Steven Mittelman | UCLA Profiles

Lipidomic profiles associated with treatment related hepatotoxicity in children with acute lymphoblastic leukemia. Support Care Cancer. 2026 Feb 17; 34(3):209. Mason EJ, Schraw JM, Woodhouse JP, Gramatges MM, Williams KJ, Chen B, Harrell MB, Taylor OA, Scheurer ME, Lupo PJ, Rabin KR, Yi JS, Huynh V, Mittelman SD, Orgel E, Brown A. PMID: 41699110; PMCID: PMC12909625.

View in:
PubMed   Mentions:
   Fields:
   Translation:
Humans
Incidence and outcomes of treatment-associated hepatotoxicity during pediatric acute lymphoblastic leukemia induction therapy: a Reducing Ethnic Disparities in Acute Leukemia (REDIAL) Consortium report. Haematologica. 2026 Jan 22. Chavana AN, Mason EJ, Woodhouse JP, Taylor OA, Gramatges MM, Yi JS, Pruitt S, Bernhardt BM, Ludwig K, Klesse L, Heym K, Griffin T, Roberts M, Erana R, Bernini JC, Zhu H, Lupo PJ, Rabin KR, Scheurer ME, Mittelman SD, Huynh V, Orgel E, Brown AL. PMID: 41568528.

View in:
PubMed   Mentions:
   Fields:
Co-culture shock. Cell Death Discov. 2026 Jan 21; 12(1):36. Behan JW, Mittelman SD. PMID: 41565629; PMCID: PMC12824203.

View in:
PubMed Mentions:
UTX coordinates TCF1 and STAT3 to control progenitor CD8+ T cell fate in autoimmune diabetes. J Clin Invest. 2026 Feb 16; 136(4). Chen HC, Bang MF, Wang HH, Shpargel KB, Kohn LA, Sailer D, Zhang S, McCarthy EC, Seyedsadr M, Stevens S, Pham CL, Zhou Z, Yin X, Wilkinson NM, Peluso EM, Bustillos C, Ortega JG, Yang L, Buzzelli AA, Capati RC, Chia DJ, Mittelman SD, Reh CM, Whitmire JK, Lechner MG, Hugo W, Su MA. PMID: 41401033; PMCID: PMC12904725.

View in:
PubMed   Mentions:
   Fields:
   Translation:
Humans Animals Cells
An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy. Blood Adv. 2025 Nov 25; 9(22):5802-5810. Mason EJ, Crain AM, Scheurer ME, Lupo PJ, Rabin KR, Taylor OA, Roberts M, Woodhouse JP, Chavana A, Ludwig K, Klesse L, Heym K, Griffin T, Erana R, Bernini JC, Gramatges MM, Yi JS, Pruitt SL, Bernhardt MB, Zhu H, Mittelman SD, Huynh V, Orgel E, Schraw JM, Brown AL. PMID: 40829116; PMCID: PMC12663015.

View in:
PubMed   Mentions:
   Fields:
Adipose tissue releases nucleosides. Am J Physiol Cell Physiol. 2026 Jan 01; 330(1):C142-C154. Zhang J, Le T, Ruiz-Torres V, Cohen M, Paharkova V, Abt E, Alnajjar HS, Tan J, Rashid K, Jones AE, Ball AB, Divakaruni AS, Paszkiewicz RL, Bandaru P, Mack JJ, Ashby JW, Kim J, Li G, Radu CG, Mittelman SD. PMID: 41269663; PMCID: PMC12742186.

View in:
PubMed   Mentions:
   Fields:
   Translation:
Humans Animals Cells
Adipose tissue explant culture using PDMS flow chambers: an alternative to static explant culture. Adipocyte. 2025 Dec; 14(1):2578286. Cohen M, Bandaru P, Szylo K, Nguyen N, Nadeak B, Paszkiewicz R, Ashby JW, Mack JJ, Tanaka L, Tan J, Khademhosseini A, Mittelman SD. PMID: 41132053; PMCID: PMC12562731.

View in:
PubMed   Mentions:
   Fields:
   Translation:
Humans Cells
Adipocytes Impair Mitoxantrone Cytotoxicity Against Acute Lymphoblastic Leukemia. EJHaem. 2025 Oct; 6(5):e70140. Cohen M, Orgel E, Nevarez-Mejia J, Chen T, Neely M, Louie S, Mittelman SD. PMID: 40896243; PMCID: PMC12397950.

View in:
PubMed Mentions:
The effect of continuous glucose monitoring feedback on glycaemic variability in youth with obesity: A within-participant feasibility study. Pediatr Obes. 2025 Oct; 20(10):e70035. Chimatapu SN, Mittelman SD, Klomhaus A, Vu MH, Habib M, Wisk LE, Black DS, Vidmar AP. PMID: 40590379; PMCID: PMC12233186.

View in:
PubMed   Mentions:
   Fields:
   Translation:
Humans
Metabolic Implications of Childhood Cancer. Curr Pediatr Rep. 2025; 13. Tan J, Shabane B, Orgel E, Mittelman SD. PMID: 41676454; PMCID: PMC12890196.

