-6. Kim SH, Saver JL. PMID: 25424482; PMCID: PMC4300232.
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Hospital and demographic characteristics associated with advanced primary stroke center designation. Stroke. 2014 Dec; 45(12):3717-9. McDonald CM, Cen S, Ramirez L, Song S, Saver JL, Mack WJ, Sanossian N. PMID: 25388418.
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Collateral flow as causative of good outcomes in endovascular stroke therapy. J Neurointerv Surg. 2016 Jan; 8(1):2-7. Sheth SA, Sanossian N, Hao Q, Starkman S, Ali LK, Kim D, Gonzalez NR, Tateshima S, Jahan R, Duckwiler GR, Saver JL, Vinuela F, Liebeskind DS, UCLA Collateral Investigators. PMID: 25378639; PMCID: PMC4468030.
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Clinical performance measures for adults hospitalized with acute ischemic stroke: performance measures for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014 Nov; 45(11):3472-98. Smith EE, Saver JL, Alexander DN, Furie KL, Hopkins LN, Katzan IL, Mackey JS, Miller EL, Schwamm LH, Williams LS, AHA/ASA Stroke Performance Oversight Committee. PMID: 25256184.
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Chronic kidney disease and bleeding complications after intravenous thrombolytic therapy for acute ischemic stroke. Circ Cardiovasc Qual Outcomes. 2014 Nov; 7(6):929-35. Ovbiagele B, Smith EE, Schwamm LH, Grau-Sepulveda MV, Saver JL, Bhatt DL, Hernandez AF, Peterson ED, Fonarow GC. PMID: 25249561.
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Challenges of acute endovascular stroke trials. Stroke. 2014 Oct; 45(10):3116-22. Goyal M, Almekhlafi M, Menon B, Hill M, Fargen K, Parsons M, Bang OY, Siddiqui A, Andersson T, Mendes V, Davalos A, Turk A, Mocco J, Campbell B, Nogueira R, Gupta R, Murphy S, Jovin T, Khatri P, Miao Z, Demchuk A, Broderick JP, Saver J. PMID: 25169945.
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Cognitive impairment and risk of future stroke: a systematic review and meta-analysis. CMAJ. 2014 Oct 07; 186(14):E536-46. Lee M, Saver JL, Hong KS, Wu YL, Liu HC, Rao NM, Ovbiagele B. PMID: 25157064; PMCID: PMC4188684.
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Hospitalized hemorrhagic stroke patients with renal insufficiency: clinical characteristics, care patterns, and outcomes. J Stroke Cerebrovasc Dis. 2014 Oct; 23(9):2265-73. Ovbiagele B, Schwamm LH, Smith EE, Grau-Sepulveda MV, Saver JL, Bhatt DL, Hernandez AF, Peterson ED, Fonarow GC. PMID: 25158677.
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Defining clinically relevant cerebral hemorrhage after thrombolytic therapy for stroke: analysis of the National Institute of Neurological Disorders and Stroke tissue-type plasminogen activator trials. Stroke. 2014 Sep; 45(9):2728-33. Rao NM, Levine SR, Gornbein JA, Saver JL. PMID: 25096731; PMCID: PMC4154062.
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Predictors and Outcomes Associated with Rescue Therapy in SWIFT. Interv Neurol. 2014 Aug; 2(4):178-82. Lazzaro MA, Zaidat OO, Saver JL, SWIFT investigators. PMID: 25337086; PMCID: PMC4188160.
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Testing devices for the prevention and treatment of stroke and its complications. Int J Stroke. 2014 Aug; 9(6):683-95. Bath PM, Brainin M, Brown C, Campbell B, Davis SM, Donnan GA, Ford GA, Hacke W, Iglesias C, Lees KR, Pugh SS, Saver JL, Schellinger PD, Truelsen T. PMID: 25043517.
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Computed Tomography Angiography in the Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Study. Interv Neurol. 2014 Aug; 2(4):153-9. Liebeskind DS, Kosinski AS, Saver JL, Feldmann E, SONIA Investigators. PMID: 25337084; PMCID: PMC4188162.
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Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically verified Alzheimer disease. JAMA Neurol. 2014 Jul 01; 71(7):878-83. Ringman JM, Sachs MC, Zhou Y, Monsell SE, Saver JL, Vinters HV. PMID: 24797962; PMCID: PMC4101018.
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Expansion of U.S. emergency medical service routing for stroke care: 2000-2010. West J Emerg Med. 2014 Jul; 15(4):499-503. Hanks N, Wen G, He S, Song S, Saver JL, Cen S, Kim-Tenser M, Mack W, Sanossian N. PMID: 25035758; PMCID: PMC4100858.
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Patterns of care quality and prognosis among hospitalized ischemic stroke patients with chronic kidney disease. J Am Heart Assoc. 2014 Jun 05; 3(3):e000905. Ovbiagele B, Schwamm LH, Smith EE, Grau-Sepulveda MV, Saver JL, Bhatt DL, Hernandez AF, Peterson ED, Fonarow GC. PMID: 24904017; PMCID: PMC4309090.
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Impact of collaterals on successful revascularization in Solitaire FR with the intention for thrombectomy. Stroke. 2014 Jul; 45(7):2036-40. Liebeskind DS, Jahan R, Nogueira RG, Zaidat OO, Saver JL, SWIFT Investigators. PMID: 24876081; PMCID: PMC4157911.
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The THRIVE score strongly predicts outcomes in patients treated with the Solitaire device in the SWIFT and STAR trials. Int J Stroke. 2014 Aug; 9(6):698-704. Flint AC, Cullen SP, Rao VA, Faigeles BS, Pereira VM, Levy EI, Jovin TG, Liebeskind DS, Nogueira RG, Jahan R, Saver JL, SWIFT and STAR trialists. PMID: 24844862; PMCID: PMC4160885.
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M2 occlusions as targets for endovascular therapy: comprehensive analysis of diffusion/perfusion MRI, angiography, and clinical outcomes. J Neurointerv Surg. 2015 Jul; 7(7):478-83. Sheth SA, Yoo B, Saver JL, Starkman S, Ali LK, Kim D, Gonzalez NR, Jahan R, Tateshima S, Duckwiler G, Vinuela F, Liebeskind DS, UCLA Comprehensive Stroke Center. PMID: 24821842; PMCID: PMC4229477.
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Magnesium: potential roles in neurovascular disease. Front Neurol. 2014; 5:52. Chang JJ, Mack WJ, Saver JL, Sanossian N. PMID: 24782823; PMCID: PMC3995053.
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Strategies used by hospitals to improve speed of tissue-type plasminogen activator treatment in acute ischemic stroke. Stroke. 2014 May; 45(5):1387-95. Xian Y, Smith EE, Zhao X, Peterson ED, Olson DM, Hernandez AF, Bhatt DL, Saver JL, Schwamm LH, Fonarow GC. PMID: 24713527.
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Door-to-needle times for tissue plasminogen activator administration and clinical outcomes in acute ischemic stroke before and after a quality improvement initiative. JAMA. 2014 Apr 23-30; 311(16):1632-40. Fonarow GC, Zhao X, Smith EE, Saver JL, Reeves MJ, Bhatt DL, Xian Y, Hernandez AF, Peterson ED, Schwamm LH. PMID: 24756513.
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Advancing neurotherapeutics in the 21st century. JAMA. 2014 Apr 23-30; 311(16):1620-1. Rosenberg RN, Saver JL. PMID: 24756511; PMCID: PMC6764516.
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Stroke thrombolysis: save a minute, save a day. Stroke. 2014 Apr; 45(4):1053-8. Meretoja A, Keshtkaran M, Saver JL, Tatlisumak T, Parsons MW, Kaste M, Davis SM, Donnan GA, Churilov L. PMID: 24627114.
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Serial Alberta Stroke Program early CT score from baseline to 24 hours in Solitaire Flow Restoration with the Intention for Thrombectomy study: a novel surrogate end point for revascularization in acute stroke. Stroke. 2014 Mar; 45(3):723-7. Liebeskind DS, Jahan R, Nogueira RG, Jovin TG, Lutsep HL, Saver JL, SWIFT Investigators. PMID: 24525954; PMCID: PMC3952017.
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Stroke outcomes measures must be appropriately risk adjusted to ensure quality care of patients: a presidential advisory from the American Heart Association/American Stroke Association. Stroke. 2014 May; 45(5):1589-601. Fonarow GC, Alberts MJ, Broderick JP, Jauch EC, Kleindorfer DO, Saver JL, Solis P, Suter R, Schwamm LH. PMID: 24523036.
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Blood pressure management in early ischemic stroke. JAMA. 2014 Feb 05; 311(5):469-70. Saver JL. PMID: 24496534.
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Methodology of the Field Administration of Stroke Therapy - Magnesium (FAST-MAG) phase 3 trial: Part 2 - prehospital study methods. Int J Stroke. 2014 Feb; 9(2):220-5. Saver JL, Starkman S, Eckstein M, Stratton S, Pratt F, Hamilton S, Conwit R, Liebeskind DS, Sung G, Sanossian N, FAST-MAG Investigators and Coordinators. PMID: 24444117; PMCID: PMC4909491.
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Symptomatic intracranial hemorrhage after stroke thrombolysis: comparison of prediction scores. Stroke. 2014 Mar; 45(3):752-8. Strbian D, Michel P, Seiffge DJ, Saver JL, Numminen H, Meretoja A, Murao K, Weder B, Forss N, Parkkila AK, Eskandari A, Cordonnier C, Davis SM, Engelter ST, Tatlisumak T. PMID: 24473180.
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Role of statin in atrial fibrillation-related stroke: an angiographic study for collateral flow. Cerebrovasc Dis. 2014; 37(2):77-84. Lee MJ, Bang OY, Kim SJ, Kim GM, Chung CS, Lee KH, Ovbiagele B, Liebeskind DS, Saver JL. PMID: 24457535; PMCID: PMC4157914.
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Methodology of the Field Administration of Stroke Therapy - Magnesium (FAST-MAG) phase 3 trial: Part 1 - rationale and general methods. Int J Stroke. 2014 Feb; 9(2):215-9. Saver JL, Starkman S, Eckstein M, Stratton S, Pratt F, Hamilton S, Conwit R, Liebeskind DS, Sung G, Sanossian N, FAST-MAG Investigators and Coordinators. PMID: 24444116; PMCID: PMC4915821.
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Endovascular stroke trials: why we must enroll all eligible patients. Stroke. 2013 Dec; 44(12):3591-5. Goyal M, Shamy M, Menon BK, Saver JL, Diener HC, Mocco J, Pereira VM, Jovin TG, Zaidat O, Levy EI, Davalos A, Demchuk A, Hill MD. PMID: 24222044.
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Acute ischemic stroke and timing of treatment--reply. JAMA. 2013 Nov 06; 310(17):1856-7. Saver JL, Fonarow GC, Schwamm LH. PMID: 24193086.
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Stroke treatment academic industry roundtable: research priorities in the assessment of neurothrombectomy devices. Stroke. 2013 Dec; 44(12):3596-601. Saver JL, Jovin TG, Smith WS, Albers GW, Baron JC, Boltze J, Broderick JP, Davis LA, Demchuk AM, DeSena S, Fiehler J, Gorelick PB, Hacke W, Holt B, Jahan R, Jing H, Khatri P, Kidwell CS, Lees KR, Lev MH, Liebeskind DS, Luby M, Lyden P, Megerian JT, Mocco J, Muir KW, Rowley HA, Ruedy RM, Savitz SI, Sipelis VJ, Shimp SK, Wechsler LR, Wintermark M, Wu O, Yavagal DR, Yoo AJ, STAIR VIII Consortium. PMID: 24193797; PMCID: PMC4142766.
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Comparison of performance achievement award recognition with primary stroke center certification for acute ischemic stroke care. J Am Heart Assoc. 2013 Oct 14; 2(5):e000451. Fonarow GC, Liang L, Smith EE, Reeves MJ, Saver JL, Xian Y, Hernandez AF, Peterson ED, Schwamm LH, GWTG-Stroke Steering Committee & Investigators. PMID: 24125846; PMCID: PMC3835260.
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Impact of emergency medical services stroke routing protocols on Primary Stroke Center certification in California. Stroke. 2013 Dec; 44(12):3584-6. Schuberg S, Song S, Saver JL, Mack WJ, Cen SY, Sanossian N. PMID: 24105701.
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Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis. Ann Intern Med. 2013 Oct 01; 159(7):463-70. Lee M, Saver JL, Hong KS, Rao NM, Wu YL, Ovbiagele B. PMID: 24081287.
