Signal Transduction and Targeted Therapy REVIEW ARTICLE www.nature.com/sigtrans OPEN Emerging insights into HAUSP (USP7) in physiology, cancer and other diseases Seemana Bhattacharya1, Dipankar Chakraborty1, Malini Basu2 and Mrinal K Ghosh1 Herpesvirus-associated ubiquitin-specifi…

Objective: To investigate the effect of statin use after radical prostatectomy (RP) on biochemical recurrence (BCR) in patients with prostate cancer who never received statins before RP. Patients and methods: We conducted a retrospective analysis of 1146 RP patients within the Sh…

Signal Transduction and Targeted Therapy REVIEW ARTICLE www.nature.com/sigtrans OPEN Emerging insights into HAUSP (USP7) in physiology, cancer and other diseases Seemana Bhattacharya1, Dipankar Chakraborty1, Malini Basu2 and Mrinal K Ghosh1 Herpesvirus-associated ubiquitin-specifi…

Outgassing Composition of the Murchison Meteorite: Implications for Volatile Depletion of Planetesimals and Interior-atmosphere Connections for Terrestrial Exoplanets - IOPscience The American Astronomical Society (AAS) , established in 1899 and based in Washington, DC, is the ma…

Research Article Autoimmunity Free access | 10.1172/JCI28546 Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis 1 Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, Ca…

Abstract Ponatinib, the only approved all known-BCR::ABL1 inhibitor, is a third-generation tyrosine-kinase inhibitor (TKI) designed to inhibit BCR::ABL1 with or without any single resistance mutation, including T315I, and induced robust and durable responses at 45 mg/day in patie…

Lens to Law | Wail Of A Tale Have you been affected by healthcare cuts? Take our survey and let us hear your story. DOCUMENTARY FILM PRODUCING WAVES FOR SOCIAL CHANGE Lens to Law Federal COVID-19 Reinfection Mitigation Program Evidence Infrastructure for the 119th Congress | Wail…

…যালয়গুলোর ঘনত্ব জুড়ে। এর মধ্যে সামার প্যালেস অন্তর্ভুক্ত। শিজিংশান জেলা (石景山区 Shíjǐngshānqū) কিছু পশ্চিমাঞ্চলীয় উপকণ্ঠ এবং পশ্চিম পাহাড়ের কিছু অংশ জুড়ে। ফেংতাই জেলা (丰台区 Fēngtáiqū) বেইজিংয়ের দক্ষিণ-পশ্চিম অংশ জুড়ে। এর মধ্যে বেইজিং পশ্চিম রেলওয়ে স্টেশন অন্তর্ভুক্ত। জানুন স…

JCI - B cell–based therapy produces antibodies that inhibit glioblastoma growth Go to JCI Insight About Editors Consulting Editors For authors Publication ethics Publication alerts by email Advertising Job board Contact The Journal of Clinical Investigation Current issue Past iss…

Log In Sign Up About Press Papers Terms Privacy Copyright We're Hiring! Help Center Claim details Research claim Biological contamination rates (BCR) ranged from 0 to 7 alien species per decade in selected ecosystems, indicating variable invasion risk in Europe. Amphipoda Crustac…

This document was last amended in November 2024 to reflect literature that was released since the original publication of this content in May 2013. This document will continue to be periodically updated to reflect the growing body of literature related to this topic. Keywords: Pr…

Background: The impact of race and socioeconomic status (SES) in prostate cancer (CaP) outcomes has been well-studied, but controversy remains. The associations of race/SES with intermediate CaP outcomes, including positive surgical margin (PSM) and biochemical recurrence (BCR), …

Abstract Ponatinib has potent activity against native and mutant BCR-ABL1, including BCR-ABL1 T315I The pivotal phase 2 Ponatinib Ph + ALL and CML Evaluation (PACE) trial evaluated efficacy and safety of ponatinib at a starting dose of 45 mg once daily in 449 patients with chroni…

1455 Diversity and variation of theropod dinosaur teeth from the uppermost Santonian Milk River Formation (Upper Cretaceous), Alberta: a quantitative method supporting identification of the oldest dinosaur tooth assemblage in Canada Derek W. Larson Abstract: The Santonian Deadho…

Background: Obesity is associated with an increased risk of biochemical recurrence (BCR) after radical prostatectomy (RP). It is unclear whether this is due to technical challenges related to operating on obese men or other biologic factors. Objective: To examine whether obesity …