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Catheter ablation of ventricular tachycardia via the coronary veins. Indian Pacing Electrophysiol J. 2026 Feb 23. Mori S, Hayase JH, Miyazaki Y, Yamagami S, Kawaji T, Shivkumar K. PMID: 41740724.
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Why The Polyvagal Theory Is Untenable: An international expert evaluation of the polyvagal theory and commentary upon Porges, S.W. (2025). Polyvagal theory: current status, clinical applications, and future directions. Clin. Neuropsychiatry, 22(3), 169-184. Clin Neuropsychiatry. 2026 Feb; 23(1):100-112. Grossman P, Ackland GL, Allen AM, Berntson GGB, Booth LC, Burghardt GM, Buron J, Dinets V, Doody JS, Dutschmann M, Farmer DGS, Fisher JP, Gourine AV, Joyner MJ, Karemaker JM, Khalsa SS, Lakatta EG, Leite CAC, Macefield VG, Machado BH, Machado RM, Menuet C, Mendelowitz D, Moraes DJA, Neuhuber W, Ottaviani MM, Paterson DJ, Paton JFP, Pellegrino PR, Ramchandra R, Shanks J, Schwaber JS, Shivkumar K, Spyer KM, Taylor EW, Taylor JA, Wang T, Yao ST, Zucker IH. PMID: 41768017; PMCID: PMC12937499.
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Amara Yad Image: Sectional View of the Left Ventricular Outflow Tract Viewed From the Superior Direction. J Am Coll Cardiol. 2026 Jan 27; 87(3):333-335. Goel NE, Shivkumar K. PMID: 41603511.
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Amara Yad Image: The 3-Chamber View-Inferomedial Segment. J Am Coll Cardiol. 2026 Jan 06; 87(1):117-119. Shivkumar K, Mori S. PMID: 41498475.
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Amara Yad Image: 2-Chamber View of the Left Heart-Medial Segment. J Am Coll Cardiol. 2025 Dec 23; 86(25):2720-2722. Shivkumar K, Mori S. PMID: 41432332.
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Amara Yad Image: 2-Chamber View of the Left Heart-Lateral Segment. J Am Coll Cardiol. 2025 Dec 16; 86(24):2535-2537. Shivkumar K, Mori S. PMID: 41579025.
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Neuropeptide Y regulation of L-type Ca 2+ channel activity is altered following chronic myocardial infarction. bioRxiv. 2025 Nov 29. Fiore CM, Agarwal SR, Elasoru SE, Ardell J, Ajijola O, Shivkumar K, Harvey RD. PMID: 41394738; PMCID: PMC12699418.
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Macroscopic and microscopic observations of a helix-fixation type leadless pacemaker 1 month after implantation. HeartRhythm Case Rep. 2026 Feb; 12(2):242-252. Miyazaki Y, Rimmer M, Bender AB, Hanna P, Hayase JH, Do DH, Xu S, Ajijola OA, Fishbein MC, Shivkumar K, Mori S. PMID: 41727305; PMCID: PMC12922532.
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Postmarket Data-Real World Safety Evaluation of Pulsed Field Ablation-and Beyond. J Am Coll Cardiol. 2026 Jan 20; 87(2):197-199. Dhruva SS, Kadakia KT, Shivkumar K. PMID: 41225724.
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Amara Yad Image: The 4-Chamber View-Inferior Segment. J Am Coll Cardiol. 2025 Nov 25; 86(21):2099-2101. Mori S, Shivkumar K. PMID: 41474206.
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Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: 12-Lead Electrocardiographic Anatomy. JACC Case Rep. 2026 Jan 07; 31(1):105998. Bradfield EP, Rimmer M, Miyazaki Y, Hanna P, Hayase JH, Do DH, Xu S, Yamagami S, Shivkumar K, Mori S. PMID: 41204941; PMCID: PMC12833672.
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Amara Yad Image: The Variable Relationship of the Coronary Sinus to the Mitral Annulus. J Am Coll Cardiol. 2025 Nov 11; 86(19):1754-1756. Shivkumar K. PMID: 41474203.
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Cardiac sympathetic denervation for refractory ventricular arrhythmias in patients with inherited cardiomyopathies. Heart Rhythm. 2025 Oct 31. Sarkar A, Pisciotti SL, Tapias C, Assis F, Tandri H, Wang J, Chrispin J, Syed F, Yanagawa J, Lee J, Bradfield JS, Shivkumar K, Saenz LC, Ajijola OA. PMID: 41177318.
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Amara Yad Image: The Relationship of the Pulmonary Artery to the Atrio-Caval Junction. J Am Coll Cardiol. 2025 Oct 28; 86(17):1456-1458. Shivkumar K. PMID: 41400302.
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Glia of the heart's nervous system. Nat Rev Neurosci. 2025 Dec; 26(12):737-748. Scherschel K, Wolf H, Ajijola OA, Shivkumar K, Lindner D, Gomez-Sanchez JA, Meyer C. PMID: 41107549.
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Adrenergic Hypersensitivity Drives Ventricular Arrhythmias Following Loss of Plexin-Mediated Cardiac Innervation. JACC Clin Electrophysiol. 2026 Jan; 12(1):44-58. Zhu C, Makita T, Lucero EY, Jyothidasan A, Patel R, Wang JJ, Cao Y, Rockman HA, Shivkumar K. PMID: 41042183; PMCID: PMC12614344.
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Methadone Blockade of Inward Rectifier Potassium Current Promotes Both Early and Delayed Repolarization Arrhythmias: Mechanistic Insights From Computational Modeling. J Am Heart Assoc. 2025 Oct 07; 14(19):e042201. Zhang Z, Green JT, Haigney MC, Walker P, Shivkumar K, Garfinkel A, Qu Z. PMID: 40996098; PMCID: PMC12684491.
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Volume Rendering-Based Phrenic Nerve/Pericardiophrenic Bundle Identification Using Cardiac Computed Tomography. JACC Case Rep. 2025 Sep 10; 30(27):104947. Aoyama D, Rimmer M, Miyazaki Y, Izawa Y, Nishii T, Shivkumar K, Mori S. PMID: 40940115; PMCID: PMC12789753.
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Three-Dimensional Printing of the Human Pericardium to Facilitate Understanding of the Pericardial Reflections, Recesses, and Sinuses. Circ Cardiovasc Imaging. 2025 Dec; 18(12):e018410. Miyazaki Y, Rimmer M, Peacock WJ, Xu S, Shivkumar K, Mori S. PMID: 40859840; PMCID: PMC12667300.
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Adrenergic Hypersensitivity Drives Ventricular Arrhythmias Following Loss of Plexin-Mediated Cardiac Innervation. bioRxiv. 2025 Aug 26. Zhu C, Makita T, Lucero EY, Jyothidasan A, Patel R, Wang JJ, Cao Y, Rockman HA, Shivkumar K. PMID: 40501743; PMCID: PMC12154780.
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Right stellate ganglion stimulation modulates arrhythmogenesis in acute left lateral ventricular ischaemia. Cardiovasc Res. 2025 Aug 14; 121(9):1385-1391. Hadaya J, Boukens BJD, Janse MJ, Cha S, Dajani AH, Challita R, Coronel R, Ardell JL, Shivkumar K, Meijborg VMF. PMID: 40658729; PMCID: PMC12352303.
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Ventricular Tachycardia Predicts All-Cause Mortality and Nonsudden Cardiac Death in Nonischemic Cardiomyopathy. JACC Adv. 2025 Sep; 4(9):102063. Omara S, Jensen TN, Koeber L, Thune JJ, Pehrson S, Mertens B, Tedrow UB, Hindricks G, Ebert M, Carbucicchio C, Berruezo A, Vaseghi M, Shivkumar K, Deneke T, Wijnmaalen AP, Stevenson WG, Nielsen JC, Zeppenfeld K. PMID: 40811878; PMCID: PMC12362670.
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Amara Yad Image: The Relationship of the Atria to the Base of the Heart and the Great Vessels. J Am Coll Cardiol. 2025 Aug 19; 86(7):556-558. Shivkumar K. PMID: 41384681.
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Seeing the Forest for the Trees: A Novel Marker for the His-Purkinje System. JACC Clin Electrophysiol. 2025 Aug; 11(8):1736-1737. Hanna P, Shivkumar K. PMID: 40772890.
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Three-Dimensional Magnetic Resonance Imaging of the Human Stellate Ganglion. Clin Anat. 2025 Jul 23. Nakajo M, Mori S, Nakayama H, Yoshiura T, Xu S, Rimmer M, Sato T, Sato M, Malik V, Salamon N, Zhong X, Nguyen KL, Finn JP, Peacock WJ, Shivkumar K. PMID: 40698794.
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Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Subclavian Artery and Vein. JACC Case Rep. 2025 Jul 02; 30(17):103896. Sato T, Mori S, Do DH, Rimmer M, Xu S, Yoshioka A, Yamagami S, Ishibashi K, Kusano K, Peacock WJ, Shivkumar K. PMID: 40615188; PMCID: PMC12441354.
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Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Left Atrial Appendage. JACC Case Rep. 2025 Jul 16; 30(19):104119. Macias IM, Mori S, Sato T, Miyazaki Y, Rimmer M, Hanna P, Moussa ID, Shivkumar K. PMID: 40576592; PMCID: PMC12441441.
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Pre-procedural simulation of the right atrium to left ventricle puncture through the inferoseptal process using cardiac computed tomography. HeartRhythm Case Rep. 2025 Aug; 11(8):767-775. Miyazaki Y, Mori S, Bertog S, Shivkumar K, Tholakanahalli V. PMID: 40896679; PMCID: PMC12399163.
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Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy. Anat Rec (Hoboken). 2026 Feb; 309(2):417-450. Hanna P, Hoover DB, Kirkland LG, Smith EH, Poston MD, Peirce SG, Garbe CG, Phillips TK, Cha S, Mori S, Brennan JA, Armour JA, Rytkin E, Efimov IR, Ajijola OA, Ardell JL, Shivkumar K. PMID: 40365781; PMCID: PMC12353864.
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Redefining respiratory sinus arrhythmia as respiratory heart rate variability: an international Expert Recommendation for terminological clarity. Nat Rev Cardiol. 2025 12; 22(12):978-984. Menuet C, Ben-Tal A, Linossier A, Allen AM, Machado BH, Moraes DJA, Farmer DGS, Paterson DJ, Mendelowitz D, Lakatta EG, Taylor EW, Ackland GL, Zucker IH, Fisher JP, Schwaber JS, Shanks J, Paton JFR, Buron J, Spyer KM, Shivkumar K, Dutschmann M, Joyner MJ, Herring N, Grossman P, McAllen RM, Ramchandra R, Yao ST, Ritz T, Gourine AV. PMID: 40328963.
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Proactive Electrophysiological Mapping and Ablation to Prevent Ventricular Tachycardia in Repaired Tetralogy of Fallot. J Am Coll Cardiol. 2025 May 06; 85(17):1706-1708. Meyer C, Shivkumar K. PMID: 40306843.
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Cardioneural Ablation: A New Hope. JACC Clin Electrophysiol. 2025 Aug; 11(8):1696-1698. Ajijola OA, Shivkumar K. PMID: 40392663.
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In-Situ Observation of Incomplete Left Main Trunk Obstruction After Valve-in-Valve Transcatheter Aortic Valve Implantation. Circ J. 2025 Apr 25; 89(5):654-655. Sato T, Moussa ID, Shivkumar K, Mori S. PMID: 40189241.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC Heart Fail. 2025 Apr; 13(4):671-672. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40204390.
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Epicardial ventricular arrhythmia ablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society, the Asian Pacific Heart Rhythm Society, the Latin American Heart Rhythm Society, and the Canadian Heart Rhythm Society. Europace. 2025 Mar 28; 27(4). Arya A, Di Biase L, Bazán V, Berruezo A, d'Avila A, Della Bella P, Enriquez A, Hocini M, Kautzner J, Pak HN, Stevenson WG, Zeppenfeld K, Sepehri Shamloo A, Meyer C, de Chillou C, Deneke T, de Riva M, Porta-Sanchez A, Sapp J, Schmidt B, Shivkumar K, Sommer P, Soejima K, Supple GE, Wilde A, Zucchelli G. PMID: 40163515; PMCID: PMC11956854.
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Preface Editorial for Special Issue Dedicated to Jeffrey L. Ardell (1952-2025) Cardiac Neurobiology: Concepts to Clinic. J Physiol. 2025 Mar; 603(7):1683-1686. Paterson DJ, Shivkumar K. PMID: 40100704.
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The vestigial fold in humans: Characterization of a potential novel target for selective cardiac sympathetic denervation. Heart Rhythm. 2025 Oct; 22(10):2711-2721. Sato T, Fishbein MC, Hanna P, Ajijola OA, Shivkumar K, Mori S. PMID: 40107399.
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Clinical neurocardiology: defining the value of neuroscience-based cardiovascular therapeutics - 2024 update. J Physiol. 2025 Mar; 603(7):1781-1839. Ajijola OA, Aksu T, Arora R, Biaggioni I, Chen PS, De Ferrari G, Dusi V, Fudim M, Goldberger JJ, Green AL, Herring N, Khalsa SS, Kumar R, Lakatta E, Mehra R, Meyer C, Po S, Stavrakis S, Somers VK, Tan AY, Valderrabano M, Shivkumar K. PMID: 40056025.
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Amara Yad Image: Myocardial Scar. J Am Coll Cardiol. 2025 Feb 25; 85(7):782-783. Mori S, Fishbein MC, Shivkumar K. PMID: 39971411.
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Rare bilateral anatomical variation of the lateral thoracic artery: duplicated arteries with unique origins and pathways. Surg Radiol Anat. 2025 Feb 18; 47(1):80. Rimmer M, J Peacock W, Shivkumar K, Mori S. PMID: 39966115; PMCID: PMC11836202.
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Amara Yad Image: Cardiac Fibrous Skeleton-The Aortic Root, Tricuspid Valve, and the Membranous Septum. J Am Coll Cardiol. 2025 Feb 18; 85(6):655-656. Shivkumar K. PMID: 39939045.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC Clin Electrophysiol. 2025 Apr; 11(4):878-879. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40306897.
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Articulating the JACC Journals' Direction in Times of Global Change. J Am Coll Cardiol. 2025 Apr 15; 85(14):1515-1516. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40204381.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC Asia. 2025 Apr; 5(4):607-608. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40180556; PMCID: PMC12081218.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC Cardiovasc Interv. 2025 Apr 28; 18(8):1087-1088. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40306847.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC Case Rep. 2025 Apr 16; 30(8):103416. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40250899; PMCID: PMC12046986.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC Adv. 2025 Apr; 4(4):101639. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40280704; PMCID: PMC12139216.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC Cardiovasc Imaging. 2025 Apr; 18(4):522-523. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40204423.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC CardioOncol. 2025 Apr; 7(3):322-323. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40246401; PMCID: PMC12046888.
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Articulating the JACC Journals' Direction in Times of Global Change. JACC Basic Transl Sci. 2025 Jul; 10(7):101241. Krumholz HM, Bozkurt B, Chandrashekhar Y, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Tang GHL, Wang J. PMID: 40738515; PMCID: PMC12434194.
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Amara Yad Image: Cardiac Fibrous Skeleton. J Am Coll Cardiol. 2025 Feb 11; 85(5):560-561. Shivkumar K. PMID: 39909685.
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Amara Yad Image: The Mitral Valve, Aortic Root, and Aortomitral Continuity. J Am Coll Cardiol. 2025 Feb 04; 85(4):389-390. Shivkumar K. PMID: 39880547.
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Moving from voltage mapping to scar mapping using novel "near-field" metrics. Heart Rhythm. 2025 Aug; 22(8):2099-2110. Hayase JH, Jain R, Lux R, Mori S, Ajijola OA, Shivkumar K, Bradfield JS. PMID: 39894137.
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The Amara Yad Project: A New Resource for Cardiac Anatomy. J Am Coll Cardiol. 2025 Jan 28; 85(3):292-294. Shivkumar K, Krumholz HM. PMID: 39843031.
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Amara Yad Image: The Tricuspid Valve. J Am Coll Cardiol. 2025 Jan 28; 85(3):295-296. Shivkumar K. PMID: 39843032.
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Tricuspid Transcatheter Edge-to-Edge Repair: An Approach Whose Time Has Come for Electrophysiology. JACC Clin Electrophysiol. 2025 May; 11(5):1021-1023. Aboulhosn J, Shivkumar K. PMID: 39903154.
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Age-Related Ventricular Tachycardia Substrate Characteristics for Repaired Tetralogy of Fallot Before Transcatheter Pulmonary Valve Placement. JACC Clin Electrophysiol. 2025 Mar; 11(3):551-562. Moore JP, Waldmann V, Bessière F, Babouri N, Cohen MI, O'Leary ET, Patel NS, Nazer B, Tan W, Fish FA, Dalal AS, Mariucci E, Tan RB, Lloyd MS, McLeod CJ, Anderson CC, Kanter RJ, Johnson BV, Wang B, Chang PM, Newlon CA, Su J, Shannon KM, Bradfield JS, Shivkumar K, Aboulhosn JA, Khairy P. PMID: 39818670.
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Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Atrioventricular Node Artery. JACC Case Rep. 2025 Jan 15; 30(2):102753. Esrailian AJ, Mori S, Sato T, Izawa Y, Shivkumar K. PMID: 39886401; PMCID: PMC11775805.
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Electrocardiographic Characteristics and Ablation Outcomes Associated With Para-Hisian Ventricular Arrhythmias. JACC Asia. 2025 Feb; 5(2):299-312. Nair A, Shroff JP, Tuan LQ, Tokich A, Raja DC, Mehta A, Abhayaratna WP, Sanders P, Marchlinski FE, Shivkumar K, Pathak RK. PMID: 39967222; PMCID: PMC11840233.
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Sudden Cardiac Death: Insights From Transcriptomics. JACC Clin Electrophysiol. 2025 Jan; 11(1):156-157. Rajendran PS, Shivkumar K. PMID: 39880540.
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Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Femoral Artery and Vein: Part 1. JACC Case Rep. 2024 Dec 04; 29(23):102807. Sato T, Mori S, Hanna P, Bender A, Hayase J, Xu S, Yoshioka A, Yamagami S, Toba T, Izawa Y, Shivkumar K. PMID: 39691319; PMCID: PMC11646876.
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Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Femoral Artery and Vein: Part 2. JACC Case Rep. 2024 Dec 04; 29(23):102800. Sato T, Mori S, Hanna P, Bender A, Hayase J, Xu S, Yoshioka A, Yamagami S, Toba T, Izawa Y, Shivkumar K. PMID: 39691332; PMCID: PMC11646903.
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Ultrastructure and cardiac impulse propagation: scaling up from microscopic to macroscopic conduction. J Physiol. 2025 Mar; 603(7):1887-1901. Qu Z, Hanna P, Ajijola OA, Garfinkel A, Shivkumar K. PMID: 39612369; PMCID: PMC11955865.
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The Rebirth of Intraoperative Electrophysiological Mapping for Complex Congenital Heart Disease. J Am Coll Cardiol. 2024 Nov 19; 84(21):2113-2115. Moore JP, Shivkumar K. PMID: 39537251.
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A Bold New Era of Collaboration: JACC and JACC Clinical Electrophysiology Unite. J Am Coll Cardiol. 2024 Nov 19; 84(21):2148-2149. Shivkumar K, Krumholz HM. PMID: 39537253.
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Bioelectronic block of stellate ganglia mitigates pacing-induced heterogeneous release of catecholamine and neuropeptide Y in the infarcted pig heart. J Physiol. 2025 Mar; 603(7):2071-2088. Vrabec T, Bender S, Chan SA, Cha S, Haridas S, Hanna P, Ajijola OA, Shivkumar K, Smith C, Ardell JL. PMID: 39557601; PMCID: PMC11955864.
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Comparative specialization of intrinsic cardiac neurons in humans, mice and pigs. J Physiol. 2025 Mar; 603(7):2043-2070. Tompkins JD, Hoover DB, Havton LA, Patel JC, Cho Y, Smith EH, Biscola NP, Ajijola OA, Shivkumar K, Ardell JL. PMID: 39513933; PMCID: PMC11957936.