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Successful treatment of extensive cerebral venous sinus thrombosis using a combined approach with Penumbra aspiration system and Solitaire FR retrieval device. J Neurointerv Surg. 2014 Jun; 6(5):e32. Raychev R, Tateshima S, Rastogi S, Balgude A, Yafeh B, Saver JL, Vespa PM, Buitrago M, Duckwiler G. PMID: 24049112.
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Successful treatment of extensive cerebral venous sinus thrombosis using a combined approach with Penumbra aspiration system and Solitaire FR retrieval device. BMJ Case Rep. 2013 Sep 10; 2013. Raychev R, Tateshima S, Rastogi S, Balgude A, Yafeh B, Saver JL, Vespa PM, Buitrago M, Duckwiler G. PMID: 24022899; PMCID: PMC3794141.
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Temporal trends in patient characteristics and treatment with intravenous thrombolysis among acute ischemic stroke patients at Get With The Guidelines-Stroke hospitals. Circ Cardiovasc Qual Outcomes. 2013 Sep 01; 6(5):543-9. Schwamm LH, Ali SF, Reeves MJ, Smith EE, Saver JL, Messe S, Bhatt DL, Grau-Sepulveda MV, Peterson ED, Fonarow GC. PMID: 24046398.
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Interactions within stroke systems of care: a policy statement from the American Heart Association/American Stroke Association. Stroke. 2013 Oct; 44(10):2961-84. Higashida R, Alberts MJ, Alexander DN, Crocco TJ, Demaerschalk BM, Derdeyn CP, Goldstein LB, Jauch EC, Mayer SA, Meltzer NM, Peterson ED, Rosenwasser RH, Saver JL, Schwamm L, Summers D, Wechsler L, Wood JP, American Heart Association Advocacy Coordinating Committee. PMID: 23988638.
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Granulocyte colony-stimulating factor in patients with acute ischemic stroke: results of the AX200 for Ischemic Stroke trial. Stroke. 2013 Oct; 44(10):2681-7. Ringelstein EB, Thijs V, Norrving B, Chamorro A, Aichner F, Grond M, Saver J, Laage R, Schneider A, Rathgeb F, Vogt G, Charissé G, Fiebach JB, Schwab S, Schäbitz WR, Kollmar R, Fisher M, Brozman M, Skoloudik D, Gruber F, Serena Leal J, Veltkamp R, Köhrmann M, Berrouschot J, AXIS 2 Investigators. PMID: 23963331.
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Optimizing prediction scores for poor outcome after intra-arterial therapy in anterior circulation acute ischemic stroke. Stroke. 2013 Dec; 44(12):3324-30. Sarraj A, Albright K, Barreto AD, Boehme AK, Sitton CW, Choi J, Lutzker SL, Sun CH, Bibars W, Nguyen CB, Mir O, Vahidy F, Wu TC, Lopez GA, Gonzales NR, Edgell R, Martin-Schild S, Hallevi H, Chen PR, Dannenbaum M, Saver JL, Liebeskind DS, Nogueira RG, Gupta R, Grotta JC, Savitz SI. PMID: 23929748; PMCID: PMC4135710.
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Peripheral vascular disease as remote ischemic preconditioning, for acute stroke. Clin Neurol Neurosurg. 2013 Oct; 115(10):2124-9. Connolly M, Bilgin-Freiert A, Ellingson B, Dusick JR, Liebeskind D, Saver J, Gonzalez NR. PMID: 23958050; PMCID: PMC3798063.
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Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke. 2013 Sep; 44(9):2650-63. Zaidat OO, Yoo AJ, Khatri P, Tomsick TA, von Kummer R, Saver JL, Marks MP, Prabhakaran S, Kallmes DF, Fitzsimmons BF, Mocco J, Wardlaw JM, Barnwell SL, Jovin TG, Linfante I, Siddiqui AH, Alexander MJ, Hirsch JA, Wintermark M, Albers G, Woo HH, Heck DV, Lev M, Aviv R, Hacke W, Warach S, Broderick J, Derdeyn CP, Furlan A, Nogueira RG, Yavagal DR, Goyal M, Demchuk AM, Bendszus M, Liebeskind DS, Cerebral Angiographic Revascularization Grading (CARG) Collaborators, STIR Revascularization working group, STIR Thrombolysis in Cerebral Infarction (TICI) Task Force. PMID: 23920012; PMCID: PMC4160883.
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Reduction in early stroke risk in carotid stenosis with transient ischemic attack associated with statin treatment. Stroke. 2013 Oct; 44(10):2814-20. Merwick Á, Albers GW, Arsava EM, Ay H, Calvet D, Coutts SB, Cucchiara BL, Demchuk AM, Giles MF, Mas JL, Olivot JM, Purroy F, Rothwell PM, Saver JL, Sharma VK, Tsivgoulis G, Kelly PJ. PMID: 23908061; PMCID: PMC3871879.
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Drip, Ship, and Grip, then Slice and Dice: Comprehensive Stroke Center Management of Cervical and Intracranial Emboli. Front Neurol. 2013; 4:104. Hinman JD, Rao NM, Yallapragada A, Capri J, Souda P, Whitelegge J, Yong WH, Jahan R, Quinones-Baldrich W, Saver JL. PMID: 23908644; PMCID: PMC3725951.
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Acute Stroke Imaging Research Roadmap II. Stroke. 2013 Sep; 44(9):2628-39. Wintermark M, Albers GW, Broderick JP, Demchuk AM, Fiebach JB, Fiehler J, Grotta JC, Houser G, Jovin TG, Lees KR, Lev MH, Liebeskind DS, Luby M, Muir KW, Parsons MW, von Kummer R, Wardlaw JM, Wu O, Yoo AJ, Alexandrov AV, Alger JR, Aviv RI, Bammer R, Baron JC, Calamante F, Campbell BC, Carpenter TC, Christensen S, Copen WA, Derdeyn CP, Haley EC, Khatri P, Kudo K, Lansberg MG, Latour LL, Lee TY, Leigh R, Lin W, Lyden P, Mair G, Menon BK, Michel P, Mikulik R, Nogueira RG, Ostergaard L, Pedraza S, Riedel CH, Rowley HA, Sanelli PC, Sasaki M, Saver JL, Schaefer PW, Schellinger PD, Tsivgoulis G, Wechsler LR, White PM, Zaharchuk G, Zaidat OO, Davis SM, Donnan GA, Furlan AJ, Hacke W, Kang DW, Kidwell C, Thijs VN, Thomalla G, Warach SJ, Stroke Imaging Research (STIR) and Virtual International Stroke Trials Archive (VISTA)-Imaging Inves. PMID: 23860298; PMCID: PMC4040226.
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Multi-delay multi-parametric arterial spin-labeled perfusion MRI in acute ischemic stroke - Comparison with dynamic susceptibility contrast enhanced perfusion imaging. Neuroimage Clin. 2013; 3:1-7. Wang DJ, Alger JR, Qiao JX, Gunther M, Pope WB, Saver JL, Salamon N, Liebeskind DS, UCLA Stroke Investigators. PMID: 24159561; PMCID: PMC3791289.
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Patent foramen ovale and cryptogenic stroke. N Engl J Med. 2013 07 04; 369(1):91-2. Carroll JD, Saver JL, Steering Committee of the RESPECT Investigators. PMID: 23833784.
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Prehospital stroke care: new prospects for treatment and clinical research. Neurology. 2013 Jul 30; 81(5):501-8. Audebert HJ, Saver JL, Starkman S, Lees KR, Endres M. PMID: 23897876; PMCID: PMC3776535.
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Endovascular treatment for acute ischemic stroke. N Engl J Med. 2013 06 20; 368(25):2434-5. Kidwell CS, Jahan R, Saver JL. PMID: 23802241.
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Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke. JAMA. 2013 Jun 19; 309(23):2480-8. Saver JL, Fonarow GC, Smith EE, Reeves MJ, Grau-Sepulveda MV, Pan W, Olson DM, Hernandez AF, Peterson ED, Schwamm LH. PMID: 23780461.
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The evolution of technology. Stroke. 2013 Jun; 44(6 Suppl 1):S13-5. Saver JL. PMID: 23709710; PMCID: PMC3777260.
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Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association. Stroke. 2013 Aug; 44(8):2361-75. Ovbiagele B, Goldstein LB, Higashida RT, Howard VJ, Johnston SC, Khavjou OA, Lackland DT, Lichtman JH, Mohl S, Sacco RL, Saver JL, Trogdon JG, American Heart Association Advocacy Coordinating Committee and Stroke Council. PMID: 23697546.
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Patterns of emergency medical services use and its association with timely stroke treatment: findings from Get With the Guidelines-Stroke. Circ Cardiovasc Qual Outcomes. 2013 May 01; 6(3):262-9. Ekundayo OJ, Saver JL, Fonarow GC, Schwamm LH, Xian Y, Zhao X, Hernandez AF, Peterson ED, Cheng EM. PMID: 23633218.
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Multi-center prediction of hemorrhagic transformation in acute ischemic stroke using permeability imaging features. Magn Reson Imaging. 2013 Jul; 31(6):961-9. Scalzo F, Alger JR, Hu X, Saver JL, Dani KA, Muir KW, Demchuk AM, Coutts SB, Luby M, Warach S, Liebeskind DS, STIR/VISTA Imaging Investigators. PMID: 23587928; PMCID: PMC3676704.
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Stroke in primary hyperoxaluria type I. J Neuroimaging. 2014 Jul-Aug; 24(4):411-3. Rao NM, Yallapragada A, Winden KD, Saver J, Liebeskind DS. PMID: 23551880; PMCID: PMC4156598.
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Closure of patent foramen ovale versus medical therapy after cryptogenic stroke. N Engl J Med. 2013 Mar 21; 368(12):1092-100. Carroll JD, Saver JL, Thaler DE, Smalling RW, Berry S, MacDonald LA, Marks DS, Tirschwell DL, RESPECT Investigators. PMID: 23514286.
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Lipid profile, lipid-lowering medications, and intracerebral hemorrhage after tPA in get with the guidelines-stroke. Stroke. 2013 May; 44(5):1354-9. Messé SR, Pervez MA, Smith EE, Siddique KA, Hellkamp AS, Saver JL, Bhatt DL, Fonarow GC, Peterson ED, Schwamm LH. PMID: 23493734.
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A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med. 2013 Mar 07; 368(10):914-23. Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z, Feng L, Meyer BC, Olson S, Schwamm LH, Yoo AJ, Marshall RS, Meyers PM, Yavagal DR, Wintermark M, Guzy J, Starkman S, Saver JL, MR RESCUE Investigators. PMID: 23394476; PMCID: PMC3690785.
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Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013 Mar; 44(3):870-947. Jauch EC, Saver JL, Adams HP, Bruno A, Connors JJ, Demaerschalk BM, Khatri P, McMullan PW, Qureshi AI, Rosenfield K, Scott PA, Summers DR, Wang DZ, Wintermark M, Yonas H, American Heart Association Stroke Council, Council on Cardiovascular Nursing, Council on Peripheral Vascular Disease, Council on Clinical Cardiology. PMID: 23370205.
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A risk score for in-hospital death in patients admitted with ischemic or hemorrhagic stroke. J Am Heart Assoc. 2013 Jan 28; 2(1):e005207. Smith EE, Shobha N, Dai D, Olson DM, Reeves MJ, Saver JL, Hernandez AF, Peterson ED, Fonarow GC, Schwamm LH. PMID: 23525444; PMCID: PMC3603253.
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Thrombolysis in the developing world: is there a role for streptokinase? Int J Stroke. 2013 Oct; 8(7):560-5. Butcher K, Shuaib A, Saver J, Donnan G, Davis SM, Norrving B, Wong KS, Abd-Allah F, Bhatia R, Khan A. PMID: 23336290.
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Dysphagia screening and hospital-acquired pneumonia in patients with acute ischemic stroke: findings from Get with the Guidelines--Stroke. J Stroke Cerebrovasc Dis. 2013 Nov; 22(8):e301-9. Masrur S, Smith EE, Saver JL, Reeves MJ, Bhatt DL, Zhao X, Olson D, Pan W, Hernandez AF, Fonarow GC, Schwamm LH. PMID: 23305674.
