Original Research 15 June 2023 DOI 10.3389/fendo.2023.1189207 TYPE PUBLISHED OPEN ACCESS EDITED BY Magdalene K Montgomery, The University of Melbourne, Australia REVIEWED BY Laura Dearden, University of Cambridge, United Kingdom Patricia Parnet, Institut National de recherche pou…

Background Diabetic nephropathy (DN) remains the commonest cause of end stage renal disease. Albuminuria, the cardinal clinical feature of DN, is induced by mechanisms undergoing reappraisal [ 1 ], but which primarily involve podocyte pathology, along with alterations in the glom…

cells Article Pancreatic β-Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Metabolic Stressors in Female Mice Ramkumar Mohan 1,† , Seokwon Jo 1,† , Elina Da Sol Chung 1 , Eunice Oribamise 1 , Amber Lockridge 1 , Juan E. Abrahante-Lloréns 2 , Hai-Bin Ruan 1 , …

Polycomb protein Ezh2 regulates pancreatic β-cell Ink4a/Arf expression and regeneration in diabetes mellitus - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A …

Targeting PKCα alleviates iron overload in diabetes and hemochromatosis through the inhibition of ferroportin - PMC Skip to main content Official websites use .gov A .gov website belongs to an official government organization in the United States. Secure .gov websites use HTTPS A…

Probiotics ameliorate pioglitazone-associated bone loss in diabetic rats Ahmad Gholami Shiraz University of Medical Sciences Mohammad Hossein Dabbaghmanesh Shiraz University of Medical Sciences Younes Ghasemi Shiraz University of Medical Sciences Pedram Talezadeh Shiraz Universit…

Abstract Macrophages are cellular mediators of vascular inflammation and are involved in the formation of atherosclerotic plaques. These immune cells secrete proteases such as matrix metalloproteinases and cathepsins that contribute to disease formation and progression. Here, we …

Introduction Transplantation of therapeutic cells has been examined as potential treatments for a variety of diseases, including, β-cells replacement therapies 1 , bone marrow transplantation 2 , and Parkinson’s disease 3 , 4 . Engineerability of cells and their responsiveness to…

Mohammed Najm Abdullah Al Salam - University of Technology/Iraq Skip to main content Log In Sign Up About Press Papers Terms Privacy Copyright We're Hiring! Help Center Mohammed Najm Abdullah Al Salam University of Technology/Iraq , Computer Engineering , Faculty Member Followers…

ARTICLE https://doi.org/10.1038/s41467-019-11338-y OPEN Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes Amar Singh 1,11, Sabarinathan Ramachandran 1,11, Melanie L. Graham 2,11, Saeed Daneshmandi 3,11, David Heller 1, Wilma Lucia …

Thermoplastic Forming and Related Studies of the Supercooled Liquid Region of Metallic Glasses - CaltechTHESIS CaltechTHESIS A Caltech Library Service About Browse Deposit an Item Instructions for Students Thermoplastic Forming and Related Studies of the Supercooled Liquid Region…

biomedicines Article Exploring the Therapeutic Potential of Berberine and Tocopherol in Managing Diabetic Neuropathy: A Comprehensive Approach towards Alleviating Chronic Neuropathic Pain Faisal K. Alkholifi 1, * , Alhussain H. Aodah 2 , Ahmed I. Foudah 3 and Aftab Alam 3 1 Depar…

2. Neuropathic Pain Figure 1 depicts the area in which the peripheral and central nervous system meet in relation to pain signal transmission, which takes place in the dorsal horn of the spinal cord, and the signal is then transmitted to the brain. As depicted in Figure 1 , the p…

Alzheimer's disease (AD) can be divided into sporadic AD (SAD) and familial AD (FAD). Most AD cases are sporadic and may result from multiple etiologic factors, including environmental, genetic and metabolic factors, whereas FAD is caused by mutations of presenilins or amyloid-β …

Background/aims: The streptozotocin (STZ)-induced diabetic rat is a widely used animal model of human diabetic nephropathy. In this model, diabetic nephropathy progresses without significant elevation in blood pressure. Therefore, studies have examined the effect of hypertension …