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Prevalence of frequent premature ventricular contractions and left-ventricular systolic dysfunction in patients receiving Holter monitoring. J Cardiovasc Electrophysiol. 2025 Jan; 36(1):54-61. Torrado J, Sima A, Comstuck C, Kaszala K, Tan A, Koneru J, Frankel DS, Marchlinski F, Kowalski M, Sharma P, Gerstenfeld EP, Vaseghi M, Shivkumar K, Malhotra R, Morillo C, Ellenbogen KA, Huizar JF. PMID: 39445764; PMCID: PMC11727014.
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Towards spatially selective efferent neuromodulation: anatomical and functional organization of cardiac fibres in the porcine cervical vagus nerve. J Physiol. 2025 Mar; 603(7):1983-2004. Thompson N, Ravagli E, Mastitskaya S, Challita R, Hadaya J, Iacoviello F, Idil AS, Shearing PR, Ajijola OA, Ardell JL, Shivkumar K, Holder D, Aristovich K. PMID: 39183636; PMCID: PMC11955868.
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Idiopathic Ventricular Fibrillation: Truly Idiopathic or Are We Missing Occult Pathology? JACC Clin Electrophysiol. 2024 Sep; 10(9):1995-1997. Do DH, Shivkumar K. PMID: 39066780.
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Procedural and Intermediate-term Results of the Electroanatomical-guided Cardioneuroablation for the Treatment of Supra-Hisian Second- or Advanced-degree Atrioventricular Block: the PIRECNA multicentre registry. Europace. 2024 Jul 02; 26(7). Aksu T, Piotrowski R, Tung R, De Potter T, Markman TM, du Fay de Lavallaz J, Rekvava R, Alyesh D, Joza JE, Badertscher P, Do DH, Bradfield JS, Upadhyay G, Sood N, Sharma PS, Guler TE, Gul EE, Kumar V, Koektuerk B, Dal Forno ARJ, Woods CE, Rav-Acha M, Valeriano C, Enriquez A, Sundaram S, Glikson M, d'Avila A, Shivkumar K, Kulakowski P, Huang HD. PMID: 38954426; PMCID: PMC11218561.
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Osteopontin stabilization and collagen containment slows amorphous calcium phosphate transformation during human aortic valve leaflet calcification. Sci Rep. 2024 05 28; 14(1):12222. Sivaguru M, Mori S, Fouke KW, Ajijola OA, Shivkumar K, Samuel AZ, Bhargava R, Fouke BW. PMID: 38806601; PMCID: PMC11133482.
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Underexpansion and Neoleaflet Bending Caused by Transcatheter Valve-in-Valve Mismatch. JACC Cardiovasc Interv. 2024 Jun 10; 17(11):1400-1403. Sato T, Moussa ID, Ajijola OA, Shivkumar K, Mori S. PMID: 38703148.
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Rate of Change of Initial Intrinsicoid Deflection Predicts Endocardial Versus Epicardial Ventricular Tachycardia. JACC Clin Electrophysiol. 2024 Jun; 10(6):1150-1160. Prisco AR, Hayase J, Olson M, Brigham RC, Ramirez DA, Iaizzo PA, Shivkumar K, Bradfield J, Tholakanahalli VN. PMID: 38703167.
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Comparative specialization of intrinsic cardiac neurons in humans, mice, and pigs. bioRxiv. 2024 Apr 08. Tompkins JD, Hoover DB, Havton LA, Patel JC, Cho Y, Smith EH, Biscola NP, Ajijola OA, Shivkumar K, Ardell JL. PMID: 38645175; PMCID: PMC11030249.
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Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry. J Interv Card Electrophysiol. 2025 Mar; 68(2):183-191. Aksu T, Tung R, De Potter T, Markman TM, Santangeli P, du Fay de Lavallaz J, Winterfield JR, Baykaner T, Alyesh D, Joza JE, Gopinathannair R, Badertscher P, Do DH, Hussein A, Osorio J, Dewland T, Perino A, Rodgers AJ, DeSimone C, Alfie A, Atwater BD, Singh D, Kumar K, Salcedo J, Bradfield JS, Upadhyay G, Sood N, Sharma PS, Gautam S, Kumar V, Forno ARJD, Woods CE, Rav-Acha M, Valeriano C, Kapur S, Enriquez A, Sundaram S, Glikson M, Gerstenfeld E, Piccini J, Tzou WS, Sauer W, d'Avila A, Shivkumar K, Huang HD. PMID: 38499825; PMCID: PMC12064083.
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Stellate ganglion blockade for the management of ventricular arrhythmia storm. Eur Heart J. 2024 Mar 07; 45(10):834-836. Malik V, Shivkumar K. PMID: 38366239; PMCID: PMC10919926.
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Multidetector Computed Tomography Assessment of Anatomical Ventricular Tachycardia Isthmuses in Repaired Tetralogy of Fallot. JACC Clin Electrophysiol. 2024 May; 10(5):857-866. Moore JP, Su J, Shannon KM, Perens GS, Newlon C, Bradfield JS, Shivkumar K. PMID: 38456860.
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Anatomical and functional organization of cardiac fibers in the porcine cervical vagus nerve allows spatially selective efferent neuromodulation. bioRxiv. 2024 Mar 04. Thompson N, Ravagli E, Mastitskaya S, Challita R, Hadaya J, Iacoviello F, Shah Idil A, Shearing PR, Ajijola OA, Ardell JL, Shivkumar K, Holder D, Aristovich K. PMID: 38260584; PMCID: PMC10802425.
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Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Interleaflet Triangle. JACC Clin Electrophysiol. 2024 Apr; 10(4):801-807. Sato T, Bradfield JS, Shivkumar K, Mori S. PMID: 38430089.
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Long-Term Outcomes of Cardiac Resynchronization Therapy in Patients With Repaired Tetralogy of Fallot: A Multicenter Study. Circ Arrhythm Electrophysiol. 2024 03; 17(3):e012363. Ramdat Misier NL, Moore JP, Nguyen HH, Lloyd MS, Dubin AM, Mah DY, Czosek RJ, Khairy P, Chang PM, Nielsen JC, Aydin A, Pilcher TA, O'Leary ET, Shivkumar K, de Groot NMS. PMID: 38344811.
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Bioelectronics for neurocardiology: diagnosis and therapeutics. Eur Heart J. 2023 Dec 07; 44(46):4822-4825. Paterson DJ, Shivkumar K, Bioelectronics for Neurocardiology Consortium . PMID: 37949823.
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Are device-detected atrial high-rate episodes a risk marker for stroke? Nat Cardiovasc Res. 2023 12; 2(12):1097-1098. Hanna P, Buch E, Shivkumar K. PMID: 39196145; PMCID: PMC11908076.
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Comprehensive Anatomy of the Summit of the Left Ventricle. JACC Clin Electrophysiol. 2024 01; 10(1):168-184. Mori S, Bradfield JS, Fukuzawa K, Shivkumar K. PMID: 37999670.
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Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Sinus Node Artery. JACC Case Rep. 2023 Dec 20; 28:102124. Esrailian DL, Mori S, Shivkumar K. PMID: 38204525; PMCID: PMC10774828.
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Distribution and morphology of calcitonin gene-related peptide (CGRP) innervation in flat mounts of whole rat atria and ventricles. Auton Neurosci. 2024 02; 251:103127. Chen J, Bendowski KT, Bizanti A, Zhang Y, Ma J, Hoover DB, Gozal D, Shivkumar K, Cheng ZJ. PMID: 38211380; PMCID: PMC11639590.
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Demonstration of feasibility and technique of transesophageal endoscopic epicardial access in a porcine model. IGIE. 2023 Dec; 2(4):418-423. Weitzner ZN, Cha S, Challita R, Ajijola O, Mori S, Shivkumar K, Dutson E, Sedarat A. PMID: 41646068; PMCID: PMC12850758.
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Intermediate Accessory Papillary Muscle: An Anatomic Variant of Interest for Transcatheter Edge-to-Edge Mitral Valve Repair. Circ Cardiovasc Imaging. 2023 10; 16(10):e015151. Sato T, Moussa ID, Hanna P, Shivkumar K, Mori S. PMID: 37847764; PMCID: PMC10584364.
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Sympathetic innervation of the supraclavicular brown adipose tissue: A detailed anatomical study. PLoS One. 2023; 18(10):e0290455. Mori S, Beyer RS, Bernardes de Souza B, Sorg JM, Hoover DB, Sacks HS, Fishbein MC, Chang G, Peacock WJ, St John MA, Law J, Symonds ME, Ajijola OA, Shivkumar K, Srikanthan P. PMID: 37792692; PMCID: PMC10550181.
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Cryothermal energy demonstrates shorter ablation time and lower complication rates compared with radiofrequency in surgical hybrid ablation for recurrent ventricular tachycardia. Heart Rhythm. 2023 12; 20(12):1708-1717. Chung WH, Hayase J, Davies MJ, Do DH, Sorg JM, Ajijola OA, Buch EF, Boyle NG, Shivkumar K, Bradfield JS. PMID: 37659454.
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Insights Into Interaction Between Clip Device and the Mitral Valve Apparatus in the Human Heart. JACC Case Rep. 2023 Sep 20; 22:101999. Sato T, Moussa ID, Hanna P, Shivkumar K, Mori S. PMID: 37790766; PMCID: PMC10544422.
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Cardiac Conduction System Pacing: A Comprehensive Update. JACC Clin Electrophysiol. 2023 11; 9(11):2358-2387. Vijayaraman P, Chelu MG, Curila K, Dandamudi G, Herweg B, Mori S, Jastrzebski M, Sharma PS, Shivkumar K, Tung R, Upadhyay G, Vernooy K, Welter-Frost A, Whinnett Z, Zanon F, Ellenbogen KA. PMID: 37589646.
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Ischemia-induced ventricular proarrhythmia and cardiovascular autonomic dysreflexia after cardioneuroablation. Heart Rhythm. 2023 11; 20(11):1534-1545. Chung WH, Masuyama K, Challita R, Hayase J, Mori S, Cha S, Bradfield JS, Ardell JL, Shivkumar K, Ajijola OA. PMID: 37562487.
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Rationale and Design of the Multicenter Catheter Ablation of Ventricular Tachycardia Before Transcatheter Pulmonary Valve Replacement in Repaired Tetralogy of Fallot Study. Am J Cardiol. 2023 10 01; 204:14-21. Moore JP, Aboulhosn JA, Zeppenfeld K, Waldmann V, Bessière F, Blom NA, Combes N, Fish FA, McLeod CJ, Kanter RJ, Tan W, Patel N, von Alvensleben JC, Kamp A, Lloyd MS, Anderson CC, Tan RB, Mariucci E, Levi DS, Salem M, Shivkumar K, Khairy P. PMID: 37536198.
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Photogrammetry of Perfusion-Fixed Heart: Innovative Approach to Study 3-Dimensional Cardiac Anatomy. JACC Clin Electrophysiol. 2023 10; 9(10):2197-2216. Sato T, Hanna P, Ajijola OA, Shivkumar K, Mori S. PMID: 37516938.
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Design and characteristics of the prophylactic intra-operative ventricular arrhythmia ablation in high-risk LVAD candidates (PIVATAL) trial. Ann Noninvasive Electrocardiol. 2023 09; 28(5):e13073. Huang DT, Gosev I, Wood KL, Vidula H, Stevenson W, Marchlinski F, Supple G, Zalawadiya SK, Weiss JP, Tung R, Tzou WS, Moss JD, Kancharla K, Chaudhry SP, Patel PJ, Khan AM, Schuger C, Rozen G, Kiernan MS, Couper GS, Leacche M, Molina EJ, Shah AD, Lloyd M, Sroubek J, Soltesz E, Shivkumar K, White C, Tankut S, Johnson BA, McNitt S, Kutyifa V, Zareba W, Goldenberg I. PMID: 37515396; PMCID: PMC10475893.
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Photogrammetry of Perfusion-Fixed Heart: Innovative Approach to Study 3-Dimensional Cardiac Anatomy. JACC Case Rep. 2023 Sep 06; 21:101937. Sato T, Hanna P, Ajijola OA, Shivkumar K, Mori S. PMID: 37719294; PMCID: PMC10500340.
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Linear epicardial cryoablation effects in a porcine model: Lesion characteristics and vascular risk. J Cardiovasc Electrophysiol. 2023 09; 34(9):1878-1884. Hayase J, Fishbein G, Rerkpichaisuth V, Chung WH, Ajijola O, Shivkumar K, Bradfield JS. PMID: 37473428.
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Vagal Nerve Stimulation Reduces Ventricular Arrhythmias and Mitigates Adverse Neural Cardiac Remodeling Post-Myocardial Infarction. JACC Basic Transl Sci. 2023 Sep; 8(9):1100-1118. Hadaya J, Dajani AH, Cha S, Hanna P, Challita R, Hoover DB, Ajijola OA, Shivkumar K, Ardell JL. PMID: 37791302; PMCID: PMC10543930.
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Outcomes in orthotopic heart transplantation following pacemaker implantation. Pacing Clin Electrophysiol. 2023 07; 46(7):583-591. Do DH, Bailey KL, Beyer R, Neubuerger S, Bradfield J, Shivkumar K, Nsair A, Boyle NG. PMID: 37221975; PMCID: PMC10524466.
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Transcatheter Aortic Valve Replacement Guided by Preprocedural Simulation of Fluoroscopic Location of the Membranous Septum. JACC Case Rep. 2023 Jun 21; 16:101888. Mori S, Aksoy O, Do DH, Dave RH, Shivkumar K. PMID: 37396330; PMCID: PMC10313484.
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Topographical mapping of catecholaminergic axon innervation in the flat-mounts of the mouse atria: a quantitative analysis. Sci Rep. 2023 04 07; 13(1):4850. Zhang Y, Bizanti A, Harden SW, Chen J, Bendowski K, Hoover DB, Gozal D, Shivkumar K, Heal M, Tappan S, Cheng ZJ. PMID: 37029119; PMCID: PMC10082215.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC Heart Fail. 2023 04; 11(4):487-489. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 36939659.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC Cardiovasc Imaging. 2023 04; 16(4):572-574. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 36939663.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC CardioOncol. 2023 Apr; 5(2):275-277. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 37144104; PMCID: PMC10152189.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC Asia. 2023 Apr; 3(2):317-319. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 37181383; PMCID: PMC10167500.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC Case Rep. 2023 May 03; 13:101806. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 37153478; PMCID: PMC10157143.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC Clin Electrophysiol. 2023 04; 9(4):607-609. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 36939662.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. J Am Coll Cardiol. 2023 04 18; 81(15):1543-1545. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 36935264.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC Cardiovasc Interv. 2023 04 10; 16(7):881-883. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 36935255.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC Basic Transl Sci. 2023 May; 8(5):596-598. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 37325406; PMCID: PMC10264704.
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JACC Journals' Pathway Forward With AI Tools: The Future Is Now. JACC Adv. 2023 Mar; 2(2):100296. Fuster V, Bozkurt B, Chandrashekhar Y, Grapsa J, Ky B, Mann DL, Moliterno DJ, Shivkumar K, Silversides CK, Turco JV, Wang J. PMID: 38938321; PMCID: PMC11198586.
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Ventricular Parasystole in Cardiomyopathy Patients: A Link Between His-Purkinje System Damage and Ventricular Fibrillation. JACC Clin Electrophysiol. 2023 07; 9(7 Pt 1):936-948. Do DH, O'Meara K, Lee J, Meyer S, Hanna P, Mori S, Fishbein MC, Boyle NG, Elizari MV, Bradfield JS, Shivkumar K. PMID: 37438043.
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The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine. Semin Cell Dev Biol. 2024 03 15; 156:190-200. Rajendran PS, Hadaya J, Khalsa SS, Yu C, Chang R, Shivkumar K. PMID: 36641366; PMCID: PMC10336178.
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Catecholaminergic axon innervation and morphology in flat-mounts of atria and ventricles of mice. J Comp Neurol. 2023 04; 531(5):596-617. Bizanti A, Zhang Y, Harden SW, Chen J, Hoover DB, Gozal D, Shivkumar K, Cheng ZJ. PMID: 36591925; PMCID: PMC10499115.
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Cardiac fibrosis in three dimensions - mechanistic insights into arrhythmic risk due to hypertrophy. J Physiol. 2023 01; 601(2):249-250. Shivkumar K, Qu Z, Harvey R. PMID: 36511350; PMCID: PMC9846953.
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Revisiting the Anatomy of the Left Ventricular Summit. Card Electrophysiol Clin. 2023 03; 15(1):1-8. Mori S, Hayase J, Sridharan A, Fukuzawa K, Shivkumar K, Bradfield JS. PMID: 36774131.
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Clinical predictors and implications of cardiac inflammation detected on positron emission tomography (PET) in patients referred for premature ventricular complex (PVC) ablation. J Interv Card Electrophysiol. 2023 Aug; 66(5):1253-1263. Chung WH, Hayase J, Do DH, Dixit N, Ajijola O, Buch E, Boyle N, Shivkumar K, Bradfield JS. PMID: 36510109.
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CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization. Nature. 2023 01; 613(7942):160-168. Qian K, Tol MJ, Wu J, Uchiyama LF, Xiao X, Cui L, Bedard AH, Weston TA, Rajendran PS, Vergnes L, Shimanaka Y, Yin Y, Jami-Alahmadi Y, Cohn W, Bajar BT, Lin CH, Jin B, DeNardo LA, Black DL, Whitelegge JP, Wohlschlegel JA, Reue K, Shivkumar K, Chen FJ, Young SG, Li P, Tontonoz P. PMID: 36477540; PMCID: PMC9995219.
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Cardiac Resynchronization Therapy for Adult Patients With a Failing Systemic Right Ventricle: A Multicenter Study. J Am Heart Assoc. 2022 11 15; 11(22):e025121. Kharbanda RK, Moore JP, Lloyd MS, Galotti R, Bogers AJJC, Taverne YJHJ, Madhavan M, McLeod CJ, Dubin AM, Mah DY, Chang PM, Kamp AN, Nielsen JC, Aydin A, Tanel RE, Shah MJ, Pilcher T, Evertz R, Khairy P, Tan RB, Czosek RJ, Shivkumar K, de Groot NMS. PMID: 36346046; PMCID: PMC9750073.
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Single-Cell RNA-Seq Identifies Dynamic Cardiac Transition Program from ADCs Induced by Leukemia Inhibitory Factor. Stem Cells. 2022 10 21; 40(10):932-948. Yao J, Ma F, Zhang L, Zhu C, Jumabay M, Yao Z, Wang L, Cai X, Zhang D, Qiao X, Shivkumar K, Pellegrini M, Yao Y, Wu X, Boström KI. PMID: 35896368; PMCID: PMC9585902.
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The derivative of tissue activation as a marker of arrhythmogenic myocardium. Heart Rhythm. 2023 02; 20(2):261-271. Temma T, Lux RL, Yoshie K, Hayase J, Bradfield JS, Shivkumar K, Ajijola OA. PMID: 36270579.
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Autonomic nervous system and arrhythmias in structural heart disease. Auton Neurosci. 2022 12; 243:103037. Sridharan A, Bradfield JS, Shivkumar K, Ajijola OA. PMID: 36201902.
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Towards a Leadless Wirelessly Controlled Intravenous Cardiac Pacemaker. IEEE Trans Biomed Eng. 2022 10; 69(10):3074-3086. Anwar U, Ajijola OA, Shivkumar K, Markovic D. PMID: 35320081.
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Clinical Outcomes in Patients With Dilated Cardiomyopathy and Ventricular Tachycardia. J Am Coll Cardiol. 2022 09 13; 80(11):1045-1056. Zeppenfeld K, Wijnmaalen AP, Ebert M, Baldinger SH, Berruezo A, Catto V, Vaseghi M, Arya A, Kumar S, de Riva M, Deneke T, Gaspar T, Soejima K, van Rein N, Tedrow UB, Piorkowski C, Shivkumar K, Carbucicchio C, Hindricks G, Stevenson WG. PMID: 36075673.
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Sinus Tachycardia: a Multidisciplinary Expert Focused Review. Circ Arrhythm Electrophysiol. 2022 09; 15(9):e007960. Mayuga KA, Fedorowski A, Ricci F, Gopinathannair R, Dukes JW, Gibbons C, Hanna P, Sorajja D, Chung M, Benditt D, Sheldon R, Ayache MB, AbouAssi H, Shivkumar K, Grubb BP, Hamdan MH, Stavrakis S, Singh T, Goldberger JJ, Muldowney JAS, Belham M, Kem DC, Akin C, Bruce BK, Zahka NE, Fu Q, Van Iterson EH, Raj SR, Fouad-Tarazi F, Goldstein DS, Stewart J, Olshansky B. PMID: 36074973; PMCID: PMC9523592.
