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Urinary Tobacco and Nicotine Exposure Biomarkers as Predictors of Transitions between Cigarette and e-Cigarette Use in the Exhale Longitudinal Cohort Study. Nicotine Tob Res. 2026 Feb 24; 28(3):446-453. Brouwer AF, Shafie-Khorassani F, Benowitz N, Shi N, Baker TB, Hayes-Birchler T, Piper ME. PMID: 40832891; PMCID: PMC12409742.
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Sustained effects of reduced nicotine cigarettes and co-use of non-combusted alternative nicotine delivery systems: A one-month follow-up to a randomized clinical trial. Drug Alcohol Depend. 2026 Feb 01; 279:113051. Klemperer EM, Luo X, Cao Q, Carroll DM, McClernon FJ, Benowitz NL, Strasser AA, Tidey JW, Donny EC, Hatsukami DK. PMID: 41570485.
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California's New Landmark Thirdhand Smoke Disclosure Law. JAMA. 2025 Dec 23; 334(24):2157-2158. Matt GE, Benowitz NL. PMID: 41264305.
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Thirdhand smoke disclosure in real estate: California adopts novel tobacco control and prevention legislation. Tob Control. 2025 Dec 10. Matt GE, Benowitz NL, California Collaborative Consortium on Thirdhand Smoke. PMID: 41371934.
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The Impact of Nicotine Reduction on Cigarette Reinforcement Value Within a Marketplace Containing Alternative Nicotine Delivery Products: A Secondary Analysis of a Multi-Site Trial. Nicotine Tob Res. 2025 Nov 23; 27(12):2240-2246. Smith TT, Luo X, Benowitz NL, Colby SM, McClernon FJ, Strasser AA, Tidey JW, Donny EC, Hatsukami DK. PMID: 40613327; PMCID: PMC13010486.
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Theoretical and retrograde calculation of blood alcohol: wide estimates using the Academy Standards Board for calculations over an extended period of time. Lab Med. 2025 Nov 22; 56(6):829-831. Wu AHB, Benowitz N. PMID: 40973110; PMCID: PMC12639538.
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Susceptibility to E-Cigarette and Cigarette Use Among U.S. Adolescents. J Adolesc Health. 2026 Feb; 78(2):332-340. Zhang J, Benowitz NL, Dai HD. PMID: 41269181.
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Assessing the Urinary Cyanoethyl Mercapturic Acid to Cotinine Ratio for Classifying Tobacco Use Status in a Longitudinal Cohort of Cigarette, e-Cigarette, and Dual Users. Nicotine Tob Res. 2025 Oct 24. Nieto A, Zhang C, Zhu W, Reese C, Piper ME, Benowitz NL, Blount BC, Bhandari D. PMID: 41134288.
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Differences in Combustible Cigarette Smoking-Related Biomarkers by Hormonal Contraceptive Use: An Exploratory Study. Nicotine Tob Res. 2025 Oct 22; 27(11):2022-2027. Allen AM, Cao Q, Stayer LG, Luo X, Jensen J, Pang RD, Allen S, Donny EC, Benowitz N, Smith T, Hatsukami D. PMID: 39883066.
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E-Cigarettes in Historical Context-Innovation, Risk, and Regulation. JAMA Health Forum. 2025 Oct 03; 6(10):e254629. Pesko MF, Hartmann-Boyce J, Fung RYL, Benowitz NL. PMID: 41105414; PMCID: PMC12924721.
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Corrigendum to Reduced nicotine in cigarettes in a marketplace with alternative nicotine systems: randomized clinical trial. Lancet Reg Health Am. 2025 Nov; 51:101244. Hatsukami DK, Jensen JA, Carroll DM, Luo X, Strayer LG, Cao Q, Hecht SS, Murphy SE, Carmella SG, Denlinger-Apte RL, Colby S, Strasser AA, McClernon FJ, Tidey J, Benowitz NL, Donny EC. PMID: 41080612; PMCID: PMC12510229.
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Continuous Nicotine Monitors for Personal Nicotine Pharmacokinetics: A Receptor-Aware Research Agenda. Nicotine Tob Res. 2025 Aug 22; 27(9):1499-1512. Nichols AL, Marotta CB, Lukas H, Friesenhahn NJ, Wagenaar DA, Mayo SL, Dougherty DA, Benowitz NL, Gao W, Muthusamy AK, Lester HA. PMID: 40079271; PMCID: PMC12370474.
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Caffeine, nicotine, cannabis, and psilocybin: Pharmacology, toxicology, and potential therapeutic uses of four naturally occurring psychoactive substances. Swiss Med Wkly. 2025 07 01; 155:4346. Christen SE, Bekka E, Schmid Y, Benowitz NL, Liakoni E. PMID: 40811135.
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Cytisinicline for Smoking Cessation: The ORCA Phase 3 Replication Randomized Clinical Trial. JAMA Intern Med. 2025 Jun 01; 185(6):648-655. Rigotti NA, Benowitz NL, Prochaska JJ, Rubinstein M, Clarke A, Blumenstein B, Cain DF, Jacobs C. PMID: 40257755; PMCID: PMC12012700.
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Canadian Cardiovascular Society Clinical Practice Update on Contemporary Approaches to Smoking Cessation. Can J Cardiol. 2025 May; 41(5):797-812. Mir H, Eisenberg MJ, Benowitz NL, Cowley E, Heshmati J, Jha P, Khara M, Mullen KA, Ofori SN, Rigotti NA, San Cartier R. PMID: 40340054.
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Using a loose-leaf vaporizer to study tobacco-cannabis co-administration: A proof-of-concept study. Drug Alcohol Depend. 2025 Jul 01; 272:112678. St Helen G, Havel C, Addo N, Criner N, Jacob P, Benowitz N. PMID: 40328077.
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Predicting Cardiovascular Risk With Use of Various Tobacco Products. Circulation. 2025 Apr 08; 151(14):1006-1008. Benowitz NL. PMID: 40193542.
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Nicotine Dosimetry in Evaluating Electronic Cigarettes Compared to Cigarette Smoking: Implications for Tobacco Regulatory Science. Chem Res Toxicol. 2025 Apr 21; 38(4):686-694. Benowitz NL, Yang HY, Jacob P, St Helen G. PMID: 40094483; PMCID: PMC12015950.
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Nicotine levels in flavoured hookah (waterpipe) tobacco products: discrepancies between labelled and measured levels. Tob Control. 2025 Jan 11. Rezk-Hanna M, Ben Taleb Z, Benowitz NL. PMID: 39798996.
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Impact of Smokeless Oral Nicotine Products on Cardiovascular Disease: Implications for Policy, Prevention, and Treatment: A Policy Statement From the American Heart Association. Circulation. 2025 Jan 07; 151(1):e1-e21. Dennison Himmelfarb CR, Benowitz NL, Blank MD, Bhatnagar A, Chase PJ, Davis EM, Fetterman JL, Keller-Hamilton B, Ogungbe O, Page RL, Rezk-Hanna M, Robertson RM, Whitsel LP, American Heart Association Advocacy Coordinating Committee. PMID: 39624904.
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Tobacco Biomarkers by Latino Heritage and Race, US, 2007 to 2014 National Health and Nutrition Examination Survey. Cancer Epidemiol Biomarkers Prev. 2024 Dec 02; 33(12):1586-1597. Duong C, Rodriquez EJ, Hinerman AS, Hooshmand S, Claudel SE, Benowitz NL, Pérez-Stable EJ. PMID: 39348098; PMCID: PMC11611627.
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E-cigarettes, synthetic nicotine, heated-tobacco and smokeless nicotine delivery products: the nicotine landscape beyond combustible cigarettes. Swiss Med Wkly. 2024 11 04; 154:3583. Liakoni E, Christen SE, Benowitz NL. PMID: 39835719.
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Cytisinicline For E-Cigarette Cessation-Reply. JAMA Intern Med. 2024 Nov 01; 184(11):1393-1394. Rigotti NA, Benowitz NL, Jacobs C. PMID: 39250151.
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Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants. Tob Control. 2024 10 19; 33(6):798-806. Matt GE, Greiner L, Record RA, Wipfli H, Long J, Dodder NG, Hoh E, Lopez Galvez N, Novotny TE, Quintana PJE, Destaillats H, Tang X, Snijders AM, Mao JH, Hang B, Schick S, Jacob P, Talbot P, Mahabee-Gittens EM, Merianos AL, Northrup TF, Gundel L, Benowitz NL. PMID: 37263783; PMCID: PMC11503167.
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A randomized controlled trial evaluation of a smoking cessation and physical activity intervention delivered via telemedicine in the Norton Sound region of Alaska. Addict Behav. 2025 Jan; 160:108179. Prochaska JJ, Vogel EA, Oppezzo M, Skan J, Knox M, Chieng A, Crouch MC, Aikens RC, Schnellbaecher M, Benowitz NL. PMID: 39348775; PMCID: PMC11560622.
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Pharmacokinetics and Pharmacodynamics of Inhaled Nicotine Salt and Free-Base Using an E-cigarette: A Randomized Crossover Study. Nicotine Tob Res. 2024 Sep 23; 26(10):1313-1321. Christen SE, Hermann L, Bekka E, Vonwyl C, Hammann F, van der Velpen V, Eap CB, Benowitz NL, Haschke M, Liakoni E. PMID: 38597729; PMCID: PMC11417154.
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Cytisinicline for Vaping Cessation in Adults Using Nicotine E-Cigarettes: The ORCA-V1 Randomized Clinical Trial. JAMA Intern Med. 2024 08 01; 184(8):922-930. Rigotti NA, Benowitz NL, Prochaska JJ, Cain DF, Ball J, Clarke A, Blumenstein BA, Jacobs C. PMID: 38709500; PMCID: PMC11074928.
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Reduced nicotine in cigarettes in a marketplace with alternative nicotine systems: randomized clinical trial. Lancet Reg Health Am. 2024 Jul; 35:100796. Hatsukami DK, Jensen JA, Carroll DM, Luo X, Strayer LG, Cao Q, Hecht SS, Murphy SE, Carmella SG, Denlinger-Apte RL, Colby S, Strasser AA, McClernon FJ, Tidey J, Benowitz NL, Donny EC. PMID: 38911348; PMCID: PMC11190722.
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Nicotine Delivery and Changes in Withdrawal and Craving During Acute Electronic Cigarette, Heated Tobacco Product, and Cigarette Use Among a Sample of Black and White People Who Smoke. Nicotine Tob Res. 2024 May 22; 26(6):780-784. Leavens ELS, Lambart L, Diaz FJ, Wagener TL, Ahluwalia JS, Benowitz N, Nollen NL. PMID: 38097340; PMCID: PMC11109490.
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Menthol versus tobacco e-liquid flavor: Impact on acute subjective effects, puff patterns, and intentions for use among Black and White menthol smokers. Addict Behav. 2024 08; 155:108038. Leavens ELS, Lambart LM, St Helen G, Benowitz NL, Mayo MS, Farhad Mahmud KM, Arnold MJ, Nollen NL. PMID: 38613857; PMCID: PMC11221762.
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Tobacco Constituents, Flavorants, and Paper Permeability of Factory-Made and Roll-Your-Own Cigarettes on the Australian Market. Nicotine Tob Res. 2024 02 22; 26(3):289-297. Haynes A, Winnall WR, Brennan E, Dunstone K, Benowitz NL, Ashley DL, Samet JM, Hatsukami DK, Wakefield MA. PMID: 37462724.
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Society for Research on Nicotine and Tobacco as an Outgrowth of the 1988 Surgeon General's Report on Nicotine Addiction: Reflections of the Early Presidents. Nicotine Tob Res. 2024 01 22; 26(2):118-125. Pomerleau OF, Benowitz NL, Stitzer ML, Henningfield JE, Hatsukami DK, Corrigall WA, Perkins KA, Lando HA. PMID: 37584666; PMCID: PMC10803119.
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Electronic hookah (waterpipe) vaping reduces vascular endothelial function: the role of nicotine. Am J Physiol Heart Circ Physiol. 2024 03 01; 326(3):H490-H496. Rezk-Hanna M, Rossman MJ, Ludwig K, Sakti P, Cheng CW, Brecht ML, Benowitz NL, Seals DR. PMID: 38133618; PMCID: PMC11219048.
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Associations of Cannabis Use, High-Risk Alcohol Use, and Depressive Symptomology with Motivation and Attempts to Quit Cigarette Smoking Among Adults: Findings from the 2020 ITC Four Country Smoking and Vaping Survey. Int J Ment Health Addict. 2025; 23(3):2021-2045. Gravely S, Driezen P, Shahab L, McClure EA, Hyland A, Cummings KM, East KA, Chan GCK, Walsh H, Benowitz NL, Gartner CE, Fong GT, Quah ACK, Smith DM. PMID: 40703248; PMCID: PMC12279565.
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Association of non-daily hookah tobacco smoking and cardiovascular disease-related exposure biomarkers among U.S. users: The Population Assessment of Tobacco and Health Study. Prev Med Rep. 2023 Dec; 36:102417. Rezk-Hanna M, Adolfo A, Warda US, Brecht ML, Benowitz NL. PMID: 37753385; PMCID: PMC10518337.
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Biomarkers of Toxic Exposure and Oxidative Stress Among U.S. Adult Users of Premium Cigar Versus Other Cigar Subtypes: 2013-2019. Nicotine Tob Res. 2023 07 28; 25(Suppl_1):S84-S93. Dai HD, Benowitz NL, Rogan E, Degarege A, Buckley J, Khan AS. PMID: 37506235; PMCID: PMC10381103.
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Nicotine Intake in Adult Pod E-cigarette Users: Impact of User and Device Characteristics. Nicotine Tob Res. 2023 07 14; 25(8):1489-1495. Giberson J, Nardone N, Addo N, Khan S, Jacob P, Benowitz N, St Helen G. PMID: 37061820; PMCID: PMC10347964.
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Cytisinicline for Smoking Cessation: A Randomized Clinical Trial. JAMA. 2023 07 11; 330(2):152-160. Rigotti NA, Benowitz NL, Prochaska J, Leischow S, Nides M, Blumenstein B, Clarke A, Cain D, Jacobs C. PMID: 37432430; PMCID: PMC10336611.
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How the FDA Can Improve Public Health - Helping People Stop Smoking. N Engl J Med. 2023 04 27; 388(17):1540-1542. Benowitz NL, Warner KE, Myers ML, Hatsukami D, Berman ML, Vallone D, Cohen JE. PMID: 37092791.
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Smoking cessation, harm reduction, and biomarkers protocols in the PhenX Toolkit: Tools for standardized data collection. Addict Neurosci. 2023 Sep; 7. Bierut LJ, Hendershot TP, Benowitz NL, Cummings KM, Mermelstein RJ, Piper ME, Vrieze SI, Wagener TL, Nelms MD, Ives C, Maiese D, Hamilton CM, Swan GE. PMID: 38645895; PMCID: PMC11027214.
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A Phase I, Double-blind, Randomized, Placebo-controlled, Single Dose-escalation Study to Evaluate the Tolerability, and Safety of Cytisinicline in Adult Smokers. Nicotine Tob Res. 2023 03 22; 25(4):814-820. Jacobs C, Fonseca M, Rigotti NA, Benowitz N, Clarke A, Cain D. PMID: 36198104.
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Thirdhand tobacco smoke exposure increases the genetic background-dependent risk of pan-tumor development in Collaborative Cross mice. Environ Int. 2023 04; 174:107876. Yang H, Wang X, Wang P, He L, Schick SF, Jacob P, Benowitz N, Gundel LA, Zhu C, Xia Y, Inman JL, Chang H, Snijders AM, Mao JH, Hang B. PMID: 36940581; PMCID: PMC11439420.
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Nicotine e-cigarettes as a tool for smoking cessation. Nat Med. 2023 03; 29(3):520-524. Warner KE, Benowitz NL, McNeill A, Rigotti NA. PMID: 36788367.
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A critique of the Australian National Health and Medical Research Council CEO statement on electronic cigarettes. Addiction. 2023 06; 118(6):1184-1192. Mendelsohn CP, Hall W, Borland R, Wodak A, Beaglehole R, Benowitz NL, Britton J, Bullen C, Etter JF, McNeill A, Rigotti NA. PMID: 36808672.
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Associations of Demographics, Dependence, and Biomarkers With Transitions in Tobacco Product Use in a Cohort of Cigarette Users and Dual Users of Cigarettes and E-cigarettes. Nicotine Tob Res. 2023 02 09; 25(3):462-469. Shafie-Khorassani F, Piper ME, Jorenby DE, Baker TB, Benowitz NL, Hayes-Birchler T, Meza R, Brouwer AF. PMID: 36037523; PMCID: PMC9910158.
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The E-cigarette or Vaping Product Use-Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2023 01; 20(1):1-17. Rebuli ME, Rose JJ, Noël A, Croft DP, Benowitz NL, Cohen AH, Goniewicz ML, Larsen BT, Leigh N, McGraw MD, Melzer AC, Penn AL, Rahman I, Upson D, Crotty Alexander LE, Ewart G, Jaspers I, Jordt SE, Kligerman S, Loughlin CE, McConnell R, Neptune ER, Nguyen TB, Pinkerton KE, Witek TJ. PMID: 36584985; PMCID: PMC9819258.
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Vaping THC-O Acetate: Potential for Another EVALI Epidemic. J Med Toxicol. 2023 01; 19(1):37-39. Benowitz NL, Havel C, Jacob P, O'Shea DF, Wu D, Fowles J. PMID: 36508081; PMCID: PMC9813278.
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Caffeine levels and dietary intake in smokers with schizophrenia and bipolar disorder. Psychiatry Res. 2023 01; 319:114989. Rosen RL, Ramasubramani RS, Benowitz NL, Gandhi KK, Williams JM. PMID: 36470161; PMCID: PMC11385874.
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Lifetime use of non-nicotine drugs in electronic cigarette devices among a sample of individuals in substance use disorder treatment. Addict Behav Rep. 2022 Dec; 16:100465. Masson CL, Gubner NR, Benowitz N, Hosakote S, Le T, Guydish JR. PMID: 36341309; PMCID: PMC9633988.
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Early Changes in Puffing Intensity When Exclusively Using Open-Label Very Low Nicotine Content Cigarettes. Nicotine Tob Res. 2022 10 26; 24(11):1798-1802. White CM, Watson C, Bravo Cardenas R, Ngac P, Valentin-Blasini L, Blount BC, Koopmeiners JS, Denlinger-Apte RL, Pacek LR, Benowitz NL, Hatsukami DK, Donny EC, Carpenter MJ, Smith TT. PMID: 35524988; PMCID: PMC9597006.
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Association of cannabis use during pregnancy with severe acute respiratory syndrome coronavirus 2 infection: a retrospective cohort study. Addiction. 2023 02; 118(2):317-326. Young-Wolff KC, Ray GT, Alexeeff SE, Benowitz N, Adams SR, Does MB, Goler N, Ansley D, Conway A, Avalos LA. PMID: 36189777; PMCID: PMC9812868.
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Demographic and cultural correlates of traditional eating among Alaska Native adults at risk for cardiovascular disease. PLoS One. 2022; 17(9):e0275445. Sanders MA, Oppezzo M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. PMID: 36178914; PMCID: PMC9524684.
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The Effect of Tobacco Use on the Expression of Placental Transporters in Alaska Native Women. Clin Pharmacol Ther. 2023 03; 113(3):634-642. McColl ER, Kwok J, Benowitz NL, Patten CA, Hughes CA, Koller KR, Flanagan CA, Thomas TK, Hiratsuka VY, Tyndale RF, Piquette-Miller M. PMID: 36053152; PMCID: PMC10234256.
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Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current understanding and recommendations for future research. Lancet Respir Med. 2022 09; 10(9):900-915. Benowitz NL, Goniewicz ML, Halpern-Felsher B, Krishnan-Sarin S, Ling PM, O'Connor RJ, Pentz MA, Robertson RM, Bhatnagar A. PMID: 35985357; PMCID: PMC9381032.
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Traditional Heart-Healthy Diet and Medication Adherence in the Norton Sound Region: An 18-Month Telehealth Intervention. Int J Environ Res Public Health. 2022 08 11; 19(16). Oppezzo M, Knox M, Skan J, Chieng A, Crouch M, Aikens RC, Benowitz NL, Schnellbaecher M, Prochaska JJ. PMID: 36011519; PMCID: PMC9408057.
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Thirdhand Exposures to Tobacco-Specific Nitrosamines through Inhalation, Dust Ingestion, Dermal Uptake, and Epidermal Chemistry. Environ Sci Technol. 2022 09 06; 56(17):12506-12516. Tang X, Benowitz N, Gundel L, Hang B, Havel CM, Hoh E, Jacob Iii P, Mao JH, Martins-Green M, Matt GE, Quintana PJE, Russell ML, Sarker A, Schick SF, Snijders AM, Destaillats H. PMID: 35900278; PMCID: PMC11439435.
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Smoking abstinence and cessation-related outcomes one month after an immediate versus gradual reduction in nicotine content of cigarettes. Prev Med. 2022 12; 165(Pt B):107175. Klemperer EM, Luo X, Jensen J, al'Absi M, Cinciripini PM, Robinson JD, Drobes DJ, McClernon J, Strasser AA, Strayer LG, Vandrey R, Benowitz NL, Donny EC, Hatsukami DK. PMID: 35870575; PMCID: PMC10676511.
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Associations of Smokeless Tobacco Use With Cardiovascular Disease Risk: Insights From the Population Assessment of Tobacco and Health Study. Nicotine Tob Res. 2022 06 15; 24(7):1063-1070. Rezk-Hanna M, Warda US, Stokes AC, Fetterman J, Li J, Macey PM, Darawad M, Song Y, Ben Taleb Z, Brecht ML, Benowitz NL. PMID: 34999825; PMCID: PMC9199939.
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Effects of Marijuana Use on Smokers Switching to E-Cigarettes in a Randomized Clinical Trial. Nicotine Tob Res. 2022 06 15; 24(7):994-1002. Rice M, Nollen NL, Ahluwalia JS, Benowitz N, Woodcock A, Pulvers K. PMID: 35022796; PMCID: PMC9199934.
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Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers: The Kick It at Swope IV Randomized Clinical Trial. JAMA. 2022 06 14; 327(22):2201-2209. Cox LS, Nollen NL, Mayo MS, Faseru B, Greiner A, Ellerbeck EF, Krebill R, Tyndale RF, Benowitz NL, Ahluwalia JS. PMID: 35699705; PMCID: PMC9198729.
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Minor Tobacco Alkaloids as Biomarkers to Distinguish Combusted Tobacco Use From Electronic Nicotine Delivery Systems Use. Two New Analytical Methods. Front Chem. 2022; 10:749089. Jacob P, Chan L, Cheung P, Bello K, Yu L, StHelen G, Benowitz NL. PMID: 35720984; PMCID: PMC9198481.
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Cigarette Smoke Exposure and Acute Respiratory Distress Syndrome in Sepsis: Epidemiology, Clinical Features, and Biologic Markers. Am J Respir Crit Care Med. 2022 04 15; 205(8):927-935. Moazed F, Hendrickson C, Jauregui A, Gotts J, Conroy A, Delucchi K, Zhuo H, Arambulo M, Vessel K, Ke S, Deiss T, Ni A, Leligdowicz A, Abbott J, Cohen MJ, Sinha P, Gomez A, Kangelaris K, Kornblith L, Matthay M, Benowitz N, Liu K, Calfee CS. PMID: 35050845; PMCID: PMC9838633.
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The Central Role of pH in the Clinical Pharmacology of Nicotine: Implications for Abuse Liability, Cigarette Harm Reduction and FDA Regulation. Clin Pharmacol Ther. 2022 05; 111(5):1004-1006. Benowitz NL. PMID: 35220591; PMCID: PMC9035094.
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Tobacco-specific and combustion pollutants in settled house dust in Malta. J Environ Expo Assess. 2022; 1. Aquilina NJ, Havel CM, Benowitz NL, Jacob P. PMID: 35497707; PMCID: PMC9056077.
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Maternal nicotine metabolism moderates the impact of maternal cigarette smoking on infant birth weight: A Collaborative Perinatal Project investigation. Drug Alcohol Depend. 2022 04 01; 233:109358. Stroud LR, Papandonatos GD, Jao NC, Niaura R, Buka S, Benowitz NL. PMID: 35247723; PMCID: PMC8977115.
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Exposure to Toxicants Associated With Use and Transitions Between Cigarettes, e-Cigarettes, and No Tobacco. JAMA Netw Open. 2022 02 01; 5(2):e2147891. Dai H, Benowitz NL, Achutan C, Farazi PA, Degarege A, Khan AS. PMID: 35142830; PMCID: PMC8832174.
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Balfour et al. Respond. Am J Public Health. 2022 01; 112(1):e5-e6. Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. PMID: 34936414; PMCID: PMC8713597.
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Balfour et al. Respond. Am J Public Health. 2022 01; 112(1):e2-e3. Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. PMID: 34936419; PMCID: PMC8713616.
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Reappraising Choice in Addiction: Novel Conceptualizations and Treatments for Tobacco Use Disorder. Nicotine Tob Res. 2022 01 01; 24(1):3-9. Palmer AM, Toll BA, Carpenter MJ, Donny EC, Hatsukami DK, Rojewski AM, Smith TT, Sofuoglu M, Thrul J, Benowitz NL. PMID: 34270729; PMCID: PMC8666123.
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Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion-aided smoking cessation in African Americans? A moderated mediation analysis. Addiction. 2022 06; 117(6):1715-1724. Chenoweth MJ, Peng AR, Zhu AZX, Cox LS, Nollen NL, Ahluwalia JS, Benowitz NL, Knight J, Swardfager W, Tyndale RF. PMID: 34791718.
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Secondhand smoke exposure in school children in Malta assessed through urinary biomarkers. Environ Res. 2022 03; 204(Pt D):112405. Aquilina NJ, Jacob P, Benowitz NL, Fsadni P, Montefort S. PMID: 34822856; PMCID: PMC9119146.
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Determination of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK) arising from tobacco smoke in airborne particulate matter. Environ Int. 2022 01; 158:106992. Aquilina NJ, Havel CM, Harrison RM, Ho KF, Benowitz NL, Jacob Iii P. PMID: 34991253; PMCID: PMC9056076.
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Tobacco use disorder and cardiovascular health. Addiction. 2022 04; 117(4):1128-1138. Benowitz NL, Liakoni E. PMID: 34590373.
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Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans. Sci Rep. 2021 10 01; 11(1):19572. Chenoweth MJ, Cox LS, Nollen NL, Ahluwalia JS, Benowitz NL, Lerman C, Knight J, Tyndale RF. PMID: 34599228; PMCID: PMC8486765.
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Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes. Clin Transl Sci. 2022 01; 15(1):204-220. El-Boraie A, Tanner JA, Zhu AZX, Claw KG, Prasad B, Schuetz EG, Thummel KE, Fukunaga K, Mushiroda T, Kubo M, Benowitz NL, Lerman C, Tyndale RF. PMID: 34476898; PMCID: PMC8742641.
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A Multicenter, Double-Blind, Randomized, Placebo-Controlled Phase 2b Trial of Cytisinicline in Adult Smokers (The ORCA-1 Trial). Nicotine Tob Res. 2021 08 29; 23(10):1656-1663. Nides M, Rigotti NA, Benowitz N, Clarke A, Jacobs C. PMID: 33847362; PMCID: PMC8403245.
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Balancing Consideration of the Risks and Benefits of E-Cigarettes. Am J Public Health. 2021 09; 111(9):1661-1672. Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. PMID: 34410826; PMCID: PMC8589069.
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Clinical Pharmacology of Electronic Nicotine Delivery Systems (ENDS): Implications for Benefits and Risks in the Promotion of the Combusted Tobacco Endgame. J Clin Pharmacol. 2021 08; 61 Suppl 2:S18-S36. Benowitz NL, St Helen G, Liakoni E. PMID: 34396553; PMCID: PMC9239851.
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Effect of race and glucuronidation rates on the relationship between nicotine metabolite ratio and nicotine clearance. Pharmacogenet Genomics. 2021 07 01; 31(5):97-107. Liakoni E, Tyndale RF, Jacob P, Dempsey DA, Addo N, Benowitz NL. PMID: 33675323; PMCID: PMC8184575.
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A mixed effects model for analyzing area under the curve of longitudinally measured biomarkers with missing data. Pharm Stat. 2021 11; 20(6):1249-1264. Shi L, Hatsukami DK, Koopmeiners JS, Le CT, Benowitz NL, Donny EC, Luo X. PMID: 34151513; PMCID: PMC8604790.
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3-Ethenylpyridine Measured in Urine of Active and Passive Smokers: A Promising Biomarker and Toxicological Implications. Chem Res Toxicol. 2021 06 21; 34(6):1630-1639. Liu J, Benowitz NL, Hatsukami DK, Havel CM, Lazcano-Ponce E, Strasser AA, Jacob P. PMID: 33998799; PMCID: PMC8217284.
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Estimation of risk of neuropsychiatric adverse events from varenicline, bupropion and nicotine patch versus placebo: secondary analysis of results from the EAGLES trial using Bayes factors. Addiction. 2021 10; 116(10):2816-2824. Beard E, Jackson SE, Anthenelli RM, Benowitz NL, Aubin LS, McRae T, Lawrence D, Russ C, Krishen A, Evins AE, West R. PMID: 33885203; PMCID: PMC8612131.
