Kishore Gadde | UCI Profiles

Association of GERD with Sleeve Gastrectomy: An Unintended Consequence. Curr Diab Rep. 2026 Jan 29; 26(1):3. Talebloo J, Gadde KM, Mittal RK, Nguyen NT. PMID: 41606240; PMCID: PMC12852246.

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Sociodemographic, Clinical, and Psychosocial Predictors of Short- and Long-term Study Retention in the Diabetes Prevention Program (DPP) Outcomes Study (DPPOS). Diabetes Care. 2025 Oct 01; 48(10):1685-1694. Tjaden AH, Braffett BH, Butera NM, Araneta MR, Carmichael O, Groessl EJ, Hazuda HP, Hoskin MA, Ibebuogu U, Magee MF, Mau M, Stich T, Soliman D, Wallia A, Temprosa M, Golden SH, Diabetes Prevention Program Research Group . PMID: 40541257; PMCID: PMC12451849.

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Analysis of Long-term Follow-up of a Randomized Clinical Trial With Departures From Assigned Treatments: Estimation of Metformin Effects on Diabetes and Its Complications in the Diabetes Prevention Program Outcomes Study. Diabetes Care. 2025 Oct 01; 48(10):1668-1675. Knowler WC, Pan Q, Shu S, Tripputi MT, Dabelea D, Edelstein SL, Kahn SE, Kuo S, Luchsinger JA, Shah V, Wallia A, Temprosa M, Diabetes Prevention Program Research Group . PMID: 40857175; PMCID: PMC12451852.

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Impact of Parental or First-Degree Family History of Diabetes on Diabetes Incidence and Progression During Long-term Follow-up in the Diabetes Prevention Program Outcomes Study. Diabetes Care. 2025 Oct 01; 48(10):1695-1703. Dagogo-Jack S, Kazemi EJ, Doherty L, Srikanthan P, Echouffo-Tcheugui JB, Knowler WC, Kahn SE, Mudaliar S, Temprosa M, DPP Research Group . PMID: 40882001; PMCID: PMC12451838.

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Nonglycemic and Glycemic Risk Factors for Painful Neuropathic Symptoms and for Distal Symmetrical Polyneuropathy (DSPN) in the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study. Diabetes Care. 2025 Oct 01; 48(10):1676-1684. Herman WH, Ciarleglio A, Callaghan BC, Edelstein SL, Goldberg R, White NH, Albers JW, Diabetes Prevention Program Research Group . PMID: 40532190; PMCID: PMC12451832.

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Peripheral CB1 receptor blockade for treatment of obesity. Lancet Diabetes Endocrinol. 2025 Nov; 13(11):898-899. Gadde KM, Talebloo J, Piomelli D. PMID: 41038214.

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Association of BMI and Cognitive Performance in the Diabetes Prevention Program Outcomes Study. Obesity (Silver Spring). 2025 Dec; 33(12):2365-2376. Luchsinger JA, Pan Q, Knowler WC, Munshi M, Watson K, Gadde KM, Schlögl M, Carmichael OT, DPP Research Group. PMID: 41017217; PMCID: PMC12636062.

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Key genetic determinants of diabetes remission in patients with obesity following bariatric surgery. Updates Surg. 2025 Dec; 77(8):2579-2590. Mahjoubin-Tehran M, Talebloo J, Gadde KM, Sukhorukov VN, Jamialahmadi T, Sahebkar A. PMID: 40993333.

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The Diabetes Prevention Program and Its Outcomes Study: NIDDK's Journey Into the Prevention of Type 2 Diabetes and Its Public Health Impact. Diabetes Care. 2025 Jul 01; 48(7):1101-1111. Crandall JP, Dabelea D, Knowler WC, Nathan DM, Temprosa M, DPP Research Group . PMID: 40272279; PMCID: PMC12178622.

