1998-1999 The Prosopography of the Neo-Assyrian Empire, volume 1 (= part 1: A and part 2: B-G). Helsinki: The Neo-Assyrian Text Corpus Project, 1998 and 1999. ISBN 9514581636 and ISBN 951458645X. THE PROSOPOGRAPHY OF THE NEO-ASSYRIAN EMPIRE VOLUME 1, PART I: A Using the Electroni…
Introduction Diminished growth hormone (GH) and insulin/insulin-like growth factor-1 (IGF-1) signaling extends lifespan in many laboratory models, including mutations to daf2 in worms 1 , Sch9 in yeast 2 , and Chico in drosophila 3 . Likewise, several dwarf models, including Ames…
Abstract Monoclonal antibodies (MAbs) to the Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP) were characterized for their ability to neutralize the infectivity of this organism in vitro and in vivo. One of the MAbs (MoPn-23) recognizes a nonline…
Abstract Background A large pool of preexisting alloreactive effector T cells can cause allogeneic graft rejection following transplantation. However, it is possible to induce transplant tolerance by altering the balance between effector and regulatory T (Treg) cells. Among the v…
The Journal of Immunology Heligmosomoides polygyrus Elicits a Dominant Nonprotective Antibody Response Directed against Restricted Glycan and Peptide Epitopes James P. Hewitson,*,1 Kara J. Filbey,*,1 John R. Grainger,*,2 Adam A. Dowle,† Mark Pearson,* Janice Murray,* Yvonne Harcu…
Frontiers | Pathogenic Role of Circulating Citrullinated Antigens and Anti-Cyclic Monoclonal Citrullinated Peptide Antibodies in Rheumatoid Arthritis ORIGINAL RESEARCH article Front. Immunol. , 30 June 2021 Sec. Autoimmune and Autoinflammatory Disorders Volume 12 - 2021 | https:/…
Significance Lipoprotein lipase (LPL) plays a central role in plasma lipid metabolism, hydrolyzing the triglycerides in lipoproteins and releasing fatty acid nutrients for vital tissues. LPL is synthesized by adipocytes and myocytes and secreted into the interstitial spaces, wher…
Abstract The neural cell adhesion molecule L1 has been shown to function as a homophilic ligand in a variety of dynamic neurological processes. Here we demonstrate that the sixth immunoglobulin-like domain of human L1 (L1-Ig6) can function as a heterophilic ligand for multiple me…
Abstract Background Cardiac troponin I (cTnI) is the current standard biomarker for diagnosing acute myocardial infarction and for risk-stratification of acute coronary syndromes in patients. However it remains unclear how the epitope specificity of antibodies in immunoassays inf…
Abstract Infection by field strains of Foot-and-mouth disease virus (FMDV) is initiated by binding to certain species of arginine-glycine-aspartic acid (RGD)-dependent integrin including αvβ3 and the epithelial integrin αvβ6. In this report we show that the integrin αvβ1, when ex…
INTRODUCTION During early embryonic development, certain groups of cells, like neural crest cells, can transiently express locomotory properties that allow them to migrate long distances from their sites of origin and populate other areas of the embryo where they undergo differen…
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Significance Immunosuppression by regulatory T cells (Tregs) is essential for the maintenance of self-tolerance, but it is detrimental in cancer because Tregs inhibit antitumor immunity. Development of therapeutic tools to block Tregs in patients with cancer requires a precise un…
Documentation Name Last modified Size Description Parent Directory AS03CPPM/ 2023-12-07 17:50 - Coastal Pioneer MAB - At-Sea Test 3 Profiler Mooring AS03CPSM/ 2023-12-07 17:31 - Coastal Pioneer MAB - At-Sea Test 3 Surface Mooring AS04CPSW/ 2023-10-30 20:56 - Coastal Pioneer MAB -…
Frontiers | Monoclonal antibodies against lipopolysaccharide protect against Pseudomonas aeruginosa challenge in mice ORIGINAL RESEARCH article Front. Cell. Infect. Microbiol. , 22 June 2023 Sec. Antibiotic Resistance and New Antimicrobial drugs Volume 13 - 2023 | Published in Fr…