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Nicotine metabolite ratio: Comparison of the three urinary versions to the plasma version and nicotine clearance in three clinical studies. Drug Alcohol Depend. 2021 06 01; 223:108708. Giratallah HK, Chenoweth MJ, Addo N, Ahluwalia JS, Cox LS, Lerman C, George TP, Benowitz NL, Tyndale RF. PMID: 33873029; PMCID: PMC8133391.
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Thirdhand smoke associations with the gut microbiomes of infants admitted to a neonatal intensive care unit: An observational study. Environ Res. 2021 06; 197:111180. Northrup TF, Stotts AL, Suchting R, Matt GE, Quintana PJE, Khan AM, Green C, Klawans MR, Johnson M, Benowitz N, Jacob P, Hoh E, Hovell MF, Stewart CJ. PMID: 33865820; PMCID: PMC8187318.
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Correlates of the nicotine metabolite ratio in Alaska Native people who smoke cigarettes. Exp Clin Psychopharmacol. 2022 Jun; 30(3):359-364. Vogel EA, Benowitz NL, Skan J, Schnellbaecher M, Prochaska JJ. PMID: 33856821; PMCID: PMC8517031.
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Nicotine delivery and cigarette equivalents from vaping a JUULpod. Tob Control. 2022 08; 31(e1):e88-e93. Prochaska JJ, Vogel EA, Benowitz N. PMID: 33762429; PMCID: PMC8460696.
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Ascorbic Acid Prevents Vascular Endothelial Dysfunction Induced by Electronic Hookah (Waterpipe) Vaping. J Am Heart Assoc. 2021 02; 10(5):e019271. Rezk-Hanna M, Seals DR, Rossman MJ, Gupta R, Nettle CO, Means A, Dobrin D, Cheng CW, Brecht ML, Mosenifar Z, Araujo JA, Benowitz NL. PMID: 33615833; PMCID: PMC8174254.
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E-Cigarettes and Cardiopulmonary Health. Function (Oxf). 2021; 2(2):zqab004. Tarran R, Barr RG, Benowitz NL, Bhatnagar A, Chu HW, Dalton P, Doerschuk CM, Drummond MB, Gold DR, Goniewicz ML, Gross ER, Hansel NN, Hopke PK, Kloner RA, Mikheev VB, Neczypor EW, Pinkerton KE, Postow L, Rahman I, Samet JM, Salathe M, Stoney CM, Tsao PS, Widome R, Xia T, Xiao D, Wold LE. PMID: 33748758; PMCID: PMC7948134.
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Ubiquitous atmospheric contamination by tobacco smoke: Nicotine and a new marker for tobacco smoke-derived particulate matter, nicotelline. Environ Int. 2021 05; 150:106417. Aquilina NJ, Havel CM, Cheung P, Harrison RM, Ho KF, Benowitz NL, Jacob Iii P. PMID: 33561671; PMCID: PMC7987222.
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Assessment of Racial Differences in Pharmacotherapy Efficacy for Smoking Cessation: Secondary Analysis of the EAGLES Randomized Clinical Trial. JAMA Netw Open. 2021 01 04; 4(1):e2032053. Nollen NL, Ahluwalia JS, Sanderson Cox L, Okuyemi K, Lawrence D, Samuels L, Benowitz NL. PMID: 33464316; PMCID: PMC7816102.
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Transferability of Ancestry-Specific and Cross-Ancestry CYP2A6 Activity Genetic Risk Scores in African and European Populations. Clin Pharmacol Ther. 2021 10; 110(4):975-985. El-Boraie A, Chenoweth MJ, Pouget JG, Benowitz NL, Fukunaga K, Mushiroda T, Kubo M, Nollen NL, Sanderson Cox L, Lerman C, Knight J, Tyndale RF. PMID: 33300144; PMCID: PMC8187466.
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"I actually finally feel like the cigarettes aren't controlling me." - Interviews with participants smoking very low nicotine content cigarettes during a residential study. Drug Alcohol Depend. 2021 02 01; 219:108465. Denlinger-Apte RL, White CM, Donny EC, Hatsukami DK, Benowitz NL, Carpenter MJ, Smith TT. PMID: 33383351; PMCID: PMC7855643.
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Recruitment best practices of a cardiovascular risk reduction randomised control trial in rural Alaska Native communities. Int J Circumpolar Health. 2020 Dec; 79(1):1806639. Knox M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. PMID: 32787541; PMCID: PMC7480599.
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Twenty-Four-Hour Cardiovascular Effects of Electronic Cigarettes Compared With Cigarette Smoking in Dual Users. J Am Heart Assoc. 2020 12; 9(23):e017317. Benowitz NL, St Helen G, Nardone N, Addo N, Zhang JJ, Harvanko AM, Calfee CS, Jacob P. PMID: 33208019; PMCID: PMC7763797.
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Efficacy and Safety of Pharmacotherapeutic Smoking Cessation Aids in Schizophrenia Spectrum Disorders: Subgroup Analysis of EAGLES. Psychiatr Serv. 2021 01 01; 72(1):7-15. Evins AE, West R, Benowitz NL, Russ C, Lawrence D, McRae T, Maravic MC, Heffner JL, Anthenelli RM. PMID: 33138708; PMCID: PMC10228639.
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Effect of Pod e-Cigarettes vs Cigarettes on Carcinogen Exposure Among African American and Latinx Smokers: A Randomized Clinical Trial. JAMA Netw Open. 2020 11 02; 3(11):e2026324. Pulvers K, Nollen NL, Rice M, Schmid CH, Qu K, Benowitz NL, Ahluwalia JS. PMID: 33206193; PMCID: PMC7675102.
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Relationships Between Race, Gender, and Spot Urine Levels of Biomarkers of Tobacco Exposure Vary Based on How Creatinine Is Handled in Analyses. Nicotine Tob Res. 2020 10 29; 22(11):2109-2113. Carroll DM, Cigan S, Ikuemonisan J, Hammonds T, Stepanov I, St Helen G, Benowitz N, Hatsukami DK. PMID: 32598452; PMCID: PMC7593361.
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Australian smokers' experiences and perceptions of recessed and firm filter cigarettes. Tob Control. 2021 11; 30(6):660-667. Wakefield MA, Dunstone K, Brennan E, Vittiglia A, Scollo M, Durkin SJ, Hoek J, Thrasher J, Hatsukami D, Benowitz N, Samet JM. PMID: 33115960.
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Exposure to a Tobacco-Specific Carcinogen Among Adolescent Smokeless Tobacco Users in Rural California, United States. Nicotine Tob Res. 2020 10 08; 22(10):1764-1771. Chaffee BW, Jacob P, Couch ET, Benowitz NL. PMID: 31504879; PMCID: PMC7542655.
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Corrigendum to: Changes in Use Patterns Over 1 Year Among Smokers and Dual Users of Combustible and Electronic Cigarettes. Nicotine Tob Res. 2020 10 08; 22(10):1934. Piper ME, Baker TB, Benowitz NL, Jorenby DE. PMID: 31609417; PMCID: PMC7542636.
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Relations among cigarette dependence, e-cigarette dependence, and key dependence criteria among dual users of combustible and e-cigarettes. Psychol Addict Behav. 2022 Feb; 36(1):100-108. Piper ME, Baker TB, Mermelstein R, Benowitz N, Jorenby DE. PMID: 32955271; PMCID: PMC7981280.
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Comprehensive Parent-Metabolite PBPK/PD Modeling Insights into Nicotine Replacement Therapy Strategies. Clin Pharmacokinet. 2020 09; 59(9):1119-1134. Kovar L, Selzer D, Britz H, Benowitz N, St Helen G, Kohl Y, Bals R, Lehr T. PMID: 32166575; PMCID: PMC7467963.
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A Mobile Health Intervention for Adolescents Exposed to Secondhand Smoke: Pilot Feasibility and Efficacy Study. JMIR Form Res. 2020 Aug 19; 4(8):e18583. Nardone N, Giberson J, Prochaska JJ, Jain S, Benowitz NL. PMID: 32812888; PMCID: PMC7468632.
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Effects of Nicotine Metabolic Rate on Cigarette Reinforcement. Nicotine Tob Res. 2020 07 16; 22(8):1419-1423. Liakoni E, Nardone N, St Helen G, Dempsey DA, Tyndale RF, Benowitz NL. PMID: 31725872; PMCID: PMC7364822.
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Analysis of Multiple Biomarkers Using Structural Equation Modeling. Tob Regul Sci. 2020 Jul; 6(4):266-278. Cao W, Hecht SS, Murphy SE, Chu H, Benowitz NL, Donny EC, Hatsukami DK, Luo X. PMID: 35530662; PMCID: PMC9075702.
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Cultural and demographic correlates of dual tobacco use in a sample of Alaska Native adults who smoke cigarettes. Tob Induc Dis. 2020; 18:55. Epperson AE, Crouch M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. PMID: 32587486; PMCID: PMC7309271.
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Biomarkers of Exposure for Dual Use of Electronic Cigarettes and Combustible Cigarettes: Nicotelline, NNAL, and Total Nicotine Equivalents. Nicotine Tob Res. 2020 06 12; 22(7):1107-1113. Jacob P, St Helen G, Yu L, Nardone N, Havel C, Cheung P, Benowitz NL. PMID: 31833541; PMCID: PMC7291810.
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Characterization of Nicotine Salts in 23 Electronic Cigarette Refill Liquids. Nicotine Tob Res. 2020 06 12; 22(7):1239-1243. Harvanko AM, Havel CM, Jacob P, Benowitz NL. PMID: 31821492; PMCID: PMC7291795.
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Development and Piloting Testing of an Experimental Tobacco and Nicotine Product Marketplace. Nicotine Tob Res. 2020 06 12; 22(7):1230-1234. Carroll DM, Strayer L, Nardone N, Pacek LR, Kozink RV, Tessier K, McClernon J, Benowitz N, Bickel WK, Hatsukami D. PMID: 31603515; PMCID: PMC7291811.
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Biochemical Verification of Tobacco Use and Abstinence: 2019 Update. Nicotine Tob Res. 2020 06 12; 22(7):1086-1097. Benowitz NL, Bernert JT, Foulds J, Hecht SS, Jacob P, Jarvis MJ, Joseph A, Oncken C, Piper ME. PMID: 31570931; PMCID: PMC7882145.
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Changes in Use Patterns Over 1 Year Among Smokers and Dual Users of Combustible and Electronic Cigarettes. Nicotine Tob Res. 2020 04 21; 22(5):672-680. Piper ME, Baker TB, Benowitz NL, Jorenby DE. PMID: 31058284; PMCID: PMC7457322.
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E-cigarette Dependence Measures in Dual Users: Reliability and Relations With Dependence Criteria and E-cigarette Cessation. Nicotine Tob Res. 2020 04 21; 22(5):756-763. Piper ME, Baker TB, Benowitz NL, Smith SS, Jorenby DE. PMID: 30874804; PMCID: PMC7368344.
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Evaluation of nicotine patch adherence measurement using self-report and saliva cotinine among abstainers in a smoking cessation trial. Drug Alcohol Depend. 2020 05 01; 210:107967. Schnoll R, Paul Wileyto E, Gross R, Hitsman B, Hawk LW, Cinciripini P, George TP, Benowitz NL, Fen Lubitz S, Ashare R, Tyndale RF, Lerman C. PMID: 32224420; PMCID: PMC7190433.
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Peripheral Blood Flow Changes to Cutaneous and Muscular Beds in Response to Acute Hookah Smoking. Am J Cardiol. 2020 06 01; 125(11):1725-1731. Rezk-Hanna M, Nelson MD, Rader F, Benowitz NL, Rosenberry R, Chang LC, Li N, Tashkin DP, Elashoff RM, Victor RG. PMID: 32278465.
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Comparison of smoking cessation rates of Quitline users in Korea between smokers of ultra-low nicotine yield cigarettes and other types of cigarette: a prospective study. Addiction. 2020 09; 115(9):1745-1753. Park EY, Park E, Jeong BY, Park J, Lee DH, Benowitz NL, Lim MK. PMID: 32083364; PMCID: PMC7522678.
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Mouth-Level Nicotine Intake Estimates from Discarded Filter Butts to Examine Compensatory Smoking in Low Nicotine Cigarettes. Cancer Epidemiol Biomarkers Prev. 2020 03; 29(3):643-649. Smith TT, Koopmeiners JS, Hatsukami DK, Tessier KM, Benowitz NL, Murphy SE, Strasser AA, Tidey JW, Blount BC, Valentin L, Bravo Cardenas R, Watson C, Pirkle JL, Donny EC. PMID: 32102909; PMCID: PMC7100998.
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The Impact of Exclusive Use of Very Low Nicotine Cigarettes on Compensatory Smoking: An Inpatient Crossover Clinical Trial. Cancer Epidemiol Biomarkers Prev. 2020 04; 29(4):880-886. Smith TT, Koopmeiners JS, White CM, Denlinger-Apte RL, Pacek LR, De Jesús VR, Wang L, Watson C, Blount BC, Hatsukami DK, Benowitz NL, Donny EC, Carpenter MJ. PMID: 32102910; PMCID: PMC7125007.
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Relationships between the Nicotine Metabolite Ratio and a Panel of Exposure and Effect Biomarkers: Findings from Two Studies of U.S. Commercial Cigarette Smokers. Cancer Epidemiol Biomarkers Prev. 2020 04; 29(4):871-879. Carroll DM, Murphy SE, Benowitz NL, Strasser AA, Kotlyar M, Hecht SS, Carmella SG, McClernon FJ, Pacek LR, Dermody SS, Vandrey RG, Donny EC, Hatsukami DK. PMID: 32051195; PMCID: PMC7437528.
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Twenty-four-hour subjective and pharmacological effects of ad-libitum electronic and combustible cigarette use among dual users. Addiction. 2020 06; 115(6):1149-1159. Harvanko AM, St Helen G, Nardone N, Addo N, Benowitz NL. PMID: 31837232; PMCID: PMC7255919.
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Urine Metabolites for Estimating Daily Intake of Nicotine From Cigarette Smoking. Nicotine Tob Res. 2020 02 06; 22(2):288-292. Benowitz NL, St Helen G, Nardone N, Cox LS, Jacob P. PMID: 30852610; PMCID: PMC7297087.
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Differences in nicotine intake and effects from electronic and combustible cigarettes among dual users. Addiction. 2020 04; 115(4):757-767. St Helen G, Nardone N, Addo N, Dempsey D, Havel C, Jacob P, Benowitz NL. PMID: 31691397; PMCID: PMC7339816.
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Seizures After Vaping Nicotine in Youth: A Canary or a Red Herring? J Adolesc Health. 2020 01; 66(1):1-2. Benowitz NL. PMID: 31866053.
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Effects of Very Low Nicotine Content Cigarettes on Smoking Behavior and Biomarkers of Exposure in Menthol and Non-menthol Smokers. Nicotine Tob Res. 2019 12 23; 21(Suppl 1):S63-S72. Denlinger-Apte RL, Kotlyar M, Koopmeiners JS, Tidey JW, Luo X, Benowitz NL, Jensen JA, Ikuemonisan JO, Pacek LR, Smith TT, Vandrey R, Donny EC, Hatsukami DK. PMID: 31867637; PMCID: PMC6939781.
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The Role of Compensation in Nicotine Reduction. Nicotine Tob Res. 2019 12 23; 21(Suppl 1):S16-S18. Benowitz NL, Donny EC, Edwards KC, Hatsukami D, Smith TT. PMID: 31867654; PMCID: PMC6939759.
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Sources and Biomarkers of Secondhand Tobacco Smoke Exposure in Urban Adolescents. Acad Pediatr. 2020 May - Jun; 20(4):493-500. Nardone N, Jain S, Addo N, St Helen G, Jacob P, Benowitz NL. PMID: 31866460; PMCID: PMC7967984.
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The influence of nicotine metabolic rate on working memory over 6 hours of abstinence from nicotine. Pharmacol Biochem Behav. 2020 01; 188:172836. Nardone N, Shahid M, Strasser AA, Dempsey DA, Benowitz NL. PMID: 31812759; PMCID: PMC7009742.
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Effect of e-cigarette flavors on nicotine delivery and puffing topography: results from a randomized clinical trial of daily smokers. Psychopharmacology (Berl). 2020 Feb; 237(2):491-502. Voos N, Smith D, Kaiser L, Mahoney MC, Bradizza CM, Kozlowski LT, Benowitz NL, O'Connor RJ, Goniewicz ML. PMID: 31773209; PMCID: PMC7691130.
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Impact of early nausea on varenicline adherence and smoking cessation. Addiction. 2020 01; 115(1):134-144. Peng AR, Swardfager W, Benowitz NL, Ahluwalia JS, Lerman C, Nollen NL, Tyndale RF. PMID: 31502736; PMCID: PMC6933078.
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Current advances in research in treatment and recovery: Nicotine addiction. Sci Adv. 2019 10; 5(10):eaay9763. Prochaska JJ, Benowitz NL. PMID: 31663029; PMCID: PMC6795520.
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Factors That Explain Differences in Abstinence Between Black and White Smokers: A Prospective Intervention Study. J Natl Cancer Inst. 2019 10 01; 111(10):1078-1087. Nollen NL, Mayo MS, Sanderson Cox L, Benowitz NL, Tyndale RF, Ellerbeck EF, Scheuermann TS, Ahluwalia JS. PMID: 30657926; PMCID: PMC6792072.
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E-Hookah Versus E-Cigarettes: Findings From Wave 2 of the PATH Study (2014-2015). Am J Prev Med. 2019 11; 57(5):e163-e173. Rezk-Hanna M, Toyama J, Ikharo E, Brecht ML, Benowitz NL. PMID: 31564602.
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Comparison of Systemic Exposure to Toxic and/or Carcinogenic Volatile Organic Compounds (VOC) during Vaping, Smoking, and Abstention. Cancer Prev Res (Phila). 2020 02; 13(2):153-162. St Helen G, Liakoni E, Nardone N, Addo N, Jacob P, Benowitz NL. PMID: 31554628; PMCID: PMC7007368.
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Quantitative biochemical screening for marijuana use and concordance with tobacco use in urban adolescents. Drug Alcohol Depend. 2019 12 01; 205:107583. Benowitz N, Nardone N, St Helen G, Addo N, Jacob P, Liakoni E, Jain S, Hooshfar S, Lynch K. PMID: 31600618; PMCID: PMC6893148.
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E-cigarettes and dual nicotine replacement therapy for smoking cessation. Lancet Respir Med. 2020 01; 8(1):7-8. Benowitz NL. PMID: 31515174.
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Reductions in urinary metabolites of exposure to household air pollution in pregnant, rural Guatemalan women provided liquefied petroleum gas stoves. J Expo Sci Environ Epidemiol. 2020 03; 30(2):362-373. Weinstein JR, Diaz-Artiga A, Benowitz N, Thompson LM. PMID: 31477781; PMCID: PMC7044065.
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Relationship between skin melanin index and nicotine pharmacokinetics in African American smokers. Drug Alcohol Depend. 2019 11 01; 204:107474. Liakoni E, St Helen G, Dempsey DA, Jacob P, Tyndale RF, Benowitz NL. PMID: 31521954; PMCID: PMC7272190.
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Dual Users Compared to Smokers: Demographics, Dependence, and Biomarkers. Nicotine Tob Res. 2019 08 19; 21(9):1279-1284. Piper ME, Baker TB, Benowitz NL, Kobinsky KH, Jorenby DE. PMID: 30365010; PMCID: PMC7182769.
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Cardiovascular Effects of Hookah Smoking: Potential Implications for Cardiovascular Risk. Nicotine Tob Res. 2019 08 19; 21(9):1151-1161. Rezk-Hanna M, Benowitz NL. PMID: 29660041.
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Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers. J Expo Sci Environ Epidemiol. 2021 03; 31(2):211-223. St Helen G, Benowitz NL, Ko J, Jacob P, Gregorich SE, Pérez-Stable EJ, Murphy SE, Hecht SS, Hatsukami DK, Donny EC. PMID: 31406274; PMCID: PMC7012700.
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JUUL electronic cigarettes: Nicotine exposure and the user experience. Drug Alcohol Depend. 2019 10 01; 203:83-87. Nardone N, Helen GS, Addo N, Meighan S, Benowitz NL. PMID: 31408770; PMCID: PMC7339945.
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Cytisine for nicotine addiction treatment: a review of pharmacology, therapeutics and an update of clinical trial evidence for smoking cessation. Addiction. 2019 11; 114(11):1951-1969. Tutka P, Vinnikov D, Courtney RJ, Benowitz NL. PMID: 31240783.
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Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects. Addiction. 2019 10; 114(10):1824-1833. Hatsukami DK, Luo X, Heskin AK, Tang MK, Carmella SG, Jensen J, Robinson JD, Vandrey R, Drobes DJ, Strasser AA, al'Absi M, Leischow S, Cinciripini PM, Koopmeiners J, Ikuemonisan J, Benowitz NL, Donny EC, Hecht SS. PMID: 31140663; PMCID: PMC6732016.
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Black Light Smokers: How Nicotine Intake and Carcinogen Exposure Differ Across Various Biobehavioral Factors. J Natl Med Assoc. 2019 Oct; 111(5):509-520. St Helen G, Benowitz NL, Ahluwalia JS, Tyndale RF, Addo N, Gregorich SE, Pérez-Stable EJ, Cox LS. PMID: 31084916; PMCID: PMC6842416.
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High Carbon Monoxide Levels from Charcoal Combustion Mask Acute Endothelial Dysfunction Induced by Hookah (Waterpipe) Smoking in Young Adults. Circulation. 2019 05 07; 139(19):2215-2224. Rezk-Hanna M, Mosenifar Z, Benowitz NL, Rader F, Rashid M, Davoren K, Moy NB, Doering L, Robbins W, Sarna L, Li N, Chang LC, Elashoff RM, Victor RG. PMID: 30764644.
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Randomized within-subject trial to evaluate smokers' initial perceptions, subjective effects and nicotine delivery across six vaporized nicotine products. Addiction. 2019 07; 114(7):1236-1248. Voos N, Kaiser L, Mahoney MC, Bradizza CM, Kozlowski LT, Benowitz NL, O'Connor RJ, Goniewicz ML. PMID: 30851137; PMCID: PMC6646880.
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Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation. PLoS One. 2019; 14(4):e0215853. Carmella SG, Heskin AK, Tang MK, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami DK, Hecht SS. PMID: 31022220; PMCID: PMC6483352.
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Predictors of Neuropsychiatric Adverse Events with Smoking Cessation Medications in the Randomized Controlled EAGLES Trial. J Gen Intern Med. 2019 06; 34(6):862-870. Anthenelli RM, Gaffney M, Benowitz NL, West R, McRae T, Russ C, Lawrence D, St Aubin L, Krishen A, Evins AE. PMID: 30847828; PMCID: PMC6544691.
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Neuropsychiatric Safety and Efficacy of Varenicline, Bupropion, and Nicotine Patch in Smokers With Psychotic, Anxiety, and Mood Disorders in the EAGLES Trial. J Clin Psychopharmacol. 2019 Mar/Apr; 39(2):108-116. Evins AE, Benowitz NL, West R, Russ C, McRae T, Lawrence D, Krishen A, St Aubin L, Maravic MC, Anthenelli RM. PMID: 30811371; PMCID: PMC6488024.
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Vascular Aging Is Accelerated in Flight Attendants With Occupational Secondhand Smoke Exposure. J Occup Environ Med. 2019 03; 61(3):197-202. Wei J, Shufelt C, Oestreicher Stock E, Mills C, Dhawan S, Jacob R, Torbati T, Cook-Wiens G, Benowitz N, Jacob P, Ganz P, Bairey Merz CN, Redberg R. PMID: 30475308; PMCID: PMC6698135.
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Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity. Addict Biol. 2020 01; 25(1):e12741. El-Boraie A, Taghavi T, Chenoweth MJ, Fukunaga K, Mushiroda T, Kubo M, Lerman C, Nollen NL, Benowitz NL, Tyndale RF. PMID: 30815984; PMCID: PMC7527027.
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Loperamide associated torsades de pointes, in the setting of complete heart block at marginally supratherapeutic dosing (20mg/day). Clin Toxicol (Phila). 2019 11; 57(11):1123-1124. Goodnough R, Nomura M, Badea A, Lynch KL, Benowitz NL, Tsutaoka B. PMID: 30777457.
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Butanediol Conversion to Gamma-Hydroxybutyrate Markedly Reduced by the Alcohol Dehydrogenase Blocker Fomepizole. Clin Pharmacol Ther. 2019 05; 105(5):1196-1203. Liakoni E, Gugelmann H, Dempsey DA, Wiegand TJ, Havel C, Jacob P, Benowitz NL. PMID: 30450642; PMCID: PMC6465153.
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Evaluating the temporal relationships between withdrawal symptoms and smoking relapse. Psychol Addict Behav. 2019 Mar; 33(2):105-116. Robinson JD, Li L, Chen M, Lerman C, Tyndale RF, Schnoll RA, Hawk LW, George TP, Benowitz NL, Cinciripini PM. PMID: 30614717; PMCID: PMC6405298.
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Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein. PLoS One. 2019; 14(1):e0210104. Chen M, Carmella SG, Sipe C, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami D, Hecht SS. PMID: 30608961; PMCID: PMC6319718.
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Managing Cannabis Use in Patients With Cardiovascular Disease. Can J Cardiol. 2019 02; 35(2):138-141. Benowitz NL. PMID: 30760417.
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Identification and quantification of electronic cigarette exhaled aerosol residue chemicals in field sites. Environ Res. 2019 03; 170:351-358. Khachatoorian C, Jacob P, Sen A, Zhu Y, Benowitz NL, Talbot P. PMID: 30623881; PMCID: PMC6410739.
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Reprint of: Prevention and Treatment of Tobacco Use: JACC Health Promotion Series. J Am Coll Cardiol. 2018 12 11; 72(23 Pt B):2964-2979. Kalkhoran S, Benowitz NL, Rigotti NA. PMID: 30522631.
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2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment: A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol. 2018 12 25; 72(25):3332-3365. Barua RS, Rigotti NA, Benowitz NL, Cummings KM, Jazayeri MA, Morris PB, Ratchford EV, Sarna L, Stecker EC, Wiggins BS. PMID: 30527452.
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Urine 4-(methylnitrosamino)-1-(3) pyridyl-1-butanol and cotinine in Alaska native postpartum women and neonates comparing smokers and smokeless tobacco users. Int J Circumpolar Health. 2018 Dec; 77(1):1528125. Benowitz NL, Flanagan CA, Thomas TK, Koller KR, Wolfe AW, Renner CC, Hughes C, Decker PA, Hatsukami DK, Murphy NJ, Patten C. PMID: 30325719; PMCID: PMC6197029.
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Effects of Nicotine Metabolic Rate on Withdrawal Symptoms and Response to Cigarette Smoking After Abstinence. Clin Pharmacol Ther. 2019 03; 105(3):641-651. Liakoni E, Edwards KC, St Helen G, Nardone N, Dempsey DA, Tyndale RF, Benowitz NL. PMID: 30242831; PMCID: PMC7967935.
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Biomarker feedback intervention for smoking cessation among Alaska Native pregnant women: Randomized pilot study. Patient Educ Couns. 2019 Mar; 102(3):528-535. Patten CA, Koller KR, Flanagan CA, Hiratsuka VY, Hughes CA, Wolfe AW, Decker PA, Fruth K, Brockman TA, Korpela M, Gamez D, Bronars C, Murphy NJ, Hatsukami D, Benowitz NL, Thomas TK. PMID: 30391300; PMCID: PMC6421103.
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Effect of γ-hydroxybutyrate (GHB) on driving as measured by a driving simulator. Psychopharmacology (Berl). 2018 Nov; 235(11):3223-3232. Liakoni E, Dempsey DA, Meyers M, Murphy NG, Fiorentino D, Havel C, Haller C, Benowitz NL. PMID: 30232528; PMCID: PMC6457903.
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Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial. JAMA. 2018 09 04; 320(9):880-891. Hatsukami DK, Luo X, Jensen JA, al'Absi M, Allen SS, Carmella SG, Chen M, Cinciripini PM, Denlinger-Apte R, Drobes DJ, Koopmeiners JS, Lane T, Le CT, Leischow S, Luo K, McClernon FJ, Murphy SE, Paiano V, Robinson JD, Severson H, Sipe C, Strasser AA, Strayer LG, Tang MK, Vandrey R, Hecht SS, Benowitz NL, Donny EC. PMID: 30193275; PMCID: PMC6372240.
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IQOS: examination of Philip Morris International's claim of reduced exposure. Tob Control. 2018 11; 27(Suppl 1):s30-s36. St Helen G, Jacob Iii P, Nardone N, Benowitz NL. PMID: 30158205; PMCID: PMC6252487.
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Electronic cigarette chemicals transfer from a vape shop to a nearby business in a multiple-tenant retail building. Tob Control. 2019 09; 28(5):519-525. Khachatoorian C, Jacob Iii P, Benowitz NL, Talbot P. PMID: 30158206; PMCID: PMC6458093.