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Importance of proper patient selection and endpoint selection in evaluation of new therapies in acute stroke: further analysis of the SENTIS trial. J Neurointerv Surg. 2013 May; 5 Suppl 1:i21-4. Shuaib A, Schwab S, Rutledge JN, Starkman S, Liebeskind DS, Bernardini GL, Boulos A, Abou-Chebl A, Huang DY, Vanhooren G, Cruz-Flores S, Klucznik RP, Saver JL, SENTIS trial investigators. PMID: 23291425; PMCID: PMC4156599.
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Unifying acute stroke treatment guidelines for a Bayesian belief network. Stud Health Technol Inform. 2013; 192:1012. Love A, Arnold CW, El-Saden S, Liebeskind DS, Andrada L, Saver J, Bui AA. PMID: 23920786.
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Risk-benefit profile of warfarin versus aspirin in patients with heart failure and sinus rhythm: a meta-analysis. Circ Heart Fail. 2013 Mar; 6(2):287-92. Lee M, Saver JL, Hong KS, Wu HC, Ovbiagele B. PMID: 23264446.
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The 2012 Feinberg Lecture: treatment swift and treatment sure. Stroke. 2013 Jan; 44(1):270-7. Saver JL. PMID: 23238857; PMCID: PMC3529974.
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Multiparametric MRI and CT models of infarct core and favorable penumbral imaging patterns in acute ischemic stroke. Stroke. 2013 Jan; 44(1):73-9. Kidwell CS, Wintermark M, De Silva DA, Schaewe TJ, Jahan R, Starkman S, Jovin T, Hom J, Jumaa M, Schreier J, Gornbein J, Liebeskind DS, Alger JR, Saver JL. PMID: 23233383; PMCID: PMC3558033.
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Evolution of reperfusion therapies for acute brain and acute myocardial ischemia: a systematic, comparative analysis. Stroke. 2013 Jan; 44(1):94-8. Patel RD, Saver JL. PMID: 23192757.
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Risk of intracranial hemorrhage with protease-activated receptor-1 antagonists. Stroke. 2012 Dec; 43(12):3189-95. Lee M, Saver JL, Hong KS, Wu HC, Ovbiagele B. PMID: 23160882.
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Intracranial arterial stenoses: current viewpoints, novel approaches, and surgical perspectives. Neurosurg Rev. 2013 Apr; 36(2):175-84; discussion 184-5. Gonzalez NR, Liebeskind DS, Dusick JR, Mayor F, Saver J. PMID: 23097149; PMCID: PMC3929590.
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Developing practice recommendations for endovascular revascularization for acute ischemic stroke. Neurology. 2012 Sep 25; 79(13 Suppl 1):S243-55. Lazzaro MA, Novakovic RL, Alexandrov AV, Darkhabani Z, Edgell RC, English J, Frei D, Jamieson DG, Janardhan V, Janjua N, Janjua RM, Katzan I, Khatri P, Kirmani JF, Liebeskind DS, Linfante I, Nguyen TN, Saver JL, Shutter L, Xavier A, Yavagal D, Zaidat OO. PMID: 23008406; PMCID: PMC4109230.
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Endovascular recanalization in acute ischemic stroke: regionalized organization of care. Neurology. 2012 Sep 25; 79(13 Suppl 1):S3-4. Saver JL. PMID: 23008408.
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Design and rationale of the Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy (MR RESCUE) Trial. Int J Stroke. 2014 Jan; 9(1):110-6. Kidwell CS, Jahan R, Alger JR, Schaewe TJ, Guzy J, Starkman S, Elashoff R, Gornbein J, Nenov V, Saver JL, MR RESCUE Investigators. PMID: 22974139; PMCID: PMC3525782.
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Mechanical thrombectomy devices for treatment of stroke. Neurol Clin Pract. 2012 Sep; 2(3):231-235. Raychev R, Saver JL. PMID: 23634369; PMCID: PMC3613201.
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Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial. Lancet. 2012 Oct 06; 380(9849):1241-9. Saver JL, Jahan R, Levy EI, Jovin TG, Baxter B, Nogueira RG, Clark W, Budzik R, Zaidat OO, SWIFT Trialists. PMID: 22932715.
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Patterns, predictors, variations, and temporal trends in emergency medical service hospital prenotification for acute ischemic stroke. J Am Heart Assoc. 2012 Aug; 1(4):e002345. Lin CB, Peterson ED, Smith EE, Saver JL, Liang L, Xian Y, Olson DM, Shah BR, Hernandez AF, Schwamm LH, Fonarow GC. PMID: 23130167; PMCID: PMC3487363.
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Impact of Merci device fracture on clinical outcome of acute ischemic stroke after mechanical thrombectomy. CNS Neurosci Ther. 2012 Oct; 18(10):841-6. Shi ZS, Duckwiler GR, Loh Y, Liebeskind DS, Gonzalez NR, Tateshima S, Jahan R, Saver JL, Viñuela F. PMID: 22900956; PMCID: PMC4176619.
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Efficacy of folic acid supplementation in cardiovascular disease prevention: an updated meta-analysis of randomized controlled trials. Eur J Intern Med. 2012 Dec; 23(8):745-54. Yang HT, Lee M, Hong KS, Ovbiagele B, Saver JL. PMID: 22884409.
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Comparison of 30-day mortality models for profiling hospital performance in acute ischemic stroke with vs without adjustment for stroke severity. JAMA. 2012 Jul 18; 308(3):257-64. Fonarow GC, Pan W, Saver JL, Smith EE, Reeves MJ, Broderick JP, Kleindorfer DO, Sacco RL, Olson DM, Hernandez AF, Peterson ED, Schwamm LH. PMID: 22797643.
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Risk score for intracranial hemorrhage in patients with acute ischemic stroke treated with intravenous tissue-type plasminogen activator. Stroke. 2012 Sep; 43(9):2293-9. Menon BK, Saver JL, Prabhakaran S, Reeves M, Liang L, Olson DM, Peterson ED, Hernandez AF, Fonarow GC, Schwamm LH, Smith EE. PMID: 22811458.
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Emergency medical service hospital prenotification is associated with improved evaluation and treatment of acute ischemic stroke. Circ Cardiovasc Qual Outcomes. 2012 Jul 01; 5(4):514-22. Lin CB, Peterson ED, Smith EE, Saver JL, Liang L, Xian Y, Olson DM, Shah BR, Hernandez AF, Schwamm LH, Fonarow GC. PMID: 22787065.
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Telmisartan on top of antihypertensive treatment does not prevent progression of cerebral white matter lesions in the prevention regimen for effectively avoiding second strokes (PRoFESS) MRI substudy. Stroke. 2012 Sep; 43(9):2336-42. Weber R, Weimar C, Blatchford J, Hermansson K, Wanke I, Möller-Hartmann C, Gizewski ER, Forsting M, Demchuk AM, Sacco RL, Saver JL, Warach S, Diener HC, Diehl A, PRoFESS Imaging Substudy Group. PMID: 22738922.
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Effect of pre-diabetes on future risk of stroke: meta-analysis. BMJ. 2012 Jun 07; 344:e3564. Lee M, Saver JL, Hong KS, Song S, Chang KH, Ovbiagele B. PMID: 22677795; PMCID: PMC3370083.
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Growth of regional acute stroke systems of care in the United States in the first decade of the 21st century. Stroke. 2012 Jul; 43(7):1975-8. Song S, Saver J. PMID: 22669404; PMCID: PMC3413285.
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The hyperdense vessel sign on CT predicts successful recanalization with the Merci device in acute ischemic stroke. J Neurointerv Surg. 2013 Jul; 5(4):289-93. Froehler MT, Tateshima S, Duckwiler G, Jahan R, Gonzalez N, Vinuela F, Liebeskind D, Saver JL, Villablanca JP, UCLA Stroke Investigators. PMID: 22619467; PMCID: PMC4156587.
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Cerebral microbleeds after use of extracorporeal membrane oxygenation in children. J Neuroimaging. 2013 Jan; 23(1):75-8. Liebeskind DS, Sanossian N, Sapo ML, Saver JL. PMID: 22606942; PMCID: PMC4156585.
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Leukoaraiosis predicts parenchymal hematoma after mechanical thrombectomy in acute ischemic stroke. Stroke. 2012 Jul; 43(7):1806-11. Shi ZS, Loh Y, Liebeskind DS, Saver JL, Gonzalez NR, Tateshima S, Jahan R, Feng L, Vespa PM, Starkman S, Salamon N, Villablance JP, Ali LK, Ovbiagele B, Kim D, Viñuela F, Duckwiler GR. PMID: 22581819; PMCID: PMC3383878.
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Indirect revascularization for nonmoyamoya intracranial arterial stenoses: clinical and angiographic outcomes. J Neurosurg. 2012 Jul; 117(1):94-102. Dusick JR, Liebeskind DS, Saver JL, Martin NA, Gonzalez NR. PMID: 22559848; PMCID: PMC3929593.
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Relationship between neurologic deficit severity and final functional outcome shifts and strengthens during first hours after onset. Stroke. 2012 Jun; 43(6):1537-41. Saver JL, Altman H. PMID: 22492517; PMCID: PMC3509751.
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Anterior choroidal artery ischaemic patterns predict outcome of carotid occlusion. J Neurol Neurosurg Psychiatry. 2012 Jun; 83(6):586-90. Lee M, Saver JL, Hao Q, Starkman S, Salamon N, Ali LK, Kim D, Ovbiagele B, Song S, Raychev R, Abcede H, Fiaz R, Liebeskind DS, UCLA Stroke Investigators. PMID: 22492212; PMCID: PMC4157912.
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Statistical analysis of the primary outcome in acute stroke trials. Stroke. 2012 Apr; 43(4):1171-8. Bath PM, Lees KR, Schellinger PD, Altman H, Bland M, Hogg C, Howard G, Saver JL, European Stroke Organisation Outcomes Working Group. PMID: 22426314.
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Evidence from the scene: paramedic perspectives on involvement in out-of-hospital research. Ann Emerg Med. 2012 Nov; 60(5):641-50. Burges Watson DL, Sanoff R, Mackintosh JE, Saver JL, Ford GA, Price C, Starkman S, Eckstein M, Conwit R, Grace A, Murtagh MJ. PMID: 22387089; PMCID: PMC3690919.
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Relationship of national institutes of health stroke scale to 30-day mortality in medicare beneficiaries with acute ischemic stroke. J Am Heart Assoc. 2012 Feb; 1(1):42-50. Fonarow GC, Saver JL, Smith EE, Broderick JP, Kleindorfer DO, Sacco RL, Pan W, Olson DM, Hernandez AF, Peterson ED, Schwamm LH. PMID: 23130117; PMCID: PMC3487316.
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The value of arterial spin-labeled perfusion imaging in acute ischemic stroke: comparison with dynamic susceptibility contrast-enhanced MRI. Stroke. 2012 Apr; 43(4):1018-24. Wang DJ, Alger JR, Qiao JX, Hao Q, Hou S, Fiaz R, Gunther M, Pope WB, Saver JL, Salamon N, Liebeskind DS, UCLA Stroke Investigators. PMID: 22328551; PMCID: PMC3314714.
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Incomplete mechanical recanalization of middle cerebral artery occlusions facilitates endogenous recanalization within 5 h. J Neurointerv Surg. 2013 May; 5(3):217-20. Loh Y, Shi Z, Liebeskind D, Jahan R, Gonzalez N, Vespa PM, Starkman S, Saver JL, Tateshima S, Vinuela F, Duckwiler G. PMID: 22315286; PMCID: PMC4156597.
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Standardizing the structure of stroke clinical and epidemiologic research data: the National Institute of Neurological Disorders and Stroke (NINDS) Stroke Common Data Element (CDE) project. Stroke. 2012 Apr; 43(4):967-73. Saver JL, Warach S, Janis S, Odenkirchen J, Becker K, Benavente O, Broderick J, Dromerick AW, Duncan P, Elkind MS, Johnston K, Kidwell CS, Meschia JF, Schwamm L, National Institute of Neurological Disorders and Stroke (NINDS) Stroke Common Data Element Working G. PMID: 22308239; PMCID: PMC3493110.
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Thrombus branching and vessel curvature are important determinants of middle cerebral artery trunk recanalization with Merci thrombectomy devices. Stroke. 2012 Mar; 43(3):787-92. Zhu L, Liebeskind DS, Jahan R, Starkman S, Salamon N, Duckwiler G, Vinuela F, Tateshima S, Gonzalez N, Villablanca P, Ali LK, Kim D, Ovbiagele B, Froehler M, Tenser M, Saver JL. PMID: 22282888; PMCID: PMC3288443.