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Long-term changes in lipid indices following Roux-en-Y gastric bypass: a meta-analysis. Surg Endosc. 2025 Jul; 39(7):4109-4127. Jamialahamdi T, Mirhadi E, Abdalla MA, Gadde KM, Almahmeed W, Eid AH, Ahmad S, Ahmad I, Kroh M, Sahebkar A. PMID: 40325244.

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Long-term effects and effect heterogeneity of lifestyle and metformin interventions on type 2 diabetes incidence over 21 years in the US Diabetes Prevention Program randomised clinical trial. Lancet Diabetes Endocrinol. 2025 Jun; 13(6):469-481. Knowler WC, Doherty L, Edelstein SL, Bennett PH, Dabelea D, Hoskin M, Kahn SE, Kalyani RR, Kim C, Pi-Sunyer FX, Raghavan S, Shah VO, Temprosa M, Venditti EM, Nathan DM, DPP/DPPOS Research Group. PMID: 40311647; PMCID: PMC12414453.

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Flap Valve-Preserving Vertical Sleeve Gastrectomy (INNOVATE-VSG): Clinical Trial Study Protocol. Obes Surg. 2025 Mar; 35(3):1063-1069. Nguyen NT, Gadde KM, Mittal RK. PMID: 39985715; PMCID: PMC11906530.

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Beyond fat: Does semaglutide affect lean mass? Clin Nutr. 2025 Jan; 44:104-108. Jamialahmadi T, Eid AH, Gadde KM, Almahmeed W, Kroh M, Al Zein M, Sahebkar A. PMID: 39647240.

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New Generation Anti-Obesity Pharmacotherapy: Companion or Competitor to Metabolic bariatric Surgery? Drug Discov Today. 2024 Aug; 29(8):104072. Sahebkar A, Gadde KM, Kroh M, Eid AH, Jamialahmadi T. PMID: 38942072.

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Impact of bariatric surgery on circulating irisin levels: a systematic review and meta‑analysis. Updates Surg. 2024 Dec; 76(8):2745-2754. Jamialahamdi T, Mirhadi E, Almahmeed W, Eid AH, Al-Rasadi K, Nguyen NT, Gadde KM, Sahebkar A. PMID: 38743243.

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Temporal dynamics of the multi-omic response to endurance exercise training. Nature. 2024 May; 629(8010):174-183. MoTrPAC Study Group, Lead Analysts, MoTrPAC Study Group. PMID: 38693412; PMCID: PMC11062907.

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Prevalence of Distal Symmetrical Polyneuropathy by Diabetes Prevention Program Treatment Group, Diabetes Status, Duration of Diabetes, and Cumulative Glycemic Exposure. Diabetes Care. 2024 May 01; 47(5):810-817. Lee CG, Ciarleglio A, Edelstein SL, Crandall JP, Dabelea D, Goldberg RB, Kahn SE, Knowler WC, Ma MT, White NH, Herman WH, Diabetes Prevention Program Research Group . PMID: 38502874; PMCID: PMC11043227.

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Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis. Obes Surg. 2024 May; 34(5):1929-1937. Jamialahamdi T, Eid AH, Nguyen NT, Gadde KM, Sukhorukov VN, Almahmeed W, Kroh M, Sahebkar A. PMID: 38578522.

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Prevalence and predictors of female sexual dysfunction among sexually active women in the diabetes prevention program outcomes study. Neurourol Urodyn. 2024 Apr; 43(4):977-990. Gupta P, Doherty L, Temprosa M, Pop-Busui R, Gadde KM, Singh P, Owora AH, Wessells H, Sarma AV, Diabetes Prevention Program Research Group. PMID: 38501372; PMCID: PMC12285218.

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Prevalence and predictors of erectile dysfunction among men in the diabetes prevention program outcomes study. J Diabetes Complications. 2024 02; 38(2):108669. Blair YA, Doherty L, Temprosa M, Pop-Busui R, Gadde KM, Singh P, Owora AH, Wessells H, Sarma AV, Diabetes Prevention Program Research Group. PMID: 38219334; PMCID: PMC10922921.

