Abstract The basal levels of cytosolic calcium ([Ca2+]i) in rats and/or humans with chronic renal failure (CRF) are elevated in many cells including brain synaptosomes, pancreatic islets, polymorphonuclear leukocytes, platelets and B and T cells. This rise in [Ca2+]i has been att…
Abstract Earlier studies have demonstrated increased oxygen free radical (OFR) activity, diminished antioxidant capacity and reduced OFR-inactivating enzymes in chronic renal failure (CRF). Via inactivation of nitric oxide (NO), oxidation of arachidonic acid and a direct vasocons…
Abstract A systematic characterization of compulsivity in pathological forms of eating has been proposed in the context of three functional domains: (1) habitual overeating; (2) overeating to relieve a negative emotional state; and (3) overeating despite aversive consequences. In…
Abstract Chronic renal failure (CRF) is associated with increased Ca2+ content of liver and reduced hepatic lipase activity. This has been attributed to a rise in cytosolic Ca2+ ([Ca2+]i) of the hepatocytes, but data on this issue are lacking. We examined the [Ca2+]i and ATP cont…
Background: Cancer-related fatigue (CRF) is a debilitating side effect among patients with cancer. While exercise is recommended to manage CRF, clinical guidelines lack specificity on modality, intensity, and duration. This study aimed to determine the optimal doses of walking to…
Abstract Recent studies have revealed marked down-regulation of hepatic lipase (HL), lipoprotein lipase (LPL) and very low density lipoprotein-receptor (VLDL-R) expressions in animals with chronic renal failure (CRF). Acquired deficiency of these proteins, which together play an …
Abstract VLDL receptor (VLDL-R) is a novel member of the LDL receptor gene family with distinct tissue distribution and function. It binds and internalizes VLDL particles and is primarily expressed in skeletal muscle, heart, brain and adipose tissue, which use fatty acids for ene…
Papers by Sriram Yennurajalingam What are the best terms in Portuguese to explain the concepts of “fatigue” and “depression” in cancer patients? Palliative and Supportive Care , 2014 Objective: Although &…
During Earth Week, Governor Kathy Hochul today announced that since 2021, New York State has dedicated more than $240 million to support on-farm environmental protection projects and County Soil and Water Conservation District capacity. This includes record funding for the Climat…
Walking dose associated with lower cancer-related fatigue among patients with breast cancer Abstract Background: Cancer-related fatigue (CRF) is a debilitating side effect among patients with cancer. While exercise is recommended to manage CRF, clinical guidelines lack specificit…
Cultivating Change: The Inspiring Journey of Joel Copeland in Monthly Conservation Philanthropy - Coral Restoration Foundation Skip to content About Why Save Coral Reefs Coral reefs are a vital part of our planet’s life support system, providing food and coastal protection for mi…
Abstract Markers of hyperactive central corticotropin releasing factor (CRF) systems and CRF-related single nucleotide polymorphisms (SNPs) have been identified in patients with anxiety and depressive disorders. Designing more effective antagonists may now be guided by data showi…
Abstract Post-weaning social isolation of rodents is used to model developmental stressors linked to neuropsychiatric disorders including schizophrenia as well as anxiety and mood disorders. Isolation rearing produces alterations in emotional memory and hippocampal neuropathology…
Abstract The available data on the effect of chronic renal failure (CRF) on nitric oxide (NO) metabolism are limited and contradictory. We studied rats with CRF 6 wk after a five-sixths nephrectomy and compared the results with those in the sham-operated controls, felodipine-trea…
Background: Chronic renal failure (CRF) is associated with hypertriglyceridaemia and depressed plasma high-density lipoprotein (HDL)-cholesterol and apolipoprotein A-I (Apo A-I) concentrations. Uraemic hypertriglyceridaemia is due, in part, to lipoprotein lipase and hepatic lipas…