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Vagally-mediated heart block after myocardial infarction associated with plasticity of epicardial neurons controlling the atrioventricular node. Front Synaptic Neurosci. 2022; 14:960458. Tompkins JD, Buckley U, Salavatian S, Shivkumar K, Ardell JL. PMID: 36147731; PMCID: PMC9488518.
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Detection of inflammation using cardiac positron emission tomography for evaluation of ventricular arrhythmias: An institutional experience. Heart Rhythm. 2022 12; 19(12):2064-2072. Hayase J, Do DH, Liang JJ, Kim M, Lee B, Ajijola O, Buch E, Boyle N, Shivkumar K, Bradfield JS. PMID: 35932988.
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Superior cervical ganglion stimulation results in potent cerebral vasoconstriction in swine. J Vasc Interv Neurol. 2022 Jun; 13(1):35-41. Kim WJ, Samarage HM, Zarrin D, Goel K, Chan C, Qi X, Wang A, Shivkumar K, Ardell J, Colby GP. PMID: 36447624; PMCID: PMC9703949.
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Sympathetic nervous system hyperactivity results in potent cerebral hypoperfusion in swine. Auton Neurosci. 2022 09; 241:102987. Kim WJ, Dacey M, Samarage HM, Zarrin D, Goel K, Chan C, Qi X, Wang AC, Shivkumar K, Ardell J, Colby GP. PMID: 35567916; PMCID: PMC9659432.
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JACC: Clinical Electrophysiology 2021 Young Author Award Winner. JACC Clin Electrophysiol. 2022 04; 8(4):557-558. Shivkumar K. PMID: 35450613.
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JACC: Clinical Electrophysiology 2021 Young Author Award Winner. JACC Clin Electrophysiol. 2022 04; 8(4):559-560. Shivkumar K. PMID: 35450614.
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Electrophysiology and Arrhythmogenesis in the Human Right Ventricular Outflow Tract. Circ Arrhythm Electrophysiol. 2022 03; 15(3):e010630. Aras K, Gams A, Faye NR, Brennan J, Goldrick K, Li J, Zhong Y, Chiang CH, Smith EH, Poston MD, Chivers J, Hanna P, Mori S, Ajijola OA, Shivkumar K, Hoover DB, Viventi J, Rogers JA, Bernus O, Efimov IR. PMID: 35238622; PMCID: PMC9052172.
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Cardiac Sympathectomy and its Enduring Value for the Management of Long QT Syndrome. JACC Clin Electrophysiol. 2022 03; 8(3):295-296. Shivkumar K, Zipes DP. PMID: 35331423.
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Non-invasive Stereotactic Body Radiation Therapy for Refractory Ventricular Arrhythmias: Venturing into the Unknown. J Innov Card Rhythm Manag. 2022 Feb; 13(2):4894-4899. Hayase J, Chin R, Cao M, Hu P, Shivkumar K, Bradfield JS. PMID: 35251759; PMCID: PMC8887931.
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High-resolution structure-function mapping of intact hearts reveals altered sympathetic control of infarct border zones. JCI Insight. 2022 02 08; 7(3). Zhu C, Rajendran PS, Hanna P, Efimov IR, Salama G, Fowlkes CC, Shivkumar K. PMID: 35132963; PMCID: PMC8855798.
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Structural and function organization of intrathoracic extracardiac autonomic projections to the porcine heart: Implications for targeted neuromodulation therapy. Heart Rhythm. 2022 06; 19(6):975-983. Dacey M, Salahudeen O, Swid MA, Carlson C, Shivkumar K, Ardell JL. PMID: 35124232.
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Research Opportunities in Autonomic Neural Mechanisms of Cardiopulmonary Regulation: A Report From the National Heart, Lung, and Blood Institute and the National Institutes of Health Office of the Director Workshop. JACC Basic Transl Sci. 2022 Mar; 7(3):265-293. Mehra R, Tjurmina OA, Ajijola OA, Arora R, Bolser DC, Chapleau MW, Chen PS, Clancy CE, Delisle BP, Gold MR, Goldberger JJ, Goldstein DS, Habecker BA, Handoko ML, Harvey R, Hummel JP, Hund T, Meyer C, Redline S, Ripplinger CM, Simon MA, Somers VK, Stavrakis S, Taylor-Clark T, Undem BJ, Verrier RL, Zucker IH, Sopko G, Shivkumar K. PMID: 35411324; PMCID: PMC8993767.
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Scalable and reversible axonal neuromodulation of the sympathetic chain for cardiac control. Am J Physiol Heart Circ Physiol. 2022 01 01; 322(1):H105-H115. Hadaya J, Buckley U, Gurel NZ, Chan CA, Swid MA, Bhadra N, Vrabec TL, Hoang JD, Smith C, Shivkumar K, Ardell JL. PMID: 34860595; PMCID: PMC8714250.
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Living Anatomy of the Pericardial Space: A Guide for Imaging and Interventions. JACC Clin Electrophysiol. 2021 12; 7(12):1628-1644. Mori S, Bradfield JS, Peacock WJ, Anderson RH, Shivkumar K. PMID: 34949433; PMCID: PMC8712969.
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Surgical ablation after stereotactic body radiation therapy for ventricular arrhythmias. HeartRhythm Case Rep. 2022 Feb; 8(2):73-76. Hayase J, Chin R, Kwon M, Cao M, Hu P, Ajijola O, Boyle N, Shivkumar K, Bradfield JS. PMID: 35242541; PMCID: PMC8858747.
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Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects. Circ Arrhythm Electrophysiol. 2021 11; 14(11):e010181. Delisle BP, George AL, Nerbonne JM, Bass JT, Ripplinger CM, Jain MK, Hermanstyne TO, Young ME, Kannankeril PJ, Duffy JF, Goldhaber JI, Hall MH, Somers VK, Smolensky MH, Garnett CE, Anafi RC, Scheer FAJL, Shivkumar K, Shea SA, Balijepalli RC. PMID: 34719240; PMCID: PMC8815462.
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Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations. Circ Arrhythm Electrophysiol. 2021 11; 14(11):e010190. Delisle BP, George AL, Nerbonne JM, Bass JT, Ripplinger CM, Jain MK, Hermanstyne TO, Young ME, Kannankeril PJ, Duffy JF, Goldhaber JI, Hall MH, Somers VK, Smolensky MH, Garnett CE, Anafi RC, Scheer FAJL, Shivkumar K, Shea SA, Balijepalli RC. PMID: 34719257; PMCID: PMC8865094.
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Mechanism of ventricular premature beats elicited by left stellate ganglion stimulation during acute ischaemia of the anterior left ventricle. Cardiovasc Res. 2021 07 27; 117(9):2083-2091. Boukens BJD, Dacey M, Meijborg VMF, Janse MJ, Hadaya J, Hanna P, Swid MA, Opthof T, Ardell JL, Shivkumar K, Coronel R. PMID: 32853334; PMCID: PMC8318107.
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A single cell transcriptomics map of paracrine networks in the intrinsic cardiac nervous system. iScience. 2021 Jul 23; 24(7):102713. Moss A, Robbins S, Achanta S, Kuttippurathu L, Turick S, Nieves S, Hanna P, Smith EH, Hoover DB, Chen J, Cheng ZJ, Ardell JL, Shivkumar K, Schwaber JS, Vadigepalli R. PMID: 34337356; PMCID: PMC8324809.
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Real three-dimensional cardiac imaging using leading-edge holographic display. Clin Anat. 2021 Sep; 34(6):966-968. Mori S, Shivkumar K. PMID: 34101260; PMCID: PMC8349857.
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Comprehensive Anatomy of the Pericardial Space and the Cardiac Hilum: Anatomical Dissections With Intact Pericardium. JACC Cardiovasc Imaging. 2022 05; 15(5):927-942. Mori S, Hanna P, Dacey MJ, Temma T, Hadaya J, Zhu C, Chang G, Peacock WJ, Fishbein MC, Shivkumar K. PMID: 34147441; PMCID: PMC8655319.
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Neuroscientific therapies for atrial fibrillation. Cardiovasc Res. 2021 06 16; 117(7):1732-1745. Hanna P, Buch E, Stavrakis S, Meyer C, Tompkins JD, Ardell JL, Shivkumar K. PMID: 33989382; PMCID: PMC8208752.
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Visualizing the "internet of the body": Winners of the NIH SPARC Art Contest. Auton Neurosci. 2021 11; 235:102827. Civillico EF, Shivkumar K. PMID: 34119427.
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Clarifying upper airway obstruction-induced ventricular arrhythmic propensity in a model of drug-induced long QT interval and β-adrenergic blockade. Heart Rhythm. 2021 08; 18(8):1392-1393. Mehra R, Shivkumar K. PMID: 33964463.
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JACC: Clinical Electrophysiology 2020 Young Author Award Winner. JACC Clin Electrophysiol. 2021 05; 7(5):690. Shivkumar K. PMID: 34016401.
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JACC: Clinical Electrophysiology 2020 Young Author Award Winner. JACC Clin Electrophysiol. 2021 05; 7(5):691-692. Shivkumar K. PMID: 34016402.
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How to Use Intracardiac Echocardiography to Recognize Normal Cardiac Anatomy. Card Electrophysiol Clin. 2021 06; 13(2):273-283. Khakpour H, Mori S, Bradfield JS, Shivkumar K. PMID: 33990266.
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Stereoscopic three-dimensional anatomy of the heart: another legacy of Dr. Wallace A. McAlpine. Anat Sci Int. 2021 06; 96(3):485-488. Mori S, Shivkumar K. PMID: 33742352.
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Outcomes of Percutaneous Trans-Right Atrial Access to the Left Ventricle for Catheter Ablation of Ventricular Tachycardia in Patients With Mechanical Aortic and Mitral Valves. JAMA Cardiol. 2021 Mar 01; 6(3):326-331. Santangeli P, Hyman MC, Muser D, Callans DJ, Shivkumar K, Marchlinski FE. PMID: 32997112; PMCID: PMC7941197.
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Innervation and Neuronal Control of the Mammalian Sinoatrial Node a Comprehensive Atlas. Circ Res. 2021 04 30; 128(9):1279-1296. Hanna P, Dacey MJ, Brennan J, Moss A, Robbins S, Achanta S, Biscola NP, Swid MA, Rajendran PS, Mori S, Hadaya JE, Smith EH, Peirce SG, Chen J, Havton LA, Cheng ZJ, Vadigepalli R, Schwaber J, Lux RL, Efimov I, Tompkins JD, Hoover DB, Ardell JL, Shivkumar K. PMID: 33629877; PMCID: PMC8284939.
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Cardiac sympathetic denervation and mental health. Auton Neurosci. 2021 05; 232:102787. Khalsa SS, Clausen AN, Shahabi L, Sorg J, Gonzalez SE, Naliboff B, Shivkumar K, Ajijola OA. PMID: 33631539; PMCID: PMC8082676.
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Optical vagus nerve modulation of heart and respiration via heart-injected retrograde AAV. Sci Rep. 2021 02 11; 11(1):3664. Fontaine AK, Futia GL, Rajendran PS, Littich SF, Mizoguchi N, Shivkumar K, Ardell JL, Restrepo D, Caldwell JH, Gibson EA, Weir RFF. PMID: 33574459; PMCID: PMC7878800.
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Catheter ablation of ventricular tachycardia in patients with prior cardiac surgery: An analysis from the International VT Ablation Center Collaborative Group. J Cardiovasc Electrophysiol. 2021 02; 32(2):409-416. Aguilar M, Tedrow UB, Tzou WS, Tung R, Frankel DS, Santangeli P, Vaseghi M, Bunch TJ, Di Biase L, Tholakanahalli VN, Lakkireddy D, Dickfeld T, Weiss JP, Mathuria N, Vergara P, Nakahara S, Bradfield JS, Burkhardt JD, Stevenson WG, Callans DJ, Della Bella P, Natale A, Shivkumar K, Marchlinski FE, Sauer WH. PMID: 33355965.
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Arrhythmic Risk Profile and Outcomes of Patients Undergoing Cardiac Sympathetic Denervation for Recurrent Monomorphic Ventricular Tachycardia After Ablation. J Am Heart Assoc. 2021 01 19; 10(2):e018371. Dusi V, Gornbein J, Do DH, Sorg JM, Khakpour H, Krokhaleva Y, Ajijola OA, Macias C, Bradfield JS, Buch E, Fujimura OA, Boyle NG, Yanagawa J, Lee JM, Shivkumar K, Vaseghi M. PMID: 33441022; PMCID: PMC7955320.
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Atrial tachycardia arising from the distal left atrial appendage requiring high-power endocardial and epicardial ablation. HeartRhythm Case Rep. 2021 Mar; 7(3):157-161. Khakpour H, Hayase JH, Bradfield JS, Buch E, Shivkumar K. PMID: 33786311; PMCID: PMC7987893.
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Masked premature ventricular contractions and intradevice interaction causing ventricular fibrillation. HeartRhythm Case Rep. 2021 Feb; 7(2):69-73. Do DH, Meyer S, Bradfield J, Shivkumar K, Boyle NG, Khakpour H. PMID: 33665104; PMCID: PMC7897743.
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Arrhythmia exacerbation after post-infarction ventricular tachycardia ablation: prevalence and prognostic significance. Europace. 2020 11 01; 22(11):1680-1687. Siontis KC, Kim HM, Vergara P, Peretto G, Do DH, de Riva M, Lam A, Qian P, Yokokawa M, Jongnarangsin K, Latchamsetty R, Jais P, Sacher F, Tedrow U, Shivkumar K, Zeppenfeld K, Della Bella P, Stevenson WG, Morady F, Bogun FM. PMID: 32830247.
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Rapid measurement of cardiac neuropeptide dynamics by capacitive immunoprobe in the porcine heart. Am J Physiol Heart Circ Physiol. 2021 01 01; 320(1):H66-H76. Kluge N, Dacey M, Hadaya J, Shivkumar K, Chan SA, Ardell JL, Smith C. PMID: 33095651; PMCID: PMC7847069.
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Role of angiotensin-converting enzyme 2 and pericytes in cardiac complications of COVID-19 infection. Am J Physiol Heart Circ Physiol. 2020 11 01; 319(5):H1059-H1068. Robinson FA, Mihealsick RP, Wagener BM, Hanna P, Poston MD, Efimov IR, Shivkumar K, Hoover DB. PMID: 33036546; PMCID: PMC7789968.
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Catheter Ablation of Ventricular Tachycardia: First, Treat the Underlying Disease. J Am Coll Cardiol. 2020 10 06; 76(14):1657-1659. Shivkumar K, Do DH. PMID: 33004130.
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The U.S. National Institutes of Health and the Universal Language of Humanitarianism. JACC Clin Electrophysiol. 2020 10; 6(10):1219-1220. Shivkumar K. PMID: 33092746.
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Genotype Predicts Outcomes in Fetuses and Neonates With Severe Congenital Long QT Syndrome. JACC Clin Electrophysiol. 2020 11; 6(12):1561-1570. Moore JP, Gallotti RG, Shannon KM, Bos JM, Sadeghi E, Strasburger JF, Wakai RT, Horigome H, Clur SA, Hill AC, Shah MJ, Behere S, Sarquella-Brugada G, Czosek R, Etheridge SP, Fischbach P, Kannankeril PJ, Motonaga K, Landstrom AP, Williams M, Patel A, Dagradi F, Tan RB, Stephenson E, Krishna MR, Miyake CY, Lee ME, Sanatani S, Balaji S, Young ML, Siddiqui S, Schwartz PJ, Shivkumar K, Ackerman MJ. PMID: 33213816; PMCID: PMC7679474.
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Non-invasive stereotactic body radiation therapy for refractory ventricular arrhythmias: an institutional experience. J Interv Card Electrophysiol. 2021 Sep; 61(3):535-543. Chin R, Hayase J, Hu P, Cao M, Deng J, Ajijola O, Do D, Vaseghi M, Buch E, Khakpour H, Fujimura O, Krokhaleva Y, Macias C, Sorg J, Gima J, Pavez G, Boyle NG, Steinberg M, Shivkumar K, Bradfield JS. PMID: 32803639.
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Targeting the β-adrenergic receptor in the clinical management of congenital long QT syndrome. Ann N Y Acad Sci. 2020 08; 1474(1):27-46. Saadeh K, Shivkumar K, Jeevaratnam K. PMID: 32901453.
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Journal of the American College of Cardiology: Clinical Electrophysiology: The Next Phase of the Voyage. JACC Clin Electrophysiol. 2020 07; 6(7):753-755. Shivkumar K. PMID: 32703554.
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Anatomy of the Pericardial Space. Card Electrophysiol Clin. 2020 09; 12(3):265-270. Hayase J, Mori S, Shivkumar K, Bradfield JS. PMID: 32771181.
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Epicardial Interventions in Electrophysiology: Transformation to an Established Approach. Card Electrophysiol Clin. 2020 09; 12(3):xv. Bradfield JS, Shivkumar K. PMID: 32771197.
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Recurrent ventricular tachycardia after cardiac sympathetic denervation: Prolonged cycle length with improved hemodynamic tolerance and ablation outcomes. J Cardiovasc Electrophysiol. 2020 09; 31(9):2382-2392. Hayase J, Dusi V, Do D, Ajijola OA, Vaseghi M, Lee JM, Yanagawa J, Hoftman N, Revels S, Buch EF, Khakpour H, Fujimura O, Krokhaleva Y, Macias C, Sorg J, Gima J, Pavez G, Boyle NG, Shivkumar K, Bradfield JS. PMID: 32558054; PMCID: PMC7719072.
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The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade. Eur Heart J. 2020 06 14; 41(23):2168-2179. Kalla M, Hao G, Tapoulal N, Tomek J, Liu K, Woodward L, ‘Oxford Acute Myocardial Infarction (OxAMI) Study’, Dall'Armellina E, Banning AP, Choudhury RP, Neubauer S, Kharbanda RK, Channon KM, Ajijola OA, Shivkumar K, Paterson DJ, Herring N. PMID: 31834357; PMCID: PMC7299634.
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Ebstein's anomaly: Structural insights for the interventional electrophysiologist. Heart Rhythm. 2020 07; 17(7):1099-1100. Moore JP, Shivkumar K. PMID: 32380287.
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Electrocardiographic right ventricular strain precedes hypoxic pulseless electrical activity cardiac arrests: Looking beyond pulmonary embolism. Resuscitation. 2020 06; 151:127-134. Do DH, Yang JJ, Kuo A, Bradfield JS, Hu X, Shivkumar K, Boyle NG. PMID: 32360319; PMCID: PMC7307602.
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Cardiovascular autonomic reflex function after bilateral cardiac sympathetic denervation for ventricular arrhythmias. Heart Rhythm. 2020 08; 17(8):1320-1327. Dusi V, Shahabi L, Lapidus RC, Sorg JM, Naliboff BD, Shivkumar K, Khalsa SS, Ajijola OA. PMID: 32325196; PMCID: PMC7395890.
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Avoiding the 'cart before the horse': the importance of continued basic and translational studies of renal denervation. Europace. 2020 04 01; 22(4):513-514. Bradfield JS, Shivkumar K. PMID: 32249912.
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Fast in vivo detection of myocardial norepinephrine levels in the beating porcine heart. Am J Physiol Heart Circ Physiol. 2020 05 01; 318(5):H1091-H1099. Chan SA, Vaseghi M, Kluge N, Shivkumar K, Ardell JL, Smith C. PMID: 32216617; PMCID: PMC7346543.
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Coronary Sinus Neuropeptide Y Levels and Adverse Outcomes in Patients With Stable Chronic Heart Failure. JAMA Cardiol. 2020 03 01; 5(3):318-325. Ajijola OA, Chatterjee NA, Gonzales MJ, Gornbein J, Liu K, Li D, Paterson DJ, Shivkumar K, Singh JP, Herring N. PMID: 31876927; PMCID: PMC6990798.
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Giovanni Maria Lancisi's description of commotio cordis. Heart Rhythm. 2020 04; 17(4):674-675. Shivkumar K, Boyle NG. PMID: 31981737.
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Three-dimensional imaging of the pericardial space. HeartRhythm Case Rep. 2020 Apr; 6(4):194-197. Mori S, Shivkumar K. PMID: 32322495; PMCID: PMC7156978.