View in:
PubMed
Mentions:
1
Correlation Between Technology and Improved Outcomes in Youth With Type 1 Diabetes Mellitus: Prospective Study Examining Outcomes for Patients With Depression and Those With Public Insurance. JMIR Diabetes. 2025 Jun 03; 10:e70380. Emerson ND, Ferber C, Jackson NJ, Li J, Tsay E, Styne D, Gottschalk M, Mittelman SD, Moscicki AB. PMID: 40460446; PMCID: PMC12151526.

View in:
PubMed Mentions:
Calaspargase pegol and pegaspargase cause similar hepatosteatosis in mice. Haematologica. 2025 Apr 01; 110(4):1019-1022. Ruiz-Torres V, Chia JJ, Cohen M, Tan J, Rushing T, Tinajero J, Orgel E, Mittelman SD. PMID: 39568437; PMCID: PMC11959228.

View in:
PubMed   Mentions:
   Fields:
Three Siblings With Familial Isolated Hypoparathyroidism: A Diagnostic Journey From CASR to Novel GCM2 Variant. JCEM Case Rep. 2024 Nov; 2(11):luae185. Thambundit A, Martinez-Agosto JA, Kianmahd Shamshoni J, Winer KK, Mittelman SD. PMID: 39439810; PMCID: PMC11495326.

View in:
PubMed
Mentions:
1
Impact of Telemedicine Versus In-Person Pediatric Outpatient Type 1 Diabetes Visits on Immediate Glycemic Control: Retrospective Chart Review. JMIR Diabetes. 2024 Oct 01; 9:e58579. Ferber C, Mittelman SD, Moin T, Wilhalme H, Hicks R. PMID: 39353188; PMCID: PMC11480684.

View in:
PubMed Mentions:
Adipocyte maturation impacts daunorubicin disposition and metabolism. Eur J Clin Invest. 2024 Dec; 54(12):e14307. Li Z, Ngu R, Naik AA, Trinh K, Paharkova V, Liao H, Liu Y, Zhuang C, Le D, Pei H, Asante I, Mittelman SD, Louie S. PMID: 39254480.

View in:
PubMed
   Mentions:
1
   Fields:
   Translation:
Humans Cells
Neonatal Graves Disease Masquerading as Hemochromatosis. JCEM Case Rep. 2024 Jul; 2(7):luae132. Maggiotto L, Mittelman SD, Fallah R. PMID: 39049864; PMCID: PMC11267223.

View in:
PubMed Mentions:
Fasting-Mimicking Diet Inhibits Autophagy and Synergizes with Chemotherapy to Promote T-Cell-Dependent Leukemia-Free Survival. Cancers (Basel). 2023 Dec 16; 15(24). Buono R, Tucci J, Cutri R, Guidi N, Mangul S, Raucci F, Pellegrini M, Mittelman SD, Longo VD. PMID: 38136414; PMCID: PMC10741737.

View in:
PubMed
Mentions:
9
Wearable Devices Beyond Activity Trackers in Youth With Obesity: Summary of Options. Child Obes. 2024 Apr; 20(3):208-218. Chimatapu SN, Mittelman SD, Habib M, Osuna-Garcia A, Vidmar AP. PMID: 37023409; PMCID: PMC10979694.

View in:
PubMed
   Mentions:
8
   Fields:
   Translation:
Humans
Erratum. Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome. Diabetes 2022;71:2256-2271. Diabetes. 2023 Feb 01; 72(2):309. Yao T, Yan H, Zhu X, Zhang Q, Kong X, Guo S, Feng Y, Wang H, Hua Y, Zhang J, Mittelman SD, Tontonoz P, Zhou Z, Liu T, Kong X. PMID: 36409587; PMCID: PMC9871192.

View in:
PubMed   Mentions:
   Fields:
An addiction-based digital weight loss intervention: A multi-centre randomized controlled trial. Pediatr Obes. 2023 03; 18(3):e12990. Vidmar AP, Salvy SJ, Wee CP, Pretlow R, Fox DS, Yee JK, Garell C, Glasner S, Mittelman SD. PMID: 36484235; PMCID: PMC9905275.

View in:
PubMed
   Mentions:
7
   Fields:
   Translation:
Humans
From soup to nuts: Obesity impairs chemotherapy during early and late phases of acute lymphoblastic leukemia treatment. Cancer. 2023 01 01; 129(1):15-17. Orgel E, Mittelman SD. PMID: 36369919.

View in:
PubMed   Mentions:
   Fields:
   Translation:
Humans
Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome. Diabetes. 2022 11 01; 71(11):2256-2271. Yao T, Yan H, Zhu X, Zhang Q, Kong X, Guo S, Feng Y, Wang H, Hua Y, Zhang J, Mittelman SD, Tontonoz P, Zhou Z, Liu T, Kong X. PMID: 35713959; PMCID: PMC9630087.