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Risk of recurrent stroke in patients with silent brain infarction in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) imaging substudy. Stroke. 2012 Feb; 43(2):350-5. Weber R, Weimar C, Wanke I, Möller-Hartmann C, Gizewski ER, Blatchford J, Hermansson K, Demchuk AM, Forsting M, Sacco RL, Saver JL, Warach S, Diener HC, Diehl A, PRoFESS Imaging Substudy Group. PMID: 22267825; PMCID: PMC3266606.
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Association of laterality and size of perfusion lesions on neurological deficit in acute supratentorial stroke. Int J Stroke. 2012 Jun; 7(4):293-7. Lee M, Saver JL, Alger JR, Hao Q, Salamon N, Starkman S, Ali LK, Ovbiagele B, Kim D, Villablanca JP, Froehler MT, Tenser MS, Liebeskind DS. PMID: 22151911; PMCID: PMC3310323.
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Renin-Angiotensin system modulators modestly reduce vascular risk in persons with prior stroke. Stroke. 2012 Jan; 43(1):113-9. Lee M, Saver JL, Hong KS, Hao Q, Chow J, Ovbiagele B. PMID: 22052520; PMCID: PMC4134883.
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Blood-brain barrier permeability derangements in posterior circulation ischemic stroke: frequency and relation to hemorrhagic transformation. J Neurol Sci. 2012 Feb 15; 313(1-2):142-6. Lee M, Saver JL, Alger JR, Hao Q, Starkman S, Ali LK, Kim D, Ovbiagele B, Vespa PM, Froehler MT, Tenser MS, Salamon N, Villablanca JP, Jahan R, Duckwiler GR, Tateshima S, Gonzalez N, Vinuela F, Liebeskind DS. PMID: 21945462; PMCID: PMC3254818.
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Effect of time to reperfusion on clinical outcome of anterior circulation strokes treated with thrombectomy: pooled analysis of the MERCI and Multi MERCI trials. Stroke. 2011 Nov; 42(11):3144-9. Nogueira RG, Smith WS, Sung G, Duckwiler G, Walker G, Roberts R, Saver JL, Liebeskind DS, MERCI and Multi MERCI Writing Committee. PMID: 21921278.
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Improving door-to-needle times in acute ischemic stroke: the design and rationale for the American Heart Association/American Stroke Association's Target: Stroke initiative. Stroke. 2011 Oct; 42(10):2983-9. Fonarow GC, Smith EE, Saver JL, Reeves MJ, Hernandez AF, Peterson ED, Sacco RL, Schwamm LH. PMID: 21885841.
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Stroke Treatment Academic Industry Roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies. Stroke. 2011 Sep; 42(9):2645-50. Albers GW, Goldstein LB, Hess DC, Wechsler LR, Furie KL, Gorelick PB, Hurn P, Liebeskind DS, Nogueira RG, Saver JL, STAIR VII Consortium. PMID: 21852620.
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Treatment of high risk symptomatic intracranial atherosclerosis with balloon mounted coronary stents and Wingspan stents: single center experience over a 10 year period. J Neurointerv Surg. 2012 Jan 01; 4(1):34-9. Tarlov N, Jahan R, Saver JL, Sayre JW, Ali LK, Kim D, Duckwiler GR, Tateshima S, Viñuela F, Liebeskind DS. PMID: 21990460.
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Does achieving an intensive versus usual blood pressure level prevent stroke? Ann Neurol. 2012 Jan; 71(1):133-40. Lee M, Saver JL, Hong KS, Hao Q, Ovbiagele B. PMID: 21796663.
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Stroke declines from third to fourth leading cause of death in the United States: historical perspective and challenges ahead. Stroke. 2011 Aug; 42(8):2351-5. Towfighi A, Saver JL. PMID: 21778445.
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Collateral flow averts hemorrhagic transformation after endovascular therapy for acute ischemic stroke. Stroke. 2011 Aug; 42(8):2235-9. Bang OY, Saver JL, Kim SJ, Kim GM, Chung CS, Ovbiagele B, Lee KH, Liebeskind DS, UCLA-Samsung Stroke Collaborators. PMID: 21737798.
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Improving reperfusion therapy for acute ischaemic stroke. J Thromb Haemost. 2011 Jul; 9 Suppl 1:333-43. Saver JL. PMID: 21781270.
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Optimal end points for acute stroke therapy trials: best ways to measure treatment effects of drugs and devices. Stroke. 2011 Aug; 42(8):2356-62. Saver JL. PMID: 21719772; PMCID: PMC3463240.
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Comparison of plasmin with recombinant tissue-type plasminogen activator in lysis of cerebral thromboemboli retrieved from patients with acute ischemic stroke. Stroke. 2011 Aug; 42(8):2222-8. Marder VJ, Blinc A, Gruber T, Tratar G, Sabovic M, Starkman S, Jahan R, Duckwiler G, Vinuela F, Tateshima S, Liebeskind D, Ovbiagele B, Ali L, Kim D, Gonzalez N, Vespa PM, Saver JL. PMID: 21700944; PMCID: PMC3217902.
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Partial aortic occlusion for cerebral perfusion augmentation: safety and efficacy of NeuroFlo in Acute Ischemic Stroke trial. Stroke. 2011 Jun; 42(6):1680-90. Shuaib A, Bornstein NM, Diener HC, Dillon W, Fisher M, Hammer MD, Molina CA, Rutledge JN, Saver JL, Schellinger PD, Shownkeen H, SENTIS Trial Investigators. PMID: 21566232.
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Declining stroke and vascular event recurrence rates in secondary prevention trials over the past 50 years and consequences for current trial design. Circulation. 2011 May 17; 123(19):2111-9. Hong KS, Yegiaian S, Lee M, Lee J, Saver JL. PMID: 21536995; PMCID: PMC3118516.
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Weighting components of composite end points in clinical trials: an approach using disability-adjusted life-years. Stroke. 2011 Jun; 42(6):1722-9. Hong KS, Ali LK, Selco SL, Fonarow GC, Saver JL. PMID: 21527766; PMCID: PMC3109505.
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Efficacy of fibrates for cardiovascular risk reduction in persons with atherogenic dyslipidemia: a meta-analysis. Atherosclerosis. 2011 Aug; 217(2):492-8. Lee M, Saver JL, Towfighi A, Chow J, Ovbiagele B. PMID: 21592479.
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Collaterals dramatically alter stroke risk in intracranial atherosclerosis. Ann Neurol. 2011 Jun; 69(6):963-74. Liebeskind DS, Cotsonis GA, Saver JL, Lynn MJ, Turan TN, Cloft HJ, Chimowitz MI, Warfarin-Aspirin Symptomatic Intracranial Disease (WASID) Investigators. PMID: 21437932; PMCID: PMC3117968.
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CT and MRI early vessel signs reflect clot composition in acute stroke. Stroke. 2011 May; 42(5):1237-43. Liebeskind DS, Sanossian N, Yong WH, Starkman S, Tsang MP, Moya AL, Zheng DD, Abolian AM, Kim D, Ali LK, Shah SH, Towfighi A, Ovbiagele B, Kidwell CS, Tateshima S, Jahan R, Duckwiler GR, Viñuela F, Salamon N, Villablanca JP, Vinters HV, Marder VJ, Saver JL. PMID: 21393591; PMCID: PMC3094751.
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Randomized, controlled trial of an intervention to enable stroke survivors throughout the Los Angeles County safety net to "stay with the guidelines". Circ Cardiovasc Qual Outcomes. 2011 Mar; 4(2):229-34. Cheng EM, Cunningham WE, Towfighi A, Sanossian N, Bryg RJ, Anderson TL, Guterman JJ, Gross-Schulman SG, Beanes S, Jones AS, Liu H, Ettner SL, Saver JL, Vickrey BG. PMID: 21406671; PMCID: PMC3065242.
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Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes associated with door-to-needle times within 60 minutes. Circulation. 2011 Feb 22; 123(7):750-8. Fonarow GC, Smith EE, Saver JL, Reeves MJ, Bhatt DL, Grau-Sepulveda MV, Olson DM, Hernandez AF, Peterson ED, Schwamm LH. PMID: 21311083.
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Stroke Council and American Stroke Association update. Stroke. 2011 Mar; 42(3):830-1. Saver JL, Wasiak H. PMID: 21273568.
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Collateral flow predicts response to endovascular therapy for acute ischemic stroke. Stroke. 2011 Mar; 42(3):693-9. Bang OY, Saver JL, Kim SJ, Kim GM, Chung CS, Ovbiagele B, Lee KH, Liebeskind DS. PMID: 21233472; PMCID: PMC3051344.
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Influence of height on the clinical characteristics and prognosis of patients with ischemic stroke. Neurologist. 2011 Jan; 17(1):21-3. Ali LK, Saver JL, Liebeskind DS, Pineda S, Ovbiagele B. PMID: 21192187.
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Collateral circulation in symptomatic intracranial atherosclerosis. J Cereb Blood Flow Metab. 2011 May; 31(5):1293-301. Liebeskind DS, Cotsonis GA, Saver JL, Lynn MJ, Cloft HJ, Chimowitz MI, Warfarin–Aspirin Symptomatic Intracranial Disease (WASID) Investigators. PMID: 21157476; PMCID: PMC3099635.
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Preprocedural basal ganglionic infarction increases the risk of hemorrhagic transformation but not worse outcome following successful recanalization of acute middle cerebral artery occlusions. World Neurosurg. 2010 Dec; 74(6):636-40. Loh Y, Liebeskind DS, Towfighi A, Vespa P, Starkman S, Saver JL, Gonzalez NR, Tateshima S, Jahan R, Shi ZS, Viñuela F, Duckwiler GR. PMID: 21492632.
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Predictors of subarachnoid hemorrhage in acute ischemic stroke with endovascular therapy. Stroke. 2010 Dec; 41(12):2775-81. Shi ZS, Liebeskind DS, Loh Y, Saver JL, Starkman S, Vespa PM, Gonzalez NR, Tateshima S, Jahan R, Feng L, Miller C, Ali LK, Ovbiagele B, Kim D, Duckwiler GR, Viñuela F, UCLA Endovascular Stroke Therapy Investigators. PMID: 21051673; PMCID: PMC3388807.
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Leukoaraiosis and collaterals in acute ischemic stroke. J Neuroimaging. 2011 Jul; 21(3):232-5. Sanossian N, Ovbiagele B, Saver JL, Alger JR, Starkman S, Kim D, Ohanian AG, Buck BH, Ali LK, Duckwiler GR, Jahan R, Viñuela F, Liebeskind DS. PMID: 20977524; PMCID: PMC3030936.
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Safety of intravenous fibrinolysis in imaging-confirmed single penetrator artery infarcts. Stroke. 2010 Nov; 41(11):2587-91. Lee SJ, Saver JL, Liebeskind DS, Ali L, Ovbiagele B, Kim D, Vespa P, Froehler M, Tenser M, Gadhia J, Starkman S. PMID: 20947857; PMCID: PMC3034158.
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Addition of brain and carotid imaging to the ABCD² score to identify patients at early risk of stroke after transient ischaemic attack: a multicentre observational study. Lancet Neurol. 2010 Nov; 9(11):1060-9. Merwick A, Albers GW, Amarenco P, Arsava EM, Ay H, Calvet D, Coutts SB, Cucchiara BL, Demchuk AM, Furie KL, Giles MF, Labreuche J, Lavallée PC, Mas JL, Olivot JM, Purroy F, Rothwell PM, Saver JL, Sheehan OC, Stack JP, Walsh C, Kelly PJ. PMID: 20934388.
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Impact of microalbuminuria on incident stroke: a meta-analysis. Stroke. 2010 Nov; 41(11):2625-31. Lee M, Saver JL, Chang KH, Liao HW, Chang SC, Ovbiagele B. PMID: 20930164.
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Impact of elevated cystatin C level on cardiovascular disease risk in predominantly high cardiovascular risk populations: a meta-analysis. Circ Cardiovasc Qual Outcomes. 2010 Nov; 3(6):675-83. Lee M, Saver JL, Huang WH, Chow J, Chang KH, Ovbiagele B. PMID: 20923994.
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Low glomerular filtration rate and risk of stroke: meta-analysis. BMJ. 2010 Sep 30; 341:c4249. Lee M, Saver JL, Chang KH, Liao HW, Chang SC, Ovbiagele B. PMID: 20884696; PMCID: PMC2948650.