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Stellate ganglion stimulation causes spatiotemporal changes in ventricular repolarization in pig. Heart Rhythm. 2020 05; 17(5 Pt A):795-803. Meijborg VMF, Boukens BJD, Janse MJ, Salavatian S, Dacey MJ, Yoshie K, Opthof T, Swid MA, Hoang JD, Hanna P, Ardell J, Shivkumar K, Coronel R. PMID: 31917369; PMCID: PMC7196037.
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Prognostic impact of atrial rhythm and dimension in patients with structural heart disease undergoing cardiac sympathetic denervation for ventricular arrhythmias. Heart Rhythm. 2020 05; 17(5 Pt A):714-720. Dusi V, Sorg JM, Gornbein J, Gima J, Yanagawa J, Lee JM, Vecerek N, Vaseghi M, Bradfield JS, De Ferrari GM, Shivkumar K, Ajijola OA. PMID: 31837474; PMCID: PMC7196021.
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Cardiac sympathectomy and spinal cord stimulation attenuate reflex-mediated norepinephrine release during ischemia preventing ventricular fibrillation. JCI Insight. 2019 12 05; 4(23). Ardell JL, Foreman RD, Armour JA, Shivkumar K. PMID: 31671074; PMCID: PMC6962015.
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A Novel Risk Stratification Score for Sudden Cardiac Death Prediction in Middle-Aged, Nonischemic Dilated Cardiomyopathy Patients: The ESTIMATED Score. Can J Cardiol. 2020 07; 36(7):1121-1129. Li X, Fan X, Li S, Sun W, Shivkumar K, Zhao S, Lu M, Yao Y. PMID: 32249067.
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Renal denervation as adjunctive therapy to cardiac sympathetic denervation for ablation refractory ventricular tachycardia. Heart Rhythm. 2020 02; 17(2):220-227. Bradfield JS, Hayase J, Liu K, Moriarty J, Kee ST, Do D, Ajijola OA, Vaseghi M, Gima J, Sorg J, Cote S, Pavez G, Buch E, Khakpour H, Krokhaleva Y, Macias C, Fujimura O, Boyle NG, Shivkumar K. PMID: 31539629.
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Structural Interventions and Potential Unforeseen Limits on Access to Ventricular Tachycardia Substrates. JACC Clin Electrophysiol. 2019 08; 5(8):996-997. Diamantakos E, Harvey R, Shivkumar K, Bradfield JS. PMID: 31439305.
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Neuromodulation for Ventricular Tachycardia and Atrial Fibrillation: A Clinical Scenario-Based Review. JACC Clin Electrophysiol. 2019 08; 5(8):881-896. Zhu C, Hanna P, Rajendran PS, Shivkumar K. PMID: 31439288; PMCID: PMC6773263.
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Publisher Correction: Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nat Protoc. 2019 Aug; 14(8):2597. Challis RC, Kumar SR, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. PMID: 31312046.
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Cardiac perforation complicating cardiac electrophysiology procedures: value of angiography and use of a closure device to avoid cardiac surgery. J Interv Card Electrophysiol. 2020 Aug; 58(2):193-201. Shenthar J, Singh B, Banavalikar B, Chakali SS, Delhaas T, Shivkumar K, Bradfield JS. PMID: 31250253.
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Cardiac sympathetic denervation for refractory ventricular arrhythmias in patients with structural heart disease: A systematic review. Heart Rhythm. 2019 10; 16(10):1499-1505. Shah R, Assis F, Alugubelli N, Okada DR, Cardoso R, Shivkumar K, Tandri H. PMID: 31252084.
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Increased baseline ECG R-R dispersion predicts improvement in systolic function after atrial fibrillation ablation. Open Heart. 2019; 6(1):e000958. Koene RJ, Buch E, Seo YJ, Li JM, Mbai M, Chandrashekhar Y, Shivkumar K, Tholakanahalli VN. PMID: 31328002; PMCID: PMC6609144.
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Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation. Sci Transl Med. 2019 05 22; 11(493). Scherschel K, Hedenus K, Jungen C, Lemoine MD, Rübsamen N, Veldkamp MW, Klatt N, Lindner D, Westermann D, Casini S, Kuklik P, Eickholt C, Klöcker N, Shivkumar K, Christ T, Zeller T, Willems S, Meyer C. PMID: 31118294.
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Anesthetizing the Fibrillating Heart. J Am Heart Assoc. 2019 05 21; 8(10):e012713. Hanna P, Zhu C, Rajendran PS, Shivkumar K. PMID: 31068060; PMCID: PMC6585315.
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Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies. Nat Commun. 2019 04 26; 10(1):1944. Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, Shivkumar K. PMID: 31028266; PMCID: PMC6486614.
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Catheter Ablation of Ventricular Arrhythmias. N Engl J Med. 2019 04 18; 380(16):1555-1564. Shivkumar K. PMID: 30995375.
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Premature ventricular contraction diurnal profiles predict distinct clinical characteristics and beta-blocker responses. J Cardiovasc Electrophysiol. 2019 06; 30(6):836-843. Hamon D, Swid MA, Rajendran PS, Liu A, Boyle NG, Shivkumar K, Bradfield JS. PMID: 30964570.
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Neuroinflammation as a mechanism for cardiovascular diseases. Int J Cardiol. 2019 08 01; 288:128-129. Rajendran PS, Hanna P, Zhu C, Shivkumar K. PMID: 30979606; PMCID: PMC7155386.
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Autonomic Nervous System Dysfunction: JACC Focus Seminar. J Am Coll Cardiol. 2019 03 19; 73(10):1189-1206. Goldberger JJ, Arora R, Buckley U, Shivkumar K. PMID: 30871703; PMCID: PMC6958998.
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Feasibility of percutaneous epicardial mapping and ablation for refractory atrial fibrillation: Insights into substrate and lesion transmurality. Heart Rhythm. 2019 08; 16(8):1151-1159. Jiang R, Buch E, Gima J, Upadhyay GA, Nayak HM, Beaser AD, Aziz Z, Shivkumar K, Tung R. PMID: 30776449.
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Reply to the Editor- Bipolar ablation of refractory VT circuits: Current opportunities and limitations. HeartRhythm Case Rep. 2019 May; 5(5):288-289. Al-Hadithi ABAK, Khakpour H, Cruz D, Boyle NG, Shivkumar K, Bradfield JS. PMID: 31193245; PMCID: PMC6522634.
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Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nat Protoc. 2019 02; 14(2):379-414. Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. PMID: 30626963.
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Catheter ablation in the vicinity of the proximal conduction system: Your eyes cannot see what your mind does not know. Heart Rhythm. 2019 03; 16(3):378-379. Bradfield JS, Fujimura O, Boyle NG, Shivkumar K. PMID: 30630100.
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Journal of Cardiovascular Electrophysiology: Redefining Our Mission. J Cardiovasc Electrophysiol. 2019 01; 30(1):5-6. Ellenbogen KA, Tung R, Shivkumar K, Miller JM. PMID: 30556193.
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Neural ablation to treat ventricular arrhythmias. Europace. 2018 12 01; 20(12):1880-1881. Hanna P, Rajendran PS, Shivkumar K. PMID: 29931207; PMCID: PMC6275468.
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Predictive Score for Identifying Survival and Recurrence Risk Profiles in Patients Undergoing Ventricular Tachycardia Ablation: The I-VT Score. Circ Arrhythm Electrophysiol. 2018 12; 11(12):e006730. Vergara P, Tzou WS, Tung R, Brombin C, Nonis A, Vaseghi M, Frankel DS, Di Biase L, Tedrow U, Mathuria N, Nakahara S, Tholakanahalli V, Bunch TJ, Weiss JP, Dickfeld T, Lakireddy D, Burkhardt JD, Santangeli P, Callans D, Natale A, Marchlinski F, Stevenson WG, Shivkumar K, Sauer WH, Della Bella P. PMID: 30562104; PMCID: PMC6301075.
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Contemporary Management of Electrical Storm. Heart Lung Circ. 2019 Jan; 28(1):123-133. Geraghty L, Santangeli P, Tedrow UB, Shivkumar K, Kumar S. PMID: 30554598.
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Ageing, the autonomic nervous system and arrhythmia: From brain to heart. Ageing Res Rev. 2018 Dec; 48:40-50. Chadda KR, Ajijola OA, Vaseghi M, Shivkumar K, Huang CL, Jeevaratnam K. PMID: 30300712.
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Incessant intraseptal ventricular tachycardia ablated utilizing extracorporeal membrane oxygenation and bipolar ablation. HeartRhythm Case Rep. 2018 Dec; 4(12):557-560. Al-Hadithi ABAK, Khakpour H, Cruz D, Boyle NG, Shivkumar K, Bradfield JS. PMID: 30581730; PMCID: PMC6301887.
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Targeting the Cardiac Ganglionated Plexi for Atrial Fibrillation: Modulate or Destroy? JACC Clin Electrophysiol. 2018 10; 4(10):1359-1361. Hanna P, Shivkumar K. PMID: 30336882; PMCID: PMC7098458.
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Persistent left superior vena cava as an arrhythmogenic source in atrial fibrillation: results from a multicenter experience. J Interv Card Electrophysiol. 2019 Mar; 54(2):93-100. Turagam MK, Atoui M, Atkins D, Di Biase L, Shivkumar K, Jared Bunch T, Mohanty S, Gianni C, Natale A, Lakkireddy D. PMID: 30259306.
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Progression of myocardial ischemia leads to unique changes in immediate-early gene expression in the spinal cord dorsal horn. Am J Physiol Heart Circ Physiol. 2018 12 01; 315(6):H1592-H1601. Saddic LA, Howard-Quijano K, Kipke J, Kubo Y, Dale EA, Hoover D, Shivkumar K, Eghbali M, Mahajan A. PMID: 30216122; PMCID: PMC6336975.
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Microstructural Infarct Border Zone Remodeling in the Post-infarct Swine Heart Measured by Diffusion Tensor MRI. Front Physiol. 2018; 9:826. Kung GL, Vaseghi M, Gahm JK, Shevtsov J, Garfinkel A, Shivkumar K, Ennis DB. PMID: 30246802; PMCID: PMC6113632.
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Percutaneous Hemodynamic Assist Devices: Unloading the Left Atrium to Prevent Atrial Remodeling. J Am Coll Cardiol. 2018 08 14; 72(7):751-753. Shivkumar K, Hanna P. PMID: 30092951.
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Calming the Nervous Heart: Autonomic Therapies in Heart Failure. Card Fail Rev. 2018 Aug; 4(2):92-98. Hanna P, Shivkumar K, Ardell JL. PMID: 30206483; PMCID: PMC6125704.
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Outcomes of Catheter Ablation of Ventricular Tachycardia Based on Etiology in Nonischemic Heart Disease: An International Ventricular Tachycardia Ablation Center Collaborative Study. JACC Clin Electrophysiol. 2018 09; 4(9):1141-1150. Vaseghi M, Hu TY, Tung R, Vergara P, Frankel DS, Di Biase L, Tedrow UB, Gornbein JA, Yu R, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Burkhardt JD, Tholakanahalli VN, Dickfeld TM, Weiss JP, Bunch TJ, Reddy M, Callans DJ, Lakkireddy DR, Natale A, Marchlinski FE, Stevenson WG, Della Bella P, Shivkumar K. PMID: 30236386; PMCID: PMC6242273.
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Catheter Ablation of Ventricular Arrhythmia for Ebstein's Anomaly in Unoperated and Post-Surgical Patients. JACC Clin Electrophysiol. 2018 10; 4(10):1300-1307. Moore JP, Shannon KM, Gallotti RG, McLeod CJ, Chiriac A, Walsh EP, Sreeram N, Patel AR, De Groot NM, von Alvensleben J, Balaji S, Frankel DS, Miyake CY, Perry JC, Shivkumar K. PMID: 30336876.
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Intramyocardial radiofrequency ablation of ventricular arrhythmias using intracoronary wire mapping and a coronary reentry system: Description of a novel technique. HeartRhythm Case Rep. 2018 Jul; 4(7):285-292. Romero J, Diaz JC, Hayase J, Dave RH, Bradfield JS, Shivkumar K. PMID: 30023273; PMCID: PMC6050428.
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RNA Sequencing Reveals Novel Transcripts from Sympathetic Stellate Ganglia During Cardiac Sympathetic Hyperactivity. Sci Rep. 2018 06 05; 8(1):8633. Bardsley EN, Davis H, Ajijola OA, Buckler KJ, Ardell JL, Shivkumar K, Paterson DJ. PMID: 29872217; PMCID: PMC5988725.
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Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity. JCI Insight. 2018 05 03; 3(9). Liu K, Li D, Hao G, McCaffary D, Neely O, Woodward L, Ioannides D, Lu CJ, Brescia M, Zaccolo M, Tandri H, Ajijola OA, Ardell JL, Shivkumar K, Paterson DJ. PMID: 29720569; PMCID: PMC6012514.
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Endocardial ablation of ventricular ectopic beats arising from the basal inferoseptal process of the left ventricle. Heart Rhythm. 2018 09; 15(9):1356-1362. Li A, Zuberi Z, Bradfield JS, Zarif JK, Ward DE, Anderson RH, Shivkumar K, Saba MM. PMID: 29709577.
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Limitations of 12-lead electrocardiogram wide complex tachycardia algorithms in a patient with left atrial flutter and large myocardial infarction. HeartRhythm Case Rep. 2019 Feb; 5(2):70-73. Macias C, Khakpour H, Buch E, Shivkumar K, Bradfield JS. PMID: 30820399; PMCID: PMC6379568.
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Ventricular arrhythmia burden after transcatheter versus surgical pulmonary valve replacement. Heart. 2018 11; 104(21):1791-1796. Wadia SK, Lluri G, Aboulhosn JA, Shivkumar K, Reemtsen BL, Laks H, Biniwale RM, Levi DS, Salem M, Moore JP. PMID: 29636402.
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Autonomic Regulation and Ventricular Arrhythmias. Curr Treat Options Cardiovasc Med. 2018 Apr 07; 20(5):38. Meng L, Shivkumar K, Ajijola O. PMID: 29627871.
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Morphological Spectra of Adult Human Stellate Ganglia: Implications for Thoracic Sympathetic Denervation. Anat Rec (Hoboken). 2018 Jul; 301(7):1244-1250. Kwon OJ, Pendekanti S, Fox JN, Yanagawa J, Fishbein MC, Shivkumar K, Lambert HW, Ajijola OA. PMID: 29451372; PMCID: PMC7105504.
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Ablation of Intracavitary Structures: Anatomy, Anatomy, Anatomy. J Innov Card Rhythm Manag. 2018 Feb; 9(2):3014-3015. Bradfield JS, Shivkumar K. PMID: 32494484; PMCID: PMC7252887.
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Mechanisms and management of refractory ventricular arrhythmias in the age of autonomic modulation. Heart Rhythm. 2018 08; 15(8):1252-1260. Bradfield JS, Ajijola OA, Vaseghi M, Shivkumar K. PMID: 29454137.
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Cardiac vanilloid receptor-1 afferent depletion enhances stellate ganglion neuronal activity and efferent sympathetic response to cardiac stress. Am J Physiol Heart Circ Physiol. 2018 05 01; 314(5):H954-H966. Yoshie K, Rajendran PS, Massoud L, Kwon O, Tadimeti V, Salavatian S, Ardell JL, Shivkumar K, Ajijola OA. PMID: 29351450; PMCID: PMC6008140.
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Programmable Hypertension Control: Another Possible Indication for Implanted Pacemakers. J Am Heart Assoc. 2017 12 23; 6(12). Do DH, Shivkumar K. PMID: 29275376; PMCID: PMC5779065.
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Ventricular Tachycardia Ablation in the Elderly: An International Ventricular Tachycardia Center Collaborative Group Analysis. Circ Arrhythm Electrophysiol. 2017 Dec; 10(12). Vakil K, Garcia S, Tung R, Vaseghi M, Tedrow U, Della Bella P, Frankel DS, Vergara P, Di Biase L, Nagashima K, Nakahara S, Tzou WS, Burkhardt JD, Dickfeld T, Weiss JP, Bunch J, Callans D, Lakkireddy D, Natale A, Sauer WH, Stevenson WG, Marchlinski F, Shivkumar K, Tholakanahalli VN. PMID: 29254946.
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Right ventricular lead proarrhythmia: A novel intervention for an under-recognized phenomenon. HeartRhythm Case Rep. 2018 Feb; 4(2):50-53. Hayase J, Khakpour H, Shivkumar K, Bradfield JS. PMID: 29876287; PMCID: PMC5988465.
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Hemodynamic Support in Ventricular Tachycardia Ablation: An International VT Ablation Center Collaborative Group Study. JACC Clin Electrophysiol. 2017 12 26; 3(13):1534-1543. Turagam MK, Vuddanda V, Atkins D, Santangeli P, Frankel DS, Tung R, Vaseghi M, Sauer WH, Tzou W, Mathuria N, Nakahara S, Dickfeld TM, Bunch TJ, Weiss P, Di Biase L, Tholakanahalli V, Vakil K, Tedrow UB, Stevenson WG, Della Bella P, Shivkumar K, Marchlinski FE, Callans DJ, Natale A, Reddy M, Lakkireddy D. PMID: 29759835.
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Hybrid surgical vs percutaneous access epicardial ventricular tachycardia ablation. Heart Rhythm. 2018 04; 15(4):512-519. Li A, Hayase J, Do D, Buch E, Vaseghi M, Ajijola OA, Macias C, Krokhaleva Y, Khakpour H, Boyle NG, Benharash P, Biniwale R, Shivkumar K, Bradfield JS. PMID: 29132931.
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Post-Extrasystolic Potentiation as a Predictor of Recovery of Left Ventricular Dysfunction After Radiofrequency Catheter Ablation. JACC Clin Electrophysiol. 2017 11; 3(11):1283-1291. Krishnan B, Sankar A, Anand I, Adabag S, Li JM, McFalls EO, Benditt DG, Shivkumar K, Tholakanahalli VN. PMID: 29759625.
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Cardiac magnetic resonance imaging using wideband sequences in patients with nonconditional cardiac implanted electronic devices. Heart Rhythm. 2018 02; 15(2):218-225. Do DH, Eyvazian V, Bayoneta AJ, Hu P, Finn JP, Bradfield JS, Shivkumar K, Boyle NG. PMID: 29017930; PMCID: PMC5823604.
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Inflammation, oxidative stress, and glial cell activation characterize stellate ganglia from humans with electrical storm. JCI Insight. 2017 09 21; 2(18). Ajijola OA, Hoover DB, Simerly TM, Brown TC, Yanagawa J, Biniwale RM, Lee JM, Sadeghi A, Khanlou N, Ardell JL, Shivkumar K. PMID: 28931760; PMCID: PMC5621921.
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Vagal Neuromodulation for Atrial Arrhythmias. JACC Clin Electrophysiol. 2017 09; 3(9):939-941. Shivkumar K, Ardell JL. PMID: 29759718.
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Incidence and significance of adhesions encountered during epicardial mapping and ablation of ventricular tachycardia in patients with no history of prior cardiac surgery or pericarditis. Heart Rhythm. 2018 01; 15(1):65-74. Li A, Buch E, Boyle NG, Shivkumar K, Bradfield JS. PMID: 28917555.
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Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review. JACC Clin Electrophysiol. 2017 09; 3(9):942-949. Meng L, Tseng CH, Shivkumar K, Ajijola O. PMID: 29270467; PMCID: PMC5734652.
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Successful ventricular tachycardia ablation in patients with electrical storm reduces recurrences and improves survival. Heart Rhythm. 2018 01; 15(1):48-55. Vergara P, Tung R, Vaseghi M, Brombin C, Frankel DS, Di Biase L, Nagashima K, Tedrow U, Tzou WS, Sauer WH, Mathuria N, Nakahara S, Vakil K, Tholakanahalli V, Bunch TJ, Weiss JP, Dickfeld T, Vunnam R, Lakireddy D, Burkhardt JD, Correra A, Santangeli P, Callans D, Natale A, Marchlinski F, Stevenson WG, Shivkumar K, Della Bella P. PMID: 28843418.
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Parasympathetic dysfunction and antiarrhythmic effect of vagal nerve stimulation following myocardial infarction. JCI Insight. 2017 Aug 17; 2(16). Vaseghi M, Salavatian S, Rajendran PS, Yagishita D, Woodward WR, Hamon D, Yamakawa K, Irie T, Habecker BA, Shivkumar K. PMID: 28814663; PMCID: PMC5621871.