View in:
PubMed
   Mentions:
10
   Fields:
   Translation:
Humans Animals
Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity. J Clin Invest. 2022 08 15; 132(16). Abt ER, Rashid K, Le TM, Li S, Lee HR, Lok V, Li L, Creech AL, Labora AN, Mandl HK, Lam AK, Cho A, Rezek V, Wu N, Abril-Rodriguez G, Rosser EW, Mittelman SD, Hugo W, Mehrling T, Bantia S, Ribas A, Donahue TR, Crooks GM, Wu TT, Radu CG. PMID: 35653193; PMCID: PMC9374381.

View in:
PubMed
   Mentions:
19
   Fields:
   Translation:
Humans Animals Cells
Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer Survivors (The AIM Trial): Rationale, Design, and Methods. Front Oncol. 2022; 12:896995. Kang DW, Wilson RL, Gonzalo-Encabo P, Norris MK, Hans M, Tahbaz M, Dawson J, Nguyen D, Normann AJ, Yunker AG, Sami N, Uno H, Ligibel JA, Mittelman SD, Dieli-Conwright CM. PMID: 35795051; PMCID: PMC9251632.

View in:
PubMed
Mentions:
1
Increased prevalence of CRLF2 rearrangements in obesity-associated acute lymphoblastic leukemia. Blood. 2021 07 15; 138(2):199-202. Mittelman SD, Kim J, Raca G, Li G, Oberley MJ, Orgel E. PMID: 33876219; PMCID: PMC8288656.

View in:
PubMed
   Mentions:
10
   Fields:
   Translation:
Humans
Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells. Front Oncol. 2021; 11:665763. Tucci J, Chen T, Margulis K, Orgel E, Paszkiewicz RL, Cohen MD, Oberley MJ, Wahhab R, Jones AE, Divakaruni AS, Hsu CC, Noll SE, Sheng X, Zare RN, Mittelman SD. PMID: 33968771; PMCID: PMC8100891.

View in:
PubMed
Mentions:
34
Caloric and nutrient restriction to augment chemotherapy efficacy for acute lymphoblastic leukemia: the IDEAL trial. Blood Adv. 2021 04 13; 5(7):1853-1861. Orgel E, Framson C, Buxton R, Kim J, Li G, Tucci J, Freyer DR, Sun W, Oberley MJ, Dieli-Conwright C, Mittelman SD. PMID: 33792627; PMCID: PMC8045487.

View in:
PubMed
   Mentions:
29
   Fields:
   Translation:
Humans CTClinical Trials
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth. Cell Metab. 2021 05 04; 33(5):1013-1026.e6. Krall AS, Mullen PJ, Surjono F, Momcilovic M, Schmid EW, Halbrook CJ, Thambundit A, Mittelman SD, Lyssiotis CA, Shackelford DB, Knott SRV, Christofk HR. PMID: 33609439; PMCID: PMC8102379.

View in:
PubMed
   Mentions:
144
   Fields:
   Translation:
Humans Animals Cells
Effect of Body Fat on Population Pharmacokinetics of High-Dose Methotrexate in Pediatric Patients With Acute Lymphoblastic Leukemia. J Clin Pharmacol. 2021 06; 61(6):755-762. Orgel E, Nabais T, Douglas C, Mittelman SD, Neely M. PMID: 33314168.

View in:
PubMed
   Mentions:
9
   Fields:
   Translation:
Humans
Flattening the Learning Curve: A Case-Based Video Orientation for a Subspeciality Residency Rotation. Acad Pediatr. 2021 Jan-Feb; 21(1):5-10. Shenoy RV, Mittelman SD, Relan A, Reh C, Yazdani S. PMID: 32858264.

View in:
PubMed
   Mentions:
2
   Fields:
   Translation:
Humans
Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020 07 09; 136(2):210-223. Gang EJ, Kim HN, Hsieh YT, Ruan Y, Ogana HA, Lee S, Pham J, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, Parekh C, Abdel-Azim H, Bhojwani D, Wayne AS, De Arcangelis A, Georges-Labouesse E, Wayner E, Bonig H, Minasyan A, Ten Hoeve J, Graeber TG, Müschen M, Heisterkamp N, Kim YM. PMID: 32219444; PMCID: PMC7357190.

View in:
PubMed
   Mentions:
34
   Fields:
   Translation:
Humans Animals
The Role of Diet in Cancer Prevention and Chemotherapy Efficacy. Annu Rev Nutr. 2020 09 23; 40:273-297. Mittelman SD. PMID: 32543948; PMCID: PMC8546934.

View in:
PubMed
   Mentions:
46
   Fields:
   Translation:
Humans
Levocarnitine does not impair chemotherapy cytotoxicity against acute lymphoblastic leukemia. Leuk Lymphoma. 2020 02; 61(2):420-428. Sea JL, Orgel E, Chen T, Paszkiewicz RL, Krall AS, Oberley MJ, Stiles L, Mittelman SD. PMID: 31526067; PMCID: PMC7305023.

View in:
PubMed
   Mentions:
3
   Fields:
   Translation:
Humans Animals
Mechanisms by Which Obesity Impacts Survival from Acute Lymphoblastic Leukemia. J Natl Cancer Inst Monogr. 2019 09 01; 2019(54):152-156. Orgel E, Sea JL, Mittelman SD. PMID: 31532535; PMCID: PMC6750167.