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Risk score for in-hospital ischemic stroke mortality derived and validated within the Get With the Guidelines-Stroke Program. Circulation. 2010 Oct 12; 122(15):1496-504. Smith EE, Shobha N, Dai D, Olson DM, Reeves MJ, Saver JL, Hernandez AF, Peterson ED, Fonarow GC, Schwamm LH. PMID: 20876438.
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Graphic reanalysis of the two NINDS-tPA trials confirms substantial treatment benefit. Stroke. 2010 Oct; 41(10):2381-90. Saver JL, Gornbein J, Starkman S. PMID: 20829518; PMCID: PMC2949055.
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Strokes with minor symptoms: an exploratory analysis of the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator trials. Stroke. 2010 Nov; 41(11):2581-6. Khatri P, Kleindorfer DO, Yeatts SD, Saver JL, Levine SR, Lyden PD, Moomaw CJ, Palesch YY, Jauch EC, Broderick JP. PMID: 20814000; PMCID: PMC2964419.
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Stunned brain syndrome: serial diffusion perfusion MRI of delayed recovery following revascularisation for acute ischaemic stroke. J Neurol Neurosurg Psychiatry. 2011 Jan; 82(1):27-32. Bang OY, Liebeskind DS, Saver JL, Kim GM, Chung CS, Lee KH, UCLA-Samsung Stroke Collaborators. PMID: 20802028.
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Disability status at 1 month is a reliable proxy for final ischemic stroke outcome. Neurology. 2010 Aug 24; 75(8):688-92. Ovbiagele B, Lyden PD, Saver JL, VISTA Collaborators. PMID: 20733143; PMCID: PMC2931650.
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Level of albuminuria and risk of stroke: systematic review and meta-analysis. Cerebrovasc Dis. 2010; 30(5):464-9. Lee M, Saver JL, Chang KH, Ovbiagele B. PMID: 20733300; PMCID: PMC2992641.
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Patterns and predictors of discharge statin prescription among hospitalized patients with intracerebral hemorrhage. Stroke. 2010 Oct; 41(10):2271-7. Ovbiagele B, Schwamm LH, Smith EE, Hernandez AF, Olson DM, Pan W, Fonarow GC, Saver JL. PMID: 20724709.
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Stroke: working toward a prioritized world agenda. Int J Stroke. 2010 Aug; 5(4):238-56. Hachinski V, Donnan GA, Gorelick PB, Hacke W, Cramer SC, Kaste M, Fisher M, Brainin M, Buchan AM, Lo EH, Skolnick BE, Furie KL, Hankey GJ, Kivipelto M, Morris J, Rothwell PM, Sacco RL, Smith SC, Wang Y, Bryer A, Ford GA, Iadecola C, Martins SC, Saver J, Skvortsova V, Bayley M, Bednar MM, Duncan P, Enney L, Finklestein S, Jones TA, Kalra L, Kleim J, Nitkin R, Teasell R, Weiller C, Desai B, Goldberg MP, Heiss WD, Saarelma O, Schwamm LH, Shinohara Y, Trivedi B, Wahlgren N, Wong LK, Hakim A, Norrving B, Prudhomme S, Bornstein NM, Davis SM, Goldstein LB, Leys D, Tuomilehto J. PMID: 20636706; PMCID: PMC3712839.
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Intercontinental elicitation of informed consent for enrollment in stroke research. Cerebrovasc Dis. 2010 Aug; 30(3):323-4. Sanossian N, Starkman S, Eckstein M, Stratton S, Pratt F, Conwit R, Saver JL, FAST-MAG Trial Investigators. PMID: 20664268; PMCID: PMC2939993.
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Prognostic value of Framingham Cardiovascular Risk Score in hospitalized stroke patients. J Stroke Cerebrovasc Dis. 2011 May-Jun; 20(3):222-6. Ovbiagele B, Liebeskind DS, Kim D, Ali LK, Pineda S, Saver JL. PMID: 20656518.
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Targeting the brain: neuroprotection and neurorestoration in ischemic stroke. Pharmacotherapy. 2010 Jul; 30(7 Pt 2):62S-9S. Saver JL. PMID: 20575624.
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Years of optimum health lost due to complications after acute ischemic stroke: disability-adjusted life-years analysis. Stroke. 2010 Aug; 41(8):1758-65. Hong KS, Saver JL, Kang DW, Bae HJ, Yu KH, Koo J, Han MK, Cho YJ, Park JM, Lee BC. PMID: 20595674; PMCID: PMC2937160.
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The "golden hour" and acute brain ischemia: presenting features and lytic therapy in >30,000 patients arriving within 60 minutes of stroke onset. Stroke. 2010 Jul; 41(7):1431-9. Saver JL, Smith EE, Fonarow GC, Reeves MJ, Zhao X, Olson DM, Schwamm LH, GWTG-Stroke Steering Committee and Investigators. PMID: 20522809; PMCID: PMC2909671.
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Stroke: working toward a prioritized world agenda. Stroke. 2010 Jun; 41(6):1084-99. Hachinski V, Donnan GA, Gorelick PB, Hacke W, Cramer SC, Kaste M, Fisher M, Brainin M, Buchan AM, Lo EH, Skolnick BE, Furie KL, Hankey GJ, Kivipelto M, Morris J, Rothwell PM, Sacco RL, Smith SC, Wang Y, Bryer A, Ford GA, Iadecola C, Martins SC, Saver J, Skvortsova V, Bayley M, Bednar MM, Duncan P, Enney L, Finklestein S, Jones TA, Kalra L, Kleim J, Nitkin R, Teasell R, Weiller C, Desai B, Goldberg MP, Heiss WD, Saarelma O, Schwamm LH, Shinohara Y, Trivedi B, Wahlgren N, Wong LK, Hakim A, Norrving B, Prudhomme S, Bornstein NM, Davis SM, Goldstein LB, Leys D, Tuomilehto J. PMID: 20498453; PMCID: PMC3712843.
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Recent nationwide trends in discharge statin treatment of hospitalized patients with stroke. Stroke. 2010 Jul; 41(7):1508-13. Ovbiagele B, Schwamm LH, Smith EE, Hernandez AF, Olson DM, Pan W, Fonarow GC, Saver JL. PMID: 20508182.
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Stroke: working toward a prioritized world agenda. Cerebrovasc Dis. 2010; 30(2):127-47. Hachinski V, Donnan GA, Gorelick PB, Hacke W, Cramer SC, Kaste M, Fisher M, Brainin M, Buchan AM, Lo EH, Skolnick BE, Furie KL, Hankey GJ, Kivipelto M, Morris J, Rothwell PM, Sacco RL, Smith SC, Wang Y, Bryer A, Ford GA, Iadecola C, Martins SC, Saver J, Skvortsova V, Bayley M, Bednar MM, Duncan P, Enney L, Finklestein S, Jones TA, Kalra L, Kleim J, Nitkin R, Teasell R, Weiller C, Desai B, Goldberg MP, Heiss WD, Saarelma O, Schwamm LH, Shinohara Y, Trivedi B, Wahlgren N, Wong LK, Hakim A, Norrving B, Prudhomme S, Bornstein NM, Davis SM, Goldstein LB, Leys D, Tuomilehto J, Stroke Synergium. PMID: 20516682; PMCID: PMC3221270.
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Alteplase for ischaemic stroke--much sooner is much better. Lancet. 2010 May 15; 375(9727):1667-8. Saver JL, Levine SR. PMID: 20472152.
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Renal dysfunction and discharge destination in patients with intracerebral hemorrhage. J Stroke Cerebrovasc Dis. 2011 Mar-Apr; 20(2):145-9. Ovbiagele B, Pineda S, Saver JL. PMID: 20472461.
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Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: a meta-analysis. Stroke. 2010 Jun; 41(6):1205-12. Lee M, Hong KS, Chang SC, Saver JL. PMID: 20413740; PMCID: PMC2909661.
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Efficacy of intra-arterial fibrinolysis for acute ischemic stroke: meta-analysis of randomized controlled trials. Stroke. 2010 May; 41(5):932-7. Lee M, Hong KS, Saver JL. PMID: 20360549.
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Improving the reliability of stroke disability grading in clinical trials and clinical practice: the Rankin Focused Assessment (RFA). Stroke. 2010 May; 41(5):992-5. Saver JL, Filip B, Hamilton S, Yanes A, Craig S, Cho M, Conwit R, Starkman S, FAST-MAG Investigators and Coordinators. PMID: 20360551; PMCID: PMC2930146.
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Swift or sure?: The acceptable rate of neurovascular mimics among IV tPA-treated patients. Neurology. 2010 Apr 27; 74(17):1336-7. Saver JL, Barsan WG. PMID: 20335563.
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Joint modeling of longitudinal ordinal data and competing risks survival times and analysis of the NINDS rt-PA stroke trial. Stat Med. 2010 Feb 28; 29(5):546-57. Li N, Elashoff RM, Li G, Saver J. PMID: 19943331; PMCID: PMC2822130.
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Translating evidence into practice: a decade of efforts by the American Heart Association/American Stroke Association to reduce death and disability due to stroke: a presidential advisory from the American Heart Association/American Stroke Association. Stroke. 2010 May; 41(5):1051-65. Schwamm L, Fayad P, Acker JE, Duncan P, Fonarow GC, Girgus M, Goldstein LB, Gregory T, Kelly-Hayes M, Sacco RL, Saver JL, Segrest W, Solis P, Yancy CW. PMID: 20181677.
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Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-stroke. Circ Cardiovasc Qual Outcomes. 2010 May; 3(3):291-302. Fonarow GC, Reeves MJ, Smith EE, Saver JL, Zhao X, Olson DW, Hernandez AF, Peterson ED, Schwamm LH, GWTG-Stroke Steering Committee and Investigators. PMID: 20177051.
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Age-related differences in characteristics, performance measures, treatment trends, and outcomes in patients with ischemic stroke. Circulation. 2010 Feb 23; 121(7):879-91. Fonarow GC, Reeves MJ, Zhao X, Olson DM, Smith EE, Saver JL, Schwamm LH, Get With the Guidelines-Stroke Steering Committee and Investigators. PMID: 20142445.
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Years of disability-adjusted life gained as a result of thrombolytic therapy for acute ischemic stroke. Stroke. 2010 Mar; 41(3):471-7. Hong KS, Saver JL. PMID: 20133917.
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Response to: "A graphic reanalysis of the NINDS Trial". Ann Emerg Med. 2010 Feb; 55(2):226-7; author reply 229. Saver JL, Gornbein J, Starkman S. PMID: 20116034; PMCID: PMC2839893.
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Differential pathophysiological mechanisms of stroke evolution between new lesions and lesion growth: perfusion-weighted imaging study. Cerebrovasc Dis. 2010; 29(4):328-35. Bang OY, Kim GM, Chung CS, Kim SJ, Kim KH, Jeon P, Saver JL, Liebeskind DS, Lee KH. PMID: 20130398.
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Impact of baseline tissue status (diffusion-weighted imaging lesion) versus perfusion status (severity of hypoperfusion) on hemorrhagic transformation. Stroke. 2010 Mar; 41(3):e135-42. Kim JH, Bang OY, Liebeskind DS, Ovbiagele B, Kim GM, Chung CS, Lee KH, Saver JL, UCLA-Samsung Stroke Collaborators. PMID: 20075362.
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Therapeutic milestone: stroke declines from the second to the third leading organ- and disease-specific cause of death in the United States. Stroke. 2010 Mar; 41(3):499-503. Towfighi A, Ovbiagele B, Saver JL. PMID: 20075347.
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Assessment and improvement of figures to visually convey benefit and risk of stroke thrombolysis. Stroke. 2010 Feb; 41(2):300-6. Gadhia J, Starkman S, Ovbiagele B, Ali L, Liebeskind D, Saver JL. PMID: 20056928; PMCID: PMC2909659.
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Strong independent correlation of proteinuria with cerebral microbleeds in patients with stroke and transient ischemic attack. Arch Neurol. 2010 Jan; 67(1):45-50. Ovbiagele B, Liebeskind DS, Pineda S, Saver JL. PMID: 20065128.
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Target brain: neuroprotection and neurorestoration in ischemic stroke. Rev Neurol Dis. 2010; 7 Suppl 1:S14-21. Saver JL. PMID: 20410866.
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Boosting the chances to improve stroke treatment. Stroke. 2010 Mar; 41(3):e143-50. Cobo E, Secades JJ, Miras F, González JA, Saver JL, Corchero C, Rius R, Dàvalos A. PMID: 20035072.
