INTRODUCTION Colorectal cancer (CRC) occurs through a multi-step process (polyp-adenoma-carcinoma) in which several mutations are associated with disease progression [ 1 , 2 ]. The most frequent mutations (40-70%) occur in the adenomatous polyposis coli (APC) gene, a component of…

Abstract Background Evidence-based medicine (EBM) has developed as the dominant paradigm of assessment of evidence that is used in clinical practice. Since its development, EBM has been applied to integrate the best available research into diagnosis and treatment with the purpose…

INTRODUCTION Commensal microbiota in the gut have profound effects on human health ( Backhed et al., 2005 ; Honda and Littman, 2012 ). Germ-free and antibiotic-treated mice are more susceptible for dextran sulfate sodium (DSS)-induced colonic inflammation ( Maslowski et al., 2009…

IODP Publications • Volume 397 expedition reports • Site U1587 Hodell, D.A., Abrantes, F., Alvarez Zarikian, C.A., and the Expedition 397 Scientists Proceedings of the International Ocean Discovery Program Volume 397 publications.iodp.org https://doi.org/10.14379/iodp.proc.397.10…

IODP Publications • Volume 397 expedition reports • Expedition 397 summary Hodell, D.A., Abrantes, F., Alvarez Zarikian, C.A., and the Expedition 397 Scientists Proceedings of the International Ocean Discovery Program Volume 397 publications.iodp.org https://doi.org/10.14379/iodp…

Summary paragraph Multiple sclerosis (MS) is a chronic autoimmune disease targeting the central nervous system (CNS). MS develops almost exclusively in individuals previously infected with Epstein–Barr virus (EBV) 1 , yet the mechanisms linking EBV infection to MS pathogenesis re…

Oncogene (2008) 27, 6044–6055 & 2008 Macmillan Publishers Limited All rights reserved 0950-9232/08 $32.00 www.nature.com/onc ORIGINAL ARTICLE Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses b-catenin-dependent transc…

…OA 출판 논문게재료(APC) 면제 및 할인 계약 출판사(알파벳順) ※ 도서관 승인 논문: 논문 투고 시 교신저자 정보에 서울대학교(기관명) @snu.ac.kr(이메일) 모두 표기 된 논문에 한해 승인 ※ APC 면제 혜택은 혜택 지원 시점에 서울대학교에 실제로 소속된 저자에게만 적용 되며, 허위 선택 시 불이익이 발생할 수 있습니다 「서울대학교 중앙도서관 오픈액세스 출판 지원 및 논문 관리지침」 OA 계약 출판사 (저널) 상세 내용 저널 목록 가이드 ACM Journals APC 면제, 출판 무…

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Article Free access | 10.1172/JCI9918 IL-10–producing T cells suppress immune responses in anergic tuberculosis patients 1 Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA 2 Division of Medical Oncology, and 3 Department of Medicine, Brigham …

IODP Publications • Volume 403 expedition reports • Expedition 403 methods Lucchi, R.G., St. John, K.E.K., Ronge, T.A., and the Expedition 403 Scientists Proceedings of the International Ocean Discovery Program Volume 403 publications.iodp.org https://doi.org/10.14379/iodp.proc.4…

EDP Sciences - Publication Charges Publication Charges Breadcrumbs fullpage Publication Charges Open Access charges for journals As a learned society publisher, EDP Sciences supports open access and the dissemination of science. It is our willingness to transition our entire port…

…ohort colorectal cancer: a new phenomenon Colorectal cancer (CRC) epidemiology is changing due to a birth cohort effect, first recognized by increasing incidence of early onset CRC (EOCRC, age <50 years) among individuals born 1960 and later (also previously described as among in…

Previous | Next doi:10.2204/iodp.proc.346.102.2015 Methods 1 R. Tada, R.W. Murray, C.A. Alvarez Zarikian, W.T. Anderson Jr., M.-A. Bassetti, B.J. Brace, S.C. Clemens, M.H. da Costa Gurgel, G.R. Dickens, A.G. Dunlea, S.J. Gallagher, L. Giosan, A.C.G. Henderson, A.E. Holbourn, K. I…

Abstract The success of in vivo gene therapy greatly depends on the ability to control the immune response toward the therapeutic transgene. Over the last decade several vector-based and pharmacological approaches have been explored to control the immune-mediated clearance of tra…