View in:
PubMed
   Mentions:
26
   Fields:
   Translation:
Humans PHPublic Health
Myosteatosis in adolescents and young adults treated for acute lymphoblastic leukemia. Leuk Lymphoma. 2019 12; 60(13):3146-3153. Mueske NM, Mittelman SD, Wren TAL, Gilsanz V, Orgel E. PMID: 31264493; PMCID: PMC6923569.

View in:
PubMed
   Mentions:
7
   Fields:
   Translation:
Humans CTClinical Trials
Central diabetes insipidus associated with refeeding in anorexia nervosa: A case report. Int J Eat Disord. 2019 06; 52(6):752-756. Rosen EL, Thambundit A, Mehler PS, Mittelman SD. PMID: 31038775.

View in:
PubMed
   Mentions:
6
   Fields:
   Translation:
Humans
Proposed endocrine funding priorities for the NICHD strategic plan: expert opinion from the Pediatric Endocrine Society. Pediatr Res. 2019 08; 86(2):141-143. Singer K, Katz ML, Mittelman SD, PES Research Affairs Committee. PMID: 30995675; PMCID: PMC6703171.

View in:
PubMed
   Mentions:
1
   Fields:
   Translation:
Humans
Iodine Nutrition in Weaning Infants in the United States. Thyroid. 2019 04; 29(4):573-576. Fallah R, Du L, Braverman LE, He X, Segura-Harrison M, Yeh MW, Pearce EN, Chiu HK, Mittelman SD, Leung AM. PMID: 30827204; PMCID: PMC6457884.

View in:
PubMed
   Mentions:
5
   Fields:
   Translation:
Humans PHPublic Health
Energy Management for Personalized Weight Reduction (EMPOWER) Program: Three-Year Outcome Data. Adv Clin Endocrinol Metab. 2019; 2(1):47-54. Vidmar AP, Fink C, Torres B, Manzanarez B, Mittelman SD, Wee CP, Borzutzky C. PMID: 32699839; PMCID: PMC7375743.

View in:
PubMed Mentions:
An addiction-based mobile health weight loss intervention: protocol of a randomized controlled trial. Contemp Clin Trials. 2019 03; 78:11-19. Vidmar AP, Salvy SJ, Pretlow R, Mittelman SD, Wee CP, Fink C, Steven Fox D, Raymond JK. PMID: 30654026; PMCID: PMC8078064.

View in:
PubMed
   Mentions:
13
   Fields:
   Translation:
Humans CTClinical Trials
Abnormalities in autonomic function in obese boys at-risk for insulin resistance and obstructive sleep apnea. Pediatr Res. 2019 05; 85(6):790-798. Oliveira FMS, Tran WH, Lesser DJ, Bhatia R, Keens TG, Mittelman SD, Davidson Ward SL, Khoo MCK. PMID: 30420708; PMCID: PMC6494692.

View in:
PubMed
   Mentions:
1
   Fields:
   Translation:
Humans
Switch to low-fat diet improves outcome of acute lymphoblastic leukemia in obese mice. Cancer Metab. 2018; 6:15. Tucci J, Alhushki W, Chen T, Sheng X, Kim YM, Mittelman SD. PMID: 30410754; PMCID: PMC6211598.

View in:
PubMed
Mentions:
13
An addiction model-based mobile health weight loss intervention in adolescents with obesity. Pediatr Obes. 2019 02; 14(2):e12464. Vidmar AP, Pretlow R, Borzutzky C, Wee CP, Fox DS, Fink C, Mittelman SD. PMID: 30117309; PMCID: PMC6338524.

View in:
PubMed
   Mentions:
34
   Fields:
   Translation:
Humans CTClinical Trials
Adipocyte metabolism of the chemotherapy daunorubicin. Oncoscience. 2018 May; 5(5-6):146-147. Mittelman SD, Orgel E. PMID: 30035170; PMCID: PMC6049316.

View in:
PubMed
Mentions:
4
Obesity and risk for venous thromboembolism from contemporary therapy for pediatric acute lymphoblastic leukemia. Thromb Res. 2018 05; 165:44-50. Prasca S, Carmona R, Ji L, Ko RH, Bhojwani D, Rawlins YA, Mittelman SD, Young G, Orgel E. PMID: 29567586; PMCID: PMC7522001.

View in:
PubMed
   Mentions:
15
   Fields:
   Translation:
Humans
Adipose tissue inflammation in breast cancer survivors: effects of a 16-week combined aerobic and resistance exercise training intervention. Breast Cancer Res Treat. 2018 Feb; 168(1):147-157. Dieli-Conwright CM, Parmentier JH, Sami N, Lee K, Spicer D, Mack WJ, Sattler F, Mittelman SD. PMID: 29168064; PMCID: PMC6233989.

View in:
PubMed
   Mentions:
64
   Fields:
   Translation:
Humans Cells
Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin. Mol Cancer Res. 2017 12; 15(12):1704-1713. Sheng X, Parmentier JH, Tucci J, Pei H, Cortez-Toledo O, Dieli-Conwright CM, Oberley MJ, Neely M, Orgel E, Louie SG, Mittelman SD. PMID: 29117945; PMCID: PMC5726435.

