Clinical Research and Public Health Ophthalmology Open Access | 10.1172/JCI154218 In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope 1 International Center for Translational Eye Research and 2 Department of Physical Chemistry of B…
Introduction Regenerative, cutting-edge surgical and molecular medicine treatments, and personalized medicine approaches are viewed as new wave of therapies to treat incurable diseases and even aging. 1–4 Among those therapies are stem/cell and gene therapy approaches, 2 , 5–8 mo…
Reduction and oxidation of retinoids are key reactions of the retinoid cycle (visual cycle), which is critical for the production of the chromophore of rhodopsin, 11- cis -retinal ( 1 , 2 ). When light strikes the visual pigments (rhodopsin and cone opsins) in photoreceptors, it …
CDC's RPE Program The RPE program works to prevent sexual violence by providing funding to state and territorial health departments in all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands, and state, territorial, and tribal sexual assault coalitions. …
Introduction Aneurysmal type 1 neovascularization is a generic descriptor derived from terminology, which is established in the literature but has fallen out of use. We believe that aneurysmal type 1 neovascularization accurately describes the lesions which define the entity know…
IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY, VOL. 43, NO. 4, NOVEMBER 1994 909 A Comparative Study of Narrowband Microcellular Speech Transmission Schemes John E. B. Williams, Lajos Hanzo, Senior Member, IEEE, Raymond Steele, Senior Member, IEEE, and Joseph C. S. Cheung Abstract-Ex…
The role of retinol dehydrogenase 10 in the cone visual cycle - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( ) or https:// means you've safely connec…
The Case for Collective Reparations before the ICC Many have predicted that collective reparations would significantly shape the ICC reparations regime (Ferstman 2002) and the for the ICC to award such reparations is intuitively strong. Yet the degree to which collective reparati…
Abstract Lecithin:retinol acyltransferase (LRAT) catalyzes the acyl transfer from the sn -1 position of phosphatidylcholine (PC) to all- trans -retinol, creating fatty acid retinyl esters (palmitoyl, stearoyl, and some unsaturated derivatives). In the eye, these retinyl esters ar…
Abstract Purpose Subretinal injection (SRI) in mice is widely used in retinal research, yet the learning curve (LC) of this surgically challenging technique is unknown. Methods To evaluate the LC for SRI in a murine model, we analyzed training data from three clinically trained o…
Sensory neuropeptide CGRP and its co-receptor RAMP1 drive tumour cell growth in gastrointestinal cancers. BMJ Oncol. 2025; 4(1):e000842. Parathan P, Tran K, Neil L, Tan T, Carli ALE, Liao Y, Mouradov D, Da Gama Duarte J, Huber A, Pal B, Gibbs P, Sieber OM, Chiu IM, Kearney CJ, Sh…
Purpose: Mice with a targeted disruption of the gene encoding RPE65, a protein ordinarily highly expressed in the retinal pigment epithelium (RPE), accumulate abnormally high levels of all-trans retinyl ester in the RPE and exhibit very little 11-cis retinal in the retina. The pr…
ew Vol 3 | Issue 1 | Pages 33-37 Journal of Healthcare ISSN: 2689-8942 Case Report DOI: 10.36959/569/458 Spontaneous Retinal Pigment Epithelium Rips under Fovea with Preserved Good Visual Acuity Outcome Sunny Chi Lik Au* and Callie Ka Li Ko Check for Department of Ophthalmology, …
Abstract Purpose To evaluate the ability of retro mode illumination imaging for quantifying atrophy compared to confocal color fundus photography (c-CFP), green light fundus autofluorescence (G-FAF), blue light fundus autofluorescence (B-FAF) using the scanning laser ophthalmosco…
Abstract Retinoids carry out essential functions in vertebrate development and vision. Many of the retinoid processing enzymes remain to be identified at the molecular level. To expand the knowledge of retinoid biochemistry in vertebrates, we studied the enzymes involved in plant…