Research | UConn School of Pharmacy and Pharmaceutical Sciences | University of Connecticut
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UConn
School of Pharmacy and Pharmaceutical Sciences
School of Pharmacy and Pharmaceutical Sciences
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UConn A-Z
UConn's School of Pharmacy allows students to customize their studies to align with their research interests, collaborate with world renowned faculty, and pursue specialized training to complement their core studies. Whether you are interested in a Pharmaceutical Sciences or Pharmacy Practice path you will find innovative work being done in our labs, and collaborative work.
Research and Opportunities
Pharmaceutical Sciences Faculty Labs and Research
Always moving the needle on pharmaceutics, pharmacology and toxicology, medical chemistry. Every member of the UConn School of Pharmacy's Department of Pharmaceutical Sciences is involved in scientific research.
Current Research Areas
Drug Design & Discovery |
DDD
Drug Metabolism & Metabolomics |
DMM
Behavioral & Molecular Pharmacology |
BMP
Mechanistic Toxicology |
MT
Nanomedicine & Drug Delivery |
NDD
Epigenetics & Noncoding RNA |
EN
Pharmaceutical Technology & Manufacturing |
PTM
Biomedical & Molecular Imaging |
BMI
Faculty Research
(organized by foci)
Pharmaceutics
Raman Bahal
NDD
PTM
Research Focus:
New delivery strategies for synthetic nucleic acid analogues, develop novel gene correction based reagents. Selectively target oncogenic microRNAs for cancer therapy, and other microRNAs for treating genetic metabolic disorders.
Bahal Lab
Robin Bogner
PTM
Research Focus:
Freeze-drying process modeling and optimization, formulation and performance of pharmaceutical solids -- both freeze-dried parenterals and oral dosage forms, amorphous drug solubility, reconstitution of lyophilized protein therapeutics, stability of compounded preparations.
Diane Burgess
NDD
PTM
Research Focus:
Drug delivery (microspheres, nanoparticles, liposomes, emulsions, hydrogels); in vitro and in vivo performance testing; continuous manufacturing of complex parenterals; implantable sensors for metabolic monitoring.
Burgess Lab
Bodhi Chaudhuri
NDD
PTM
Research Focus:
Powder Technology, Multi-Scale Modeling of Materials, Manufacturing Processes, and Drug Delivery, Molecular Modeling (MD), Discrete Element Method (DEM), Computational Fluid Dynamics (CFD), Artificial Intelligence/Machine Learning (AI/ML), Additive Manufacturing (3D Printing), and Continuous Manufacturing of pharmaceuticals.
Chaudhuri Lab
Na Li
NDD
PTM
Research Focus:
Oral drug delivery, enabling formulation and process development of poorly-soluble drugs, interactions with the human gastrointestinal environment including the gut microbiome.
Li Lab
Xiuling Lu
NDD
PTM
BMI
Research Focus:
Formulation development, characterization and assessment, drug delivery systems, multifunctional nanocarriers for improved cancer therapy, theranostic nanomedicine.
Lu Lab
Pharmacology and Toxicology
Brian Aneskievich
BMP
Research Focus:
Molecular pharmacology of cell membrane and nuclear receptor signaling control over regulation of gene expression relevant to chronic inflammatory diseases, defects in differentiation, and cancer proliferation.
José Manautou
DMM
MT
Research Focus:
Identification and characterization of novel genetic determinants of susceptibility to chemical hepatotoxicity, regulation of liver transporters, chemical models of hepatoprotection.
Theodore Rasmussen
DMM
MT
EN
Research Focus:
Personalized medicine, stem cell research, and epigenetics as related to cholesterol dysfunction, birth defects, and reproductive biology.
Gregory Sartor
DMM
BMP
EN
DDD
Research Focus:
Animal models of drug addiction; epigenetics, cell type-specific analysis, and drug discovery.