View in:
PubMed
   Mentions:
91
   Fields:
   Translation:
Humans Cells
A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro. Sci Rep. 2017 11 03; 7(1):14479. Maggi M, Mittelman SD, Parmentier JH, Colombo G, Meli M, Whitmire JM, Merrell DS, Whitelegge J, Scotti C. PMID: 29101342; PMCID: PMC5670125.

View in:
PubMed
   Mentions:
27
   Fields:
   Translation:
Humans Cells
A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia. Leuk Lymphoma. 2017 Oct; 58(10):2370-2378. Orgel E, Mueske NM, Sposto R, Gilsanz V, Wren TAL, Freyer DR, Butturini AM, Mittelman SD. PMID: 28278717; PMCID: PMC5489365.

View in:
PubMed
   Mentions:
10
   Fields:
   Translation:
Humans
Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response. Oncotarget. 2016 Nov 08; 7(45):73147-73159. Sheng X, Tucci J, Parmentier JH, Ji L, Behan JW, Heisterkamp N, Mittelman SD. PMID: 27705905; PMCID: PMC5341969.

View in:
PubMed
   Mentions:
41
   Fields:
   Translation:
Humans Animals Cells
Effects of exenatide on weight and appetite in overweight adolescents and young adults with Prader-Willi syndrome. Pediatr Obes. 2017 06; 12(3):221-228. Salehi P, Hsu I, Azen CG, Mittelman SD, Geffner ME, Jeandron D. PMID: 27071367; PMCID: PMC5288290.

View in:
PubMed
   Mentions:
37
   Fields:
   Translation:
Humans CTClinical Trials
Early injury to cortical and cancellous bone from induction chemotherapy for adolescents and young adults treated for acute lymphoblastic leukemia. Bone. 2016 Apr; 85:131-7. Orgel E, Mueske NM, Wren TA, Gilsanz V, Butturini AM, Freyer DR, Mittelman SD. PMID: 26851412; PMCID: PMC4795805.

View in:
PubMed
   Mentions:
13
   Fields:
   Translation:
Humans
Limitations of body mass index to assess body composition due to sarcopenic obesity during leukemia therapy. Leuk Lymphoma. 2018 01; 59(1):138-145. Orgel E, Mueske NM, Sposto R, Gilsanz V, Freyer DR, Mittelman SD. PMID: 26818609; PMCID: PMC5362342.

View in:
PubMed
   Mentions:
43
   Fields:
   Translation:
Humans
Fasting serum blood measures of bone and lipid metabolism in children with myelomeningocele for early detection of cardiovascular and bone fragility risk factors. J Spinal Cord Med. 2017 03; 40(2):193-200. Van Speybroeck A, Mueske NM, Mittelman SD, Kremer RK, Ryan DD, Wren TA. PMID: 26666357; PMCID: PMC5430477.

View in:
PubMed
   Mentions:
3
   Fields:
   Translation:
Humans
Increased Abdominal Adiposity in Adolescents and Young Adults With Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency. J Clin Endocrinol Metab. 2015 Aug; 100(8):E1153-9. Kim MS, Ryabets-Lienhard A, Dao-Tran A, Mittelman SD, Gilsanz V, Schrager SM, Geffner ME. PMID: 26062016; PMCID: PMC4524992.

View in:
PubMed
   Mentions:
35
   Fields:
   Translation:
Humans
Institutional adherence to cardiovascular risk factor screening guidelines for young survivors of acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2015 May; 37(4):e253-7. Lin MH, Wood JR, Mittelman SD, Freyer DR. PMID: 25757021.

View in:
PubMed
   Mentions:
3
   Fields:
   Translation:
Humans
Glutaminase activity determines cytotoxicity of L-asparaginases on most leukemia cell lines. Leuk Res. 2015 Jul; 39(7):757-62. Parmentier JH, Maggi M, Tarasco E, Scotti C, Avramis VI, Mittelman SD. PMID: 25941002; PMCID: PMC4458142.

View in:
PubMed
   Mentions:
56
   Fields:
   Translation:
Humans Cells
View in:
PubMed
   Mentions:
34
   Fields:
   Translation:
Humans PHPublic Health
Salsalate treatment improves glycemia without altering adipose tissue in nondiabetic obese hispanics. Obesity (Silver Spring). 2015 Mar; 23(3):543-51. Alderete TL, Sattler FR, Richey JM, Allayee H, Mittelman SD, Sheng X, Tucci J, Gyllenhammer LE, Grant EG, Goran MI. PMID: 25644856; PMCID: PMC4340767.

View in:
PubMed
   Mentions:
4
   Fields:
   Translation:
Humans PHPublic Health
A significant proportion of thalassemia major patients have adrenal insufficiency detectable on provocative testing. J Pediatr Hematol Oncol. 2015 Jan; 37(1):54-9. Huang KE, Mittelman SD, Coates TD, Geffner ME, Wood JC. PMID: 24942024; PMCID: PMC4393555.