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Prevention and Treatment of Tobacco Use: JACC Health Promotion Series. J Am Coll Cardiol. 2018 08 28; 72(9):1030-1045. Kalkhoran S, Benowitz NL, Rigotti NA. PMID: 30139432; PMCID: PMC6261256.
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Association of Reduced Nicotine Content Cigarettes With Smoking Behaviors and Biomarkers of Exposure Among Slow and Fast Nicotine Metabolizers: A Nonrandomized Clinical Trial. JAMA Netw Open. 2018 08; 1(4):e181346. Mercincavage M, Lochbuehler K, Wileyto EP, Benowitz NL, Tyndale RF, Lerman C, Strasser AA. PMID: 30627706; PMCID: PMC6322845.
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Another Article About E-Cigarettes: Why Should I Care? J Am Heart Assoc. 2018 07 14; 7(14). Cummings KM, Morris PB, Benowitz NL. PMID: 30007935; PMCID: PMC6064866.
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Stimulant drugs are associated with violent and penetrating trauma. Am J Emerg Med. 2019 04; 37(4):645-650. Armenian P, Effron Z, Garbi N, Dirks R, Benowitz NL, Gerona RR. PMID: 30914133.
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Nicotine Reduction Strategy: State of the science and challenges to tobacco control policy and FDA tobacco product regulation. Prev Med. 2018 12; 117:5-7. Benowitz NL, Henningfield JE. PMID: 29944901.
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Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma. Thorax. 2018 11; 73(11):1041-1048. Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodríguez-Cintrón W, Rodríguez-Santana JR, Kumar R, Brigino-Buenaventura E, Sen S, Lenoir MA, Williams LK, Benowitz NL, Balmes JR, Eisen EA, Burchard EG. PMID: 29899038; PMCID: PMC6225993.
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Response to "Rapid Nicotine Ratio and Successful Quitting: Acceptable Explanation" by the Authors of "Nicotine Metabolite Ratio (NMR) Prospectively Predicts Smoking Relapse: Longitudinal Findings from ITC Surveys in Five Countries". Nicotine Tob Res. 2018 06 07; 20(7):909. Fix BV, O'Connor RJ, Heckman BW, Benowitz N, Cummings MK, Fong GT, Thrasher JF. PMID: 29878262.
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The Healing and Empowering Alaskan Lives Toward Healthy-Hearts (HEALTHH) Project: Study protocol for a randomized controlled trial of an intervention for tobacco use and other cardiovascular risk behaviors for Alaska Native People. Contemp Clin Trials. 2018 Aug; 71:40-46. Prochaska JJ, Epperson A, Skan J, Oppezzo M, Barnett P, Delucchi K, Schnellbaecher M, Benowitz NL. PMID: 29864548; PMCID: PMC6636857.
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Impact of e-liquid flavors on e-cigarette vaping behavior. Drug Alcohol Depend. 2018 Aug 01; 189:42-48. St Helen G, Shahid M, Chu S, Benowitz NL. PMID: 29879680; PMCID: PMC6211798.
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Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine. Cancer Epidemiol Biomarkers Prev. 2018 09; 27(9):1083-1090. Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL. PMID: 29853481; PMCID: PMC6125195.
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Cardiovascular Safety of Varenicline, Bupropion, and Nicotine Patch in Smokers: A Randomized Clinical Trial. JAMA Intern Med. 2018 05 01; 178(5):622-631. Benowitz NL, Pipe A, West R, Hays JT, Tonstad S, McRae T, Lawrence D, St Aubin L, Anthenelli RM. PMID: 29630702; PMCID: PMC6145797.
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Factors associated with the efficacy of smoking cessation treatments and predictors of smoking abstinence in EAGLES. Addiction. 2018 08; 113(8):1507-1516. West R, Evins AE, Benowitz NL, Russ C, McRae T, Lawrence D, St Aubin L, Krishen A, Maravic MC, Anthenelli RM. PMID: 29508470; PMCID: PMC6055735.
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Whether to push or pull? Nicotine reduction and non-combusted alternatives - Two strategies for reducing smoking and improving public health. Prev Med. 2018 12; 117:8-14. Smith TT, Hatsukami DK, Benowitz NL, Colby SM, McClernon FJ, Strasser AA, Tidey JW, White CM, Donny EC. PMID: 29604326; PMCID: PMC6163095.
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Effects of reduced nicotine content cigarettes on individual withdrawal symptoms over time and during abstinence. Exp Clin Psychopharmacol. 2018 06; 26(3):223-232. Dermody SS, McClernon FJ, Benowitz N, Luo X, Tidey JW, Smith TT, Vandrey R, Hatsukami D, Donny EC. PMID: 29504780; PMCID: PMC5986583.
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Adolescent Exposure to Toxic Volatile Organic Chemicals From E-Cigarettes. Pediatrics. 2018 04; 141(4). Rubinstein ML, Delucchi K, Benowitz NL, Ramo DE. PMID: 29507165; PMCID: PMC5869331.
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Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients. Am J Respir Crit Care Med. 2018 03 01; 197(5):621-631. Panzer AR, Lynch SV, Langelier C, Christie JD, McCauley K, Nelson M, Cheung CK, Benowitz NL, Cohen MJ, Calfee CS. PMID: 29035085; PMCID: PMC6005235.
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Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice. Clin Sci (Lond). 2018 02 28; 132(4):475-488. Hang B, Wang Y, Huang Y, Wang P, Langley SA, Bi L, Sarker AH, Schick SF, Havel C, Jacob P, Benowitz N, Destaillats H, Tang X, Xia Y, Jen KY, Gundel LA, Mao JH, Snijders AM. PMID: 29440622; PMCID: PMC6365648.
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Comparison of Urine 4-(Methylnitrosamino)-1-(3)Pyridyl-1-Butanol and Cotinine for Assessment of Active and Passive Smoke Exposure in Urban Adolescents. Cancer Epidemiol Biomarkers Prev. 2018 03; 27(3):254-261. Benowitz NL, Nardone N, Jain S, Dempsey DA, Addo N, St Helen G, Jacob P. PMID: 29475963; PMCID: PMC5835192.
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Tobacco Consumption and Toxicant Exposure of Cigarette Smokers Using Electronic Cigarettes. Nicotine Tob Res. 2018 01 05; 20(2):206-214. Pulvers K, Emami AS, Nollen NL, Romero DR, Strong DR, Benowitz NL, Ahluwalia JS. PMID: 28003511; PMCID: PMC6251645.
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Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma. J Natl Cancer Inst. 2017 12 01; 109(12). Song MA, Benowitz NL, Berman M, Brasky TM, Cummings KM, Hatsukami DK, Marian C, O'Connor R, Rees VW, Woroszylo C, Shields PG. PMID: 28525914; PMCID: PMC6059254.
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Slower nicotine metabolism among postmenopausal Polish smokers. Pharmacol Rep. 2018 Jun; 70(3):434-438. Kosmider L, Delijewski M, Koszowski B, Sobczak A, Benowitz NL, Goniewicz ML. PMID: 29627689.
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Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences. Addiction. 2018 03; 113(3):509-523. Chenoweth MJ, Ware JJ, Zhu AZX, Cole CB, Cox LS, Nollen N, Ahluwalia JS, Benowitz NL, Schnoll RA, Hawk LW, Cinciripini PM, George TP, Lerman C, Knight J, Tyndale RF, PGRN-PNAT Research Group. PMID: 28921760; PMCID: PMC5807179.
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An Electronic Cigarette Vaping Machine for the Characterization of Aerosol Delivery and Composition. Nicotine Tob Res. 2017 Oct 01; 19(10):1224-1231. Havel CM, Benowitz NL, Jacob P, St Helen G. PMID: 27281605; PMCID: PMC5896538.
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Urine Cotinine Screening Detects Nearly Ubiquitous Tobacco Smoke Exposure in Urban Adolescents. Nicotine Tob Res. 2017 Sep 01; 19(9):1048-1054. Benowitz NL, Jain S, Dempsey DA, Nardone N, Helen GS, Jacob P. PMID: 28031377; PMCID: PMC5896471.
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Nicotine Metabolite Ratio (NMR) Prospectively Predicts Smoking Relapse: Longitudinal Findings From ITC Surveys in Five Countries. Nicotine Tob Res. 2017 Sep 01; 19(9):1040-1047. Fix BV, O'Connor RJ, Benowitz N, Heckman BW, Cummings KM, Fong GT, Thrasher JF. PMID: 28387850; PMCID: PMC5896535.
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Tobacco toxicant exposure in cigarette smokers who use or do not use other tobacco products. Drug Alcohol Depend. 2017 10 01; 179:330-336. Nollen NL, Mayo MS, Clark L, Cox LS, Khariwala SS, Pulvers K, Benowitz NL, Ahluwalia JS. PMID: 28843083; PMCID: PMC5599364.
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Comprehensive Nicotine Regulation to End the Combustible Tobacco Epidemic. Ann Intern Med. 2017 Nov 21; 167(10):736-737. Benowitz NL. PMID: 28806818.
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Emissions from Electronic Cigarettes: Assessing Vapers' Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts. Environ Sci Technol. 2017 Aug 15; 51(16):9271-9279. Logue JM, Sleiman M, Montesinos VN, Russell ML, Litter MI, Benowitz NL, Gundel LA, Destaillats H. PMID: 28766331.
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Urinary NNAL in hookah smokers and non-smokers after attending a hookah social event in a hookah lounge or a private home. Regul Toxicol Pharmacol. 2017 Oct; 89:74-82. Kassem NOF, Kassem NO, Liles S, Jackson SR, Chatfield DA, Jacob P, Benowitz NL, Hovell MF. PMID: 28716579; PMCID: PMC5582991.
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Measures and predictors of varenicline adherence in the treatment of nicotine dependence. Addict Behav. 2017 12; 75:122-129. Peng AR, Morales M, Wileyto EP, Hawk LW, Cinciripini P, George TP, Benowitz NL, Nollen NL, Lerman C, Tyndale RF, Schnoll R. PMID: 28728040; PMCID: PMC5581992.
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Impact of e-liquid flavors on nicotine intake and pharmacology of e-cigarettes. Drug Alcohol Depend. 2017 09 01; 178:391-398. St Helen G, Dempsey DA, Havel CM, Jacob P, Benowitz NL. PMID: 28704768; PMCID: PMC5565733.
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Nicotine biomarkers and rate of nicotine metabolism among cigarette smokers taking buprenorphine for opioid dependency. Drug Alcohol Depend. 2017 09 01; 178:267-270. Gubner NR, Guydish J, Humfleet GL, Benowitz NL, Hall SM. PMID: 28683421; PMCID: PMC5553616.
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Biomarkers of exposure to new and emerging tobacco delivery products. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L425-L452. Schick SF, Blount BC, Jacob P, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A. PMID: 28522563; PMCID: PMC5626373.
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Effect of UGT2B10, UGT2B17, FMO3, and OCT2 genetic variation on nicotine and cotinine pharmacokinetics and smoking in African Americans. Pharmacogenet Genomics. 2017 04; 27(4):143-154. Taghavi T, St Helen G, Benowitz NL, Tyndale RF. PMID: 28178031; PMCID: PMC5346034.
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Cardiovascular effects of electronic cigarettes. Nat Rev Cardiol. 2017 Aug; 14(8):447-456. Benowitz NL, Fraiman JB. PMID: 28332500; PMCID: PMC5519136.
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Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds among recently pregnant rural Guatemalan women cooking and heating with solid fuels. Int J Hyg Environ Health. 2017 06; 220(4):726-735. Weinstein JR, Asteria-Peñaloza R, Diaz-Artiga A, Davila G, Hammond SK, Ryde IT, Meyer JN, Benowitz N, Thompson LM. PMID: 28320639; PMCID: PMC5474125.
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Early exposure to thirdhand cigarette smoke affects body mass and the development of immunity in mice. Sci Rep. 2017 02 03; 7:41915. Hang B, Snijders AM, Huang Y, Schick SF, Wang P, Xia Y, Havel C, Jacob P, Benowitz N, Destaillats H, Gundel LA, Mao JH. PMID: 28157226; PMCID: PMC5291208.
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Thirdhand Smoke: New Evidence, Challenges, and Future Directions. Chem Res Toxicol. 2017 01 17; 30(1):270-294. Jacob P, Benowitz NL, Destaillats H, Gundel L, Hang B, Martins-Green M, Matt GE, Quintana PJ, Samet JM, Schick SF, Talbot P, Aquilina NJ, Hovell MF, Mao JH, Whitehead TP. PMID: 28001376; PMCID: PMC5501723.
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Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose. J Emerg Med. 2017 May; 52(5):680-683. Vo KT, Horng H, Smollin CG, Benowitz NL. PMID: 27979642.
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Reducing nicotine exposure results in weight gain in smokers randomised to very low nicotine content cigarettes. Tob Control. 2017 03; 26(e1):e43-e48. Rupprecht LE, Koopmeiners JS, Dermody SS, Oliver JA, al'Absi M, Benowitz NL, Denlinger-Apte R, Drobes DJ, Hatsukami D, McClernon FJ, Pacek LR, Smith TT, Sved AF, Tidey J, Vandrey R, Donny EC. PMID: 27856940; PMCID: PMC5428392.
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Perceived risks and reasons to smoke cigarettes during pregnancy among Alaska native women. Ethn Health. 2018 Jan; 23(1):33-42. Bronars C, Patten C, Koller K, Hatsukami D, Flanagan CA, Decker PA, Hanson A, Wolfe A, Hughes C, Benowitz N, Murphy NJ, Thomas T. PMID: 27842438; PMCID: PMC5986277.
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Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 11; 14(11):1430-1468. Shields PG, Herbst RS, Arenberg D, Benowitz NL, Bierut L, Luckart JB, Cinciripini P, Collins B, David S, Davis J, Hitsman B, Hyland A, Lang M, Leischow S, Park ER, Purcell WT, Selzle J, Silber A, Spencer S, Tanvetyanon T, Tiep B, Tindle HA, Tucker-Seeley R, Urbanic J, Hooper MW, Weksler B, Whitlock CW, Wood DE, Burns J, Scavone J. PMID: 27799513.
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Nicotine Replacement, Topography, and Smoking Phenotypes of E-cigarettes. Tob Regul Sci. 2016 Oct; 2(4):352-362. Strasser AA, Souprountchouk V, Kaufmann A, Blazekovic S, Leone F, Benowitz NL, Schnoll RA. PMID: 27942543; PMCID: PMC5142626.
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Nicotine Delivery and Vaping Behavior During ad Libitum E-cigarette Access. Tob Regul Sci. 2016 Oct; 2(4):363-376. St Helen G, Ross KC, Dempsey DA, Havel CM, Jacob P, Benowitz NL. PMID: 28393086; PMCID: PMC5381821.
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"You have the right to protect your health": Perceptions of Secondhand Smoke and Exposure Mitigation Strategies in Low-Income Patients With Heart Disease, San Francisco, 2011-2012. Prev Chronic Dis. 2016 08 25; 13:E116. Brown-Johnson CG, Oppezzo M, Benowitz NL, Prochaska JJ. PMID: 27560724; PMCID: PMC5003531.
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Reduced nicotine content cigarettes, e-cigarettes and the cigarette end game. Addiction. 2017 01; 112(1):6-7. Benowitz NL, Donny EC, Hatsukami DK. PMID: 27555354; PMCID: PMC5518737.
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Exposure to Nicotine and Selected Toxicants in Cigarette Smokers Who Switched to Electronic Cigarettes: A Longitudinal Within-Subjects Observational Study. Nicotine Tob Res. 2017 Feb; 19(2):160-167. Goniewicz ML, Gawron M, Smith DM, Peng M, Jacob P, Benowitz NL. PMID: 27613896; PMCID: PMC5234360.
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Effects of 6-Week Use of Reduced-Nicotine Content Cigarettes in Smokers With and Without Elevated Depressive Symptoms. Nicotine Tob Res. 2017 01; 19(1):59-67. Tidey JW, Pacek LR, Koopmeiners JS, Vandrey R, Nardone N, Drobes DJ, Benowitz NL, Dermody SS, Lemieux A, Denlinger RL, Cassidy R, al'Absi M, Hatsukami DK, Donny EC. PMID: 27613885; PMCID: PMC5157715.
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Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes. Addiction. 2016 12; 111(12):2208-2216. Nardone N, Donny EC, Hatsukami DK, Koopmeiners JS, Murphy SE, Strasser AA, Tidey JW, Vandrey R, Benowitz NL. PMID: 27367436; PMCID: PMC5203964.
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Disposition kinetics and metabolism of nicotine and cotinine in African American smokers: impact of CYP2A6 genetic variation and enzymatic activity. Pharmacogenet Genomics. 2016 07; 26(7):340-50. Benowitz NL, St Helen G, Dempsey DA, Jacob P, Tyndale RF. PMID: 27035242; PMCID: PMC4892970.
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E-cigarette use results in suppression of immune and inflammatory-response genes in nasal epithelial cells similar to cigarette smoke. Am J Physiol Lung Cell Mol Physiol. 2016 07 01; 311(1):L135-44. Martin EM, Clapp PW, Rebuli ME, Pawlak EA, Glista-Baker E, Benowitz NL, Fry RC, Jaspers I. PMID: 27288488; PMCID: PMC4967187.
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Fetal Exposure to Carcinogens With Tobacco Use in Pregnancy: Phase 1 MAW Study Findings. Nicotine Tob Res. 2016 11; 18(11):2162-2168. Flanagan CA, Koller KR, Wolfe AW, Thomas TK, Benowitz NL, Renner CC, Hughes C, Hatsukami DK, Bronars C, Murphy NJ, Day G, Decker PA, Patten CA. PMID: 27190400; PMCID: PMC5055741.
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Racial differences in the relationship between rate of nicotine metabolism and nicotine intake from cigarette smoking. Pharmacol Biochem Behav. 2016 09; 148:1-7. Ross KC, Gubner NR, Tyndale RF, Hawk LW, Lerman C, George TP, Cinciripini P, Schnoll RA, Benowitz NL. PMID: 27180107; PMCID: PMC4972680.
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Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries. Nicotine Tob Res. 2016 09; 18(9):1837-1844. Baurley JW, Edlund CK, Pardamean CI, Conti DV, Krasnow R, Javitz HS, Hops H, Swan GE, Benowitz NL, Bergen AW. PMID: 27113016; PMCID: PMC4978985.
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Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet. 2016 Jun 18; 387(10037):2507-20. Anthenelli RM, Benowitz NL, West R, St Aubin L, McRae T, Lawrence D, Ascher J, Russ C, Krishen A, Evins AE. PMID: 27116918.
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Cessation of alcohol consumption decreases rate of nicotine metabolism in male alcohol-dependent smokers. Drug Alcohol Depend. 2016 Jun 01; 163:157-64. Gubner NR, Kozar-Konieczna A, Szoltysek-Boldys I, Slodczyk-Mankowska E, Goniewicz J, Sobczak A, Jacob P, Benowitz NL, Goniewicz ML. PMID: 27107849; PMCID: PMC4880506.
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Nicotine and Anatabine Exposure from Very Low Nicotine Content Cigarettes. Tob Regul Sci. 2016 Apr; 2(2):186-203. Denlinger RL, Smith TT, Murphy SE, Koopmeiners JS, Benowitz NL, Hatsukami DK, Pacek LR, Colino C, Cwalina SN, Donny EC. PMID: 29600258; PMCID: PMC5870904.
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The Influence of Puff Characteristics, Nicotine Dependence, and Rate of Nicotine Metabolism on Daily Nicotine Exposure in African American Smokers. Cancer Epidemiol Biomarkers Prev. 2016 06; 25(6):936-43. Ross KC, Dempsey DA, St Helen G, Delucchi K, Benowitz NL. PMID: 27030603; PMCID: PMC4891233.
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Acute Effect of Hookah Smoking on the Human Coronary Microcirculation. Am J Cardiol. 2016 06 01; 117(11):1747-54. Nelson MD, Rezk-Hanna M, Rader F, Mason OR, Tang X, Shidban S, Rosenberry R, Benowitz NL, Tashkin DP, Elashoff RM, Lindner JR, Victor RG. PMID: 27067622; PMCID: PMC5689082.
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Cardiovascular toxicity of nicotine: Implications for electronic cigarette use. Trends Cardiovasc Med. 2016 08; 26(6):515-23. Benowitz NL, Burbank AD. PMID: 27079891; PMCID: PMC4958544.
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Minoxidil-Associated Pleuropericardial Effusion. J Gen Intern Med. 2016 09; 31(9):1105. Brondfield M, Wu L, Benowitz N. PMID: 26951281; PMCID: PMC4978667.
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Thirdhand Smoke: State of the Science and a Call for Policy Expansion. Public Health Rep. 2016 Mar-Apr; 131(2):233-8. Northrup TF, Jacob P, Benowitz NL, Hoh E, Quintana PJ, Hovell MF, Matt GE, Stotts AL. PMID: 26957657; PMCID: PMC4765971.
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A clinical trial to examine disparities in quitting between African-American and White adult smokers: Design, accrual, and baseline characteristics. Contemp Clin Trials. 2016 Mar; 47:12-21. Nollen NL, Cox LS, Yu Q, Ellerbeck EF, Scheuermann TS, Benowitz NL, Tyndale RF, Mayo MS, Ahluwalia JS. PMID: 26667382; PMCID: PMC4818177.
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Thirdhand smoke contamination in hospital settings: assessing exposure risk for vulnerable paediatric patients. Tob Control. 2016 11; 25(6):619-623. Northrup TF, Khan AM, Jacob P, Benowitz NL, Hoh E, Hovell MF, Matt GE, Stotts AL. PMID: 26635031; PMCID: PMC4893002.
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Nicotine delivery, retention and pharmacokinetics from various electronic cigarettes. Addiction. 2016 Mar; 111(3):535-44. St Helen G, Havel C, Dempsey DA, Jacob P, Benowitz NL. PMID: 26430813; PMCID: PMC4749433.
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Randomized Trial of Reduced-Nicotine Standards for Cigarettes. N Engl J Med. 2015 Oct; 373(14):1340-9. Donny EC, Denlinger RL, Tidey JW, Koopmeiners JS, Benowitz NL, Vandrey RG, al'Absi M, Carmella SG, Cinciripini PM, Dermody SS, Drobes DJ, Hecht SS, Jensen J, Lane T, Le CT, McClernon FJ, Montoya ID, Murphy SE, Robinson JD, Stitzer ML, Strasser AA, Tindle H, Hatsukami DK. PMID: 26422724; PMCID: PMC4642683.
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Cardiovascular Effects of Exposure to Cigarette Smoke and Electronic Cigarettes: Clinical Perspectives From the Prevention of Cardiovascular Disease Section Leadership Council and Early Career Councils of the American College of Cardiology. J Am Coll Cardiol. 2015 Sep 22; 66(12):1378-91. Morris PB, Ference BA, Jahangir E, Feldman DN, Ryan JJ, Bahrami H, El-Chami MF, Bhakta S, Winchester DE, Al-Mallah MH, Sanchez Shields M, Deedwania P, Mehta LS, Phan BA, Benowitz NL. PMID: 26383726.
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Smoking cessation and the cardiovascular patient. Curr Opin Cardiol. 2015 Sep; 30(5):506-11. Prochaska JJ, Benowitz NL. PMID: 26196657; PMCID: PMC4624444.
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Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. Crit Care Med. 2015 Sep; 43(9):1790-7. Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB. PMID: 26010690; PMCID: PMC4737582.
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The Past, Present, and Future of Nicotine Addiction Therapy. Annu Rev Med. 2016; 67:467-86. Prochaska JJ, Benowitz NL. PMID: 26332005; PMCID: PMC5117107.
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Effect of reducing the nicotine content of cigarettes on cigarette smoking behavior and tobacco smoke toxicant exposure: 2-year follow up. Addiction. 2015 Oct; 110(10):1667-75. Benowitz NL, Nardone N, Dains KM, Hall SM, Stewart S, Dempsey D, Jacob P. PMID: 26198394; PMCID: PMC4565734.
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Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. PLoS One. 2015; 10(7):e0126113. Bergen AW, Michel M, Nishita D, Krasnow R, Javitz HS, Conneely KN, Lessov-Schlaggar CN, Hops H, Zhu AZ, Baurley JW, McClure JB, Hall SM, Baker TB, Conti DV, Benowitz NL, Lerman C, Tyndale RF, Swan GE, Transdisciplinary Research in Cancer of the Lung Research Team. PMID: 26132489; PMCID: PMC4488893.
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Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking. PLoS One. 2015; 10(5):e0128109. Tyndale RF, Zhu AZ, George TP, Cinciripini P, Hawk LW, Schnoll RA, Swan GE, Benowitz NL, Heitjan DF, Lerman C, PGRN-PNAT Research Group. PMID: 26010901; PMCID: PMC4444267.
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Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation. Cancer Epidemiol Biomarkers Prev. 2015 Aug; 24(8):1239-46. Tanner JA, Novalen M, Jatlow P, Huestis MA, Murphy SE, Kaprio J, Kankaanpää A, Galanti L, Stefan C, George TP, Benowitz NL, Lerman C, Tyndale RF. PMID: 26014804; PMCID: PMC4526326.
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Nicotine Metabolite Ratio Is Associated With Lozenge Use But Not Quitting in Smokeless Tobacco Users. Nicotine Tob Res. 2016 Mar; 18(3):366-70. Ebbert JO, Severson HH, Danaher BG, Benowitz NL, Schroeder DR. PMID: 25977408; PMCID: PMC6095223.
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Genetic and phenotypic variation in UGT2B17, a testosterone-metabolizing enzyme, is associated with BMI in males. Pharmacogenet Genomics. 2015 May; 25(5):263-9. Zhu AZ, Cox LS, Ahluwalia JS, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF. PMID: 25794161; PMCID: PMC4382380.
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Tobacco alkaloids and tobacco-specific nitrosamines in dust from homes of smokeless tobacco users, active smokers, and nontobacco users. Chem Res Toxicol. 2015 May 18; 28(5):1007-14. Whitehead TP, Havel C, Metayer C, Benowitz NL, Jacob P. PMID: 25794360; PMCID: PMC4827423.
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Guidance to employers on integrating e-cigarettes/electronic nicotine delivery systems into tobacco worksite policy. J Occup Environ Med. 2015 Mar; 57(3):334-43. Whitsel LP, Benowitz N, Bhatnagar A, Bullen C, Goldstein F, Matthias-Gray L, Grossmeier J, Harris J, Isaac F, Loeppke R, Manley M, Moseley K, Niemiec T, O'Brien V, Palma-Davis L, Pronk N, Pshock J, Stave GM, Terry P. PMID: 25742539.
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Response to letter regarding article, "Electronic cigarettes: a scientific review". Circulation. 2015 Feb 10; 131(6):e342. Grana R, Benowitz N, Glantz S. PMID: 25815391.
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Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial. Lancet Respir Med. 2015 Feb; 3(2):131-138. Lerman C, Schnoll RA, Hawk LW, Cinciripini P, George TP, Wileyto EP, Swan GE, Benowitz NL, Heitjan DF, Tyndale RF, PGRN-PNAT Research Group. PMID: 25588294; PMCID: PMC4480925.
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Nicotine Dependence, Nicotine Metabolism, and the Extent of Compensation in Response to Reduced Nicotine Content Cigarettes. Nicotine Tob Res. 2015 Sep; 17(9):1167-72. Bandiera FC, Ross KC, Taghavi S, Delucchi K, Tyndale RF, Benowitz NL. PMID: 25555385; PMCID: PMC4542742.
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Secondhand tobacco smoke exposure among hospitalized nonsmokers with coronary heart disease. JAMA Intern Med. 2015 Jan; 175(1):133-6. Japuntich SJ, Eilers MA, Shenhav S, Park ER, Winickoff JP, Benowitz NL, Rigotti NA. PMID: 25383761.
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Different profiles of carcinogen exposure in Chinese compared with US cigarette smokers. Tob Control. 2015 Dec; 24(e4):e258-63. Benowitz NL, Gan Q, Goniewicz ML, Lu W, Xu J, Li X, Jacob P, Glantz S. PMID: 25535294; PMCID: PMC4476967.
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Compensatory smoking from gradual and immediate reduction in cigarette nicotine content. Cancer Epidemiol Biomarkers Prev. 2015 Feb; 24(2):472-6. Hatsukami DK, Donny EC, Koopmeiners JS, Benowitz NL. PMID: 25515551; PMCID: PMC4324025.
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Biochemical estimation of noncompliance with smoking of very low nicotine content cigarettes. Cancer Epidemiol Biomarkers Prev. 2015 Feb; 24(2):331-5. Benowitz NL, Nardone N, Hatsukami DK, Donny EC. PMID: 25416718; PMCID: PMC4323626.
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Intake of toxic and carcinogenic volatile organic compounds from secondhand smoke in motor vehicles. Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12):2774-82. St Helen G, Jacob P, Peng M, Dempsey DA, Hammond SK, Benowitz NL. PMID: 25398951; PMCID: PMC4257856.
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Cardiogenic shock after use of fluoroamphetamine confirmed with serum and urine levels. Clin Toxicol (Phila). 2014 Dec; 52(10):1292-5. Al-Abri S, Meier KH, Colby JM, Smollin CG, Benowitz NL. PMID: 25350468.