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Improvement of Triglyceride-Glucose Index Following Bariatric Surgery: a Systematic Review and Meta-analysis. Obes Surg. 2024 Mar; 34(3):741-750. Jamialahamdi T, Gadde KM, Nguyen NT, Kroh M, Sukhorukov VN, Almahmeed W, Al-Rasadi K, Sahebkar A. PMID: 38102370.

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Effects of testosterone enanthate on aggression, risk-taking, competition, mood, and other cognitive domains during 28 days of severe energy deprivation. Psychopharmacology (Berl). 2024 Mar; 241(3):461-478. Lieberman HR, Caldwell JA, Vartanian O, Carmichael OT, Karl JP, Berryman CE, Gadde KM, Niro PJ, Harris MN, Rood JC, Pasiakos SM. PMID: 38038817; PMCID: PMC10884082.

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Coronary Artery Calcium and Cognitive Decline in the Diabetes Prevention Program Outcomes Study. J Am Heart Assoc. 2023 11 07; 12(21):e029671. Gadde KM, Yin X, Goldberg RB, Orchard TJ, Schlögl M, Dabelea D, Ibebuogu UN, Watson KE, Pi-Sunyer FX, Crandall JP, Temprosa M, Luchsinger JA, Diabetes Prevention Program Research Group. PMID: 37929764; PMCID: PMC10727391.

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Analysis of Veno-Venous Extracorporeal Membrane Oxygenation for COVID-19 Compared to Non-COVID Etiologies. Ann Surg. 2023 09 01; 278(3):464-470. Ruhi-Williams P, Wu B, Nahmias J, Sagebin F, Fazl Alizadeh R, Gadde KM, Amin A, Nguyen NT. PMID: 37325899.

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Pharmacotherapy for obesity: recent evolution and implications for cardiovascular risk reduction. Expert Rev Endocrinol Metab. 2023 Sep-Nov; 18(4):307-319. Maki KC, Kirkpatrick CF, Allison DB, Gadde KM. PMID: 37199542.

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Weight Regain After Bariatric Surgery: Scope of the Problem, Causes, Prevention, and Treatment. Curr Diab Rep. 2023 03; 23(3):31-42. Noria SF, Shelby RD, Atkins KD, Nguyen NT, Gadde KM. PMID: 36752995; PMCID: PMC9906605.

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Erratum. Effects of Cotadutide on Metabolic and Hepatic Parameters in Adults With Overweight or Obesity and Type 2 Diabetes: A 54-Week Randomized Phase 2b Study. Diabetes Care 2021;44:1433-1442. Diabetes Care. 2022 Dec 01; 45(12):3112. Nahra R, Wang T, Gadde KM, Oscarsson J, Stumvoll M, Jermutus L, Hirshberg B, Ambery P. PMID: 36228195; PMCID: PMC9763024.

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Risk of Type 2 Diabetes Among Individuals with Excess Weight: Weight Trajectory Effects. Curr Diab Rep. 2022 09; 22(9):471-479. Owora AH, Allison DB, Zhang X, Gletsu-Miller N, Gadde KM. PMID: 35781782; PMCID: PMC10094425.

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Effects of Long-term Metformin and Lifestyle Interventions on Cardiovascular Events in the Diabetes Prevention Program and Its Outcome Study. Circulation. 2022 05 31; 145(22):1632-1641. Goldberg RB, Orchard TJ, Crandall JP, Boyko EJ, Budoff M, Dabelea D, Gadde KM, Knowler WC, Lee CG, Nathan DM, Watson K, Temprosa M, Diabetes Prevention Program Research Group*. PMID: 35603600; PMCID: PMC9179081.

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The Role of Calorie Restriction in the Prevention of Cardiovascular Disease. Curr Atheroscler Rep. 2022 04; 24(4):235-242. Perry CA, Gadde KM. PMID: 35107761.

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Obesity, Body Composition, and Sex Hormones: Implications for Cardiovascular Risk. Compr Physiol. 2021 12 29; 12(1):2949-2993. Singh P, Covassin N, Marlatt K, Gadde KM, Heymsfield SB. PMID: 34964120; PMCID: PMC10068688.