View in:
PubMed
   Mentions:
14
   Fields:
   Translation:
Humans
Effects of vitamin D repletion on glycemic control and inflammatory cytokines in adolescents with type 1 diabetes. Pediatr Diabetes. 2016 Feb; 17(1):36-43. Shih EM, Mittelman S, Pitukcheewanont P, Azen CG, Monzavi R. PMID: 25524404.

View in:
PubMed
   Mentions:
17
   Fields:
   Translation:
Humans
Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia. Blood. 2014 Dec 18; 124(26):3932-8. Orgel E, Tucci J, Alhushki W, Malvar J, Sposto R, Fu CH, Freyer DR, Abdel-Azim H, Mittelman SD. PMID: 25349177.

View in:
PubMed
   Mentions:
60
   Fields:
   Translation:
Humans
The role of adipose tissue and obesity in causing treatment resistance of acute lymphoblastic leukemia. Front Pediatr. 2014; 2:53. Sheng X, Mittelman SD. PMID: 24926474; PMCID: PMC4046266.

View in:
PubMed
Mentions:
28
A novel biopsy method to increase yield of subcutaneous abdominal adipose tissue. Int J Obes (Lond). 2015 Jan; 39(1):183-6. Alderete TL, Sattler FR, Sheng X, Tucci J, Mittelman SD, Grant EG, Goran MI. PMID: 24849392; PMCID: PMC5764758.

View in:
PubMed
   Mentions:
8
   Fields:
   Translation:
Humans
Activation of adipose tissue macrophages in obese mice does not require lymphocytes. Obesity (Silver Spring). 2013 Jul; 21(7):1380-8. Behan JW, Ehsanipour EA, Sheng X, Pramanik R, Wang X, Hsieh YT, Kim YM, Mittelman SD. PMID: 23754826; PMCID: PMC3742678.

View in:
PubMed
   Mentions:
16
   Fields:
   Translation:
Animals Cells
Adipocyte differentiation is affected by media height above the cell layer. Int J Obes (Lond). 2014 Feb; 38(2):315-20. Sheng X, Tucci J, Malvar J, Mittelman SD. PMID: 23743593; PMCID: PMC4145870.

View in:
PubMed
   Mentions:
13
   Fields:
   Translation:
Humans Animals Cells
Adipocytes cause leukemia cell resistance to L-asparaginase via release of glutamine. Cancer Res. 2013 May 15; 73(10):2998-3006. Ehsanipour EA, Sheng X, Behan JW, Wang X, Butturini A, Avramis VI, Mittelman SD. PMID: 23585457; PMCID: PMC3684066.

View in:
PubMed
   Mentions:
107
   Fields:
   Translation:
Humans Animals Cells
The links between insulin resistance, diabetes, and cancer. Curr Diab Rep. 2013 Apr; 13(2):213-22. Orgel E, Mittelman SD. PMID: 23271574; PMCID: PMC3595327.

View in:
PubMed
   Mentions:
87
   Fields:
   Translation:
Humans Animals
Adipose tissue attracts and protects acute lymphoblastic leukemia cells from chemotherapy. Leuk Res. 2013 May; 37(5):503-9. Pramanik R, Sheng X, Ichihara B, Heisterkamp N, Mittelman SD. PMID: 23332453; PMCID: PMC3622767.

View in:
PubMed
   Mentions:
58
   Fields:
   Translation:
Humans Animals Cells
Sleep fragmentation and intermittent hypoxemia are associated with decreased insulin sensitivity in obese adolescent Latino males. Pediatr Res. 2012 Sep; 72(3):293-8. Lesser DJ, Bhatia R, Tran WH, Oliveira F, Ortega R, Keens TG, Mittelman SD, Khoo MC, Davidson Ward SL. PMID: 22669298; PMCID: PMC3427473.

View in:
PubMed
   Mentions:
28
   Fields:
   Translation:
Humans
Vitamin D protects acute lymphoblastic leukemia cells from dexamethasone. Leuk Res. 2012 May; 36(5):591-3. Antony R, Sheng X, Ehsanipour EA, Ng E, Pramanik R, Klemm L, Ichihara B, Mittelman SD. PMID: 22341429; PMCID: PMC3312954.

View in:
PubMed
   Mentions:
7
   Fields:
   Translation:
Humans Cells
Pituitary iron and volume predict hypogonadism in transfusional iron overload. Am J Hematol. 2012 Feb; 87(2):167-71. Noetzli LJ, Panigrahy A, Mittelman SD, Hyderi A, Dongelyan A, Coates TD, Wood JC. PMID: 22213195.

View in:
PubMed
   Mentions:
51
   Fields:
   Translation:
Humans
Pancreatic iron and glucose dysregulation in thalassemia major. Am J Hematol. 2012 Feb; 87(2):155-60. Noetzli LJ, Mittelman SD, Watanabe RM, Coates TD, Wood JC. PMID: 22120775.

View in:
PubMed
   Mentions:
63
   Fields:
   Translation:
Humans Cells
A longitudinal assessment of lipids in youth with type 1 diabetes. Pediatr Diabetes. 2011 Jun; 12(4 Pt 2):365-71. Reh CM, Mittelman SD, Wee CP, Shah AC, Kaufman FR, Wood JR. PMID: 21392191.