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UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers. Cancer Epidemiol Biomarkers Prev. 2015 Jan; 24(1):94-104. Wassenaar CA, Conti DV, Das S, Chen P, Cook EH, Ratain MJ, Benowitz NL, Tyndale RF. PMID: 25277794; PMCID: PMC4294984.
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Gene variants in CYP2C19 are associated with altered in vivo bupropion pharmacokinetics but not bupropion-assisted smoking cessation outcomes. Drug Metab Dispos. 2014 Nov; 42(11):1971-7. Zhu AZ, Zhou Q, Cox LS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 25187485; PMCID: PMC4201132.
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Prevalence and impact of active and passive cigarette smoking in acute respiratory distress syndrome. Crit Care Med. 2014 Sep; 42(9):2058-68. Hsieh SJ, Zhuo H, Benowitz NL, Thompson BT, Liu KD, Matthay MA, Calfee CS, National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network, National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome Network. PMID: 24942512; PMCID: PMC4134734.
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Electronic cigarettes: a policy statement from the American Heart Association. Circulation. 2014 Oct 14; 130(16):1418-36. Bhatnagar A, Whitsel LP, Ribisl KM, Bullen C, Chaloupka F, Piano MR, Robertson RM, McAuley T, Goff D, Benowitz N, American Heart Association Advocacy Coordinating Committee, Council on Cardiovascular and Stroke Nur. PMID: 25156991; PMCID: PMC7643636.
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Organic cation transporter variation and response to smoking cessation therapies. Nicotine Tob Res. 2014 Dec; 16(12):1638-46. Bergen AW, Javitz HS, Krasnow R, Michel M, Nishita D, Conti DV, Edlund CK, Kwok PY, McClure JB, Kim RB, Hall SM, Tyndale RF, Baker TB, Benowitz NL, Swan GE. PMID: 25143296; PMCID: PMC4296186.
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Electronic cigarettes: review of use, content, safety, effects on smokers and potential for harm and benefit. Addiction. 2014 Nov; 109(11):1801-10. Hajek P, Etter JF, Benowitz N, Eissenberg T, McRobbie H. PMID: 25078252; PMCID: PMC4487785.
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Reduced nicotine product standards for combustible tobacco: building an empirical basis for effective regulation. Prev Med. 2014 Nov; 68:17-22. Donny EC, Hatsukami DK, Benowitz NL, Sved AF, Tidey JW, Cassidy RN. PMID: 24967958; PMCID: PMC4253911.
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Nicotine and carcinogen exposure after water pipe smoking in hookah bars. Cancer Epidemiol Biomarkers Prev. 2014 Jun; 23(6):1055-66. St Helen G, Benowitz NL, Dains KM, Havel C, Peng M, Jacob P. PMID: 24836469; PMCID: PMC4047652.
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E-cigarettes: a scientific review. Circulation. 2014 May 13; 129(19):1972-86. Grana R, Benowitz N, Glantz SA. PMID: 24821826; PMCID: PMC4018182.
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Electronic cigarettes. Cardiology patient page. Circulation. 2014 May 13; 129(19):e490-2. Grana RA, Ling PM, Benowitz N, Glantz S. PMID: 24821830; PMCID: PMC4074376.
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A comparison of nicotine biomarkers and smoking patterns in daily and nondaily smokers. Cancer Epidemiol Biomarkers Prev. 2014 Jul; 23(7):1264-72. Shiffman S, Dunbar MS, Benowitz NL. PMID: 24740202; PMCID: PMC4621008.
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Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers. Clin Pharmacol Ther. 2014 Aug; 96(2):256-65. Zhu AZ, Zhou Q, Cox LS, David SP, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 24733007; PMCID: PMC4111775.
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Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers. Nicotine Tob Res. 2014 Jul; 16(7):961-75. Kassem NO, Daffa RM, Liles S, Jackson SR, Kassem NO, Younis MA, Mehta S, Chen M, Jacob P, Carmella SG, Chatfield DA, Benowitz NL, Matt GE, Hecht SS, Hovell MF. PMID: 24590387; PMCID: PMC4072898.
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Variation in P450 oxidoreductase (POR) A503V and flavin-containing monooxygenase (FMO)-3 E158K is associated with minor alterations in nicotine metabolism, but does not alter cigarette consumption. Pharmacogenet Genomics. 2014 Mar; 24(3):172-6. Chenoweth MJ, Zhu AZ, Sanderson Cox L, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 24448396; PMCID: PMC3985268.
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Novel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo. Pharmacogenet Genomics. 2014 Feb; 24(2):118-28. Piliguian M, Zhu AZ, Zhou Q, Benowitz NL, Ahluwalia JS, Sanderson Cox L, Tyndale RF. PMID: 24305170; PMCID: PMC3931261.
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Emerging nicotine delivery products. Implications for public health. Ann Am Thorac Soc. 2014 Feb; 11(2):231-5. Benowitz NL. PMID: 24575992.
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Cigarette smoke toxins deposited on surfaces: implications for human health. PLoS One. 2014; 9(1):e86391. Martins-Green M, Adhami N, Frankos M, Valdez M, Goodwin B, Lyubovitsky J, Dhall S, Garcia M, Egiebor I, Martinez B, Green HW, Havel C, Yu L, Liles S, Matt G, Destaillats H, Sleiman M, Gundel LA, Benowitz N, Jacob P, Hovell M, Winickoff JP, Curras-Collazo M. PMID: 24489722; PMCID: PMC3906039.
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Multiple risk-behavior profiles of smokers with serious mental illness and motivation for change. Health Psychol. 2014 Dec; 33(12):1518-29. Prochaska JJ, Fromont SC, Delucchi K, Young-Wolff KC, Benowitz NL, Hall S, Bonas T, Hall SM. PMID: 24467257; PMCID: PMC4425305.
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Clinical significance of early smoking withdrawal effects and their relationships with nicotine metabolism: preliminary results from a pilot study. Nicotine Tob Res. 2014 May; 16(5):615-20. Hendricks PS, Delucchi KL, Benowitz NL, Hall SM. PMID: 24353342; PMCID: PMC3977489.
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Cotinine and tobacco-specific carcinogen exposure among nondaily smokers in a multiethnic sample. Nicotine Tob Res. 2014 May; 16(5):600-5. Khariwala SS, Scheuermann TS, Berg CJ, Hayes RB, Nollen NL, Thomas JL, Guo H, Ahluwalia JS, Benowitz NL. PMID: 24297808; PMCID: PMC3988430.
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Factors associated with discontinuation of bupropion and counseling among African American light smokers in a randomized clinical trial. Ann Behav Med. 2013 Dec; 46(3):336-48. Nollen NL, Mayo MS, Ahluwalia JS, Tyndale RF, Benowitz NL, Faseru B, Buchanan TS, Cox LS. PMID: 23733379; PMCID: PMC3815499.
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Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. Clin Toxicol (Phila). 2013 Dec; 51(10):1230-4. Al-Abri SA, Orengo JP, Hayashi S, Thoren KL, Benowitz NL, Olson KR. PMID: 24131328.
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Nicotelline: a proposed biomarker and environmental tracer for particulate matter derived from tobacco smoke. Chem Res Toxicol. 2013 Nov 18; 26(11):1615-31. Jacob P, Goniewicz ML, Havel CM, Schick SF, Benowitz NL. PMID: 24125094; PMCID: PMC3929594.
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Levels of cotinine in dried blood specimens from newborns as a biomarker of maternal smoking close to the time of delivery. Am J Epidemiol. 2013 Dec 01; 178(11):1648-54. Yang J, Pearl M, Jacob P, DeLorenze GN, Benowitz NL, Yu L, Havel C, Kharrazi M. PMID: 24068198; PMCID: PMC3842901.
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Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion. Addiction. 2013 Dec; 108(12):2202-11. David SP, Strong DR, Leventhal AM, Lancaster MA, McGeary JE, Munafò MR, Bergen AW, Swan GE, Benowitz NL, Tyndale RF, Conti DV, Brown RA, Lerman C, Niaura R. PMID: 23941313; PMCID: PMC3834197.
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Validity of self-reported adult secondhand smoke exposure. Tob Control. 2015 Jan; 24(1):48-53. Prochaska JJ, Grossman W, Young-Wolff KC, Benowitz NL. PMID: 23997071; PMCID: PMC4458852.
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Cytisine, the world's oldest smoking cessation aid. BMJ. 2013 Aug 23; 347:f5198. Prochaska JJ, Das S, Benowitz NL. PMID: 23974638.
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The regulatory challenge of electronic cigarettes. JAMA. 2013 Aug 21; 310(7):685-6. Benowitz NL, Goniewicz ML. PMID: 23856948.
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Genetic and pharmacokinetic determinants of response to transdermal nicotine in white, black, and Asian nonsmokers. Clin Pharmacol Ther. 2013 Dec; 94(6):687-94. Dempsey DA, St Helen G, Jacob P, Tyndale RF, Benowitz NL. PMID: 23933970; PMCID: PMC3834081.
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Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake. PLoS One. 2013; 8(8):e70938. Zhu AZ, Zhou Q, Cox LS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 23936477; PMCID: PMC3732272.
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CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users. Addiction. 2013 Oct; 108(10):1818-28. Zhu AZ, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF. PMID: 23692359; PMCID: PMC3775934.
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CYP2A6 genotype but not age determines cotinine half-life in infants and children. Clin Pharmacol Ther. 2013 Sep; 94(3):400-6. Dempsey DA, Sambol NC, Jacob P, Hoffmann E, Tyndale RF, Fuentes-Afflick E, Benowitz NL. PMID: 23714690; PMCID: PMC3820275.
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Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes. Nicotine Tob Res. 2013 Nov; 15(11):1939-42. St Helen G, Jacob P, Benowitz NL. PMID: 23674838; PMCID: PMC3790625.
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Reducing the nicotine content to make cigarettes less addictive. Tob Control. 2013 May; 22 Suppl 1:i14-7. Benowitz NL, Henningfield JE. PMID: 23591498; PMCID: PMC3632983.
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Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control. 2014 Mar; 23(2):133-9. Goniewicz ML, Knysak J, Gawron M, Kosmider L, Sobczak A, Kurek J, Prokopowicz A, Jablonska-Czapla M, Rosik-Dulewska C, Havel C, Jacob P, Benowitz N. PMID: 23467656; PMCID: PMC4154473.
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Comparison of nicotine and carcinogen exposure with water pipe and cigarette smoking. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):765-72. Jacob P, Abu Raddaha AH, Dempsey D, Havel C, Peng M, Yu L, Benowitz NL. PMID: 23462922; PMCID: PMC3650103.
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Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state. Pharmacogenet Genomics. 2013 Mar; 23(3):135-41. Benowitz NL, Zhu AZ, Tyndale RF, Dempsey D, Jacob P. PMID: 23344581; PMCID: PMC3763712.
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Smoking cessation after acute myocardial infarction. J Am Coll Cardiol. 2013 Feb 05; 61(5):533-5. Benowitz NL, Prochaska JJ. PMID: 23369418.
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Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. Pharmacogenet Genomics. 2013 Feb; 23(2):94-103. Bergen AW, Javitz HS, Krasnow R, Nishita D, Michel M, Conti DV, Liu J, Lee W, Edlund CK, Hall S, Kwok PY, Benowitz NL, Baker TB, Tyndale RF, Lerman C, Swan GE. PMID: 23249876; PMCID: PMC3563676.
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The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):708-18. Zhu AZ, Renner CC, Hatsukami DK, Swan GE, Lerman C, Benowitz NL, Tyndale RF. PMID: 23371292; PMCID: PMC3617060.
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Biomarkers of secondhand smoke exposure in automobiles. Tob Control. 2014 Jan; 23(1):51-7. Jones IA, St Helen G, Meyers MJ, Dempsey DA, Havel C, Jacob P, Northcross A, Hammond SK, Benowitz NL. PMID: 23349229; PMCID: PMC3670969.
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Dose-independent kinetics with low level exposure to nicotine and cotinine. Br J Clin Pharmacol. 2013 Jan; 75(1):277-9. Benowitz NL, Dempsey D, Tyndale RF, St Helen G, Jacob P. PMID: 22574797; PMCID: PMC3555070.
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Race, gender, and nicotine metabolism in adolescent smokers. Nicotine Tob Res. 2013 Jul; 15(7):1311-5. Rubinstein ML, Shiffman S, Rait MA, Benowitz NL. PMID: 23239845; PMCID: PMC3682846.
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The DRD4 exon III VNTR, bupropion, and associations with prospective abstinence. Nicotine Tob Res. 2013 Jul; 15(7):1190-200. Bergen AW, Javitz HS, Su L, He Y, Conti DV, Benowitz NL, Tyndale RF, Lerman C, Swan GE. PMID: 23212438; PMCID: PMC3682839.
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Predictors of cessation in African American light smokers enrolled in a bupropion clinical trial. Addict Behav. 2013 Mar; 38(3):1796-803. Faseru B, Nollen NL, Mayo MS, Krebill R, Choi WS, Benowitz NL, Tyndale RF, Okuyemi KS, Ahluwalia JS, Sanderson Cox L. PMID: 23254230; PMCID: PMC3558614.
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Particulate mass and polycyclic aromatic hydrocarbons exposure from secondhand smoke in the back seat of a vehicle. Tob Control. 2014 Jan; 23(1):14-20. Northcross AL, Trinh M, Kim J, Jones IA, Meyers MJ, Dempsey DD, Benowitz NL, Hammond SK. PMID: 23172398.
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CYP2B6 and bupropion's smoking-cessation pharmacology: the role of hydroxybupropion. Clin Pharmacol Ther. 2012 Dec; 92(6):771-7. Zhu AZ, Cox LS, Nollen N, Faseru B, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 23149928; PMCID: PMC3729209.
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Air quality, mortality, and economic benefits of a smoke - free workplace law for non-smoking Ontario bar workers. Indoor Air. 2013 Apr; 23(2):93-104. Repace J, Zhang B, Bondy SJ, Benowitz N, Ferrence R. PMID: 23006034.
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Racial differences in the relationship between tobacco dependence and nicotine and carcinogen exposure. Addiction. 2013 Mar; 108(3):607-17. St Helen G, Dempsey D, Wilson M, Jacob P, Benowitz NL. PMID: 22971134; PMCID: PMC3553231.
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Nicotine reduction: strategic research plan. Nicotine Tob Res. 2013 Jun; 15(6):1003-13. Hatsukami DK, Benowitz NL, Donny E, Henningfield J, Zeller M. PMID: 23100460; PMCID: PMC3646645.
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Correlates of NNAL levels among nondaily and daily smokers in the college student population. Curr Biomark Find. 2012 Oct 15; 2012(2). Berg CJ, Schauer GL, Ahluwalia JS, Benowitz NL. PMID: 24298447; PMCID: PMC3843970.
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Nicotine metabolism and addiction among adolescent smokers. Addiction. 2013 Feb; 108(2):406-12. Rubinstein ML, Shiffman S, Moscicki AB, Rait MA, Sen S, Benowitz NL. PMID: 22823143; PMCID: PMC3504133.
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Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation. Carcinogenesis. 2013 Jan; 34(1):93-101. Zhu AZ, Binnington MJ, Renner CC, Lanier AP, Hatsukami DK, Stepanov I, Watson CH, Sosnoff CS, Benowitz NL, Tyndale RF. PMID: 23027621; PMCID: PMC3534190.
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Tobacco use among southwestern Alaska Native people. Nicotine Tob Res. 2013 Feb; 15(2):401-6. Renner CC, Lanier AP, Lindgren B, Jensen J, Patten CA, Parascandola M, Benowitz NL, Tyndale RF, Hatsukami DK. PMID: 22949573; PMCID: PMC3612002.
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Assessing secondhand smoke using biological markers. Tob Control. 2013 May; 22(3):164-71. Avila-Tang E, Al-Delaimy WK, Ashley DL, Benowitz N, Bernert JT, Kim S, Samet JM, Hecht SS. PMID: 22940677; PMCID: PMC3639350.
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Determination of tobacco smoke exposure by plasma cotinine levels in infants and children attending urban public hospital clinics. Arch Pediatr Adolesc Med. 2012 Sep 01; 166(9):851-6. Dempsey DA, Meyers MJ, Oh SS, Nguyen EA, Fuentes-Afflick E, Wu AH, Jacob P, Benowitz NL. PMID: 22566513; PMCID: PMC3997061.
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Nicotine intake and smoking topography in smokers with bipolar disorder. Bipolar Disord. 2012 Sep; 14(6):618-27. Williams JM, Gandhi KK, Lu SE, Steinberg ML, Benowitz NL. PMID: 22938167; PMCID: PMC3641517.
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Very low nicotine content cigarettes and potential consequences on cardiovascular disease. Curr Cardiovasc Risk Rep. 2012 Dec 01; 6(6):534-541. Joel DL, Denlinger RL, Dermody SS, Hatsukami DK, Benowitz NL, Donny EC. PMID: 23264843; PMCID: PMC3525710.
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Population approaches to improve diet, physical activity, and smoking habits: a scientific statement from the American Heart Association. Circulation. 2012 Sep 18; 126(12):1514-63. Mozaffarian D, Afshin A, Benowitz NL, Bittner V, Daniels SR, Franch HA, Jacobs DR, Kraus WE, Kris-Etherton PM, Krummel DA, Popkin BM, Whitsel LP, Zakai NA, American Heart Association Council on Epidemiology and Prevention, Council on Nutrition, Physical Ac. PMID: 22907934; PMCID: PMC3881293.
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DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers. Pharmacogenet Genomics. 2012 Jul; 22(7):551-4. Lee W, Ray R, Bergen AW, Swan GE, Thomas P, Tyndale RF, Benowitz NL, Lerman C, Conti DV. PMID: 22495174; PMCID: PMC3376177.
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CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people. Pharmacogenet Genomics. 2012 Jun; 22(6):429-40. Binnington MJ, Zhu AZ, Renner CC, Lanier AP, Hatsukami DK, Benowitz NL, Tyndale RF. PMID: 22569203; PMCID: PMC3349071.
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High dose transdermal nicotine for fast metabolizers of nicotine: a proof of concept placebo-controlled trial. Nicotine Tob Res. 2013 Feb; 15(2):348-54. Schnoll RA, Wileyto EP, Leone FT, Tyndale RF, Benowitz NL. PMID: 22589423; PMCID: PMC3545715.
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Reproducibility of the nicotine metabolite ratio in cigarette smokers. Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7):1105-14. St Helen G, Novalen M, Heitjan DF, Dempsey D, Jacob P, Aziziyeh A, Wing VC, George TP, Tyndale RF, Benowitz NL. PMID: 22552800; PMCID: PMC3392523.
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Exposure to nicotine and carcinogens among Southwestern Alaskan Native cigarette smokers and smokeless tobacco users. Cancer Epidemiol Biomarkers Prev. 2012 Jun; 21(6):934-42. Benowitz NL, Renner CC, Lanier AP, Tyndale RF, Hatsukami DK, Lindgren B, Stepanov I, Watson CH, Sosnoff CS, Jacob P. PMID: 22490317; PMCID: PMC3444141.
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Exposure and kinetics of polycyclic aromatic hydrocarbons (PAHs) in cigarette smokers. Chem Res Toxicol. 2012 Apr 16; 25(4):952-64. St Helen G, Goniewicz ML, Dempsey D, Wilson M, Jacob P, Benowitz NL. PMID: 22428611; PMCID: PMC3330130.
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Adherence to varenicline among African American smokers: an exploratory analysis comparing plasma concentration, pill count, and self-report. Nicotine Tob Res. 2012 Sep; 14(9):1083-91. Buchanan TS, Berg CJ, Cox LS, Nazir N, Benowitz NL, Yu L, Yturralde O, Jacob P, Choi WS, Ahluwalia JS, Nollen NL. PMID: 22367976; PMCID: PMC3432278.
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Smoking behavior and exposure to tobacco toxicants during 6 months of smoking progressively reduced nicotine content cigarettes. Cancer Epidemiol Biomarkers Prev. 2012 May; 21(5):761-9. Benowitz NL, Dains KM, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P. PMID: 22354905; PMCID: PMC3348427.
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Effects of menthol on the pharmacokinetics of bupropion among Black smokers. Nicotine Tob Res. 2012 Jun; 14(6):688-93. Okuyemi KS, Faseru B, Reed GA, Cox LS, Bronars CA, Opole I, Whembolua GL, Mayo MS, Ahluwalia JS, Benowitz NL. PMID: 22318754; PMCID: PMC3356293.
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Rapid smoking may not be aversive in schizophrenia. Nicotine Tob Res. 2013 Jan; 15(1):262-6. Williams JM, Gandhi KK, Lu SE, Steinberg ML, Benowitz NL. PMID: 22318691; PMCID: PMC3524052.
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Bupropion for smoking cessation in African American light smokers: a randomized controlled trial. J Natl Cancer Inst. 2012 Feb 22; 104(4):290-8. Cox LS, Nollen NL, Mayo MS, Choi WS, Faseru B, Benowitz NL, Tyndale RF, Okuyemi KS, Ahluwalia JS. PMID: 22282543; PMCID: PMC3283533.
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Chronic disease management approach to treating tobacco addiction: comment on "Nicotine therapy sampling to induce quit attempts among smokers unmotivated to quit". Arch Intern Med. 2011 Nov 28; 171(21):1907-9. Benowitz NL. PMID: 22123797.
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Gene-centric analysis of serum cotinine levels in African and European American populations. Neuropsychopharmacology. 2012 Mar; 37(4):968-74. Hamidovic A, Goodloe RJ, Bergen AW, Benowitz NL, Styn MA, Kasberger JL, Choquet H, Young TR, Meng Y, Palmer C, Pletcher M, Kertesz S, Hitsman B, Spring B, Jorgenson E. PMID: 22089314; PMCID: PMC3280653.
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Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials. Neuropsychopharmacology. 2012 Feb; 37(3):641-50. King DP, Paciga S, Pickering E, Benowitz NL, Bierut LJ, Conti DV, Kaprio J, Lerman C, Park PW. PMID: 22048466; PMCID: PMC3260990.
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Effect of nicotine on cytochrome P450 1A2 activity. Br J Clin Pharmacol. 2011 Nov; 72(5):836-8. Hukkanen J, Jacob P, Peng M, Dempsey D, Benowitz NL. PMID: 21599724; PMCID: PMC3243019.
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Cardiology Rx for Change: improving clinical attention to tobacco use and secondhand smoke exposure in cardiology. Clin Cardiol. 2011 Dec; 34(12):738-43. Prochaska JJ, Benowitz NL, Glantz SA, Hudmon KS, Grossman W. PMID: 21987417; PMCID: PMC6652489.
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Nicotine, carbon monoxide, and carcinogen exposure after a single use of a water pipe. Cancer Epidemiol Biomarkers Prev. 2011 Nov; 20(11):2345-53. Jacob P, Abu Raddaha AH, Dempsey D, Havel C, Peng M, Yu L, Benowitz NL. PMID: 21908725; PMCID: PMC3210932.
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Sodium oxybate: updates and correction to previously published safety data. J Clin Sleep Med. 2011 Aug 15; 7(4):415-6. Wang YG, Swick TJ, Carter LP, Thorpy MJ, Benowitz NL. PMID: 21897784; PMCID: PMC3161779.
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Smokeless tobacco as a nicotine delivery device: harm or harm reduction? Clin Pharmacol Ther. 2011 Oct; 90(4):491-3. Benowitz NL. PMID: 21934719.
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Gender-stratified gene and gene-treatment interactions in smoking cessation. Pharmacogenomics J. 2012 Dec; 12(6):521-32. Lee W, Bergen AW, Swan GE, Li D, Liu J, Thomas P, Tyndale RF, Benowitz NL, Lerman C, Conti DV. PMID: 21808284; PMCID: PMC3208134.
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Cigarette smoking, nicotine, and body weight. Clin Pharmacol Ther. 2011 Jul; 90(1):164-8. Audrain-McGovern J, Benowitz NL. PMID: 21633341; PMCID: PMC3195407.
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Thirdhand tobacco smoke: emerging evidence and arguments for a multidisciplinary research agenda. Environ Health Perspect. 2011 Sep; 119(9):1218-26. Matt GE, Quintana PJ, Destaillats H, Gundel LA, Sleiman M, Singer BC, Jacob P, Benowitz N, Winickoff JP, Rehan V, Talbot P, Schick S, Samet J, Wang Y, Hang B, Martins-Green M, Pankow JF, Hovell MF. PMID: 21628107; PMCID: PMC3230406.
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Shorter interpuff interval is associated with higher nicotine intake in smokers with schizophrenia. Drug Alcohol Depend. 2011 Nov 01; 118(2-3):313-9. Williams JM, Gandhi KK, Lu SE, Kumar S, Steinberg ML, Cottler B, Benowitz NL. PMID: 21596491; PMCID: PMC3655704.
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Racial differences in the relationship between number of cigarettes smoked and nicotine and carcinogen exposure. Nicotine Tob Res. 2011 Sep; 13(9):772-83. Benowitz NL, Dains KM, Dempsey D, Wilson M, Jacob P. PMID: 21546441; PMCID: PMC3168241.
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The threat of menthol cigarettes to U.S. public health. N Engl J Med. 2011 Jun 09; 364(23):2179-81. Benowitz NL, Samet JM. PMID: 21542737.
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Do biological differences help explain tobacco-related disparities? Am J Health Promot. 2011 May-Jun; 25(5 Suppl):S8-10. Pérez-Stable EJ, Benowitz NL. PMID: 21510792.
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Attitudes and practices of hookah smokers in the San Francisco Bay Area. J Psychoactive Drugs. 2011 Apr-Jun; 43(2):146-52. Ahmed B, Jacob P, Allen F, Benowitz N. PMID: 21858960.
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Genetic variability of smoking persistence in African Americans. Cancer Prev Res (Phila). 2011 May; 4(5):729-34. Hamidovic A, Kasberger JL, Young TR, Goodloe RJ, Redline S, Buxbaum SG, Benowitz NL, Bergen AW, Butler KR, Franceschini N, Gharib SA, Hitsman B, Levy D, Meng Y, Papanicolaou GJ, Preis SR, Spring B, Styn MA, Tong EK, White WB, Wiggins KL, Jorgenson E. PMID: 21436384; PMCID: PMC3095514.
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Active and passive cigarette smoking and acute lung injury after severe blunt trauma. Am J Respir Crit Care Med. 2011 Jun 15; 183(12):1660-5. Calfee CS, Matthay MA, Eisner MD, Benowitz N, Call M, Pittet JF, Cohen MJ. PMID: 21471091; PMCID: PMC3136993.
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Association of the nicotine metabolite ratio and CHRNA5/CHRNA3 polymorphisms with smoking rate among treatment-seeking smokers. Nicotine Tob Res. 2011 Jun; 13(6):498-503. Falcone M, Jepson C, Benowitz N, Bergen AW, Pinto A, Wileyto EP, Baldwin D, Tyndale RF, Lerman C, Ray R. PMID: 21385908; PMCID: PMC3103715.
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Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data. Trials. 2011 Jan 25; 12:22. Cox LS, Faseru B, Mayo MS, Krebill R, Snow TS, Bronars CA, Nollen NL, Choi WS, Okuyemi KS, Salzman GA, Benowitz NL, Tyndale RF, Ahluwalia JS. PMID: 21266057; PMCID: PMC3038942.
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Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate active from passive smoking. Nicotine Tob Res. 2011 Mar; 13(3):202-8. Goniewicz ML, Eisner MD, Lazcano-Ponce E, Zielinska-Danch W, Koszowski B, Sobczak A, Havel C, Jacob P, Benowitz NL. PMID: 21330276; PMCID: PMC3045466.
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Treatment of nicotine addiction: present therapeutic options and pipeline developments. Trends Pharmacol Sci. 2011 May; 32(5):281-9. Polosa R, Benowitz NL. PMID: 21256603; PMCID: PMC5564372.
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Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level. Cancer Epidemiol Biomarkers Prev. 2011 Feb; 20(2):234-8. Strasser AA, Benowitz NL, Pinto AG, Tang KZ, Hecht SS, Carmella SG, Tyndale RF, Lerman CE. PMID: 21212060; PMCID: PMC3077576.
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Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients. Crit Care Med. 2011 Jan; 39(1):40-5. Hsieh SJ, Ware LB, Eisner MD, Yu L, Jacob P, Havel C, Goniewicz ML, Matthay MA, Benowitz NL, Calfee CS. PMID: 20935560; PMCID: PMC3148017.
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Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome P450 2A6 activity. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Feb 01; 879(3-4):267-76. Jacob P, Yu L, Duan M, Ramos L, Yturralde O, Benowitz NL. PMID: 21208832; PMCID: PMC3050598.
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Cautions and warnings on the US OTC label for nicotine replacement: what's a doctor to do? Addict Behav. 2011 Apr; 36(4):327-32. Zapawa LM, Hughes JR, Benowitz NL, Rigotti NA, Shiffman S. PMID: 21220188.
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Impact of smoking on cardiovascular events in patients with coronary disease receiving contemporary medical therapy (from the Treating to New Targets [TNT] and the Incremental Decrease in End Points Through Aggressive Lipid Lowering [IDEAL] trials). Am J Cardiol. 2011 Jan 15; 107(2):145-50. Frey P, Waters DD, DeMicco DA, Breazna A, Samuels L, Pipe A, Wun CC, Benowitz NL. PMID: 21129718.
