Welcome to the i2b2 Community Wiki - i2b2 Community Wiki - i2b2 Community Wiki

Welcome to the i2b2 Community Wiki - i2b2 Community Wiki - i2b2 Community Wiki
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Welcome to the i2b2 Community Wiki
i2b2 Community Wiki
i2b2
Created by
nich
, last modified by
Jeff Klann
on
Sep 30, 2025
i2b2 is an open-source clinical data warehousing and analytics research platform used at over 250 locations worldwide. i2b2 enables sharing, integration, standardization, and analysis of heterogenous data from healthcare and research.
The i2b2 Community is a life-sciences-focused open-source, open-data community.
This wiki is the central place for the i2b2 Community to communicate and share projects with other users. Here you will find the latest information on the i2b2 Software, what others in the community are doing, and find resources to help answer any questions you may have about the i2b2.
i2b2 is part of the
i2b2 tranSMART Foundation
, which brings together an NIH-funded enterprise clinical research platform (i2b2) and pharma-developed software for translational research studies (tranSMART).
Project
Management
Ontology
Management
Data
Repository
(CRC)
File
Repository
(CRC)
Workflow
Framework
Identity
Management
i2b2
Web Client
Application
i2b2
Workbench
Application
i2b2 Hive
Older, unsupported add-ons are on the
Archived Optional Components
page.
Project Management
Core Server Side i2b2 Cell
This cell is used to provide user authentication and manage group and role information. It also keeps track of what cells are part of the hive.
Installation Guide
Messaging Guide
Design Document
Go to Download
Ontology Management
Core Server Side i2b2 Cell
This cell manages the terminology and knowledge information typically used in the hive. It is contacted for, or distributes knowledge to, cells during most of the hives transactions.
Installation Guide
Messaging Guide
Design Document
Architecture Document
Go to Download
Data Repository (CRC)
Core Server Side i2b2 Cell
This cell holds the phenotypic and genotypic data of the hive in a structured format. Data queries and visualizations are available through this cell.
Installation Guide
Messaging Guide
Design Document
Architecture Document
Plugin Analysis Document
Go to Download
Workplace Framework
Core Server Side i2b2 Cell
This cell is used to process information in steps through various parts of the hive. Most processed information will come to reside in the Data Repository Cell or as a display to the user.
Installation Guide
Messaging Guide
Design Document
Architecture Document
Go to Download
i2b2 Web Client
The i2b2 Web Client is a collection of client-side components designed as an YUI AJAX-based plug-ins that communicate with i2b2 Cells and allow the investigator to query and display the data of the hive.
Install Guide
Project Request Guide
Go to Download
i2b2 Hive
The Hive is a collection of software modules that create a system to allow the use of patient data for research.
i2b2 Hive Introduction
i2b2 Message Wrapper
i2b2 Patient Data Object
i2b2 Workbench
The i2b2 Workbench is a collection of client-side components designed as Eclipse-based java plug-ins that communicate with i2b2 Cells and allow the investigator to query, analyze, and display the data of the hive, generally in greater depth than the web client.
Installation Guide
Tutorial Document
Developer's Guide
Go to Download
Go to Download Source
File Repository
Core Server Side i2b2 Cell
This cell holds large files of data including radiological images and genetic sequences. The files are generally referenced from the Data Repository Cell.
Installation Guide
Messaging Guide
Architecture Document
Go to Download
Identity Management
Core Server Side i2b2 Cell
This cell is used to manage a patient's protected health information in a manner consistent with the HIPAA privacy rule. Patient data is available only as a HIPAA defined "Limited Data Set" to most of the hive.
Installation Guide
Messaging Guide
Design Document
Architecture Document
Go to Download
Documentation
Get Software
Current Announcements
Getting Started
Installation Guide
Upgrade Guide
Videos and Tutorials
Troubleshooting FAQ
Ontology Tutorials
(NEW!)
i2b2 Common Data Model Guide
Bundle Install Guides
For Developers
Server-side Messaging
Server Architecture
Server-side Design
Web Client Design
Release Notes
For End Users
Web Client Help
Workbench User Guide
Software
Version
i2b2 Binary Download
1.8.2 (September 2025)
Download Full
Download Upgrade
i2b2 Core Server Source Code
1.8.2 (September 2025)
Release i2b2 Core Server
i2b2 Core Data Source Code
1.8.2 (September 2025)
Release i2b2 Data
i2b2 Web Client
1.8.2 (September 2025)
Release i2b2 Web client
i2b2 Documentation
1.8.2 (September 2025)
1.8.2 Release Notes
Upgrade to version 1.8.2
i2b2 Installation Guide
i2b2 VMWare Server/Client Demo
1.8.2
Windows
Mac
i2b2 Docker Demo
(unofficial)
1.8.1a
Pittsburgh version
or
Boston version
i2b2 Workbench
2.0.01 (October 17, 2017)
Software Release 2.0.01
09/2025:
i2b2 release 1.8.2
available!
Enhanced Data Export extension for i2b2 with:
Export of user-designed analytic tables
Table designer plugin
Data export manager
ACT Version 4.2 Ontology
Digital Twin Bundle
User session log rotation (performance enhancement)
Faster patient counting scripts (for all databases)
Enhancements and bugfixes
Newest i2b2 Community Projects
Links and Older Announcements
Accrual to Clinical Trials
The Accrual to Clinical Trials (ACT) project goal is to create a federated network of National Clinical and Translational Science Award (CTSA) Consortium institutions to significantly increase participant accrual to the nation's highest priority clinical trials.
Multi-fact Table
The multi-fact table project is a new feature introduced in 1.7.09 that enables the i2b2 to query more than one fact table.

This new feature empowers the i2b2 to adapt to the needs of such projects as the Patient Centered Outcome Research Institute (PCORI) network and the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM). It can also be used for sites that want to be able to query both genomic and phenotype data but don't want the data to reside in a single table.
OMOP
The legacy i2b2 data model is comprised of a central fact table (observation_fact) surrounded by multiple dimension tables (star schema). In the Observation Medical Outcomes Partnership (OMOP) Clinical Data Model (CDM) rather than a central fact table, we have a collection of them distinguished by domain: procedures, condition, drug, measurement, observation, etc. In this project, we modify the CRC to run queries against multiple domain fact tables as dictated by the metadata.
RDF to i2b2 Conversion
Synthea data in i2b2
Synthea synthetic data can now be loaded into i2b2 for testing. A 63k sample of SyntheticMass patients is available for download.
i2b2 on Genomics Data
This community project extends the current i2b2 query functionality by providing the ability to query for genotyped subjects by specific annotations related to genetic variants. Also, new query widgets have been built in the i2b2 web client that leverages existing i2b2 infrastructure for querying large strings of text stored in the observation_blob field of the observation_fact table.
See All Community Projects
Important links:
1.7.13 Release and Classic webclient downloads are available at
i2b2 Software Downloads Links - All Releases
i2b2 tranSMART Working Groups
New Project:
i2b2 on OMOP
New Project:
i2b2 on Genomics Data
Older Announcements:
Consortium for Clinical Characterization of Covid-19 by EHR (4CE)
4CE is an international consortium for electronic health record (EHR) data-driven studies of the COVID-19 pandemic. The goal of this effort—led by the
i2b2 international academics users group
—is to inform doctors, epidemiologists and the public about COVID-19 patients with data acquired through the health care process.
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