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Coronary sinus ostium in the lateral right atrium: Implications for the electrophysiologist. HeartRhythm Case Rep. 2017 Oct; 3(10):487-489. Mathuria N, Bachani N, Mandapati R, Shivkumar K, Lokhandwala Y. PMID: 29062704; PMCID: PMC5643862.
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Circadian variability patterns predict and guide premature ventricular contraction ablation procedural inducibility and outcomes. Heart Rhythm. 2018 01; 15(1):99-106. Hamon D, Abehsira G, Gu K, Liu A, Blaye-Felice Sadron M, Billet S, Kambur T, Swid MA, Boyle NG, Dandamudi G, Maury P, Chen M, Miller JM, Lellouche N, Shivkumar K, Bradfield JS. PMID: 28765087.
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Cardiac neuroanatomy - Imaging nerves to define functional control. Auton Neurosci. 2017 Nov; 207:48-58. Hanna P, Rajendran PS, Ajijola OA, Vaseghi M, Andrew Armour J, Ardell JL, Shivkumar K. PMID: 28802636; PMCID: PMC5680093.
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Recurrent myocardial infarction: Mechanisms of free-floating adaptation and autonomic derangement in networked cardiac neural control. PLoS One. 2017; 12(7):e0180194. Kember G, Ardell JL, Shivkumar K, Armour JA. PMID: 28692680; PMCID: PMC5503241.
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Cardiac Sympathetic Denervation for Refractory Ventricular Arrhythmias. J Am Coll Cardiol. 2017 Jun 27; 69(25):3070-3080. Vaseghi M, Barwad P, Malavassi Corrales FJ, Tandri H, Mathuria N, Shah R, Sorg JM, Gima J, Mandal K, Sàenz Morales LC, Lokhandwala Y, Shivkumar K. PMID: 28641796; PMCID: PMC6330109.
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Cardiac inflammation and ventricular tachycardia in Chagas disease. HeartRhythm Case Rep. 2017 Aug; 3(8):392-395. Shapiro H, Meymandi S, Shivkumar K, Bradfield JS. PMID: 28840107; PMCID: PMC5558168.
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Brugada syndrome-Malignant phenotype associated with acute cardiac inflammation? HeartRhythm Case Rep. 2017 Aug; 3(8):384-388. Li A, Tung R, Shivkumar K, Bradfield JS. PMID: 28840105; PMCID: PMC5558165.
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Bioelectronic block of paravertebral sympathetic nerves mitigates post-myocardial infarction ventricular arrhythmias. Heart Rhythm. 2017 11; 14(11):1665-1672. Chui RW, Buckley U, Rajendran PS, Vrabec T, Shivkumar K, Ardell JL. PMID: 28629852.
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Spinal cord stimulation reduces ventricular arrhythmias during acute ischemia by attenuation of regional myocardial excitability. Am J Physiol Heart Circ Physiol. 2017 Aug 01; 313(2):H421-H431. Howard-Quijano K, Takamiya T, Dale EA, Kipke J, Kubo Y, Grogan T, Afyouni A, Shivkumar K, Mahajan A. PMID: 28576833; PMCID: PMC5582923.
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Cardiac Arrhythmias in Adults with Congenital Heart Disease. Card Electrophysiol Clin. 2017 06; 9(2):xv-xvi. Balaji S, Mandapati R, Shivkumar K. PMID: 28457248.
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Characterization of Aortic Valve Closure Artifact During Outflow Tract Mapping: Correlation With Hemodynamics and Mechanical Valves. Circ Arrhythm Electrophysiol. 2017 Jun; 10(6). Romero J, Ajijola O, Shivkumar K, Tung R. PMID: 28630170.
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Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction. PLoS One. 2017; 12(5):e0177750. Gao C, Howard-Quijano K, Rau C, Takamiya T, Song Y, Shivkumar K, Wang Y, Mahajan A. PMID: 28542617; PMCID: PMC5436752.
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Outcomes after repeat ablation of ventricular tachycardia in structural heart disease: An analysis from the International VT Ablation Center Collaborative Group. Heart Rhythm. 2017 07; 14(7):991-997. Tzou WS, Tung R, Frankel DS, Di Biase L, Santangeli P, Vaseghi M, Bunch TJ, Weiss JP, Tholakanahalli VN, Lakkireddy D, Vunnam R, Dickfeld T, Mathuria N, Tedrow U, Vergara P, Vakil K, Nakahara S, Burkhardt JD, Stevenson WG, Callans DJ, Della Bella P, Natale A, Shivkumar K, Marchlinski FE, Sauer WH. PMID: 28506710.
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Early Mortality After Catheter Ablation of Ventricular Tachycardia in Patients With Structural Heart Disease. J Am Coll Cardiol. 2017 May 02; 69(17):2105-2115. Santangeli P, Frankel DS, Tung R, Vaseghi M, Sauer WH, Tzou WS, Mathuria N, Nakahara S, Dickfeldt TM, Lakkireddy D, Bunch TJ, Di Biase L, Natale A, Tholakanahalli V, Tedrow UB, Kumar S, Stevenson WG, Della Bella P, Shivkumar K, Marchlinski FE, Callans DJ, International VT Ablation Center Collaborative Group. PMID: 28449770.
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Could less be more in catheter ablation for persistent atrial fibrillation? Pulmonary vein isolation reconsidered. Heart Rhythm. 2017 05; 14(5):668-669. Buch E, Shivkumar K. PMID: 28434447.
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Sympathetic neural recording-It is all in the details. Heart Rhythm. 2017 07; 14(7):972-973. Ardell JL, Shivkumar K. PMID: 28438720.
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Pattern Breaks on the Surface ECG: Can We Anticipate a Long Day Ahead? J Cardiovasc Electrophysiol. 2017 05; 28(5):515-516. Bradfield JS, Shivkumar K. PMID: 28257570.
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Permanent His-bundle pacing for cardiac resynchronization therapy: Initial feasibility study in lieu of left ventricular lead. Heart Rhythm. 2017 09; 14(9):1353-1361. Ajijola OA, Upadhyay GA, Macias C, Shivkumar K, Tung R. PMID: 28400315.
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Premature Ventricular Contraction Coupling Interval Variability Destabilizes Cardiac Neuronal and Electrophysiological Control: Insights From Simultaneous Cardioneural Mapping. Circ Arrhythm Electrophysiol. 2017 Apr; 10(4). Hamon D, Rajendran PS, Chui RW, Ajijola OA, Irie T, Talebi R, Salavatian S, Vaseghi M, Bradfield JS, Armour JA, Ardell JL, Shivkumar K. PMID: 28408652; PMCID: PMC5407491.
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Electrophysiology of Hypokalemia and Hyperkalemia. Circ Arrhythm Electrophysiol. 2017 03; 10(3). Weiss JN, Qu Z, Shivkumar K. PMID: 28314851; PMCID: PMC5399982.
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Temporal Trends and Temperature-Related Incidence of Electrical Storm: The TEMPEST Study (Temperature-Related Incidence of Electrical Storm). Circ Arrhythm Electrophysiol. 2017 Mar; 10(3). Guerra F, Bonelli P, Flori M, Cipolletta L, Carbucicchio C, Izquierdo M, Kozluk E, Shivkumar K, Vaseghi M, Patani F, Cupido C, Pala S, Ruiz-Granell R, Ferrero A, Tondo C, Capucci A. PMID: 28314850.
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Value of a Posterior Electrocardiographic Lead for Localization of Ventricular Outflow Tract Arrhythmias: The V4/V8 Ratio. JACC Clin Electrophysiol. 2017 07; 3(7):678-686. Zhang F, Hamon D, Fang Z, Xu Y, Yang B, Ju W, Bradfield J, Shivkumar K, Chen M, Tung R. PMID: 29759536.
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Bioelectronic neuromodulation of the paravertebral cardiac efferent sympathetic outflow and its effect on ventricular electrical indices. Heart Rhythm. 2017 07; 14(7):1063-1070. Buckley U, Chui RW, Rajendran PS, Vrabec T, Shivkumar K, Ardell JL. PMID: 28219848; PMCID: PMC5478457.
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Sympathetic modulation of electrical activation in normal and infarcted myocardium: implications for arrhythmogenesis. Am J Physiol Heart Circ Physiol. 2017 Mar 01; 312(3):H608-H621. Ajijola OA, Lux RL, Khahera A, Kwon O, Aliotta E, Ennis DB, Fishbein MC, Ardell JL, Shivkumar K. PMID: 28087519; PMCID: PMC5402014.
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Ganglionated plexus ablation for atrial fibrillation: Just because we can, does that mean we should? Heart Rhythm. 2017 01; 14(1):133-134. Buckley U, Rajendran PS, Shivkumar K. PMID: 28007095; PMCID: PMC5378161.
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Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis. Circ Arrhythm Electrophysiol. 2017 01; 10(1). Tzou WS, Tung R, Frankel DS, Vaseghi M, Bunch TJ, Di Biase L, Tholakanahalli VN, Lakkireddy D, Dickfeld T, Saliaris A, Weiss JP, Mathuria N, Tedrow U, Afzal MR, Vergara P, Nagashima K, Patel M, Nakahara S, Vakil K, Burkhardt JD, Tseng CH, Natale A, Shivkumar K, Callans DJ, Stevenson WG, Della Bella P, Marchlinski FE, Sauer WH. PMID: 28082527.
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Anatomy for Ventricular Tachycardia Ablation in Structural Heart Disease. Card Electrophysiol Clin. 2017 03; 9(1):11-24. Bradfield JS, Shivkumar K. PMID: 28167079.
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Cardiac sympathetic innervation via middle cervical and stellate ganglia and antiarrhythmic mechanism of bilateral stellectomy. Am J Physiol Heart Circ Physiol. 2017 Mar 01; 312(3):H392-H405. Irie T, Yamakawa K, Hamon D, Nakamura K, Shivkumar K, Vaseghi M. PMID: 28011590; PMCID: PMC5402012.
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Prognostic Impact of the Timing of Recurrence of Infarct-Related Ventricular Tachycardia After Catheter Ablation. Circ Arrhythm Electrophysiol. 2016 12; 9(12). Siontis KC, Kim HM, Stevenson WG, Fujii A, Bella PD, Vergara P, Shivkumar K, Tung R, Do DH, Daoud EG, Okabe T, Zeppenfeld K, Riva Silva M, Hindricks G, Arya A, Weber A, Kuck KH, Metzner A, Mathew S, Riedl J, Yokokawa M, Jongnarangsin K, Latchamsetty R, Morady F, Bogun FM. PMID: 27923805; PMCID: PMC5823603.
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Sex and Catheter Ablation for Ventricular Tachycardia: An International Ventricular Tachycardia Ablation Center Collaborative Group Study. JAMA Cardiol. 2016 11 01; 1(8):938-944. Frankel DS, Tung R, Santangeli P, Tzou WS, Vaseghi M, Di Biase L, Nagashima K, Tedrow U, Bunch TJ, Tholakanahalli VN, Dendi R, Reddy M, Lakkireddy D, Dickfeld T, Weiss JP, Mathuria N, Vergara P, Patel M, Nakahara S, Vakil K, Sauer WH, Callans DJ, Natale A, Stevenson WG, Della Bella P, Shivkumar K, Marchlinski FE. PMID: 27556589.
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Natriuretic peptides and peripheral autonomic neurotransmission: back to the A, B, and C's. Cardiovasc Res. 2016 12; 112(3):619-621. Ajijola OA, Shivkumar K, Habecker BA. PMID: 27979809; PMCID: PMC5157139.
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Vagal stimulation targets select populations of intrinsic cardiac neurons to control neurally induced atrial fibrillation. Am J Physiol Heart Circ Physiol. 2016 11 01; 311(5):H1311-H1320. Salavatian S, Beaumont E, Longpré JP, Armour JA, Vinet A, Jacquemet V, Shivkumar K, Ardell JL. PMID: 27591222; PMCID: PMC5130494.
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Directional Influences of Ventricular Activation on Myocardial Scar Characterization: Voltage Mapping With Multiple Wavefronts During Ventricular Tachycardia Ablation. Circ Arrhythm Electrophysiol. 2016 08; 9(8). Tung R, Josephson ME, Bradfield JS, Shivkumar K. PMID: 27516464.
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Characterization of the epicardial substrate for catheter ablation of Brugada syndrome. Heart Rhythm. 2016 11; 13(11):2151-2158. Zhang P, Tung R, Zhang Z, Sheng X, Liu Q, Jiang R, Sun Y, Chen S, Yu L, Ye Y, Fu G, Shivkumar K, Jiang C. PMID: 27453126.
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Cardiac autonomic control in health and disease. J Physiol. 2016 07 15; 594(14):3851-2. Shivkumar K, Ardell JL. PMID: 27417670; PMCID: PMC4945710.
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Novel approach to intraprocedural cardiac tamponade: Dual-site drainage with continuous suction. Heart Rhythm. 2016 10; 13(10):2091-4. Macias C, Shivkumar K, Tung R. PMID: 27424076.
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Scar voltage threshold determination using ex vivo magnetic resonance imaging integration in a porcine infarct model: Influence of interelectrode distances and three-dimensional spatial effects of scar. Heart Rhythm. 2016 10; 13(10):1993-2002. Tung R, Kim S, Yagishita D, Vaseghi M, Ennis DB, Ouadah S, Ajijola OA, Bradfield JS, Mahapatra S, Finn P, Shivkumar K. PMID: 27392944.
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MY APPROACH to selecting patients for videoscopic cardiac sympathetic denervation (CSD)⁎. Trends Cardiovasc Med. 2016 11; 26(8):735-736. Shivkumar K. PMID: 27553819.
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Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics. J Physiol. 2016 07 15; 594(14):3911-54. Shivkumar K, Ajijola OA, Anand I, Armour JA, Chen PS, Esler M, De Ferrari GM, Fishbein MC, Goldberger JJ, Harper RM, Joyner MJ, Khalsa SS, Kumar R, Lane R, Mahajan A, Po S, Schwartz PJ, Somers VK, Valderrabano M, Vaseghi M, Zipes DP. PMID: 27114333; PMCID: PMC4945719.
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Usefulness of His Bundle Pacing to Achieve Electrical Resynchronization in Patients With Complete Left Bundle Branch Block and the Relation Between Native QRS Axis, Duration, and Normalization. Am J Cardiol. 2016 08 15; 118(4):527-34. Teng AE, Lustgarten DL, Vijayaraman P, Tung R, Shivkumar K, Wagner GS, Ajijola OA. PMID: 27344272; PMCID: PMC4976011.
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Ablating atrial fibrillation: A translational science perspective for clinicians. Heart Rhythm. 2016 09; 13(9):1868-77. Weiss JN, Qu Z, Shivkumar K. PMID: 27241354; PMCID: PMC4996702.
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Pathological effects of chronic myocardial infarction on peripheral neurons mediating cardiac neurotransmission. Auton Neurosci. 2016 05; 197:34-40. Nakamura K, Ajijola OA, Aliotta E, Armour JA, Ardell JL, Shivkumar K. PMID: 27209472; PMCID: PMC4903881.
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A New Combined Parameter to Predict Premature Ventricular Complexes Induced Cardiomyopathy: Impact and Recognition of Epicardial Origin. J Cardiovasc Electrophysiol. 2016 06; 27(6):709-17. Hamon D, Blaye-Felice MS, Bradfield JS, Chaachoui N, Tung R, Elayi CS, Vaseghi M, Dhanjal TS, Boyle NG, Maury P, Shivkumar K, Lellouche N. PMID: 26924618.
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Catheter ablation of ventricular tachycardia: Lessons learned from past clinical trials and implications for future clinical trials. Heart Rhythm. 2016 08; 13(8):1748-54. Pokorney SD, Friedman DJ, Calkins H, Callans DJ, Daoud EG, Della-Bella P, Jackson KP, Shivkumar K, Saba S, Sapp J, Stevenson WG, Al-Khatib SM. PMID: 27050910; PMCID: PMC5070490.
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Role of Bilateral Sympathectomy in the Treatment of Refractory Ventricular Arrhythmias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy. Circ Arrhythm Electrophysiol. 2016 Apr; 9(4):e003713. Te Riele AS, Ajijola OA, Shivkumar K, Tandri H. PMID: 27030701; PMCID: PMC5087324.
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Cardiac sympathetic denervation for intractable ventricular arrhythmias in Chagas disease. Heart Rhythm. 2016 07; 13(7):1388-94. Saenz LC, Corrales FM, Bautista W, Traina M, Meymandi S, Rodriguez DA, Tellez LJ, Vaseghi M, Garcia F, Shivkumar K, Bradfield JS. PMID: 26969783.
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Ventricular Tachycardia Ablation in the Presence of Left Ventricular Thrombus: Safety and Efficacy. J Cardiovasc Electrophysiol. 2016 Apr; 27(4):453-9. Rao HB, Yu R, Chitnis N, DO D, Boyle NG, Shivkumar K, Bradfield JS. PMID: 26643285.
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Arrhythmogenic Right Ventricular Cardiomyopathy: Electroarchitecture of the Substrate. HeartRhythm Case Rep. 2016 Jan 01; 2(1):47-51. Watanabe A, Seki A, Fishbein MC, Shivkumar K, Vaseghi M. PMID: 26955520; PMCID: PMC4778089.
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Myocardial infarction induces structural and functional remodelling of the intrinsic cardiac nervous system. J Physiol. 2016 Jan 15; 594(2):321-41. Rajendran PS, Nakamura K, Ajijola OA, Vaseghi M, Armour JA, Ardell JL, Shivkumar K. PMID: 26572244; PMCID: PMC4713729.
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Central vs. peripheral neuraxial sympathetic control of porcine ventricular electrophysiology. Am J Physiol Regul Integr Comp Physiol. 2016 Mar 01; 310(5):R414-21. Yamakawa K, Howard-Quijano K, Zhou W, Rajendran P, Yagishita D, Vaseghi M, Ajijola OA, Armour JA, Shivkumar K, Ardell JL, Mahajan A. PMID: 26661096; PMCID: PMC4796738.
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Long-term clinical outcomes of focal impulse and rotor modulation for treatment of atrial fibrillation: A multicenter experience. Heart Rhythm. 2016 Mar; 13(3):636-41. Buch E, Share M, Tung R, Benharash P, Sharma P, Koneru J, Mandapati R, Ellenbogen KA, Shivkumar K. PMID: 26498260; PMCID: PMC4762742.
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Response to Letter by Jalife et al Regarding Article, "Quantitative Analysis of Localized Sources Identified by Focal Impulse and Rotor Mapping in Atrial Fibrillation". Circ Arrhythm Electrophysiol. 2015 Oct; 8(5):1299-300. Buch E, Benharash P, Frank P, Share M, Tung R, Shivkumar K, Mandapati R, Mandapati R. PMID: 26487628; PMCID: PMC4661436.
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Mortality prediction using a modified Seattle Heart Failure Model may improve patient selection for ventricular tachycardia ablation. Am Heart J. 2015 Dec; 170(6):1099-104. Vakil KP, Roukoz H, Tung R, Levy WC, Anand IS, Shivkumar K, Rector TS, Vaseghi M, Tholakanahalli V. PMID: 26678631.
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Catheter Ablation of Atrial Fibrillation: Advent of Second-Generation Technologies. J Am Coll Cardiol. 2015 Sep 22; 66(12):1361-3. Buch E, Shivkumar K. PMID: 26383723; PMCID: PMC4659817.
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Vagal nerve stimulation activates vagal afferent fibers that reduce cardiac efferent parasympathetic effects. Am J Physiol Heart Circ Physiol. 2015 Nov; 309(9):H1579-90. Yamakawa K, Rajendran PS, Takamiya T, Yagishita D, So EL, Mahajan A, Shivkumar K, Vaseghi M. PMID: 26371172; PMCID: PMC4666973.
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Prolonged high-power endocardial ablation of epicardial microreentrant VT from the LV summit in a patient with nonischemic cardiomyopathy. HeartRhythm Case Rep. 2015 Nov; 1(6):464-468. Romero J, Ajijola OA, Boyle N, Shivkumar K, Tung R. PMID: 28491608; PMCID: PMC5419725.
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Hyper-response to cardiac resynchronization with permanent His bundle pacing: Is parahisian pacing sufficient? HeartRhythm Case Rep. 2015 Nov; 1(6):429-433. Ajijola OA, Romero J, Vorobiof G, Suh WM, Shivkumar K, Tung R. PMID: 27722091; PMCID: PMC5053391.