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Urine menthol as a biomarker of mentholated cigarette smoking. Cancer Epidemiol Biomarkers Prev. 2010 Dec; 19(12):3013-9. Benowitz NL, Dains KM, Dempsey D, Havel C, Wilson M, Jacob P. PMID: 20962297; PMCID: PMC3005539.
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Nicotine reduction revisited: science and future directions. Tob Control. 2010 Oct; 19(5):e1-10. Hatsukami DK, Perkins KA, Lesage MG, Ashley DL, Henningfield JE, Benowitz NL, Backinger CL, Zeller M. PMID: 20876072; PMCID: PMC4618689.
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Impact of smokeless tobacco products on cardiovascular disease: implications for policy, prevention, and treatment: a policy statement from the American Heart Association. Circulation. 2010 Oct 12; 122(15):1520-44. Piano MR, Benowitz NL, Fitzgerald GA, Corbridge S, Heath J, Hahn E, Pechacek TF, Howard G, American Heart Association Council on Cardiovascular Nursing. PMID: 20837898.
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Urine cotinine underestimates exposure to the tobacco-derived lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in passive compared with active smokers. Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2795-800. Benowitz N, Goniewicz ML, Eisner MD, Lazcano-Ponce E, Zielinska-Danch W, Koszowski B, Sobczak A, Havel C, Jacob P. PMID: 20805316; PMCID: PMC2976834.
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Carbamazepine but not valproate induces CYP2A6 activity in smokers with mental illness. Cancer Epidemiol Biomarkers Prev. 2010 Oct; 19(10):2582-9. Williams JM, Gandhi KK, Benowitz NL. PMID: 20719908; PMCID: PMC2952059.
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Nicotine deprivation and pilot performance during simulated flight. Aviat Space Environ Med. 2010 Jul; 81(7):660-4. Mumenthaler MS, Benowitz NL, Taylor JL, Friedman L, Noda A, Yesavage JA. PMID: 20597245.
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Environmental and biological monitoring of exposures to PAHs and ETS in the general population. Environ Int. 2010 Oct; 36(7):763-71. Aquilina NJ, Delgado-Saborit JM, Meddings C, Baker S, Harrison RM, Jacob P, Wilson M, Yu L, Duan M, Benowitz NL. PMID: 20591483; PMCID: PMC3148021.
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Higher nicotine levels in schizophrenia compared with controls after smoking a single cigarette. Nicotine Tob Res. 2010 Aug; 12(8):855-9. Williams JM, Gandhi KK, Lu SE, Kumar S, Shen J, Foulds J, Kipen H, Benowitz NL. PMID: 20584771; PMCID: PMC2910875.
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Nicotine addiction. N Engl J Med. 2010 Jun 17; 362(24):2295-303. Benowitz NL. PMID: 20554984; PMCID: PMC2928221.
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Chinese 'low-tar' cigarettes do not deliver lower levels of nicotine and carcinogens. Tob Control. 2010 Oct; 19(5):374-9. Gan Q, Lu W, Xu J, Li X, Goniewicz M, Benowitz NL, Glantz SA. PMID: 20507920; PMCID: PMC2978929.
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Estimation of nicotine dose after low-level exposure using plasma and urine nicotine metabolites. Cancer Epidemiol Biomarkers Prev. 2010 May; 19(5):1160-6. Benowitz NL, Dains KM, Dempsey D, Yu L, Jacob P. PMID: 20447913; PMCID: PMC2867075.
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What is the role of lidocaine or phenytoin in tricyclic antidepressant-induced cardiotoxicity? Clin Toxicol (Phila). 2010 May; 48(4):325-30. Foianini A, Joseph Wiegand T, Benowitz N. PMID: 20507243.
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Genetic variation in nicotine metabolism predicts the efficacy of extended-duration transdermal nicotine therapy. Clin Pharmacol Ther. 2010 May; 87(5):553-7. Lerman C, Jepson C, Wileyto EP, Patterson F, Schnoll R, Mroziewicz M, Benowitz N, Tyndale RF. PMID: 20336063; PMCID: PMC3896974.
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Higher serum caffeine in smokers with schizophrenia compared to smoking controls. Drug Alcohol Depend. 2010 Jul 01; 110(1-2):151-5. Gandhi KK, Williams JM, Menza M, Galazyn M, Benowitz NL. PMID: 20227198; PMCID: PMC2885547.
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Varenicline and pheochromocytoma. Ann Intern Med. 2010 Mar 02; 152(5):335-6. Hukkanen J, Ukkola O, Benowitz NL. PMID: 20194248.
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Secondhand smoke and infectious disease in adults: A global women's health concern: Comment on "Passive Smoking and Tuberculosis". Arch Intern Med. 2010 Feb 08; 170(3):292-3. Benowitz NL. PMID: 20142577.
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New CYP2A6 gene deletion and conversion variants in a population of Black African descent. Pharmacogenomics. 2010 Feb; 11(2):189-98. Mwenifumbo JC, Zhou Q, Benowitz NL, Sellers EM, Tyndale RF. PMID: 20136358; PMCID: PMC2922202.
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Effects of nicotine on cytochrome P450 2A6 and 2E1 activities. Br J Clin Pharmacol. 2010 Feb; 69(2):152-9. Hukkanen J, Jacob Iii P, Peng M, Dempsey D, Benowitz NL. PMID: 20233178; PMCID: PMC2824476.
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Efficacy and safety of varenicline for smoking cessation in patients with cardiovascular disease: a randomized trial. Circulation. 2010 Jan 19; 121(2):221-9. Rigotti NA, Pipe AL, Benowitz NL, Arteaga C, Garza D, Tonstad S. PMID: 20048210; PMCID: PMC4096941.
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Elimination kinetics of the tobacco-specific biomarker and lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Cancer Epidemiol Biomarkers Prev. 2009 Dec; 18(12):3421-5. Goniewicz ML, Havel CM, Peng MW, Jacob P, Dempsey D, Yu L, Zielinska-Danch W, Koszowski B, Czogala J, Sobczak A, Benowitz NL. PMID: 19959691; PMCID: PMC2804843.
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Utility and relationships of biomarkers of smoking in African-American light smokers. Cancer Epidemiol Biomarkers Prev. 2009 Dec; 18(12):3426-34. Ho MK, Faseru B, Choi WS, Nollen NL, Mayo MS, Thomas JL, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 19959692; PMCID: PMC2791893.
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Chinese "herbal" cigarettes are as carcinogenic and addictive as regular cigarettes. Cancer Epidemiol Biomarkers Prev. 2009 Dec; 18(12):3497-501. Gan Q, Yang J, Yang G, Goniewicz M, Benowitz NL, Glantz SA. PMID: 19959701; PMCID: PMC2789338.
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Interlaboratory comparability of serum cotinine measurements at smoker and nonsmoker concentration levels: a round-robin study. Nicotine Tob Res. 2009 Dec; 11(12):1458-66. Bernert JT, Jacob P, Holiday DB, Benowitz NL, Sosnoff CS, Doig MV, Feyerabend C, Aldous KM, Sharifi M, Kellogg MD, Langman LJ. PMID: 19933777; PMCID: PMC3167685.
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Counseling to reduce children's secondhand smoke exposure and help parents quit smoking: a controlled trial. Nicotine Tob Res. 2009 Dec; 11(12):1383-94. Hovell MF, Zakarian JM, Matt GE, Liles S, Jones JA, Hofstetter CR, Larson SN, Benowitz NL. PMID: 19875762; PMCID: PMC2784487.
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Genetic influences on individual differences in nicotine glucuronidation. Twin Res Hum Genet. 2009 Oct; 12(5):507-13. Lessov-Schlaggar CN, Benowitz NL, Jacob P, Swan GE. PMID: 19803778; PMCID: PMC3202423.
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Prevalence of smoking assessed biochemically in an urban public hospital: a rationale for routine cotinine screening. Am J Epidemiol. 2009 Oct 01; 170(7):885-91. Benowitz NL, Schultz KE, Haller CA, Wu AH, Dains KM, Jacob P. PMID: 19713287; PMCID: PMC2765360.
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Safety overview of postmarketing and clinical experience of sodium oxybate (Xyrem): abuse, misuse, dependence, and diversion. J Clin Sleep Med. 2009 Aug 15; 5(4):365-71. Wang YG, Swick TJ, Carter LP, Thorpy MJ, Benowitz NL. PMID: 19968016; PMCID: PMC2725257.
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Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Nicotine Tob Res. 2009 Aug; 11(8):945-53. Eisner MD, Jacob P, Benowitz NL, Balmes J, Blanc PD. PMID: 19587064; PMCID: PMC2711983.
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A systems biology network model for genetic association studies of nicotine addiction and treatment. Pharmacogenet Genomics. 2009 Jul; 19(7):538-51. Thomas PD, Mi H, Swan GE, Lerman C, Benowitz N, Tyndale RF, Bergen AW, Conti DV, Pharmacogenetics of Nicotine Addiction and Treatment Consortium. PMID: 19525886; PMCID: PMC6485245.
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Urine nicotine metabolite concentrations in relation to plasma cotinine during low-level nicotine exposure. Nicotine Tob Res. 2009 Aug; 11(8):954-60. Benowitz NL, Dains KM, Dempsey D, Herrera B, Yu L, Jacob P. PMID: 19525206; PMCID: PMC2734286.
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Genome-wide linkage of cotinine pharmacokinetics suggests candidate regions on chromosomes 9 and 11. Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 05; 150B(4):554-9. He Y, Bergen AW, Hops H, Andrews JA, Tildesley E, Lessov-Schlaggar CN, Webster C, Benowitz N, Swan GE. PMID: 18785207; PMCID: PMC2693302.
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Calibrating self-reported measures of maternal smoking in pregnancy via bioassays using a Monte Carlo approach. Int J Environ Res Public Health. 2009 06; 6(6):1744-59. Dukic VM, Niessner M, Pickett KE, Benowitz NL, Wakschlag LS. PMID: 19578458; PMCID: PMC2705215.
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Dopamine genes and nicotine dependence in treatment-seeking and community smokers. Neuropsychopharmacology. 2009 Sep; 34(10):2252-64. Bergen AW, Conti DV, Van Den Berg D, Lee W, Liu J, Li D, Guo N, Mi H, Thomas PD, Lessov-Schlaggar CN, Krasnow R, He Y, Nishita D, Jiang R, McClure JB, Tildesley E, Hops H, Tyndale RF, Benowitz NL, Lerman C, Swan GE. PMID: 19494806; PMCID: PMC3558036.
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Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine. Pharmacogenet Genomics. 2009 May; 19(5):388-98. Swan GE, Lessov-Schlaggar CN, Bergen AW, He Y, Tyndale RF, Benowitz NL. PMID: 19300303; PMCID: PMC2849278.
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Impact of an indoor smoking ban on bar workers' exposure to secondhand smoke. J Occup Environ Med. 2009 May; 51(5):612-9. Bondy SJ, Zhang B, Kreiger N, Selby P, Benowitz N, Travis H, Florescu A, Greenspan NR, Ferrence R. PMID: 19369895.
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Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers. Clin Pharmacol Ther. 2009 Jun; 85(6):635-43. Ho MK, Mwenifumbo JC, Al Koudsi N, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 19279561; PMCID: PMC3698861.
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Progressive commercial cigarette yield reduction: biochemical exposure and behavioral assessment. Cancer Epidemiol Biomarkers Prev. 2009 Mar; 18(3):876-83. Benowitz NL, Dains KM, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P. PMID: 19258480; PMCID: PMC2802575.
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Withdrawal in adolescent light smokers following 24-hour abstinence. Nicotine Tob Res. 2009 Feb; 11(2):185-9. Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. PMID: 19246428; PMCID: PMC2658900.
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Nicotine chemistry, metabolism, kinetics and biomarkers. Handb Exp Pharmacol. 2009; (192):29-60. Benowitz NL, Hukkanen J, Jacob P. PMID: 19184645; PMCID: PMC2953858.
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Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics. Annu Rev Pharmacol Toxicol. 2009; 49:57-71. Benowitz NL. PMID: 18834313; PMCID: PMC2946180.
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Optimal serum cotinine levels for distinguishing cigarette smokers and nonsmokers within different racial/ethnic groups in the United States between 1999 and 2004. Am J Epidemiol. 2009 Jan 15; 169(2):236-48. Benowitz NL, Bernert JT, Caraballo RS, Holiday DB, Wang J. PMID: 19019851.
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Nicotine metabolic rate predicts successful smoking cessation with transdermal nicotine: a validation study. Pharmacol Biochem Behav. 2009 Mar; 92(1):6-11. Schnoll RA, Patterson F, Wileyto EP, Tyndale RF, Benowitz N, Lerman C. PMID: 19000709; PMCID: PMC2657225.
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Subpicogram per milliliter determination of the tobacco-specific carcinogen metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine using liquid chromatography-tandem mass spectrometry. Anal Chem. 2008 Nov 01; 80(21):8115-21. Jacob P, Havel C, Lee DH, Yu L, Eisner MD, Benowitz NL. PMID: 18841944; PMCID: PMC3167662.
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Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers. Behav Pharmacol. 2008 Sep; 19(5-6):630-40. Perkins KA, Lerman C, Coddington S, Jetton C, Karelitz JL, Wilson A, Jennings JR, Ferrell R, Bergen AW, Benowitz NL. PMID: 18690117; PMCID: PMC2743299.
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Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. Behav Pharmacol. 2008 Sep; 19(5-6):641-9. Perkins KA, Lerman C, Grottenthaler A, Ciccocioppo MM, Milanak M, Conklin CA, Bergen AW, Benowitz NL. PMID: 18690118; PMCID: PMC2717609.
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A randomized trial of nicotine nasal spray in adolescent smokers. Pediatrics. 2008 Sep; 122(3):e595-600. Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. PMID: 18762494; PMCID: PMC2744418.
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Smoking behavior in men hospitalized with cardiovascular disease in Korea: a cross-sectional descriptive study. Heart Lung. 2008 Sep-Oct; 37(5):366-79. Sohn M, Benowitz N, Stotts N, Christopherson D, Kim KS, Jang YS, Ahn MS, Froelicher ES. PMID: 18790337.
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Nicotine and postoperative management of pain. Anesth Analg. 2008 Sep; 107(3):739-41. Benowitz NL. PMID: 18713874.
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Rate of nicotine metabolism and withdrawal symptoms in adolescent light smokers. Pediatrics. 2008 Sep; 122(3):e643-7. Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. PMID: 18762498; PMCID: PMC2722964.
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Nicotine metabolism in pregnant and nonpregnant rabbits. Nicotine Tob Res. 2008 Aug; 10(8):1385-90. Tutka P, Dempsey DA, Jacob P, Benowitz NL, Kroetz DL. PMID: 18686186; PMCID: PMC2923225.
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Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst. 2008 Aug 06; 100(15):1104-12. Xing J, Chen M, Wood CG, Lin J, Spitz MR, Ma J, Amos CI, Shields PG, Benowitz NL, Gu J, de Andrade M, Swan GE, Wu X. PMID: 18664653; PMCID: PMC2720693.
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Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. Hum Mol Genet. 2008 Sep 15; 17(18):2834-48. Conti DV, Lee W, Li D, Liu J, Van Den Berg D, Thomas PD, Bergen AW, Swan GE, Tyndale RF, Benowitz NL, Lerman C, Pharmacogenetics of Nicotine Addiction and Treatment Consortium. PMID: 18593715; PMCID: PMC2525499.
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Creating and evaluating genetic tests predictive of drug response. Nat Rev Drug Discov. 2008 07; 7(7):568-74. Weiss ST, McLeod HL, Flockhart DA, Dolan ME, Benowitz NL, Johnson JA, Ratain MJ, Giacomini KM. PMID: 18587383; PMCID: PMC2682785.
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Dietary supplement adverse events: report of a one-year poison center surveillance project. J Med Toxicol. 2008 Jun; 4(2):84-92. Haller C, Kearney T, Bent S, Ko R, Benowitz N, Olson K. PMID: 18570167; PMCID: PMC3550135.
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Assessing dimensions of nicotine dependence: an evaluation of the Nicotine Dependence Syndrome Scale (NDSS) and the Wisconsin Inventory of Smoking Dependence Motives (WISDM). Nicotine Tob Res. 2008 Jun; 10(6):1009-20. Piper ME, McCarthy DE, Bolt DM, Smith SS, Lerman C, Benowitz N, Fiore MC, Baker TB. PMID: 18584464; PMCID: PMC2614360.
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Chocolate consumption in pregnancy and reduced likelihood of preeclampsia. Epidemiology. 2008 May; 19(3):459-64. Triche EW, Grosso LM, Belanger K, Darefsky AS, Benowitz NL, Bracken MB. PMID: 18379424; PMCID: PMC2782959.
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Toward personalized therapy for smoking cessation: a randomized placebo-controlled trial of bupropion. Clin Pharmacol Ther. 2008 Sep; 84(3):320-5. Patterson F, Schnoll RA, Wileyto EP, Pinto A, Epstein LH, Shields PG, Hawk LW, Tyndale RF, Benowitz N, Lerman C. PMID: 18388868.
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Genetic influences in the variation in renal clearance of nicotine and cotinine. Clin Pharmacol Ther. 2008 Aug; 84(2):243-7. Benowitz NL, Lessov-Schlaggar CN, Swan GE. PMID: 18388871.
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Neurobiology of nicotine addiction: implications for smoking cessation treatment. Am J Med. 2008 Apr; 121(4 Suppl 1):S3-10. Benowitz NL. PMID: 18342164.
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Human pharmacology of a performance-enhancing dietary supplement under resting and exercise conditions. Br J Clin Pharmacol. 2008 Jun; 65(6):833-40. Haller CA, Duan M, Jacob P, Benowitz N. PMID: 18341680; PMCID: PMC2485232.
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Prenatal caffeine assessment: fetal and maternal biomarkers or self-reported intake? Ann Epidemiol. 2008 Mar; 18(3):172-8. Grosso LM, Triche E, Benowitz NL, Bracken MB. PMID: 18083538; PMCID: PMC2275917.
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Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction. Clin Pharmacol Ther. 2008 Apr; 83(4):531-41. Benowitz NL. PMID: 18305452.
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Determinants of salivary cotinine level: a population-based study in Brazil. Rev Saude Publica. 2007 Dec; 41(6):954-62. Figueiredo VC, Szklo M, Szklo AS, Benowitz N, Lozana JA, Casado L, Masson E, Samet J. PMID: 17992352.
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Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism. Pharmacogenet Genomics. 2007 Dec; 17(12):1007-15. Ring HZ, Valdes AM, Nishita DM, Prasad S, Jacob P, Tyndale RF, Swan GE, Benowitz NL. PMID: 18004205.
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Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):2065-71. Lin J, Swan GE, Shields PG, Benowitz NL, Gu J, Amos CI, de Andrade M, Spitz MR, Wu X. PMID: 17932354.
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Secondhand smoke exposure in Mexican discotheques. Nicotine Tob Res. 2007 Oct; 9(10):1021-6. Lazcano-Ponce E, Benowitz N, Sanchez-Zamorano LM, Barbosa-Sanchez L, Valdes-Salgado R, Jacob P, Diaz R, Hernandez-Avila M. PMID: 17852765.
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Cytisine for smoking cessation: a research agenda. Drug Alcohol Depend. 2008 Jan 01; 92(1-3):3-8. Etter JF, Lukas RJ, Benowitz NL, West R, Dresler CM. PMID: 17825502.
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Beliefs about health, smoking, and future smoking cessation among South Korean men hospitalized for cardiovascular disease. Heart Lung. 2007 Sep-Oct; 36(5):339-47. Sohn M, Stotts NA, Benowitz N, Christopherson D, Kim KS, Jang YS, Ahn MS, Froelicher ES. PMID: 17845880.
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CHRNA4 and tobacco dependence: from gene regulation to treatment outcome. Arch Gen Psychiatry. 2007 Sep; 64(9):1078-86. Hutchison KE, Allen DL, Filbey FM, Jepson C, Lerman C, Benowitz NL, Stitzel J, Bryan A, McGeary J, Haughey HM. PMID: 17768273.
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Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia. Nicotine Tob Res. 2007 Aug; 9(8):873-81. Williams JM, Gandhi KK, Steinberg ML, Foulds J, Ziedonis DM, Benowitz NL. PMID: 17654300.
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Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine. Cancer Epidemiol Biomarkers Prev. 2007 Jul; 16(7):1382-6. Stepanov I, Hecht SS, Lindgren B, Jacob P, Wilson M, Benowitz NL. PMID: 17627002.
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Cigarette smoking and the personalization of irinotecan therapy. J Clin Oncol. 2007 Jul 01; 25(19):2646-7. Benowitz NL. PMID: 17563392.
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Genetic and environmental sources of variation in heart rate response to infused nicotine in twins. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1057-64. Swan GE, Lessov-Schlaggar CN, Krasnow RE, Wilhelmsen KC, Jacob P, Benowitz NL. PMID: 17548663.
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CYP2B6 genotype does not alter nicotine metabolism, plasma levels, or abstinence with nicotine replacement therapy. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1312-4. Lee AM, Jepson C, Shields PG, Benowitz N, Lerman C, Tyndale RF. PMID: 17548706.
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Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism. Clin Pharmacol Ther. 2008 Jan; 83(1):115-21. Mwenifumbo JC, Lessov-Schlaggar CN, Zhou Q, Krasnow RE, Swan GE, Benowitz NL, Tyndale RF. PMID: 17522595; PMCID: PMC2921956.
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Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing. Pharmacogenomics. 2007 May; 8(5):519. Altman RB, Benowitz N, Gurwitz D, Lunshof J, Relling M, Lamba J, Wieben E, Mooney S, Giacomini K, Weiss S, Johnson JA, McLeod H, Flockhart D, Weinshilboum R, Shuldiner AR, Roden D, Krauss RM, Ratain M. PMID: 17465717.
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Modeling the relationship of cotinine and self-reported measures of maternal smoking during pregnancy: a deterministic approach. Nicotine Tob Res. 2007 Apr; 9(4):453-65. Dukic VM, Niessner M, Benowitz N, Hans S, Wakschlag L. PMID: 17454700.
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The pharmacogenetics research network: from SNP discovery to clinical drug response. Clin Pharmacol Ther. 2007 Mar; 81(3):328-45. Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I, Pharmacogenetics Research Network. PMID: 17339863; PMCID: PMC5006950.
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Urine nicotine metabolites and smoking behavior in a multiracial/multiethnic national sample of young adults. Am J Epidemiol. 2007 Apr 15; 165(8):901-10. Kandel DB, Hu MC, Schaffran C, Udry JR, Benowitz NL. PMID: 17322544.
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Determination of phenolic metabolites of polycyclic aromatic hydrocarbons in human urine as their pentafluorobenzyl ether derivatives using liquid chromatography-tandem mass spectrometry. Anal Chem. 2007 Jan 15; 79(2):587-98. Jacob P, Wilson M, Benowitz NL. PMID: 17222024.
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Population pharmacokinetics of nicotine and its metabolites I. Model development. J Pharmacokinet Pharmacodyn. 2007 Feb; 34(1):5-21. Levi M, Dempsey DA, Benowitz NL, Sheiner LB. PMID: 17206524.
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Prediction methods for nicotine clearance using cotinine and 3-hydroxy-cotinine spot saliva samples II. Model application. J Pharmacokinet Pharmacodyn. 2007 Feb; 34(1):23-34. Levi M, Dempsey DA, Benowitz NL, Sheiner LB. PMID: 17206525.
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Nicotine, cotinine, withdrawal, and craving patterns during smoking and nicotine nasal spray use: results from a pilot study with African American men. Nicotine Tob Res. 2007 Jan; 9(1):65-82. Mabry PL, Tooze JA, Moser RP, Augustson EM, Malcolm RJ, Benowitz NL. PMID: 17365738.
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The variability of urinary cotinine levels in young children: implications for measuring ETS exposure. Nicotine Tob Res. 2007 Jan; 9(1):83-92. Matt GE, Hovell MF, Quintana PJ, Zakarian J, Liles S, Meltzer SB, Benowitz NL. PMID: 17365739.
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Cotinine levels in relation to smoking behavior and addiction in young adolescent smokers. Nicotine Tob Res. 2007 Jan; 9(1):129-35. Rubinstein ML, Thompson PJ, Benowitz NL, Shiffman S, Moscicki AB. PMID: 17365743.
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Nicotine intake and dose response when smoking reduced-nicotine content cigarettes. Clin Pharmacol Ther. 2006 Dec; 80(6):703-14. Benowitz NL, Jacob P, Herrera B. PMID: 17178270.
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Pharmacogenomics: challenges and opportunities. Ann Intern Med. 2006 Nov 21; 145(10):749-57. Roden DM, Altman RB, Benowitz NL, Flockhart DA, Giacomini KM, Johnson JA, Krauss RM, McLeod HL, Ratain MJ, Relling MV, Ring HZ, Shuldiner AR, Weinshilboum RM, Weiss ST, Pharmacogenetics Research Network. PMID: 17116919; PMCID: PMC5006954.
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CYP2A6 genotype and the metabolism and disposition kinetics of nicotine. Clin Pharmacol Ther. 2006 Nov; 80(5):457-67. Benowitz NL, Swan GE, Jacob P, Lessov-Schlaggar CN, Tyndale RF. PMID: 17112802.
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Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance. Clin Pharmacol Ther. 2006 Nov; 80(5):522-30. Hukkanen J, Jacob P, Benowitz NL. PMID: 17112808.
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Evaluation of urinary trans-3'-hydroxycotinine as a biomarker of children's environmental tobacco smoke exposure. Biomarkers. 2006 Nov-Dec; 11(6):507-23. Matt GE, Quintana PJ, Liles S, Hovell MF, Zakarian JM, Jacob P, Benowitz NL. PMID: 17056471.
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Cotinine concentration in smokers from different countries: relationship with amount smoked and cigarette type. Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1799-804. Blackford AL, Yang G, Hernandez-Avila M, Przewozniak K, Zatonski W, Figueiredo V, Avila-Tang E, Ma J, Benowitz NL, Samet JM. PMID: 17021350.
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Gamma-hydroxybutyrate and ethanol effects and interactions in humans. J Clin Psychopharmacol. 2006 Oct; 26(5):524-9. Thai D, Dyer JE, Benowitz NL, Haller CA. PMID: 16974199; PMCID: PMC2766839.
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Exposure to second-hand smoke air pollution assessed from bar patrons' urinary cotinine. Nicotine Tob Res. 2006 Oct; 8(5):701-11. Repace J, Hughes E, Benowitz N. PMID: 17008197.
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Determinants of the rate of nicotine metabolism and effects on smoking behavior. Clin Pharmacol Ther. 2006 Oct; 80(4):319-30. Johnstone E, Benowitz N, Cargill A, Jacob R, Hinks L, Day I, Murphy M, Walton R. PMID: 17015050.
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Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Arch Intern Med. 2006 Sep 25; 166(17):1915-22. Pletcher MJ, Hulley BJ, Houston T, Kiefe CI, Benowitz N, Sidney S. PMID: 17000950.
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Anabasine toxicity from a topical folk remedy. Clin Pediatr (Phila). 2006 Sep; 45(7):669-71. Murphy NG, Albin C, Tai W, Benowitz NL. PMID: 16928847.
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Guidelines on nicotine dose selection for in vivo research. Psychopharmacology (Berl). 2007 Feb; 190(3):269-319. Matta SG, Balfour DJ, Benowitz NL, Boyd RT, Buccafusco JJ, Caggiula AR, Craig CR, Collins AC, Damaj MI, Donny EC, Gardiner PS, Grady SR, Heberlein U, Leonard SS, Levin ED, Lukas RJ, Markou A, Marks MJ, McCallum SE, Parameswaran N, Perkins KA, Picciotto MR, Quik M, Rose JE, Rothenfluh A, Schafer WR, Stolerman IP, Tyndale RF, Wehner JM, Zirger JM. PMID: 16896961.
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Salivary cotinine concentration versus self-reported cigarette smoking: Three patterns of inconsistency in adolescence. Nicotine Tob Res. 2006 Aug; 8(4):525-37. Kandel DB, Schaffran C, Griesler PC, Hu MC, Davies M, Benowitz N. PMID: 16920650; PMCID: PMC2538943.
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Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine Tob Res. 2006 Aug; 8(4):600-22. Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. PMID: 16920658; PMCID: PMC6615727.
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Within-subject variation of the salivary 3HC/COT ratio in regular daily smokers: prospects for estimating CYP2A6 enzyme activity in large-scale surveys of nicotine metabolic rate. J Anal Toxicol. 2006 Jul-Aug; 30(6):386-9. Lea RA, Dickson S, Benowitz NL. PMID: 16872570.
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Intraindividual variability of plasma antioxidants, markers of oxidative stress, C-reactive protein, cotinine, and other biomarkers. Epidemiology. 2006 Jul; 17(4):404-12. Block G, Dietrich M, Norkus E, Jensen C, Benowitz NL, Morrow JD, Hudes M, Packer L. PMID: 16755268.