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Need to clarify Thrombolysis In Myocardial Ischemia (TIMI) scale scoring method in the Penumbra Pivotal Stroke Trial. Stroke. 2010 Feb; 41(2):e115-6. Saver JL, Liebeskind DS, Nogueira RG, Jahan R. PMID: 20035075.
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Characteristics of patients with target magnetic resonance mismatch profile: data from two geographically and racially distinct populations. Cerebrovasc Dis. 2010; 29(1):87-94. Bang OY, Saver JL, Lee KH, Kim GM, Chung CS, Kim SJ, Ovbiagele B, Alger JR, Liebeskind DS, UCLA-Samsung Stroke Collaborators. PMID: 19907169.
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Day-90 acute ischemic stroke outcomes can be derived from early functional activity level. Cerebrovasc Dis. 2010; 29(1):50-6. Ovbiagele B, Saver JL. PMID: 19893312.
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Vision and creation of the American Heart Association pharmaceutical roundtable outcomes research centers. Circ Cardiovasc Qual Outcomes. 2009 Nov; 2(6):663-70. Peterson ED, Spertus JA, Cohen DJ, Hlatky MA, Go AS, Vickrey BG, Saver JL, Hinton PC. PMID: 20031906; PMCID: PMC4567255.
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Simultaneous ring voice-over-Internet phone system enables rapid physician elicitation of explicit informed consent in prehospital stroke treatment trials. Cerebrovasc Dis. 2009; 28(6):539-44. Sanossian N, Starkman S, Liebeskind DS, Ali LK, Restrepo L, Hamilton S, Conwit R, Saver JL, FAST-MAG Trial Investigators. PMID: 19844092; PMCID: PMC2914352.
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Indices of kidney dysfunction and discharge outcomes in hospitalized stroke patients without known renal disease. Cerebrovasc Dis. 2009; 28(6):582-8. Ovbiagele B, Sanossian N, Liebeskind DS, Kim D, Ali LK, Pineda S, Saver JL. PMID: 19844098.
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Quantifying the value of stroke disability outcomes: WHO global burden of disease project disability weights for each level of the modified Rankin Scale. Stroke. 2009 Dec; 40(12):3828-33. Hong KS, Saver JL. PMID: 19797698; PMCID: PMC2788070.
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Impact of hyperlipidemia and statins on ischemic stroke outcomes after intra-arterial fibrinolysis and percutaneous mechanical embolectomy. Cerebrovasc Dis. 2009; 28(4):384-90. Restrepo L, Bang OY, Ovbiagele B, Ali L, Kim D, Liebeskind DS, Starkman S, Vinuela F, Duckwiler GR, Jahan R, Saver JL. PMID: 19713698; PMCID: PMC2909704.
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Optimizing screening and management of asymptomatic coronary artery disease in patients with stroke and patients with transient ischemic attack. Stroke. 2009 Oct; 40(10):3407-9. Ovbiagele B, Liebeskind DS, Kim D, Ali LK, Pineda S, Saver JL. PMID: 19679844.
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Basal ganglionic infarction before mechanical thrombectomy predicts poor outcome. Stroke. 2009 Oct; 40(10):3315-20. Loh Y, Towfighi A, Liebeskind DS, MacArthur DL, Vespa P, Gonzalez NR, Tateshima S, Starkman S, Saver JL, Shi ZS, Jahan R, Viñuela F, Duckwiler GR. PMID: 19661477.
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Number needed to treat to benefit and to harm for intravenous tissue plasminogen activator therapy in the 3- to 4.5-hour window: joint outcome table analysis of the ECASS 3 trial. Stroke. 2009 Jul; 40(7):2433-7. Saver JL, Gornbein J, Grotta J, Liebeskind D, Lutsep H, Schwamm L, Scott P, Starkman S. PMID: 19498197; PMCID: PMC2724988.
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Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials. Stroke. 2009 Jul; 40(7):2594-600. Saver JL, Albers GW, Dunn B, Johnston KC, Fisher M, STAIR VI Consortium. PMID: 19478212; PMCID: PMC2761073.
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Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke. 2009 Aug; 40(8):2945-8. Del Zoppo GJ, Saver JL, Jauch EC, Adams HP, American Heart Association Stroke Council. PMID: 19478221; PMCID: PMC2782817.
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Comprehensive overview of nursing and interdisciplinary care of the acute ischemic stroke patient: a scientific statement from the American Heart Association. Stroke. 2009 Aug; 40(8):2911-44. Summers D, Leonard A, Wentworth D, Saver JL, Simpson J, Spilker JA, Hock N, Miller E, Mitchell PH, American Heart Association Council on Cardiovascular Nursing and the Stroke Council. PMID: 19478222.
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Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke. 2009 Jun; 40(6):2276-93. Easton JD, Saver JL, Albers GW, Alberts MJ, Chaturvedi S, Feldmann E, Hatsukami TS, Higashida RT, Johnston SC, Kidwell CS, Lutsep HL, Miller E, Sacco RL, American Heart Association, American Stroke Association Stroke Council, Council on Cardiovascular Surgery and Anesthesia, Council on Cardiovascular Radiology and Intervention, Council on Cardiovascular Nursing, Interdisciplinary Council on Peripheral Vascular Disease. PMID: 19423857.
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Clinical determinants of infarct pattern subtypes in large vessel atherosclerotic stroke. J Neurol. 2009 Apr; 256(4):591-9. Bang OY, Ovbiagele B, Liebeskind DS, Restrepo L, Yoon SR, Saver JL. PMID: 19444533; PMCID: PMC2745818.
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Impact of metabolic syndrome on distribution of cervicocephalic atherosclerosis: data from a diverse race-ethnic group. J Neurol Sci. 2009 Sep 15; 284(1-2):40-5. Bang OY, Saver JL, Liebeskind DS, Pineda S, Yun SW, Ovbiagele B. PMID: 19398114; PMCID: PMC2721913.
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Dispatcher recognition of stroke using the National Academy Medical Priority Dispatch System. Stroke. 2009 Jun; 40(6):2027-30. Buck BH, Starkman S, Eckstein M, Kidwell CS, Haines J, Huang R, Colby D, Saver JL. PMID: 19390065; PMCID: PMC2711028.
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Treatment time-specific number needed to treat estimates for tissue plasminogen activator therapy in acute stroke based on shifts over the entire range of the modified Rankin Scale. Stroke. 2009 Jun; 40(6):2079-84. Lansberg MG, Schrooten M, Bluhmki E, Thijs VN, Saver JL. PMID: 19372447; PMCID: PMC2881642.
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Identifying patients at high risk for poor outcome after intra-arterial therapy for acute ischemic stroke. Stroke. 2009 May; 40(5):1780-5. Hallevi H, Barreto AD, Liebeskind DS, Morales MM, Martin-Schild SB, Abraham AT, Gadia J, Saver JL, UCLA Intra-Arterial Therapy Investigators, Grotta JC, Savitz SI. PMID: 19359652; PMCID: PMC4138312.
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Results of the MRI substudy of the intravenous magnesium efficacy in stroke trial. Stroke. 2009 May; 40(5):1704-9. Kidwell CS, Lees KR, Muir KW, Chen C, Davis SM, De Silva DA, Weir CJ, Starkman S, Alger JR, Saver JL, MR IMAGES Investigators. PMID: 19299636; PMCID: PMC2694570.
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Contrast agent dose effects in cerebral dynamic susceptibility contrast magnetic resonance perfusion imaging. J Magn Reson Imaging. 2009 Jan; 29(1):52-64. Alger JR, Schaewe TJ, Lai TC, Frew AJ, Vespa PM, Etchepare M, Liebeskind DS, Saver JL, Kidwell SC. PMID: 19097106; PMCID: PMC2731672.
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A care pathway to boost influenza vaccination rates among inpatients with acute ischemic stroke and transient ischemic attack. J Stroke Cerebrovasc Dis. 2009 Jan; 18(1):38-40. Ovbiagele B, McNair N, Pineda S, Liebeskind DS, Ali LK, Saver JL. PMID: 19110143; PMCID: PMC2717626.
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Treatment effects for which shift or binary analyses are advantageous in acute stroke trials. Neurology. 2009 Apr 14; 72(15):1310-5. Saver JL, Gornbein J. PMID: 19092107; PMCID: PMC2677490.
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Patterns and predictors of blood-brain barrier permeability derangements in acute ischemic stroke. Stroke. 2009 Feb; 40(2):454-61. Bang OY, Saver JL, Alger JR, Shah SH, Buck BH, Starkman S, Ovbiagele B, Liebeskind DS, UCLA MRI Permeability Investigators. PMID: 19038915.
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Comparison of mechanical embolectomy and intraarterial thrombolysis in acute ischemic stroke within the MCA: MERCI and Multi MERCI compared to PROACT II. Neurocrit Care. 2009; 10(1):43-9. Josephson SA, Saver JL, Smith WS, Merci and Multi Merci Investigators. PMID: 19030784.
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Age-distinct predictors of symptomatic cervicocephalic atherosclerosis. Cerebrovasc Dis. 2009; 27(1):13-21. Bang OY, Saver JL, Liebeskind DS, Lee PH, Sheen SS, Yoon SR, Yun SW, Kim GM, Chung CS, Lee KH, Ovbiagele B. PMID: 19018133; PMCID: PMC2702490.
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Cryptogenic stroke and patent foramen ovale. Curr Opin Cardiol. 2008 Nov; 23(6):537-44. Thaler DE, Saver JL. PMID: 18830067.
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Clinical usefulness of a biomarker-based diagnostic test for acute stroke: the Biomarker Rapid Assessment in Ischemic Injury (BRAIN) study. Stroke. 2009 Jan; 40(1):77-85. Laskowitz DT, Kasner SE, Saver J, Remmel KS, Jauch EC, BRAIN Study Group. PMID: 18948614.
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Impact of reperfusion after 3 hours of symptom onset on tissue fate in acute cerebral ischemia. J Neuroimaging. 2009 Oct; 19(4):317-22. Bang OY, Liebeskind DS, Buck BH, Yoon SR, Alger JR, Ovbiagele B, Saver JL, UCLA MRI Investigators. PMID: 19021836; PMCID: PMC2755618.
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Proposal for a universal definition of cerebral infarction. Stroke. 2008 Nov; 39(11):3110-5. Saver JL. PMID: 18703806.
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Factors associated with the steep increase in late-midlife stroke occurrence among US men. J Stroke Cerebrovasc Dis. 2008 Jul-Aug; 17(4):165-8. Towfighi A, Saver JL, Engelhardt R, Ovbiagele B. PMID: 18589334; PMCID: PMC2728439.
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Serum calcium as prognosticator in ischemic stroke. Stroke. 2008 Aug; 39(8):2231-6. Ovbiagele B, Starkman S, Teal P, Lyden P, Kaste M, Davis SM, Hacke W, Fierus M, Saver JL, VISTA Investigators. PMID: 18583560.
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Outcome analysis in clinical trial design for acute stroke: physicians' attitudes and choices. Cerebrovasc Dis. 2008; 26(2):156-62. Savitz SI, Benatar M, Saver JL, Fisher M. PMID: 18560219.
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A brief prehospital stroke severity scale identifies ischemic stroke patients harboring persisting large arterial occlusions. Stroke. 2008 Aug; 39(8):2264-7. Nazliel B, Starkman S, Liebeskind DS, Ovbiagele B, Kim D, Sanossian N, Ali L, Buck B, Villablanca P, Vinuela F, Duckwiler G, Jahan R, Saver JL. PMID: 18556587; PMCID: PMC2743906.
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Development and validation of a simple conversion model for comparison of intracerebral hemorrhage volumes measured on CT and gradient recalled echo MRI. Stroke. 2008 Jul; 39(7):2017-20. Burgess RE, Warach S, Schaewe TJ, Copenhaver BR, Alger JR, Vespa P, Martin N, Saver JL, Kidwell CS. PMID: 18483414; PMCID: PMC2756493.
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Association of serum bilirubin with ischemic stroke outcomes. J Stroke Cerebrovasc Dis. 2008 May-Jun; 17(3):147-52. Pineda S, Bang OY, Saver JL, Starkman S, Yun SW, Liebeskind DS, Kim D, Ali LK, Shah SH, Ovbiagele B. PMID: 18436156; PMCID: PMC2731670.
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Image-guided endoscopic evacuation of spontaneous intracerebral hemorrhage. Surg Neurol. 2008 May; 69(5):441-6; discussion 446. Miller CM, Vespa P, Saver JL, Kidwell CS, Carmichael ST, Alger J, Frazee J, Starkman S, Liebeskind D, Nenov V, Elashoff R, Martin N. PMID: 18424298; PMCID: PMC4160887.
