Michael Bailey
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Contact Information
Call us at:
(614) 722-2764
Fax us at:
(614) 722-2817
Email Michael Bailey, PhD
Center for Microbe and Immunity Research
Abigail Wexner Research Institute
700 Children’s Dr., W410
Columbus, OH 43205
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Learn more about Michael Bailey
Research
Lab(s)
Center for Microbe and Immunity Research
Bailey Lab
View My Publications
Publications
Spencer KD, Bline H, Chen HJ, Verosky BG, Hilt ME, Jaggers RM, Gur TL, Mathé EA, Bailey MT. Modulation of anxiety-like behavior in galactooligosaccharide-fed mice: A potential role for bacterial tryptophan metabolites and reduced microglial reactivity.
Brain Behav Immun.
2024 Jul 25;
Caetano-Silva ME, Shrestha A, Duff AF, Kontic D, Brewster PC, Kasperek MC, Lin CH, Wainwright DA, Hernandez-Saavedra D, Woods JA, Bailey MT, Buford TW, Allen JM. Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation.
Aging Cell.
2024 May 9; e14190.
Duff AF, Jurcisek JA, Kurbatfinski N, Chiang T, Goodman SD, Bakaletz LO, Bailey MT. Oral and middle ear delivery of otitis media standard of care antibiotics, but not biofilm-targeted antibodies, alter chinchilla nasopharyngeal and fecal microbiomes.
NPJ Biofilms Microbiomes.
2024 Feb 3; 10: 10.
Madison AA, Bailey MT. Stressed to the Core: Inflammation and Intestinal Permeability Link Stress-Related Gut Microbiota Shifts to Mental Health Outcomes.
Biol Psychiatry.
2024 Feb 15; 95: 339-347.
Maltz RM, Marte-Ortiz P, McClinchie MG, Hilt ME, Bailey MT. T Cell-Induced Colitis Is Exacerbated by Prolonged Stress: A Comparison in Male and Female Mice.
Biomedicines.
2024 Jan 18; 12:
Loman BR, Alzoubi Z, Lynch AJ, Jaggers RM, Jordan K, Grant CV, Rogers LK, Pyter LM, Bailey MT. Paclitaxel chemotherapy disrupts microbiota-enterohepatic bile acid metabolism in mice.
Gut Microbes.
2024 Jan-Dec; 16: 2410475.
Hussan H, Clinton SK, Grainger EM, Webb M, Wang C, Webb A, Needleman B, Noria S, Zhu J, Choueiry F, Pietrzak M, Bailey MT. Distinctive patterns of sulfide- and butyrate-metabolizing bacteria after bariatric surgery: potential implications for colorectal cancer risk.
Gut Microbes.
2023 Dec; 15: 2255345.
Chen HJ, Galley JD, Verosky BG, Yang FA, Rajasekera TA, Bailey MT, Gur TL. Fetal CCL2 signaling mediates offspring social behavior and recapitulates effects of prenatal stress.
Brain Behav Immun.
2023 Oct 30;
Ragan MV, Wala SJ, Sajankila N, Duff AF, Wang Y, Volpe SG, Al-Hadidi A, Dumbauld Z, Purayil N, Wickham J, Conces MR, Mihi B, Goodman SD, Bailey MT, Besner GE. Development of a novel definitive scoring system for an enteral feed-only model of necrotizing enterocolitis in piglets.
Front Pediatr.
2023; 11: 1126552.
Khalsa AS, Burton J, Bailey MT, Zhu J, Kelleher KJ, Maltz RM, Loman BR, Spees CK. Collection of biospecimens from parent-child dyads in a community garden-based nutrition intervention: protocol and feasibility.
BMC Nutr.
2022 Dec 5; 8: 141.
Chen HJ, Bischoff A, Galley JD, Peck L, Bailey MT, Gur TL. Discrete role for maternal stress and gut microbes in shaping maternal and offspring immunity.
Neurobiol Stress.
2022 Nov; 21: 100480.
Loman BR, Russart KLG, Grant CV, Lynch AJ, Bailey MT, Pyter LM. Mammary tumors alter the fecal bacteriome and permit enteric bacterial translocation.
BMC Cancer.
2022 Mar 5; 22: 245.
Maltz RM, Marte-Ortiz P, Rajasekera TA, Loman BR, Gur TL, Bailey MT. Stressor-Induced Increases in Circulating, but Not Colonic, Cytokines Are Related to Anxiety-like Behavior and Hippocampal Inflammation in a Murine Colitis Model.
Int J Mol Sci.
2022 Feb 11; 23:
Allen JM, Mackos AR, Jaggers RM, Brewster PC, Webb M, Lin CH, Ladaika C, Davies R, White P, Loman BR, Bailey MT. Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes.
Gut Microbes.
2022 Jan-Dec; 14: 2035661.
Jaggers RM, DiSabato DJ, Loman BR, Kontic D, Spencer KD, Allen JM, Godbout JP, Quan N, Gur TL, Bailey MT. Stressor-Induced Reduction in Cognitive Behavior is Associated with Impaired Colonic Mucus Layer Integrity and is Dependent Upon the LPS-Binding Protein Receptor CD14.
J Inflamm Res.
2022; 15: 1617-1635.
Ragan MV, Wala SJ, Goodman SD, Bailey MT, Besner GE. Next-Generation Probiotic Therapy to Protect the Intestines From Injury.
Front Cell Infect Microbiol.
2022; 12: 863949.
Hill EB, Chen L, Bailey MT, Singh Khalsa A, Maltz R, Kelleher K, Spees CK, Zhu J, Loman BR. Facilitating a high-quality dietary pattern induces shared microbial responses linking diet quality, blood pressure, and microbial sterol metabolism in caregiver-child dyads.