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Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res. 2006 Jun 15; 66(12):5993-6. Wu X, Spitz MR, Amos CI, Lin J, Shao L, Gu J, de Andrade M, Benowitz NL, Shields PG, Swan GE. PMID: 16778168.
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Directly measured secondhand smoke exposure and COPD health outcomes. BMC Pulm Med. 2006 Jun 06; 6:12. Eisner MD, Balmes J, Yelin EH, Katz PP, Hammond SK, Benowitz N, Blanc PD. PMID: 16756671; PMCID: PMC1524811.
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A genome-wide screen for nicotine dependence susceptibility loci. Am J Med Genet B Neuropsychiatr Genet. 2006 Jun 05; 141B(4):354-60. Swan GE, Hops H, Wilhelmsen KC, Lessov-Schlaggar CN, Cheng LS, Hudmon KS, Amos CI, Feiler HS, Ring HZ, Andrews JA, Tildesley E, Benowitz N. PMID: 16671072; PMCID: PMC2563426.
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Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation. Clin Pharmacol Ther. 2006 Jun; 79(6):600-8. Lerman C, Tyndale R, Patterson F, Wileyto EP, Shields PG, Pinto A, Benowitz N. PMID: 16765148.
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Female sex and oral contraceptive use accelerate nicotine metabolism. Clin Pharmacol Ther. 2006 May; 79(5):480-8. Benowitz NL, Lessov-Schlaggar CN, Swan GE, Jacob P. PMID: 16678549.
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Smoking habits, nicotine use, and congenital malformations. Obstet Gynecol. 2006 May; 107(5):1166; author reply 1168. Le Houezec J, Benowitz NL. PMID: 16648425.
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Characterization of the novel CYP2A6*21 allele using in vivo nicotine kinetics. Eur J Clin Pharmacol. 2006 Jun; 62(6):481-4. Al Koudsi N, Mwenifumbo JC, Sellers EM, Benowitz NL, Swan GE, Tyndale RF. PMID: 16758265.
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Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction. Am J Epidemiol. 2006 Jun 01; 163(11):1035-41. Grosso LM, Triche EW, Belanger K, Benowitz NL, Holford TR, Bracken MB. PMID: 16641310.
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Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine Tob Res. 2006 Apr; 8(2):169-91. Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. PMID: 16766411.
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Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy. Mol Psychiatry. 2006 Apr; 11(4):400-9. Malaiyandi V, Lerman C, Benowitz NL, Jepson C, Patterson F, Tyndale RF. PMID: 16402128.
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Ethnic differences in nicotine metabolic rate among New Zealanders. N Z Med J. 2005 Dec 16; 118(1227):U1773. Lea R, Benowitz N, Green M, Fowles J, Vishvanath A, Dickson S, Lea M, Woodward A, Chambers G, Phillips D. PMID: 16372023.
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Support for previously identified alcoholism susceptibility Loci in a cohort selected for smoking behavior. Alcohol Clin Exp Res. 2005 Dec; 29(12):2108-15. Wilhelmsen KC, Swan GE, Cheng LS, Lessov-Schlaggar CN, Amos CI, Feiler HS, Hudmon KS, Ring HZ, Andrews JA, Tildesley E, Benowitz NL, Hops H. PMID: 16385180.
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Hemodynamic effects of ephedra-free weight-loss supplements in humans. Am J Med. 2005 Sep; 118(9):998-1003. Haller CA, Benowitz NL, Jacob P. PMID: 16164886.
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Effect of pregnancy on a measure of FMO3 activity. Br J Clin Pharmacol. 2005 Aug; 60(2):224-6. Hukkanen J, Dempsey D, Jacob P, Benowitz NL. PMID: 16042678; PMCID: PMC1884929.
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Increased nicotine and cotinine levels in smokers with schizophrenia and schizoaffective disorder is not a metabolic effect. Schizophr Res. 2005 Nov 15; 79(2-3):323-35. Williams JM, Ziedonis DM, Abanyie F, Steinberg ML, Foulds J, Benowitz NL. PMID: 15961287.
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Short-term metabolic and hemodynamic effects of ephedra and guarana combinations. Clin Pharmacol Ther. 2005 Jun; 77(6):560-71. Haller CA, Jacob P, Benowitz NL. PMID: 15961987.
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Toward a comprehensive long term nicotine policy. Tob Control. 2005 Jun; 14(3):161-5. Gray N, Henningfield JE, Benowitz NL, Connolly GN, Dresler C, Fagerstrom K, Jarvis MJ, Boyle P. PMID: 15923465; PMCID: PMC1748036.
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Carcinogen exposure during short-term switching from regular to "light" cigarettes. Cancer Epidemiol Biomarkers Prev. 2005 Jun; 14(6):1376-83. Benowitz NL, Jacob P, Bernert JT, Wilson M, Wang L, Allen F, Dempsey D. PMID: 15941944.
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Metabolism and disposition kinetics of nicotine. Pharmacol Rev. 2005 Mar; 57(1):79-115. Hukkanen J, Jacob P, Benowitz NL. PMID: 15734728.
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Influence of menstrual cycle on cytochrome P450 2A6 activity and cardiovascular effects of nicotine. Clin Pharmacol Ther. 2005 Mar; 77(3):159-69. Hukkanen J, Gourlay SG, Kenkare S, Benowitz NL. PMID: 15735610.
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Mechanistic pharmacokinetic modelling of ephedrine, norephedrine and caffeine in healthy subjects. Br J Clin Pharmacol. 2005 Mar; 59(3):335-45. Csajka C, Haller CA, Benowitz NL, Verotta D. PMID: 15752380; PMCID: PMC1884794.
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Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence. Pharmacogenet Genomics. 2005 Feb; 15(2):115-25. Swan GE, Benowitz NL, Lessov CN, Jacob P, Tyndale RF, Wilhelmsen K. PMID: 15861035.
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Caffeine-herbal ephedra combination increases resting energy expenditure, heart rate and blood pressure. Clin Exp Pharmacol Physiol. 2005 Jan-Feb; 32(1-2):47-53. Vukovich MD, Schoorman R, Heilman C, Jacob P, Benowitz NL. PMID: 15730434.
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Effect of menthol on the pharmacokinetics and pharmacodynamics of felodipine in healthy subjects. Eur J Clin Pharmacol. 2005 Jan; 60(11):785-90. Gelal A, Balkan D, Ozzeybek D, Kaplan YC, Gurler S, Guven H, Benowitz NL. PMID: 15592925.
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Determinants of salivary cotinine levels among current smokers in Mexico. Nicotine Tob Res. 2004 Dec; 6(6):997-1008. Campuzano JC, Hernandez-Avila M, Jaakkola MS, Lazcano Ponce E, Kuri Morales P, Bautista P, Benowitz NL, Ceraso M, Blackford A, Samet JM. PMID: 15801572.
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Cigarette smoking and infection. Arch Intern Med. 2004 Nov 08; 164(20):2206-16. Arcavi L, Benowitz NL. PMID: 15534156.
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Clarification of SRNT workgroup guidelines for measures in clinical trials of smoking cessation therapies. Nicotine Tob Res. 2004 Oct; 6(5):863-4. Hughes JR, Benowitz N, Hatsukami D, Mermelstein RJ, Shiffman S. PMID: 15700922.
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Pharmacogenetics of nicotine metabolism in twins: methods and procedures. Twin Res. 2004 Oct; 7(5):435-48. Swan GE, Benowitz NL, Jacob P, Lessov CN, Tyndale RF, Wilhelmsen K, Krasnow RE, McElroy MR, Moore SE, Wambach M. PMID: 15527659.
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Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity. Clin Pharmacol Ther. 2004 Jul; 76(1):64-72. Dempsey D, Tutka P, Jacob P, Allen F, Schoedel K, Tyndale RF, Benowitz NL. PMID: 15229465.
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Reducing tobacco addiction through tobacco product regulation. Tob Control. 2004 Jun; 13(2):132-5. Henningfield JE, Benowitz NL, Connolly GN, Davis RM, Gray N, Myers ML, Zeller M. PMID: 15175528; PMCID: PMC1747873.
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Mentholated cigarette smoking inhibits nicotine metabolism. J Pharmacol Exp Ther. 2004 Sep; 310(3):1208-15. Benowitz NL, Herrera B, Jacob P. PMID: 15084646.
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Enhanced stimulant and metabolic effects of combined ephedrine and caffeine. Clin Pharmacol Ther. 2004 Apr; 75(4):259-73. Haller CA, Jacob P, Benowitz NL. PMID: 15060505.
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Concentrations of ephedra alkaloids and caffeine in commercial dietary supplements. J Anal Toxicol. 2004 Apr; 28(3):145-51. Haller CA, Duan M, Benowitz NL, Jacob P. PMID: 15107143.
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Determination of ephedra alkaloid and caffeine concentrations in dietary supplements and biological fluids. J Anal Toxicol. 2004 Apr; 28(3):152-9. Jacob P, Haller CA, Duan M, Yu L, Peng M, Benowitz NL. PMID: 15107144.
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Pharmacotherapy for smoking cessation during pregnancy. Nicotine Tob Res. 2004 Apr; 6 Suppl 2:S189-202. Benowitz N, Dempsey D. PMID: 15203821.
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Individualizing nicotine replacement therapy for the treatment of tobacco dependence: a randomized trial. Ann Intern Med. 2004 Mar 16; 140(6):426-33. Lerman C, Kaufmann V, Rukstalis M, Patterson F, Perkins K, Audrain-McGovern J, Benowitz N. PMID: 15023708.
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Bupropion in breast milk: an exposure assessment for potential treatment to prevent post-partum tobacco use. Tob Control. 2004 Mar; 13(1):52-6. Haas JS, Kaplan CP, Barenboim D, Jacob P, Benowitz NL. PMID: 14985597; PMCID: PMC1747823.
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High rates of sustained smoking cessation in women hospitalized with cardiovascular disease: the Women's Initiative for Nonsmoking (WINS). Circulation. 2004 Feb 10; 109(5):587-93. Sivarajan Froelicher ES, Miller NH, Christopherson DJ, Martin K, Parker KM, Amonetti M, Lin Z, Sohn M, Benowitz N, Taylor CB, Bacchetti P. PMID: 14769679.
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Smoking less as a treatment goal for those who cannot stop smoking. Am J Med. 2004 Feb 01; 116(3):203-5. Benowitz NL. PMID: 14749168.
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The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial. Pharmacogenomics J. 2004; 4(3):184-92. Lerman C, Wileyto EP, Patterson F, Rukstalis M, Audrain-McGovern J, Restine S, Shields PG, Kaufmann V, Redden D, Benowitz N, Berrettini WH. PMID: 15007373.
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Central terminals of nociceptors are targets for nicotine suppression of inflammation. Neuroscience. 2004; 123(3):777-84. Miao FJ, Green PG, Benowitz N, Levine JD. PMID: 14706790.
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Clonidine for smoking cessation. Cochrane Database Syst Rev. 2004; (3):CD000058. Gourlay SG, Stead LF, Benowitz NL. PMID: 15266422; PMCID: PMC7038651.
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Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism. Clin Pharmacol Ther. 2003 Nov; 74(5):468-74. Benowitz NL, Peng M, Jacob P. PMID: 14586387.
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Tobacco use and dependence. Semin Oncol Nurs. 2003 Nov; 19(4):250-60. Sohn M, Hartley C, Froelicher ES, Benowitz NL. PMID: 14702859.
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Nicotine metabolite ratio as a predictor of cigarette consumption. Nicotine Tob Res. 2003 Oct; 5(5):621-4. Benowitz NL, Pomerleau OF, Pomerleau CS, Jacob P. PMID: 14577978.
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Environmental and genetic determinants of tobacco use: methodology for a multidisciplinary, longitudinal family-based investigation. Cancer Epidemiol Biomarkers Prev. 2003 Oct; 12(10):994-1005. Swan GE, Hudmon KS, Jack LM, Hemberger K, Carmelli D, Khroyan TV, Ring HZ, Hops H, Andrews JA, Tildesley E, McBride D, Benowitz N, Webster C, Wilhelmsen KC, Feiler HS, Koenig B, Caron L, Illes J, Cheng LS. PMID: 14578134; PMCID: PMC2587265.
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Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial. Ann Intern Med. 2003 Aug 19; 139(4):258-66. Abrams DI, Hilton JF, Leiser RJ, Shade SB, Elbeik TA, Aweeka FT, Benowitz NL, Bredt BM, Kosel B, Aberg JA, Deeks SG, Mitchell TF, Mulligan K, Bacchetti P, McCune JM, Schambelan M. PMID: 12965981.
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Influence of menthol on caffeine disposition and pharmacodynamics in healthy female volunteers. Eur J Clin Pharmacol. 2003 Sep; 59(5-6):417-22. Gelal A, Guven H, Balkan D, Artok L, Benowitz NL. PMID: 12915954.
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Cigarette smoking and cardiovascular disease: pathophysiology and implications for treatment. Prog Cardiovasc Dis. 2003 Jul-Aug; 46(1):91-111. Benowitz NL. PMID: 12920702.
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Individual differences in nicotine intake per cigarette. Cancer Epidemiol Biomarkers Prev. 2003 May; 12(5):468-71. Patterson F, Benowitz N, Shields P, Kaufmann V, Jepson C, Wileyto P, Kucharski S, Lerman C. PMID: 12750245.
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Determinants of salivary cotinine concentrations in Chinese male smokers. Prev Med. 2003 Mar; 36(3):282-90. Jaakkola MS, Ma J, Yang G, Chin MF, Benowitz NL, Ceraso M, Samet JM. PMID: 12634019.
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Once-daily dosing of aminoglycosides: how much monitoring is truly required? Am J Med. 2003 Feb 15; 114(3):239-40. Winston L, Benowitz N. PMID: 12637142.
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Basic cardiovascular research and its implications for the medicinal use of nicotine. J Am Coll Cardiol. 2003 Feb 05; 41(3):497-8. Benowitz NL. PMID: 12575982.
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Does menthol enhance the addictiveness of cigarettes? An agenda for research. Nicotine Tob Res. 2003 Feb; 5(1):9-11. Henningfield JE, Benowitz NL, Ahijevych K, Garrett BE, Connolly GN, Wayne GF. PMID: 12745502.
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Vitamin C supplementation decreases oxidative stress biomarker f2-isoprostanes in plasma of nonsmokers exposed to environmental tobacco smoke. Nutr Cancer. 2003; 45(2):176-84. Dietrich M, Block G, Benowitz NL, Morrow JD, Hudes M, Jacob P, Norkus EP, Packer L. PMID: 12881011.
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Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy. Cancer Epidemiol Biomarkers Prev. 2002 Dec; 11(12):1668-73. Jacob P, Hatsukami D, Severson H, Hall S, Yu L, Benowitz NL. PMID: 12496059.
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Women's Initiative for Nonsmoking (WINS V): under-use of nicotine replacement therapy. Heart Lung. 2002 Sep-Oct; 31(5):368-73. Mahrer-Imhof R, Froelicher ES, Li WW, Parker KM, Benowitz N. PMID: 12487015.
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Modeling nicotine arterial-venous differences to predict arterial concentrations and input based on venous measurements: application to smokeless tobacco and nicotine gum. J Pharmacokinet Pharmacodyn. 2002 Aug; 29(4):383-402. Pitsiu M, Gries JM, Benowitz N, Gourlay SG, Verotta D. PMID: 12518710.
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Smoking cessation trials targeted to racial and economic minority groups. JAMA. 2002 Jul 24-31; 288(4):497-9. Benowitz NL. PMID: 12132983.
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Maternal smoking during pregnancy and severe antisocial behavior in offspring: a review. Am J Public Health. 2002 Jun; 92(6):966-74. Wakschlag LS, Pickett KE, Cook E, Benowitz NL, Leventhal BL. PMID: 12036791; PMCID: PMC1447496.
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Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use. Clin Pharmacol Ther. 2002 Jun; 71(6):421-32. Haller CA, Jacob P, Benowitz NL. PMID: 12087345.
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Cardiovascular effects of nasal and transdermal nicotine and cigarette smoking. Hypertension. 2002 Jun; 39(6):1107-12. Benowitz NL, Hansson A, Jacob P. PMID: 12052850.
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Accelerated metabolism of nicotine and cotinine in pregnant smokers. J Pharmacol Exp Ther. 2002 May; 301(2):594-8. Dempsey D, Jacob P, Benowitz NL. PMID: 11961061.
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Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster. J Pharm Sci. 2002 May; 91(5):1343-50. Campbell BJ, Rowbotham M, Davies PS, Jacob P, Benowitz NL. PMID: 11977110.
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Influence of arterial vs. venous sampling site on nicotine tolerance model selection and parameter estimation. J Pharmacokinet Pharmacodyn. 2002 Feb; 29(1):49-66. Schaedeli F, Pitsiu M, Benowitz NL, Gourlay SG, Verotta D. PMID: 12194535.
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Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans. J Natl Cancer Inst. 2002 Jan 16; 94(2):108-15. Benowitz NL, Pérez-Stable EJ, Herrera B, Jacob P. PMID: 11792749.
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Reducing tobacco harm: research challenges and issues. Nicotine Tob Res. 2002; 4 Suppl 2:S89-101. Hatsukami DK, Slade J, Benowitz NL, Giovino GA, Gritz ER, Leischow S, Warner KE. PMID: 12573171.
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Deficient C-oxidation of nicotine continued. Clin Pharmacol Ther. 2001 Dec; 70(6):567. Benowitz NL, Griffin C, Tyndale R. PMID: 11753274.
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Cardiovascular effects of carbon monoxide and cigarette smoking. J Am Coll Cardiol. 2001 Nov 15; 38(6):1633-8. Zevin S, Saunders S, Gourlay SG, Jacob P, Benowitz NL. PMID: 11704374.
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Prenatal nicotine exposure alters pulmonary function in newborn rhesus monkeys. Am J Respir Crit Care Med. 2001 Sep 15; 164(6):989-94. Sekhon HS, Keller JA, Benowitz NL, Spindel ER. PMID: 11587984.
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Predictors of cotinine levels in US children: data from the Third National Health and Nutrition Examination Survey. Chest. 2001 Sep; 120(3):718-24. Mannino DM, Caraballo R, Benowitz N, Repace J. PMID: 11555498.
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Safety of nicotine in smokers with hypertension. Am J Hypertens. 2001 Jul; 14(7 Pt 1):731-2. Benowitz NL. PMID: 11465662.
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Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine. Br J Pharmacol. 2001 May; 133(1):23-8. Miao FJ, Benowitz NL, Levine JD. PMID: 11325790; PMCID: PMC1572752.
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Systemic nicotine exposure in tobacco harvesters. Arch Environ Health. 2001 May-Jun; 56(3):257-63. D'Alessandro A, Benowitz NL, Muzi G, Eisner MD, Filiberto S, Fantozzi P, Montanari L, Abbritti G. PMID: 11480503.
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Risks and benefits of nicotine to aid smoking cessation in pregnancy. Drug Saf. 2001; 24(4):277-322. Dempsey DA, Benowitz NL. PMID: 11330657.
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Trans-3'-hydroxycotinine: disposition kinetics, effects and plasma levels during cigarette smoking. Br J Clin Pharmacol. 2001 Jan; 51(1):53-9. Benowitz NL, Jacob P. PMID: 11167665; PMCID: PMC2014428.
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Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med. 2000 Dec 21; 343(25):1833-8. Haller CA, Benowitz NL. PMID: 11117974.
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Simultaneous determination of mecamylamine, nicotine, and cotinine in plasma by gas chromatography-mass spectrometry. J Pharm Biomed Anal. 2000 Sep; 23(4):653-61. Jacob P, Wu S, Yu L, Benowitz NL. PMID: 10975241.
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Nicotine blood levels and subjective craving for cigarettes. Pharmacol Biochem Behav. 2000 Jul; 66(3):553-8. Jarvik ME, Madsen DC, Olmstead RE, Iwamoto-Schaap PN, Elins JL, Benowitz NL. PMID: 10899369.
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Nicotine-mecamylamine interactions. Clin Pharmacol Ther. 2000 Jul; 68(1):58-66. Zevin S, Jacob P, Benowitz NL. PMID: 10945316.
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Nasal mucosal versus gastrointestinal absorption of nasally administered cocaine. Eur J Clin Pharmacol. 2000 Jul; 56(4):305-10. Fattinger K, Benowitz NL, Jones RT, Verotta D. PMID: 10954344.
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Clinical pharmacology of oral cotinine. Drug Alcohol Depend. 2000 Jul 01; 60(1):13-8. Zevin S, Jacob P, Geppetti P, Benowitz NL. PMID: 10821985.
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Effects of cigarette smoking and carbon monoxide on nicotine and cotinine metabolism. Clin Pharmacol Ther. 2000 Jun; 67(6):653-9. Benowitz NL, Jacob P. PMID: 10872647.
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Safety of intra-amniotic digoxin administration before late second-trimester abortion by dilation and evacuation. Am J Obstet Gynecol. 2000 May; 182(5):1063-6. Drey EA, Thomas LJ, Benowitz NL, Goldschlager N, Darney PD. PMID: 10819828.
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Nicotine metabolism and elimination kinetics in newborns. Clin Pharmacol Ther. 2000 May; 67(5):458-65. Dempsey D, Jacob P, Benowitz NL. PMID: 10824624.
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Nicotine impairs endothelium-dependent dilatation in human veins in vivo. Clin Pharmacol Ther. 2000 Apr; 67(4):391-7. Chalon S, Moreno H, Benowitz NL, Hoffman BB, Blaschke TF. PMID: 10801248.
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Diagnosis and treatment of nicotine dependence with emphasis on nicotine replacement therapy. A status report. Eur Heart J. 2000 Mar; 21(6):438-45. Balfour D, Benowitz N, Fagerström K, Kunze M, Keil U. PMID: 10681484.
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Clonidine for smoking cessation. Cochrane Database Syst Rev. 2000; (2):CD000058. Gourlay SG, Stead LF, Benowitz NL. PMID: 10796479.
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Influence of age on the thermic response to caffeine in women. Metabolism. 2000 Jan; 49(1):101-7. Arciero PJ, Bougopoulos CL, Nindl BC, Benowitz NL. PMID: 10647072.
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The use of pharmacotherapies for smoking cessation during pregnancy. Tob Control. 2000; 9 Suppl 3:III91-4. Benowitz NL, Dempsey DA, Goldenberg RL, Hughes JR, Dolan-Mullen P, Ogburn PL, Oncken C, Orleans CT, Slotkin TA, Whiteside HP, Yaffe S. PMID: 10982920; PMCID: PMC1766294.
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Ethnic differences in N-glucuronidation of nicotine and cotinine. J Pharmacol Exp Ther. 1999 Dec; 291(3):1196-203. Benowitz NL, Perez-Stable EJ, Fong I, Modin G, Herrera B, Jacob P. PMID: 10565842.
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Snuff, nicotine and cardiovascular disease: implications for tobacco control. J Am Coll Cardiol. 1999 Nov 15; 34(6):1791-3. Benowitz NL. PMID: 10577571.
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Coffee, alcohol, and the liver. Ann Epidemiol. 1999 Oct; 9(7):391-3. Sharp DS, Everhart JE, Benowitz NL. PMID: 10501405.
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Nicotine addiction. Prim Care. 1999 Sep; 26(3):611-31. Benowitz NL. PMID: 10436290.
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Disposition kinetics and effects of menthol. Clin Pharmacol Ther. 1999 Aug; 66(2):128-35. Gelal A, Jacob P, Yu L, Benowitz NL. PMID: 10460066.
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Drug interactions with tobacco smoking. An update. Clin Pharmacokinet. 1999 Jun; 36(6):425-38. Zevin S, Benowitz NL. PMID: 10427467.
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Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes. Am J Public Health. 1999 May; 89(5):731-6. Jacob P, Yu L, Shulgin AT, Benowitz NL. PMID: 10224986; PMCID: PMC1508721.
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Biomarkers of environmental tobacco smoke exposure. Environ Health Perspect. 1999 May; 107 Suppl 2:349-55. Benowitz NL. PMID: 10350520; PMCID: PMC1566286.
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Caffeine consumption and menstrual function. Am J Epidemiol. 1999 Mar 15; 149(6):550-7. Fenster L, Quale C, Waller K, Windham GC, Elkin EP, Benowitz N, Swan SH. PMID: 10084244.
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Occasional smoking in a study of premenopausal women. Am J Public Health. 1999 Mar; 89(3):420-1. Elkin EP, Windham GC, Benowitz NL, Swan SH. PMID: 10076502; PMCID: PMC1508611.
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The biology of nicotine dependence: from the 1988 Surgeon General's Report to the present and into the future. Nicotine Tob Res. 1999; 1 Suppl 2:S159-63. Benowitz NL. PMID: 11768175.
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Suppression of nicotine intake during ad libitum cigarette smoking by high-dose transdermal nicotine. J Pharmacol Exp Ther. 1998 Dec; 287(3):958-62. Benowitz NL, Zevin S, Jacob P. PMID: 9864279.
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Relationship of blood pressure, heart rate and behavioral mood state to norepinephrine kinetics in younger and older men following caffeine ingestion. Eur J Clin Nutr. 1998 Nov; 52(11):805-12. Arciero PJ, Gardner AW, Benowitz NL, Poehlman ET. PMID: 9846593.
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Gender differences in the pharmacology of nicotine addiction. Addict Biol. 1998 Oct; 3(4):383-404. Benowitz NL, Hatsukami D. PMID: 26735114.
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Clinical pharmacology of nicotine. Clin Dermatol. 1998 Sep-Oct; 16(5):557-64. Zevin S, Gourlay SG, Benowitz NL. PMID: 9787965.
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Caffeine withdrawal in normal school-age children. J Am Acad Child Adolesc Psychiatry. 1998 Aug; 37(8):858-65. Bernstein GA, Carroll ME, Dean NW, Crosby RD, Perwien AR, Benowitz NL. PMID: 9695448.
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Nicotine metabolism and intake in black and white smokers. JAMA. 1998 Jul 08; 280(2):152-6. Pérez-Stable EJ, Herrera B, Jacob P, Benowitz NL. PMID: 9669788.
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Dose-related cardiovascular and endocrine effects of transdermal nicotine. Clin Pharmacol Ther. 1998 Jul; 64(1):87-95. Zevin S, Jacob P, Benowitz NL. PMID: 9695723.
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Effects of stress on circulating nicotine and cotinine levels and in vitro nicotine metabolism in the rat. Psychopharmacology (Berl). 1998 Jun; 137(4):383-90. Winders SE, Grunberg NE, Benowitz NL, Alvares AP. PMID: 9676899.
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Importance of chronopharmacokinetics in design and evaluation of transdermal drug delivery systems. J Pharmacol Exp Ther. 1998 May; 285(2):457-63. Gries JM, Benowitz N, Verotta D. PMID: 9580583.
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Rate of caffeine metabolism and risk of spontaneous abortion. Am J Epidemiol. 1998 Mar 01; 147(5):503-10. Fenster L, Quale C, Hiatt RA, Wilson M, Windham GC, Benowitz NL. PMID: 9525538.
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Evaluation of pharmacokinetic methods used to estimate caffeine clearance and comparison with a Bayesian forecasting method. Ther Drug Monit. 1998 Feb; 20(1):78-87. Denaro CP, Jacob P, Benowitz NL. PMID: 9485560.
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Effects of cotinine on information processing in nonsmokers. Psychopharmacology (Berl). 1998 Jan; 135(2):127-32. Herzig KE, Callaway E, Halliday R, Naylor H, Benowitz NL. PMID: 9497017.
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Reducing the addictiveness of cigarettes. Council on Scientific Affairs, American Medical Association. Tob Control. 1998; 7(3):281-93. Henningfield JE, Benowitz NL, Slade J, Houston TP, Davis RM, Deitchman SD. PMID: 9825424; PMCID: PMC1763900.
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Birthing of clinical pharmacologists. Clin Pharmacol Ther. 1997 Dec; 62(6):587-91. Benowitz NL. PMID: 9433386.
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Nicotine content of the eclipse nicotine delivery device. Am J Public Health. 1997 Nov; 87(11):1865-6. Benowitz NL, Jacob P, Slade J, Yu L. PMID: 9366646; PMCID: PMC1381174.
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Treating tobacco addiction--nicotine or no nicotine? N Engl J Med. 1997 Oct 23; 337(17):1230-1. Benowitz NL. PMID: 9337385.
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Arteriovenous differences in plasma concentration of nicotine and catecholamines and related cardiovascular effects after smoking, nicotine nasal spray, and intravenous nicotine. Clin Pharmacol Ther. 1997 Oct; 62(4):453-63. Gourlay SG, Benowitz NL. PMID: 9357397.
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Caffeinated beverages, decaffeinated coffee, and spontaneous abortion. Epidemiology. 1997 Sep; 8(5):515-23. Fenster L, Hubbard AE, Swan SH, Windham GC, Waller K, Hiatt RA, Benowitz N. PMID: 9270953.
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Systemic absorption and effects of nicotine from smokeless tobacco. Adv Dent Res. 1997 Sep; 11(3):336-41. Benowitz NL. PMID: 9524434.
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The role of nicotine in smoking-related cardiovascular disease. Prev Med. 1997 Jul-Aug; 26(4):412-7. Benowitz NL. PMID: 9245658.