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Long-acting amylin analogue for weight reduction. Lancet. 2021 12 11; 398(10317):2132-2134. Gadde KM, Allison DB. PMID: 34798059.

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Effect of Metformin and Lifestyle Interventions on Mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study. Diabetes Care. 2021 12; 44(12):2775-2782. Lee CG, Heckman-Stoddard B, Dabelea D, Gadde KM, Ehrmann D, Ford L, Prorok P, Boyko EJ, Pi-Sunyer X, Wallia A, Knowler WC, Crandall JP, Temprosa M, Diabetes Prevention Program Research Group, Diabetes Prevention Program Research Group:. PMID: 34697033; PMCID: PMC8669534.

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Targeting visceral adiposity with pharmacotherapy. Lancet Diabetes Endocrinol. 2021 09; 9(9):551-552. Gadde KM, Heymsfield SB. PMID: 34358470.

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Effects of Cotadutide on Metabolic and Hepatic Parameters in Adults With Overweight or Obesity and Type 2 Diabetes: A 54-Week Randomized Phase 2b Study. Diabetes Care. 2021 06; 44(6):1433-1442. Nahra R, Wang T, Gadde KM, Oscarsson J, Stumvoll M, Jermutus L, Hirshberg B, Ambery P. PMID: 34016612; PMCID: PMC8247525.

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Testosterone supplementation upregulates androgen receptor expression and translational capacity during severe energy deficit. Am J Physiol Endocrinol Metab. 2020 10 01; 319(4):E678-E688. Howard EE, Margolis LM, Berryman CE, Lieberman HR, Karl JP, Young AJ, Montano MA, Evans WJ, Rodriguez NR, Johannsen NM, Gadde KM, Harris MN, Rood JC, Pasiakos SM. PMID: 32776828; PMCID: PMC7750513.

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The limits and challenges of antiobesity pharmacotherapy. Expert Opin Pharmacother. 2020 Aug; 21(11):1319-1328. Gadde KM, Atkins KD. PMID: 32292094; PMCID: PMC7523877.

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Effects of Testosterone Supplementation on Ghrelin and Appetite During and After Severe Energy Deficit in Healthy Men. J Endocr Soc. 2020 Apr 01; 4(4):bvaa024. Karl JP, Berryman CE, Harris MN, Lieberman HR, Gadde KM, Rood JC, Pasiakos SM. PMID: 32258956; PMCID: PMC7101089.

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Effects of testosterone supplementation on body composition and lower-body muscle function during severe exercise- and diet-induced energy deficit: A proof-of-concept, single centre, randomised, double-blind, controlled trial. EBioMedicine. 2019 Aug; 46:411-422. Pasiakos SM, Berryman CE, Karl JP, Lieberman HR, Orr JS, Margolis LM, Caldwell JA, Young AJ, Montano MA, Evans WJ, Vartanian O, Carmichael OT, Gadde KM, Johannsen NM, Beyl RA, Harris MN, Rood JC. PMID: 31358477; PMCID: PMC6711889.

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Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study. Ann Intern Med. 2019 05 21; 170(10):682-690. Apolzan JW, Venditti EM, Edelstein SL, Knowler WC, Dabelea D, Boyko EJ, Pi-Sunyer X, Kalyani RR, Franks PW, Srikanthan P, Gadde KM, Diabetes Prevention Program Research Group. PMID: 31009939; PMCID: PMC6829283.

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Weight Loss Medications in the Treatment of Obesity and Hypertension. Curr Hypertens Rep. 2019 02 12; 21(2):16. Cohen JB, Gadde KM. PMID: 30747357; PMCID: PMC6415530.

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Relationship Between Perceptions of Obesity Causes and Weight Loss Expectations Among Adults. J Nutr Educ Behav. 2019 01; 51(1):86-90. Daigle KM, Gang CH, Kopping MF, Gadde KM. PMID: 30318272; PMCID: PMC6352733.