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Targeted stellate decentralization: Implications for sympathetic control of ventricular electrophysiology. Heart Rhythm. 2016 Jan; 13(1):282-8. Buckley U, Yamakawa K, Takamiya T, Andrew Armour J, Shivkumar K, Ardell JL. PMID: 26282244; PMCID: PMC4698240.
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Incidence of abnormal positron emission tomography in patients with unexplained cardiomyopathy and ventricular arrhythmias: The potential role of occult inflammation in arrhythmogenesis. Heart Rhythm. 2015 Dec; 12(12):2488-98. Tung R, Bauer B, Schelbert H, Lynch JP, Auerbach M, Gupta P, Schiepers C, Chan S, Ferris J, Barrio M, Ajijola O, Bradfield J, Shivkumar K. PMID: 26272522; PMCID: PMC4656080.
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Autonomic Regulation Therapy in Heart Failure. Curr Heart Fail Rep. 2015 Aug; 12(4):284-93. Buckley U, Shivkumar K, Ardell JL. PMID: 26054327; PMCID: PMC4607027.
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Cardiac innervation and sudden cardiac death. Circ Res. 2015 Jun 05; 116(12):2005-19. Fukuda K, Kanazawa H, Aizawa Y, Ardell JL, Shivkumar K. PMID: 26044253; PMCID: PMC4465108.
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Freedom from recurrent ventricular tachycardia after catheter ablation is associated with improved survival in patients with structural heart disease: An International VT Ablation Center Collaborative Group study. Heart Rhythm. 2015 Sep; 12(9):1997-2007. Tung R, Vaseghi M, Frankel DS, Vergara P, Di Biase L, Nagashima K, Yu R, Vangala S, Tseng CH, Choi EK, Khurshid S, Patel M, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Vakil K, Tedrow U, Burkhardt JD, Tholakanahalli VN, Saliaris A, Dickfeld T, Weiss JP, Bunch TJ, Reddy M, Kanmanthareddy A, Callans DJ, Lakkireddy D, Natale A, Marchlinski F, Stevenson WG, Della Bella P, Shivkumar K. PMID: 26031376; PMCID: PMC4549209.
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Stress-induced cardiac arrhythmias: The heart-brain interaction. Trends Cardiovasc Med. 2016 Jan; 26(1):78-80. Buckley U, Shivkumar K. PMID: 26051207; PMCID: PMC4662914.
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Implantable cardioverter defibrillators: even better than we thought? Eur Heart J. 2015 Jul 07; 36(26):1646-8. Buckley U, Shivkumar K. PMID: 25943537; PMCID: PMC4493325.
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Device-based autonomic modulation in arrhythmia patients: the role of vagal nerve stimulation. Curr Treat Options Cardiovasc Med. 2015 May; 17(5):379. Huang WA, Shivkumar K, Vaseghi M. PMID: 25894588; PMCID: PMC4662680.
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Multicenter Outcomes for Catheter Ablation of Idiopathic Premature Ventricular Complexes. JACC Clin Electrophysiol. 2015 Jun; 1(3):116-123. Latchamsetty R, Yokokawa M, Morady F, Kim HM, Mathew S, Tilz R, Kuck KH, Nagashima K, Tedrow U, Stevenson WG, Yu R, Tung R, Shivkumar K, Sarrazin JF, Arya A, Hindricks G, Vunnam R, Dickfeld T, Daoud EG, Oza NM, Bogun F. PMID: 29759353.
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Quantitative analysis of localized sources identified by focal impulse and rotor modulation mapping in atrial fibrillation. Circ Arrhythm Electrophysiol. 2015 Jun; 8(3):554-61. Benharash P, Buch E, Frank P, Share M, Tung R, Shivkumar K, Mandapati R. PMID: 25873718; PMCID: PMC4655205.
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Epicardial Ablation of Ventricular Tachycardia. Methodist Debakey Cardiovasc J. 2015 Apr-Jun; 11(2):129-34. Tung R, Shivkumar K. PMID: 26306131; PMCID: PMC4547668.
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Detecting and monitoring arrhythmia recurrence following catheter ablation of atrial fibrillation. Front Physiol. 2015; 6:90. Ajijola OA, Boyle NG, Shivkumar K. PMID: 25870562; PMCID: PMC4376077.
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Reply to the Editor-More Awarenessless Risk-Interpretation of Ablation Risk Caused by Coronary Arterial Anatomy. Heart Rhythm. 2015 Jul; 12(7):e66-7. Mao J, Moriarty JM, Mandapati R, Boyle NG, Shivkumar K, Vaseghi M. PMID: 25814410; PMCID: PMC4659813.
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Modified wideband three-dimensional late gadolinium enhancement MRI for patients with implantable cardiac devices. Magn Reson Med. 2016 Feb; 75(2):572-84. Rashid S, Rapacchi S, Shivkumar K, Plotnik A, Finn JP, Hu P. PMID: 25772155; PMCID: PMC4661130.
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Relationship between sinus rhythm late activation zones and critical sites for scar-related ventricular tachycardia: systematic analysis of isochronal late activation mapping. Circ Arrhythm Electrophysiol. 2015 Apr; 8(2):390-9. Irie T, Yu R, Bradfield JS, Vaseghi M, Buch EF, Ajijola O, Macias C, Fujimura O, Mandapati R, Boyle NG, Shivkumar K, Tung R. PMID: 25740836; PMCID: PMC4695215.
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Augmentation of cardiac sympathetic tone by percutaneous low-level stellate ganglion stimulation in humans: a feasibility study. Physiol Rep. 2015 Mar; 3(3). Ajijola OA, Howard-Quijano K, Scovotti J, Vaseghi M, Lee C, Mahajan A, Shivkumar K. PMID: 25804262; PMCID: PMC4393162.
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Remodeling of stellate ganglion neurons after spatially targeted myocardial infarction: Neuropeptide and morphologic changes. Heart Rhythm. 2015 May; 12(5):1027-35. Ajijola OA, Yagishita D, Reddy NK, Yamakawa K, Vaseghi M, Downs AM, Hoover DB, Ardell JL, Shivkumar K. PMID: 25640636; PMCID: PMC4411181.
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Neuraxial modulation for treatment of VT storm. J Biomed Res. 2015 Jan; 29(1):56-60. Tung R, Shivkumar K. PMID: 25745476; PMCID: PMC4342436.
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Sympathetic nerve stimulation, not circulating norepinephrine, modulates T-peak to T-end interval by increasing global dispersion of repolarization. Circ Arrhythm Electrophysiol. 2015 Feb; 8(1):174-85. Yagishita D, Chui RW, Yamakawa K, Rajendran PS, Ajijola OA, Nakamura K, So EL, Mahajan A, Shivkumar K, Vaseghi M. PMID: 25532528; PMCID: PMC4405126.
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Catheter ablation of accessory pathways near the coronary sinus: value of defining coronary arterial anatomy. Heart Rhythm. 2015 Mar; 12(3):508-514. Mao J, Moriarty JM, Mandapati R, Boyle NG, Shivkumar K, Vaseghi M. PMID: 25485779; PMCID: PMC4659814.
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Cardiac resynchronization therapy-induced proarrhythmia: understanding preferential conduction within myocardial scars. Circ Arrhythm Electrophysiol. 2014 Dec; 7(6):1000-2. Bradfield JS, Shivkumar K. PMID: 25516575; PMCID: PMC4661435.
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Arrhythmias in the Heart Transplant Patient. Arrhythm Electrophysiol Rev. 2014 Nov; 3(3):149-55. Hamon D, Taleski J, Vaseghi M, Shivkumar K, Boyle NG. PMID: 26835083; PMCID: PMC4711495.
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Catheter ablation of scar-based ventricular tachycardia: Relationship of procedure duration to outcomes and hospital mortality. Heart Rhythm. 2015 Jan; 12(1):86-94. Yu R, Ma S, Tung R, Stevens S, Macias C, Bradfield J, Buch E, Vaseghi M, Fujimura O, Gornbein J, Mandapati R, Shivkumar K, Boyle NG. PMID: 25285644; PMCID: PMC4282181.
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EHRA/HRS/APHRS expert consensus on ventricular arrhythmias. Europace. 2014 09; 16(9):1257-83. Pedersen CT, Kay GN, Kalman J, Borggrefe M, Della-Bella P, Dickfeld T, Dorian P, Huikuri H, Kim YH, Knight B, Marchlinski F, Ross D, Sacher F, Sapp J, Shivkumar K, Soejima K, Tada H, Alexander ME, Triedman JK, Yamada T, Kirchhof P, Lip GY, Kuck KH, Mont L, Haines D, Indik J, Dimarco J, Exner D, Iesaka Y, Savelieva I. PMID: 25172618.
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EHRA/HRS/APHRS expert consensus on ventricular arrhythmias. Heart Rhythm. 2014 Oct; 11(10):e166-96. Pedersen CT, Kay GN, Kalman J, Borggrefe M, Della-Bella P, Dickfeld T, Dorian P, Huikuri H, Kim YH, Knight B, Marchlinski F, Ross D, Sacher F, Sapp J, Shivkumar K, Soejima K, Tada H, Alexander ME, Triedman JK, Yamada T, Kirchhof P, Lip GY, Kuck KH, Mont L, Haines D, Indik J, Dimarco J, Exner D, Iesaka Y, Savelieva I, EP-Europace, UK. PMID: 25179489.
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Biophysical parameters during radiofrequency catheter ablation of scar-mediated ventricular tachycardia: epicardial and endocardial applications via manual and magnetic navigation. J Cardiovasc Electrophysiol. 2014 Nov; 25(11):1165-73. Bourke T, Buch E, Mathuria N, Michowitz Y, Yu R, Mandapati R, Shivkumar K, Tung R. PMID: 24946895; PMCID: PMC4282185.
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Initial independent outcomes from focal impulse and rotor modulation ablation for atrial fibrillation: multicenter FIRM registry. J Cardiovasc Electrophysiol. 2014 Sep; 25(9):921-929. Miller JM, Kowal RC, Swarup V, Daubert JP, Daoud EG, Day JD, Ellenbogen KA, Hummel JD, Baykaner T, Krummen DE, Narayan SM, Reddy VY, Shivkumar K, Steinberg JS, Wheelan KR. PMID: 24948520; PMCID: PMC4282180.
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Repolarization parameters are associated with mortality in chagas disease patients in the United States. Indian Pacing Electrophysiol J. 2014 Jul; 14(4):171-80. Bradfield J, Woodbury B, Traina M, Hernandez S, Sanchez D, Wachsner R, Shivkumar K, Meymandi S. PMID: 25057218; PMCID: PMC4100080.
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Electrophysiological effects of right and left vagal nerve stimulation on the ventricular myocardium. Am J Physiol Heart Circ Physiol. 2014 Sep 01; 307(5):H722-31. Yamakawa K, So EL, Rajendran PS, Hoang JD, Makkar N, Mahajan A, Shivkumar K, Vaseghi M. PMID: 25015962; PMCID: PMC4187397.
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Cardiac involvement in sarcoidosis: evolving concepts in diagnosis and treatment. Semin Respir Crit Care Med. 2014 Jun; 35(3):372-90. Lynch JP, Hwang J, Bradfield J, Fishbein M, Shivkumar K, Tung R. PMID: 25007089; PMCID: PMC4253029.
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Radiofrequency ablation of drug refractory ventricular tachycardia related to cocaine use: a feasibility, safety, and efficacy study. J Cardiovasc Electrophysiol. 2014 Jul; 25(7):739-46. Lakkireddy D, Kanmanthareddy A, Biria M, Madhu Reddy Y, Pillarisetti J, Mahapatra S, Berenbom L, Chinitz L, Atkins D, Bommana S, Tung R, DI Biase L, Shivkumar K, Natale A. PMID: 24724798; PMCID: PMC4253032.
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Renal denervation for refractory ventricular arrhythmias. Trends Cardiovasc Med. 2014 Jul; 24(5):206-13. Bradfield JS, Vaseghi M, Shivkumar K. PMID: 25017919; PMCID: PMC4254550.
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Comparative safety of periablation anticoagulation strategies for atrial fibrillation: data from a large multicenter study. Pacing Clin Electrophysiol. 2014 Jun; 37(6):665-73. Arshad A, Johnson CK, Mittal S, Buch E, Hamam I, Tran T, Shaw RE, Musat D, Preminger M, Sichrovsky T, Herweg B, Shivkumar K, Hummel J, Steinberg JS. PMID: 24797604; PMCID: PMC4253027.
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A Case Of Difficult Epicardial Access For Ablation Of Ventricular Tachcyardia. J Atr Fibrillation. 2014 Apr-May; 6(6):1045. Stevens SM, Tung R, Shivkumar K, Bradfield JS. PMID: 27957064; PMCID: PMC5135241.
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Proceedings from the Society of Interventional Radiology Foundation Research Consensus Panel on Renal Sympathetic Denervation. J Vasc Interv Radiol. 2014 Apr; 25(4):497-509. Angle JF, Prince EA, Matsumoto AH, Lohmeier TE, Roberts AM, Misra S, Razavi MK, Katholi RE, Sarin SN, Sica DA, Shivkumar K, Ahrar K. PMID: 24674208.
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Response to letter regarding "Impact of local ablation on inter-connected channels within ventricular scar: mechanistic implications for substrate modification". Circ Arrhythm Electrophysiol. 2014 Apr; 7(2):363. Tung R, Mathuria NS, Nagel R, Mandapati R, Buch EF, Bradfield JS, Vaseghi M, Boyle NG, Shivkumar K. PMID: 24736430.
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Coupling interval variability differentiates ventricular ectopic complexes arising in the aortic sinus of valsalva and great cardiac vein from other sources: mechanistic and arrhythmic risk implications. J Am Coll Cardiol. 2014 May 27; 63(20):2151-2158. Bradfield JS, Homsi M, Shivkumar K, Miller JM. PMID: 24657687; PMCID: PMC4282189.
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Ablation of rotor and focal sources reduces late recurrence of atrial fibrillation compared with trigger ablation alone: extended follow-up of the CONFIRM trial (Conventional Ablation for Atrial Fibrillation With or Without Focal Impulse and Rotor Modulation). J Am Coll Cardiol. 2014 May 06; 63(17):1761-8. Narayan SM, Baykaner T, Clopton P, Schricker A, Lalani GG, Krummen DE, Shivkumar K, Miller JM. PMID: 24632280; PMCID: PMC4008643.
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Marshaling the autonomic nervous system for treatment of atrial fibrillation. J Am Coll Cardiol. 2014 May 13; 63(18):1902-3. Rajendran PS, Buch E, Shivkumar K. PMID: 24561143; PMCID: PMC4219829.
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Percutaneous left ventricular assist devices in ventricular tachycardia ablation: multicenter experience. Circ Arrhythm Electrophysiol. 2014 Apr; 7(2):244-50. Reddy YM, Chinitz L, Mansour M, Bunch TJ, Mahapatra S, Swarup V, Di Biase L, Bommana S, Atkins D, Tung R, Shivkumar K, Burkhardt JD, Ruskin J, Natale A, Lakkireddy D. PMID: 24532564; PMCID: PMC4329420.
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Ventricular tachycardia in ischemic heart disease substrates. Indian Heart J. 2014 Jan-Feb; 66 Suppl 1:S24-34. Ajijola OA, Tung R, Shivkumar K. PMID: 24568826; PMCID: PMC4237298.
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Synergistic application of cardiac sympathetic decentralization and comprehensive psychiatric treatment in the management of anxiety and electrical storm. Front Integr Neurosci. 2014; 7:98. Khalsa SS, Shahabi L, Ajijola OA, Bystritsky A, Naliboff BD, Shivkumar K. PMID: 24427121; PMCID: PMC3878030.
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Safety and efficacy of renal denervation as a novel treatment of ventricular tachycardia storm in patients with cardiomyopathy. Heart Rhythm. 2014 Apr; 11(4):541-6. Remo BF, Preminger M, Bradfield J, Mittal S, Boyle N, Gupta A, Shivkumar K, Steinberg JS, Dickfeld T. PMID: 24389229; PMCID: PMC4253025.
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Anesthetic considerations for thoracoscopic sympathetic ganglionectomy to treat ventricular tachycardia storm: a single-center experience. J Cardiothorac Vasc Anesth. 2014 Feb; 28(1):69-75. Methangkool E, Chua JH, Gopinath A, Shivkumar K, Mahajan A. PMID: 24290748; PMCID: PMC4253028.
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Cardiac sympathetic denervation in patients with refractory ventricular arrhythmias or electrical storm: intermediate and long-term follow-up. Heart Rhythm. 2014 Mar; 11(3):360-6. Vaseghi M, Gima J, Kanaan C, Ajijola OA, Marmureanu A, Mahajan A, Shivkumar K. PMID: 24291775; PMCID: PMC4253031.
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Transmural "Scar-to-Scar" Reentrant Ventricular Tachycardia. Indian Pacing Electrophysiol J. 2013 Nov; 13(6):212-6. Bradfield JS, Tung R, Shivkumar K. PMID: 24482562; PMCID: PMC3876580.
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Improved late gadolinium enhancement MR imaging for patients with implanted cardiac devices. Radiology. 2014 Jan; 270(1):269-74. Rashid S, Rapacchi S, Vaseghi M, Tung R, Shivkumar K, Finn JP, Hu P. PMID: 24086074; PMCID: PMC4228714.
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Impact of local ablation on interconnected channels within ventricular scar: mechanistic implications for substrate modification. Circ Arrhythm Electrophysiol. 2013 Dec; 6(6):1131-8. Tung R, Mathuria NS, Nagel R, Mandapati R, Buch EF, Bradfield JS, Vaseghi M, Boyle NG, Shivkumar K. PMID: 24162832; PMCID: PMC3977176.
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Device artifact reduction for magnetic resonance imaging of patients with implantable cardioverter-defibrillators and ventricular tachycardia: late gadolinium enhancement correlation with electroanatomic mapping. Heart Rhythm. 2014 Feb; 11(2):289-98. Stevens SM, Tung R, Rashid S, Gima J, Cote S, Pavez G, Khan S, Ennis DB, Finn JP, Boyle N, Shivkumar K, Hu P. PMID: 24140812; PMCID: PMC3946910.
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Quantitative localization of premature ventricular contractions using myocardial activation ECGI from the standard 12-lead electrocardiogram. J Electrocardiol. 2013 Nov-Dec; 46(6):574-9. van Dam PM, Tung R, Shivkumar K, Laks M. PMID: 24028996.
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Unusual response to entrainment of ventricular tachycardia: in or out? Heart Rhythm. 2014 Apr; 11(4):725-7. Tung R, Shivkumar K. PMID: 24016698.
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Focal myocardial infarction induces global remodeling of cardiac sympathetic innervation: neural remodeling in a spatial context. Am J Physiol Heart Circ Physiol. 2013 Oct 01; 305(7):H1031-40. Ajijola OA, Yagishita D, Patel KJ, Vaseghi M, Zhou W, Yamakawa K, So E, Lux RL, Mahajan A, Shivkumar K. PMID: 23893167; PMCID: PMC3798751.
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Modulation of regional dispersion of repolarization and T-peak to T-end interval by the right and left stellate ganglia. Am J Physiol Heart Circ Physiol. 2013 Oct 01; 305(7):H1020-30. Vaseghi M, Yamakawa K, Sinha A, So EL, Zhou W, Ajijola OA, Lux RL, Laks M, Shivkumar K, Mahajan A. PMID: 23893168; PMCID: PMC3798747.
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Electrical homogenization of ventricular scar by application of collagenase: a novel strategy for arrhythmia therapy. Circ Arrhythm Electrophysiol. 2013 Aug; 6(4):776-83. Yagishita D, Ajijola OA, Vaseghi M, Nsair A, Zhou W, Yamakawa K, Tung R, Mahajan A, Shivkumar K. PMID: 23873142; PMCID: PMC3872289.
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Percutaneous interventricular septal access in a patient with aortic and mitral mechanical valves: a novel technique for catheter ablation of ventricular tachycardia. Heart Rhythm. 2013 Jul; 10(7):1069-73. Vaseghi M, Macias C, Tung R, Shivkumar K. PMID: 23643678; PMCID: PMC3766746.
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Quinidine, a life-saving medication for Brugada syndrome, is inaccessible in many countries. J Am Coll Cardiol. 2013 Jun 11; 61(23):2383-7. Viskin S, Wilde AA, Guevara-Valdivia ME, Daoulah A, Krahn AD, Zipes DP, Halkin A, Shivkumar K, Boyle NG, Adler A, Belhassen B, Schapachnik E, Asrar F, Rosso R. PMID: 23583244.