L. Cody Smith
MT
BMP
Research Focus:
Air pollution and respiratory system toxicology, immunology and inflammatory signaling mechanisms, sex steroid signaling and sex differences in inflammation, mouse models.
Xiaobo Zhong
EN
BMI
Research Focus:
Mechanistic roles of long non-coding RNAs in postnatal liver maturation, alteration of drug metabolism in adults by drug exposure at early life, interindividual variations on drug metabolism and personalized medicine.
Medicinal Chemistry
Chat Abeywickrama
BMI
DDD
Research Focus:
Development of small-molecule fluorescent dyes for biomedical imaging and diagnostic applications, fluorophore-guided drug delivery and trafficking, and (bio)chemical sensing dyes.
M. Kyle Hadden
DDD
Research Focus:
Early stage drug development focusing on the design, synthesis, and evaluation of small molecules as therapeutic agents for the treatment of cancer.
Hadden Lab
Hunmin Jung
DDD
Research Focus:
Structure-guided development of: 1. anticancer agents targeting DNA lesion repair and
de novo
nucleotide biosynthesis pathways; 2.  modulators that inhibit or enhance the incorporation of non-natural nucleotides into DNA or RNA; 3. antidiabetic agents/biomarkers targeting glucose sensing transcription factors; 4. antibacterial/antiviral agents targeting DNA repair/bypass and nucleotide metabolism. Jung Lab website under development.
Jung Lab
Olga Vinogradova
DDD
Research Focus:
Structural Biology, Protein-Protein/Protein-Ligand Interactions, Rational Drug Design, Integral Membrane Proteins and Across-membrane Signal Transduction, Nanodiscs, NMR.
Vinogradova Lab
Andrew Wiemer
DDD
BMP
Research Focus:
Discovery of drugs and drug targets related to cancer and immunology.
Wiemer Lab
Dennis Wright
DDD
Research Focus:
The design, synthesis and development of small molecule therapeutics primarily for the treatment of infectious disease and cancer.
Pharmaceutical Sciences Faculty Publications
Pharmaceutical Sciences Faculty Publications
Pharmacy Practice Collaborative Research Groups
UConn School of Pharmacy faculty influential advocates for new models of care. Some of the concerns we have addressed include problems associated with polypharmacy, medication errors, and patient compliance. Our knowledge of the industry comes from depth and breadth of experience. Our alliances, research and leadership roles translate to industry change to positively benefits communities, nation and world wide.
Current Research Groups
UConn Health Outcomes, Policy, and Evidence Synthesis (HOPES)
The UConn Health Outcomes, Policy, and Evidence Synthesis (HOPES) group codifies collective strength in the areas of outcomes research: Systematic Review and Meta-Analysis, Economic Modeling, Clinical Trials, and Observational Research. HOPES provide the federal government and their key stakeholders (payors, clinicians, national medical and patient advocate organizations, and patients) with comparative effectiveness assessments that support evidence-based decisions.
Learn More about HOPES
Performance Improvement for Safe Medication Management (PRISM)
Improving the health of the people of the State of Connecticut, the Northeast, and beyond through safe and effective medication use that involves interdisciplinary educational programs, community-based research collaborations, health care transformation policy opportunities,and team-based care delivery.
Learn More about PRISM
New England Pharmacy Community Research Network
A collaboration between pharmacists, pharmacy researchers, pharmacies, prescribers, patients, payers, policy makers, and other stakeholders to advance and enhance pharmacy research and patient care —
improving patient outcomes.
Learn More about New England Pharmacy Community Research Network
Pharmacy Practice Faculty Publications
Department of Pharmacy Practice Faculty Publications
Independent Student Research Opportunities
UConn School of Pharmacy offers the opportunity to get involved in independent research should you wish to explore any area in more depth. Whether you are interested in pharmacy industry, a focus on government legislation, research on addiction or pharmaceuticals for cancer, our faculty will help to guide your study. Independent research students are paired with a faculty advisor that helps to guide an enriching and successful experience.