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Absorption kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol. 1997 Jul; 90(1):88-92. Zieman M, Fong SK, Benowitz NL, Banskter D, Darney PD. PMID: 9207820.
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Nicotine patch therapy in smoking cessation reduces the extent of exercise-induced myocardial ischemia. J Am Coll Cardiol. 1997 Jul; 30(1):125-30. Mahmarian JJ, Moyé LA, Nasser GA, Nagueh SF, Bloom MF, Benowitz NL, Verani MS, Byrd WG, Pratt CM. PMID: 9207632.
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Cardiovascular toxicity of nicotine: implications for nicotine replacement therapy. J Am Coll Cardiol. 1997 Jun; 29(7):1422-31. Benowitz NL, Gourlay SG. PMID: 9180099.
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Cotinine effects on nicotine metabolism. Clin Pharmacol Ther. 1997 Jun; 61(6):649-54. Zevin S, Jacob P, Benowitz N. PMID: 9209247.
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Pharmacodynamics of acute tolerance to multiple nicotinic effects in humans. J Pharmacol Exp Ther. 1997 Jun; 281(3):1238-46. Fattinger K, Verotta D, Benowitz NL. PMID: 9190859.
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Society for Research on Nicotine and Tobacco. Addiction. 1997 May; 92(5):615-33. Heishman SJ, Balfour DJ, Benowitz NL, Hatsukami DK, Lindstrom JM, Ockene JK. PMID: 9219386.
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Sources of variability in nicotine and cotinine levels with use of nicotine nasal spray, transdermal nicotine, and cigarette smoking. Br J Clin Pharmacol. 1997 Mar; 43(3):259-67. Benowitz NL, Zevin S, Jacob P. PMID: 9088580; PMCID: PMC2042749.
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Saliva cotinine levels as a function of collection method. Addiction. 1997 Mar; 92(3):347-51. Schneider NG, Jacob P, Nilsson F, Leischow SJ, Benowitz NL, Olmstead RE. PMID: 9219396.
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What should be the elements of any settlement with the tobacco industry? Tob Control. 1997; 6(1):1-4. Burns D, Benowitz N, N'Connolly GN, Cummings KM, Davis RM, Henningfield JE, Shopland DR, Warner KE. PMID: 9176975; PMCID: PMC1759535.
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Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat. Br J Pharmacol. 1997 Jan; 120(2):298-304. Miao FJ, Benowitz NL, Heller PH, Levine JD. PMID: 9117123; PMCID: PMC1564364.
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Individual differences in nicotine kinetics and metabolism in humans. NIDA Res Monogr. 1997; 173:48-64. Benowitz NL, Jacob P. PMID: 9260183.
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Determinants of plasma concentrations of nicotine and cotinine during cigarette smoking and transdermal nicotine treatment. Eur J Clin Pharmacol. 1997; 51(5):407-14. Gourlay SG, Benowitz NL, Forbes A, McNeil JJ. PMID: 9049583.
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Chronopharmacokinetics of nicotine. Clin Pharmacol Ther. 1996 Oct; 60(4):385-95. Gries JM, Benowitz N, Verotta D. PMID: 8873686.
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Orthostatic hypertension due to vascular adrenergic hypersensitivity. Hypertension. 1996 Jul; 28(1):42-6. Benowitz NL, Zevin S, Carlsen S, Wright J, Schambelan M, Cheitlin M. PMID: 8675262.
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The benefits of stopping smoking and the role of nicotine replacement therapy in older patients. Drugs Aging. 1996 Jul; 9(1):8-23. Gourlay SG, Benowitz NL. PMID: 8818582.
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Neural and endocrine circuits mediating inhibition of bradykinin-induced plasma extravasation by subcutaneous and spinal-intrathecal nicotine. J Pharmacol Exp Ther. 1996 Jun; 277(3):1510-6. Miao FJ, Benowitz N, Levine JD. PMID: 8667217.
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CYP2D6 phenotype and the metabolism of nicotine and cotinine. Pharmacogenetics. 1996 Jun; 6(3):239-42. Benowitz NL, Jacob P, Perez-Stable E. PMID: 8807663.
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The effect of liver disease on urine caffeine metabolite ratios. Clin Pharmacol Ther. 1996 Jun; 59(6):624-35. Denaro CP, Wilson M, Jacob P, Benowitz NL. PMID: 8681487.
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Individualizing medical treatment for tobacco dependence. Eur Respir J. 1996 Apr; 9(4):629-31. Sachs DP, Benowitz NL. PMID: 8726921.
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Validation of urine caffeine metabolite ratios with use of stable isotope-labeled caffeine clearance. Clin Pharmacol Ther. 1996 Mar; 59(3):284-96. Denaro CP, Wilson M, Jacob P, Benowitz NL. PMID: 8653991.
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Recurrent non-Q-wave myocardial infarction associated with toluene abuse. Am Heart J. 1996 Mar; 131(3):615-6. Hussain TF, Heidenreich PA, Benowitz N. PMID: 8604650.
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Predictors of carbon monoxide and hydrogen cyanide exposure in smoke inhalation patients. J Toxicol Clin Toxicol. 1996; 34(1):61-71. Shusterman D, Alexeeff G, Hargis C, Kaplan J, Sato R, Gelb A, Becker C, Benowitz N, Gillen M, Thollaug S, Balmes J. PMID: 8632515.
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Marijuana and hyperthermia. J Toxicol Clin Toxicol. 1996; 34(2):217-21. Walter FG, Bey TA, Ruschke DS, Benowitz NL. PMID: 8618257.
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Absorption rate of methylxanthines following capsules, cola and chocolate. Eur J Clin Pharmacol. 1996; 51(3-4):319-25. Mumford GK, Benowitz NL, Evans SM, Kaminski BJ, Preston KL, Sannerud CA, Silverman K, Griffiths RR. PMID: 9010706.
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Pharmacology of nicotine: addiction and therapeutics. Annu Rev Pharmacol Toxicol. 1996; 36:597-613. Benowitz NL. PMID: 8725403.
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Society for Research on Nicotine and Tobacco. Addiction. 1996 Jan; 91(1):129-44. Perkins KA, Benowitz N, Henningfield J, Newhouse P, Pomerleau O, Swan G. PMID: 8822021.
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Cotinine as a biomarker of environmental tobacco smoke exposure. Epidemiol Rev. 1996; 18(2):188-204. Benowitz NL. PMID: 9021312.
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Smoking cessation and the nicotine patch: much more to be done. J Gen Intern Med. 1995 Dec; 10(12):697-8. Kimmel SE, Benowitz N. PMID: 8770725.
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Sympathomimetic effects of paraxanthine and caffeine in humans. Clin Pharmacol Ther. 1995 Dec; 58(6):684-91. Benowitz NL, Jacob P, Mayan H, Denaro C. PMID: 8529334.
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Is clonidine an effective smoking cessation therapy? Drugs. 1995 Aug; 50(2):197-207. Gourlay SG, Benowitz NL. PMID: 8521754.
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Cigarette smoking sensitizes and desensitizes impedance-measured ADP-induced platelet aggregation in whole blood. Thromb Haemost. 1995 Aug; 74(2):730-5. Sharp DS, Benowitz NL, Bath PM, Martin JF, Beswick AD, Elwood PC. PMID: 8585014.
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Effects of caffeine ingestion on NE kinetics, fat oxidation, and energy expenditure in younger and older men. Am J Physiol. 1995 Jun; 268(6 Pt 1):E1192-8. Arciero PJ, Gardner AW, Calles-Escandon J, Benowitz NL, Poehlman ET. PMID: 7611396.
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Nicotine patches. BMJ. 1995 May 27; 310(6991):1409-10. Benowitz NL. PMID: 7646675; PMCID: PMC2549779.
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Deficient C-oxidation of nicotine. Clin Pharmacol Ther. 1995 May; 57(5):590-4. Benowitz NL, Jacob P, Sachs DP. PMID: 7768082.
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Cigarettes and addiction. BMJ. 1995 Apr 29; 310(6987):1082-3. Henningfield JE, Benowitz NL. PMID: 7742663; PMCID: PMC2549491.
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Is serum cotinine a better measure of cigarette smoking than self-report? Prev Med. 1995 Mar; 24(2):171-9. Pérez-Stable EJ, Benowitz NL, Marín G. PMID: 7597020.
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Re: "Alcohol, smoking, coffee, and cirrhosis" and "coffee and serum gamma-glutamyltransferase: a study of self-defense officials in Japan". Am J Epidemiol. 1995 Mar 01; 141(5):480-2. Sharp DS, Benowitz NL. PMID: 7879794.
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Metabolic interactions between surplus dietary energy intake and cigarette smoking or its cessation. Am J Physiol. 1994 Dec; 267(6 Pt 1):E1023-34. Neese RA, Benowitz NL, Hoh R, Faix D, LaBua A, Pun K, Hellerstein MK. PMID: 7810617.
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Metabolism of nicotine to cotinine studied by a dual stable isotope method. Clin Pharmacol Ther. 1994 Nov; 56(5):483-93. Benowitz NL, Jacob P. PMID: 7955812.
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Caffeine and coffee: effects on health and cardiovascular disease. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1994 Oct; 109(2):173-89. Chou TM, Benowitz NL. PMID: 7881818.
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Re: "Inconsistent associations of caffeine-containing beverages with blood pressure and with lipoproteins: the CARDIA Study". Am J Epidemiol. 1994 Oct 01; 140(7):665-7. Sharp DS, Benowitz NL. PMID: 7980844.
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Role of vagal afferents and spinal pathways modulating inhibition of bradykinin-induced plasma extravasation by intrathecal nicotine. J Neurophysiol. 1994 Sep; 72(3):1199-207. Miao FJ, Jänig W, Dallman MF, Benowitz NL, Heller PH, Basbaum AI, Levine JD. PMID: 7807204.
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A proposal to develop meaningful labeling for cigarettes. JAMA. 1994 Jul 27; 272(4):312-4. Henningfield JE, Kozlowski LT, Benowitz NL. PMID: 8028146.
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Establishing a nicotine threshold for addiction. The implications for tobacco regulation. N Engl J Med. 1994 Jul 14; 331(2):123-5. Benowitz NL, Henningfield JE. PMID: 7818638.
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Divergent tolerance to metabolic and cardiovascular effects of nicotine in smokers with low and high levels of cigarette consumption. Clin Pharmacol Ther. 1994 Jul; 56(1):55-64. Arcavi L, Jacob P, Hellerstein M, Benowitz NL. PMID: 8033495.
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Environmental tobacco smoke hazards and benefits of work-site nonsmoking programs. West J Med. 1994 Jun; 160(6):562-3. Benowitz NL, Leistikow B. PMID: 8053178; PMCID: PMC1022561.
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Seizures associated with poisoning and drug overdose. Am J Emerg Med. 1994 May; 12(3):392-5. Olson KR, Kearney TE, Dyer JE, Benowitz NL, Blanc PD. PMID: 8179767.
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A low dose of subcutaneous nicotine improves information processing in non-smokers. Psychopharmacology (Berl). 1994 May; 114(4):628-34. Le Houezec J, Halliday R, Benowitz NL, Callaway E, Naylor H, Herzig K. PMID: 7855225.
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Caffeine effects on learning, performance, and anxiety in normal school-age children. J Am Acad Child Adolesc Psychiatry. 1994 Mar-Apr; 33(3):407-15. Bernstein GA, Carroll ME, Crosby RD, Perwien AR, Go FS, Benowitz NL. PMID: 8169187.
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Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine. J Pharmacol Exp Ther. 1994 Jan; 268(1):296-303. Benowitz NL, Jacob P, Fong I, Gupta S. PMID: 8301571.
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Effects of cigarette smoking and its cessation on lipid metabolism and energy expenditure in heavy smokers. J Clin Invest. 1994 Jan; 93(1):265-72. Hellerstein MK, Benowitz NL, Neese RA, Schwartz JM, Hoh R, Jacob P, Hsieh J, Faix D. PMID: 8282797; PMCID: PMC293761.
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Stereoselective metabolism of (S)-(-)-nicotine in humans: formation of trans-(S)-(-)-nicotine N-1'-oxide. Chem Res Toxicol. 1993 Nov-Dec; 6(6):880-8. Park SB, Jacob P, Benowitz NL, Cashman JR. PMID: 8117928.
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Seizures associated with poisoning and drug overdose. Am J Emerg Med. 1993 Nov; 11(6):565-8. Olson KR, Kearney TE, Dyer JE, Benowitz NL, Blanc PD. PMID: 8192750.
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Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. J Am Coll Cardiol. 1993 Oct; 22(4):1159-67. Benowitz NL, Fitzgerald GA, Wilson M, Zhang Q. PMID: 7691912.
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Saliva nicotine as an index of plasma levels in nicotine skin patch users. Ther Drug Monit. 1993 Oct; 15(5):431-5. Rose JE, Levin ED, Benowitz N. PMID: 8249050.
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Gas chromatographic-mass spectrometric method for determination of anabasine, anatabine and other tobacco alkaloids in urine of smokers and smokeless tobacco users. J Chromatogr. 1993 Sep 08; 619(1):49-61. Jacob P, Yu L, Liang G, Shulgin AT, Benowitz NL. PMID: 8245163.
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Smoking-induced coronary vasoconstriction: implications for therapeutic use of nicotine. J Am Coll Cardiol. 1993 Sep; 22(3):648-9. Benowitz NL. PMID: 8354793.
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Bioavailability and absorption kinetics of nicotine following application of a transdermal system. Br J Clin Pharmacol. 1993 Sep; 36(3):221-7. Gupta SK, Benowitz NL, Jacob P, Rolf CN, Gorsline J. PMID: 9114908; PMCID: PMC1364642.
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Higher levels of nicotine in arterial than in venous blood after cigarette smoking. Drug Alcohol Depend. 1993 Jun; 33(1):23-9. Henningfield JE, Stapleton JM, Benowitz NL, Grayson RF, London ED. PMID: 8370337.
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Clinical significance of genetic influences on cardiovascular drug metabolism. Cardiovasc Drugs Ther. 1993 Jun; 7(3):311-24. Arcavi L, Benowitz NL. PMID: 8103355.
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Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome. Clin Pharmacol Ther. 1993 May; 53(5):529-35. Lee BL, Wong D, Benowitz NL, Sullam PM. PMID: 8491064.
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Nicotine and cotinine elimination pharmacokinetics in smokers and nonsmokers. Clin Pharmacol Ther. 1993 Mar; 53(3):316-23. Benowitz NL, Jacob P. PMID: 8453850.
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The chronic infusion of nicotine into the developing chick embryo does not alter the density of (-)-[3H]nicotine-binding sites or vestibular function. Brain Res. 1993 Feb 26; 604(1-2):260-5. Roll RL, Jones TA, Benowitz NL, Morley BJ. PMID: 8457853.
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Adrenal medullary modulation of the inhibition of bradykinin-induced plasma extravasation by intrathecal nicotine. J Pharmacol Exp Ther. 1993 Feb; 264(2):839-44. Miao FJ, Dallman MF, Benowitz NL, Basbaum AI, Levine JD. PMID: 8094755.
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Nicotine replacement therapy. What has been accomplished--can we do better? Drugs. 1993 Feb; 45(2):157-70. Benowitz NL. PMID: 7681369.
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Clinical pharmacology and toxicology of cocaine. Pharmacol Toxicol. 1993 Jan; 72(1):3-12. Benowitz NL. PMID: 8441738.
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Pharmacokinetic-pharmacodynamic modeling of caffeine: tolerance to pressor effects. Clin Pharmacol Ther. 1993 Jan; 53(1):6-14. Shi J, Benowitz NL, Denaro CP, Sheiner LB. PMID: 8422743.
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A clinical pharmacological study of subcutaneous nicotine. Eur J Clin Pharmacol. 1993; 44(3):225-30. Le Houezec J, Jacob P, Benowitz NL. PMID: 8491235.
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Hydroxocobalamin as a cyanide antidote: safety, efficacy and pharmacokinetics in heavily smoking normal volunteers. J Toxicol Clin Toxicol. 1993; 31(2):277-94. Forsyth JC, Mueller PD, Becker CE, Osterloh J, Benowitz NL, Rumack BH, Hall AH. PMID: 8492341.
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Determination of the nicotine metabolite trans-3'-hydroxycotinine in urine of smokers using gas chromatography with nitrogen-selective detection or selected ion monitoring. J Chromatogr. 1992 Dec 02; 583(2):145-54. Jacob P, Shulgin AT, Yu L, Benowitz NL. PMID: 1478978.
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Chronically administered nicotine attenuates bradykinin-induced plasma extravasation and aggravates arthritis-induced joint injury in the rat. Neuroscience. 1992 Dec; 51(3):649-55. Miao FJ, Helms C, Benowitz NL, Basbaum AI, Heller PH, Levine JD. PMID: 1362599.
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Orthostatic hypotension in ciguatera fish poisoning. Arch Intern Med. 1992 Oct; 152(10):2131-3. Geller RJ, Benowitz NL. PMID: 1417387.
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The genetics of drug dependence: tobacco addiction. N Engl J Med. 1992 Sep 17; 327(12):881-3. Benowitz NL. PMID: 1508249.
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Workshop on problem-based learning as a method for teaching clinical pharmacology and therapeutics in medical school. J Clin Pharmacol. 1992 Sep; 32(9):779-97. Vestal RE, Benowitz NL. PMID: 1430298.
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Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide. Chem Res Toxicol. 1992 Sep-Oct; 5(5):639-46. Cashman JR, Park SB, Yang ZC, Wrighton SA, Jacob P, Benowitz NL. PMID: 1446003.
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Intravenous nicotine retards transdermal absorption of nicotine: evidence of blood flow--limited percutaneous absorption. Clin Pharmacol Ther. 1992 Sep; 52(3):223-30. Benowitz NL, Jacob P, Olsson P, Johansson CJ. PMID: 1526077.
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Sympathoadrenal contribution to nicotinic and muscarinic modulation of bradykinin-induced plasma extravasation in the knee joint of the rat. J Pharmacol Exp Ther. 1992 Sep; 262(3):889-95. Miao FJ, Benowitz NL, Basbaum AI, Levine JD. PMID: 1527731.
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Cardiotoxicity in the workplace. Occup Med. 1992 Jul-Sep; 7(3):465-78. Benowitz NL. PMID: 1496430.
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Cigarette smoking and nicotine addiction. Med Clin North Am. 1992 Mar; 76(2):415-37. Benowitz NL. PMID: 1548969.
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Smokeless tobacco, cardiovascular risk factors, and nicotine and cotinine levels in professional baseball players. Am J Public Health. 1992 Mar; 82(3):417-21. Siegel D, Benowitz N, Ernster VL, Grady DG, Hauck WW. PMID: 1536359; PMCID: PMC1694380.
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Nicotine elimination and tolerance in non-dependent cigarette smokers. Psychopharmacology (Berl). 1992; 109(4):449-56. Shiffman S, Zettler-Segal M, Kassel J, Paty J, Benowitz NL, O'Brien G. PMID: 1365861.
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How toxic is cocaine? Ciba Found Symp. 1992; 166:125-43; discussion 143-8. Benowitz NL. PMID: 1638909.
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National working conference on smoking and body weight. Task Force 2: Methods of assessment, strategies for research. Health Psychol. 1992; 11 Suppl:10-6. Henningfield JE, Obarzanek E, Benowitz NL, Hall SM, Klesges RC, Leischow S, Levin ED, Perkins KA, Spring B, Stitzer M, et al. PMID: 1396498.
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Misclassification of smoking status by self-reported cigarette consumption. Am Rev Respir Dis. 1992 Jan; 145(1):53-7. Pérez-Stable EJ, Marín G, Marín BV, Benowitz NL. PMID: 1731599.
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Nicotine replacement therapy during pregnancy. JAMA. 1991 Dec 11; 266(22):3174-7. Benowitz NL. PMID: 1956108.
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Basic and clinical psychopharmacology of nicotine. Clin Chest Med. 1991 Dec; 12(4):681-99. Le Houezec J, Benowitz NL. PMID: 1747987.
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Nicotine and coronary heart disease. Trends Cardiovasc Med. 1991 Dec; 1(8):315-21. Benowitz NL. PMID: 21239286.
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Poisoning due to calcium antagonists. Experience with verapamil, diltiazem and nifedipine. Drug Saf. 1991 Nov-Dec; 6(6):408-30. Pearigen PD, Benowitz NL. PMID: 1793522.
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Nicotine metabolism in humans. Clin Pharmacol Ther. 1991 Oct; 50(4):462-4. Benowitz NL, Jacob P. PMID: 1914383.
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Stable isotope method for studying transdermal drug absorption: the nicotine patch. Clin Pharmacol Ther. 1991 Sep; 50(3):286-93. Benowitz NL, Chan K, Denaro CP, Jacob P. PMID: 1914363.
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Amiloride improves hemodynamics in patients with chronic congestive heart failure treated with chronic digoxin and diuretics. Cardiovasc Drugs Ther. 1991 Aug; 5(4):719-25. Cheitlin MD, Byrd R, Benowitz N, Liu E, Modin G. PMID: 1888694.
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Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3',3'-d2 in humans. Biol Mass Spectrom. 1991 May; 20(5):247-52. Jacob P, Yu L, Wilson M, Benowitz NL. PMID: 1883864.
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Pharmacodynamics of nicotine: implications for rational treatment of nicotine addiction. Br J Addict. 1991 May; 86(5):495-9. Benowitz NL. PMID: 1859911.
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Disposition kinetics and metabolism of nicotine-1'-N-oxide in rabbits. Drug Metab Dispos. 1991 May-Jun; 19(3):667-72. Duan MJ, Yu L, Savanapridi C, Jacob P, Benowitz NL. PMID: 1680635.
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Stable isotope studies of nicotine kinetics and bioavailability. Clin Pharmacol Ther. 1991 Mar; 49(3):270-7. Benowitz NL, Jacob P, Denaro C, Jenkins R. PMID: 2007322.
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Elevated nicotine levels in cervical lavages from passive smokers. Am J Public Health. 1991 Mar; 81(3):378-9. Jones CJ, Schiffman MH, Kurman R, Jacob P, Benowitz NL. PMID: 1994747; PMCID: PMC1405010.
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Effects of caffeine with repeated dosing. Eur J Clin Pharmacol. 1991; 40(3):273-8. Denaro CP, Brown CR, Jacob P, Benowitz NL. PMID: 2060564.
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Poisoning due to class IA antiarrhythmic drugs. Quinidine, procainamide and disopyramide. Drug Saf. 1990 Nov-Dec; 5(6):393-420. Kim SY, Benowitz NL. PMID: 2285495.
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Nicotine metabolism in nonsmokers. Clin Pharmacol Ther. 1990 Oct; 48(4):473-4. Benowitz NL, Jacob P. PMID: 2225708.
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Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone. N Engl J Med. 1990 Sep 20; 323(12):776-82. Medina I, Mills J, Leoung G, Hopewell PC, Lee B, Modin G, Benowitz N, Wofsy CB. PMID: 2392131.
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Apparent underreporting of cigarette consumption among Mexican American smokers. Am J Public Health. 1990 Sep; 80(9):1057-61. Pérez-Stable EJ, Marín BV, Marín G, Brody DJ, Benowitz NL. PMID: 2382741; PMCID: PMC1404846.
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Intravenous nicotine replacement suppresses nicotine intake from cigarette smoking. J Pharmacol Exp Ther. 1990 Sep; 254(3):1000-5. Benowitz NL, Jacob P. PMID: 2203896.
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Dose-dependency of caffeine metabolism with repeated dosing. Clin Pharmacol Ther. 1990 Sep; 48(3):277-85. Denaro CP, Brown CR, Wilson M, Jacob P, Benowitz NL. PMID: 2401126.
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Cocaine. Emerg Med Clin North Am. 1990 Aug; 8(3):481-93. Mueller PD, Benowitz NL, Olson KR. PMID: 2201516.
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Synthesis of (3'R,5'S)-trans-3'-hydroxycotinine, a major metabolite of nicotine. Metabolic formation of 3'-hydroxycotinine in humans is highly stereoselective. J Med Chem. 1990 Jul; 33(7):1888-91. Jacob P, Shulgin AT, Benowitz NL. PMID: 2362266.
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Diagnosis and management of pheochromocytoma. Hosp Pract (Off Ed). 1990 Jun 15; 25(6):163-70, 173-4, 177. Benowitz NL. PMID: 2112143.
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Effect of chronic caffeine administration on monoamine and monoamine metabolite concentrations in rat brain. Neuropharmacology. 1990 Jun; 29(6):599-602. Kirch DG, Taylor TR, Gerhardt GA, Benowitz NL, Stephen C, Wyatt RJ. PMID: 2385331.
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Influence of race, tobacco use, and caffeine use on the relation between blood pressure and blood lead concentration. Am J Epidemiol. 1990 May; 131(5):845-54. Sharp DS, Benowitz NL, Osterloh JD, Becker CE, Smith AH, Syme SL. PMID: 2321627.
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Arterial-venous differences in plasma concentrations of nicotine after cigarette smoking. JAMA. 1990 Apr 18; 263(15):2049-50. Henningfield JE, London ED, Benowitz NL. PMID: 2319665.
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Nicotine exposure among nondependent smokers. Arch Gen Psychiatry. 1990 Apr; 47(4):333-6. Shiffman S, Fischer LB, Zettler-Segal M, Benowitz NL. PMID: 2322084.
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Determination of nornicotine in smokers' urine by gas chromatography following reductive alkylation to N'-propylnornicotine. J Chromatogr. 1990 Feb 23; 525(2):349-57. Zhang Y, Jacob P, Benowitz NL. PMID: 2329163.
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Pheochromocytoma. Adv Intern Med. 1990; 35:195-219. Benowitz NL. PMID: 2405593.
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Pharmacoepidemiology of the effect of caffeine on blood pressure. Clin Pharmacol Ther. 1990 Jan; 47(1):57-60. Sharp DS, Benowitz NL. PMID: 2295220.
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Clinical pharmacology of inhaled drugs of abuse: implications in understanding nicotine dependence. NIDA Res Monogr. 1990; 99:12-29. Benowitz NL. PMID: 2267009.
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Pharmacokinetic considerations in understanding nicotine dependence. Ciba Found Symp. 1990; 152:186-200; discussion 200-9. Benowitz NL. PMID: 2209254.
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Cocaine smokers excrete a pyrolysis product, anhydroecgonine methyl ester. J Toxicol Clin Toxicol. 1990; 28(1):121-5. Jacob P, Jones RT, Benowitz NL, Shulgin AT, Lewis ER, Elias-Baker BA. PMID: 2381018.
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Clinical pharmacology of caffeine. Annu Rev Med. 1990; 41:277-88. Benowitz NL. PMID: 2184730.
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Caffeine and cigarette smoking: behavioral, cardiovascular, and metabolic interactions. Pharmacol Biochem Behav. 1989 Nov; 34(3):565-70. Brown CR, Benowitz NL. PMID: 2623013.
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Poisoning due to class 1B antiarrhythmic drugs. Lignocaine, mexiletine and tocainide. Med Toxicol Adverse Drug Exp. 1989 Nov-Dec; 4(6):412-28. Denaro CP, Benowitz NL. PMID: 2513464.
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Inverse relation between serum cotinine concentration and blood pressure in cigarette smokers. Circulation. 1989 Nov; 80(5):1309-12. Benowitz NL, Sharp DS. PMID: 2805267.
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Effects of passive smoking on theophylline clearance. Clin Pharmacol Ther. 1989 Oct; 46(4):399-407. Matsunga SK, Plezia PM, Karol MD, Katz MD, Camilli AE, Benowitz NL. PMID: 2791443.
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Sulfonium salts as derivatizing agents. 2. Determination of theophylline in plasma by automated gas chromatography. J Chromatogr. 1989 Sep 29; 494:109-17. Lee BL, Jacob P, Benowitz NL. PMID: 2584311.
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Toxicologic causes of acute abdominal disorders. Emerg Med Clin North Am. 1989 Aug; 7(3):667-82. Mueller PD, Benowitz NL. PMID: 2663462.
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Daily use of smokeless tobacco: systemic effects. Ann Intern Med. 1989 Jul 15; 111(2):112-6. Benowitz NL, Jacob P, Yu L. PMID: 2742246.
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Food and nicotine metabolism. Pharmacol Biochem Behav. 1989 Jul; 33(3):621-5. Lee BL, Jacob P, Jarvik ME, Benowitz NL. PMID: 2587604.
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Health and public policy implications of the "low yield" cigarette. N Engl J Med. 1989 Jun 15; 320(24):1619-21. Benowitz NL. PMID: 2725602.
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Diabetic patients and hepatic drug metabolism. Clin Pharmacol Ther. 1989 Jun; 45(6):695-6. Denaro C, Benowitz N. PMID: 2731408.
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Persistent increase in caffeine concentrations in people who stop smoking. BMJ. 1989 Apr 22; 298(6680):1075-6. Benowitz NL, Hall SM, Modin G. PMID: 2497897; PMCID: PMC1836474.