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Direct or coincidental elimination of stable rotors or focal sources may explain successful atrial fibrillation ablation: on-treatment analysis of the CONFIRM trial (Conventional ablation for AF with or without focal impulse and rotor modulation). J Am Coll Cardiol. 2013 Jul 09; 62(2):138-147. Narayan SM, Krummen DE, Clopton P, Shivkumar K, Miller JM. PMID: 23563126; PMCID: PMC3703494.
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Integrated care for management of ventricular arrhythmias: can a specialized unit and catheter ablation improve mortality? Circulation. 2013 Apr 02; 127(13):1354-6. Tung R, Shivkumar K. PMID: 23547176.
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Tissue voltage discordance during tachycardia versus sinus rhythm: implications for catheter ablation. Heart Rhythm. 2013 Jun; 10(6):800-4. Bradfield JS, Huang W, Tung R, Buch E, Okhovat JP, Fujimura O, Boyle NG, Gornbein J, Ellenbogen KA, Shivkumar K. PMID: 23434619.
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Panoramic electrophysiological mapping but not electrogram morphology identifies stable sources for human atrial fibrillation: stable atrial fibrillation rotors and focal sources relate poorly to fractionated electrograms. Circ Arrhythm Electrophysiol. 2013 Feb; 6(1):58-67. Narayan SM, Shivkumar K, Krummen DE, Miller JM, Rappel WJ. PMID: 23392583; PMCID: PMC3746540.
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Effect of stellate ganglia stimulation on global and regional left ventricular function as assessed by speckle tracking echocardiography. Am J Physiol Heart Circ Physiol. 2013 Mar 15; 304(6):H840-7. Zhou W, Yamakawa K, Benharash P, Ajijola O, Ennis D, Hadaya J, Vaseghi M, Shivkumar K, Mahajan A. PMID: 23335795; PMCID: PMC3602776.
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The value of image integration for epicardial catheter ablation of ventricular tachycardia. JACC Cardiovasc Imaging. 2013 Jan; 6(1):53-5. Tung R, Shivkumar K. PMID: 23328561.
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Our approach to minimize risk of epicardial access: standard techniques with the addition of electroanatomic mapping guidance. J Cardiovasc Electrophysiol. 2013 Jun; 24(6):723-7. Bradfield JS, Tung R, Boyle NG, Buch E, Shivkumar K. PMID: 23279311; PMCID: PMC3696725.
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Functional differences between junctional and extrajunctional adrenergic receptor activation in mammalian ventricle. Am J Physiol Heart Circ Physiol. 2013 Feb 15; 304(4):H579-88. Ajijola OA, Vaseghi M, Zhou W, Yamakawa K, Benharash P, Hadaya J, Lux RL, Mahajan A, Shivkumar K. PMID: 23241324; PMCID: PMC3566483.
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Epicardial ablation of ventricular tachycardia: an institutional experience of safety and efficacy. Heart Rhythm. 2013 Apr; 10(4):490-8. Tung R, Michowitz Y, Yu R, Mathuria N, Vaseghi M, Buch E, Bradfield J, Fujimura O, Gima J, Discepolo W, Mandapati R, Shivkumar K. PMID: 23246598.
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In silico to in vivo: mutation-specific modeling of arrhythmia risk. J Am Coll Cardiol. 2012 Nov 20; 60(21):2192-3. Mandapati R, Shivkumar K. PMID: 23153845.
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Acute termination of human atrial fibrillation by identification and catheter ablation of localized rotors and sources: first multicenter experience of focal impulse and rotor modulation (FIRM) ablation. J Cardiovasc Electrophysiol. 2012 Dec; 23(12):1277-85. Shivkumar K, Ellenbogen KA, Hummel JD, Miller JM, Steinberg JS. PMID: 23130890; PMCID: PMC3524347.
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Catheter ablation of ventricular tachycardia using intracoronary wire mapping and coil embolization: description of a new technique. Heart Rhythm. 2013 Feb; 10(2):292-6. Tholakanahalli VN, Bertog S, Roukoz H, Shivkumar K. PMID: 23089899.
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Epicardial interventions in electrophysiology. Circulation. 2012 Oct 02; 126(14):1752-69. Boyle NG, Shivkumar K. PMID: 23027811; PMCID: PMC4326668.
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Interventions to decrease the morbidity and mortality associated with implantable cardioverter-defibrillator shocks. Curr Opin Crit Care. 2012 Oct; 18(5):432-7. Bradfield JS, Buch E, Shivkumar K. PMID: 22889870.
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Advances in ablation of ventricular tachycardia in nonischemic cardiomyopathy. Curr Cardiol Rep. 2012 Oct; 14(5):577-83. Mathuria N, Tung R, Shivkumar K. PMID: 22843484; PMCID: PMC3766743.
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Ablation of Post Transplant Atrial Flutter and Pseudo-fibrillation Using Magnetic Navigation via a Superior Approach. Indian Pacing Electrophysiol J. 2012 Sep; 12(5):229-32. Tung R, Shivkumar K, Mandapati R. PMID: 23071385; PMCID: PMC3443881.
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The Emerging Role of Epicardial Ablation. Card Electrophysiol Clin. 2012 Sep; 4(3):425-37. Di Biase L, Santangeli P, Bai R, Tung R, David Burkhardt J, Shivkumar K, Natale A. PMID: 26939962.
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Atrial Fibrillation Ablation: Do We Really Need Preprocedural Imaging? Card Electrophysiol Clin. 2012 Sep; 4(3):305-15. Bourke T, Moriarty J, Boyle NG, Shivkumar K. PMID: 26939950.
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Neuraxial modulation for ventricular arrhythmias: a new hope. Heart Rhythm. 2012 Nov; 9(11):1888-9. Vaseghi M, Shivkumar K. PMID: 23036525.
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Extracardiac neural remodeling in humans with cardiomyopathy. Circ Arrhythm Electrophysiol. 2012 Oct; 5(5):1010-116. Ajijola OA, Wisco JJ, Lambert HW, Mahajan A, Stark E, Fishbein MC, Shivkumar K. PMID: 22923270; PMCID: PMC3529182.
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Unipolar and bipolar electrogram characteristics predict exit block during pulmonary vein antral isolation. Pacing Clin Electrophysiol. 2012 Nov; 35(11):1294-301. Michowitz Y, Buch E, Bourke T, Tung R, Bradfield J, Mathuria N, Boyle NG, Shivkumar K. PMID: 22897649.
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Narrow QRS complex tachycardia: what is the mechanism? Heart Rhythm. 2013 Sep; 10(9):1402-4. Vaseghi M, Fujimura O, Shivkumar K. PMID: 22885663; PMCID: PMC3758399.
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Bilateral cardiac sympathetic denervation: why, who and when? Expert Rev Cardiovasc Ther. 2012 Aug; 10(8):947-9. Ajijola OA, Vaseghi M, Mahajan A, Shivkumar K. PMID: 23030281; PMCID: PMC3551540.
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Treatment of atrial fibrillation by the ablation of localized sources: CONFIRM (Conventional Ablation for Atrial Fibrillation With or Without Focal Impulse and Rotor Modulation) trial. J Am Coll Cardiol. 2012 Aug 14; 60(7):628-36. Narayan SM, Krummen DE, Shivkumar K, Clopton P, Rappel WJ, Miller JM. PMID: 22818076; PMCID: PMC3416917.
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Catheter ablation of atrial fibrillation. Circulation. 2012 Jul 10; 126(2):223-9. Tung R, Buch E, Shivkumar K. PMID: 22777665.
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Catheter ablation of typical atrial flutter in severe pulmonary hypertension. J Cardiovasc Electrophysiol. 2012 Nov; 23(11):1185-90. Bradfield J, Shapiro S, Finch W, Tung R, Boyle NG, Buch E, Mathuria N, Mandapati R, Shivkumar K, Bersohn M. PMID: 22734591.
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Ventricular tachycardia from remote blunt chest trauma: combined epicardial-endocardial right ventricular substrate characterization. Pacing Clin Electrophysiol. 2012 May; 35(5):e127-30. Michowitz Y, Tung R, Athill C, Shivkumar K. PMID: 22564003.
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Catheter ablation utilizing remote magnetic navigation: a review of applications and outcomes. Pacing Clin Electrophysiol. 2012 Aug; 35(8):1021-34. Bradfield J, Tung R, Mandapati R, Boyle NG, Shivkumar K. PMID: 22510160.
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Sympathetic innervation of the anterior left ventricular wall by the right and left stellate ganglia. Heart Rhythm. 2012 Aug; 9(8):1303-9. Vaseghi M, Zhou W, Shi J, Ajijola OA, Hadaya J, Shivkumar K, Mahajan A. PMID: 22465457.
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Neural remodeling and myocardial infarction: the stellate ganglion as a double agent. J Am Coll Cardiol. 2012 Mar 06; 59(10):962-4. Ajijola OA, Shivkumar K. PMID: 22381433; PMCID: PMC3536484.
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The emerging role of cardiac resynchronization therapy in milder heart failure: are we implanting too late for response? Curr Heart Fail Rep. 2012 Mar; 9(1):51-6. Bradfield J, Boyle NG, Mandapati R, Shivkumar K. PMID: 22135184.
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Sympathetic stimulation increases dispersion of repolarization in humans with myocardial infarction. Am J Physiol Heart Circ Physiol. 2012 May 01; 302(9):H1838-46. Vaseghi M, Lux RL, Mahajan A, Shivkumar K. PMID: 22345568; PMCID: PMC3362058.
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Functional pace-mapping responses for identification of targets for catheter ablation of scar-mediated ventricular tachycardia. Circ Arrhythm Electrophysiol. 2012 Apr; 5(2):264-72. Tung R, Mathuria N, Michowitz Y, Yu R, Buch E, Bradfield J, Mandapati R, Wiener I, Boyle N, Shivkumar K. PMID: 22333344; PMCID: PMC4334590.
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Pleuropericardial fistula formation after prior epicardial catheter ablation for ventricular tachycardia. Circ Arrhythm Electrophysiol. 2012 Feb; 5(1):e18-9. Mathuria N, Buch E, Shivkumar K. PMID: 22334435.
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First in vivo use of a capacitive micromachined ultrasound transducer array-based imaging and ablation catheter. J Ultrasound Med. 2012 Feb; 31(2):247-56. Stephens DN, Truong UT, Nikoozadeh A, Oralkan O, Seo CH, Cannata J, Dentinger A, Thomenius K, de la Rama A, Nguyen T, Lin F, Khuri-Yakub P, Mahajan A, Shivkumar K, O'Donnell M, Sahn DJ. PMID: 22298868; PMCID: PMC3420825.
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Bilateral cardiac sympathetic denervation for the management of electrical storm. J Am Coll Cardiol. 2012 Jan 03; 59(1):91-2. Ajijola OA, Lellouche N, Bourke T, Tung R, Ahn S, Mahajan A, Shivkumar K. PMID: 22192676; PMCID: PMC3470807.
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How to target postablation perimitral flutter: valve isthmus or PV triggers? J Cardiovasc Electrophysiol. 2012 Feb; 23(2):145-6. Discepolo W, Buch E, Shivkumar K. PMID: 22049914.
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A new electrocardiographic marker for sympathetic nerve stimulation: modulation of repolarization by stimulation of stellate ganglia. J Electrocardiol. 2011 Nov-Dec; 44(6):694-9. Ramirez RJ, Ajijola OA, Zhou W, Holmström B, Lüning H, Laks MM, Shivkumar K, Mahajan A. PMID: 21917265.
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Managing patients with ICD shocks and programming tachycardia therapies during acute heart failure syndromes. Heart Fail Rev. 2011 Sep; 16(5):449-56. Bradfield J, Tung R, Boyle NG, Shivkumar K. PMID: 21451976; PMCID: PMC3139863.
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Imaging cardiac arrhythmias. Sci Transl Med. 2011 Aug 31; 3(98):98fs2. Shivkumar K, Narayan SM. PMID: 21885402; PMCID: PMC3391184.
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Wide complex tachycardia with a unique mode of termination: what is the mechanism? Pacing Clin Electrophysiol. 2012 Jan; 35(1):97-9. Michowitz Y, Mathuria N, Shivkumar K, Mandapati R. PMID: 21819431.
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The Cardiac Atlas Project--an imaging database for computational modeling and statistical atlases of the heart. Bioinformatics. 2011 Aug 15; 27(16):2288-95. Fonseca CG, Backhaus M, Bluemke DA, Britten RD, Chung JD, Cowan BR, Dinov ID, Finn JP, Hunter PJ, Kadish AH, Lee DC, Lima JA, Medrano-Gracia P, Shivkumar K, Suinesiaputra A, Tao W, Young AA. PMID: 21737439; PMCID: PMC3150036.
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The feasibility of using thermal strain imaging to regulate energy delivery during intracardiac radio-frequency ablation. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Jul; 58(7):1406-17. Seo CH, Stephens DN, Cannata J, Dentinger A, Lin F, Park S, Wildes D, Thomenius KE, Chen P, Nguyen T, de La Rama A, Jeong JS, Mahajan A, Shivkumar K, Nikoozadeh A, Oralkan O, Truong U, Sahn DJ, Khuri-Yakub PT, O'Donnell M. PMID: 21768025; PMCID: PMC3177537.
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A 10-Fr ultrasound catheter with integrated micromotor for 4-D intracardiac echocardiography. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Jul; 58(7):1478-91. Lee W, Griffin W, Wildes D, Buckley D, Topka T, Chodakauskas T, Langer M, Calisti S, Bergstøl S, Malacrida JP, Lanteri F, Maffre J, McDaniel B, Shivkumar K, Cummings J, Callans D, Silvestry F, Packer D. PMID: 21768032.
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Ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy: arrhythmia-free survival after endo-epicardial substrate based mapping and ablation. Circ Arrhythm Electrophysiol. 2011 Aug; 4(4):478-85. Bai R, Di Biase L, Shivkumar K, Mohanty P, Tung R, Santangeli P, Saenz LC, Vacca M, Verma A, Khaykin Y, Mohanty S, Burkhardt JD, Hongo R, Beheiry S, Dello Russo A, Casella M, Pelargonio G, Santarelli P, Sanchez J, Tondo C, Natale A. PMID: 21665983.
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Catheter ablation of ventricular tachycardia. Circulation. 2011 May 24; 123(20):2284-8. Tung R, Boyle NG, Shivkumar K. PMID: 21606407.
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Hybrid techniques and neuraxial modulation for treatment of ventricular tachycardia. Future Cardiol. 2011 May; 7(3):273-6. Bourke T, Mathuria N, Michowitz Y, Shivkumar K. PMID: 21627467.
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Relationship between mechanical and electrical remodelling in patients with cardiac resynchronization implanted defibrillators. Europace. 2011 Aug; 13(8):1180-7. Lellouche N, De Diego C, Boyle NG, Wiener I, Akopyan G, Child JS, Shivkumar K. PMID: 21486911; PMCID: PMC3148818.
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Calming the storm by sympatholysis. Indian Pacing Electrophysiol J. 2011 Mar 25; 11(2):31-3. Francis J, Bourke T, Shivkumar K. PMID: 21468246; PMCID: PMC3063612.
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Safety and outcomes of cryoablation for ventricular tachyarrhythmias: results from a multicenter experience. Heart Rhythm. 2011 Jul; 8(7):968-74. Di Biase L, Al-Ahamad A, Santangeli P, Hsia HH, Sanchez J, Bai R, Bailey S, Horton R, Gallinghouse GJ, Burkhardt DJ, Lakkireddy D, Yang Y, Badhwar N, Scheinman M, Tung R, Dello Russo A, Pelargonio G, Casella M, Tomassoni G, Shivkumar K, Natale A. PMID: 21376835.
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Defibrillation threshold testing fails to show clinical benefit during long-term follow-up of patients undergoing cardiac resynchronization therapy defibrillator implantation. Europace. 2011 May; 13(5):683-8. Michowitz Y, Lellouche N, Contractor T, Bourke T, Wiener I, Buch E, Boyle N, Bersohn M, Shivkumar K. PMID: 21252192; PMCID: PMC3081253.
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Assessment of His-Purkinje reserve: what is the mechanism of block? Heart Rhythm. 2012 Mar; 9(3):465-6. Kneller J, Shivkumar K, Tung R. PMID: 21126603.
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Accuracy of combined endocardial and epicardial electroanatomic mapping of a reperfused porcine infarct model: a comparison of electrofield and magnetic systems with histopathologic correlation. Heart Rhythm. 2011 Mar; 8(3):439-47. Tung R, Nakahara S, Ramirez R, Gui D, Magyar C, Lai C, Fishbein M, Shivkumar K. PMID: 21056123.
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Cardiac magnetic resonance imaging: infarct size is an independent predictor of mortality in patients with coronary artery disease. Magn Reson Imaging. 2011 Jan; 29(1):50-6. Bello D, Einhorn A, Kaushal R, Kenchaiah S, Raney A, Fieno D, Narula J, Goldberger J, Shivkumar K, Subacius H, Kadish A. PMID: 20980115.
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Three dissociated rhythms after ablation of an atypical right atrial flutter. J Cardiovasc Electrophysiol. 2011 Apr; 22(4):477. Bradfield J, Buch E, Shivkumar K. PMID: 21489018.
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Electrophysiological differences between the epicardium and the endocardium of the left atrium. Pacing Clin Electrophysiol. 2011 Jan; 34(1):37-46. Michowitz Y, Nakahara S, Bourke T, Buch E, Vaseghi M, De Diego C, Wiener I, Mahajan A, Shivkumar K. PMID: 20946283; PMCID: PMC3018569.
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Arrhythmia recurrence in adult patients with single ventricle physiology following surgical Fontan conversion. Congenit Heart Dis. 2010 Sep-Oct; 5(5):430-4. Aboulhosn J, Williams R, Shivkumar K, Barkowski R, Plunkett M, Miner P, Houser L, Laks H, Reemtsen B, Shannon K, Child J. PMID: 21087427.
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Recurrent irregular tachycardia that consistently terminates on a P wave: what is the mechanism? J Cardiovasc Electrophysiol. 2010 Sep; 21(9):1062-3. Bradfield J, Buch E, Tung R, Shivkumar K. PMID: 20455981.
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Distribution of late potentials within infarct scars assessed by ultra high-density mapping. Heart Rhythm. 2010 Dec; 7(12):1817-24. Nakahara S, Tung R, Ramirez RJ, Gima J, Wiener I, Mahajan A, Boyle NG, Shivkumar K. PMID: 20682358.
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Catheter ablation of ventricular tachycardia. Circulation. 2010 Jul 20; 122(3):e389-91. Tung R, Boyle NG, Shivkumar K. PMID: 20644021; PMCID: PMC2918802.
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Hybrid procedures for epicardial catheter ablation of ventricular tachycardia: value of surgical access. Heart Rhythm. 2010 Nov; 7(11):1635-43. Michowitz Y, Mathuria N, Tung R, Esmailian F, Kwon M, Nakahara S, Bourke T, Boyle NG, Mahajan A, Shivkumar K. PMID: 20633702.
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Idiopathic massive myocardial calcification: a case report and review of the literature. Cardiovasc Pathol. 2011 Mar-Apr; 20(2):e79-83. Shackley BS, Nguyen TP, Shivkumar K, Finn PJ, Fishbein MC. PMID: 20598909.
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Catheter ablation of idiopathic ventricular tachycardia. Circ Arrhythm Electrophysiol. 2010 Jun; 3(3):219-21. Vaseghi M, Shivkumar K. PMID: 20551420; PMCID: PMC3073154.
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Characterization of the arrhythmogenic substrate in ischemic and nonischemic cardiomyopathy implications for catheter ablation of hemodynamically unstable ventricular tachycardia. J Am Coll Cardiol. 2010 May 25; 55(21):2355-65. Nakahara S, Tung R, Ramirez RJ, Michowitz Y, Vaseghi M, Buch E, Gima J, Wiener I, Mahajan A, Boyle NG, Shivkumar K. PMID: 20488307; PMCID: PMC2896717.
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The autonomic stress of sleep: Sleeping the sleep of death. Heart Rhythm. 2010 Aug; 7(8):1075-6. Mandapati R, Shivkumar K. PMID: 20621623.
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Radiofrequency catheter ablation of ventricular arrhythmias in patients with hypertrophic cardiomyopathy: safety and feasibility. Heart Rhythm. 2010 Aug; 7(8):1036-42. Santangeli P, Di Biase L, Lakkireddy D, Burkhardt JD, Pillarisetti J, Michowitz Y, Sanchez JE, Horton R, Mohanty P, Gallinghouse GJ, Dello Russo A, Casella M, Pelargonio G, Santarelli P, Verma A, Narasimhan C, Shivkumar K, Natale A. PMID: 20493276.