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Outpatient practice patterns after stroke hospitalization among neurologists. Stroke. 2008 Jun; 39(6):1850-4. Ovbiagele B, Drogan O, Koroshetz WJ, Fayad P, Saver JL. PMID: 18388342.
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Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke. 2008 Apr; 39(4):1205-12. Smith WS, Sung G, Saver J, Budzik R, Duckwiler G, Liebeskind DS, Lutsep HL, Rymer MM, Higashida RT, Starkman S, Gobin YP, Multi MERCI Investigators, Frei D, Grobelny T, Hellinger F, Huddle D, Kidwell C, Koroshetz W, Marks M, Nesbit G, Silverman IE. PMID: 18309168.
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Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke. Cerebrovasc Dis. 2008; 25(4):338-43. Kidwell CS, Latour L, Saver JL, Alger JR, Starkman S, Duckwiler G, Jahan R, Vinuela F, UCLA Thrombolysis Investigators, Kang DW, Warach S. PMID: 18303253.
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Diagnosis of lacunar infarcts within 6 hours of onset by clinical and CT criteria versus MRI. J Neuroimaging. 2008 Jan; 18(1):66-72. Rajajee V, Kidwell C, Starkman S, Ovbiagele B, Alger J, Villablanca P, Saver JL, UCLA MRI Acute Stroke Investigators. PMID: 18190499.
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In-hospital initiation of secondary prevention is associated with improved vascular outcomes at 3 months. J Stroke Cerebrovasc Dis. 2008 Jan-Feb; 17(1):5-8. Rahiman A, Saver JL, Porter V, Buxton W, McNair N, Razinia T, Ovbiagele B. PMID: 18190814.
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Citicoline: update on a promising and widely available agent for neuroprotection and neurorepair. Rev Neurol Dis. 2008; 5(4):167-77. Saver JL. PMID: 19122569.
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Early neutrophilia is associated with volume of ischemic tissue in acute stroke. Stroke. 2008 Feb; 39(2):355-60. Buck BH, Liebeskind DS, Saver JL, Bang OY, Yun SW, Starkman S, Ali LK, Kim D, Villablanca JP, Salamon N, Razinia T, Ovbiagele B. PMID: 18162626.
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Data that may shed some light on: "arguments against insisting on randomized trials for PFO closure". Catheter Cardiovasc Interv. 2007 Nov 15; 70(6):904-5; author reply 906. Carroll J, Onorato E, Saver J, Smalling R, Thaler D, Tobis J. PMID: 18022894.
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Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials. Stroke. 2007 Nov; 38(11):3055-62. Saver JL. PMID: 17916765.
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Clinical trial registries. JAMA. 2007 Oct 03; 298(13):1514; author reply 1515. Saver JL. PMID: 17911494.
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Cryptogenic stroke in patients with patent foramen ovale. Curr Atheroscler Rep. 2007 Oct; 9(4):319-25. Saver JL. PMID: 18173960.
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Implementation strategies for emergency medical services within stroke systems of care: a policy statement from the American Heart Association/American Stroke Association Expert Panel on Emergency Medical Services Systems and the Stroke Council. Stroke. 2007 Nov; 38(11):3097-115. Acker JE, Pancioli AM, Crocco TJ, Eckstein MK, Jauch EC, Larrabee H, Meltzer NM, Mergendahl WC, Munn JW, Prentiss SM, Sand C, Saver JL, Eigel B, Gilpin BR, Schoeberl M, Solis P, Bailey JR, Horton KB, Stranne SK, American Heart Association, American Stroke Association Expert Panel on Emergency Medical Services Systems, Stroke Council. PMID: 17901393.
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Prior antiplatelet use and infarct volume in ischemic stroke. J Neurol Sci. 2008 Jan 15; 264(1-2):140-4. Ovbiagele B, Buck BH, Liebeskind DS, Starkman S, Bang OY, Ali LK, Villablanca JP, Salamon N, Yun SW, Pineda S, Saver JL. PMID: 17854835.
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Association of higher serum calcium levels with smaller infarct volumes in acute ischemic stroke. Arch Neurol. 2007 Sep; 64(9):1287-91. Buck BH, Liebeskind DS, Saver JL, Bang OY, Starkman S, Ali LK, Kim D, Villablanca JP, Salamon N, Yun SW, Razinia T, Ovbiagele B. PMID: 17846267.
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Intra-arterial fibrinolysis for acute ischemic stroke: the message of melt. Stroke. 2007 Oct; 38(10):2627-8. Saver JL. PMID: 17702956.
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A case of acute ischemic stroke: optimizing management with penumbra and vessel imaging. Nat Clin Pract Neurol. 2007 Aug; 3(8):465-9. Buck BH, Saver JL. PMID: 17671524.
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Prediction of hemorrhagic transformation after recanalization therapy using T2*-permeability magnetic resonance imaging. Ann Neurol. 2007 Aug; 62(2):170-6. Bang OY, Buck BH, Saver JL, Alger JR, Yoon SR, Starkman S, Ovbiagele B, Kim D, Ali LK, Sanossian N, Jahan R, Duckwiler GR, Viñuela F, Salamon N, Villablanca JP, Liebeskind DS. PMID: 17683090.
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Hemorrhage after thrombolytic therapy for stroke: the clinically relevant number needed to harm. Stroke. 2007 Aug; 38(8):2279-83. Saver JL. PMID: 17641238.
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Leukocyte count and vascular risk in symptomatic intracranial atherosclerosis. Cerebrovasc Dis. 2007; 24(2-3):283-8. Ovbiagele B, Lynn MJ, Saver JL, Chimowitz MI, WASID Study Group. PMID: 17646693.
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FLAIR vascular hyperintensity may predict stroke after TIA. Clin Neurol Neurosurg. 2007 Sep; 109(7):617-9. Sanossian N, Ances BM, Shah SH, Kim D, Saver JL, Liebeskind DS. PMID: 17602831; PMCID: PMC4294545.
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A midlife stroke surge among women in the United States. Neurology. 2007 Nov 13; 69(20):1898-904. Towfighi A, Saver JL, Engelhardt R, Ovbiagele B. PMID: 17581944.
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Utility of urinalysis in discriminating cardioembolic stroke mechanism. Arch Neurol. 2007 May; 64(5):667-70. Viehman JA, Saver JL, Liebeskind DS, Starkman S, Ali LK, Buck B, Razinia T, Ovbiagele B. PMID: 17502465.
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Clinical impact of NXY-059 demonstrated in the SAINT I trial: derivation of number needed to treat for benefit over entire range of functional disability. Stroke. 2007 May; 38(5):1515-8. Saver JL. PMID: 17395871.
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Body mass index and hospital discharge outcomes after ischemic stroke. Arch Neurol. 2007 Mar; 64(3):388-91. Razinia T, Saver JL, Liebeskind DS, Ali LK, Buck B, Ovbiagele B. PMID: 17353382.
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Food and Drug Administration public hearing on the conduct of emergency clinical research: testimony of the American Stroke Association. Acad Emerg Med. 2007 Apr; 14(4):e57-8. Saver JL, American Stroke Association. PMID: 17322569.
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Intensive statin therapy after stroke or transient ischemic attack: a SPARCLing success? Stroke. 2007 Mar; 38(3):1110-2. Ovbiagele B, Saver JL. PMID: 17272769.
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The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke. 2007 Mar; 38(3):967-73. Rha JH, Saver JL. PMID: 17272772.
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High-density lipoprotein cholesterol: an emerging target for stroke treatment. Stroke. 2007 Mar; 38(3):1104-9. Sanossian N, Saver JL, Navab M, Ovbiagele B. PMID: 17255541.
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Confirmation of tPA treatment effect by baseline severity-adjusted end point reanalysis of the NINDS-tPA stroke trials. Stroke. 2007 Feb; 38(2):414-6. Saver JL, Yafeh B. PMID: 17234987.
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The ischemic stroke patient who worsens: new assessment and management approaches. Rev Neurol Dis. 2007; 4(2):85-91. Ali LK, Saver JL. PMID: 17609640.
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Deriving number-needed-to-treat and number-needed-to-harm from the SAINT I trial results. Stroke. 2007 Feb; 38(2):257; author reply 258. Saver JL. PMID: 17185635.
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Are racial differences in antihypertensive responsiveness reflected in usage after stroke? J Stroke Cerebrovasc Dis. 2006 Nov-Dec; 15(6):260-5. Ovbiagele B, Hills NK, Saver JL, Johnston SC, California Acute Stroke Prototype Registry Investigators. PMID: 17904085; PMCID: PMC2151475.
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Evidence of publication bias in reporting acute stroke clinical trials. Neurology. 2006 Sep 26; 67(6):973-9. Liebeskind DS, Kidwell CS, Sayre JW, Saver JL. PMID: 17000963.
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Thrombolysis in stroke: a medicolegal quagmire. Stroke. 2006 Nov; 37(11):2663; author reply 2664-5. Goldstein LB, Saver JL. PMID: 16990575.
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Aspirin and stroke severity. Stroke. 2006 Nov; 37(11):2660; author reply 2661. Sanossian N, Saver JL, Ovbiagele B. PMID: 16973927.
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Do high-density lipoprotein cholesterol levels influence stroke severity? J Stroke Cerebrovasc Dis. 2006 Sep-Oct; 15(5):187-9. Sanossian N, Saver JL, Kim D, Razinia T, Ovbiagele B. PMID: 17904074.
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Frequency and determinants of pneumonia and urinary tract infection during stroke hospitalization. J Stroke Cerebrovasc Dis. 2006 Sep-Oct; 15(5):209-13. Ovbiagele B, Hills NK, Saver JL, Johnston SC, California Acute Stroke Prototype Registry Investigators. PMID: 17904077; PMCID: PMC2720024.
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Frequency and determinants of nonpublication of research in the stroke literature. Stroke. 2006 Oct; 37(10):2588-92. Sanossian N, Ohanian AG, Saver JL, Kim LI, Ovbiagele B. PMID: 16931779.
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Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute stroke. Stroke. 2006 Oct; 37(10):2463-6. Neumann-Haefelin T, Hoelig S, Berkefeld J, Fiehler J, Gass A, Humpich M, Kastrup A, Kucinski T, Lecei O, Liebeskind DS, Rother J, Rosso C, Samson Y, Saver JL, Yan B, MR Stroke Group. PMID: 16931786.
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Achieving target cholesterol goals after stroke: is in-hospital statin initiation the key? Arch Neurol. 2006 Aug; 63(8):1081-3. Sanossian N, Saver JL, Liebeskind DS, Kim D, Razinia T, Ovbiagele B. PMID: 16908732.
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Lipid assessment and treatment patterns in hospitalized TIA and ischemic stroke patients. J Hosp Med. 2006 Jul; 1(4):214-20. Ovbiagele B, Hills NK, Saver JL, Johnston SC, CASPR Investigators. PMID: 17219502.
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Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke. 2006 Aug; 37(8):2086-93. Marder VJ, Chute DJ, Starkman S, Abolian AM, Kidwell C, Liebeskind D, Ovbiagele B, Vinuela F, Duckwiler G, Jahan R, Vespa PM, Selco S, Rajajee V, Kim D, Sanossian N, Saver JL. PMID: 16794209.
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Impact of metabolic syndrome on prognosis of symptomatic intracranial atherostenosis. Neurology. 2006 May 09; 66(9):1344-9. Ovbiagele B, Saver JL, Lynn MJ, Chimowitz M, WASID Study Group. PMID: 16682665.
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Cerebral white matter hyperintensities on MRI: Current concepts and therapeutic implications. Cerebrovasc Dis. 2006; 22(2-3):83-90. Ovbiagele B, Saver JL. PMID: 16685119.
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Does the Merci Retriever work? For. Stroke. 2006 May; 37(5):1340-1; discussion 1342-3. Saver JL. PMID: 16601216.
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Physician-investigator phone elicitation of consent in the field: a novel method to obtain explicit informed consent for prehospital clinical research. Prehosp Emerg Care. 2006 Apr-Jun; 10(2):182-5. Saver JL, Kidwell C, Eckstein M, Ovbiagele B, Starkman S, FAST-MAG Pilot Trial Investigators. PMID: 16531374.