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Glial acetate metabolism is increased following a 72-h fast in metabolically healthy men and correlates with susceptibility to hypoglycemia. Acta Diabetol. 2018 Oct; 55(10):1029-1036. McDougal DH, Darpolor MM, DuVall MA, Sutton EF, Morrison CD, Gadde KM, Redman LM, Carmichael OT. PMID: 29931424; PMCID: PMC6153507.

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Obesity: Pathophysiology and Management. J Am Coll Cardiol. 2018 01 02; 71(1):69-84. Gadde KM, Martin CK, Berthoud HR, Heymsfield SB. PMID: 29301630; PMCID: PMC7958889.

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Pharmacotherapy for Patients with Obesity. Clin Chem. 2018 01; 64(1):118-129. Gadde KM, Apolzan JW, Berthoud HR. PMID: 29054924; PMCID: PMC7379842.

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Physiological and psychological effects of testosterone during severe energy deficit and recovery: A study protocol for a randomized, placebo-controlled trial for Optimizing Performance for Soldiers (OPS). Contemp Clin Trials. 2017 07; 58:47-57. Pasiakos SM, Berryman CE, Karl JP, Lieberman HR, Orr JS, Margolis LM, Caldwell JA, Young AJ, Montano MA, Evans WJ, Vartanian O, Carmichael OT, Gadde KM, Harris M, Rood JC. PMID: 28479217.

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Pharmacotherapy of Obesity: Clinical Trials to Clinical Practice. Curr Diab Rep. 2017 05; 17(5):34. Gadde KM, Pritham Raj Y. PMID: 28378293.

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Efficacy and safety of autoinjected exenatide once-weekly suspension versus sitagliptin or placebo with metformin in patients with type 2 diabetes: The DURATION-NEO-2 randomized clinical study. Diabetes Obes Metab. 2017 07; 19(7):979-988. Gadde KM, Vetter ML, Iqbal N, Hardy E, Öhman P, DURATION-NEO-2 study investigators. PMID: 28205322; PMCID: PMC5485171.

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Health-related quality of life in two randomized controlled trials of phentermine/topiramate for obesity: What mediates improvement? Qual Life Res. 2016 May; 25(5):1237-44. Kolotkin RL, Gadde KM, Peterson CA, Crosby RD. PMID: 26446094.

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Weight loss: slow and steady does not win the race. Lancet Diabetes Endocrinol. 2014 Dec; 2(12):927-8. Martin CK, Gadde KM. PMID: 25459210.

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Obesity medications reduce total body weight by 3-9% compared with placebo, when combined with lifestyle changes. Evid Based Nurs. 2015 Jan; 18(1):29-30. Gadde KM, Yancy WS. PMID: 24842056.

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Weight changes in obese adults 6-months after discontinuation of double-blind zonisamide or placebo treatment. Diabetes Obes Metab. 2014 Aug; 16(8):766-8. Shin JH, Gadde KM, Østbye T, Bray GA. PMID: 25123600; PMCID: PMC4135527.

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Combination phentermine/topiramate for obesity treatment in primary care: a review. Postgrad Med. 2014 Mar; 126(2):110-6. Xiong GL, Gadde KM. PMID: 24685974.

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Current pharmacotherapy for obesity: extrapolation of clinical trials data to practice. Expert Opin Pharmacother. 2014 Apr; 15(6):809-22. Gadde KM. PMID: 24548209.

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Weight loss treatment in obese adults. JAMA. 2013 Dec 18; 310(23):2568. Gadde KM. PMID: 24347000; PMCID: PMC9365294.

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Evaluation of phentermine and topiramate versus phentermine/topiramate extended-release in obese adults. Obesity (Silver Spring). 2013 Nov; 21(11):2163-71. Aronne LJ, Wadden TA, Peterson C, Winslow D, Odeh S, Gadde KM. PMID: 24136928.