Independent Research in Pharmaceutical Sciences
Students interested in exploring independent research opportunities in Pharmaceutical Sciences can review faculty research above and contact pharmacy@uconn.edu with their area off interest
Independent Research in Pharmacy Practice
Students interested in pursuing pharmacy practice related research can review the collaborative centers above and contact pharmacy@uconn.edu with their area of interest.
Research Centers and Programs
Pharmaceutical Sciences faculty are involved in many different multifaceted research programs associated with UConn and industry around the region and nation. These centers of research excellence provide faculty with connections to complementary leaders in pharmacy industry.
Center for Pharmaceutical Processing Research (CPPR)
The Center for Pharmaceutical Process Research (CPPR) is a collaborative program that brings together select universities and industry colleagues for cooperative research projects between academia and industry. The mission of the Center for Pharmaceutical Process Research is to foster an interdisciplinary approach to pharmaceutical processing-related research, to catalyze interaction between industrial and academic scientists, and to make the application of a basic science approach to formulation and manufacture of drug products an integral part of graduate pharmaceutical education.
cppr.uconn.edu
Technology Incubation Program (TIP)
By coupling UConn's world-class research resources, facilities, and business support services to a network of experienced investors and entrepreneurs, we help launch startups ready to transform their respective markets.
Technology Incubation Program (TIP)
Research Facilities
Our research facilities offers the nuanced needs to conduct cross-disciplinary research and unprecedented growth in academies, research, and clinical care.
Harold G. Hewitt Pharmaceutical Sciences Research Laboratories
Research in medicinal chemistry, pharmaceutics, behavioral pharmacology, and pharmacology/toxicology is conducted in laboratories customized for the specialized requirements of each researcher. The laboratories contain multiple autoclaves, tissue culture facilities, state-of-the-art hooding and ventilation systems, and freeze-drying capabilities. Harold G. Hewitt Pharmaceutical Sciences Research Laboratories also houses a nuclear magnetic resonance facility and protein x-ray crystallography facility.
Location:
69 North Eagleville Road, Storrs, CT
Pharmacy building - north wing on the fourth, fifth, and sixth floors
UConn’s Innovation Partnership Building
In addition, UConn's Innovation Partnership Building at Tech Park on campus houses business partners from around the globe who team with our faculty to conduct innovative, cross-disciplinary research in fields ranging from manufacturing to biomedical engineering to cybersecurity.
Location:
159 Discovery Dr, Storrs, CT
Learn more at
techpark.uconn.edu
UConn Health and Jackson Laboratories
At nearby Farmington, our
UConn Health
campus, also home to
The Jackson Laboratory
, is an integrated academic medical center that is entering an era of unprecedented growth in all three areas of its mission: academics, research, and clinical care.
Location:
263 Farmington Avenue, Farmington, CT
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Harold G. Hewitt Pharmaceutical Sciences Research Laboratories
The Harold G. Hewitt Pharmaceutical Sciences Research Laboratories are located in the north wing of the building on the fourth, fifth, and sixth floors. Medicinal chemistry, pharmaceutics, behavioral pharmacology, and pharmacology/toxicology research is conducted in laboratories customized for the specialized requirements of each researcher. The laboratories contain multiple autoclaves, tissue culture facilities, state-of-the-art hooding and ventilation systems, and freeze-drying capabilities. We also have a nuclear magnetic resonance facility and a protein x-ray crystallography facility.
UConn’s Innovation Partnership Building
In addition, UConn's Innovation Partnership Building at Tech Park on campus houses business partners from around the globe who team with our faculty to conduct innovative, cross-disciplinary research in fields ranging from manufacturing to biomedical engineering to cybersecurity.
UConn Health and Jackson Laboratories
At nearby Farmington, our UConn Health campus, also home to Jackson Laboratories, is an integrated academic medical center that is entering an era of unprecedented growth in all three areas of its mission: academics, research, and clinical care.