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Neuraxial modulation for refractory ventricular arrhythmias: value of thoracic epidural anesthesia and surgical left cardiac sympathetic denervation. Circulation. 2010 Jun 01; 121(21):2255-62. Bourke T, Vaseghi M, Michowitz Y, Sankhla V, Shah M, Swapna N, Boyle NG, Mahajan A, Narasimhan C, Lokhandwala Y, Shivkumar K. PMID: 20479150; PMCID: PMC2896716.
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Coronary sinus fistula: a reason not to implant a transvenous left ventricular lead. Heart Rhythm. 2011 Oct; 8(10):1658. Bradfield J, Mathuria N, Tung R, Shivkumar K. PMID: 20433945.
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Preface. Card Electrophysiol Clin. 2010 Mar; 2(1):xv-xvi. Shivkumar K, Boyle NG. PMID: 28770742.
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ACP Journal Club. Review: Early treatment of a cardiovascular event with nitrates or ACE inhibitors reduces short-term mortality. Ann Intern Med. 2010 Feb 16; 152(4):JC-23. Bradfield J, Shivkumar K. PMID: 20157127.
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Venice Chart International Consensus document on ventricular tachycardia/ventricular fibrillation ablation. J Cardiovasc Electrophysiol. 2010 Mar; 21(3):339-79. Natale A, Raviele A, Al-Ahmad A, Alfieri O, Aliot E, Almendral J, Breithardt G, Brugada J, Calkins H, Callans D, Cappato R, Camm JA, Della Bella P, Guiraudon GM, Haïssaguerre M, Hindricks G, Ho SY, Kuck KH, Marchlinski F, Packer DL, Prystowsky EN, Reddy VY, Ruskin JN, Scanavacca M, Shivkumar K, Soejima K, Stevenson WJ, Themistoclakis S, Verma A, Wilber D, Venice Chart members. PMID: 20082650.
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Miniaturized ultrasound imaging probes enabled by CMUT arrays with integrated frontend electronic circuits. Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:5987-90. Khuri-Yakub BT, Oralkan O, Nikoozadeh A, Wygant IO, Zhuang S, Gencel M, Choe JW, Stephens DN, de la Rama A, Chen P, Lin F, Dentinger A, Wildes D, Thomenius K, Shivkumar K, Mahajan A, Seo CH, O'Donnell M, Truong U, Sahn DJ. PMID: 21097106; PMCID: PMC2997675.
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Distinguishing epicardial fat from scar: analysis of electrograms using high-density electroanatomic mapping in a novel porcine infarct model. Heart Rhythm. 2010 Mar; 7(3):389-95. Tung R, Nakahara S, Ramirez R, Lai C, Fishbein MC, Shivkumar K. PMID: 20185114; PMCID: PMC3766735.
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Nonpharmacologic management of atrial fibrillation: role of the pulmonary veins and posterior left atrium. Heart Rhythm. 2009 Dec; 6(12 Suppl):S5-S11. Shivkumar K, Buch E, Boyle NG. PMID: 19959144; PMCID: PMC2909622.
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Transconduit puncture for catheter ablation of atrial tachycardia in a patient with extracardiac Fontan palliation. Heart Rhythm. 2010 Mar; 7(3):413-6. Dave AS, Aboulhosn J, Child JS, Shivkumar K. PMID: 20097619; PMCID: PMC2852427.
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Ripple mapping: making electroanatomic mapping user-friendly. Heart Rhythm. 2009 Dec; 6(12):1763-4. Tung R, Shivkumar K. PMID: 19959126; PMCID: PMC2825575.
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Intrapericardial balloon placement for prevention of collateral injury during catheter ablation of the left atrium in a porcine model. Heart Rhythm. 2010 Jan; 7(1):81-7. Nakahara S, Ramirez RJ, Buch E, Michowitz Y, Vaseghi M, de Diego C, Boyle NG, Mahajan A, Shivkumar K. PMID: 19914143; PMCID: PMC3766741.
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Improving our understanding of epicardial ventricular tachycardia in nonischemic cardiomyopathy. J Am Coll Cardiol. 2009 Aug 25; 54(9):809-11. Shivkumar K, Tung R. PMID: 19695458; PMCID: PMC2742504.
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Live three-dimensional transesophageal echocardiographic imaging of novel multielectrode ablation catheters. Heart Rhythm. 2010 Apr; 7(4):570-1. Ho JK, Nakahara S, Shivkumar K, Mahajan A. PMID: 19875342; PMCID: PMC4253030.
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Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix. Eur Heart J. 2009 Sep; 30(18):2254-65. Schenke-Layland K, Stock UA, Nsair A, Xie J, Angelis E, Fonseca CG, Larbig R, Mahajan A, Shivkumar K, Fishbein MC, MacLellan WR. PMID: 19561339; PMCID: PMC2742784.
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Alternating cycle length during supraventricular tachycardia: what is the mechanism? J Cardiovasc Electrophysiol. 2009 Sep; 20(9):1071-3. Buch E, Tung R, Shehata M, Shivkumar K. PMID: 19460077; PMCID: PMC3073145.
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In vivo detection of myocardial ischemia in pigs using visible light spectroscopy. Anesth Analg. 2009 Apr; 108(4):1185-92. Ho JK, Liakopoulos OJ, Crowley R, Yezbick AB, Sanchez E, Shivkumar K, Mahajan A. PMID: 19299784.
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Device extraction in adults with congenital heart disease. Pacing Clin Electrophysiol. 2009 Mar; 32(3):340-5. Cesario D, Kedia R, Desai N, Aboulhosn J, Uslan D, Boyle N, Fujimura O, Shehata M, Buch E, Shivkumar K. PMID: 19272064; PMCID: PMC3076067.
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Intracardiac echocardiography during interventional and electrophysiological cardiac catheterization. Circulation. 2009 Feb 03; 119(4):587-96. Hijazi ZM, Shivkumar K, Sahn DJ. PMID: 19188519; PMCID: PMC2761099.
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Experimental studies with a 9F forward-looking intracardiac imaging and ablation catheter. J Ultrasound Med. 2009 Feb; 28(2):207-15. Stephens DN, O'Donnell M, Thomenius K, Dentinger A, Wildes D, Chen P, Shung KK, Cannata J, Khuri-Yakub P, Oralkan O, Mahajan A, Shivkumar K, Sahn DJ. PMID: 19168770; PMCID: PMC2752346.
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Atrial fibrillation in congestive heart failure: current management. Cardiol Clin. 2009 Feb; 27(1):79-93, viii-ix. Boyle NG, Shivkumar K. PMID: 19111766.
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Mode and mechanisms of death after orthotopic heart transplantation. Heart Rhythm. 2009 Apr; 6(4):503-9. Vaseghi M, Lellouche N, Ritter H, Fonarow GC, Patel JK, Moriguchi J, Fishbein MC, Kobashigawa JA, Shivkumar K. PMID: 19324311; PMCID: PMC3766739.
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A family of intracardiac ultrasound imaging devices designed for guidance of electrophysiology ablation procedures. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:1913-7. Sahn DJ, Stephens DN, Cannata JM, Shung K, Oralkan O, Nikoozadeh A, Khuri-Yakub BT, Nguyen H, Chen P, Dentinger AM, Wildes D, Thomenius KE, Mahajan A, Shivkumar K, O'Donnell M. PMID: 19963529; PMCID: PMC2933106.
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Forward-looking intracardiac ultrasound imaging using a 1-D CMUT array integrated with custom front-end electronics. IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Dec; 55(12):2651-60. Nikoozadeh A, Wygant IO, Lin DS, Oralkan O, Ergun AS, Stephens DN, Thomenius KE, Dentinger AM, Wildes D, Akopyan G, Shivkumar K, Mahajan A, Sahn DJ, Khuri-Yakub BT. PMID: 19126489; PMCID: PMC2730563.
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Intra-pericardial balloon retraction of the left atrium: a novel method to prevent esophageal injury during catheter ablation. Heart Rhythm. 2008 Oct; 5(10):1473-5. Buch E, Nakahara S, Shivkumar K. PMID: 18783994; PMCID: PMC2677643.
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Latent atrial fibrillation triggers originating in accessory pathways. Heart Rhythm. 2008 Sep; 5(9):1248-9. Ramirez RJ, Shivkumar K. PMID: 18774097; PMCID: PMC2564987.
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Diagnostic maneuver during narrow-complex tachycardia: what is the arrhythmia mechanism? Heart Rhythm. 2009 May; 6(5):716-7. Buch E, Nakahara S, Shivkumar K. PMID: 19332390; PMCID: PMC2744947.
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The role of the autonomic nervous system in sudden cardiac death. Prog Cardiovasc Dis. 2008 May-Jun; 50(6):404-19. Vaseghi M, Shivkumar K. PMID: 18474284; PMCID: PMC2752648.
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Exploring the potential of pulmonary vein recordings: can they help elucidate mechanisms of paroxysmal atrial fibrillation? Europace. 2008 Jun; 10(6):690-1. Buch E, Shivkumar K. PMID: 18420651.
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Atrial fibrillation and congestive heart failure. Curr Heart Fail Rep. 2008 Mar; 5(1):11-5. Boyle NG, Shivkumar K. PMID: 18460289.
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The acoustic lens design and in vivo use of a multifunctional catheter combining intracardiac ultrasound imaging and electrophysiology sensing. IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Mar; 55(3):602-18. Stephens DN, Cannata J, Liu R, Zhao JZ, Shung KK, Nguyen H, Chia R, Dentinger A, Wildes D, Thomenius KE, Mahajan A, Shivkumar K, Kim K, O'Donnell M, Sahn D. PMID: 18407850; PMCID: PMC2756724.
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Imaging the ascending aorta and aortic arch using transesophageal echocardiography: the expanded aortic view. Echocardiography. 2008 Apr; 25(4):408-13. Mahajan A, Crowley R, Ho JK, Sanchez E, Trivedi P, Natterson B, Shivkumar K. PMID: 18279407.
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Cardiac resynchronization therapy response is associated with shorter duration of atrial fibrillation. Pacing Clin Electrophysiol. 2007 Nov; 30(11):1363-8. Lellouche N, De Diego C, Vaseghi M, Buch E, Cesario DA, Mahajan A, Wiener I, Fonarow GC, Boyle NG, Shivkumar K. PMID: 17976100.
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Development of an electrophysiology (EP)-enabled intracardiac ultrasound catheter integrated with NavX 3-dimensional electrofield mapping for guiding cardiac EP interventions: experimental studies. J Ultrasound Med. 2007 Nov; 26(11):1565-74. Li XK, Pemberton J, Thomenius K, Dentinger A, Lowe RI, Ashraf M, Shung KK, Chia R, Stephens DN, O'Donnell M, Mahajan A, Balaji S, Shivkumar K, Sahn DJ. PMID: 17957051; PMCID: PMC4699423.
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Functional characterization of atrial electrograms in sinus rhythm delineates sites of parasympathetic innervation in patients with paroxysmal atrial fibrillation. J Am Coll Cardiol. 2007 Oct 02; 50(14):1324-31. Lellouche N, Buch E, Celigoj A, Siegerman C, Cesario D, De Diego C, Mahajan A, Boyle NG, Wiener I, Garfinkel A, Shivkumar K. PMID: 17903630.
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Percutaneous epicardial ablation of atrial fibrillation. Heart Rhythm. 2008 Jan; 5(1):152-4. Shivkumar K. PMID: 18053771.
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Left ventricular apical wall motion abnormality is associated with lack of response to cardiac resynchronization therapy in patients with ischemic cardiomyopathy. Heart Rhythm. 2007 Oct; 4(10):1300-5. Buch E, Lellouche N, De Diego C, Vaseghi M, Cesario DA, Fujimura O, Wiener I, Child JS, Boyle NG, Shivkumar K. PMID: 17905335.
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Changes and predictive value of dispersion of repolarization parameters for appropriate therapy in patients with biventricular implantable cardioverter-defibrillators. Heart Rhythm. 2007 Oct; 4(10):1274-83. Lellouche N, De Diego C, Akopyan G, Boyle NG, Mahajan A, Cesario DA, Wiener I, Shivkumar K. PMID: 17905332.
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Irreversible intrapulmonary vascular changes after pulmonary vein stenosis complicating catheter ablation for atrial fibrillation. Cardiovasc Pathol. 2007 Jan-Feb; 16(1):51-5. Yang HM, Lai CK, Patel J, Moore J, Chen PS, Shivkumar K, Fishbein MC. PMID: 17218215.
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Lesion-forming technologies for catheter ablation of atrial fibrillation. Heart Rhythm. 2007 Mar; 4(3 Suppl):S44-50. Cesario DA, Mahajan A, Shivkumar K. PMID: 17336884.
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Usefulness of preimplantation B-type natriuretic peptide level for predicting response to cardiac resynchronization therapy. Am J Cardiol. 2007 Jan 15; 99(2):242-6. Lellouche N, De Diego C, Cesario DA, Vaseghi M, Horowitz BN, Mahajan A, Wiener I, Boyle NG, Fonarow GC, Shivkumar K. PMID: 17223426.
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A novel method for preventing phrenic nerve injury during catheter ablation. Heart Rhythm. 2007 Jan; 4(1):95-8. Buch E, Vaseghi M, Cesario DA, Shivkumar K. PMID: 17198999; PMCID: PMC1794679.
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Alterations in ion channel physiology in diabetic cardiomyopathy. Endocrinol Metab Clin North Am. 2006 Sep; 35(3):601-10, ix-x. Cesario DA, Brar R, Shivkumar K. PMID: 16959588.
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Reentry around the heart. Heart Rhythm. 2007 Feb; 4(2):236-8. Vaseghi M, Shannon KM, Wetzel GT, Shivkumar K. PMID: 17275765.
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The autonomic innervation of the ligament of Marshall. J Cardiovasc Electrophysiol. 2006 Jun; 17(6):600-1. Buch E, Cesario DA, Shivkumar K. PMID: 16836705.
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Arrhythmia diagnosis: simple and elegant. Heart Rhythm. 2006 Jun; 3(6):680-1. Boyle NG, Shivkumar K. PMID: 16731469.
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Left ventricular lead stabilization utilizing a coronary stent. Pacing Clin Electrophysiol. 2006 Apr; 29(4):427-8. Cesario DA, Shenoda M, Brar R, Shivkumar K. PMID: 16650274.
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Use of thoracic epidural anesthesia for management of electrical storm: a case report. Heart Rhythm. 2005 Dec; 2(12):1359-62. Mahajan A, Moore J, Cesario DA, Shivkumar K. PMID: 16360091.
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Pulmonary-vein cryoisolation versus left-atrial linear cryoablation for atrial fibrillation. Nat Clin Pract Cardiovasc Med. 2005 Sep; 2(9):446-7. Shivkumar K. PMID: 16265583.
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Sepsis from insidious pacemaker infection and unsuspected tricuspid valve endocarditis: the importance of transesophageal echocardiography in guiding explantation strategy. J Cardiothorac Vasc Anesth. 2005 Aug; 19(4):505-7. Belikov S, Marijic J, Laks H, Staudacher M, Boyle N, Shivkumar K, Odim J. PMID: 16085259.
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Optimal combination of discriminators for differentiating ventricular from supraventricular tachycardia by dual-chamber defibrillators. J Cardiovasc Electrophysiol. 2005 Jul; 16(7):732-9. Glikson M, Swerdlow CD, Gurevitz OT, Daoud E, Shivkumar K, Wilkoff B, Shipman T, Friedman PA. PMID: 16050831.
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Counterclockwise atrial flutter in dextrocardia. Heart Rhythm. 2005 Jun; 2(6):673-4. Vaseghi M, Cesario D, Swerdlow CD, Shivkumar K. PMID: 15922281.
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Histopathologic characterization of the atrioventricular conduction axis following catheter ablation. Heart Rhythm. 2005 May; 2(5):532-5. Cesario DA, Broder HJ, Fishbein MC, Shivkumar K. PMID: 15840481.
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Incessant tachycardia following catheter ablation of an accessory pathway: what is the mechanism? Heart Rhythm. 2005 Apr; 2(4):441-2. Vaseghi M, Cesario D, Shannon KM, Shivkumar K. PMID: 15851349.
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Beyond coronary sinus angiography: the value of coronary arteriography and identification of the pericardiophrenic vein during left ventricular lead placement. Pacing Clin Electrophysiol. 2005 Mar; 28(3):185-90. Vaseghi M, Cesario DA, Ji S, Shannon KM, Wiener I, Boyle NG, Fonarow GC, Valderrábano M, Shivkumar K. PMID: 15733176.
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Transient left recurrent laryngeal nerve palsy following catheter ablation of atrial fibrillation. Heart Rhythm. 2005 Feb; 2(2):182-4. Pai RK, Boyle NG, Child JS, Shivkumar K. PMID: 15851295.
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The slippery slope of human ventricular arrhythmias. J Cardiovasc Electrophysiol. 2004 Dec; 15(12):1364-5. Shivkumar K, N Weiss J. PMID: 15610279.
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Catheter ablation of ventricular tachycardia guided by contrast-enhanced cardiac computed tomography. Heart Rhythm. 2004 Oct; 1(4):490-2. Bello D, Kipper S, Valderrábano M, Shivkumar K. PMID: 15851204.
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Percutaneous epicardial mapping during ablation of difficult accessory pathways as an alternative to cardiac surgery. Heart Rhythm. 2004 Sep; 1(3):311-6. Valderrábano M, Cesario DA, Ji S, Shannon K, Wiener I, Swerdlow CD, Oral H, Morady F, Shivkumar K. PMID: 15851176.
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The molecular basis of cardiac arrhythmias in patients with cardiomyopathy. Curr Heart Fail Rep. 2004 Sep; 1(3):98-103. Ji S, Cesario D, Valderrabano M, Shivkumar K. PMID: 16036032.
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Azygos vein lead implantation: a novel adjunctive technique for implantable cardioverter defibrillator placement. J Cardiovasc Electrophysiol. 2004 Jul; 15(7):780-3. Cesario D, Bhargava M, Valderrábano M, Fonarow GC, Wilkoff B, Shivkumar K. PMID: 15250862.
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Use of potassium channel openers for pharmacologic modulation of cardiac excitability. J Cardiovasc Electrophysiol. 2004 Jul; 15(7):821-3. Shivkumar K, Valderrabano M. PMID: 15250870.
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Electrophysiological characterization of cardiac veins in humans. J Interv Card Electrophysiol. 2004 Jun; 10(3):241-7. Cesario DA, Valderrabano M, Cai JJ, Ji S, Shannon KM, Weiss JN, Wiener I, Olshansky B, Chen PS, Shivkumar K. PMID: 15133362.
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Signal-averaged electrocardiogram in Ebstein's anomaly. Am J Cardiol. 2004 Feb 15; 93(4):432-6. Tede NH, Shivkumar K, Perloff JK, Middlekauff HR, Fishbein MC, Child JS, Laks H. PMID: 14969616.
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Left ventricular endocardial lead placement using a modified transseptal approach. J Cardiovasc Electrophysiol. 2004 Feb; 15(2):234-6. Ji S, Cesario DA, Swerdlow CD, Shivkumar K. PMID: 15028056.
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Determination of the upper limit of vulnerability using implantable cardioverter-defibrillator electrograms. Circulation. 2003 Jun 24; 107(24):3028-33. Swerdlow C, Shivkumar K, Zhang J. PMID: 12810611.
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Mechanisms of arrhythmias: are we still "learning while burning"? (editorial). J Cardiovasc Electrophysiol. 2002 Apr; 13(4):393-4. Shivkumar K. PMID: 12033358.
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The molecular basis of cardiac arrhythmias. J Nucl Cardiol. 2002 Mar-Apr; 9(2):206-14. Shivkumar K, Murali NS, Krishnan SC. PMID: 11986566.
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Unusual response to atrial extrastimulus testing. J Cardiovasc Electrophysiol. 2002 Feb; 13(2):200. Christenson SD, Olshansky B, Shivkumar K. PMID: 11900302.
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Carvedilol reduced mortality and morbidity caused by myocardial infarction in patients with left ventricular dysfunction. ACP J Club. 2002 Jan-Feb; 136(1):7. Jagasia DH, Shivkumar K. PMID: 11829548.
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