I. INTRODUCTION The aim of this review is to describe recent advances in the molecular and behavioral biology of corticotropin releasing factor type 1 (CRF 1 ) and type 2 (CRF 2 ) receptors. We will review current knowledge regarding CRF receptor ligands, CRF receptor subtypes, s…
The National Institute for Health and Care Research (NIHR) is paid for by the Department of Health and Social Care (DHSC). It aims to deliver health and care research in the UK, to improve people’s health and wellbeing. One way the NIHR does this is by providing the facilities ne…
Introduction Since the isolation of corticotropin-releasing factor (CRF) in 1981 ( Vale et al ., 1981 ), several other mammalian CRF-like peptides with potential roles in energy homeostasis have been identified, including urocortins 1, 2 and 3 (Ucn 1, Ucn 2 and Ucn 3). Two mammal…
Introduction The remarkable plasticity of adipose tissue was thought to exist for excess energy storage or for use in times of famine. It is now clear that adipose is not a passive tissue, but rather a complex milieu of multiple cell types that respond to and influence many physi…
Abstract Increased corticotroping releasing factor (CRF) contributes to brain circuit abnormalities associated with stress related disorders including posttraumatic stress disorder. However, the causal relationship between CRF hypersignaling and circuit abnormalities associated w…
INTRODUCTION The Locus Coeruleus (LC) is a cluster of noradrenergic neurons in the midbrain that is the predominant provider of norepinephrine (NE) to the forebrain ( Berridge and Waterhouse 2003 , Valentino and Van Bockstaele 2008 , Benarroch 2009 ). The LC-NE system is critical…
Abstract Post-weaning social isolation of rodents is used to model developmental stressors linked to neuropsychiatric disorders including schizophrenia as well as anxiety and mood disorders. Isolation rearing produces alterations in emotional memory and hippocampal neuropathology…
Chancellor's Research Fellowship | Center for Undergraduate Research and Engaged Learning Chancellor's Research Fellowship The UC Riverside Chancellor's Research Fellowship (CRF) is a highly competitive award designed to support undergraduate students engaged in faculty-mentored …
…ntity Recognition for Information Retrieval in the Archaeology Domain ALEX BRANDSEN, SUZAN VERBERNE, KARSTEN LAMBERS, and MILCO WANSLEEBEN, Leiden University The amount of archaeological literature is growing rapidly. Until recently, these data were only accessible through metada…
Abstract The normal diurnal cortisol cycle has a peak in the morning, decreasing rapidly over the day, with low levels during the night, then rising rapidly again to the morning peak. A pattern of flatter daytime slopes has been associated with more rapid cancer progression in bo…
JOURNAL OF PSYCHIATRIC Journal of Psychiatric Research 40 (2006) 1–21 RESEARCH www.elsevier.com/locate/jpsychires Review Posttraumatic stress disorder: A state-of-the-science review Charles B. Nemeroff a,*, J. Douglas Bremner b, Edna B. Foa c, Helen S. Mayberg d, Carol S. North e,…
Yseop at SemEval-2020 Task 5: Cascaded BERT Language Model for Counterfactual Statement Analysis Hanna Abi Akl Dominique Mariko Estelle Labidurie Yseop Yseop Yseop [email protected] [email protected] [email protected] Abstract In this paper, we explore strategies to detect and ev…
Identifying Sources of Opinions with Conditional Random Fields and Extraction Patterns Yejin Choi and Claire Cardie Ellen Riloff and Siddharth Patwardhan Department of Computer Science School of Computing Cornell University University of Utah Ithaca, NY 14853 Salt Lake City, UT 8…
Labeling by Landscaping: Classifying Tokens in Context by Pruning and Decorating Trees ∗ Siddharth Patwardhan Branimir Boguraev Apoorv Agarwal IBM Watson Research Center IBM Watson Research Center Dept. of Computer Science 1101 Kitchawan Road 1101 Kitchawan Road Columbia Universi…
Information Processing and Management xxx (xxxx) xxx–xxx Contents lists available at ScienceDirect Information Processing and Management journal homepage: www.elsevier.com/locate/infoproman On constituent chunking for Turkish ⁎ Ozkan Aslana, , Serkan Gunalb, Bekir Taner Dincera a…