Gut Microbes.
2022 Jan-Dec; 14: 2150502.
Salman SS, Williams KC, Marte-Ortiz P, Rumpf W, Mashburn-Warren L, Lauber CL, Bailey MT, Maltz RM. Polyethylene Glycol 3350 Changes Stool Consistency and the Microbiome but not Behavior of CD1 Mice.
J Pediatr Gastroenterol Nutr.
2021 Oct 1; 73: 499-506.
Shelby RD, Mar P, Janzow GE, Mashburn-Warren L, Tengberg N, Navarro JB, Allen JM, Wickham J, Wang Y, Bailey MT, Goodman SD, Besner GE. Antibacterial and anti-inflammatory effects of Lactobacillus reuteri in its biofilm state contribute to its beneficial effects in a rat model of experimental necrotizing enterocolitis.
J Pediatr Surg.
2021 Sep 20;
Wang Y, Jaggers RM, Mar P, Galley JD, Shaffer T, Rajab A, Deshpande S, Mashburn-Warren L, Buzzo JR, Goodman SD, Bailey MT, Besner GE.
Lactobacillus reuteri
in its biofilm state promotes neurodevelopment after experimental necrotizing enterocolitis in rats.
Brain Behav Immun Health.
2021 Jul; 14:
Amato KR, Arrieta MC, Azad MB, Bailey MT, Broussard JL, Bruggeling CE, Claud EC, Costello EK, Davenport ER, Dutilh BE, Swain Ewald HA, Ewald P, Hanlon EC, Julion W, Keshavarzian A, Maurice CF, Miller GE, Preidis GA, Segurel L, Singer B, Subramanian S, Zhao L, Kuzawa CW. The human gut microbiome and health inequities.
Proc Natl Acad Sci U S A.
2021 Jun 22; 118:
Eichler T, Bender K, Murtha MJ, Schwartz L, Metheny J, Solden L, Jaggers RM, Bailey MT, Gupta S, Mosquera C, Ching C, La Perle K, Li B, Becknell B, Spencer JD. Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.
J Am Soc Nephrol.
2019 Aug; 30: 1385-1397.
Dettmer AM, Allen JM, Jaggers RM, Bailey MT. A descriptive analysis of gut microbiota composition in differentially reared infant rhesus monkeys (Macaca mulatta) across the first 6 months of life.
Am J Primatol.
2019 Apr 2; e22969.
Gu J, Thomas-Ahner JM, Riedl KM, Bailey MT, Vodovotz Y, Schwartz SJ, Clinton SK. Dietary Black Raspberries Impact the Colonic Microbiome and Phytochemical Metabolites in Mice.
Mol Nutr Food Res.
2019 Apr; 63: e1800636.
Maltz RM, Keirsey J, Kim SC, Mackos AR, Gharaibeh RZ, Moore CC, Xu J, Somogyi A, Bailey MT. Social Stress Affects Colonic Inflammation, the Gut Microbiome, and Short-chain Fatty Acid Levels and Receptors.
J Pediatr Gastroenterol Nutr.
2019 Apr; 68: 533-540.
Shelby RD, Tengberg N, Conces M, Olson JK, Navarro JB, Bailey MT, Goodman SD, Besner GE. Development of a Standardized Scoring System to Assess a Murine Model of Clostridium difficile Colitis.
J Invest Surg.
2019 Mar 20; 1-9.
Gur TL, Palkar AV, Rajasekera T, Allen J, Niraula A, Godbout J, Bailey MT. Prenatal stress disrupts social behavior, cortical neurobiology and commensal microbes in adult male offspring.
Behav Brain Res.
2019 Feb 1; 359: 886-894.
Allen JM, Jaggers RM, Solden LM, Loman BR, Davies RH, Mackos AR, Ladaika CA, Berg BM, Chichlowski M, Bailey MT. Dietary Oligosaccharides Attenuate Stress-Induced Disruptions in Immune Reactivity and Microbial B-Vitamin Metabolism.
Front Immunol.
2019; 10: 1774.
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Biography
Michael Bailey, PhD, is a principal investigator in the Center for Microbe and Immunity Research at the Abigail Wexner Research Institute at Nationwide Children’s Hospital and is an associate professor of Pediatrics at The Ohio State University. Dr. Bailey has nearly 20 years of experience studying bidirectional interactions between host physiology and the microbes that naturally reside within the gastrointestinal tract (i.e., the gut microbiota). Dr. Bailey’s studies were among the first to show that stressful situations can lead to changes in the composition of the gut microbiota and his current studies are now focused on the impact that changes to gut microbiota composition have on the functioning of the immune system and on nervous system activity.
Academic and Clinical Areas
Center for Microbe and Immunity Research
Principal Investigator
Bailey Lab
Principal Investigator
Primary Department
Center for Microbe and Immunity Research
Awards, Honors & Organizations
Robert Ader New Investigator Award, PsychoNeuroImmunology Research Society, 2012
Education
Doctorate
University of Wisconsin
Date Completed:
01/01/2002
Graduate School
Minnesota State University, Mankato
Date Completed:
01/01/1997
Undergraduate School
Winona State University
Date Completed:
01/01/1995
Professional Experience
2015 - Present
The Ohio State University College of Medicine, Associate Professor of Pediatrics
Contact Information
Center for Microbe and Immunity Research
Call us at:
(614) 722-2764
Fax us at:
(614) 722-2817
Email Michael Bailey
Abigail Wexner Research Institute
700 Children’s Dr., W410
Columbus, OH 43205
map