In the last several years, deep-sequencing has been fueling new and unexpected discoveries in the field of ncRNAs. These discoveries have been leading us away from the linear view of the “Central Dogma of Biology” and towards a framework in which ncRNAs are as important as protei…

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A comprehensive repertoire of tRNA-derived fragments in prostate cancer - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( ) or https:// means you've saf…

Prostate cancer (PCa) is the most common cancer among men in developed countries. Although its genetic background is thoroughly investigated, rather little is known about the role of small non-coding RNAs (sncRNA) in this disease. tRNA-derived fragments (tRFs) represent a new cla…

A standardised open science framework for sharing and re-analysing neural data acquired to continuous stimuli Giovanni M. Di Liberto1,*,**, Aaron Nidiffer2, Michael J. Crosse3,4, Nathaniel Zuk5, Stephanie Haro6,7, Giorgia Cantisani8,1, Martin M. Winchester1, Aoife Igoe1, Ross McC…

So far, we have used MINTmap to analyze 843 public short RNA-seq datasets from a variety of cellular contexts 2 , 11 . We are currently hosting the results of these analyses in MINTbase 1 , which was developed in the context of a parallel project. MINTbase is an unrestricted, int…

bioRxiv preprint doi: https://doi.org/10.1101/2022.10.11.511716; this version posted October 14, 2022. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It…

RESEARCH ARTICLE Cortical encoding of melodic expectations in human temporal cortex Giovanni M Di Liberto1*, Claire Pelofi2,3†, Roberta Bianco4†, Prachi Patel5,6, Ashesh D Mehta7,8, Jose L Herrero7,8, Alain de Cheveigné1,4, Shihab Shamma1,9*, Nima Mesgarani5,6* 1 Laboratoire des…

INTRODUCTION A major characteristic of the last decade is the explosion in the amount of genomic, transcriptomic, epigenomic, and other “–omic” data that can be generated for a given individual, healthy or patient. Not surprisingly, the ensuing data tsunami enabled invaluable int…

INTRODUCTION A major characteristic of the last decade is the explosion in the amount of genomic, transcriptomic, epigenomic, and other “–omic” data that can be generated for a given individual, healthy or patient. Not surprisingly, the ensuing data tsunami enabled invaluable int…

Identification of six types of genomic regions based on TRF binding data We selected five ENCODE cell lines that have the largest numbers of TRFs with binding sites assayed by ChIP-seq (Table S1 in Additional file 1 ). In total, 117 TRFs are included in the ENCODE datasets from t…

Abstract Huntington’s Disease (HD) is a neurodegenerative disorder caused by an autosomal-dominant mutation in the huntingtin gene, which manifests with a triad of motor, cognitive and psychiatric declines. Individuals with HD often present with disturbed sleep/wake cycles, but i…

Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A lock ( ) or…

Patients, samples, and sequencing limitations 526 samples were obtained from 472 patient donors. The patients span a range of ages and several races (Table 1 ). These samples form evenly sized subgroups from the standpoint of Gleason score at initial diagnosis (Table 1 ). It is i…

Revista Psicologia: Teoria e Prática, 20(3), 283-298. São Paulo, SP, set.-dez. 2018. ISSN 1516-3687 (impresso), ISSN 1980-6906 (on-line). http://dx.doi.org/10.5935/1980-6906/psicologia.v20n3p299-313. Sistema de avaliação: às cegas por pares (double blind review). Universidade Pre…