View in:
PubMed
   Mentions:
16
   Fields:
   Translation:
Humans
Effect of gender on intra-abdominal fat in teenagers and young adults. Pediatr Radiol. 2011 Apr; 41(4):469-75. Chung SA, Dorey F, Mittelman S, Gilsanz V. PMID: 21038077.

View in:
PubMed
   Mentions:
3
   Fields:
   Translation:
Humans
Diet-induced obesity accelerates acute lymphoblastic leukemia progression in two murine models. Cancer Prev Res (Phila). 2010 Oct; 3(10):1259-64. Yun JP, Behan JW, Heisterkamp N, Butturini A, Klemm L, Ji L, Groffen J, Müschen M, Mittelman SD. PMID: 20823291; PMCID: PMC2955776.

View in:
PubMed
   Mentions:
25
   Fields:
   Translation:
Humans Animals
Predicting pituitary iron and endocrine dysfunction. Ann N Y Acad Sci. 2010 Aug; 1202:123-8. Wood JC, Noetzl L, Hyderi A, Joukar M, Coates T, Mittelman S. PMID: 20712782.

View in:
PubMed
   Mentions:
16
   Fields:
   Translation:
Humans
Obese adolescents show impaired meal responses of the appetite-regulating hormones ghrelin and PYY. Obesity (Silver Spring). 2010 May; 18(5):918-25. Mittelman SD, Klier K, Braun S, Azen C, Geffner ME, Buchanan TA. PMID: 20094039; PMCID: PMC2940837.

View in:
PubMed
   Mentions:
28
   Fields:
   Translation:
Humans
Diet-induced obesity alters vincristine pharmacokinetics in blood and tissues of mice. Pharmacol Res. 2010 May; 61(5):385-90. Behan JW, Avramis VI, Yun JP, Louie SG, Mittelman SD. PMID: 20083201; PMCID: PMC2848885.

View in:
PubMed
   Mentions:
37
   Fields:
   Translation:
Animals
Autonomic and metabolic effects of OSA in childhood obesity. Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:6134-7. Oliveira FM, Tran WH, Lesser D, Bhatia R, Ortega R, Mittelman SD, Keens TG, Davidson Ward SL, Khoo MC. PMID: 21097142.

View in:
PubMed
   Mentions:
4
   Fields:
   Translation:
Humans
Adiposity predicts carotid intima-media thickness in healthy children and adolescents. J Pediatr. 2010 Apr; 156(4):592-7.e2. Mittelman SD, Gilsanz P, Mo AO, Wood J, Dorey F, Gilsanz V. PMID: 20004913.

View in:
PubMed
   Mentions:
15
   Fields:
   Translation:
Humans
Adipocytes impair leukemia treatment in mice. Cancer Res. 2009 Oct 01; 69(19):7867-74. Behan JW, Yun JP, Proektor MP, Ehsanipour EA, Arutyunyan A, Moses AS, Avramis VI, Louie SG, Butturini A, Heisterkamp N, Mittelman SD. PMID: 19773440; PMCID: PMC2756308.

View in:
PubMed
   Mentions:
114
   Fields:
   Translation:
Animals Cells
Reciprocal relations of subcutaneous and visceral fat to bone structure and strength. J Clin Endocrinol Metab. 2009 Sep; 94(9):3387-93. Gilsanz V, Chalfant J, Mo AO, Lee DC, Dorey FJ, Mittelman SD. PMID: 19531595; PMCID: PMC2741723.

View in:
PubMed
   Mentions:
176
   Fields:
   Translation:
Humans
Differential effect of marrow adiposity and visceral and subcutaneous fat on cardiovascular risk in young, healthy adults. Int J Obes (Lond). 2008 Dec; 32(12):1854-60. Di Iorgi N, Mittelman SD, Gilsanz V. PMID: 18838978; PMCID: PMC2605198.

View in:
PubMed
   Mentions:
21
   Fields:
   Translation:
Humans
Reciprocal relation between marrow adiposity and the amount of bone in the axial and appendicular skeleton of young adults. J Clin Endocrinol Metab. 2008 Jun; 93(6):2281-6. Di Iorgi N, Rosol M, Mittelman SD, Gilsanz V. PMID: 18381577; PMCID: PMC2435643.

View in:
PubMed
   Mentions:
90
   Fields:
   Translation:
Humans Cells
Relationship of highly sensitive C-reactive protein and lipid levels in adolescents with type 1 diabetes mellitus. Pediatr Diabetes. 2008 Apr; 9(2):122-6. Karantza MV, Mittelman SD, Dorey F, Samie S, Kaiserman K, Halvorson M, Kaufman FR. PMID: 18036131.

View in:
PubMed
   Mentions:
5
   Fields:
   Translation:
Humans
Fat mass is not beneficial to bone in adolescents and young adults. J Clin Endocrinol Metab. 2007 Jan; 92(1):143-7. Janicka A, Wren TA, Sanchez MM, Dorey F, Kim PS, Mittelman SD, Gilsanz V. PMID: 17047019.