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Clinical utility of phentermine/topiramate (Qsymia™) combination for the treatment of obesity. Diabetes Metab Syndr Obes. 2013; 6:131-9. Shin JH, Gadde KM. PMID: 23630428; PMCID: PMC3626409.

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Zonisamide for weight reduction in obese adults: a 1-year randomized controlled trial. Arch Intern Med. 2012 Nov 12; 172(20):1557-64. Gadde KM, Kopping MF, Wagner HR, Yonish GM, Allison DB, Bray GA. PMID: 23147455; PMCID: PMC3753218.

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Escitalopram for treatment of night eating syndrome: a 12-week, randomized, placebo-controlled trial. J Clin Psychopharmacol. 2012 Jun; 32(3):341-5. Vander Wal JS, Gang CH, Griffing GT, Gadde KM. PMID: 22544016.

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Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study. Am J Clin Nutr. 2012 Feb; 95(2):297-308. Garvey WT, Ryan DH, Look M, Gadde KM, Allison DB, Peterson CA, Schwiers M, Day WW, Bowden CH. PMID: 22158731; PMCID: PMC3260065.

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Phentermine/topiramate for weight reduction and treatment of adverse metabolic consequences in obesity. Drugs Today (Barc). 2011 Dec; 47(12):903-14. Bays HE, Gadde KM. PMID: 22348915.

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Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity (Silver Spring). 2012 Feb; 20(2):330-42. Allison DB, Gadde KM, Garvey WT, Peterson CA, Schwiers ML, Najarian T, Tam PY, Troupin B, Day WW. PMID: 22051941; PMCID: PMC3270297.

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Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial. Lancet. 2011 Apr 16; 377(9774):1341-52. Gadde KM, Allison DB, Ryan DH, Peterson CA, Troupin B, Schwiers ML, Day WW. PMID: 21481449.

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Sexual functioning in obese adults enrolling in a weight loss study. J Sex Marital Ther. 2011; 37(3):224-35. Ostbye T, Kolotkin RL, He H, Overcash F, Brouwer R, Binks M, Syrjala KL, Gadde KM. PMID: 21512941; PMCID: PMC3201733.

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Combination therapy for obesity and metabolic disease. Curr Opin Endocrinol Diabetes Obes. 2009 Oct; 16(5):353-8. Gadde KM, Allison DB. PMID: 19625958.

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Missing data in randomized clinical trials for weight loss: scope of the problem, state of the field, and performance of statistical methods. PLoS One. 2009 Aug 13; 4(8):e6624. Elobeid MA, Padilla MA, McVie T, Thomas O, Brock DW, Musser B, Lu K, Coffey CS, Desmond RA, St-Onge MP, Gadde KM, Heymsfield SB, Allison DB. PMID: 19675667; PMCID: PMC2720539.

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Sample size in obesity trials: patient perspective versus current practice. Med Decis Making. 2010 Jan-Feb; 30(1):68-75. Allison DB, Elobeid MA, Cope MB, Brock DW, Faith MS, Vander Veur S, Berkowitz R, Cutter G, McVie T, Gadde KM, Foster GD. PMID: 19675318; PMCID: PMC2914621.

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The effect of acute tryptophan depletion on emotional distraction and subsequent memory. Soc Cogn Affect Neurosci. 2009 Dec; 4(4):357-68. Wang L, Mullette-Gillman OA, Gadde KM, Kuhn CM, McCarthy G, Huettel SA. PMID: 19628700; PMCID: PMC2799951.

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Combination pharmaceutical therapies for obesity. Expert Opin Pharmacother. 2009 Apr; 10(6):921-5. Gadde KM, Allison DB. PMID: 19351275; PMCID: PMC4780673.

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Rational design of a combination medication for the treatment of obesity. Obesity (Silver Spring). 2009 Jan; 17(1):30-9. Greenway FL, Whitehouse MJ, Guttadauria M, Anderson JW, Atkinson RL, Fujioka K, Gadde KM, Gupta AK, O'Neil P, Schumacher D, Smith D, Dunayevich E, Tollefson GD, Weber E, Cowley MA. PMID: 18997675.