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Secondary-prevention drug prescription in the very elderly after ischemic stroke or TIA. Neurology. 2006 Feb 14; 66(3):313-8. Ovbiagele B, Hills NK, Saver JL, Johnston SC. PMID: 16476928.
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The new standing guideline committee policy of the American Stroke Association Stroke Council. Stroke. 2006 Mar; 37(3):753. Saver JL, Goldstein LB. PMID: 16456116.
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Optimizing an evidence-based causative classification system for ischemic stroke. Ann Neurol. 2006 Feb; 59(2):434; author reply 434-5. Saver JL. PMID: 16437576.
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Effect of smoking status on outcome after acute ischemic stroke. Cerebrovasc Dis. 2006; 21(4):260-5. Ovbiagele B, Weir CJ, Saver JL, Muir KW, Lees KR, IMAGES Investigators. PMID: 16446540.
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Ensuring management of vascular risk factors after stroke. Rev Neurol Dis. 2006; 3(3):93-100. Ovbiagele B, Saver JL. PMID: 17047574.
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Can acute MRI predict outcome following transient ischemic attack and minor stroke? Nat Clin Pract Neurol. 2006 Jan; 2(1):14-5. Saver JL. PMID: 16932512.
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Time is brain--quantified. Stroke. 2006 Jan; 37(1):263-6. Saver JL. PMID: 16339467.
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Pericarditis associated with nickel hypersensitivity to the Amplatzer occluder device: a case report. Catheter Cardiovasc Interv. 2005 Nov; 66(3):424-6. Lai DW, Saver JL, Araujo JA, Reidl M, Tobis J. PMID: 16208708.
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Extending reperfusion therapy for acute ischemic stroke: emerging pharmacological, mechanical, and imaging strategies. Stroke. 2005 Oct; 36(10):2311-20. Molina CA, Saver JL. PMID: 16179577.
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Treatment adherence rates one year after initiation of a systematic hospital-based stroke prevention program. Cerebrovasc Dis. 2005; 20(4):280-2. Ovbiagele B, Kidwell CS, Selco S, Razinia T, Saver JL. PMID: 16127271.
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Use of multimodal MRI and novel endovascular therapies in a patient ineligible for intravenous tissue plasminogen activator. Stroke. 2005 Sep; 36(9):e77-9. Suzuki S, Kidwell CS, Starkman S, Saver JL, Duckwiler G, Vinuela F, Ovbiagele B. PMID: 16051897.
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Antihypertensive medications prescribed at discharge after an acute ischemic cerebrovascular event. Stroke. 2005 Sep; 36(9):1944-7. Ovbiagele B, Hills NK, Saver JL, Johnston SC. PMID: 16051895.
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The smoking-thrombolysis paradox and acute ischemic stroke. Neurology. 2005 Jul 26; 65(2):293-5. Ovbiagele B, Saver JL. PMID: 16043802.
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Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke. 2005 Jul; 36(7):1432-8. Smith WS, Sung G, Starkman S, Saver JL, Kidwell CS, Gobin YP, Lutsep HL, Nesbit GM, Grobelny T, Rymer MM, Silverman IE, Higashida RT, Budzik RF, Marks MP, MERCI Trial Investigators. PMID: 15961709.
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Prehospital care of the acute stroke patient. Tech Vasc Interv Radiol. 2005 Jun; 8(2):74-80. Rajajee V, Saver J. PMID: 16194754.
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Intracranial vascular stenosis and occlusive disease: evaluation with CT angiography, MR angiography, and digital subtraction angiography. AJNR Am J Neuroradiol. 2005 May; 26(5):1012-21. Bash S, Villablanca JP, Jahan R, Duckwiler G, Tillis M, Kidwell C, Saver J, Sayre J. PMID: 15891154; PMCID: PMC8158600.
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Withdrawal of warfarin prior to a surgical procedure: time to follow the guidelines? Cerebrovasc Dis. 2005; 19(5):337-42. Akopov SE, Suzuki S, Fredieu A, Kidwell CS, Saver JL, Cohen SN. PMID: 15818034.
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Expanding indications for statins in cerebral ischemia: a quantitative study. Arch Neurol. 2005 Jan; 62(1):67-72. Ovbiagele B, Kidwell CS, Saver JL. PMID: 15642851.
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Patent foramen ovale and stroke: what we do and don't know. Rev Neurol Dis. 2005; 2(1):1-7. Kim D, Saver JL. PMID: 16400296.
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Mitochondrial encephalomyopathy with lactic acidosis and stroke (MELAS). Rev Neurol Dis. 2005; 2(1):30-4. Matsumoto J, Saver JL, Brennan KC, Ringman JM. PMID: 16400302.
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Access to intra-arterial therapies for acute ischemic stroke: an analysis of the US population. AJNR Am J Neuroradiol. 2004 Nov-Dec; 25(10):1802-6. Suzuki S, Saver JL, Scott P, Jahan R, Duckwiler G, Starkman S, Su Y, Kidwell CS. PMID: 15569751; PMCID: PMC8148724.
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In-hospital initiation of secondary stroke prevention therapies yields high rates of adherence at follow-up. Stroke. 2004 Dec; 35(12):2879-83. Ovbiagele B, Saver JL, Fredieu A, Suzuki S, Selco S, Rajajee V, McNair N, Razinia T, Kidwell CS. PMID: 15514170.
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MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke. 2004 Dec; 35(12):2848-54. Gobin YP, Starkman S, Duckwiler GR, Grobelny T, Kidwell CS, Jahan R, Pile-Spellman J, Segal A, Vinuela F, Saver JL. PMID: 15514171.
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Comparison of MRI and CT for detection of acute intracerebral hemorrhage. JAMA. 2004 Oct 20; 292(15):1823-30. Kidwell CS, Chalela JA, Saver JL, Starkman S, Hill MD, Demchuk AM, Butman JA, Patronas N, Alger JR, Latour LL, Luby ML, Baird AE, Leary MC, Tremwel M, Ovbiagele B, Fredieu A, Suzuki S, Villablanca JP, Davis S, Dunn B, Todd JW, Ezzeddine MA, Haymore J, Lynch JK, Davis L, Warach S. PMID: 15494579.
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Evolving paradigms in neuroimaging of the ischemic penumbra. Stroke. 2004 Nov; 35(11 Suppl 1):2662-5. Kidwell CS, Alger JR, Saver JL. PMID: 15472112.
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Determining the appropriateness of selected surgical and medical management options in recurrent stroke prevention: a guideline for primary care physicians from the National Stroke Association work group on recurrent stroke prevention. J Stroke Cerebrovasc Dis. 2004 Sep-Oct; 13(5):196-207. Hanley D, Gorelick PB, Elliott WJ, Broder MS, Saver JL, Kidwell CS, Fagan SC, Wilson A, Lennihan L, Schwer WA, Rubenstein LZ, Crowell RM, Haines SJ, Lopez CC, Zorowitz R, Dubois RW. PMID: 17903976.
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Venous sinus thrombosis in a patient taking thalidomide. Cerebrovasc Dis. 2004; 18(2):175-7. Lenz RA, Saver J. PMID: 15256794.
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Number needed to treat estimates incorporating effects over the entire range of clinical outcomes: novel derivation method and application to thrombolytic therapy for acute stroke. Arch Neurol. 2004 Jul; 61(7):1066-70. Saver JL. PMID: 15262737.
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Comments on 'when to measure lipid profile after stroke'. Cerebrovasc Dis. 2005; 20(3):211. Ovbiagele B, Saver JL. PMID: 16103647.
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Hyperacute treatment initiation in neuroprotective agent stroke trials. J Stroke Cerebrovasc Dis. 2004 May-Jun; 13(3):109-12. Ferguson KN, Kidwell CS, Starkman S, Saver JL. PMID: 17903960.
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Neuroimaging in TIAs. Neurology. 2004 Apr 27; 62(8 Suppl 6):S22-5. Saver JL, Kidwell C. PMID: 15111653.
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Prehospital neuroprotective therapy for acute stroke: results of the Field Administration of Stroke Therapy-Magnesium (FAST-MAG) pilot trial. Stroke. 2004 May; 35(5):e106-8. Saver JL, Kidwell C, Eckstein M, Starkman S, FAST-MAG Pilot Trial Investigators. PMID: 15017009.
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Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies. Stroke. 2004 Feb; 35(2):e30-4. Ostrem JL, Saver JL, Alger JR, Starkman S, Leary MC, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Gobin YP, Vinuela F, Kidwell CS. PMID: 14739412.
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The Los Angeles Motor Scale (LAMS): a new measure to characterize stroke severity in the field. Prehosp Emerg Care. 2004 Jan-Mar; 8(1):46-50. Llanes JN, Kidwell CS, Starkman S, Leary MC, Eckstein M, Saver JL. PMID: 14691787.
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Potential Role of Neuroprotective Agents in the Treatment of Patients with Acute Ischemic Stroke. Curr Treat Options Cardiovasc Med. 2003 Dec; 5(6):441-449. Ovbiagele B, Kidwell CS, Starkman S, Saver JL. PMID: 14575621.
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Validation of computed tomographic middle cerebral artery "dot"sign: an angiographic correlation study. Stroke. 2003 Nov; 34(11):2636-40. Leary MC, Kidwell CS, Villablanca JP, Starkman S, Jahan R, Duckwiler GR, Gobin YP, Sykes S, Gough KJ, Ferguson K, Llanes JN, Masamed R, Tremwel M, Ovbiagele B, Vespa PM, Vinuela F, Saver JL. PMID: 14593125.
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Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging. Stroke. 2003 Nov; 34(11):2729-35. Kidwell CS, Alger JR, Saver JL. PMID: 14576370.
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Potential Role of Neuroprotective Agents in the Treatment of Patients with Acute Ischemic Stroke. Curr Treat Options Neurol. 2003 Sep; 5(5):367-375. Ovbiagele B, Kidwell CS, Starkman S, Saver JL. PMID: 12895399.
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A comparison of risk factors for recurrent TIA and stroke in patients diagnosed with TIA. Neurology. 2003 Jun 10; 60(11):1871; author reply 1871. Saver JL. PMID: 12796563.
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Beyond tissue plasminogen activator: mechanical intervention in acute stroke. Ann Emerg Med. 2003 Jun; 41(6):838-46. Leary MC, Saver JL, Gobin YP, Jahan R, Duckwiler GR, Vinuela F, Kidwell CS, Frazee J, Starkman S. PMID: 12764340.
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Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke. 2003 Jun; 34(6):1425-30. Shih LC, Saver JL, Alger JR, Starkman S, Leary MC, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Villablanca JP, Vespa PM, Kidwell CS. PMID: 12738899.
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Epidemiological impact in the United States of a tissue-based definition of transient ischemic attack. Stroke. 2003 Apr; 34(4):919-24. Ovbiagele B, Kidwell CS, Saver JL. PMID: 12637701.
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Neuroprotective agents for the treatment of acute ischemic stroke. Curr Neurol Neurosci Rep. 2003 Jan; 3(1):9-20. Ovbiagele B, Kidwell CS, Starkman S, Saver JL. PMID: 12507405.
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Annual incidence of first silent stroke in the United States: a preliminary estimate. Cerebrovasc Dis. 2003; 16(3):280-5. Leary MC, Saver JL. PMID: 12865617.
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Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol. 2002 Dec; 52(6):698-703. Kidwell CS, Saver JL, Starkman S, Duckwiler G, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Gobin YP, Vinuela F, Alger JR. PMID: 12447922.
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Transient ischemic attack--proposal for a new definition. N Engl J Med. 2002 Nov 21; 347(21):1713-6. Albers GW, Caplan LR, Easton JD, Fayad PB, Mohr JP, Saver JL, Sherman DG, TIA Working Group. PMID: 12444191.
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Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis. Stroke. 2002 Mar; 33(3):717-24. Kidwell CS, Saver JL, Carneado J, Sayre J, Starkman S, Duckwiler G, Gobin YP, Jahan R, Vespa P, Villablanca JP, Liebeskind DS, Vinuela F. PMID: 11872894.
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Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke. 2002 Jan; 33(1):95-8. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, Leary MC, Starkman S, Gobin YP, Jahan R, Vespa P, Liebeskind DS, Alger JR, Vinuela F. PMID: 11779895.
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Combination therapies and the theoretical limits of evidence-based medicine. Neuroepidemiology. 2001 May; 20(2):57-64. Saver JL, Kalafut M. PMID: 11359071.
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Poststroke seizures. Top Stroke Rehabil. 1994 Mar; 1(1):109-130. Saver JL, Roth EJ. PMID: 27680559.
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