View in:
PubMed
   Mentions:
114
   Fields:
   Translation:
Humans
A hypocalcemic child with a novel activating mutation of the calcium-sensing receptor gene: successful treatment with recombinant human parathyroid hormone. J Clin Endocrinol Metab. 2006 Jul; 91(7):2474-9. Mittelman SD, Hendy GN, Fefferman RA, Canaff L, Mosesova I, Cole DE, Burkett L, Geffner ME. PMID: 16608894.

View in:
PubMed
   Mentions:
9
   Fields:
   Translation:
Humans Cells
Obesity and fat quantification in lean tissues using three-point Dixon MR imaging. Pediatr Radiol. 2005 Jun; 35(6):601-7. Kovanlikaya A, Mittelman SD, Ward A, Geffner ME, Dorey F, Gilsanz V. PMID: 15785930.

View in:
PubMed
   Mentions:
47
   Fields:
   Translation:
Humans
Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding. J Clin Endocrinol Metab. 2002 Nov; 87(11):5191-8. van Citters GW, Kabir M, Kim SP, Mittelman SD, Dea MK, Brubaker PL, Bergman RN. PMID: 12414891.

View in:
PubMed
   Mentions:
10
   Fields:
   Translation:
Animals
Extreme insulin resistance of the central adipose depot in vivo. Diabetes. 2002 Mar; 51(3):755-61. Mittelman SD, Van Citters GW, Kirkman EL, Bergman RN. PMID: 11872676.

View in:
PubMed
   Mentions:
36
   Fields:
   Translation:
Animals Cells
Lack of hepatic "interregulation" during inhibition of glycogenolysis in a canine model. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E375-83. Fosgerau K, Mittelman SD, Sunehag A, Dea MK, Lundgren K, Bergman RN. PMID: 11440915.

View in:
PubMed
   Mentions:
3
   Fields:
   Translation:
Animals Cells
Central role of the adipocyte in the metabolic syndrome. J Investig Med. 2001 Jan; 49(1):119-26. Bergman RN, Van Citters GW, Mittelman SD, Dea MK, Hamilton-Wessler M, Kim SP, Ellmerer M. PMID: 11217141.

View in:
PubMed
   Mentions:
50
   Fields:
   Translation:
Humans Animals Cells
Paradoxical effect of troglitazone in normal animals: enhancement of adipocyte but reduction of liver insulin sensitivity. Diabetes. 2000 Dec; 49(12):2087-93. Dea MK, Van Citters GW, Ader M, Mittelman SD, Sunehag AL, Bergman RN. PMID: 11118011.

View in:
PubMed
   Mentions:
1
   Fields:
   Translation:
Animals Cells
Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes. 2000 Dec; 49(12):2116-25. Mittelman SD, Van Citters GW, Kim SP, Davis DA, Dea MK, Hamilton-Wessler M, Bergman RN. PMID: 11118015.

View in:
PubMed
   Mentions:
67
   Fields:
   Translation:
Animals
Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin. Am J Physiol Endocrinol Metab. 2000 Sep; 279(3):E630-7. Mittelman SD, Bergman RN. PMID: 10950832.

View in:
PubMed
   Mentions:
30
   Fields:
   Translation:
Animals Cells
Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo. J Clin Invest. 2000 Aug; 106(3):421-30. Getty L, Panteleon AE, Mittelman SD, Dea MK, Bergman RN. PMID: 10930445; PMCID: PMC314322.

View in:
PubMed
   Mentions:
15
   Fields:
   Translation:
Animals Cells
Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes. 2000 Mar; 49(3):399-408. Carpentier A, Mittelman SD, Bergman RN, Giacca A, Lewis GF. PMID: 10868961.

View in:
PubMed
   Mentions:
66
   Fields:
   Translation:
Humans
Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. Am J Physiol. 1999 06; 276(6):E1055-66. Carpentier A, Mittelman SD, Lamarche B, Bergman RN, Giacca A, Lewis GF. PMID: 10362618.

View in:
PubMed
   Mentions:
69
   Fields:
   Translation:
Humans
Role of portal insulin delivery in the disappearance of intravenous glucose and assessment of insulin sensitivity. Diabetes. 1998 May; 47(5):714-20. Steil GM, Rebrin K, Mittelman SD, Bergman RN. PMID: 9588441.

View in:
PubMed
   Mentions:
4
   Fields:
   Translation:
Animals
Central role of the adipocyte in insulin resistance. J Basic Clin Physiol Pharmacol. 1998; 9(2-4):205-21. Bergman RN, Mittelman SD. PMID: 10212835.

View in:
PubMed
   Mentions:
26
   Fields:
   Translation:
Humans Cells
Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. J Clin Invest. 1997 Dec 15; 100(12):3121-30. Mittelman SD, Fu YY, Rebrin K, Steil G, Bergman RN. PMID: 9399959; PMCID: PMC508525.

View in:
PubMed
   Mentions:
24
   Fields:
   Translation:
Animals
Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs. J Clin Invest. 1996 Aug 01; 98(3):741-9. Rebrin K, Steil GM, Mittelman SD, Bergman RN. PMID: 8698866; PMCID: PMC507484.

View in:
PubMed
   Mentions:
86
   Fields:
   Translation:
Animals Cells