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118
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Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats. Neuropsychopharmacology. 2008 Nov; 33(12):2922-33. Wallingford NM, Sinnayah P, Bymaster FP, Gadde KM, Krishnan RK, McKinney AA, Landbloom RP, Tollefson GD, Cowley MA. PMID: 18322467.

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10
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Animals Cells
Childhood socioeconomic status and serotonin transporter gene polymorphism enhance cardiovascular reactivity to mental stress. Psychosom Med. 2008 01; 70(1):32-9. Williams RB, Marchuk DA, Siegler IC, Barefoot JC, Helms MJ, Brummett BH, Surwit RS, Lane JD, Kuhn CM, Gadde KM, Ashley-Koch A, Svenson IK, Suarez EC, Schanberg SM. PMID: 18158371.

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21
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Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study. J Clin Psychiatry. 2007 Aug; 68(8):1226-9. Gadde KM, Yonish GM, Foust MS, Wagner HR. PMID: 17854247.

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21
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A randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of topiramate controlled release in the treatment of obese type 2 diabetic patients. Diabetes Care. 2007 Jun; 30(6):1480-6. Rosenstock J, Hollander P, Gadde KM, Sun X, Strauss R, Leung A, OBD-202 Study Group. PMID: 17363756.

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20
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Escitalopram treatment of trichotillomania. Int Clin Psychopharmacol. 2007 Jan; 22(1):39-42. Gadde KM, Ryan Wagner H, Connor KM, Foust MS. PMID: 17159458.

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4
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Humans CTClinical Trials
Bupropion for weight reduction. Expert Rev Neurother. 2007 Jan; 7(1):17-24. Gadde KM, Xiong GL. PMID: 17187492.

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13
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Cannabinoid-1 receptor antagonist, rimonabant, for management of obesity and related risks. Circulation. 2006 Aug 29; 114(9):974-84. Gadde KM, Allison DB. PMID: 16940206.

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23
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Effect of rimonabant on weight and cardiometabolic risk factors. JAMA. 2006 Aug 09; 296(6):649-50; author reply 650-1. Gadde KM. PMID: 16896103.

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2
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Modafinil for atypical depression: effects of open-label and double-blind discontinuation treatment. J Clin Psychopharmacol. 2006 Aug; 26(4):373-8. Vaishnavi S, Gadde K, Alamy S, Zhang W, Connor K, Davidson JR. PMID: 16855454.

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6
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Bupropion treatment of olanzapine-associated weight gain: an open-label, prospective trial. J Clin Psychopharmacol. 2006 Aug; 26(4):409-13. Gadde KM, Zhang W, Foust MS. PMID: 16855461.

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   Mentions:
5
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Humans CTClinical Trials
Atomoxetine for weight reduction in obese women: a preliminary randomised controlled trial. Int J Obes (Lond). 2006 Jul; 30(7):1138-42. Gadde KM, Yonish GM, Wagner HR, Foust MS, Allison DB. PMID: 16418753.

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12
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Endocannabinoid receptor antagonists and other emerging pharma-cological strategies for weight reduction. Curr Drug Targets Cardiovasc Haematol Disord. 2005 Dec; 5(6):549-56. Gadde KM. PMID: 16503875.

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1
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Hyperforin plasma level as a marker of treatment adherence in the National Institutes of Health Hypericum Depression Trial. J Clin Psychopharmacol. 2005 Jun; 25(3):243-9. Vitiello B, Shader RI, Parker CB, Ritz L, Harlan W, Greenblatt DJ, Gadde KM, Krishnan KR, Davidson JR. PMID: 15876903.

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   Mentions:
7
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Humans Animals CTClinical Trials
The use of aripiprazole in obsessive-compulsive disorder: preliminary observations in 8 patients. J Clin Psychiatry. 2005 Jan; 66(1):49-51. Connor KM, Payne VM, Gadde KM, Zhang W, Davidson JR. PMID: 15669888.