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Dapsone, trimethoprim, and sulfamethoxazole plasma levels during treatment of Pneumocystis pneumonia in patients with the acquired immunodeficiency syndrome (AIDS). Evidence of drug interactions. Ann Intern Med. 1989 Apr 15; 110(8):606-11. Lee BL, Medina I, Benowitz NL, Jacob P, Wofsy CB, Mills J. PMID: 2784648.
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Effects of nicotine gum and tobacco smoking on human avoidance responding. Pharmacol Biochem Behav. 1989 Mar; 32(3):677-81. Cherek DR, Bennett RH, Kelly TH, Steinberg JL, Benowitz NL. PMID: 2740422.
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Changes in food intake and activity after quitting smoking. J Consult Clin Psychol. 1989 Feb; 57(1):81-6. Hall SM, McGee R, Tunstall C, Duffy J, Benowitz N. PMID: 2925977.
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Nicotine gum and theophylline metabolism. Biomed Pharmacother. 1989; 43(1):1-3. Benowitz NL, Lee BL, Jacob P. PMID: 2730948.
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Nicotine dependence and tolerance in man: pharmacokinetic and pharmacodynamic investigations. Prog Brain Res. 1989; 79:279-87. Benowitz NL, Porchet H, Jacob P. PMID: 2587748.
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Are smokers trying to stop and smokers not trying to stop the same experimental model? NIDA Res Monogr. 1989; 95:366-7. Sachs DP, Benowitz N. PMID: 2701304.
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Drug therapy. Pharmacologic aspects of cigarette smoking and nicotine addiction. N Engl J Med. 1988 11 17; 319(20):1318-30. Benowitz NL. PMID: 3054551.
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Sodium intake from smokeless tobacco. N Engl J Med. 1988 Sep 29; 319(13):873-4. Benowitz NL. PMID: 3412420.
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Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum. Clin Pharmacol Ther. 1988 Jul; 44(1):23-8. Benowitz NL, Porchet H, Sheiner L, Jacob P. PMID: 3391001.
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Nicotine and smokeless tobacco. CA Cancer J Clin. 1988 Jul-Aug; 38(4):244-7. Benowitz NL. PMID: 3135084.
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Cotinine in the serum, saliva, and urine of nonsmokers, passive smokers, and active smokers. Am J Public Health. 1988 Jun; 78(6):699-701. Wall MA, Johnson J, Jacob P, Benowitz NL. PMID: 3369604; PMCID: PMC1350288.
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Elimination of cotinine from body fluids: implications for noninvasive measurement of tobacco smoke exposure. Am J Public Health. 1988 Jun; 78(6):696-8. Jarvis MJ, Russell MA, Benowitz NL, Feyerabend C. PMID: 3369603; PMCID: PMC1350287.
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Disposition kinetics of nicotine and cotinine enantiomers in rabbits and beagle dogs. J Pharm Sci. 1988 May; 77(5):396-400. Jacob P, Benowitz NL, Copeland JR, Risner ME, Cone EJ. PMID: 3411460.
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Recent studies of nicotine metabolism in humans. Pharmacol Biochem Behav. 1988 May; 30(1):249-53. Jacob P, Benowitz NL, Shulgin AT. PMID: 3174750.
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Pheochromocytoma--recent advances in diagnosis and treatment. West J Med. 1988 May; 148(5):561-7. Benowitz NL. PMID: 3176460; PMCID: PMC1026174.
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Changes in rate and pattern of caffeine metabolism after cigarette abstinence. Clin Pharmacol Ther. 1988 May; 43(5):488-91. Brown CR, Jacob P, Wilson M, Benowitz NL. PMID: 3365914.
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Nicotine gum: chew rate, subjective effects and plasma nicotine. Pharmacol Biochem Behav. 1988 Apr; 29(4):747-51. Nemeth-Coslett R, Benowitz NL, Robinson N, Henningfield JE. PMID: 3413200.
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Effects of the stereoisomers of nicotine and nornicotine on schedule-controlled responding and physiological parameters of dogs. J Pharmacol Exp Ther. 1988 Mar; 244(3):807-13. Risner ME, Cone EJ, Benowitz NL, Jacob P. PMID: 3252033.
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Toxicity of nicotine: implications with regard to nicotine replacement therapy. Prog Clin Biol Res. 1988; 261:187-217. Benowitz NL. PMID: 3289005.
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Cardiovascular effects of smoking in patients with ischemic heart disease. Chest. 1988 Jan; 93(1):14-9. Myers MG, Benowitz NL, Dubbin JD, Haynes RB, Sole MJ. PMID: 3335145.
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Pharmacodynamic model of tolerance: application to nicotine. J Pharmacol Exp Ther. 1988 Jan; 244(1):231-6. Porchet HC, Benowitz NL, Sheiner LB. PMID: 3336000.
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Identification and quantitative analysis of cotinine-N-oxide in human urine. J Chromatogr. 1987 Dec 25; 423:365-72. Shulgin AT, Jacob P, Benowitz NL, Lau D. PMID: 3443673.
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Brain phenobarbital uptake during prolonged status epilepticus. J Cereb Blood Flow Metab. 1987 Dec; 7(6):783-8. Simon RP, Copeland JR, Benowitz NL, Jacob P, Bronstein J. PMID: 3693434.
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Electrophysiologic effects of cigarette smoking in patients with and without chronic beta-blocker therapy. Am J Cardiol. 1987 Nov 01; 60(13):1078-82. Peters RW, Benowitz NL, Valenti S, Modin G, Fisher ML. PMID: 2890291.
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Apparent tolerance to the acute effect of nicotine results in part from distribution kinetics. J Clin Invest. 1987 Nov; 80(5):1466-71. Porchet HC, Benowitz NL, Sheiner LB, Copeland JR. PMID: 3680508; PMCID: PMC442405.
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Spontaneous cigarette brand switching: consequences for nicotine and carbon monoxide exposure. Am J Public Health. 1987 Sep; 77(9):1191-4. Lynch CJ, Benowitz NL. PMID: 3618852; PMCID: PMC1647023.
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The effect of cigarette smoking on penile erection. J Urol. 1987 Aug; 138(2):438-41. Juenemann KP, Lue TF, Luo JA, Benowitz NL, Abozeid M, Tanagho EA. PMID: 3599273.
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Determination of benzoylecgonine and cocaine in biologic fluids by automated gas chromatography. J Chromatogr. 1987 Jul 03; 417(2):277-86. Jacob P, Elias-Baker BA, Jones RT, Benowitz NL. PMID: 3654881.
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Prolonged absorption with development of tolerance to toxic effects after cutaneous exposure to nicotine. Clin Pharmacol Ther. 1987 Jul; 42(1):119-20. Benowitz NL, Lake T, Keller KH, Lee BL. PMID: 3595064.
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Influence of tobacco abstinence on the disposition kinetics and effects of nicotine. Clin Pharmacol Ther. 1987 Apr; 41(4):474-9. Lee BL, Benowitz NL, Jacob P. PMID: 3829584.
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Determinants of nicotine intake while chewing nicotine polacrilex gum. Clin Pharmacol Ther. 1987 Apr; 41(4):467-73. Benowitz NL, Jacob P, Savanapridi C. PMID: 3829583.
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Cigarette abstinence, nicotine gum, and theophylline disposition. Ann Intern Med. 1987 Apr; 106(4):553-5. Lee BL, Benowitz NL, Jacob P. PMID: 3826954.
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Mouth versus deep airways absorption of nicotine in cigarette smokers. Pharmacol Biochem Behav. 1986 Dec; 25(6):1181-4. Gori GB, Benowitz NL, Lynch CJ. PMID: 3809219.
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Influence of smoking fewer cigarettes on exposure to tar, nicotine, and carbon monoxide. N Engl J Med. 1986 Nov 20; 315(21):1310-3. Benowitz NL, Jacob P, Kozlowski LT, Yu L. PMID: 3773954.
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Hyperthermia associated with drug intoxication. Crit Care Med. 1986 Nov; 14(11):964-9. Rosenberg J, Pentel P, Pond S, Benowitz N, Olson K. PMID: 3769509.
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Additive cardiovascular effects of nicotine and ethanol. Clin Pharmacol Ther. 1986 Oct; 40(4):420-4. Benowitz NL, Jones RT, Jacob P. PMID: 3757405.
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Determination of nicotine N-oxide by gas chromatography following thermal conversion to 2-methyl-6-(3-pyridyl)tetrahydro-1,2-oxazine. Anal Chem. 1986 Sep; 58(11):2218-21. Jacob P, Benowitz NL, Yu L, Shulgin AT. PMID: 3766974.
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Reduced tar, nicotine, and carbon monoxide exposure while smoking ultralow- but not low-yield cigarettes. JAMA. 1986 Jul 11; 256(2):241-6. Benowitz NL, Jacob P, Yu L, Talcott R, Hall S, Jones RT. PMID: 3723711.
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Tricyclic antidepressant poisoning. Management of arrhythmias. Med Toxicol. 1986 Mar-Apr; 1(2):101-21. Pentel PR, Benowitz NL. PMID: 3784839.
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Status epilepticus: divergence of sympathetic activity and cardiovascular response. Ann Neurol. 1986 Feb; 19(2):197-9. Benowitz NL, Simon RP, Copeland JR. PMID: 3963763.
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Nicotine and smoking relapse. Health Psychol. 1986; 5 Suppl:41-51. Pomerleau OF, Bell CS, Benowitz NL, Best JA, Glassman A, Russell M, Russell P, Schneider NG. PMID: 3582324.
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Clinical pharmacology of nicotine. Annu Rev Med. 1986; 37:21-32. Benowitz NL. PMID: 3518606.
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Theophylline overdose: acute single ingestion versus chronic repeated overmedication. Am J Emerg Med. 1985 Sep; 3(5):386-94. Olson KR, Benowitz NL, Woo OF, Pond SM. PMID: 4041188.
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Influence of the blood-brain pH gradient on brain phenobarbital uptake during status epilepticus. J Pharmacol Exp Ther. 1985 Sep; 234(3):830-5. Simon RP, Benowitz N, Hedlund R, Copeland J. PMID: 4032292.
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Nicotine renal excretion rate influences nicotine intake during cigarette smoking. J Pharmacol Exp Ther. 1985 Jul; 234(1):153-5. Benowitz NL, Jacob P. PMID: 4009497.
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Atrioventricular conduction block caused by phenylpropanolamine. JAMA. 1985 May 10; 253(18):2646-7. Woo OF, Benowitz NL, Bialy FW, Wengert JW. PMID: 3989943.
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Propranolol antagonism of phenylpropanolamine-induced hypertension. Clin Pharmacol Ther. 1985 May; 37(5):488-94. Pentel PR, Asinger RW, Benowitz NL. PMID: 3987172.
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Nicotine gum and behavioral treatment in smoking cessation. J Consult Clin Psychol. 1985 Apr; 53(2):256-8. Hall SM, Tunstall C, Rugg D, Jones RT, Benowitz N. PMID: 3998252.
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Altered methadone pharmacokinetics in methadone-maintained pregnant women. J Pharmacol Exp Ther. 1985 Apr; 233(1):1-6. Pond SM, Kreek MJ, Tong TG, Raghunath J, Benowitz NL. PMID: 3981450.
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Trazodone-oral cocaine interactions. Arch Gen Psychiatry. 1984 Sep; 41(9):895-9. Rowbotham MC, Jones RT, Benowitz NL, Jacob P. PMID: 6380447.
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Two-year efficacy and safety of rapid smoking therapy in patients with cardiac and pulmonary disease. J Consult Clin Psychol. 1984 Aug; 52(4):574-81. Hall RG, Sachs DP, Hall SM, Benowitz NL. PMID: 6470283.
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Ion-pair extraction of thiocyanate from plasma and its gas chromatographic determination using on-column alkylation. Anal Chem. 1984 Aug; 56(9):1692-5. Jacob P, Savanapridi C, Yu L, Wilson M, Shulgin AT, Benowitz NL, Elias-Baker BA, Hall SM, Herning RI, Jones RT, et al. PMID: 6486450.
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Environmental and drug-induced hyperthermia. Pathophysiology, recognition, and management. Emerg Med Clin North Am. 1984 Aug; 2(3):459-74. Olson KR, Benowitz NL. PMID: 6534737.
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Nicotine and carbon monoxide intake from high- and low-yield cigarettes. Clin Pharmacol Ther. 1984 Aug; 36(2):265-70. Benowitz NL, Jacob P. PMID: 6744784.
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Influence of nicotine on cardiovascular and hormonal effects of cigarette smoking. Clin Pharmacol Ther. 1984 Jul; 36(1):74-81. Benowitz NL, Kuyt F, Jacob P. PMID: 6734053.
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Efficacy and mechanism of action of sodium bicarbonate in the treatment of desipramine toxicity in rats. J Pharmacol Exp Ther. 1984 Jul; 230(1):12-9. Pentel P, Benowitz N. PMID: 6086872.
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Pharmacokinetic and pharmacodynamic considerations in drug therapy of cardiac emergencies. Clin Pharmacokinet. 1984 Jul-Aug; 9(4):273-308. Pentel P, Benowitz N. PMID: 6380870.
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Blood cotinine levels as indicators of smoking treatment outcome. Clin Pharmacol Ther. 1984 Jun; 35(6):810-4. Hall SM, Herning RI, Jones RT, Benowitz NL, Jacob P. PMID: 6734033.
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Antihypertensive therapy with diltiazem and comparison with hydrochlorothiazide. Am J Cardiol. 1984 Jun 01; 53(11):1588-92. Inouye IK, Massie BM, Benowitz N, Simpson P, Loge D. PMID: 6375339.
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Daily intake of nicotine during cigarette smoking. Clin Pharmacol Ther. 1984 Apr; 35(4):499-504. Benowitz NL, Jacob P. PMID: 6705448.
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Determination of cocaine in plasma by automated gas chromatography. J Chromatogr. 1984 Mar 09; 306:173-81. Jacob P, Elias-Baker BA, Jones RT, Benowitz NL. PMID: 6715457.
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Motor paralysis increases brain uptake of lidocaine during status epilepticus. Neurology. 1984 Mar; 34(3):384-7. Simon RP, Benowitz NL, Culala S. PMID: 6538283.
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Changes in plasma catecholamines after tonic-clonic seizures. Neurology. 1984 Feb; 34(2):255-7. Simon RP, Aminoff MJ, Benowitz NL. PMID: 6538024.
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Monotherapy in mild to moderate hypertension: comparison of hydrochlorothiazide, propranolol and prazosin. Am J Cardiol. 1984 Jan 27; 53(3):24A-28A. Inouye I, Massie B, Benowitz N, Simpson P, Loge D, Topic N. PMID: 6320622.
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Unchanged absorption of digoxin tablets in patients with cardiac failure. Pharmacology. 1984; 28(2):90-4. Meister W, Benowitz NL, Benet LZ. PMID: 6709691.
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Benefit of hemoperfusion in acute theophylline intoxication. J Toxicol Clin Toxicol. 1984; 22(5):411-24. Woo OF, Pond SM, Benowitz NL, Olson KR. PMID: 6530699.
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Relationship of duration of analgesia to opioid pharmacokinetic variables. Brain Res. 1983 Dec 19; 289(1-2):391-4. Levine J, Gordon NC, Poole T, Benowitz N. PMID: 6318904.
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(--)-alpha-Acetylmethadol effects on alcohol and diazepam use, sexual function and cardiac function. Drug Alcohol Depend. 1983 Dec; 12(4):323-32. Hargreaves WA, Tyler J, Weinberg JA, Sorensen JL, Benowitz N. PMID: 6671416.
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Cotinine disposition and effects. Clin Pharmacol Ther. 1983 Nov; 34(5):604-11. Benowitz NL, Kuyt F, Jacob P, Jones RT, Osman AL. PMID: 6627820.
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Management of cocaine poisoning. Ann Emerg Med. 1983 Oct; 12(10):655-7. Olson K, Benowitz NL, Pentel P. PMID: 6625275.
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Normotensive pheochromocytoma. Pharmacologic, paraneoplastic and anesthetic considerations. West J Med. 1983 Aug; 139(2):221-5. Kirby BD, Ham J, Fairley HB, Benowitz N, Schambelan M. PMID: 6636736; PMCID: PMC1010945.
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Smokers of low-yield cigarettes do not consume less nicotine. N Engl J Med. 1983 Jul 21; 309(3):139-42. Benowitz NL, Hall SM, Herning RI, Jacob P, Jones RT, Osman AL. PMID: 6866013.
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Treatment of theophylline overdose. JAMA. 1983 Jun 17; 249(23):3176. Olson KR, Pond SM, Benowitz NL, Becker CE. PMID: 6854843.
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Passive absorption of nicotine in airline flight attendants. N Engl J Med. 1983 May 05; 308(18):1105. Foliart D, Benowitz NL, Becker CE. PMID: 6835330.
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Late complications of tricyclic antidepressant overdose. West J Med. 1983 Mar; 138(3):423-4. Pentel P, Olson KR, Becker CE, Benowitz N. PMID: 6858131; PMCID: PMC1021501.
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How a cigarette is smoked determines blood nicotine levels. Clin Pharmacol Ther. 1983 Jan; 33(1):84-90. Herning RI, Jones RT, Benowitz NL, Mines AH. PMID: 6848303.
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The use of biologic fluid samples in assessing tobacco smoke consumption. NIDA Res Monogr. 1983; 48:6-26. Benowitz NL. PMID: 6443145.
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Circadian blood nicotine concentrations during cigarette smoking. Clin Pharmacol Ther. 1982 Dec; 32(6):758-64. Benowitz NL, Kuyt F, Jacob P. PMID: 7140139.
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Massive catecholamine release from caffeine poisoning. JAMA. 1982 Sep 03; 248(9):1097-8. Benowitz NL, Osterloh J, Goldschlager N, Kaysen G, Pond S, Forhan S. PMID: 7109204.
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Interindividual variability in the metabolism and cardiovascular effects of nicotine in man. J Pharmacol Exp Ther. 1982 May; 221(2):368-72. Benowitz NL, Jacob P, Jones RT, Rosenberg J. PMID: 7077531.
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Lack of effect of diazepam on methadone metabolism in methadone-maintained addicts. Clin Pharmacol Ther. 1982 Feb; 31(2):139-43. Pond SM, Tong TG, Benowitz NL, Jacob P, Rigod J. PMID: 7056020.
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Gas chromatographic analysis of meperidine and normeperidine: determination in blood after a single dose of meperidine. J Pharm Sci. 1982 Feb; 71(2):166-8. Jacob P, Rigod JF, Pond SM, Benowitz NL. PMID: 7062237.
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Increased brain uptake of lidocaine during bicuculline-induced status epilepticus in rats. Neurology. 1982 Feb; 32(2):196-9. Simon RP, Benowitz NL, Bronstein J, Jacob P. PMID: 7198745.
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Acute vasodilator therapy increases renal clearance of digoxin in patients with congestive heart failure. Circulation. 1981 Nov; 64(5):973-6. Cogan JJ, Humphreys MH, Carlson CJ, Benowitz NL, Rapaport E. PMID: 7285311.
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Determination of methadone and its primary metabolite in biologic fluids using gas chromatography with nitrogen-phosphorus detection. J Anal Toxicol. 1981 Nov-Dec; 5(6):292-5. Jacob P, Rigod JF, Pond SM, Benowitz NL. PMID: 7339214.
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Presystemic metabolism of meperidine to normeperidine in normal and cirrhotic subjects. Clin Pharmacol Ther. 1981 Aug; 30(2):183-8. Pond SM, Tong T, Benowitz NL, Jacob P, Rigod J. PMID: 7249503.
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Plasma nicotine and cotinine concentrations in habitual smokeless tobacco users. Clin Pharmacol Ther. 1981 Aug; 30(2):201-9. Gritz ER, Baer-Weiss V, Benowitz NL, Van Vunakis H, Jarvik ME. PMID: 7195786.
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Clinical relevance of cannabis tolerance and dependence. J Clin Pharmacol. 1981 Aug-Sep; 21(S1):143S-152S. Jones RT, Benowitz NL, Herning RI. PMID: 6271820.
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Cardiovascular and metabolic considerations in prolonged cannabinoid administration in man. J Clin Pharmacol. 1981 Aug-Sep; 21(S1):214S-223S. Benowitz NL, Jones RT. PMID: 6271827.
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Pharmacokinetics of drug overdose. Clin Pharmacokinet. 1981 May-Jun; 6(3):161-92. Rosenberg J, Benowitz NL, Pond S. PMID: 7016383.
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Phenytoin-induced methadone withdrawal. Ann Intern Med. 1981 Mar; 94(3):349-51. Tong TG, Pond SM, Kreek MJ, Jaffery NF, Benowitz NL. PMID: 7224382.
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The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys. J Pharmacol Exp Ther. 1981 Feb; 216(2):247-53. Fredericks AB, Benowitz NL, Savanapridi CY. PMID: 6257883.
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Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids. J Chromatogr. 1981 Jan 02; 222(1):61-70. Jacob P, Wilson M, Benowitz NL. PMID: 6783675.
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Diabetes mellitus and orthostatic hypotension resulting from ingestion of Vacor rat poison: endocrine and autonomic function studies. West J Med. 1981 Jan; 134(1):65-8. Peters KS, Tong TG, Kutz K, Benowitz NL. PMID: 7210664; PMCID: PMC1272465.
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Disposition kinetics and effects of intravenous nicotine. Clin Pharmacol Ther. 1980 Oct; 28(4):517-22. Rosenberg J, Benowitz NL, Jacob P, Wilson KM. PMID: 7408411.
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Enhanced bioavailability of pethidine and pentazocine in patients with cirrhosis of the liver. Aust N Z J Med. 1980 Oct; 10(5):515-9. Pond SM, Tong T, Benowitz NL, Jacob P. PMID: 6937164.
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Methadone-disulfiram interaction during methadone maintenance. J Clin Pharmacol. 1980 Aug-Sep; 20(8-9):506-13. Tong TG, Benowitz NL, Kreek MJ. PMID: 7430415.
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Metabolic and psychophysiologic studies of cannabidiol-hexobarbital interaction. Clin Pharmacol Ther. 1980 Jul; 28(1):115-20. Benowitz NL, Nguyen TL, Jones RT, Herning RI, Bachman J. PMID: 7389248.
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Dihydroergotamine treatment for orthostatic hypotension from Vacor rodenticide. Ann Intern Med. 1980 Mar; 92(3):387-8. Benowitz NL, Byrd R, Schambelan M, Rosenberg J, Roizen MF. PMID: 7356234.
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Resin hemoperfusion for ethchlorvynol. Ann Intern Med. 1980 Mar; 92(3):435-6. Benowitz NL, Rosenberg J, Pond S. PMID: 7356245.
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Resin hemoperfusion in ethychlorvynol overdose. Clin Pharmacol Ther. 1980 Feb; 27(2):236-42. Benowitz N, Abolin C, Tozer T, Rosenberg J, Rogers W, Pond S, Schoenfeld P, Humphreys M. PMID: 7353346.
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An abstinence syndrome following chronic administration of delta-9-terahydrocannabinol in rhesus monkeys. Psychopharmacology (Berl). 1980; 71(2):201-2. Fredericks AB, Benowitz NL. PMID: 6255508.
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Pharmacokinetics of haemoperfusion for drug overdose. Clin Pharmacokinet. 1979 Sep-Oct; 4(5):329-54. Pond S, Rosenberg J, Benowitz NL, Takki S. PMID: 389527.
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Effect of disulfiram on cognition, subjective response, and cortical-event-related potentials in nonalcoholic subjects. Alcohol Clin Exp Res. 1979 Jul; 3(3):223-9. Peeke SC, Prael AR, Herning RI, Rogers W, Benowitz NL, Jones RT. PMID: 384831.
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Diazepam kinetics in acute alcohol withdrawal. Clin Pharmacol Ther. 1979 Jun; 25(6):832-6. Pond SM, Phillips M, Benowitz NL, Galinsky RE, Tong TG, Becker CE. PMID: 445950.
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Cardiovascular effects of intravenous delta-9-tetrahydrocannabinol: autonomic nervous mechanisms. Clin Pharmacol Ther. 1979 Apr; 25(4):440-6. Benowitz NL, Rosenberg J, Rogers W, Bachman J, Jones RT. PMID: 428189.
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Effect of disulfiram on adrenergic function. Clin Pharmacol Ther. 1979 Apr; 25(4):469-77. Rogers WK, Benowitz NL, Wilson KM, Abbott JA. PMID: 106999.
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Dissociation of autonomic and cognitive effects of THC in man. Psychopharmacology (Berl). 1979 Mar 22; 61(2):171-5. Bachman JA, Benowitz NL, Herning RI, Jones RT. PMID: 108734.
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Peritoneal clearance and total body elimination of vancomycin during chronic intermittent peritoneal dialysis. Clin Nephrol. 1979 Mar; 11(3):129-32. Ayus JC, Eneas JF, Tong TG, Benowitz NL, Schoenfeld PY, Hadley KL, Becker CE, Humphreys MH. PMID: 436339.
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Hypertensive emergencies. Med Clin North Am. 1979 Jan; 63(1):127-40. Becker CE, Benowitz NL. PMID: 431188.
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Cardiopulmonary catastrophes in drug-overdosed patients. Med Clin North Am. 1979 Jan; 63(1):267-96. Benowitz NL, Rosenberg J, Becker CE. PMID: 431195.
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Clinical pharmacokinetics of lignocaine. Clin Pharmacokinet. 1978 May-Jun; 3(3):177-201. Benowitz NL, Meister W. PMID: 350470.
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Effects of delta-9-tetrahydrocannabinol on drug distribution and metabolism. Antipyrine, pentobarbital, and ethanol. Clin Pharmacol Ther. 1977 Sep; 22(3):259-68. Benowitz NL, Jones RT. PMID: 891094.
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Prolonged delta-9-tetrahydrocannabinol ingestion. Effects of sympathomimetic amines and autonomic blockades. Clin Pharmacol Ther. 1977 Mar; 21(3):336-42. Benowitz NL, Jones RT. PMID: 837652.
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Pharmacokinetics in patients with cardiac failure. Clin Pharmacokinet. 1976 Nov-Dec; 1(6):389-405. Benowitz NL, Meister W. PMID: 799548.
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Phytohemagglutinin-induced lymphocyte transformation in humans receiving delta9-tetrahydrocannabinol. Science. 1976 May 21; 192(4241):805-7. Lau RJ, Tubergen DG, Barr M, Domino EF, Benowitz N, Jones RT. PMID: 1265484.
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Depression of growth hormone and cortisol response to insulin-induced hypoglycemia after prolonged oral delta-9-tetrahydrocannabinol administration in man. J Clin Endocrinol Metab. 1976 May; 42(5):938-41. Benowitz NL, Jones RT, Lerner CB. PMID: 1270583.
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Gestational differences in lidocaine toxicity in the fetal lamb. Anesthesiology. 1976 Feb; 44(2):133-8. Teramo K, Benowitz N, Heymann MA, Rudolph AM. PMID: 1252020.
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Clinical studies of cannabis tolerance and dependence. Ann N Y Acad Sci. 1976; 282:221-39. Jones RT, Benowitz N, Bachman J. PMID: 798533.
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Phencyclidine poisoning. JAMA. 1975 Nov 03; 234(5):512-3. Tong TG, Benowitz NL, Becker CE, Forni PJ, Boerner U. PMID: 1242170.
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Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion. Clin Pharmacol Ther. 1975 Sep; 18(3):287-97. Benowitz NL, Jones RT. PMID: 1164818.
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Letter: "Post hoc" and hypoprothrombinemia. Ann Intern Med. 1975 Aug; 83(2):286-7. Galinsky RE, Forni PJ, McGuire GG, Tong TG, Benowitz N, Becker CE. PMID: 1147473.
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Lidocaine disposition kinetics in monkey and man. I. Prediction by a perfusion model. Clin Pharmacol Ther. 1974 Jul; 16(1):87-98. Benowitz N, Forsyth FP, Melmon KL, Rowland M. PMID: 4210516.
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Lidocaine disposition kinetics in monkey and man. II. Effects of hemorrhage and sympathomimetic drug administration. Clin Pharmacol Ther. 1974 Jul; 16(1):99-109. Benowitz N, Forsyth RP, Melmon KL, Rowland M. PMID: 4210517.
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Effects of lidocaine on heart rate, blood pressure, and electrocorticogram in fetal sheep. Am J Obstet Gynecol. 1974 Apr 01; 118(7):935-49. Teramo K, Benowitz N, Heymann MA, Kahanpää K, Siimes A, Rudolph AM. PMID: 4818426.
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Electrophysiologic effects of procaine amide in patients with intraventricular conduction delay. Circulation. 1974 Mar; 49(3):522-9. Scheinman MM, Weiss AN, Shafton E, Benowitz N, Rowland M. PMID: 4591547.
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Clinical applications of the pharmacokinetics of lidocaine. Cardiovasc Clin. 1974; 6(2):77-101. Benowitz NL. PMID: 4613465.
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Determination of lidocaine in blood and tissues. Anesthesiology. 1973 Dec; 39(6):639-41. Benowitz N, Rowland M. PMID: 4202543.
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Calcium binding to phosphoprotein in estrogenized rooster plasma studied by density-gradient centrifugation. Proc Soc Exp Biol Med. 1968 Oct; 129(1):46-50. Benowitz NL, Terepka AR. PMID: 5686540.
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