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33
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Humans CTClinical Trials
Fluoxetine, comprehensive cognitive behavioral therapy, and placebo in generalized social phobia. Arch Gen Psychiatry. 2004 Oct; 61(10):1005-13. Davidson JR, Foa EB, Huppert JD, Keefe FJ, Franklin ME, Compton JS, Zhao N, Connor KM, Lynch TR, Gadde KM. PMID: 15466674.

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91
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Assessing patient beliefs in a clinical trial of Hypericum perforatum in major depression. Depress Anxiety. 2004; 20(3):114-22. Bann CM, Parker CB, Bradwejn J, Davidson JR, Vitiello B, Gadde KM. PMID: 15549690.

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10
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Zonisamide for weight loss in obese adults: a randomized controlled trial. JAMA. 2003 Apr 09; 289(14):1820-5. Gadde KM, Franciscy DM, Wagner HR, Krishnan KR. PMID: 12684361.

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49
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Bupropion SR vs. placebo for weight loss in obese patients with depressive symptoms. Obes Res. 2002 Oct; 10(10):1049-56. Jain AK, Kaplan RA, Gadde KM, Wadden TA, Allison DB, Brewer ER, Leadbetter RA, Richard N, Haight B, Jamerson BD, Buaron KS, Metz A. PMID: 12376586.

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38
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Serotonin-related gene polymorphisms and central nervous system serotonin function. Neuropsychopharmacology. 2003 Mar; 28(3):533-41. Williams RB, Marchuk DA, Gadde KM, Barefoot JC, Grichnik K, Helms MJ, Kuhn CM, Lewis JG, Schanberg SM, Stafford-Smith M, Suarez EC, Clary GL, Svenson IK, Siegler IC. PMID: 12629534.

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91
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Bupropion SR enhances weight loss: a 48-week double-blind, placebo- controlled trial. Obes Res. 2002 Jul; 10(7):633-41. Anderson JW, Greenway FL, Fujioka K, Gadde KM, McKenney J, O'Neil PM. PMID: 12105285.

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69
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Effect of Hypericum perforatum (St John's wort) in major depressive disorder: a randomized controlled trial. JAMA. 2002 04 10; 287(14):1807-14. Hypericum Depression Trial Study Group, Davidson JR, Gadde KM, Fairbank JA, Krishnan KRR, Califf RM, Binanay C, Parker CB, Pugh N, Hartwell TD, Vitiello B, Ritz L, Severe J, Cole JO, de Battista C, Doraiswamy PM, Feighner JP, Keck P, Kelsey J, Lin KM, Londborg PD, Nemeroff CB, Schatzberg AF, Sheehan DV, Srivastava RK, Taylor L, Trivedi MH, Weisler RH. PMID: 11939866.

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76
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Bupropion for weight loss: an investigation of efficacy and tolerability in overweight and obese women. Obes Res. 2001 Sep; 9(9):544-51. Gadde KM, Parker CB, Maner LG, Wagner HR, Logue EJ, Drezner MK, Krishnan KR. PMID: 11557835.

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35
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Central nervous system serotonin function and cardiovascular responses to stress. Psychosom Med. 2001 Mar-Apr; 63(2):300-5. Williams RB, Marchuk DA, Gadde KM, Barefoot JC, Grichnik K, Helms MJ, Kuhn CM, Lewis JG, Schanberg SM, Stafford-Smith M, Suarez EC, Clary GL, Svenson IK, Siegler IC. PMID: 11292279.

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   Mentions:
34
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Humans Cells CTClinical Trials
Psychoneuroendocrinology and brain imaging in depression. Psychiatr Clin North Am. 1998 Jun; 21(2):465-72. Krishnan KR, Gadde KM, Kim YD. PMID: 9670237.

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Diltiazem effect on carbamazepine levels in manic depression. J Clin Psychopharmacol. 1990 Oct; 10(5):378-9. Gadde K, Calabrese JR. PMID: 2258457.

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1
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Humans